| Monday, January 18 |
| Future Oriole Scott McGregor is born in Inglewood, CA. |
| Saturday, March 20 |
| Future Oriole Paul Mirabella is born in Belleville, NJ. |
| Tuesday, April 13 |
| » Lost to Tigers (1-0), 3-0 | Tiger Stadium (0-1) | 0-1 | |
| » Starters: Don Larsen vs Steve Gromek | Second | 1 out |
| » Major-league debuts: Frank Bolling (Tigers) |
| Wednesday, April 14 |
| » Defeated Tigers (1-1), 3-2 | Tiger Stadium (1-1) | 1-1 | |
| » Starters: Duane Pillette vs Ray Herbert | Third | 1 out |
| Thursday, April 15 |
| » Defeated White Sox (0-3), 3-1 | Memorial Stadium (1-0) | 2-1 | Won 2 |
| » Starters: Virgil Trucks vs Bob Turley | First | -- |
| Saturday, April 17 |
| » Lost to Tigers (3-1), 1-0 | Memorial Stadium (1-1) | 2-2 | |
| » Starters: Ned Garver vs Joe Coleman | Fourth | 1 out |
| Sunday, April 18 |
| » Lost to Tigers (4-1), 8-3 | Memorial Stadium (1-2) | 2-3 | Lost 2 |
| » Starters: Steve Gromek vs Don Larsen | Third | 2 out |
| Wednesday, April 21 |
| » Lost to Indians (3-3), 2-1 | Memorial Stadium (1-3) | 2-4 | Lost 3 |
| » Starters: Bob Lemon vs Bob Turley | Fourth | 1½ out |
| Thursday, April 22 |
| » Defeated Indians (3-4), 4-1 | Memorial Stadium (2-3) | 3-4 | |
| » Starters: Mike Garcia vs Duane Pillette | Second | 1 out |
| Friday, April 23 |
| » Defeated White Sox (4-4), 3-1 | Comiskey Park I (1-0) | 4-4 | Won 2 |
| » Starters: Joe Coleman vs Billy Pierce | Third | 1 out |
| Saturday, April 24 |
| » Lost to White Sox (5-4), 14-4 | Comiskey Park I (1-1) | 4-5 | |
| » Starters: Vern Bickford vs Bob Keegan | Fourth | 2 out |
| » Major-league debuts: Chico Garcia (Orioles) |
| Sunday, April 25 |
| » Lost to White Sox (6-4), 3-2 | Comiskey Park I (1-2) | 4-6 | Lost 2 |
| » Starters: Don Larsen vs Virgil Trucks | Fifth | 3 out |
| » Lost to White Sox (7-4), 4-3 | Comiskey Park I (1-3) | 4-7 | Lost 3 |
| » Starters: Lou Kretlow vs Mike Fornieles | Fifth | 3 out |
| Thursday, April 29 |
| » Defeated Senators (6-5), 2-1 | Griffith Stadium (1-0) | 5-7 | |
| » Starters: Bob Turley vs Mickey McDermott | Seventh | 2½ out |
| Friday, April 30 |
| » Lost to Athletics (6-5), 5-1 | Shibe Park (0-1) | 5-8 | |
| » Starters: Duane Pillette vs Bob Trice | Sixth | 3½ out |
| Saturday, May 1 |
| » Lost to Athletics (7-5), 2-1 | Shibe Park (0-2) | 5-9 | Lost 2 |
| » Starters: Lou Kretlow vs Alex Kellner | Seventh | 4½ out |
| Sunday, May 2 |
| Future Oriole Keith Moreland is born in Dallas, TX. |
| Wednesday, May 5 |
| » Lost to Yankees (8-9), 4-2 | Yankee Stadium (0-1) | 5-10 | Lost 3 |
| » Starters: Bob Turley vs Ed Lopat | Seventh | 5½ out |
| Thursday, May 6 |
| » Lost to Yankees (9-9), 9-0 | Yankee Stadium (0-2) | 5-11 | Lost 4 |
| » Starters: Joe Coleman vs Allie Reynolds | Sixth | 6½ out |
| Saturday, May 8 |
| » Lost to Indians (12-7), 5-3 | Memorial Stadium (2-4) | 5-12 | Lost 5 |
| » Starters: Mike Garcia vs Duane Pillette | Eighth | 6 out |
| Sunday, May 9 |
