| Wednesday, February 8 |
| Former Red Sox Long Tom Hughes dies in Chicago, IL at the age of 78. |
| Sunday, February 12 |
| Future Red Sox Brian Denman is born in Minneapolis, MN. |
| Saturday, February 25 |
| Former Red Sox Jack Lewis dies in Steubenville, OH at the age of 73. |
| Saturday, March 17 |
| Future Red Sox Tim Lollar is born in Poplar Bluff, MO. |
| Tuesday, April 17 |
| » Defeated Orioles (0-1), 8-1 | Fenway Park (1-0) | 1-0 | |
| » Starters: Bill Wight vs Frank Sullivan | First | -- |
| » Major-league debuts: Don Buddin (Red Sox) Tito Francona (Orioles) |
| Wednesday, April 18 |
| » Defeated Orioles (0-2), 8-4 | Fenway Park (2-0) | 2-0 | Won 2 |
| » Starters: Ray Moore vs Bob Porterfield | First | -- |
| Thursday, April 19 |
| » Defeated Orioles (0-3), 4-2 | Fenway Park (3-0) | 3-0 | Won 3 |
| » Starters: Erv Palica vs Tom Brewer | First | -- |
| Friday, April 20 |
| » Lost to Yankees (3-1), 7-1 | Yankee Stadium (0-1) | 3-1 | |
| » Starters: Willard Nixon vs Whitey Ford | Second | ½ out |
| Saturday, April 21 |
| » Lost to Yankees (4-1), 14-10 | Yankee Stadium (0-2) | 3-2 | Lost 2 |
| » Starters: George Susce vs Bob Turley | Third | 1 out |
| » Major-league debuts: Marty Keough and Dave Sisler (Red Sox) |
| Sunday, April 22 |
| » Lost to Yankees (5-1), 13-6 | Yankee Stadium (0-3) | 3-3 | Lost 3 |
| » Starters: Frank Sullivan vs Don Larsen | Fourth | 2 out |
| Wednesday, April 25 |
| » Lost to Senators (4-5), 4-1 | Fenway Park (3-1) | 3-4 | Lost 4 |
| » Starters: Pedro Ramos vs Bob Porterfield | Fourth | 3½ out |
| Friday, April 27 |
| » Lost to Yankees (8-2), 5-2 | Fenway Park (3-2) | 3-5 | Lost 5 |
| » Starters: Don Larsen vs Tom Brewer | Fifth | 3 out |
| Saturday, April 28 |
| » Defeated Yankees (8-3), 6-4 | Fenway Park (4-2) | 4-5 | |
| » Starters: Bob Turley vs Frank Sullivan | Fifth | 2½ out |
| Tuesday, May 1 |
| » Lost to Athletics (4-6), 3-2 | Fenway Park (4-3) | 4-6 | |
| » Starters: Lou Kretlow vs Bob Porterfield | Fifth | 4 out |
| Wednesday, May 2 |
| » Defeated Athletics (4-7), 2-0 | Fenway Park (5-3) | 5-6 | |
| » Starters: Art Ditmar vs Tom Brewer | Fifth | 2 out |
| Thursday, May 3 |
| » Defeated Tigers (5-8), 5-2 | Fenway Park (6-3) | 6-6 | Won 2 |
| » Starters: Duke Maas vs Frank Sullivan | Fifth | 2 out |
| Friday, May 4 |
| » Defeated Tigers (5-9), 6-4 | Fenway Park (7-3) | 7-6 | Won 3 |
| » Starters: Paul Foytack vs Mel Parnell | Fourth | 2 out |
| Saturday, May 5 |
| » Lost to Tigers (6-9), 16-4 | Fenway Park (7-4) | 7-7 | |
| » Starters: Billy Hoeft vs Ike Delock | Fifth | 3 out |
| Monday, May 7 |
| » Defeated Indians (9-7), 5-1 | Fenway Park (8-4) | 8-7 | |
| » Starters: Mike Garcia vs Tom Brewer | Third | 3½ out |
| Tuesday, May 8 |
| » Defeated White Sox (6-7), 4-3 | Fenway Park (9-4) | 9-7 | Won 2 |
| » Starters: Billy Pierce vs Frank Sullivan | Second | 3½ out |
| Wednesday, May 9 |
| » Defeated White Sox (6-8), 7-5 | Fenway Park (10-4) | 10-7 | Won 3 |
| » Starters: Dick Donovan vs Bob Porterfield | Second | 2½ out |
| Thursday, May 10 |
| » Lost to White Sox (7-8), 2-1 | Fenway Park (10-5) | 10-8 | |
| » Starters: Connie Johnson vs Mel Parnell | Third | 2½ out |
