| Saturday, February 4 |
| Future Tiger Chris Bando is born in Cleveland, OH. |
| Sunday, February 19 |
| Former Tiger Ray Demmitt dies in Glen Ellyn, IL at the age of 73. |
| Friday, March 30 |
| Future Tiger Jack Lazorko is born in Hoboken, NJ. |
| Wednesday, April 11 |
| Future Tiger John Martin is born in Wyandotte, MI. |
| Tuesday, April 17 |
| » Lost to Athletics (1-0), 2-1 | Tiger Stadium (0-1) | 0-1 | |
| » Starters: Alex Kellner vs Frank Lary | Second | 1 out |
| » Major-league debuts: Mike Baxes (Athletics) |
| Thursday, April 19 |
| » Lost to Athletics (2-0), 4-1 | Tiger Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Bobby Shantz vs Steve Gromek | Fifth | 2½ out |
| Friday, April 20 |
| » Lost to Indians (1-2), 3-1 | Cleveland Stadium (0-1) | 0-3 | Lost 3 |
| » Starters: Ned Garver vs Early Wynn | Sixth | 3 out |
| Saturday, April 21 |
| » Defeated Indians (1-3), 7-6 | Cleveland Stadium (1-1) | 1-3 | |
| » Starters: Bob Miller vs Mike Garcia | Fifth | 2½ out |
| Sunday, April 22 |
| » Defeated Indians (1-4), 6-4 | Cleveland Stadium (2-1) | 2-3 | Won 2 |
| » Starters: Frank Lary vs Bob Feller | Sixth | 3 out |
| » Lost to Indians (2-4), 5-2 | Cleveland Stadium (2-2) | 2-4 | |
| » Starters: Dick Marlowe vs Bob Lemon | Sixth | 3 out |
| Tuesday, April 24 |
| » Defeated Athletics (3-3), 7-4 | Municipal Stadium (1-0) | 3-4 | |
| » Starters: Steve Gromek vs Arnie Portocarrero | Fourth | 3 out |
| Wednesday, April 25 |
| Future Tiger Larry Pashnick is born in Lincoln Park, MI. |
| Friday, April 27 |
| » Lost to Indians (5-4), 4-3 | Tiger Stadium (0-3) | 3-5 | |
| » Starters: Mike Garcia vs Frank Lary | Fifth | 3 out |
| Sunday, April 29 |
| » Defeated Indians (5-5), 1-0 | Tiger Stadium (1-3) | 4-5 | |
| » Starters: Herb Score vs Billy Hoeft | Sixth | 3 out |
| » Lost to Indians (6-5), 8-4 | Tiger Stadium (1-4) | 4-6 | |
| » Starters: Bob Lemon vs Bud Black | Sixth | 3 out |
| Tuesday, May 1 |
| » Lost to Yankees (9-3), 9-2 | Yankee Stadium (0-1) | 4-7 | Lost 2 |
| » Starters: Steve Gromek vs Whitey Ford | Sixth | 4½ out |
| Wednesday, May 2 |
| » Defeated Yankees (9-4), 8-1 | Yankee Stadium (1-1) | 5-7 | |
| » Starters: Frank Lary vs Johnny Kucks | Sixth | 2½ out |
| Thursday, May 3 |
| » Lost to Red Sox (6-6), 5-2 | Fenway Park (0-1) | 5-8 | |
| » Starters: Duke Maas vs Frank Sullivan | Seventh | 3½ out |
| Friday, May 4 |
| » Lost to Red Sox (7-6), 6-4 | Fenway Park (0-2) | 5-9 | Lost 2 |
| » Starters: Paul Foytack vs Mel Parnell | Eighth | 4½ out |
| Saturday, May 5 |
| » Defeated Red Sox (7-7), 16-4 | Fenway Park (1-2) | 6-9 | |
| » Starters: Billy Hoeft vs Ike Delock | Sixth | 4½ out |
| Sunday, May 6 |
| » Lost to Orioles (7-11), 6-2 | Memorial Stadium (0-1) | 6-10 | |
| » Starters: Steve Gromek vs Ray Moore | Eighth | 6½ out |
| » Lost to Orioles (8-11), 4-3 | Memorial Stadium (0-2) | 6-11 | Lost 2 |
| » Starters: Frank Lary vs Erv Palica | Eighth | 6½ out |
| Monday, May 7 |
| » Lost to Orioles (9-11), 4-3 | Memorial Stadium (0-3) | 6-12 | Lost 3 |
| » Starters: Virgil Trucks vs Bill Wight | Eighth | 7 out |
| Tuesday, May 8 |
