| Saturday, January 16 |
| Former Tiger Fred Payne dies in Camden, NY at the age of 74. |
| Sunday, January 17 |
| Future Tiger Jerry Turner is born in Texarkana, AR. |
| Saturday, January 30 |
| Future Tiger Dave Stegman is born in Inglewood, CA. |
| Thursday, March 4 |
| Future Tiger Mark Wagner is born in Conneaut, OH. |
| Friday, March 12 |
| Future Tiger Larry Rothschild is born in Chicago, IL. |
| Tuesday, April 13 |
| » Defeated Orioles (0-1), 3-0 | Tiger Stadium (1-0) | 1-0 | |
| » Starters: Don Larsen vs Steve Gromek | First | -- |
| » Major-league debuts: Frank Bolling (Tigers) |
| Wednesday, April 14 |
| » Lost to Orioles (1-1), 3-2 | Tiger Stadium (1-1) | 1-1 | |
| » Starters: Duane Pillette vs Ray Herbert | Third | 1 out |
| Thursday, April 15 |
| » Defeated Indians (2-1), 3-2 | Cleveland Stadium (1-0) | 2-1 | |
| » Starters: Ted Gray vs Mike Garcia | First | -- |
| Saturday, April 17 |
| » Defeated Orioles (2-2), 1-0 | Memorial Stadium (1-0) | 3-1 | Won 2 |
| » Starters: Ned Garver vs Joe Coleman | First | -- |
| Sunday, April 18 |
| » Defeated Orioles (2-3), 8-3 | Memorial Stadium (2-0) | 4-1 | Won 3 |
| » Starters: Steve Gromek vs Don Larsen | First | -- |
| Monday, April 19 |
| » Lost to White Sox (3-3), 5-1 | Tiger Stadium (1-2) | 4-2 | |
| » Starters: Jack Harshman vs Billy Hoeft | First | -- |
| Tuesday, April 20 |
| » Lost to White Sox (4-3), 7-2 | Tiger Stadium (1-3) | 4-3 | Lost 2 |
| » Starters: Virgil Trucks vs Ted Gray | First | -- |
| Friday, April 23 |
| » Defeated Indians (3-5), 6-1 | Tiger Stadium (2-3) | 5-3 | |
| » Starters: Early Wynn vs Ned Garver | First | -- |
| Saturday, April 24 |
| » Defeated Indians (3-6), 6-3 | Tiger Stadium (3-3) | 6-3 | Won 2 |
| » Starters: Hal Newhouser vs Steve Gromek | First | -- |
| Sunday, April 25 |
| » Lost to Indians (4-6), 10-9 | Tiger Stadium (3-4) | 6-4 | |
| » Starters: Bob Lemon vs Billy Hoeft | Second | ½ out |
| Friday, April 30 |
| » Defeated Senators (6-6), 2-1 | Griffith Stadium (1-0) | 7-4 | |
| » Starters: Ned Garver vs Bob Porterfield | Second | 1½ out |
| Saturday, May 1 |
| » Defeated Senators (6-7), 6-1 | Griffith Stadium (2-0) | 8-4 | Won 2 |
| » Starters: Steve Gromek vs Spec Shea | Second | 1½ out |
| Sunday, May 2 |
| » Lost to Yankees (7-8), 12-4 | Yankee Stadium (0-1) | 8-5 | |
| » Starters: Ted Gray vs Jim McDonald | Second | 1½ out |
| » Defeated Yankees (7-9), 4-0 | Yankee Stadium (1-1) | 9-5 | |
| » Starters: Billy Hoeft vs Harry Byrd | Second | 1½ out |
| Future Tiger Keith Moreland is born in Dallas, TX. |
| Saturday, May 8 |
| » Defeated White Sox (14-8), 12-1 | Comiskey Park I (1-0) | 10-5 | Won 2 |
| » Starters: Ned Garver vs Don Johnson | First | -- |
| Sunday, May 9 |
| » Defeated White Sox (14-9), 3-2 | Comiskey Park I (2-0) | 11-5 | Won 3 |
| » Starters: Steve Gromek vs Sandy Consuegra | First | -- |
| » Tied White Sox, 0-0 | Comiskey Park I (2-0) | 11-5 | |
| » Starters: Billy Hoeft vs Billy Pierce | First | -- |
| Tuesday, May 11 |
| » Lost to Senators (8-12), 5-3 | Tiger Stadium (3-5) | 11-6 | |
| » Starters: Bob Porterfield vs Ralph Branca | First | -- |
| Wednesday, May 12 |