| Friday, May 11 |
| » Lost to Senators (10-12), 4-3 | Griffith Stadium (0-1) | 10-9 | Lost 2 |
| » Starters: Ike Delock vs Chuck Stobbs | Third | 3½ out |
| Saturday, May 12 |
| » Lost to Senators (11-12), 12-9 | Griffith Stadium (0-2) | 10-10 | Lost 3 |
| » Starters: Tom Brewer vs Pedro Ramos | Fourth | 3½ out |
| Sunday, May 13 |
| » Defeated Senators (11-13), 5-3 | Griffith Stadium (1-2) | 11-10 | |
| » Starters: Frank Sullivan vs Camilo Pascual | Fourth | 3 out |
| Tuesday, May 15 |
| » Lost to Tigers (9-15), 6-3 | Tiger Stadium (0-1) | 11-11 | |
| » Starters: Willard Nixon vs Paul Foytack | Fourth | 3 out |
| Wednesday, May 16 |
| » Defeated Tigers (9-16), 4-2 | Tiger Stadium (1-1) | 12-11 | |
| » Starters: Mel Parnell vs Frank Lary | Fourth | 3 out |
| Thursday, May 17 |
| » Defeated Athletics (9-16), 6-1 | Municipal Stadium (1-0) | 13-11 | Won 2 |
| » Starters: Tom Brewer vs Troy Herriage | Fourth | 3 out |
| Friday, May 18 |
| » Defeated Athletics (9-17), 5-4 | Municipal Stadium (2-0) | 14-11 | Won 3 |
| » Starters: Frank Sullivan vs Art Ditmar | Third | 3 out |
| Saturday, May 19 |
| » Lost to Athletics (10-17), 5-4 | Municipal Stadium (2-1) | 14-12 | |
| » Starters: George Susce vs Lou Kretlow | Third | 4 out |
| Sunday, May 20 |
| » Defeated White Sox (12-12), 12-5 | Comiskey Park I (1-0) | 15-12 | |
| » Starters: Frank Baumann vs Dick Donovan | Third | 3½ out |
| » Defeated White Sox (12-13), 2-1 | Comiskey Park I (2-0) | 16-12 | Won 2 |
| » Starters: Ike Delock vs Bob Keegan | Third | 3½ out |
| Tuesday, May 22 |
| » Defeated Indians (18-12), 5-3 | Cleveland Stadium (1-0) | 17-12 | Won 3 |
| » Starters: Tom Brewer vs Early Wynn | Third | 3 out |
| Wednesday, May 23 |
| » Lost to Indians (19-12), 6-3 | Cleveland Stadium (1-1) | 17-13 | |
| » Starters: Frank Sullivan vs Herb Score | Third | 4 out |
| Friday, May 25 |
| » Lost to Senators (13-20), 10-5 | Fenway Park (10-6) | 17-14 | Lost 2 |
| » Starters: Pedro Ramos vs George Susce | Third | 5½ out |
| Saturday, May 26 |
| » Lost to Senators (14-20), 4-1 | Fenway Park (10-7) | 17-15 | Lost 3 |
| » Starters: Chuck Stobbs vs Ike Delock | Third | 5½ out |
| Sunday, May 27 |
| » Defeated Senators (14-21), 9-7 | Fenway Park (11-7) | 18-15 | |
| » Starters: Tex Clevenger vs Tom Brewer | Third | 5½ out |
| » Lost to Senators (15-21), 11-10 | Fenway Park (11-8) | 18-16 | |
| » Starters: Camilo Pascual vs Bob Porterfield | Third | 5½ out |
| Future Red Sox Mark Clear is born in Los Angeles, CA. |
| Monday, May 28 |
| » Lost to Yankees (26-12), 2-0 | Yankee Stadium (0-4) | 18-17 | Lost 2 |
| » Starters: Frank Sullivan vs Whitey Ford | Third | 6½ out |
| Tuesday, May 29 |
| » Defeated Yankees (26-13), 7-3 | Yankee Stadium (1-4) | 19-17 | |
| » Starters: Willard Nixon vs Don Larsen | Third | 5½ out |
| Wednesday, May 30 |
| » Lost to Orioles (18-20), 2-1 | Memorial Stadium (0-1) | 19-18 | |
| » Starters: Ike Delock vs Ray Moore | Fourth | 7½ out |
| » Lost to Orioles (19-20), 5-4 | Memorial Stadium (0-2) | 19-19 | Lost 2 |
| » Starters: George Susce vs Hal Brown | Fourth | 7½ out |
| Thursday, May 31 |
