| Saturday, January 16 |
| Former White Sox Fred Payne dies in Camden, NY at the age of 74. |
| Sunday, January 17 |
| Future White Sox Jerry Turner is born in Texarkana, AR. |
| Saturday, January 30 |
| Future White Sox Dave Stegman is born in Inglewood, CA. |
| Saturday, March 13 |
| Future White Sox Terry Leach is born in Selma, AL. |
| Tuesday, April 13 |
| » Lost to Indians (1-0), 8-2 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Early Wynn vs Billy Pierce | Second | 1 out |
| Wednesday, April 14 |
| » Lost to Indians (2-0), 6-3 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » Starters: Bob Lemon vs Jack Harshman | Fifth | 2 out |
| Future White Sox Casey Parsons is born in Wenatchee, WA. |
| Thursday, April 15 |
| » Lost to Orioles (2-1), 3-1 | Memorial Stadium (0-1) | 0-3 | Lost 3 |
| » Starters: Virgil Trucks vs Bob Turley | Fourth | 2 out |
| Saturday, April 17 |
| » Defeated Indians (2-2), 8-1 | Cleveland Stadium (1-0) | 1-3 | |
| » Starters: Bob Keegan vs Art Houtteman | Sixth | 2 out |
| » Major-league debuts: Ray Narleski (Indians) |
| Sunday, April 18 |
| » Defeated Indians (2-3), 6-2 | Cleveland Stadium (2-0) | 2-3 | Won 2 |
| » Starters: Billy Pierce vs Early Wynn | Third | 2 out |
| Monday, April 19 |
| » Defeated Tigers (4-2), 5-1 | Tiger Stadium (1-0) | 3-3 | Won 3 |
| » Starters: Jack Harshman vs Billy Hoeft | Third | 1 out |
| Tuesday, April 20 |
| » Defeated Tigers (4-3), 7-2 | Tiger Stadium (2-0) | 4-3 | Won 4 |
| » Starters: Virgil Trucks vs Ted Gray | First | -- |
| Friday, April 23 |
| » Lost to Orioles (4-4), 3-1 | Comiskey Park I (0-3) | 4-4 | |
| » Starters: Joe Coleman vs Billy Pierce | Third | 1 out |
| Saturday, April 24 |
| » Defeated Orioles (4-5), 14-4 | Comiskey Park I (1-3) | 5-4 | |
| » Starters: Vern Bickford vs Bob Keegan | Second | 1 out |
| » Major-league debuts: Chico Garcia (Orioles) |
| Sunday, April 25 |
| » Defeated Orioles (4-6), 3-2 | Comiskey Park I (2-3) | 6-4 | Won 2 |
| » Starters: Don Larsen vs Virgil Trucks | First | -- |
| » Defeated Orioles (4-7), 4-3 | Comiskey Park I (3-3) | 7-4 | Won 3 |
| » Starters: Lou Kretlow vs Mike Fornieles | First | -- |
| Tuesday, April 27 |
| » Defeated Yankees (5-6), 4-3 | Yankee Stadium (1-0) | 8-4 | Won 4 |
| » Starters: Don Johnson vs Whitey Ford | First | -- |
| Thursday, April 29 |
| » Lost to Yankees (6-6), 5-4 | Yankee Stadium (1-1) | 8-5 | |
| » Starters: Billy Pierce vs Ed Lopat | First | -- |
| Friday, April 30 |
| » Defeated Red Sox (4-8), 5-0 | Fenway Park (1-0) | 9-5 | |
| » Starters: Bob Keegan vs Sid Hudson | First | -- |
| Saturday, May 1 |
| » Defeated Red Sox (4-9), 3-0 | Fenway Park (2-0) | 10-5 | Won 2 |
| » Starters: Virgil Trucks vs Bill Henry | First | -- |
| Sunday, May 2 |
| » Defeated Athletics (7-6), 4-0 | Shibe Park (1-0) | 11-5 | Won 3 |
| » Starters: Don Johnson vs Morrie Martin | First | -- |
| » Lost to Athletics (8-6), 2-1 | Shibe Park (1-1) | 11-6 | |
| » Starters: Mike Fornieles vs Arnie Portocarrero | First | -- |
| Monday, May 3 |
| » Defeated Athletics (8-7), 14-3 | Shibe Park (2-1) | 12-6 | |
| » Starters: Sandy Consuegra vs Carl Scheib | First | -- |
| Tuesday, May 4 |
