| Tuesday, January 25 |
| Former Athletic Harry Barton dies in Upland, PA at the age of 81. |
| Wednesday, January 26 |
| Future Athletic Brian Doyle is born in Glasgow, KY. |
| Saturday, February 5 |
| Future Athletic Mike Heath is born in Tampa, FL. |
| Sunday, March 27 |
| Former Athletic Frank Roth dies in Burlington, WI at the age of 77. |
| Monday, April 11 |
| » Major-league debuts: Ernie Oravetz and Pedro Ramos (Senators) Don Ferrarese and Don Leppert (Orioles) |
| Tuesday, April 12 |
| » Defeated Tigers (0-1), 6-2 | Municipal Stadium (1-0) | 1-0 | |
| » Starters: Ned Garver vs Alex Kellner | First | -- |
| » Major-league debuts: Harry Malmberg (Tigers) |
| Wednesday, April 13 |
| » Lost to Tigers (1-1), 10-2 | Municipal Stadium (1-1) | 1-1 | |
| » Starters: Steve Gromek vs Arnie Portocarrero | Second | ½ out |
| Thursday, April 14 |
| » Lost to White Sox (1-1), 7-1 | Comiskey Park I (0-1) | 1-2 | Lost 2 |
| » Starters: Bobby Shantz vs Sandy Consuegra | Third | 1½ out |
| Friday, April 15 |
| » Major-league debuts: Herb Score (Indians) |
| Saturday, April 16 |
| » Lost to Tigers (2-3), 8-3 | Tiger Stadium (0-1) | 1-3 | Lost 3 |
| » Starters: Arnie Portocarrero vs Ned Garver | Fifth | 2 out |
| Sunday, April 17 |
| » Lost to Tigers (3-3), 16-0 | Tiger Stadium (0-2) | 1-4 | Lost 4 |
| » Starters: Johnny Gray vs Steve Gromek | Sixth | 3½ out |
| Monday, April 18 |
| » Lost to Indians (5-2), 11-9 | Municipal Stadium (1-2) | 1-5 | Lost 5 |
| » Starters: Mike Garcia vs Alex Kellner | Seventh | 4 out |
| Tuesday, April 19 |
| » Defeated Indians (5-3), 8-7 | Municipal Stadium (2-2) | 2-5 | |
| » Starters: Herb Score vs Cloyd Boyer | Seventh | 3½ out |
| Thursday, April 21 |
| » Major-league debuts: Duke Maas (Tigers) |
| Friday, April 22 |
| » Lost to White Sox (5-2), 5-3 | Municipal Stadium (2-3) | 2-6 | |
| » Starters: Virgil Trucks vs Arnie Portocarrero | Fifth | 3½ out |
| Saturday, April 23 |
| » Lost to White Sox (6-2), 29-6 | Municipal Stadium (2-4) | 2-7 | Lost 2 |
| » Starters: Jack Harshman vs Bobby Shantz | Sixth | 4½ out |
| Sunday, April 24 |
| » Defeated White Sox (6-3), 5-0 | Municipal Stadium (3-4) | 3-7 | |
| » Starters: Dick Donovan vs Alex Kellner | Fifth | 3½ out |
| Tuesday, April 26 |
| » Defeated Red Sox (7-5), 8-7 | Municipal Stadium (4-4) | 4-7 | Won 2 |
| » Starters: Tom Brewer vs Arnie Portocarrero | Sixth | 3½ out |
| Wednesday, April 27 |
| » Defeated Red Sox (7-6), 6-2 | Municipal Stadium (5-4) | 5-7 | Won 3 |
| » Starters: Frank Sullivan vs Cloyd Boyer | Fifth | 2½ out |
| Thursday, April 28 |
| » Lost to Yankees (9-5), 11-4 | Municipal Stadium (5-5) | 5-8 | |
| » Starters: Bob Grim vs Johnny Gray | Fifth | 3½ out |
| Friday, April 29 |
| » Defeated Yankees (9-6), 6-0 | Municipal Stadium (6-5) | 6-8 | |
| » Starters: Johnny Kucks vs Bobby Shantz | Sixth | 3 out |
| Sunday, May 1 |
| » Defeated Senators (5-11), 16-10 | Municipal Stadium (7-5) | 7-8 | Won 2 |
| » Starters: Mickey McDermott vs Art Ditmar | Third | 3 out |
| Monday, May 2 |
| » Lost to Senators (6-11), 12-1 | Municipal Stadium (7-6) | 7-9 | |
| » Starters: Johnny Schmitz vs Cloyd Boyer | Fifth | 4 out |