| » Defeated Orioles (19-21), 4-1 | Memorial Stadium (1-2) | 20-19 | |
| » Starters: Bob Porterfield vs Bill Wight | Fourth | 7½ out |
| Friday, June 1 |
| » Defeated Athletics (15-25), 5-0 | Fenway Park (12-8) | 21-19 | Won 2 |
| » Starters: Troy Herriage vs Tom Brewer | Fourth | 6½ out |
| Saturday, June 2 |
| » Lost to Athletics (16-25), 11-3 | Fenway Park (12-9) | 21-20 | |
| » Starters: Tom Gorman vs Frank Sullivan | Fourth | 7 out |
| Sunday, June 3 |
| » Lost to Athletics (17-25), 7-6 | Fenway Park (12-10) | 21-21 | Lost 2 |
| » Starters: Art Ditmar vs Willard Nixon | Fourth | 6½ out |
| Former Red Sox Roxy Walters dies in Alameda, CA at the age of 64. |
| Tuesday, June 5 |
| » Lost to Tigers (22-21), 14-11 | Fenway Park (12-11) | 21-22 | Lost 3 |
| » Starters: Virgil Trucks vs Bob Porterfield | Fifth | 6½ out |
| Wednesday, June 6 |
| » Defeated Tigers (22-22), 5-4 | Fenway Park (13-11) | 22-22 | |
| » Starters: Paul Foytack vs Tom Brewer | Fourth | 6½ out |
| Thursday, June 7 |
| » Defeated Tigers (22-23), 6-5 | Fenway Park (14-11) | 23-22 | Won 2 |
| » Starters: Frank Lary vs Frank Sullivan | Fourth | 6½ out |
| Friday, June 8 |
| » Defeated White Sox (22-19), 5-3 | Fenway Park (15-11) | 24-22 | Won 3 |
| » Starters: Bob Keegan vs Willard Nixon | Fourth | 5½ out |
| Saturday, June 9 |
| » Lost to White Sox (23-19), 8-0 | Fenway Park (15-12) | 24-23 | |
| » Starters: Jim Wilson vs Ike Delock | Fourth | 5½ out |
| Sunday, June 10 |
| » Lost to White Sox (24-19), 3-2 | Fenway Park (15-13) | 24-24 | Lost 2 |
| » Starters: Billy Pierce vs George Susce | Fourth | 6½ out |
| Monday, June 11 |
| » Lost to Indians (28-21), 4-1 | Fenway Park (15-14) | 24-25 | Lost 3 |
| » Starters: Cal McLish vs Bob Porterfield | Fourth | 6½ out |
| » Defeated Indians (28-22), 5-1 | Fenway Park (16-14) | 25-25 | |
| » Starters: Mike Garcia vs Tom Brewer | Fourth | 6½ out |
| Tuesday, June 12 |
| » Defeated Indians (28-23), 9-7 | Fenway Park (17-14) | 26-25 | Won 2 |
| » Starters: Early Wynn vs Frank Sullivan | Fourth | 6½ out |
| Wednesday, June 13 |
| » Tied Indians, 8-8 | Fenway Park (17-14) | 26-25 | |
| » Starters: Don Mossi vs Willard Nixon | Fourth | 6 out |
| Thursday, June 14 |
| » Defeated Indians (28-24), 10-9 | Fenway Park (18-14) | 27-25 | Won 3 |
| » Starters: Bob Lemon vs Ike Delock | Fourth | 6 out |
| Friday, June 15 |
| » Lost to Tigers (27-26), 5-2 | Tiger Stadium (1-2) | 27-26 | |
| » Starters: Bob Porterfield vs Frank Lary | Fourth | 7 out |
| Saturday, June 16 |
| » Defeated Tigers (27-27), 6-5 | Tiger Stadium (2-2) | 28-26 | |
| » Starters: Tom Brewer vs Steve Gromek | Third | 7 out |
| Sunday, June 17 |
| » Defeated Tigers (27-28), 13-2 | Tiger Stadium (3-2) | 29-26 | Won 2 |
| » Starters: Frank Sullivan vs Billy Hoeft | Third | 7 out |
| Tuesday, June 19 |
| » Lost to Indians (29-27), 9-7 | Cleveland Stadium (1-2) | 29-27 | |
| » Starters: Ike Delock vs Bob Lemon | Third | 8½ out |
| Wednesday, June 20 |
| » Lost to Indians (30-27), 5-4 | Cleveland Stadium (1-3) | 29-28 | Lost 2 |
| » Starters: Bob Porterfield vs Herb Score | Fourth | 9½ out |
| Thursday, June 21 |