| » Defeated Indians (12-8), 2-1 | Memorial Stadium (3-4) | 6-12 | |
| » Starters: Art Houtteman vs Bob Turley | Eighth | 6 out |
| Monday, May 10 |
| » Defeated Athletics (9-12), 7-6 | Memorial Stadium (4-4) | 7-12 | Won 2 |
| » Starters: Marion Fricano vs Don Larsen | Sixth | 5½ out |
| Tuesday, May 11 |
| » Defeated Athletics (9-13), 2-0 | Memorial Stadium (5-4) | 8-12 | Won 3 |
| » Starters: Arnie Portocarrero vs Joe Coleman | Sixth | 4½ out |
| Thursday, May 13 |
| » Lost to Red Sox (6-11), 9-1 | Memorial Stadium (5-5) | 8-13 | |
| » Starters: Bill Henry vs Duane Pillette | Fifth | 5 out |
| Friday, May 14 |
| » Defeated Red Sox (6-12), 7-2 | Memorial Stadium (6-5) | 9-13 | |
| » Starters: Willard Nixon vs Bob Turley | Fifth | 5½ out |
| Saturday, May 15 |
| » Defeated Red Sox (6-13), 2-1 | Memorial Stadium (7-5) | 10-13 | Won 2 |
| » Starters: Tex Clevenger vs Joe Coleman | Fourth | 5½ out |
| Sunday, May 16 |
| » Lost to Yankees (17-10), 2-0 | Memorial Stadium (7-6) | 10-14 | |
| » Starters: Allie Reynolds vs Dave Koslo | Fifth | 5½ out |
| » Defeated Yankees (17-11), 6-2 | Memorial Stadium (8-6) | 11-14 | |
| » Starters: Bob Kuzava vs Don Larsen | Fifth | 5½ out |
| Tuesday, May 18 |
| » Lost to Senators (10-17), 3-1 | Memorial Stadium (8-7) | 11-15 | |
| » Starters: Mickey McDermott vs Bob Turley | Fifth | 6½ out |
| Wednesday, May 19 |
| » Defeated Senators (10-18), 5-3 | Memorial Stadium (9-7) | 12-15 | |
| » Starters: Chuck Stobbs vs Joe Coleman | Fifth | 6½ out |
| Friday, May 21 |
| » Lost to Indians (21-10), 2-1 | Cleveland Stadium (0-1) | 12-16 | |
| » Starters: Duane Pillette vs Early Wynn | Fifth | 7½ out |
| Saturday, May 22 |
| » Lost to Indians (22-10), 4-3 | Cleveland Stadium (0-2) | 12-17 | Lost 2 |
| » Starters: Don Larsen vs Mike Garcia | Fifth | 8½ out |
| Sunday, May 23 |
| » Lost to Indians (23-10), 14-3 | Cleveland Stadium (0-3) | 12-18 | Lost 3 |
| » Starters: Lou Kretlow vs Bob Feller | Fifth | 10½ out |
| » Lost to Indians (24-10), 2-1 | Cleveland Stadium (0-4) | 12-19 | Lost 4 |
| » Starters: Bob Turley vs Art Houtteman | Fifth | 10½ out |
| Tuesday, May 25 |
| » Lost to Tigers (17-13), 5-4 | Tiger Stadium (1-2) | 12-20 | Lost 5 |
| » Starters: Joe Coleman vs Billy Hoeft | Fifth | 10½ out |
| Wednesday, May 26 |
| » Lost to Tigers (18-13), 6-3 | Tiger Stadium (1-3) | 12-21 | Lost 6 |
| » Starters: Don Larsen vs George Zuverink | Sixth | 10½ out |
| Thursday, May 27 |
| » Lost to Tigers (19-13), 7-1 | Tiger Stadium (1-4) | 12-22 | Lost 7 |
| » Starters: Duane Pillette vs Ned Garver | Sixth | 11 out |
| Friday, May 28 |
| » Lost to White Sox (25-13), 11-6 | Memorial Stadium (9-8) | 12-23 | Lost 8 |
| » Starters: Mike Fornieles vs Lou Kretlow | Seventh | 12½ out |
| » Lost to White Sox (26-13), 14-8 | Memorial Stadium (9-9) | 12-24 | Lost 9 |
| » Starters: Don Johnson vs Bob Turley | Seventh | 12½ out |
| Saturday, May 29 |