| » Defeated Senators (8-13), 4-2 | Tiger Stadium (4-5) | 12-6 | |
| » Starters: Camilo Pascual vs Ted Gray | First | -- |
| Thursday, May 13 |
| » Lost to Yankees (14-10), 5-3 | Tiger Stadium (4-6) | 12-7 | |
| » Starters: Tom Morgan vs Ned Garver | First | -- |
| Friday, May 14 |
| » Lost to Yankees (15-10), 6-4 | Tiger Stadium (4-7) | 12-8 | Lost 2 |
| » Starters: Harry Byrd vs Steve Gromek | Third | 3½ out |
| Saturday, May 15 |
| » Lost to Yankees (16-10), 7-5 | Tiger Stadium (4-8) | 12-9 | Lost 3 |
| » Starters: Jim McDonald vs Billy Hoeft | Third | 3½ out |
| Sunday, May 16 |
| » Defeated Red Sox (6-14), 7-6 | Tiger Stadium (5-8) | 13-9 | |
| » Starters: Hal Brown vs Ted Gray | Third | 2½ out |
| » Defeated Red Sox (6-15), 9-8 | Tiger Stadium (6-8) | 14-9 | Won 2 |
| » Starters: Leo Kiely vs Ralph Branca | Third | 2½ out |
| Monday, May 17 |
| » Lost to Red Sox (7-15), 4-3 | Tiger Stadium (6-9) | 14-10 | |
| » Starters: Tom Brewer vs Ned Garver | Fourth | 2 out |
| Tuesday, May 18 |
| » Defeated Athletics (10-18), 8-3 | Tiger Stadium (7-9) | 15-10 | |
| » Starters: Morrie Martin vs Steve Gromek | Fourth | 2 out |
| Wednesday, May 19 |
| » Defeated Athletics (10-19), 4-3 | Tiger Stadium (8-9) | 16-10 | Won 2 |
| » Starters: Alex Kellner vs Ralph Branca | Third | 2 out |
| Friday, May 21 |
| » Lost to White Sox (20-13), 8-0 | Tiger Stadium (8-10) | 16-11 | |
| » Starters: Bob Keegan vs Billy Hoeft | Fourth | 3 out |
| Saturday, May 22 |
| » Lost to White Sox (21-13), 5-3 | Tiger Stadium (8-11) | 16-12 | Lost 2 |
| » Starters: Don Johnson vs Ned Garver | Fourth | 4 out |
| Sunday, May 23 |
| » Lost to White Sox (22-13), 4-3 | Tiger Stadium (8-12) | 16-13 | Lost 3 |
| » Starters: Virgil Trucks vs Steve Gromek | Fourth | 5½ out |
| Tuesday, May 25 |
| » Defeated Orioles (12-20), 5-4 | Tiger Stadium (9-12) | 17-13 | |
| » Starters: Joe Coleman vs Billy Hoeft | Fourth | 4½ out |
| Wednesday, May 26 |
| » Defeated Orioles (12-21), 6-3 | Tiger Stadium (10-12) | 18-13 | Won 2 |
| » Starters: Don Larsen vs George Zuverink | Fourth | 3½ out |
| Thursday, May 27 |
| » Defeated Orioles (12-22), 7-1 | Tiger Stadium (11-12) | 19-13 | Won 3 |
| » Starters: Duane Pillette vs Ned Garver | Fourth | 3 out |
| Friday, May 28 |
| » Lost to Indians (25-12), 3-0 | Cleveland Stadium (1-1) | 19-14 | |
| » Starters: Steve Gromek vs Early Wynn | Fourth | 4 out |
| Saturday, May 29 |
| » Lost to Indians (26-12), 12-0 | Cleveland Stadium (1-2) | 19-15 | Lost 2 |
| » Starters: Ray Herbert vs Bob Lemon | Fourth | 5 out |
| Sunday, May 30 |
| » Lost to Indians (27-12), 3-1 | Cleveland Stadium (1-3) | 19-16 | Lost 3 |
| » Starters: Dick Marlowe vs Mike Garcia | Fourth | 6 out |
| Monday, May 31 |
| » Defeated Orioles (13-26), 7-5 | Memorial Stadium (3-0) | 20-16 | |
| » Starters: George Zuverink vs Bob Turley | Fourth | 6 out |
| » Lost to Orioles (14-26), 4-2 | Memorial Stadium (3-1) | 20-17 | |
| » Starters: Billy Hoeft vs Duane Pillette | Fourth | 6 out |
| Tuesday, June 1 |
| » Defeated Orioles (14-27), 4-3 | Memorial Stadium (4-1) | 21-17 | |
| » Starters: Ralph Branca vs Lou Kretlow | Fourth | 5½ out |