| » Defeated Senators (6-10), 8-6 | Griffith Stadium (1-0) | 13-6 | Won 2 |
| » Starters: Billy Pierce vs Mickey McDermott | First | -- |
| Wednesday, May 5 |
| » Lost to Senators (7-10), 1-0 | Griffith Stadium (1-1) | 13-7 | |
| » Starters: Bob Keegan vs Bob Porterfield | First | -- |
| Thursday, May 6 |
| » Defeated Senators (7-11), 5-4 | Griffith Stadium (2-1) | 14-7 | |
| » Starters: Virgil Trucks vs Camilo Pascual | First | -- |
| Saturday, May 8 |
| » Lost to Tigers (10-5), 12-1 | Comiskey Park I (3-4) | 14-8 | |
| » Starters: Ned Garver vs Don Johnson | Second | 3½ out |
| Sunday, May 9 |
| » Lost to Tigers (11-5), 3-2 | Comiskey Park I (3-5) | 14-9 | Lost 2 |
| » Starters: Steve Gromek vs Sandy Consuegra | Second | 3½ out |
| » Tied Tigers, 0-0 | Comiskey Park I (3-5) | 14-9 | |
| » Starters: Billy Hoeft vs Billy Pierce | Second | 3½ out |
| Tuesday, May 11 |
| » Defeated Red Sox (5-10), 2-1 | Comiskey Park I (4-5) | 15-9 | |
| » Starters: Leo Kiely vs Bob Keegan | Second | 3½ out |
| Wednesday, May 12 |
| » Defeated Red Sox (5-11), 1-0 | Comiskey Park I (5-5) | 16-9 | Won 2 |
| » Starters: Tom Brewer vs Don Johnson | Second | 3½ out |
| Thursday, May 13 |
| » Lost to Athletics (10-13), 3-2 | Comiskey Park I (5-6) | 16-10 | |
| » Starters: Morrie Martin vs Virgil Trucks | Second | 3½ out |
| Friday, May 14 |
| » Defeated Athletics (10-14), 4-3 | Comiskey Park I (6-6) | 17-10 | |
| » Starters: Alex Kellner vs Billy Pierce | First | -- |
| Saturday, May 15 |
| » Defeated Athletics (10-15), 7-6 | Comiskey Park I (7-6) | 18-10 | Won 2 |
| » Starters: Bob Trice vs Sandy Consuegra | First | -- |
| Sunday, May 16 |
| » Defeated Senators (8-17), 10-5 | Comiskey Park I (8-6) | 19-10 | Won 3 |
| » Starters: Connie Marrero vs Bob Keegan | Second | 1 out |
| » Lost to Senators (9-17), 3-1 | Comiskey Park I (8-7) | 19-11 | |
| » Starters: Bob Porterfield vs Mike Fornieles | Second | 1 out |
| Tuesday, May 18 |
| » Lost to Yankees (18-11), 4-3 | Comiskey Park I (8-8) | 19-12 | Lost 2 |
| » Starters: Tom Morgan vs Virgil Trucks | Third | 1 out |
| Wednesday, May 19 |
| » Lost to Yankees (19-11), 3-2 | Comiskey Park I (8-9) | 19-13 | Lost 3 |
| » Starters: Ed Lopat vs Billy Pierce | Fourth | 2 out |
| Friday, May 21 |
| » Defeated Tigers (16-11), 8-0 | Tiger Stadium (3-0) | 20-13 | |
| » Starters: Bob Keegan vs Billy Hoeft | Third | 2 out |
| Saturday, May 22 |
| » Defeated Tigers (16-12), 5-3 | Tiger Stadium (4-0) | 21-13 | Won 2 |
| » Starters: Don Johnson vs Ned Garver | Third | 2 out |
| Sunday, May 23 |
| » Defeated Tigers (16-13), 4-3 | Tiger Stadium (5-0) | 22-13 | Won 3 |
| » Starters: Virgil Trucks vs Steve Gromek | Second | 2½ out |
| Tuesday, May 25 |
| » Defeated Indians (24-11), 4-2 | Comiskey Park I (9-9) | 23-13 | Won 4 |
| » Starters: Bob Lemon vs Billy Pierce | Second | 1½ out |
| Wednesday, May 26 |
| » Defeated Indians (24-12), 5-4 | Comiskey Park I (10-9) | 24-13 | Won 5 |
| » Starters: Mike Garcia vs Bob Keegan | Second | ½ out |
| Friday, May 28 |
| » Defeated Orioles (12-23), 11-6 | Memorial Stadium (1-1) | 25-13 | Won 6 |
| » Starters: Mike Fornieles vs Lou Kretlow | Second | 1 out |