| » Defeated Senators (9-11), 14-6 | Griffith Stadium (1-0) | 7-12 | |
| » Starters: Duke Maas vs Dean Stone | Eighth | 7 out |
| Wednesday, May 9 |
| » Defeated Senators (9-12), 7-3 | Griffith Stadium (2-0) | 8-12 | Won 2 |
| » Starters: Paul Foytack vs Camilo Pascual | Eighth | 6 out |
| Friday, May 11 |
| » Lost to White Sox (8-8), 9-7 | Tiger Stadium (1-5) | 8-13 | |
| » Starters: Jack Harshman vs Frank Lary | Eighth | 6½ out |
| Saturday, May 12 |
| » Lost to White Sox (9-8), 7-6 | Tiger Stadium (1-6) | 8-14 | Lost 2 |
| » Starters: Dick Donovan vs Billy Hoeft | Eighth | 6½ out |
| Sunday, May 13 |
| » Lost to White Sox (10-8), 8-1 | Tiger Stadium (1-7) | 8-15 | Lost 3 |
| » Starters: Billy Pierce vs Virgil Trucks | Eighth | 7 out |
| Tuesday, May 15 |
| » Defeated Red Sox (11-11), 6-3 | Tiger Stadium (2-7) | 9-15 | |
| » Starters: Willard Nixon vs Paul Foytack | Eighth | 6 out |
| Wednesday, May 16 |
| » Lost to Red Sox (12-11), 4-2 | Tiger Stadium (2-8) | 9-16 | |
| » Starters: Mel Parnell vs Frank Lary | Eighth | 7 out |
| Friday, May 18 |
| » Defeated Orioles (14-15), 3-2 | Tiger Stadium (3-8) | 10-16 | |
| » Starters: Don Ferrarese vs Billy Hoeft | Seventh | 7½ out |
| Saturday, May 19 |
| » Lost to Orioles (15-15), 5-4 | Tiger Stadium (3-9) | 10-17 | |
| » Starters: Bill Wight vs Duke Maas | Seventh | 8½ out |
| Future Tiger Luis Salazar is born in Barcelona, Venezuela. |
| Sunday, May 20 |
| » Defeated Senators (12-17), 4-2 | Tiger Stadium (4-9) | 11-17 | |
| » Starters: Chuck Stobbs vs Paul Foytack | Sixth | 8 out |
| » Defeated Senators (12-18), 7-1 | Tiger Stadium (5-9) | 12-17 | Won 2 |
| » Starters: Hal Griggs vs Virgil Trucks | Sixth | 8 out |
| Tuesday, May 22 |
| » Defeated Yankees (22-11), 3-2 | Tiger Stadium (6-9) | 13-17 | Won 3 |
| » Starters: Whitey Ford vs Frank Lary | Sixth | 7½ out |
| Wednesday, May 23 |
| » Lost to Yankees (23-11), 13-5 | Tiger Stadium (6-10) | 13-18 | |
| » Starters: Rip Coleman vs Billy Hoeft | Sixth | 8½ out |
| Thursday, May 24 |
| » Lost to Yankees (24-11), 11-4 | Tiger Stadium (6-11) | 13-19 | Lost 2 |
| » Starters: Bob Turley vs Duke Maas | Sixth | 9½ out |
| Friday, May 25 |
| » Lost to Athletics (13-19), 6-3 | Tiger Stadium (6-12) | 13-20 | Lost 3 |
| » Starters: Lou Kretlow vs Paul Foytack | Seventh | 10½ out |
| Saturday, May 26 |
| » Defeated Athletics (13-20), 12-6 | Tiger Stadium (7-12) | 14-20 | |
| » Starters: Jack Crimian vs Billy Hoeft | Sixth | 9½ out |
| Former Tiger Al Simmons dies in Milwaukee, WI at the age of 55. |
| Sunday, May 27 |
| » Defeated Athletics (13-21), 8-2 | Tiger Stadium (8-12) | 15-20 | Won 2 |
| » Starters: Troy Herriage vs Frank Lary | Sixth | 9½ out |
| » Lost to Athletics (14-21), 5-0 | Tiger Stadium (8-13) | 15-21 | |
| » Starters: Art Ditmar vs Duke Maas | Sixth | 9½ out |
| Monday, May 28 |
| » Defeated Indians (20-15), 3-1 | Cleveland Stadium (3-2) | 16-21 | |
| » Starters: Steve Gromek vs Herb Score | Sixth | 9½ out |
| Wednesday, May 30 |
| » Defeated Athletics (15-23), 11-3 | Municipal Stadium (2-0) | 17-21 | Won 2 |
| » Starters: Paul Foytack vs Lou Kretlow | Sixth | 9 out |
| » Defeated Athletics (15-24), 5-1 | Municipal Stadium (3-0) | 18-21 | Won 3 |