| Wednesday, June 2 |
| » Lost to Senators (18-24), 7-2 | Griffith Stadium (2-1) | 21-18 | |
| » Starters: Steve Gromek vs Dean Stone | Fourth | 6½ out |
| Thursday, June 3 |
| » Lost to Senators (19-24), 4-3 | Griffith Stadium (2-2) | 21-19 | Lost 2 |
| » Starters: Ned Garver vs Mickey McDermott | Fourth | 6½ out |
| Friday, June 4 |
| » Defeated Senators (19-25), 3-2 | Griffith Stadium (3-2) | 22-19 | |
| » Starters: Billy Hoeft vs Bob Porterfield | Fourth | 5½ out |
| Saturday, June 5 |
| » Defeated Red Sox (14-25), 6-0 | Fenway Park (1-0) | 23-19 | Won 2 |
| » Starters: George Zuverink vs Bill Henry | Fourth | 6 out |
| » Lost to Red Sox (15-25), 5-4 | Fenway Park (1-1) | 23-20 | |
| » Starters: Dick Marlowe vs Leo Kiely | Fourth | 6 out |
| Sunday, June 6 |
| » Lost to Red Sox (16-25), 7-4 | Fenway Park (1-2) | 23-21 | Lost 2 |
| » Starters: Ralph Branca vs Willard Nixon | Fourth | 7½ out |
| Monday, June 7 |
| » Lost to Red Sox (17-25), 3-2 | Fenway Park (1-3) | 23-22 | Lost 3 |
| » Starters: Steve Gromek vs Frank Sullivan | Fourth | 8½ out |
| » Lost to Red Sox (18-25), 5-4 | Fenway Park (1-4) | 23-23 | Lost 4 |
| » Starters: Ned Garver vs Tom Brewer | Fourth | 8½ out |
| Tuesday, June 8 |
| » Defeated Yankees (30-21), 8-0 | Yankee Stadium (2-1) | 24-23 | |
| » Starters: Billy Hoeft vs Ed Lopat | Fourth | 8½ out |
| Wednesday, June 9 |
| » Lost to Yankees (31-21), 5-1 | Yankee Stadium (2-2) | 24-24 | |
| » Starters: George Zuverink vs Whitey Ford | Fourth | 9½ out |
| Thursday, June 10 |
| » Lost to Yankees (32-21), 9-5 | Yankee Stadium (2-3) | 24-25 | Lost 2 |
| » Starters: Al Aber vs Jim McDonald | Fourth | 10 out |
| Friday, June 11 |
| » Defeated Athletics (17-34), 16-5 | Shibe Park (1-0) | 25-25 | |
| » Starters: Dick Weik vs Arnie Portocarrero | Fourth | 9½ out |
| » Lost to Athletics (18-34), 2-1 | Shibe Park (1-1) | 25-26 | |
| » Starters: Steve Gromek vs Marion Fricano | Fourth | 9½ out |
| Saturday, June 12 |
| » Lost to Athletics (19-34), 4-2 | Shibe Park (1-2) | 25-27 | Lost 2 |
| » Starters: Ned Garver vs Bob Trice | Fourth | 10 out |
| Sunday, June 13 |
| » Lost to Athletics (20-34), 4-3 | Shibe Park (1-3) | 25-28 | Lost 3 |
| » Starters: Billy Hoeft vs Alex Kellner | Fourth | 12 out |
| » Lost to Athletics (21-34), 6-3 | Shibe Park (1-4) | 25-29 | Lost 4 |
| » Starters: George Zuverink vs Arnie Portocarrero | Fourth | 12 out |
| Tuesday, June 15 |
| » Defeated Red Sox (19-34), 4-1 | Tiger Stadium (12-12) | 26-29 | |
| » Starters: Leo Kiely vs Steve Gromek | Fourth | 12½ out |
| Wednesday, June 16 |
| » Lost to Red Sox (20-34), 3-2 | Tiger Stadium (12-13) | 26-30 | |
| » Starters: Willard Nixon vs Ned Garver | Fourth | 13½ out |
| Thursday, June 17 |
| » Defeated Red Sox (20-35), 2-1 | Tiger Stadium (13-13) | 27-30 | |
| » Starters: Tom Brewer vs George Zuverink | Fourth | 13½ out |
| Friday, June 18 |
| » Lost to Athletics (23-36), 2-1 | Tiger Stadium (13-14) | 27-31 | |
| » Starters: Arnie Portocarrero vs Billy Hoeft | Fourth | 14½ out |
| Saturday, June 19 |
| » Lost to Athletics (24-36), 5-4 | Tiger Stadium (13-15) | 27-32 | Lost 2 |
| » Starters: Marion Fricano vs Al Aber | Fourth | 14½ out |