| » Defeated Orioles (12-24), 14-8 | Memorial Stadium (2-1) | 26-13 | Won 7 |
| » Starters: Don Johnson vs Bob Turley | Second | 1 out |
| Saturday, May 29 |
| » Defeated Orioles (12-25), 11-4 | Memorial Stadium (3-1) | 27-13 | Won 8 |
| » Starters: Virgil Trucks vs Joe Coleman | Second | 1 out |
| Sunday, May 30 |
| » Lost to Orioles (13-25), 5-2 | Memorial Stadium (3-2) | 27-14 | |
| » Starters: Al Sima vs Don Larsen | Second | 1 out |
| Monday, May 31 |
| » Defeated Indians (27-13), 6-4 | Cleveland Stadium (3-0) | 28-14 | |
| » Starters: Bob Keegan vs Bob Feller | Second | 1 out |
| » Lost to Indians (28-13), 6-3 | Cleveland Stadium (3-1) | 28-15 | |
| » Starters: Don Johnson vs Art Houtteman | Second | 1 out |
| Wednesday, June 2 |
| » Lost to Red Sox (14-22), 5-2 | Fenway Park (2-1) | 28-16 | Lost 2 |
| » Starters: Sandy Consuegra vs Frank Sullivan | Second | 2 out |
| Thursday, June 3 |
| » Defeated Red Sox (14-23), 9-6 | Fenway Park (3-1) | 29-16 | |
| » Starters: Virgil Trucks vs Hal Brown | Second | 1 out |
| Friday, June 4 |
| » Defeated Red Sox (14-24), 7-3 | Fenway Park (4-1) | 30-16 | Won 2 |
| » Starters: Bob Keegan vs Willard Nixon | Second | 1 out |
| Saturday, June 5 |
| » Defeated Senators (19-26), 5-3 | Griffith Stadium (3-1) | 31-16 | Won 3 |
| » Starters: Don Johnson vs Johnny Schmitz | Second | 1 out |
| Sunday, June 6 |
| » Defeated Senators (19-27), 5-3 | Griffith Stadium (4-1) | 32-16 | Won 4 |
| » Starters: Sandy Consuegra vs Chuck Stobbs | Second | 1 out |
| » Defeated Senators (19-28), 6-0 | Griffith Stadium (5-1) | 33-16 | Won 5 |
| » Starters: Jack Harshman vs Camilo Pascual | Second | 1 out |
| Tuesday, June 8 |
| » Defeated Athletics (17-32), 9-3 | Shibe Park (3-1) | 34-16 | Won 6 |
| » Starters: Virgil Trucks vs Bob Trice | First | -- |
| Wednesday, June 9 |
| » Defeated Athletics (17-33), 9-4 | Shibe Park (4-1) | 35-16 | Won 7 |
| » Starters: Bob Keegan vs Alex Kellner | First | -- |
| Friday, June 11 |
| » Lost to Yankees (33-21), 3-2 | Yankee Stadium (1-2) | 35-17 | |
| » Starters: Don Johnson vs Allie Reynolds | First | -- |
| Saturday, June 12 |
| » Lost to Yankees (34-21), 2-0 | Yankee Stadium (1-3) | 35-18 | Lost 2 |
| » Starters: Jack Harshman vs Whitey Ford | Second | ½ out |
| Sunday, June 13 |
| » Lost to Yankees (35-21), 4-2 | Yankee Stadium (1-4) | 35-19 | Lost 3 |
| » Starters: Sandy Consuegra vs Ed Lopat | Second | 1½ out |
| » Defeated Yankees (35-22), 8-0 | Yankee Stadium (2-4) | 36-19 | |
| » Starters: Virgil Trucks vs Harry Byrd | Second | 1½ out |
| Tuesday, June 15 |
| » Lost to Athletics (22-34), 11-4 | Comiskey Park I (10-10) | 36-20 | |
| » Starters: Marion Fricano vs Bob Keegan | Second | 3 out |
| » Major-league debuts: Ron Jackson (White Sox) |
| Wednesday, June 16 |
| » Defeated Athletics (22-35), 11-6 | Comiskey Park I (11-10) | 37-20 | |
| » Starters: Bob Trice vs Mike Fornieles | Second | 3 out |
| Thursday, June 17 |
| » Defeated Athletics (22-36), 6-4 | Comiskey Park I (12-10) | 38-20 | Won 2 |
| » Starters: Alex Kellner vs Jack Harshman | Second | 3 out |
| Friday, June 18 |
| » Lost to Yankees (39-22), 7-6 | Comiskey Park I (12-11) | 38-21 | |