| Tuesday, May 3 |
| » Defeated Orioles (5-14), 4-3 | Municipal Stadium (8-6) | 8-9 | |
| » Starters: Erv Palica vs Art Ceccarelli | Fifth | 4 out |
| Wednesday, May 4 |
| » Defeated Orioles (5-15), 6-5 | Municipal Stadium (9-6) | 9-9 | Won 2 |
| » Starters: Harry Byrd vs Vic Raschi | Fifth | 3 out |
| Friday, May 6 |
| » Lost to Indians (14-7), 4-1 | Cleveland Stadium (0-1) | 9-10 | |
| » Starters: Alex Kellner vs Herb Score | Fifth | 4 out |
| Saturday, May 7 |
| » Lost to Indians (15-7), 9-3 | Cleveland Stadium (0-2) | 9-11 | Lost 2 |
| » Starters: Bobby Shantz vs Early Wynn | Fifth | 5 out |
| Sunday, May 8 |
| » Lost to Indians (16-7), 9-6 | Cleveland Stadium (0-3) | 9-12 | Lost 3 |
| » Starters: Cloyd Boyer vs Bob Feller | Fourth | 7 out |
| » Lost to Indians (17-7), 2-1 | Cleveland Stadium (0-4) | 9-13 | Lost 4 |
| » Starters: Art Ceccarelli vs Mike Garcia | Fourth | 7 out |
| Tuesday, May 10 |
| » Lost to Orioles (8-17), 11-1 | Memorial Stadium (0-1) | 9-14 | Lost 5 |
| » Starters: Lou Sleater vs Harry Byrd | Sixth | 8 out |
| Wednesday, May 11 |
| » Defeated Orioles (8-18), 2-0 | Memorial Stadium (1-1) | 10-14 | |
| » Starters: Alex Kellner vs Lou Kretlow | Fifth | 8 out |
| Thursday, May 12 |
| » Lost to Red Sox (11-17), 12-7 | Fenway Park (0-1) | 10-15 | |
| » Starters: Vic Raschi vs Ike Delock | Sixth | 8 out |
| Friday, May 13 |
| » Lost to Red Sox (12-17), 4-3 | Fenway Park (0-2) | 10-16 | Lost 2 |
| » Starters: Art Ceccarelli vs Willard Nixon | Seventh | 8½ out |
| Saturday, May 14 |
| » Lost to Red Sox (13-17), 3-1 | Fenway Park (0-3) | 10-17 | Lost 3 |
| » Starters: Art Ditmar vs Leo Kiely | Seventh | 9 out |
| Sunday, May 15 |
| » Defeated Yankees (16-11), 4-3 | Yankee Stadium (1-0) | 11-17 | |
| » Starters: Bobby Shantz vs Ed Lopat | Seventh | 9 out |
| » Lost to Yankees (17-11), 8-4 | Yankee Stadium (1-1) | 11-18 | |
| » Starters: Ray Herbert vs Bob Turley | Seventh | 9 out |
| Tuesday, May 17 |
| » Defeated Senators (11-18), 1-0 | Griffith Stadium (1-0) | 12-18 | |
| » Starters: Alex Kellner vs Mickey McDermott | Sixth | 8 out |
| Wednesday, May 18 |
| » Lost to Senators (12-18), 7-2 | Griffith Stadium (1-1) | 12-19 | |
| » Starters: Art Ceccarelli vs Dean Stone | Seventh | 9 out |
| Friday, May 20 |
| » Defeated White Sox (18-12), 1-0 | Comiskey Park I (1-1) | 13-19 | |
| » Starters: Art Ditmar vs Sandy Consuegra | Seventh | 8 out |
| Saturday, May 21 |
| » Lost to White Sox (19-12), 7-4 | Comiskey Park I (1-2) | 13-20 | |
| » Starters: Bobby Shantz vs Dick Donovan | Seventh | 8½ out |
| Sunday, May 22 |
| » Defeated White Sox (19-13), 7-2 | Comiskey Park I (2-2) | 14-20 | |
| » Starters: Alex Kellner vs Bob Keegan | Seventh | 9½ out |
| » Lost to White Sox (20-13), 10-6 | Comiskey Park I (2-3) | 14-21 | |
| » Starters: Art Ceccarelli vs Mike Fornieles | Seventh | 9½ out |
| Tuesday, May 24 |
| » Lost to Tigers (20-16), 9-6 | Municipal Stadium (9-7) | 14-22 | Lost 2 |
| » Starters: Steve Gromek vs Art Ditmar | Seventh | 9½ out |
| Wednesday, May 25 |
| » Lost to Tigers (21-16), 8-2 | Municipal Stadium (9-8) | 14-23 | Lost 3 |