| » Lost to Indians (31-27), 5-0 | Cleveland Stadium (1-4) | 29-29 | Lost 3 |
| » Starters: Tom Brewer vs Early Wynn | Fourth | 10 out |
| Friday, June 22 |
| » Defeated Athletics (24-37), 6-3 | Municipal Stadium (3-1) | 30-29 | |
| » Starters: Frank Sullivan vs Art Ditmar | Fourth | 9 out |
| Saturday, June 23 |
| » Defeated Athletics (24-38), 6-3 | Municipal Stadium (4-1) | 31-29 | Won 2 |
| » Starters: Mel Parnell vs Tom Gorman | Fourth | 8 out |
| Sunday, June 24 |
| » Lost to Athletics (25-38), 5-2 | Municipal Stadium (4-2) | 31-30 | |
| » Starters: Dave Sisler vs Alex Kellner | Fourth | 7½ out |
| Tuesday, June 26 |
| » Lost to White Sox (37-22), 4-1 | Comiskey Park I (2-1) | 31-31 | Lost 2 |
| » Starters: Tom Brewer vs Jack Harshman | Fourth | 9 out |
| Wednesday, June 27 |
| » Defeated White Sox (37-23), 11-9 | Comiskey Park I (3-1) | 32-31 | |
| » Starters: Frank Sullivan vs Dick Donovan | Fourth | 9 out |
| Friday, June 29 |
| » Defeated Orioles (31-36), 7-6 | Memorial Stadium (2-2) | 33-31 | Won 2 |
| » Starters: Mel Parnell vs Ray Moore | Fourth | 9 out |
| Saturday, June 30 |
| » Defeated Orioles (31-37), 4-2 | Memorial Stadium (3-2) | 34-31 | Won 3 |
| » Starters: Willard Nixon vs Billy Loes | Fourth | 7½ out |
| » Defeated Orioles (31-38), 6-3 | Memorial Stadium (4-2) | 35-31 | Won 4 |
| » Starters: Tom Brewer vs Don Ferrarese | Fourth | 7½ out |
| Sunday, July 1 |
| » Lost to Orioles (32-38), 5-3 | Memorial Stadium (4-3) | 35-32 | |
| » Starters: Bob Porterfield vs Connie Johnson | Fourth | 9 out |
| Monday, July 2 |
| » Defeated Senators (29-46), 3-2 | Griffith Stadium (2-2) | 36-32 | |
| » Starters: Frank Sullivan vs Bob Wiesler | Fourth | 8½ out |
| Tuesday, July 3 |
| » Lost to Senators (30-46), 6-5 | Griffith Stadium (2-3) | 36-33 | |
| » Starters: Dave Sisler vs Dean Stone | Fourth | 9½ out |
| Wednesday, July 4 |
| » Defeated Yankees (47-26), 7-6 | Fenway Park (19-14) | 37-33 | |
| » Starters: Johnny Kucks vs Willard Nixon | Fourth | 9½ out |
| » Lost to Yankees (48-26), 9-4 | Fenway Park (19-15) | 37-34 | |
| » Starters: Don Larsen vs Mel Parnell | Fourth | 9½ out |
| Thursday, July 5 |
| » Lost to Yankees (49-26), 6-1 | Fenway Park (19-16) | 37-35 | Lost 2 |
| » Starters: Whitey Ford vs Bob Porterfield | Fourth | 10½ out |
| Saturday, July 7 |
| » Defeated Orioles (33-41), 4-3 | Fenway Park (20-16) | 38-35 | |
| » Starters: Billy Loes vs Tom Brewer | Fourth | 11 out |
| Sunday, July 8 |
| » Defeated Orioles (33-42), 9-0 | Fenway Park (21-16) | 39-35 | Won 2 |
| » Starters: Ray Moore vs Frank Sullivan | Fourth | 10½ out |
| » Defeated Orioles (33-43), 8-4 | Fenway Park (22-16) | 40-35 | Won 3 |
| » Starters: Connie Johnson vs Willard Nixon | Fourth | 10½ out |
| Thursday, July 12 |
| » Defeated White Sox (43-31), 3-1 | Fenway Park (23-16) | 41-35 | Won 4 |
| » Starters: Jack Harshman vs Frank Sullivan | Fourth | 10½ out |
| Friday, July 13 |
| » Defeated White Sox (43-32), 5-4 | Fenway Park (24-16) | 42-35 | Won 5 |
| » Starters: Jim Wilson vs Tom Brewer | Fourth | 10½ out |
| Saturday, July 14 |
| » Defeated White Sox (43-33), 4-0 | Fenway Park (25-16) | 43-35 | Won 6 |