| » Starters: Harry Byrd vs Virgil Trucks | Second | 4 out |
| Saturday, June 19 |
| » Defeated Yankees (39-23), 3-0 | Comiskey Park I (13-11) | 39-21 | |
| » Starters: Ed Lopat vs Sandy Consuegra | Second | 3 out |
| Sunday, June 20 |
| » Lost to Yankees (40-23), 16-6 | Comiskey Park I (13-12) | 39-22 | |
| » Starters: Allie Reynolds vs Billy Pierce | Second | 4 out |
| » Defeated Yankees (40-24), 7-3 | Comiskey Park I (14-12) | 40-22 | |
| » Starters: Whitey Ford vs Bob Keegan | Second | 4 out |
| » Major-league debuts: Vito Valentinetti (White Sox) |
| Tuesday, June 22 |
| » Defeated Senators (27-35), 7-5 | Comiskey Park I (15-12) | 41-22 | Won 2 |
| » Starters: Mickey McDermott vs Virgil Trucks | Second | 3 out |
| Wednesday, June 23 |
| » Defeated Senators (27-36), 8-6 | Comiskey Park I (16-12) | 42-22 | Won 3 |
| » Starters: Bob Porterfield vs Jack Harshman | Second | 3 out |
| » Major-league debuts: Harmon Killebrew (Senators) |
| Thursday, June 24 |
| » Defeated Senators (27-37), 5-2 | Comiskey Park I (17-12) | 43-22 | Won 4 |
| » Starters: Johnny Schmitz vs Sandy Consuegra | Second | 2 out |
| Friday, June 25 |
| » Defeated Red Sox (22-40), 6-4 | Comiskey Park I (18-12) | 44-22 | Won 5 |
| » Starters: Willard Nixon vs Bob Keegan | Second | 1 out |
| Saturday, June 26 |
| » Lost to Red Sox (23-40), 3-1 | Comiskey Park I (18-13) | 44-23 | |
| » Starters: Frank Sullivan vs Don Johnson | Second | 1 out |
| Sunday, June 27 |
| » Lost to Red Sox (24-40), 2-1 | Comiskey Park I (18-14) | 44-24 | Lost 2 |
| » Starters: Tom Brewer vs Virgil Trucks | Second | 1½ out |
| » Defeated Red Sox (24-41), 9-1 | Comiskey Park I (19-14) | 45-24 | |
| » Starters: Bill Henry vs Jack Harshman | Second | 1½ out |
| Tuesday, June 29 |
| » Lost to Tigers (30-36), 10-3 | Comiskey Park I (19-15) | 45-25 | |
| » Starters: Ned Garver vs Billy Pierce | Second | 2 out |
| » Defeated Tigers (30-37), 5-0 | Comiskey Park I (20-15) | 46-25 | |
| » Starters: Steve Gromek vs Sandy Consuegra | Second | 2 out |
| Wednesday, June 30 |
| » Lost to Tigers (31-37), 4-3 | Comiskey Park I (20-16) | 46-26 | |
| » Starters: George Zuverink vs Bob Keegan | Second | 3 out |
| Friday, July 2 |
| » Lost to Indians (49-22), 3-2 | Cleveland Stadium (3-2) | 46-27 | Lost 2 |
| » Starters: Virgil Trucks vs Bob Feller | Third | 5 out |
| » Lost to Indians (50-22), 5-4 | Cleveland Stadium (3-3) | 46-28 | Lost 3 |
| » Starters: Don Johnson vs Early Wynn | Third | 5 out |
| Saturday, July 3 |
| » Lost to Indians (51-22), 5-4 | Cleveland Stadium (3-4) | 46-29 | Lost 4 |
| » Starters: Sandy Consuegra vs Art Houtteman | Third | 6 out |
| Sunday, July 4 |
| » Lost to Indians (52-22), 2-1 | Cleveland Stadium (3-5) | 46-30 | Lost 5 |
| » Starters: Bob Keegan vs Mike Garcia | Third | 7 out |
| Monday, July 5 |
| » Defeated Orioles (30-45), 3-0 | Comiskey Park I (21-16) | 47-30 | |
| » Starters: Don Larsen vs Billy Pierce | Third | 6 out |
| » Defeated Orioles (30-46), 2-1 | Comiskey Park I (22-16) | 48-30 | Won 2 |
| » Starters: Duane Pillette vs Harry Dorish | Third | 6 out |
| Tuesday, July 6 |
| » Defeated Tigers (32-42), 4-0 | Tiger Stadium (6-0) | 49-30 | Won 3 |
| » Starters: Virgil Trucks vs Al Aber | Third | 6 out |