| » Starters: Frank Lary vs Ray Herbert | Seventh | 10½ out |
| Saturday, May 28 |
| » Lost to Indians (24-14), 7-2 | Municipal Stadium (9-9) | 14-24 | Lost 4 |
| » Starters: Early Wynn vs Alex Kellner | Seventh | 13 out |
| Sunday, May 29 |
| » Lost to Indians (25-14), 4-2 | Municipal Stadium (9-10) | 14-25 | Lost 5 |
| » Starters: Herb Score vs Bobby Shantz | Seventh | 14 out |
| Monday, May 30 |
| » Defeated Tigers (22-19), 8-6 | Tiger Stadium (1-2) | 15-25 | |
| » Starters: Art Ditmar vs Frank Lary | Seventh | 13 out |
| » Defeated Tigers (22-20), 5-4 | Tiger Stadium (2-2) | 16-25 | Won 2 |
| » Starters: Vic Raschi vs Duke Maas | Seventh | 13 out |
| Wednesday, June 1 |
| » Lost to Yankees (31-13), 3-1 | Municipal Stadium (9-11) | 16-26 | |
| » Starters: Johnny Kucks vs Ray Herbert | Seventh | 15 out |
| » Lost to Yankees (32-13), 6-1 | Municipal Stadium (9-12) | 16-27 | Lost 2 |
| » Starters: Whitey Ford vs Alex Kellner | Seventh | 15 out |
| Thursday, June 2 |
| » Lost to Yankees (33-13), 12-6 | Municipal Stadium (9-13) | 16-28 | Lost 3 |
| » Starters: Bob Grim vs Art Ceccarelli | Seventh | 16 out |
| Friday, June 3 |
| » Defeated Red Sox (19-29), 4-3 | Municipal Stadium (10-13) | 17-28 | |
| » Starters: Ike Delock vs Bobby Shantz | Seventh | 15 out |
| Saturday, June 4 |
| » Lost to Red Sox (20-29), 5-1 | Municipal Stadium (10-14) | 17-29 | |
| » Starters: Frank Sullivan vs Art Ditmar | Seventh | 16 out |
| Sunday, June 5 |
| » Defeated Red Sox (20-30), 5-4 | Municipal Stadium (11-14) | 18-29 | |
| » Starters: Willard Nixon vs Vic Raschi | Seventh | 16 out |
| » Lost to Red Sox (21-30), 4-3 | Municipal Stadium (11-15) | 18-30 | |
| » Starters: Tom Brewer vs Ray Herbert | Seventh | 16 out |
| Tuesday, June 7 |
| » Lost to Senators (21-27), 3-2 | Municipal Stadium (11-16) | 18-31 | Lost 2 |
| » Starters: Camilo Pascual vs Alex Kellner | Seventh | 17 out |
| » Lost to Senators (22-27), 7-3 | Municipal Stadium (11-17) | 18-32 | Lost 3 |
| » Starters: Mickey McDermott vs Art Ceccarelli | Seventh | 17 out |
| Wednesday, June 8 |
| » Defeated Senators (22-28), 3-2 | Municipal Stadium (12-17) | 19-32 | |
| » Starters: Bob Porterfield vs Cloyd Boyer | Seventh | 16 out |
| Thursday, June 9 |
| » Defeated Senators (22-29), 4-2 | Municipal Stadium (13-17) | 20-32 | Won 2 |
| » Starters: Chuck Stobbs vs Art Ditmar | Seventh | 16 out |
| Friday, June 10 |
| » Lost to Orioles (17-36), 3-0 | Municipal Stadium (13-18) | 20-33 | |
| » Starters: Jim Wilson vs Ray Herbert | Seventh | 17 out |
| Saturday, June 11 |
| » Defeated Orioles (17-37), 2-1 | Municipal Stadium (14-18) | 21-33 | |
| » Starters: Duane Pillette vs Vic Raschi | Seventh | 16 out |
| Sunday, June 12 |
| » Lost to Orioles (18-37), 7-2 | Municipal Stadium (14-19) | 21-34 | |
| » Starters: Don Johnson vs Arnie Portocarrero | Seventh | 15 out |
| » Defeated Orioles (18-38), 3-0 | Municipal Stadium (15-19) | 22-34 | |
| » Starters: Erv Palica vs Art Ceccarelli | Seventh | 15 out |
| Tuesday, June 14 |
| » Lost to Red Sox (26-31), 12-4 | Fenway Park (0-4) | 22-35 | |
| » Starters: Art Ditmar vs Frank Sullivan | Seventh | 16 out |
| Wednesday, June 15 |