| » Starters: Virgil Trucks vs Art Ditmar | Sixth | 9 out |
| Friday, June 1 |
| » Defeated Yankees (29-14), 6-3 | Yankee Stadium (2-1) | 19-21 | Won 4 |
| » Starters: Frank Lary vs Tommy Byrne | Sixth | 8½ out |
| Sunday, June 3 |
| » Defeated Yankees (29-15), 6-3 | Yankee Stadium (3-1) | 20-21 | Won 5 |
| » Starters: Billy Hoeft vs Whitey Ford | Fourth | 6½ out |
| » Defeated Yankees (29-16), 7-4 | Yankee Stadium (4-1) | 21-21 | Won 6 |
| » Starters: Steve Gromek vs Don Larsen | Fourth | 6½ out |
| Tuesday, June 5 |
| » Defeated Red Sox (21-22), 14-11 | Fenway Park (2-2) | 22-21 | Won 7 |
| » Starters: Virgil Trucks vs Bob Porterfield | Fourth | 5½ out |
| Wednesday, June 6 |
| » Lost to Red Sox (22-22), 5-4 | Fenway Park (2-3) | 22-22 | |
| » Starters: Paul Foytack vs Tom Brewer | Fourth | 6½ out |
| Thursday, June 7 |
| » Lost to Red Sox (23-22), 6-5 | Fenway Park (2-4) | 22-23 | Lost 2 |
| » Starters: Frank Lary vs Frank Sullivan | Fifth | 7½ out |
| Friday, June 8 |
| » Defeated Senators (20-30), 7-0 | Griffith Stadium (3-0) | 23-23 | |
| » Starters: Billy Hoeft vs Camilo Pascual | Fifth | 6½ out |
| Saturday, June 9 |
| » Defeated Senators (20-31), 5-3 | Griffith Stadium (4-0) | 24-23 | Won 2 |
| » Starters: Steve Gromek vs Hal Griggs | Fourth | 5½ out |
| Sunday, June 10 |
| » Lost to Senators (21-31), 6-5 | Griffith Stadium (4-1) | 24-24 | |
| » Starters: Virgil Trucks vs Chuck Stobbs | Fifth | 7 out |
| » Lost to Senators (22-31), 12-9 | Griffith Stadium (4-2) | 24-25 | Lost 2 |
| » Starters: Paul Foytack vs Bob Wiesler | Fifth | 7 out |
| Monday, June 11 |
| » Lost to Orioles (25-27), 5-4 | Memorial Stadium (0-4) | 24-26 | Lost 3 |
| » Starters: Frank Lary vs Don Ferrarese | Sixth | 7½ out |
| Tuesday, June 12 |
| » Defeated Orioles (25-28), 8-1 | Memorial Stadium (1-4) | 25-26 | |
| » Starters: Billy Hoeft vs Bill Wight | Fifth | 7½ out |
| Wednesday, June 13 |
| » Defeated Orioles (25-29), 2-0 | Memorial Stadium (2-4) | 26-26 | Won 2 |
| » Starters: Paul Foytack vs Billy Loes | Fifth | 6½ out |
| Friday, June 15 |
| » Defeated Red Sox (27-26), 5-2 | Tiger Stadium (9-13) | 27-26 | Won 3 |
| » Starters: Bob Porterfield vs Frank Lary | Fourth | 7 out |
| Future Tiger Lance Parrish is born in Clairton, PA. |
| Saturday, June 16 |
| » Lost to Red Sox (28-26), 6-5 | Tiger Stadium (9-14) | 27-27 | |
| » Starters: Tom Brewer vs Steve Gromek | Fourth | 8 out |
| Sunday, June 17 |
| » Lost to Red Sox (29-26), 13-2 | Tiger Stadium (9-15) | 27-28 | Lost 2 |
| » Starters: Frank Sullivan vs Billy Hoeft | Fifth | 9 out |
| Monday, June 18 |
| » Lost to Yankees (38-20), 7-4 | Tiger Stadium (9-16) | 27-29 | Lost 3 |
| » Starters: Bob Turley vs Paul Foytack | Sixth | 10 out |
| Tuesday, June 19 |
| » Lost to Yankees (39-20), 5-3 | Tiger Stadium (9-17) | 27-30 | Lost 4 |
| » Starters: Bob Grim vs Frank Lary | Fifth | 11 out |
| Wednesday, June 20 |
| » Lost to Yankees (40-20), 4-1 | Tiger Stadium (9-18) | 27-31 | Lost 5 |
| » Starters: Johnny Kucks vs Billy Hoeft | Sixth | 12 out |
| Friday, June 22 |
| » Lost to Orioles (29-33), 3-2 | Tiger Stadium (9-19) | 27-32 | Lost 6 |