| Tuesday, June 22 |
| » Defeated Yankees (40-25), 4-1 | Tiger Stadium (14-15) | 28-32 | |
| » Starters: Bob Wiesler vs Steve Gromek | Fourth | 14½ out |
| Wednesday, June 23 |
| » Lost to Yankees (41-25), 9-4 | Tiger Stadium (14-16) | 28-33 | |
| » Starters: Jim McDonald vs Billy Hoeft | Fourth | 15½ out |
| Thursday, June 24 |
| » Lost to Yankees (42-25), 11-2 | Tiger Stadium (14-17) | 28-34 | Lost 2 |
| » Starters: Tom Morgan vs Ned Garver | Fourth | 15½ out |
| Friday, June 25 |
| » Lost to Senators (28-37), 4-3 | Tiger Stadium (14-18) | 28-35 | Lost 3 |
| » Starters: Dean Stone vs George Zuverink | Fourth | 15½ out |
| Saturday, June 26 |
| » Defeated Senators (28-38), 5-4 | Tiger Stadium (15-18) | 29-35 | |
| » Starters: Connie Marrero vs Al Aber | Fourth | 14½ out |
| Sunday, June 27 |
| » Lost to Senators (29-38), 8-2 | Tiger Stadium (15-19) | 29-36 | |
| » Starters: Bob Porterfield vs Billy Hoeft | Fourth | 15½ out |
| Tuesday, June 29 |
| » Defeated White Sox (45-25), 10-3 | Comiskey Park I (3-0) | 30-36 | |
| » Starters: Ned Garver vs Billy Pierce | Fourth | 16 out |
| » Lost to White Sox (46-25), 5-0 | Comiskey Park I (3-1) | 30-37 | |
| » Starters: Steve Gromek vs Sandy Consuegra | Fourth | 16 out |
| Wednesday, June 30 |
| » Defeated White Sox (46-26), 4-3 | Comiskey Park I (4-1) | 31-37 | |
| » Starters: George Zuverink vs Bob Keegan | Fourth | 16 out |
| Friday, July 2 |
| » Lost to Orioles (28-44), 2-0 | Memorial Stadium (4-2) | 31-38 | |
| » Starters: Al Aber vs Joe Coleman | Fourth | 17½ out |
| Saturday, July 3 |
| » Lost to Orioles (29-44), 5-3 | Memorial Stadium (4-3) | 31-39 | Lost 2 |
| » Starters: Billy Hoeft vs Bob Turley | Fourth | 18½ out |
| Sunday, July 4 |
| » Lost to Orioles (30-44), 3-1 | Memorial Stadium (4-4) | 31-40 | Lost 3 |
| » Starters: Steve Gromek vs Lou Kretlow | Fourth | 19½ out |
| Monday, July 5 |
| » Lost to Indians (53-22), 13-6 | Tiger Stadium (15-20) | 31-41 | Lost 4 |
| » Starters: Dave Hoskins vs Ned Garver | Fourth | 19½ out |
| » Defeated Indians (53-23), 1-0 | Tiger Stadium (16-20) | 32-41 | |
| » Starters: Don Mossi vs George Zuverink | Fourth | 19½ out |
| Tuesday, July 6 |
| » Lost to White Sox (49-30), 4-0 | Tiger Stadium (16-21) | 32-42 | |
| » Starters: Virgil Trucks vs Al Aber | Fourth | 20½ out |
| Future Tiger Jason Thompson is born in Hollywood, CA. |
| Wednesday, July 7 |
| » Lost to White Sox (50-30), 9-0 | Tiger Stadium (16-22) | 32-43 | Lost 2 |
| » Starters: Don Johnson vs Billy Hoeft | Fourth | 21½ out |
| Thursday, July 8 |
| » Defeated White Sox (50-31), 2-0 | Tiger Stadium (17-22) | 33-43 | |
| » Starters: Sandy Consuegra vs Steve Gromek | Fourth | 21½ out |
| Friday, July 9 |
| » Lost to Orioles (31-49), 7-5 | Tiger Stadium (17-23) | 33-44 | |
| » Starters: Duane Pillette vs George Zuverink | Fourth | 21½ out |
| Saturday, July 10 |
| » Defeated Orioles (31-50), 2-1 | Tiger Stadium (18-23) | 34-44 | |
| » Starters: Joe Coleman vs Ned Garver | Fourth | 20½ out |
| Sunday, July 11 |
| » Defeated Orioles (31-51), 2-1 | Tiger Stadium (19-23) | 35-44 | Won 2 |
| » Starters: Bob Turley vs Al Aber | Fourth | 19 out |