| » Lost to Red Sox (27-31), 9-6 | Fenway Park (0-5) | 22-36 | Lost 2 |
| » Starters: Ray Herbert vs Mel Parnell | Seventh | 16 out |
| Thursday, June 16 |
| » Lost to Red Sox (28-31), 7-6 | Fenway Park (0-6) | 22-37 | Lost 3 |
| » Starters: Cloyd Boyer vs Willard Nixon | Seventh | 17 out |
| Friday, June 17 |
| » Defeated Senators (23-36), 4-2 | Griffith Stadium (2-1) | 23-37 | |
| » Starters: Arnie Portocarrero vs Bob Porterfield | Seventh | 16 out |
| Saturday, June 18 |
| » Defeated Senators (23-37), 9-4 | Griffith Stadium (3-1) | 24-37 | Won 2 |
| » Starters: Vic Raschi vs Camilo Pascual | Sixth | 15 out |
| Tuesday, June 21 |
| » Lost to Yankees (43-23), 6-2 | Yankee Stadium (1-2) | 24-38 | |
| » Starters: Alex Kellner vs Tommy Byrne | Sixth | 17 out |
| Wednesday, June 22 |
| » Lost to Yankees (44-23), 6-1 | Yankee Stadium (1-3) | 24-39 | Lost 2 |
| » Starters: Art Ditmar vs Whitey Ford | Sixth | 18 out |
| Former Athletic Frankie Hayes dies in Point Pleasant, NJ at the age of 41. |
| Thursday, June 23 |
| » Lost to Yankees (45-23), 4-0 | Yankee Stadium (1-4) | 24-40 | Lost 3 |
| » Starters: Bobby Shantz vs Bob Turley | Sixth | 19 out |
| Friday, June 24 |
| » Defeated Orioles (20-46), 2-0 | Memorial Stadium (2-1) | 25-40 | |
| » Starters: Arnie Portocarrero vs Saul Rogovin | Sixth | 19 out |
| Saturday, June 25 |
| » Tied Orioles, 3-3 | Memorial Stadium (2-1) | 25-40 | |
| » Starters: Vic Raschi vs Erv Palica | Sixth | 19½ out |
| Sunday, June 26 |
| » Defeated Orioles (20-47), 1-0 | Memorial Stadium (3-1) | 26-40 | Won 2 |
| » Starters: Alex Kellner vs Jim Wilson | Sixth | 18½ out |
| » Defeated Orioles (20-48), 5-2 | Memorial Stadium (4-1) | 27-40 | Won 3 |
| » Starters: Ray Herbert vs Don Johnson | Sixth | 18½ out |
| Tuesday, June 28 |
| » Lost to Indians (42-29), 7-5 | Cleveland Stadium (0-5) | 27-41 | |
| » Starters: Art Ditmar vs Mike Garcia | Sixth | 19 out |
| Wednesday, June 29 |
| » Defeated Indians (42-30), 12-4 | Cleveland Stadium (1-5) | 28-41 | |
| » Starters: Bobby Shantz vs Bob Feller | Sixth | 19½ out |
| Friday, July 1 |
| » Defeated Tigers (38-32), 3-2 | Municipal Stadium (16-19) | 29-41 | Won 2 |
| » Starters: Babe Birrer vs Cloyd Boyer | Sixth | 19 out |
| » Defeated Tigers (38-33), 7-5 | Municipal Stadium (17-19) | 30-41 | Won 3 |
| » Starters: Ned Garver vs Ray Herbert | Sixth | 19 out |
| Saturday, July 2 |
| » Defeated Tigers (38-34), 11-10 | Municipal Stadium (18-19) | 31-41 | Won 4 |
| » Starters: Frank Lary vs Arnie Portocarrero | Sixth | 19 out |
| Sunday, July 3 |
| » Defeated Tigers (38-35), 9-8 | Municipal Stadium (19-19) | 32-41 | Won 5 |
| » Starters: Duke Maas vs Vic Raschi | Sixth | 18 out |
| Monday, July 4 |
| » Lost to White Sox (44-29), 8-3 | Municipal Stadium (19-20) | 32-42 | |
| » Starters: Connie Johnson vs Alex Kellner | Sixth | 17 out |
| » Defeated White Sox (44-30), 4-3 | Municipal Stadium (20-20) | 33-42 | |
| » Starters: Harry Byrd vs Art Ditmar | Sixth | 17 out |
| Tuesday, July 5 |
| » Defeated Indians (46-32), 4-3 | Municipal Stadium (21-20) | 34-42 | Won 2 |
| » Starters: Early Wynn vs Bobby Shantz | Sixth | 16½ out |
| Wednesday, July 6 |