| » Starters: Bill Wight vs Paul Foytack | Sixth | 12 out |
| Sunday, June 24 |
| » Lost to Orioles (30-33), 3-2 | Tiger Stadium (9-20) | 27-33 | Lost 7 |
| » Starters: Billy Loes vs Steve Gromek | Sixth | 11½ out |
| » Lost to Orioles (31-33), 3-2 | Tiger Stadium (9-21) | 27-34 | Lost 8 |
| » Starters: Ray Moore vs Frank Lary | Sixth | 11½ out |
| Monday, June 25 |
| » Lost to Senators (27-42), 5-3 | Tiger Stadium (9-22) | 27-35 | Lost 9 |
| » Starters: Camilo Pascual vs Billy Hoeft | Sixth | 12½ out |
| Tuesday, June 26 |
| » Tied Senators, 2-2 | Tiger Stadium (9-22) | 27-35 | |
| » Starters: Bunky Stewart vs Paul Foytack | Sixth | 13 out |
| Wednesday, June 27 |
| » Lost to Senators (28-42), 3-1 | Tiger Stadium (9-23) | 27-36 | Lost 10 |
| » Starters: Bob Wiesler vs Frank Lary | Sixth | 14 out |
| Thursday, June 28 |
| » Defeated Athletics (25-42), 4-0 | Municipal Stadium (4-0) | 28-36 | |
| » Starters: Virgil Trucks vs Jack McMahan | Sixth | 13½ out |
| Friday, June 29 |
| » Defeated Athletics (25-43), 5-0 | Municipal Stadium (5-0) | 29-36 | Won 2 |
| » Starters: Billy Hoeft vs Tom Lasorda | Sixth | 13½ out |
| Saturday, June 30 |
| » Defeated Athletics (25-44), 14-2 | Municipal Stadium (6-0) | 30-36 | Won 3 |
| » Starters: Paul Foytack vs Alex Kellner | Fifth | 12½ out |
| Sunday, July 1 |
| » Lost to Athletics (26-44), 4-3 | Municipal Stadium (6-1) | 30-37 | |
| » Starters: Frank Lary vs Troy Herriage | Sixth | 14 out |
| Monday, July 2 |
| » Lost to White Sox (40-26), 9-3 | Tiger Stadium (9-24) | 30-38 | Lost 2 |
| » Starters: Howie Pollet vs Virgil Trucks | Sixth | 14½ out |
| Tuesday, July 3 |
| » Lost to White Sox (41-26), 6-0 | Tiger Stadium (9-25) | 30-39 | Lost 3 |
| » Starters: Jim Wilson vs Billy Hoeft | Sixth | 15½ out |
| Wednesday, July 4 |
| » Lost to Indians (41-29), 6-4 | Tiger Stadium (9-26) | 30-40 | Lost 4 |
| » Starters: Herb Score vs Paul Foytack | Sixth | 16½ out |
| » Lost to Indians (42-29), 3-1 | Tiger Stadium (9-27) | 30-41 | Lost 5 |
| » Starters: Early Wynn vs Duke Maas | Sixth | 16½ out |
| Thursday, July 5 |
| » Defeated Indians (42-30), 13-7 | Tiger Stadium (10-27) | 31-41 | |
| » Starters: Bob Lemon vs Frank Lary | Sixth | 16½ out |
| Friday, July 6 |
| » Lost to White Sox (43-27), 14-0 | Comiskey Park I (0-1) | 31-42 | |
| » Starters: Steve Gromek vs Jack Harshman | Sixth | 17½ out |
| Saturday, July 7 |
| » Defeated White Sox (43-28), 12-8 | Comiskey Park I (1-1) | 32-42 | |
| » Starters: Billy Hoeft vs Dick Donovan | Sixth | 17½ out |
| Sunday, July 8 |
| » Defeated White Sox (43-29), 17-5 | Comiskey Park I (2-1) | 33-42 | Won 2 |
| » Starters: Paul Foytack vs Jim Wilson | Fifth | 17 out |
| » Defeated White Sox (43-30), 8-6 | Comiskey Park I (3-1) | 34-42 | Won 3 |
| » Starters: Frank Lary vs Billy Pierce | Fifth | 17 out |
| Thursday, July 12 |
| » Defeated Senators (31-51), 4-2 | Griffith Stadium (5-2) | 35-42 | Won 4 |
| » Starters: Billy Hoeft vs Bob Wiesler | Fifth | 17 out |
| Friday, July 13 |
| » Lost to Senators (32-51), 12-11 | Griffith Stadium (5-3) | 35-43 | |
| » Starters: Paul Foytack vs Pedro Ramos | Fifth | 18 out |