| » Lost to White Sox (27-13), 11-4 | Memorial Stadium (9-10) | 12-25 | Lost 10 |
| » Starters: Virgil Trucks vs Joe Coleman | Seventh | 13½ out |
| Sunday, May 30 |
| » Defeated White Sox (27-14), 5-2 | Memorial Stadium (10-10) | 13-25 | |
| » Starters: Al Sima vs Don Larsen | Eighth | 13½ out |
| Monday, May 31 |
| » Lost to Tigers (20-16), 7-5 | Memorial Stadium (10-11) | 13-26 | |
| » Starters: George Zuverink vs Bob Turley | Seventh | 13½ out |
| » Defeated Tigers (20-17), 4-2 | Memorial Stadium (11-11) | 14-26 | |
| » Starters: Billy Hoeft vs Duane Pillette | Seventh | 13½ out |
| Tuesday, June 1 |
| » Lost to Tigers (21-17), 4-3 | Memorial Stadium (11-12) | 14-27 | |
| » Starters: Ralph Branca vs Lou Kretlow | Eighth | 14 out |
| Wednesday, June 2 |
| » Defeated Athletics (15-28), 9-1 | Shibe Park (1-2) | 15-27 | |
| » Starters: Joe Coleman vs Arnie Portocarrero | Seventh | 14 out |
| Thursday, June 3 |
| » Lost to Athletics (16-28), 6-2 | Shibe Park (1-3) | 15-28 | |
| » Starters: Don Larsen vs Marion Fricano | Eighth | 14 out |
| Friday, June 4 |
| » Lost to Athletics (17-28), 7-6 | Shibe Park (1-4) | 15-29 | Lost 2 |
| » Starters: Bob Chakales vs Bob Trice | Eighth | 14 out |
| Saturday, June 5 |
| » Defeated Yankees (28-19), 2-1 | Yankee Stadium (1-2) | 16-29 | |
| » Starters: Bob Turley vs Harry Byrd | Eighth | 14½ out |
| » Lost to Yankees (29-19), 3-1 | Yankee Stadium (1-3) | 16-30 | |
| » Starters: Duane Pillette vs Jim McDonald | Eighth | 14½ out |
| Sunday, June 6 |
| » Defeated Yankees (29-20), 7-5 | Yankee Stadium (2-3) | 17-30 | |
| » Starters: Joe Coleman vs Bob Grim | Seventh | 15½ out |
| » Lost to Yankees (30-20), 5-2 | Yankee Stadium (2-4) | 17-31 | |
| » Starters: Don Larsen vs Allie Reynolds | Seventh | 15½ out |
| Tuesday, June 8 |
| » Defeated Red Sox (18-26), 7-4 | Fenway Park (1-0) | 18-31 | |
| » Starters: Bob Chakales vs Tex Clevenger | Seventh | 15½ out |
| Future Oriole Lenn Sakata is born in Honolulu, HI. |
| Wednesday, June 9 |
| » Lost to Red Sox (19-26), 7-6 | Fenway Park (1-1) | 18-32 | |
| » Starters: Bob Turley vs Bill Henry | Seventh | 16½ out |
| Thursday, June 10 |
| » Defeated Red Sox (19-27), 5-1 | Fenway Park (2-1) | 19-32 | |
| » Starters: Joe Coleman vs Leo Kiely | Seventh | 15½ out |
| » Defeated Red Sox (19-28), 9-0 | Fenway Park (3-1) | 20-32 | Won 2 |
| » Starters: Duane Pillette vs Tom Herrin | Seventh | 15½ out |
| Friday, June 11 |
| » Lost to Senators (22-29), 9-8 | Griffith Stadium (1-1) | 20-33 | |
| » Starters: Bob Chakales vs Johnny Schmitz | Seventh | 15½ out |
| Saturday, June 12 |
| » Defeated Senators (22-30), 7-3 | Griffith Stadium (2-1) | 21-33 | |
| » Starters: Lou Kretlow vs Chuck Stobbs | Sixth | 15 out |
| Sunday, June 13 |
| » Defeated Senators (22-31), 6-4 | Griffith Stadium (3-1) | 22-33 | Won 2 |
| » Starters: Bob Turley vs Mickey McDermott | Sixth | 16 out |
| » Lost to Senators (23-31), 4-0 | Griffith Stadium (3-2) | 22-34 | |