| » Lost to Indians (47-32), 8-4 | Municipal Stadium (21-21) | 34-43 | |
| » Starters: Herb Score vs Alex Kellner | Sixth | 16½ out |
| Thursday, July 7 |
| » Lost to Indians (48-32), 9-1 | Municipal Stadium (21-22) | 34-44 | Lost 2 |
| » Starters: Mike Garcia vs Art Ceccarelli | Sixth | 17 out |
| Friday, July 8 |
| » Lost to Tigers (40-38), 11-8 | Tiger Stadium (2-3) | 34-45 | Lost 3 |
| » Starters: Arnie Portocarrero vs Billy Hoeft | Sixth | 18 out |
| Saturday, July 9 |
| » Defeated Tigers (40-39), 2-1 | Tiger Stadium (3-3) | 35-45 | |
| » Starters: Art Ditmar vs Frank Lary | Sixth | 18 out |
| Future Athletic Willie Wilson is born in Montgomery, AL. |
| Sunday, July 10 |
| » Defeated Tigers (40-40), 9-5 | Tiger Stadium (4-3) | 36-45 | Won 2 |
| » Starters: Cloyd Boyer vs Steve Gromek | Sixth | 18 out |
| » Lost to Tigers (41-40), 10-1 | Tiger Stadium (4-4) | 36-46 | |
| » Starters: Vic Raschi vs Ned Garver | Sixth | 18 out |
| Thursday, July 14 |
| » Lost to Orioles (24-55), 10-7 | Municipal Stadium (21-23) | 36-47 | Lost 2 |
| » Starters: Jim Wilson vs Art Ceccarelli | Sixth | 18½ out |
| » Lost to Orioles (25-55), 6-4 | Municipal Stadium (21-24) | 36-48 | Lost 3 |
| » Starters: Ray Moore vs Art Ditmar | Sixth | 18½ out |
| Friday, July 15 |
| » Lost to Orioles (26-55), 8-5 | Municipal Stadium (21-25) | 36-49 | Lost 4 |
| » Starters: Jim McDonald vs Bobby Shantz | Sixth | 19½ out |
| Saturday, July 16 |
| » Lost to Senators (28-57), 8-7 | Municipal Stadium (21-26) | 36-50 | Lost 5 |
| » Starters: Dean Stone vs Alex Kellner | Sixth | 19 out |
| Sunday, July 17 |
| » Lost to Senators (29-57), 4-0 | Municipal Stadium (21-27) | 36-51 | Lost 6 |
| » Starters: Spec Shea vs Vic Raschi | Sixth | 19 out |
| Monday, July 18 |
| » Lost to Senators (30-57), 6-3 | Municipal Stadium (21-28) | 36-52 | Lost 7 |
| » Starters: Ted Abernathy vs Cloyd Boyer | Sixth | 19½ out |
| Tuesday, July 19 |
| » Lost to Red Sox (51-39), 6-3 | Municipal Stadium (21-29) | 36-53 | Lost 8 |
| » Starters: Willard Nixon vs Art Ditmar | Sixth | 20½ out |
| Wednesday, July 20 |
| » Lost to Red Sox (52-39), 6-0 | Municipal Stadium (21-30) | 36-54 | Lost 9 |
| » Starters: George Susce vs Arnie Portocarrero | Sixth | 20½ out |
| Thursday, July 21 |
| » Lost to Red Sox (53-39), 4-3 | Municipal Stadium (21-31) | 36-55 | Lost 10 |
| » Starters: Frank Sullivan vs Bobby Shantz | Sixth | 20½ out |
| Friday, July 22 |
| » Defeated Yankees (57-36), 3-1 | Municipal Stadium (22-31) | 37-55 | |
| » Starters: Tom Sturdivant vs Vic Raschi | Sixth | 19½ out |
| Saturday, July 23 |
| » Defeated Yankees (57-37), 8-7 | Municipal Stadium (23-31) | 38-55 | Won 2 |
| » Starters: Bob Turley vs Ray Herbert | Sixth | 18½ out |
| Sunday, July 24 |
| » Lost to Yankees (58-37), 7-3 | Municipal Stadium (23-32) | 38-56 | |
| » Starters: Whitey Ford vs Art Ditmar | Sixth | 20½ out |
| » Lost to Yankees (59-37), 2-0 | Municipal Stadium (23-33) | 38-57 | Lost 2 |
| » Starters: Johnny Kucks vs Arnie Portocarrero | Sixth | 20½ out |
| Tuesday, July 26 |
| » Lost to Senators (34-61), 9-3 | Griffith Stadium (3-2) | 38-58 | Lost 3 |