| Wednesday, July 7 |
| » Defeated Tigers (32-43), 9-0 | Tiger Stadium (7-0) | 50-30 | Won 4 |
| » Starters: Don Johnson vs Billy Hoeft | Third | 6 out |
| Thursday, July 8 |
| » Lost to Tigers (33-43), 2-0 | Tiger Stadium (7-1) | 50-31 | |
| » Starters: Sandy Consuegra vs Steve Gromek | Third | 7 out |
| Friday, July 9 |
| » Defeated Indians (56-24), 8-3 | Comiskey Park I (23-16) | 51-31 | |
| » Starters: Art Houtteman vs Bob Keegan | Third | 6 out |
| Saturday, July 10 |
| » Defeated Indians (56-25), 3-0 | Comiskey Park I (24-16) | 52-31 | Won 2 |
| » Starters: Early Wynn vs Jack Harshman | Third | 5 out |
| Sunday, July 11 |
| » Defeated Indians (56-26), 3-0 | Comiskey Park I (25-16) | 53-31 | Won 3 |
| » Starters: Ray Narleski vs Billy Pierce | Third | 3 out |
| » Defeated Indians (56-27), 8-2 | Comiskey Park I (26-16) | 54-31 | Won 4 |
| » Starters: Bob Lemon vs Virgil Trucks | Third | 3 out |
| Thursday, July 15 |
| » Lost to Senators (33-47), 3-2 | Griffith Stadium (5-2) | 54-32 | |
| » Starters: Bob Keegan vs Johnny Schmitz | Third | 4 out |
| Friday, July 16 |
| » Defeated Senators (33-48), 4-2 | Griffith Stadium (6-2) | 55-32 | |
| » Starters: Virgil Trucks vs Dean Stone | Third | 4 out |
| Saturday, July 17 |
| » Lost to Senators (34-48), 3-1 | Griffith Stadium (6-3) | 55-33 | |
| » Starters: Billy Pierce vs Bob Porterfield | Third | 5 out |
| Sunday, July 18 |
| » Defeated Athletics (30-53), 10-2 | Shibe Park (5-1) | 56-33 | |
| » Starters: Jack Harshman vs Johnny Gray | Third | 4 out |
| » Defeated Athletics (30-54), 4-3 | Shibe Park (6-1) | 57-33 | Won 2 |
| » Starters: Don Johnson vs Charlie Bishop | Third | 4 out |
| Tuesday, July 20 |
| » Lost to Yankees (62-29), 4-1 | Yankee Stadium (2-5) | 57-34 | |
| » Starters: Bob Keegan vs Whitey Ford | Third | 5 out |
| Wednesday, July 21 |
| » Defeated Yankees (62-30), 15-3 | Yankee Stadium (3-5) | 58-34 | |
| » Starters: Virgil Trucks vs Bob Wiesler | Third | 4½ out |
| Thursday, July 22 |
| » Lost to Yankees (63-30), 4-3 | Yankee Stadium (3-6) | 58-35 | |
| » Starters: Sandy Consuegra vs Bob Grim | Third | 6½ out |
| » Lost to Yankees (64-30), 11-1 | Yankee Stadium (3-7) | 58-36 | Lost 2 |
| » Starters: Billy Pierce vs Harry Byrd | Third | 6½ out |
| Friday, July 23 |
| » Defeated Red Sox (37-53), 7-1 | Fenway Park (5-1) | 59-36 | |
| » Starters: Harry Dorish vs Russ Kemmerer | Third | 6½ out |
| Saturday, July 24 |
| » Lost to Red Sox (38-53), 5-2 | Fenway Park (5-2) | 59-37 | |
| » Starters: Bob Keegan vs Leo Kiely | Third | 7½ out |
| Sunday, July 25 |
| » Defeated Red Sox (38-54), 5-2 | Fenway Park (6-2) | 60-37 | |
| » Starters: Jack Harshman vs Willard Nixon | Third | 6 out |
| » Defeated Red Sox (38-55), 4-2 | Fenway Park (7-2) | 61-37 | Won 2 |
| » Starters: Don Johnson vs Tom Brewer | Third | 6 out |
| Tuesday, July 27 |
| » Defeated Yankees (65-33), 4-0 | Comiskey Park I (27-16) | 62-37 | Won 3 |
| » Starters: Harry Byrd vs Virgil Trucks | Third | 6 out |
| Wednesday, July 28 |
| » Lost to Yankees (66-33), 7-5 | Comiskey Park I (27-17) | 62-38 | |
| » Starters: Ed Lopat vs Billy Pierce | Third | 7 out |
| Thursday, July 29 |