| » Starters: Jim McDonald vs Mel Parnell | Fourth | 10½ out |
| Sunday, July 15 |
| » Lost to Indians (45-34), 10-7 | Fenway Park (25-17) | 43-36 | |
| » Starters: Hank Aguirre vs Willard Nixon | Fourth | 11½ out |
| » Defeated Indians (45-35), 3-1 | Fenway Park (26-17) | 44-36 | |
| » Starters: Mike Garcia vs Dave Sisler | Fourth | 11½ out |
| Monday, July 16 |
| » Lost to Indians (46-35), 7-3 | Fenway Park (26-18) | 44-37 | |
| » Starters: Bob Lemon vs Frank Sullivan | Fourth | 12 out |
| Tuesday, July 17 |
| » Defeated Athletics (30-52), 10-0 | Fenway Park (27-18) | 45-37 | |
| » Starters: Art Ditmar vs Tom Brewer | Third | 11½ out |
| » Defeated Athletics (30-53), 1-0 | Fenway Park (28-18) | 46-37 | Won 2 |
| » Starters: Tom Gorman vs Bob Porterfield | Third | 11½ out |
| Wednesday, July 18 |
| » Defeated Athletics (30-54), 7-4 | Fenway Park (29-18) | 47-37 | Won 3 |
| » Starters: Troy Herriage vs Mel Parnell | Third | 10 out |
| Thursday, July 19 |
| » Lost to Athletics (31-54), 8-4 | Fenway Park (29-19) | 47-38 | |
| » Starters: Wally Burnette vs Dave Sisler | Third | 11 out |
| Friday, July 20 |
| » Lost to Tigers (39-47), 9-6 | Fenway Park (29-20) | 47-39 | Lost 2 |
| » Starters: Virgil Trucks vs Willard Nixon | Third | 12 out |
| Saturday, July 21 |
| » Defeated Tigers (39-48), 9-3 | Fenway Park (30-20) | 48-39 | |
| » Starters: Billy Hoeft vs Frank Sullivan | Third | 11½ out |
| Sunday, July 22 |
| » Defeated Tigers (39-49), 8-6 | Fenway Park (31-20) | 49-39 | Won 2 |
| » Starters: Frank Lary vs Tom Brewer | Third | 11 out |
| Tuesday, July 24 |
| » Defeated Athletics (33-57), 3-2 | Municipal Stadium (5-2) | 50-39 | Won 3 |
| » Starters: Mel Parnell vs Wally Burnette | Third | 10 out |
| Wednesday, July 25 |
| » Lost to Athletics (34-57), 9-6 | Municipal Stadium (5-3) | 50-40 | |
| » Starters: Bob Porterfield vs Art Ditmar | Third | 11 out |
| Thursday, July 26 |
| » Defeated Athletics (34-58), 5-3 | Municipal Stadium (6-3) | 51-40 | |
| » Starters: Frank Sullivan vs Troy Herriage | Third | 11 out |
| Friday, July 27 |
| » Defeated White Sox (46-43), 4-3 | Comiskey Park I (4-1) | 52-40 | Won 2 |
| » Starters: Tom Brewer vs Jim Wilson | Third | 11 out |
| Saturday, July 28 |
| » Defeated White Sox (46-44), 13-1 | Comiskey Park I (5-1) | 53-40 | Won 3 |
| » Starters: Willard Nixon vs Jim McDonald | Third | 11 out |
| Sunday, July 29 |
| » Lost to White Sox (47-44), 11-2 | Comiskey Park I (5-2) | 53-41 | |
| » Starters: Dave Sisler vs Billy Pierce | Third | 12½ out |
| » Lost to White Sox (48-44), 6-3 | Comiskey Park I (5-3) | 53-42 | Lost 2 |
| » Starters: Mel Parnell vs Jack Harshman | Third | 12½ out |
| Monday, July 30 |
| » Lost to Tigers (44-53), 4-1 | Tiger Stadium (3-3) | 53-43 | Lost 3 |
| » Starters: Frank Sullivan vs Virgil Trucks | Third | 13½ out |
| Tuesday, July 31 |
| » Lost to Tigers (45-53), 6-4 | Tiger Stadium (3-4) | 53-44 | Lost 4 |
| » Starters: Bob Porterfield vs Frank Lary | Third | 13½ out |
| Wednesday, August 1 |
| » Defeated Tigers (45-54), 5-4 | Tiger Stadium (4-4) | 54-44 | |
| » Starters: Tom Brewer vs Paul Foytack | Third | 12½ out |
| Thursday, August 2 |