| » Starters: Cloyd Boyer vs Bob Porterfield | Sixth | 21 out |
| » Defeated Senators (34-62), 3-1 | Griffith Stadium (4-2) | 39-58 | |
| » Starters: Alex Kellner vs Spec Shea | Sixth | 21 out |
| Wednesday, July 27 |
| » Defeated Senators (34-63), 6-4 | Griffith Stadium (5-2) | 40-58 | Won 2 |
| » Starters: Bobby Shantz vs Dean Stone | Sixth | 19½ out |
| » Defeated Senators (34-64), 4-1 | Griffith Stadium (6-2) | 41-58 | Won 3 |
| » Starters: Ray Herbert vs Johnny Schmitz | Sixth | 19½ out |
| Friday, July 29 |
| » Lost to Yankees (61-39), 3-2 | Yankee Stadium (1-5) | 41-59 | |
| » Starters: Vic Raschi vs Whitey Ford | Sixth | 20 out |
| Saturday, July 30 |
| » Defeated Yankees (61-40), 12-2 | Yankee Stadium (2-5) | 42-59 | |
| » Starters: Arnie Portocarrero vs Johnny Kucks | Fifth | 19 out |
| Sunday, July 31 |
| » Lost to Yankees (62-40), 5-2 | Yankee Stadium (2-6) | 42-60 | |
| » Starters: Cloyd Boyer vs Don Larsen | Fifth | 20 out |
| » Defeated Yankees (62-41), 7-1 | Yankee Stadium (3-6) | 43-60 | |
| » Starters: Art Ditmar vs Bob Wiesler | Fifth | 20 out |
| Tuesday, August 2 |
| » Lost to Orioles (31-71), 5-1 | Memorial Stadium (4-2) | 43-61 | |
| » Starters: Bobby Shantz vs Bill Wight | Sixth | 21 out |
| Wednesday, August 3 |
| » Lost to Orioles (32-71), 4-3 | Memorial Stadium (4-3) | 43-62 | Lost 2 |
| » Starters: Art Ceccarelli vs George Zuverink | Fifth | 20½ out |
| » Defeated Orioles (32-72), 5-1 | Memorial Stadium (5-3) | 44-62 | |
| » Starters: Alex Kellner vs Art Schallock | Fifth | 20½ out |
| Thursday, August 4 |
| » Lost to Orioles (33-72), 8-1 | Memorial Stadium (5-4) | 44-63 | |
| » Starters: Bill Harrington vs Ed Lopat | Sixth | 20½ out |
| Friday, August 5 |
| » Defeated Red Sox (62-45), 5-2 | Fenway Park (1-6) | 45-63 | |
| » Starters: Vic Raschi vs Frank Sullivan | Fifth | 19½ out |
| Saturday, August 6 |
| » Defeated Red Sox (62-46), 6-5 | Fenway Park (2-6) | 46-63 | Won 2 |
| » Starters: Arnie Portocarrero vs George Susce | Fifth | 18½ out |
| Sunday, August 7 |
| » Lost to Red Sox (63-46), 16-12 | Fenway Park (2-7) | 46-64 | |
| » Starters: Art Ditmar vs Tom Brewer | Sixth | 19 out |
| Tuesday, August 9 |
| » Lost to White Sox (64-43), 4-1 | Municipal Stadium (23-34) | 46-65 | Lost 2 |
| » Starters: Billy Pierce vs Bobby Shantz | Sixth | 20 out |
| Wednesday, August 10 |
| » Defeated White Sox (64-44), 5-4 | Municipal Stadium (24-34) | 47-65 | |
| » Starters: Harry Byrd vs Alex Kellner | Sixth | 19½ out |
| Thursday, August 11 |
| » Lost to White Sox (65-44), 14-1 | Municipal Stadium (24-35) | 47-66 | |
| » Starters: Connie Johnson vs Vic Raschi | Sixth | 20½ out |
| Friday, August 12 |
| » Lost to Indians (68-45), 17-1 | Municipal Stadium (24-36) | 47-67 | Lost 2 |
| » Starters: Bob Lemon vs Arnie Portocarrero | Sixth | 22½ out |
| » Lost to Indians (69-45), 6-5 | Municipal Stadium (24-37) | 47-68 | Lost 3 |
| » Starters: Art Houtteman vs Art Ditmar | Sixth | 22½ out |
| Saturday, August 13 |
| » Lost to Indians (70-45), 5-3 | Municipal Stadium (24-38) | 47-69 | Lost 4 |
| » Starters: Herb Score vs Art Ceccarelli | Sixth | 23½ out |
| Sunday, August 14 |