| » Lost to Yankees (67-33), 10-0 | Comiskey Park I (27-18) | 62-39 | Lost 2 |
| » Starters: Whitey Ford vs Jack Harshman | Third | 7 out |
| Former White Sox Babe Borton dies in Berkeley, CA at the age of 66. |
| Friday, July 30 |
| » Defeated Athletics (35-63), 4-2 | Comiskey Park I (28-18) | 63-39 | |
| » Starters: Arnie Portocarrero vs Bob Keegan | Third | 7 out |
| Saturday, July 31 |
| » Defeated Athletics (35-64), 7-1 | Comiskey Park I (29-18) | 64-39 | Won 2 |
| » Starters: Charlie Bishop vs Morrie Martin | Third | 7 out |
| Sunday, August 1 |
| » Defeated Athletics (35-65), 6-5 | Comiskey Park I (30-18) | 65-39 | Won 3 |
| » Starters: Marion Fricano vs Sandy Consuegra | Third | 7 out |
| » Defeated Athletics (35-66), 12-1 | Comiskey Park I (31-18) | 66-39 | Won 4 |
| » Starters: Sonny Dixon vs Virgil Trucks | Third | 7 out |
| Tuesday, August 3 |
| » Defeated Red Sox (41-59), 6-2 | Comiskey Park I (32-18) | 67-39 | Won 5 |
| » Starters: Frank Sullivan vs Jack Harshman | Third | 6 out |
| Wednesday, August 4 |
| » Defeated Red Sox (41-60), 6-5 | Comiskey Park I (33-18) | 68-39 | Won 6 |
| » Starters: Russ Kemmerer vs Billy Pierce | Third | 6 out |
| Thursday, August 5 |
| » Defeated Red Sox (41-61), 5-1 | Comiskey Park I (34-18) | 69-39 | Won 7 |
| » Starters: Tom Brewer vs Bob Keegan | Third | 5 out |
| Friday, August 6 |
| » Defeated Senators (44-59), 10-5 | Comiskey Park I (35-18) | 70-39 | Won 8 |
| » Starters: Johnny Schmitz vs Virgil Trucks | Third | 5 out |
| Saturday, August 7 |
| » Lost to Senators (45-59), 4-3 | Comiskey Park I (35-19) | 70-40 | |
| » Starters: Mickey McDermott vs Sandy Consuegra | Third | 6 out |
| Future White Sox Steve Kemp is born in San Angelo, TX. |
| Sunday, August 8 |
| » Lost to Senators (46-59), 7-6 | Comiskey Park I (35-20) | 70-41 | Lost 2 |
| » Starters: Chuck Stobbs vs Billy Pierce | Third | 7 out |
| » Defeated Senators (46-60), 3-0 | Comiskey Park I (36-20) | 71-41 | |
| » Starters: Dean Stone vs Jack Harshman | Third | 7 out |
| Tuesday, August 10 |
| » Lost to Orioles (39-72), 3-1 | Comiskey Park I (36-21) | 71-42 | |
| » Starters: Lou Kretlow vs Bob Keegan | Third | 7 out |
| Wednesday, August 11 |
| » Defeated Orioles (39-73), 1-0 | Comiskey Park I (37-21) | 72-42 | |
| » Starters: Bob Kuzava vs Virgil Trucks | Third | 7 out |
| Friday, August 13 |
| » Defeated Tigers (50-62), 1-0 | Comiskey Park I (38-21) | 73-42 | Won 2 |
| » Starters: Al Aber vs Jack Harshman | Third | 7½ out |
| Saturday, August 14 |
| » Defeated Tigers (50-63), 4-3 | Comiskey Park I (39-21) | 74-42 | Won 3 |
| » Starters: Billy Hoeft vs Sandy Consuegra | Third | 7½ out |
| Former White Sox Fabian Kowalik dies in Karnes City, TX at the age of 47. |
| Sunday, August 15 |
| » Lost to Tigers (51-63), 2-1 | Comiskey Park I (39-22) | 74-43 | |
| » Starters: Steve Gromek vs Harry Dorish | Third | 9½ out |
| » Lost to Tigers (52-63), 8-7 | Comiskey Park I (39-23) | 74-44 | Lost 2 |
| » Starters: Ned Garver vs Virgil Trucks | Third | 9½ out |
| Tuesday, August 17 |
| » Defeated Orioles (39-78), 2-0 | Memorial Stadium (4-2) | 75-44 | |
| » Starters: Billy Pierce vs Bob Turley | Third | 9 out |