| Saturday, July 14 |
| » Defeated Senators (32-52), 6-5 | Griffith Stadium (6-3) | 36-43 | |
| » Starters: Frank Lary vs Camilo Pascual | Fifth | 18 out |
| Sunday, July 15 |
| » Lost to Orioles (36-44), 7-2 | Memorial Stadium (2-5) | 36-44 | |
| » Starters: Ned Garver vs Ray Moore | Sixth | 20 out |
| » Lost to Orioles (37-44), 6-3 | Memorial Stadium (2-6) | 36-45 | Lost 2 |
| » Starters: Virgil Trucks vs Hal Brown | Sixth | 20 out |
| Tuesday, July 17 |
| » Lost to Yankees (58-26), 4-0 | Yankee Stadium (4-2) | 36-46 | Lost 3 |
| » Starters: Billy Hoeft vs Johnny Kucks | Sixth | 21 out |
| Wednesday, July 18 |
| » Defeated Yankees (58-27), 8-4 | Yankee Stadium (5-2) | 37-46 | |
| » Starters: Paul Foytack vs Tom Sturdivant | Sixth | 19 out |
| » Defeated Yankees (58-28), 4-3 | Yankee Stadium (6-2) | 38-46 | Won 2 |
| » Starters: Frank Lary vs Mickey McDermott | Sixth | 19 out |
| Thursday, July 19 |
| » Lost to Yankees (59-28), 7-3 | Yankee Stadium (6-3) | 38-47 | |
| » Starters: Duke Maas vs Tommy Byrne | Sixth | 20 out |
| Friday, July 20 |
| » Defeated Red Sox (47-39), 9-6 | Fenway Park (3-4) | 39-47 | |
| » Starters: Virgil Trucks vs Willard Nixon | Sixth | 20 out |
| Saturday, July 21 |
| » Lost to Red Sox (48-39), 9-3 | Fenway Park (3-5) | 39-48 | |
| » Starters: Billy Hoeft vs Frank Sullivan | Sixth | 20½ out |
| Sunday, July 22 |
| » Lost to Red Sox (49-39), 8-6 | Fenway Park (3-6) | 39-49 | Lost 2 |
| » Starters: Frank Lary vs Tom Brewer | Sixth | 21 out |
| Tuesday, July 24 |
| » Defeated Orioles (40-49), 9-7 | Tiger Stadium (11-27) | 40-49 | |
| » Starters: Connie Johnson vs Paul Foytack | Sixth | 20½ out |
| » Lost to Orioles (41-49), 11-5 | Tiger Stadium (11-28) | 40-50 | |
| » Starters: Don Ferrarese vs Bob Miller | Sixth | 20½ out |
| Wednesday, July 25 |
| » Defeated Orioles (41-50), 6-2 | Tiger Stadium (12-28) | 41-50 | |
| » Starters: Ray Moore vs Virgil Trucks | Fifth | 20½ out |
| Thursday, July 26 |
| » Lost to Orioles (42-50), 11-6 | Tiger Stadium (12-29) | 41-51 | |
| » Starters: Bill Wight vs Billy Hoeft | Sixth | 21½ out |
| Friday, July 27 |
| » Defeated Senators (36-59), 5-4 | Tiger Stadium (13-29) | 42-51 | |
| » Starters: Bob Wiesler vs Frank Lary | Fifth | 21½ out |
| Saturday, July 28 |
| » Lost to Senators (37-59), 6-5 | Tiger Stadium (13-30) | 42-52 | |
| » Starters: Pedro Ramos vs Paul Foytack | Sixth | 22½ out |
| Sunday, July 29 |
| » Defeated Senators (37-60), 6-0 | Tiger Stadium (14-30) | 43-52 | |
| » Starters: Bunky Stewart vs Billy Hoeft | Fifth | 23 out |
| » Lost to Senators (38-60), 4-1 | Tiger Stadium (14-31) | 43-53 | |
| » Starters: Dean Stone vs Jim Bunning | Fifth | 23 out |
| Monday, July 30 |
| » Defeated Red Sox (53-43), 4-1 | Tiger Stadium (15-31) | 44-53 | |
| » Starters: Frank Sullivan vs Virgil Trucks | Fifth | 23 out |
| Tuesday, July 31 |
| » Defeated Red Sox (53-44), 6-4 | Tiger Stadium (16-31) | 45-53 | Won 2 |
| » Starters: Bob Porterfield vs Frank Lary | Fifth | 22 out |
| Wednesday, August 1 |
| » Lost to Red Sox (54-44), 5-4 | Tiger Stadium (16-32) | 45-54 | |