| » Defeated Indians (70-46), 7-3 | Municipal Stadium (25-38) | 48-69 | |
| » Starters: Mike Garcia vs Bobby Shantz | Sixth | 22½ out |
| Tuesday, August 16 |
| » Lost to White Sox (68-45), 5-4 | Comiskey Park I (2-4) | 48-70 | |
| » Starters: Alex Kellner vs Connie Johnson | Sixth | 24 out |
| Thursday, August 18 |
| » Lost to White Sox (69-45), 6-2 | Comiskey Park I (2-5) | 48-71 | Lost 2 |
| » Starters: Ray Herbert vs Virgil Trucks | Sixth | 23½ out |
| » Defeated White Sox (69-46), 5-3 | Comiskey Park I (3-5) | 49-71 | |
| » Starters: Arnie Portocarrero vs Harry Byrd | Sixth | 23½ out |
| Friday, August 19 |
| » Lost to Indians (72-48), 2-1 | Cleveland Stadium (1-6) | 49-72 | |
| » Starters: Vic Raschi vs Mike Garcia | Sixth | 24½ out |
| Saturday, August 20 |
| » Lost to Indians (73-48), 7-5 | Cleveland Stadium (1-7) | 49-73 | Lost 2 |
| » Starters: Art Ceccarelli vs Early Wynn | Sixth | 25½ out |
| Sunday, August 21 |
| » Lost to Indians (74-48), 9-4 | Cleveland Stadium (1-8) | 49-74 | Lost 3 |
| » Starters: Art Ditmar vs Bob Lemon | Sixth | 26½ out |
| Tuesday, August 23 |
| » Defeated Senators (42-77), 4-3 | Municipal Stadium (26-38) | 50-74 | |
| » Starters: Dean Stone vs Alex Kellner | Sixth | 25½ out |
| Wednesday, August 24 |
| » Defeated Senators (42-78), 5-0 | Municipal Stadium (27-38) | 51-74 | Won 2 |
| » Starters: Ted Abernathy vs Arnie Portocarrero | Sixth | 25½ out |
| Thursday, August 25 |
| » Defeated Orioles (39-83), 9-2 | Municipal Stadium (28-38) | 52-74 | Won 3 |
| » Starters: Hal Brown vs Art Ceccarelli | Sixth | 25½ out |
| Friday, August 26 |
| » Defeated Orioles (39-84), 3-2 | Municipal Stadium (29-38) | 53-74 | Won 4 |
| » Starters: Ray Moore vs Mike Kume | Sixth | 24½ out |
| Sunday, August 28 |
| » Lost to Red Sox (74-54), 14-2 | Municipal Stadium (29-39) | 53-75 | |
| » Starters: Frank Sullivan vs Vic Raschi | Sixth | 24½ out |
| Tuesday, August 30 |
| » Defeated Yankees (78-52), 4-3 | Municipal Stadium (30-39) | 54-75 | |
| » Starters: Rip Coleman vs Alex Kellner | Fifth | 24 out |
| Wednesday, August 31 |
| » Lost to Yankees (79-52), 11-6 | Municipal Stadium (30-40) | 54-76 | |
| » Starters: Tommy Byrne vs Arnie Portocarrero | Fifth | 25 out |
| Friday, September 2 |
| » Defeated Tigers (67-66), 7-6 | Municipal Stadium (31-40) | 55-76 | |
| » Starters: Paul Foytack vs Art Ceccarelli | Sixth | 25 out |
| Saturday, September 3 |
| » Lost to Tigers (68-66), 11-6 | Municipal Stadium (31-41) | 55-77 | |
| » Starters: Steve Gromek vs Mike Kume | Fifth | 25 out |
| Sunday, September 4 |
| » Lost to Tigers (69-66), 17-1 | Municipal Stadium (31-42) | 55-78 | Lost 2 |
| » Starters: Ned Garver vs Vic Raschi | Sixth | 26 out |
| Monday, September 5 |
| » Defeated Indians (82-54), 5-4 | Cleveland Stadium (2-8) | 56-78 | |
| » Starters: Art Ditmar vs Bob Feller | Sixth | 26 out |
| » Lost to Indians (83-54), 9-2 | Cleveland Stadium (2-9) | 56-79 | |
| » Starters: Alex Kellner vs Herb Score | Sixth | 26 out |
| Wednesday, September 7 |
| » Lost to Yankees (83-54), 2-1 | Yankee Stadium (3-7) | 56-80 | Lost 2 |
| » Starters: Arnie Portocarrero vs Whitey Ford | Sixth | 27 out |