| Thursday, July 15 |
| » Lost to Red Sox (32-48), 3-1 | Fenway Park (1-5) | 35-45 | |
| » Starters: Steve Gromek vs Willard Nixon | Fourth | 19½ out |
| » Defeated Red Sox (32-49), 4-2 | Fenway Park (2-5) | 36-45 | |
| » Starters: George Zuverink vs Leo Kiely | Fourth | 19½ out |
| Friday, July 16 |
| » Lost to Red Sox (33-49), 3-0 | Fenway Park (2-6) | 36-46 | |
| » Starters: Ned Garver vs Frank Sullivan | Fourth | 20½ out |
| Saturday, July 17 |
| » Lost to Red Sox (34-49), 7-6 | Fenway Park (2-7) | 36-47 | Lost 2 |
| » Starters: Ray Herbert vs Tom Brewer | Fourth | 21½ out |
| Sunday, July 18 |
| » Lost to Yankees (60-28), 6-0 | Yankee Stadium (2-4) | 36-48 | Lost 3 |
| » Starters: Billy Hoeft vs Harry Byrd | Fourth | 21½ out |
| » Defeated Yankees (60-29), 8-6 | Yankee Stadium (3-4) | 37-48 | |
| » Starters: Al Aber vs Bob Grim | Fourth | 21½ out |
| Future Tiger Harry Spilman is born in Albany, GA. |
| Monday, July 19 |
| » Lost to Yankees (61-29), 8-0 | Yankee Stadium (3-5) | 37-49 | |
| » Starters: Ted Gray vs Allie Reynolds | Fourth | 22½ out |
| Tuesday, July 20 |
| » Defeated Athletics (30-55), 12-0 | Shibe Park (2-4) | 38-49 | |
| » Starters: Steve Gromek vs Alex Kellner | Fourth | 21½ out |
| » Defeated Athletics (30-56), 4-3 | Shibe Park (3-4) | 39-49 | Won 2 |
| » Starters: Ned Garver vs Arnie Portocarrero | Fourth | 21½ out |
| Wednesday, July 21 |
| » Lost to Athletics (31-56), 4-1 | Shibe Park (3-5) | 39-50 | |
| » Starters: George Zuverink vs Sonny Dixon | Fourth | 22 out |
| Thursday, July 22 |
| » Defeated Athletics (31-57), 9-4 | Shibe Park (4-5) | 40-50 | |
| » Starters: Ray Herbert vs Charlie Bishop | Fourth | 22½ out |
| Friday, July 23 |
| » Lost to Senators (39-50), 8-3 | Griffith Stadium (3-3) | 40-51 | |
| » Starters: Al Aber vs Chuck Stobbs | Fourth | 23½ out |
| Saturday, July 24 |
| » Lost to Senators (40-50), 2-1 | Griffith Stadium (3-4) | 40-52 | Lost 2 |
| » Starters: Billy Hoeft vs Dean Stone | Fifth | 24½ out |
| Sunday, July 25 |
| » Lost to Senators (41-50), 11-3 | Griffith Stadium (3-5) | 40-53 | Lost 3 |
| » Starters: Ted Gray vs Spec Shea | Fifth | 24½ out |
| Tuesday, July 27 |
| » Defeated Athletics (34-59), 3-2 | Tiger Stadium (20-23) | 41-53 | |
| » Starters: Charlie Bishop vs Steve Gromek | Fifth | 25 out |
| » Lost to Athletics (35-59), 8-3 | Tiger Stadium (20-24) | 41-54 | |
| » Starters: Marion Fricano vs Ned Garver | Fifth | 25 out |
| Wednesday, July 28 |
| » Defeated Athletics (35-60), 10-2 | Tiger Stadium (21-24) | 42-54 | |
| » Starters: Alex Kellner vs Al Aber | Fifth | 25 out |
| Thursday, July 29 |
| » Defeated Athletics (35-61), 4-2 | Tiger Stadium (22-24) | 43-54 | Won 2 |
| » Starters: Johnny Gray vs George Zuverink | Fourth | 23½ out |
| » Defeated Athletics (35-62), 7-3 | Tiger Stadium (23-24) | 44-54 | Won 3 |
| » Starters: Sonny Dixon vs Billy Hoeft | Fourth | 23½ out |
| Friday, July 30 |
| » Defeated Red Sox (39-58), 5-0 | Tiger Stadium (24-24) | 45-54 | Won 4 |
| » Starters: Willard Nixon vs Ned Garver | Fourth | 23½ out |
| » Major-league debuts: Tom Hurd (Red Sox) |
| Saturday, July 31 |