| » Defeated Tigers (45-55), 18-3 | Tiger Stadium (5-4) | 55-44 | Won 2 |
| » Starters: Willard Nixon vs Bob Miller | Third | 11½ out |
| Friday, August 3 |
| » Defeated Indians (59-40), 7-1 | Cleveland Stadium (2-4) | 56-44 | Won 3 |
| » Starters: Mel Parnell vs Mike Garcia | Third | 10½ out |
| Saturday, August 4 |
| » Defeated Indians (59-41), 6-5 | Cleveland Stadium (3-4) | 57-44 | Won 4 |
| » Starters: Frank Sullivan vs Early Wynn | Third | 9½ out |
| Sunday, August 5 |
| » Defeated Indians (59-42), 2-1 | Cleveland Stadium (4-4) | 58-44 | Won 5 |
| » Starters: Dave Sisler vs Bob Lemon | Third | 8½ out |
| Monday, August 6 |
| » Lost to Yankees (68-36), 4-3 | Fenway Park (31-21) | 58-45 | |
| » Starters: Ralph Terry vs Tom Brewer | Third | 9½ out |
| » Major-league debuts: Ralph Terry (Yankees) |
| Tuesday, August 7 |
| » Defeated Yankees (68-37), 1-0 | Fenway Park (32-21) | 59-45 | |
| » Starters: Don Larsen vs Willard Nixon | Third | 8½ out |
| Wednesday, August 8 |
| » Defeated Orioles (47-58), 7-2 | Fenway Park (33-21) | 60-45 | Won 2 |
| » Starters: Connie Johnson vs Mel Parnell | Third | 8½ out |
| Thursday, August 9 |
| » Defeated Orioles (47-59), 3-1 | Fenway Park (34-21) | 61-45 | Won 3 |
| » Starters: Mike Fornieles vs Frank Sullivan | Second | 8½ out |
| Friday, August 10 |
| » Defeated Senators (43-64), 3-2 | Griffith Stadium (3-3) | 62-45 | Won 4 |
| » Starters: Tom Brewer vs Chuck Stobbs | Second | 8½ out |
| Saturday, August 11 |
| » Lost to Senators (44-64), 6-1 | Griffith Stadium (3-4) | 62-46 | |
| » Starters: Dave Sisler vs Pedro Ramos | Third | 8½ out |
| Sunday, August 12 |
| » Lost to Senators (45-64), 8-2 | Griffith Stadium (3-5) | 62-47 | Lost 2 |
| » Starters: Willard Nixon vs Dean Stone | Third | 10 out |
| Tuesday, August 14 |
| » Lost to Yankees (74-38), 12-2 | Yankee Stadium (1-5) | 62-48 | Lost 3 |
| » Starters: Mel Parnell vs Johnny Kucks | Third | 11 out |
| Wednesday, August 15 |
| » Lost to Yankees (75-38), 6-4 | Yankee Stadium (1-6) | 62-49 | Lost 4 |
| » Starters: Tom Brewer vs Whitey Ford | Third | 12 out |
| Thursday, August 16 |
| » Defeated Yankees (75-39), 2-1 | Yankee Stadium (2-6) | 63-49 | |
| » Starters: Willard Nixon vs Don Larsen | Third | 11 out |
| Friday, August 17 |
| » Lost to Senators (46-66), 6-5 | Fenway Park (34-22) | 63-50 | |
| » Starters: Pedro Ramos vs Frank Sullivan | Third | 11 out |
| Saturday, August 18 |
| » Lost to Senators (47-66), 9-7 | Fenway Park (34-23) | 63-51 | Lost 2 |
| » Starters: Dean Stone vs George Susce | Third | 12½ out |
| Sunday, August 19 |
| » Lost to Senators (48-66), 7-5 | Fenway Park (34-24) | 63-52 | Lost 3 |
| » Starters: Chuck Stobbs vs Tom Brewer | Fourth | 13 out |
| » Lost to Senators (49-66), 11-10 | Fenway Park (34-25) | 63-53 | Lost 4 |
| » Starters: Camilo Pascual vs Mel Parnell | Fourth | 13 out |
| Tuesday, August 21 |
| Future Red Sox John Henry Johnson is born in Houston, TX. |
| Wednesday, August 22 |
| » Lost to White Sox (63-51), 6-3 | Fenway Park (34-26) | 63-54 | Lost 5 |
| » Starters: Billy Pierce vs Willard Nixon | Fourth | 13 out |
| » Defeated White Sox (63-52), 7-6 | Fenway Park (35-26) | 64-54 | |