| Thursday, September 8 |
| » Lost to Yankees (84-54), 13-0 | Yankee Stadium (3-8) | 56-81 | Lost 3 |
| » Starters: Art Ceccarelli vs Bob Turley | Sixth | 28 out |
| Friday, September 9 |
| » Lost to Senators (49-86), 6-5 | Griffith Stadium (6-3) | 56-82 | Lost 4 |
| » Starters: Alex Kellner vs Mickey McDermott | Sixth | 28½ out |
| » Defeated Senators (49-87), 7-6 | Griffith Stadium (7-3) | 57-82 | |
| » Starters: Gus Keriazakos vs Dean Stone | Sixth | 28½ out |
| Saturday, September 10 |
| » Defeated Senators (49-88), 8-6 | Griffith Stadium (8-3) | 58-82 | Won 2 |
| » Starters: Johnny Gray vs Webbo Clarke | Sixth | 28½ out |
| Sunday, September 11 |
| » Defeated Orioles (44-93), 4-3 | Memorial Stadium (6-4) | 59-82 | Won 3 |
| » Starters: Walt Craddock vs George Zuverink | Sixth | 28½ out |
| » Lost to Orioles (45-93), 4-2 | Memorial Stadium (6-5) | 59-83 | |
| » Starters: Mike Kume vs Ed Lopat | Sixth | 28½ out |
| Tuesday, September 13 |
| » Defeated Red Sox (81-61), 6-5 | Fenway Park (3-7) | 60-83 | |
| » Starters: Vic Raschi vs Willard Nixon | Sixth | 29½ out |
| » Lost to Red Sox (82-61), 7-6 | Fenway Park (3-8) | 60-84 | |
| » Starters: Arnie Portocarrero vs Frank Baumann | Sixth | 29½ out |
| Wednesday, September 14 |
| » Defeated Red Sox (82-62), 7-3 | Fenway Park (4-8) | 61-84 | |
| » Starters: Art Ditmar vs Ike Delock | Sixth | 28½ out |
| Friday, September 16 |
| » Defeated White Sox (86-61), 13-7 | Municipal Stadium (32-42) | 62-84 | Won 2 |
| » Starters: Connie Johnson vs Alex Kellner | Sixth | 27½ out |
| Saturday, September 17 |
| » Lost to White Sox (87-61), 12-8 | Municipal Stadium (32-43) | 62-85 | |
| » Starters: Bob Keegan vs Johnny Gray | Sixth | 28½ out |
| Sunday, September 18 |
| » Defeated White Sox (87-62), 8-1 | Municipal Stadium (33-43) | 63-85 | |
| » Starters: Dick Donovan vs Art Ditmar | Sixth | 28½ out |
| Monday, September 19 |
| » Lost to Tigers (76-73), 4-0 | Tiger Stadium (4-5) | 63-86 | |
| » Starters: Walt Craddock vs Bud Black | Sixth | 29 out |
| Tuesday, September 20 |
| » Lost to Tigers (77-73), 7-3 | Tiger Stadium (4-6) | 63-87 | Lost 2 |
| » Starters: Glenn Cox vs Duke Maas | Sixth | 30½ out |
| Wednesday, September 21 |
| » Lost to Tigers (78-73), 10-1 | Tiger Stadium (4-7) | 63-88 | Lost 3 |
| » Starters: Mike Kume vs Dick Marlowe | Sixth | 31½ out |
| Friday, September 23 |
| » Lost to White Sox (89-63), 12-4 | Comiskey Park I (3-6) | 63-89 | Lost 4 |
| » Starters: Arnie Portocarrero vs Sandy Consuegra | Sixth | 32 out |
| Saturday, September 24 |
| » Lost to White Sox (90-63), 4-0 | Comiskey Park I (3-7) | 63-90 | Lost 5 |
| » Starters: Johnny Gray vs Dick Donovan | Sixth | 32½ out |
| Sunday, September 25 |
| » Lost to White Sox (91-63), 5-0 | Comiskey Park I (3-8) | 63-91 | Lost 6 |
| » Starters: Glenn Cox vs Billy Pierce | Sixth | 33 out |
| Wednesday, November 9 |
| Future Athletic Jeff Cox is born in Los Angeles, CA. |
| Wednesday, November 23 |
| Future Athletic Mark Smith is born in Arlington, VA. |
| Saturday, November 26 |
| Future Athletic Jay Howell is born in Miami, FL. |
Game information provided by Retrosheet (www.retrosheet.org) |