| » Starters: Tom Brewer vs Paul Foytack | Fifth | 22 out |
| Thursday, August 2 |
| » Lost to Red Sox (55-44), 18-3 | Tiger Stadium (16-33) | 45-55 | Lost 2 |
| » Starters: Willard Nixon vs Bob Miller | Fifth | 22 out |
| Friday, August 3 |
| » Defeated Yankees (67-34), 10-4 | Tiger Stadium (17-33) | 46-55 | |
| » Starters: Whitey Ford vs Billy Hoeft | Fifth | 21 out |
| Saturday, August 4 |
| » Defeated Yankees (67-35), 5-4 | Tiger Stadium (18-33) | 47-55 | Won 2 |
| » Starters: Bob Turley vs Virgil Trucks | Fifth | 20 out |
| Sunday, August 5 |
| » Defeated Yankees (67-36), 8-5 | Tiger Stadium (19-33) | 48-55 | Won 3 |
| » Starters: Johnny Kucks vs Frank Lary | Fifth | 19 out |
| Future Tiger Dave Rozema is born in Grand Rapids, MI. |
| Monday, August 6 |
| » Defeated Indians (59-43), 9-0 | Tiger Stadium (20-33) | 49-55 | Won 4 |
| » Starters: Herb Score vs Paul Foytack | Fifth | 19 out |
| Tuesday, August 7 |
| » Lost to Indians (60-43), 5-2 | Tiger Stadium (20-34) | 49-56 | |
| » Starters: Mike Garcia vs Frank Lary | Fifth | 19 out |
| Wednesday, August 8 |
| » Defeated Athletics (36-69), 8-7 | Tiger Stadium (21-34) | 50-56 | |
| » Starters: Art Ditmar vs Billy Hoeft | Fifth | 19 out |
| Thursday, August 9 |
| » Lost to Athletics (37-69), 5-3 | Tiger Stadium (21-35) | 50-57 | |
| » Starters: Jack McMahan vs Virgil Trucks | Fifth | 20 out |
| Future Tiger Kevin Saucier is born in Pensacola, FL. |
| Friday, August 10 |
| » Lost to White Sox (56-48), 6-1 | Tiger Stadium (21-36) | 50-58 | Lost 2 |
| » Starters: Dick Donovan vs Paul Foytack | Fifth | 21 out |
| Saturday, August 11 |
| » Defeated White Sox (56-49), 5-1 | Tiger Stadium (22-36) | 51-58 | |
| » Starters: Jim Wilson vs Frank Lary | Fifth | 20 out |
| Sunday, August 12 |
| » Defeated White Sox (56-50), 5-2 | Tiger Stadium (23-36) | 52-58 | Won 2 |
| » Starters: Billy Pierce vs Billy Hoeft | Fifth | 20½ out |
| Tuesday, August 14 |
| » Defeated Indians (63-46), 6-4 | Cleveland Stadium (4-2) | 53-58 | Won 3 |
| » Starters: Paul Foytack vs Early Wynn | Fifth | 20½ out |
| Wednesday, August 15 |
| » Defeated Indians (63-47), 1-0 | Cleveland Stadium (5-2) | 54-58 | Won 4 |
| » Starters: Frank Lary vs Bob Lemon | Fifth | 20½ out |
| Thursday, August 16 |
| » Lost to Indians (64-47), 5-4 | Cleveland Stadium (5-3) | 54-59 | |
| » Starters: Billy Hoeft vs Herb Score | Fifth | 20½ out |
| Friday, August 17 |
| » Lost to White Sox (60-50), 4-3 | Comiskey Park I (3-2) | 54-60 | Lost 2 |
| » Starters: Virgil Trucks vs Billy Pierce | Fifth | 20½ out |
| Saturday, August 18 |
| » Lost to White Sox (61-50), 2-1 | Comiskey Park I (3-3) | 54-61 | Lost 3 |
| » Starters: Paul Foytack vs Bob Keegan | Fifth | 22 out |
| Sunday, August 19 |
| » Defeated White Sox (61-51), 3-1 | Comiskey Park I (4-3) | 55-61 | |
| » Starters: Frank Lary vs Jack Harshman | Fifth | 21½ out |
| » Lost to White Sox (62-51), 4-1 | Comiskey Park I (4-4) | 55-62 | |
| » Starters: Billy Hoeft vs Dick Donovan | Fifth | 21½ out |
| Tuesday, August 21 |
| » Defeated Senators (49-67), 8-3 | Griffith Stadium (7-3) | 56-62 | |
| » Starters: Steve Gromek vs Hal Griggs | Fifth | 20½ out |