| » Starters: Jim Wilson vs Frank Sullivan | Fourth | 13 out |
| Thursday, August 23 |
| » Defeated Indians (68-50), 2-1 | Fenway Park (36-26) | 65-54 | Won 2 |
| » Starters: Bob Lemon vs Mel Parnell | Fourth | 11½ out |
| Friday, August 24 |
| » Lost to Indians (69-50), 5-3 | Fenway Park (36-27) | 65-55 | |
| » Starters: Mike Garcia vs Tom Brewer | Fourth | 12½ out |
| Saturday, August 25 |
| » Defeated Indians (69-51), 9-6 | Fenway Park (37-27) | 66-55 | |
| » Starters: Herb Score vs Dave Sisler | Fourth | 11½ out |
| Sunday, August 26 |
| » Defeated Athletics (40-82), 2-1 | Fenway Park (38-27) | 67-55 | Won 2 |
| » Starters: Tom Gorman vs Willard Nixon | Fourth | 11½ out |
| » Lost to Athletics (41-82), 7-6 | Fenway Park (38-28) | 67-56 | |
| » Starters: Wally Burnette vs Frank Sullivan | Fourth | 11½ out |
| Tuesday, August 28 |
| » Lost to Tigers (61-64), 6-3 | Fenway Park (38-29) | 67-57 | Lost 2 |
| » Starters: Frank Lary vs Mel Parnell | Fourth | 12½ out |
| Wednesday, August 29 |
| » Defeated Tigers (61-65), 4-2 | Fenway Park (39-29) | 68-57 | |
| » Starters: Billy Hoeft vs Tom Brewer | Fourth | 12½ out |
| Friday, August 31 |
| » Lost to Orioles (57-69), 13-6 | Fenway Park (39-30) | 68-58 | |
| » Starters: Connie Johnson vs Willard Nixon | Fourth | 13½ out |
| Saturday, September 1 |
| » Defeated Orioles (57-70), 4-2 | Fenway Park (40-30) | 69-58 | |
| » Starters: Hal Brown vs Frank Sullivan | Fourth | 12½ out |
| Sunday, September 2 |
| » Lost to Orioles (58-70), 11-10 | Fenway Park (40-31) | 69-59 | |
| » Starters: Ray Moore vs Bob Porterfield | Fourth | 12½ out |
| Monday, September 3 |
| » Defeated Senators (54-75), 7-5 | Griffith Stadium (4-5) | 70-59 | |
| » Starters: Mel Parnell vs Hal Griggs | Fourth | 12½ out |
| » Defeated Senators (54-76), 16-0 | Griffith Stadium (5-5) | 71-59 | Won 2 |
| » Starters: Tom Brewer vs Bob Wiesler | Fourth | 12½ out |
| Tuesday, September 4 |
| » Defeated Senators (54-77), 7-6 | Griffith Stadium (6-5) | 72-59 | Won 3 |
| » Starters: Dave Sisler vs Camilo Pascual | Fourth | 12 out |
| Wednesday, September 5 |
| » Lost to Yankees (86-48), 5-3 | Fenway Park (40-32) | 72-60 | |
| » Starters: Whitey Ford vs Willard Nixon | Fourth | 13 out |
| Friday, September 7 |
| » Defeated Orioles (58-75), 7-5 | Memorial Stadium (5-3) | 73-60 | |
| » Starters: Mel Parnell vs Mike Fornieles | Fourth | 12½ out |
| » Lost to Orioles (59-75), 5-0 | Memorial Stadium (5-4) | 73-61 | |
| » Starters: Frank Sullivan vs Hal Brown | Fourth | 12½ out |
| Saturday, September 8 |
| » Defeated Orioles (59-76), 6-1 | Memorial Stadium (6-4) | 74-61 | |
| » Starters: Tom Brewer vs Billy Loes | Third | 12½ out |
| » Major-league debuts: Ron Moeller (Orioles) |
| Sunday, September 9 |
| » Defeated Orioles (59-77), 3-2 | Memorial Stadium (7-4) | 75-61 | Won 2 |
| » Starters: Dave Sisler vs Connie Johnson | Third | 12½ out |
| Tuesday, September 11 |
| » Defeated White Sox (76-60), 5-3 | Comiskey Park I (6-3) | 76-61 | Won 3 |
| » Starters: Willard Nixon vs Bob Keegan | Fourth | 12½ out |
| Wednesday, September 12 |
| » Defeated White Sox (76-61), 4-1 | Comiskey Park I (7-3) | 77-61 | Won 4 |