| » Lost to Red Sox (40-58), 4-0 | Tiger Stadium (24-25) | 45-55 | |
| » Starters: Tom Brewer vs Steve Gromek | Fourth | 24½ out |
| Sunday, August 1 |
| » Lost to Red Sox (41-58), 10-8 | Tiger Stadium (24-26) | 45-56 | Lost 2 |
| » Starters: Mel Parnell vs Al Aber | Fourth | 26 out |
| Monday, August 2 |
| » Lost to Senators (43-56), 11-6 | Tiger Stadium (24-27) | 45-57 | Lost 3 |
| » Starters: Dean Stone vs George Zuverink | Fourth | 26½ out |
| Tuesday, August 3 |
| » Defeated Senators (43-57), 2-0 | Tiger Stadium (25-27) | 46-57 | |
| » Starters: Chuck Stobbs vs Billy Hoeft | Fourth | 25½ out |
| Wednesday, August 4 |
| » Defeated Senators (43-58), 6-2 | Tiger Stadium (26-27) | 47-57 | Won 2 |
| » Starters: Connie Marrero vs Ned Garver | Fourth | 25½ out |
| Thursday, August 5 |
| » Lost to Senators (44-58), 4-1 | Tiger Stadium (26-28) | 47-58 | |
| » Starters: Bob Porterfield vs Steve Gromek | Fourth | 25½ out |
| Friday, August 6 |
| » Lost to Yankees (73-35), 4-3 | Tiger Stadium (26-29) | 47-59 | Lost 2 |
| » Starters: Harry Byrd vs Al Aber | Fourth | 26½ out |
| Saturday, August 7 |
| » Defeated Yankees (73-36), 3-1 | Tiger Stadium (27-29) | 48-59 | |
| » Starters: Tom Morgan vs George Zuverink | Fourth | 26½ out |
| Future Tiger Steve Kemp is born in San Angelo, TX. |
| Sunday, August 8 |
| » Defeated Yankees (73-37), 10-8 | Tiger Stadium (28-29) | 49-59 | Won 2 |
| » Starters: Whitey Ford vs Billy Hoeft | Fourth | 27 out |
| Tuesday, August 10 |
| » Defeated Indians (76-33), 4-0 | Tiger Stadium (29-29) | 50-59 | Won 3 |
| » Starters: Early Wynn vs Ned Garver | Fourth | 26 out |
| Wednesday, August 11 |
| » Lost to Indians (77-33), 2-0 | Tiger Stadium (29-30) | 50-60 | |
| » Starters: Mike Garcia vs Steve Gromek | Fourth | 27 out |
| Thursday, August 12 |
| » Lost to Indians (78-33), 10-1 | Tiger Stadium (29-31) | 50-61 | Lost 2 |
| » Starters: Bob Lemon vs George Zuverink | Fourth | 28 out |
| Friday, August 13 |
| » Lost to White Sox (73-42), 1-0 | Comiskey Park I (4-2) | 50-62 | Lost 3 |
| » Starters: Al Aber vs Jack Harshman | Fourth | 29 out |
| Saturday, August 14 |
| » Lost to White Sox (74-42), 4-3 | Comiskey Park I (4-3) | 50-63 | Lost 4 |
| » Starters: Billy Hoeft vs Sandy Consuegra | Fourth | 30 out |
| Future Tiger Mark Fidrych is born in Worcester, MA. |
| Sunday, August 15 |
| » Defeated White Sox (74-43), 2-1 | Comiskey Park I (5-3) | 51-63 | |
| » Starters: Steve Gromek vs Harry Dorish | Fourth | 30 out |
| » Defeated White Sox (74-44), 8-7 | Comiskey Park I (6-3) | 52-63 | Won 2 |
| » Starters: Ned Garver vs Virgil Trucks | Fourth | 30 out |
| Tuesday, August 17 |
| » Lost to Indians (83-33), 4-3 | Cleveland Stadium (1-4) | 52-64 | |
| » Starters: George Zuverink vs Bob Lemon | Fourth | 31 out |
| Wednesday, August 18 |
| » Lost to Indians (84-33), 4-0 | Cleveland Stadium (1-5) | 52-65 | Lost 2 |
| » Starters: Billy Hoeft vs Early Wynn | Fourth | 32 out |
| Thursday, August 19 |
| » Lost to Indians (85-33), 4-3 | Cleveland Stadium (1-6) | 52-66 | Lost 3 |
| » Starters: Ned Garver vs Bob Feller | Fourth | 32 out |
| » Defeated Indians (85-34), 8-2 | Cleveland Stadium (2-6) | 53-66 | |