| » Starters: Don Larsen vs Bob Porterfield | Sixth | 16 out |
| Tuesday, June 15 |
| » Lost to Yankees (36-22), 6-4 | Memorial Stadium (11-13) | 22-35 | Lost 2 |
| » Starters: Allie Reynolds vs Joe Coleman | Seventh | 17½ out |
| Wednesday, June 16 |
| » Lost to Yankees (37-22), 2-0 | Memorial Stadium (11-14) | 22-36 | Lost 3 |
| » Starters: Whitey Ford vs Duane Pillette | Seventh | 18½ out |
| Thursday, June 17 |
| » Lost to Yankees (38-22), 9-2 | Memorial Stadium (11-15) | 22-37 | Lost 4 |
| » Starters: Jim McDonald vs Bob Turley | Seventh | 19½ out |
| Friday, June 18 |
| » Lost to Senators (24-34), 7-5 | Memorial Stadium (11-16) | 22-38 | Lost 5 |
| » Starters: Bob Porterfield vs Lou Kretlow | Seventh | 20½ out |
| Saturday, June 19 |
| » Lost to Senators (25-34), 5-2 | Memorial Stadium (11-17) | 22-39 | Lost 6 |
| » Starters: Johnny Schmitz vs Joe Coleman | Eighth | 20½ out |
| Sunday, June 20 |
| » Lost to Senators (26-34), 7-1 | Memorial Stadium (11-18) | 22-40 | Lost 7 |
| » Starters: Connie Marrero vs Duane Pillette | Eighth | 22½ out |
| » Lost to Senators (27-34), 7-2 | Memorial Stadium (11-19) | 22-41 | Lost 8 |
| » Starters: Dean Stone vs Bob Chakales | Eighth | 22½ out |
| » Major-league debuts: Billy O'Dell (Orioles) |
| Tuesday, June 22 |
| » Lost to Red Sox (22-38), 3-1 | Memorial Stadium (11-20) | 22-42 | Lost 9 |
| » Starters: Tom Brewer vs Bob Turley | Eighth | 22½ out |
| Wednesday, June 23 |
| » Defeated Red Sox (22-39), 8-7 | Memorial Stadium (12-20) | 23-42 | |
| » Starters: Frank Sullivan vs Joe Coleman | Eighth | 22½ out |
| Friday, June 25 |
| » Defeated Athletics (26-38), 5-1 | Memorial Stadium (13-20) | 24-42 | Won 2 |
| » Starters: Marion Fricano vs Duane Pillette | Seventh | 21 out |
| Saturday, June 26 |
| » Defeated Athletics (26-39), 5-4 | Memorial Stadium (14-20) | 25-42 | Won 3 |
| » Starters: Alex Kellner vs Lou Kretlow | Seventh | 20 out |
| Sunday, June 27 |
| » Defeated Athletics (26-40), 4-3 | Memorial Stadium (15-20) | 26-42 | Won 4 |
| » Starters: Bob Trice vs Bob Turley | Sixth | 19½ out |
| » Defeated Athletics (26-41), 3-2 | Memorial Stadium (16-20) | 27-42 | Won 5 |
| » Starters: Al Sima vs Joe Coleman | Sixth | 19½ out |
| Tuesday, June 29 |
| » Lost to Indians (47-22), 5-1 | Memorial Stadium (16-21) | 27-43 | |
| » Starters: Art Houtteman vs Don Larsen | Seventh | 20½ out |
| Wednesday, June 30 |
| » Lost to Indians (48-22), 2-0 | Memorial Stadium (16-22) | 27-44 | Lost 2 |
| » Starters: Mike Garcia vs Duane Pillette | Seventh | 21½ out |
| Friday, July 2 |
| » Defeated Tigers (31-38), 2-0 | Memorial Stadium (17-22) | 28-44 | |
| » Starters: Al Aber vs Joe Coleman | Seventh | 22 out |
| Saturday, July 3 |
| » Defeated Tigers (31-39), 5-3 | Memorial Stadium (18-22) | 29-44 | Won 2 |
| » Starters: Billy Hoeft vs Bob Turley | Seventh | 22 out |
| Sunday, July 4 |
| » Defeated Tigers (31-40), 3-1 | Memorial Stadium (19-22) | 30-44 | Won 3 |