| Wednesday, August 22 |
| » Defeated Senators (49-68), 9-5 | Griffith Stadium (8-3) | 57-62 | Won 2 |
| » Starters: Paul Foytack vs Dean Stone | Fifth | 20½ out |
| Thursday, August 23 |
| » Lost to Orioles (54-65), 3-0 | Memorial Stadium (2-7) | 57-63 | |
| » Starters: Frank Lary vs Ray Moore | Fifth | 20 out |
| Friday, August 24 |
| » Defeated Orioles (54-66), 4-1 | Memorial Stadium (3-7) | 58-63 | |
| » Starters: Billy Hoeft vs Connie Johnson | Fifth | 20 out |
| Saturday, August 25 |
| » Defeated Orioles (54-67), 7-3 | Memorial Stadium (4-7) | 59-63 | Won 2 |
| » Starters: Jim Bunning vs Don Ferrarese | Fifth | 19 out |
| Sunday, August 26 |
| » Lost to Yankees (80-45), 7-0 | Yankee Stadium (6-4) | 59-64 | |
| » Starters: Paul Foytack vs Tom Sturdivant | Fifth | 19 out |
| » Defeated Yankees (80-46), 5-4 | Yankee Stadium (7-4) | 60-64 | |
| » Starters: Steve Gromek vs Mickey McDermott | Fifth | 19 out |
| Tuesday, August 28 |
| » Defeated Red Sox (67-57), 6-3 | Fenway Park (4-6) | 61-64 | Won 2 |
| » Starters: Frank Lary vs Mel Parnell | Fifth | 19 out |
| Wednesday, August 29 |
| » Lost to Red Sox (68-57), 4-2 | Fenway Park (4-7) | 61-65 | |
| » Starters: Billy Hoeft vs Tom Brewer | Fifth | 20 out |
| Thursday, August 30 |
| Future Tiger Steve Baker is born in Eugene, OR. |
| Friday, August 31 |
| » Defeated Athletics (41-85), 6-1 | Tiger Stadium (24-36) | 62-65 | |
| » Starters: Troy Herriage vs Paul Foytack | Fifth | 20 out |
| Saturday, September 1 |
| » Defeated Athletics (41-86), 6-1 | Tiger Stadium (25-36) | 63-65 | Won 2 |
| » Starters: Lou Kretlow vs Frank Lary | Fifth | 19 out |
| Sunday, September 2 |
| » Defeated Athletics (41-87), 3-1 | Tiger Stadium (26-36) | 64-65 | Won 3 |
| » Starters: Art Ditmar vs Billy Hoeft | Fifth | 18 out |
| Monday, September 3 |
| » Defeated White Sox (71-58), 11-8 | Comiskey Park I (5-4) | 65-65 | Won 4 |
| » Starters: Jim Bunning vs Jim Wilson | Fifth | 19 out |
| » Lost to White Sox (72-58), 5-3 | Comiskey Park I (5-5) | 65-66 | |
| » Starters: Steve Gromek vs Bob Keegan | Fifth | 19 out |
| Tuesday, September 4 |
| » Lost to White Sox (73-58), 11-4 | Comiskey Park I (5-6) | 65-67 | Lost 2 |
| » Starters: Paul Foytack vs Dick Donovan | Fifth | 19½ out |
| Thursday, September 6 |
| » Defeated Athletics (43-89), 6-0 | Municipal Stadium (7-1) | 66-67 | |
| » Starters: Frank Lary vs Art Ditmar | Fifth | 19½ out |
| Friday, September 7 |
| » Defeated Athletics (43-90), 12-8 | Municipal Stadium (8-1) | 67-67 | Won 2 |
| » Starters: Billy Hoeft vs Lou Kretlow | Fifth | 18½ out |
| Saturday, September 8 |
| » Defeated Athletics (43-91), 2-1 | Municipal Stadium (9-1) | 68-67 | Won 3 |
| » Starters: Paul Foytack vs Tom Gorman | Fourth | 18½ out |
| Sunday, September 9 |
| » Defeated Athletics (43-92), 7-3 | Municipal Stadium (10-1) | 69-67 | Won 4 |
| » Starters: Virgil Trucks vs Wally Burnette | Fourth | 18½ out |
| Tuesday, September 11 |
| » Defeated Senators (57-80), 12-0 | Tiger Stadium (27-36) | 70-67 | Won 5 |
| » Starters: Dean Stone vs Frank Lary | Fifth | 18½ out |
| Wednesday, September 12 |
| » Defeated Senators (57-81), 3-2 | Tiger Stadium (28-36) | 71-67 | Won 6 |