| » Starters: Al Aber vs Mike Garcia | Fourth | 32 out |
| Friday, August 20 |
| » Lost to White Sox (79-44), 8-2 | Tiger Stadium (29-32) | 53-67 | |
| » Starters: Virgil Trucks vs Steve Gromek | Fourth | 33 out |
| Saturday, August 21 |
| » Lost to White Sox (80-44), 2-1 | Tiger Stadium (29-33) | 53-68 | Lost 2 |
| » Starters: Bob Keegan vs George Zuverink | Fourth | 34 out |
| Sunday, August 22 |
| » Defeated White Sox (80-45), 7-4 | Tiger Stadium (30-33) | 54-68 | |
| » Starters: Billy Pierce vs Billy Hoeft | Fourth | 34 out |
| Tuesday, August 24 |
| » Defeated Red Sox (53-68), 8-7 | Fenway Park (3-7) | 55-68 | Won 2 |
| » Starters: Ned Garver vs Mel Parnell | Fourth | 33 out |
| Wednesday, August 25 |
| » Lost to Red Sox (54-68), 5-3 | Fenway Park (3-8) | 55-69 | |
| » Starters: Steve Gromek vs Willard Nixon | Fourth | 34 out |
| Thursday, August 26 |
| » Lost to Yankees (86-40), 11-2 | Yankee Stadium (3-6) | 55-70 | Lost 2 |
| » Starters: Billy Hoeft vs Bob Grim | Fourth | 35 out |
| Friday, August 27 |
| » Lost to Yankees (87-40), 4-0 | Yankee Stadium (3-7) | 55-71 | Lost 3 |
| » Starters: George Zuverink vs Tom Morgan | Fifth | 35 out |
| Saturday, August 28 |
| » Lost to Yankees (88-40), 4-2 | Yankee Stadium (3-8) | 55-72 | Lost 4 |
| » Starters: Al Aber vs Harry Byrd | Fifth | 36 out |
| Sunday, August 29 |
| » Defeated Athletics (42-86), 14-3 | Shibe Park (5-5) | 56-72 | |
| » Starters: Steve Gromek vs Johnny Gray | Fourth | 36 out |
| » Defeated Athletics (42-87), 2-1 | Shibe Park (6-5) | 57-72 | Won 2 |
| » Starters: Ned Garver vs Arnie Portocarrero | Fourth | 36 out |
| Tuesday, August 31 |
| » Lost to Senators (53-76), 5-3 | Griffith Stadium (3-6) | 57-73 | |
| » Starters: George Zuverink vs Mickey McDermott | Fifth | 37½ out |
| Wednesday, September 1 |
| » Lost to Senators (54-76), 4-0 | Griffith Stadium (3-7) | 57-74 | Lost 2 |
| » Starters: Al Aber vs Johnny Schmitz | Fifth | 37½ out |
| Thursday, September 2 |
| » Lost to Senators (55-76), 16-6 | Griffith Stadium (3-8) | 57-75 | Lost 3 |
| » Starters: Ned Garver vs Bob Porterfield | Fifth | 37½ out |
| Friday, September 3 |
| » Defeated Orioles (43-91), 4-3 | Tiger Stadium (31-33) | 58-75 | |
| » Starters: Bob Turley vs Steve Gromek | Fifth | 37½ out |
| Saturday, September 4 |
| » Defeated Orioles (43-92), 7-4 | Tiger Stadium (32-33) | 59-75 | Won 2 |
| » Starters: Joe Coleman vs Al Aber | Fourth | 36½ out |
| Sunday, September 5 |
| » Lost to Orioles (44-92), 4-3 | Tiger Stadium (32-34) | 59-76 | |
| » Starters: Lou Kretlow vs Bob Miller | Fifth | 37½ out |
| Monday, September 6 |
| » Defeated White Sox (87-51), 9-1 | Comiskey Park I (7-3) | 60-76 | |
| » Starters: Ned Garver vs Bob Keegan | Fifth | 36½ out |
| » Defeated White Sox (87-52), 3-2 | Comiskey Park I (8-3) | 61-76 | Won 2 |
| » Starters: George Zuverink vs Virgil Trucks | Fifth | 36½ out |
| Wednesday, September 8 |
| » Lost to Red Sox (62-75), 5-2 | Tiger Stadium (32-35) | 61-77 | |
| » Starters: Frank Sullivan vs Steve Gromek | Fifth | 37½ out |
| Thursday, September 9 |
| » Lost to Red Sox (63-75), 8-0 | Tiger Stadium (32-36) | 61-78 | Lost 2 |