| » Starters: Frank Sullivan vs Jack Harshman | Third | 11½ out |
| Thursday, September 13 |
| » Lost to White Sox (77-61), 4-3 | Comiskey Park I (7-4) | 77-62 | |
| » Starters: Tom Brewer vs Billy Pierce | Fourth | 12½ out |
| Friday, September 14 |
| » Lost to Indians (79-60), 10-2 | Cleveland Stadium (4-5) | 77-63 | Lost 2 |
| » Starters: Mel Parnell vs Herb Score | Fourth | 13 out |
| » Defeated Indians (79-61), 4-3 | Cleveland Stadium (5-5) | 78-63 | |
| » Starters: Dave Sisler vs Mike Garcia | Fourth | 13 out |
| Saturday, September 15 |
| » Defeated Indians (79-62), 5-3 | Cleveland Stadium (6-5) | 79-63 | Won 2 |
| » Starters: Rudy Minarcin vs Bob Feller | Fourth | 12 out |
| Sunday, September 16 |
| » Lost to Tigers (74-68), 5-4 | Tiger Stadium (5-5) | 79-64 | |
| » Starters: Frank Sullivan vs Billy Hoeft | Fourth | 13 out |
| » Lost to Tigers (75-68), 8-4 | Tiger Stadium (5-6) | 79-65 | Lost 2 |
| » Starters: Willard Nixon vs Gene Host | Fourth | 13 out |
| Tuesday, September 18 |
| » Lost to Athletics (47-96), 6-5 | Municipal Stadium (6-4) | 79-66 | Lost 3 |
| » Starters: Tom Brewer vs Tom Gorman | Fourth | 14 out |
| Wednesday, September 19 |
| » Lost to Athletics (48-96), 8-1 | Municipal Stadium (6-5) | 79-67 | Lost 4 |
| » Starters: Dave Sisler vs Wally Burnette | Fourth | 14½ out |
| Friday, September 21 |
| » Defeated Yankees (93-53), 13-7 | Fenway Park (41-32) | 80-67 | |
| » Starters: Bob Turley vs Frank Sullivan | Fourth | 13½ out |
| » Major-league debuts: Jim Coates (Yankees) |
| Saturday, September 22 |
| » Lost to Yankees (94-53), 2-1 | Fenway Park (41-33) | 80-68 | |
| » Starters: Don Larsen vs Bob Porterfield | Fourth | 14½ out |
| Former Red Sox Jesse Tannehill dies in Dayton, KY at the age of 83. |
| Sunday, September 23 |
| » Lost to Yankees (95-53), 7-4 | Fenway Park (41-34) | 80-69 | Lost 2 |
| » Starters: Rip Coleman vs Tom Brewer | Fourth | 15½ out |
| Tuesday, September 25 |
| » Defeated Senators (58-92), 10-4 | Fenway Park (42-34) | 81-69 | |
| » Starters: Pedro Ramos vs Dave Sisler | Fourth | 15 out |
| Wednesday, September 26 |
| » Defeated Senators (58-93), 8-4 | Fenway Park (43-34) | 82-69 | Won 2 |
| » Starters: Ted Abernathy vs Frank Sullivan | Fourth | 14 out |
| Friday, September 28 |
| » Lost to Yankees (97-55), 7-2 | Yankee Stadium (2-7) | 82-70 | |
| » Starters: Bob Porterfield vs Don Larsen | Fourth | 15 out |
| Saturday, September 29 |
| » Defeated Yankees (97-56), 7-5 | Yankee Stadium (3-7) | 83-70 | |
| » Starters: Mel Parnell vs Tommy Byrne | Fourth | 14 out |
| Sunday, September 30 |
| » Defeated Yankees (97-57), 7-4 | Yankee Stadium (4-7) | 84-70 | Won 2 |
| » Starters: Dave Sisler vs Bob Turley | Fourth | 13 out |
| Saturday, October 13 |
| Former Red Sox George Dumont dies in Minneapolis, MN at the age of 61. |
| Thursday, November 29 |
| Future Red Sox Joe Price is born in Inglewood, CA. |
| Wednesday, December 12 |
| Future Red Sox Steve Farr is born in LaPlata, MD. |
| Saturday, December 22 |
| Future Red Sox Dave Schmidt is born in Mesa, AZ. |
Game information provided by Retrosheet (www.retrosheet.org) |