| » Defeated Orioles (39-79), 3-1 | Memorial Stadium (5-2) | 76-44 | Won 2 |
| » Starters: Don Johnson vs Bob Kuzava | Third | 9 out |
| Wednesday, August 18 |
| » Defeated Orioles (39-80), 4-1 | Memorial Stadium (6-2) | 77-44 | Won 3 |
| » Starters: Sandy Consuegra vs Don Larsen | Third | 9 out |
| Thursday, August 19 |
| » Defeated Orioles (39-81), 4-3 | Memorial Stadium (7-2) | 78-44 | Won 4 |
| » Starters: Jack Harshman vs Lou Kretlow | Third | 8½ out |
| Friday, August 20 |
| » Defeated Tigers (53-67), 8-2 | Tiger Stadium (8-1) | 79-44 | Won 5 |
| » Starters: Virgil Trucks vs Steve Gromek | Third | 8½ out |
| Saturday, August 21 |
| » Defeated Tigers (53-68), 2-1 | Tiger Stadium (9-1) | 80-44 | Won 6 |
| » Starters: Bob Keegan vs George Zuverink | Third | 8½ out |
| Sunday, August 22 |
| » Lost to Tigers (54-68), 7-4 | Tiger Stadium (9-2) | 80-45 | |
| » Starters: Billy Pierce vs Billy Hoeft | Third | 9½ out |
| Tuesday, August 24 |
| » Defeated Senators (51-70), 4-0 | Griffith Stadium (7-3) | 81-45 | |
| » Starters: Jack Harshman vs Dean Stone | Third | 8½ out |
| Wednesday, August 25 |
| » Defeated Senators (51-71), 7-2 | Griffith Stadium (8-3) | 82-45 | Won 2 |
| » Starters: Billy Pierce vs Bunky Stewart | Third | 8½ out |
| Thursday, August 26 |
| » Defeated Athletics (41-83), 8-1 | Shibe Park (7-1) | 83-45 | Won 3 |
| » Starters: Sandy Consuegra vs Arnie Portocarrero | Third | 9 out |
| » Lost to Athletics (42-83), 4-1 | Shibe Park (7-2) | 83-46 | |
| » Starters: Don Johnson vs Charlie Bishop | Third | 9 out |
| » Major-league debuts: Joe Taylor (Athletics) |
| Friday, August 27 |
| » Defeated Athletics (42-84), 11-0 | Shibe Park (8-2) | 84-46 | |
| » Starters: Harry Dorish vs Marion Fricano | Third | 8 out |
| Saturday, August 28 |
| » Defeated Athletics (42-85), 5-2 | Shibe Park (9-2) | 85-46 | Won 2 |
| » Starters: Jack Harshman vs Alex Kellner | Third | 8 out |
| Sunday, August 29 |
| » Lost to Yankees (89-40), 4-1 | Yankee Stadium (3-8) | 85-47 | |
| » Starters: Virgil Trucks vs Whitey Ford | Third | 9½ out |
| Tuesday, August 31 |
| Future White Sox Jack Perconte is born in Joliet, IL. Future White Sox Claudell Washington is born in Los Angeles, CA. |
| Wednesday, September 1 |
| » Lost to Red Sox (57-72), 7-2 | Fenway Park (7-3) | 85-48 | Lost 2 |
| » Starters: Billy Pierce vs Russ Kemmerer | Third | 10 out |
| » Defeated Red Sox (57-73), 6-3 | Fenway Park (8-3) | 86-48 | |
| » Starters: Harry Dorish vs Mel Parnell | Third | 10 out |
| Friday, September 3 |
| » Lost to Indians (96-38), 3-2 | Comiskey Park I (39-24) | 86-49 | |
| » Starters: Bob Feller vs Virgil Trucks | Third | 10½ out |
| Saturday, September 4 |
| » Defeated Indians (96-39), 8-5 | Comiskey Park I (40-24) | 87-49 | |
| » Starters: Early Wynn vs Jack Harshman | Third | 9½ out |
| Sunday, September 5 |
| » Lost to Indians (97-39), 8-2 | Comiskey Park I (40-25) | 87-50 | |
| » Starters: Art Houtteman vs Billy Pierce | Third | 10½ out |
| Former White Sox Maurice Archdeacon dies in St.Louis, MO at the age of 57. |
| Monday, September 6 |
| » Lost to Tigers (60-76), 9-1 | Comiskey Park I (40-26) | 87-51 | Lost 2 |