| » Starters: Steve Gromek vs Lou Kretlow | Sixth | 22 out |
| Monday, July 5 |
| » Lost to White Sox (47-30), 3-0 | Comiskey Park I (1-4) | 30-45 | |
| » Starters: Don Larsen vs Billy Pierce | Sixth | 23 out |
| » Lost to White Sox (48-30), 2-1 | Comiskey Park I (1-5) | 30-46 | Lost 2 |
| » Starters: Duane Pillette vs Harry Dorish | Sixth | 23 out |
| Tuesday, July 6 |
| » Lost to Indians (54-23), 11-3 | Cleveland Stadium (0-5) | 30-47 | Lost 3 |
| » Starters: Joe Coleman vs Early Wynn | Sixth | 24 out |
| Wednesday, July 7 |
| » Lost to Indians (55-23), 6-1 | Cleveland Stadium (0-6) | 30-48 | Lost 4 |
| » Starters: Bob Turley vs Mike Garcia | Seventh | 25 out |
| Thursday, July 8 |
| » Lost to Indians (56-23), 4-1 | Cleveland Stadium (0-7) | 30-49 | Lost 5 |
| » Starters: Lou Kretlow vs Bob Feller | Seventh | 26 out |
| Friday, July 9 |
| » Defeated Tigers (33-44), 7-5 | Tiger Stadium (2-4) | 31-49 | |
| » Starters: Duane Pillette vs George Zuverink | Seventh | 25 out |
| Saturday, July 10 |
| » Lost to Tigers (34-44), 2-1 | Tiger Stadium (2-5) | 31-50 | |
| » Starters: Joe Coleman vs Ned Garver | Seventh | 25 out |
| Sunday, July 11 |
| » Lost to Tigers (35-44), 2-1 | Tiger Stadium (2-6) | 31-51 | Lost 2 |
| » Starters: Bob Turley vs Al Aber | Eighth | 24½ out |
| Thursday, July 15 |
| » Lost to Yankees (57-28), 3-1 | Yankee Stadium (2-5) | 31-52 | Lost 3 |
| » Starters: Don Larsen vs Bob Wiesler | Eighth | 25½ out |
| Friday, July 16 |
| » Lost to Yankees (58-28), 3-2 | Yankee Stadium (2-6) | 31-53 | Lost 4 |
| » Starters: Joe Coleman vs Whitey Ford | Eighth | 26½ out |
| Saturday, July 17 |
| » Lost to Yankees (59-28), 9-3 | Yankee Stadium (2-7) | 31-54 | Lost 5 |
| » Starters: Lou Kretlow vs Ed Lopat | Eighth | 27½ out |
| Sunday, July 18 |
| » Lost to Red Sox (35-49), 4-0 | Fenway Park (3-2) | 31-55 | Lost 6 |
| » Starters: Bob Turley vs Russ Kemmerer | Seventh | 27½ out |
| » Defeated Red Sox (35-50), 4-1 | Fenway Park (4-2) | 32-55 | |
| » Starters: Duane Pillette vs Bill Henry | Seventh | 27½ out |
| Monday, July 19 |
| » Lost to Red Sox (36-50), 9-7 | Fenway Park (4-3) | 32-56 | |
| » Starters: Bob Chakales vs Sid Hudson | Seventh | 29 out |
| » Lost to Red Sox (37-50), 8-5 | Fenway Park (4-4) | 32-57 | Lost 2 |
| » Starters: Don Larsen vs Leo Kiely | Seventh | 29 out |
| Tuesday, July 20 |
| » Lost to Senators (36-50), 9-1 | Griffith Stadium (3-3) | 32-58 | Lost 3 |
| » Starters: Joe Coleman vs Johnny Schmitz | Seventh | 29½ out |
| Wednesday, July 21 |
| » Lost to Senators (37-50), 6-5 | Griffith Stadium (3-4) | 32-59 | Lost 4 |
| » Starters: Bob Turley vs Dean Stone | Seventh | 30 out |
| Thursday, July 22 |
| » Lost to Senators (38-50), 3-2 | Griffith Stadium (3-5) | 32-60 | Lost 5 |
| » Starters: Bob Chakales vs Bob Porterfield | Eighth | 31½ out |
| Friday, July 23 |
| » Defeated Athletics (31-58), 7-5 | Shibe Park (2-4) | 33-60 | |
| » Starters: Duane Pillette vs Alex Kellner | Seventh | 31½ out |