| » Starters: Evelio Hernandez vs Billy Hoeft | Fifth | 17½ out |
| » Major-league debuts: Charlie Lau (Tigers) |
| Future Tiger Mark Thurmond is born in Houston, TX. |
| Thursday, September 13 |
| » Defeated Senators (57-82), 7-2 | Tiger Stadium (29-36) | 72-67 | Won 7 |
| » Starters: Chuck Stobbs vs Paul Foytack | Fifth | 17½ out |
| Friday, September 14 |
| » Lost to Yankees (91-50), 5-1 | Tiger Stadium (29-37) | 72-68 | |
| » Starters: Don Larsen vs Hal Woodeshick | Fifth | 18½ out |
| » Major-league debuts: Hal Woodeshick (Tigers) |
| Saturday, September 15 |
| » Defeated Yankees (91-51), 6-2 | Tiger Stadium (30-37) | 73-68 | |
| » Starters: Rip Coleman vs Frank Lary | Fifth | 17½ out |
| Future Tiger John Pacella is born in Brooklyn, NY. |
| Sunday, September 16 |
| » Defeated Red Sox (79-64), 5-4 | Tiger Stadium (31-37) | 74-68 | Won 2 |
| » Starters: Frank Sullivan vs Billy Hoeft | Fifth | 16½ out |
| » Defeated Red Sox (79-65), 8-4 | Tiger Stadium (32-37) | 75-68 | Won 3 |
| » Starters: Willard Nixon vs Gene Host | Fifth | 16½ out |
| Tuesday, September 18 |
| » Defeated Orioles (62-82), 6-2 | Tiger Stadium (33-37) | 76-68 | Won 4 |
| » Starters: Connie Johnson vs Paul Foytack | Fifth | 16½ out |
| Wednesday, September 19 |
| » Defeated Orioles (62-83), 9-1 | Tiger Stadium (34-37) | 77-68 | Won 5 |
| » Starters: Hal Brown vs Frank Lary | Fifth | 16 out |
| » Major-league debuts: Gordie Sundin (Orioles) |
| Friday, September 21 |
| » Lost to Indians (84-63), 5-1 | Tiger Stadium (34-38) | 77-69 | |
| » Starters: Early Wynn vs Billy Hoeft | Fifth | 16 out |
| Saturday, September 22 |
| » Lost to Indians (85-63), 5-1 | Tiger Stadium (34-39) | 77-70 | Lost 2 |
| » Starters: Herb Score vs Paul Foytack | Fifth | 17 out |
| Sunday, September 23 |
| » Defeated Indians (85-64), 11-1 | Tiger Stadium (35-39) | 78-70 | |
| » Starters: Bob Lemon vs Frank Lary | Fifth | 17 out |
| Monday, September 24 |
| » Lost to White Sox (84-65), 14-11 | Tiger Stadium (35-40) | 78-71 | |
| » Starters: Bob Keegan vs Hal Woodeshick | Fifth | 17 out |
| Tuesday, September 25 |
| » Defeated White Sox (84-66), 5-3 | Tiger Stadium (36-40) | 79-71 | |
| » Starters: Dick Donovan vs Billy Hoeft | Fifth | 17 out |
| Wednesday, September 26 |
| » Defeated White Sox (84-67), 4-1 | Tiger Stadium (37-40) | 80-71 | Won 2 |
| » Starters: Jack Harshman vs Paul Foytack | Fifth | 16 out |
| Friday, September 28 |
| » Lost to Indians (88-64), 2-1 | Cleveland Stadium (5-4) | 80-72 | |
| » Starters: Billy Hoeft vs Hank Aguirre | Fifth | 17 out |
| Saturday, September 29 |
| » Defeated Indians (88-65), 9-1 | Cleveland Stadium (6-4) | 81-72 | |
| » Starters: Frank Lary vs Art Houtteman | Fifth | 16 out |
| Sunday, September 30 |
| » Defeated Indians (88-66), 8-4 | Cleveland Stadium (7-4) | 82-72 | Won 2 |
| » Starters: Ned Garver vs Bob Feller | Fifth | 15 out |
| Friday, November 30 |
| Future Tiger Dave Engle is born in San Diego, CA. |
| Tuesday, December 4 |
| Future Tiger Barbaro Garbey is born in Santiago De Cuba, Cuba. |
Game information provided by Retrosheet (www.retrosheet.org) |