| » Starters: Ned Garver vs Bob Keegan | Third | 11½ out |
| » Lost to Tigers (61-76), 3-2 | Comiskey Park I (40-27) | 87-52 | Lost 3 |
| » Starters: George Zuverink vs Virgil Trucks | Third | 11½ out |
| Wednesday, September 8 |
| » Defeated Senators (59-79), 2-1 | Comiskey Park I (41-27) | 88-52 | |
| » Starters: Bob Porterfield vs Morrie Martin | Third | 11½ out |
| Thursday, September 9 |
| » Lost to Senators (60-79), 2-0 | Comiskey Park I (41-28) | 88-53 | |
| » Starters: Chuck Stobbs vs Harry Dorish | Third | 12½ out |
| Friday, September 10 |
| » Lost to Yankees (95-45), 6-3 | Comiskey Park I (41-29) | 88-54 | Lost 2 |
| » Starters: Bob Grim vs Virgil Trucks | Third | 13½ out |
| Saturday, September 11 |
| » Defeated Yankees (95-46), 6-5 | Comiskey Park I (42-29) | 89-54 | |
| » Starters: Ed Lopat vs Jack Harshman | Third | 13½ out |
| Sunday, September 12 |
| » Defeated Red Sox (63-78), 5-3 | Comiskey Park I (43-29) | 90-54 | Won 2 |
| » Starters: Tom Brewer vs Bob Keegan | Third | 13½ out |
| » Defeated Red Sox (63-79), 7-5 | Comiskey Park I (44-29) | 91-54 | Won 3 |
| » Starters: Frank Sullivan vs Billy Pierce | Third | 13½ out |
| Tuesday, September 14 |
| » Lost to Athletics (49-96), 1-0 | Comiskey Park I (44-30) | 91-55 | |
| » Manager: Marty Marion |
| » Starters: Arnie Portocarrero vs Virgil Trucks | Third | 14½ out |
| Friday, September 17 |
| » Lost to Orioles (51-96), 5-1 | Comiskey Park I (44-31) | 91-56 | Lost 2 |
| » Starters: Bob Turley vs Jack Harshman | Third | 15½ out |
| Saturday, September 18 |
| » Defeated Orioles (51-97), 6-2 | Comiskey Park I (45-31) | 92-56 | |
| » Starters: Don Larsen vs Billy Pierce | Third | 15½ out |
| Sunday, September 19 |
| » Lost to Orioles (52-97), 5-1 | Comiskey Park I (45-32) | 92-57 | |
| » Starters: Duane Pillette vs Virgil Trucks | Third | 16½ out |
| Monday, September 20 |
| » Lost to Indians (109-40), 7-4 | Cleveland Stadium (3-6) | 92-58 | Lost 2 |
| » Starters: Bob Keegan vs Bob Feller | Third | 17½ out |
| Tuesday, September 21 |
| » Defeated Indians (109-41), 9-7 | Cleveland Stadium (4-6) | 93-58 | |
| » Starters: Mike Fornieles vs Art Houtteman | Third | 16½ out |
| Wednesday, September 22 |
| » Lost to Indians (110-41), 3-1 | Cleveland Stadium (4-7) | 93-59 | |
| » Starters: Jack Harshman vs Don Mossi | Third | 17½ out |
| Friday, September 24 |
| » Lost to Orioles (54-99), 2-1 | Memorial Stadium (7-3) | 93-60 | Lost 2 |
| » Starters: Virgil Trucks vs Billy O'Dell | Third | 17½ out |
| Saturday, September 25 |
| » Defeated Orioles (54-100), 11-0 | Memorial Stadium (8-3) | 94-60 | |
| » Starters: Billy Pierce vs Don Larsen | Third | 17½ out |
| » Major-league debuts: Ryne Duren (Orioles) |
| Sunday, October 3 |
| Future White Sox Bert Roberge is born in Lewiston, ME. |
| Friday, October 22 |
| Future White Sox Jamie Quirk is born in Whittier, CA. |
| Monday, November 1 |
| Future White Sox Miguel Dilone is born in Santiago, D.R. |
| Thursday, December 2 |
| Future White Sox Julio Cruz is born in Brooklyn, NY. |
| Saturday, December 11 |
| Former White Sox Henry Courtney dies in Lyme, CT at the age of 57. |
Game information provided by Retrosheet (www.retrosheet.org) |