| » Starters: Willard Nixon vs Al Aber | Fifth | 38½ out |
| Friday, September 10 |
| » Lost to Athletics (47-94), 6-5 | Tiger Stadium (32-37) | 61-79 | Lost 3 |
| » Starters: Charlie Bishop vs George Zuverink | Fifth | 39½ out |
| Saturday, September 11 |
| » Defeated Athletics (47-95), 2-1 | Tiger Stadium (33-37) | 62-79 | |
| » Starters: Marion Fricano vs Ned Garver | Fifth | 39½ out |
| Sunday, September 12 |
| » Defeated Senators (61-81), 5-0 | Tiger Stadium (34-37) | 63-79 | Won 2 |
| » Starters: Johnny Schmitz vs Steve Gromek | Fourth | 39½ out |
| » Defeated Senators (61-82), 8-3 | Tiger Stadium (35-37) | 64-79 | Won 3 |
| » Starters: Bob Porterfield vs Ted Gray | Fourth | 39½ out |
| Tuesday, September 14 |
| » Lost to Yankees (96-48), 11-0 | Tiger Stadium (35-38) | 64-80 | |
| » Starters: Tom Morgan vs Al Aber | Fourth | 40½ out |
| Thursday, September 16 |
| » Lost to Yankees (97-48), 4-2 | Tiger Stadium (35-39) | 64-81 | Lost 2 |
| » Starters: Bob Grim vs George Zuverink | Fourth | 41 out |
| Friday, September 17 |
| » Lost to Indians (106-40), 6-3 | Tiger Stadium (35-40) | 64-82 | Lost 3 |
| » Starters: Bob Lemon vs Ned Garver | Fourth | 42 out |
| » Major-league debuts: George Bullard (Tigers) |
| Future Tiger Wayne Krenchicki is born in Trenton, NJ. |
| Saturday, September 18 |
| » Lost to Indians (107-40), 3-2 | Tiger Stadium (35-41) | 64-83 | Lost 4 |
| » Starters: Early Wynn vs Steve Gromek | Fourth | 43 out |
| Sunday, September 19 |
| » Lost to Indians (108-40), 4-2 | Tiger Stadium (35-42) | 64-84 | Lost 5 |
| » Starters: Mike Garcia vs Ted Gray | Fifth | 44 out |
| Monday, September 20 |
| » Defeated Orioles (52-98), 4-3 | Memorial Stadium (5-4) | 65-84 | |
| » Starters: George Zuverink vs Joe Coleman | Fifth | 44 out |
| Tuesday, September 21 |
| » Lost to Orioles (53-98), 4-3 | Memorial Stadium (5-5) | 65-85 | |
| » Starters: Ned Garver vs Bob Turley | Fifth | 44 out |
| Wednesday, September 22 |
| » Defeated Orioles (53-99), 4-1 | Memorial Stadium (6-5) | 66-85 | |
| » Starters: Steve Gromek vs Lou Kretlow | Fifth | 44 out |
| Friday, September 24 |
| » Defeated Indians (110-42), 6-4 | Cleveland Stadium (3-6) | 67-85 | Won 2 |
| » Starters: Ted Gray vs Bob Lemon | Fourth | 43 out |
| Saturday, September 25 |
| » Lost to Indians (111-42), 11-1 | Cleveland Stadium (3-7) | 67-86 | |
| » Starters: George Zuverink vs Early Wynn | Fifth | 44 out |
| Sunday, September 26 |
| » Defeated Indians (111-43), 8-7 | Cleveland Stadium (4-7) | 68-86 | |
| » Starters: Ned Garver vs Mike Garcia | Fifth | 43 out |
| Friday, October 22 |
| Former Tiger Earl Whitehill dies in Omaha, NE at the age of 55. |
| Friday, October 29 |
| Future Tiger Kip Young is born in Georgetown, OH. |
| Sunday, November 14 |
| Future Tiger Willie Hernandez is born in Aguada, P.R. |
| Tuesday, November 30 |
| Future Tiger Juan Berenguer is born in Aguadulce, Panama. |
| Wednesday, December 1 |
| Future Tiger Dan Schatzeder is born in Elmhurst, IL. |
| Saturday, December 11 |
| Future Tiger Bob Sykes is born in Neptune, NJ. |
Game information provided by Retrosheet (www.retrosheet.org) |