| Saturday, July 24 |
| » Lost to Athletics (32-58), 6-5 | Shibe Park (2-5) | 33-61 | |
| » Starters: Joe Coleman vs Johnny Gray | Eighth | 32½ out |
| Sunday, July 25 |
| » Lost to Athletics (33-58), 9-4 | Shibe Park (2-6) | 33-62 | Lost 2 |
| » Starters: Bob Turley vs Arnie Portocarrero | Eighth | 33 out |
| » Lost to Athletics (34-58), 6-4 | Shibe Park (2-7) | 33-63 | Lost 3 |
| » Starters: Don Larsen vs Sonny Dixon | Eighth | 33 out |
| Tuesday, July 27 |
| » Defeated Senators (41-51), 7-5 | Memorial Stadium (20-22) | 34-63 | |
| » Starters: Johnny Schmitz vs Duane Pillette | Eighth | 33 out |
| Wednesday, July 28 |
| » Defeated Senators (41-52), 2-1 | Memorial Stadium (21-22) | 35-63 | Won 2 |
| » Starters: Bob Porterfield vs Joe Coleman | Eighth | 33 out |
| Thursday, July 29 |
| » Lost to Senators (42-52), 6-0 | Memorial Stadium (21-23) | 35-64 | |
| » Starters: Chuck Stobbs vs Billy O'Dell | Eighth | 33 out |
| Friday, July 30 |
| » Defeated Yankees (67-34), 10-0 | Memorial Stadium (22-23) | 36-64 | |
| » Starters: Allie Reynolds vs Don Larsen | Seventh | 33 out |
| Saturday, July 31 |
| » Lost to Yankees (68-34), 6-5 | Memorial Stadium (22-24) | 36-65 | |
| » Starters: Bob Grim vs Bob Turley | Seventh | 34 out |
| Sunday, August 1 |
| » Lost to Yankees (69-34), 8-6 | Memorial Stadium (22-25) | 36-66 | Lost 2 |
| » Starters: Harry Byrd vs Duane Pillette | Seventh | 36 out |
| » Lost to Yankees (70-34), 2-1 | Memorial Stadium (22-26) | 36-67 | Lost 3 |
| » Starters: Ralph Branca vs Joe Coleman | Seventh | 36 out |
| Monday, August 2 |
| » Defeated Athletics (35-67), 10-2 | Memorial Stadium (23-26) | 37-67 | |
| » Starters: Johnny Gray vs Bob Turley | Seventh | 35½ out |
| Tuesday, August 3 |
| » Lost to Athletics (36-67), 6-2 | Memorial Stadium (23-27) | 37-68 | |
| » Starters: Arnie Portocarrero vs Don Larsen | Seventh | 35½ out |
| Wednesday, August 4 |
| » Lost to Athletics (37-67), 6-4 | Memorial Stadium (23-28) | 37-69 | Lost 2 |
| » Starters: Alex Kellner vs Duane Pillette | Eighth | 36½ out |
| Friday, August 6 |
| » Lost to Red Sox (42-61), 3-1 | Memorial Stadium (23-29) | 37-70 | Lost 3 |
| » Starters: Willard Nixon vs Joe Coleman | Eighth | 37 out |
| Saturday, August 7 |
| » Defeated Red Sox (42-62), 2-1 | Memorial Stadium (24-29) | 38-70 | |
| » Starters: Mel Parnell vs Bob Turley | Seventh | 37 out |
| Sunday, August 8 |
| » Lost to Red Sox (43-62), 4-2 | Memorial Stadium (24-30) | 38-71 | |
| » Starters: Russ Kemmerer vs Duane Pillette | Seventh | 39 out |
| » Lost to Red Sox (44-62), 4-1 | Memorial Stadium (24-31) | 38-72 | Lost 2 |
| » Starters: Frank Sullivan vs Don Larsen | Seventh | 39 out |
| Tuesday, August 10 |
| » Defeated White Sox (71-42), 3-1 | Comiskey Park I (2-5) | 39-72 | |
| » Starters: Lou Kretlow vs Bob Keegan | Seventh | 38 out |
| Wednesday, August 11 |
| » Lost to White Sox (72-42), 1-0 | Comiskey Park I (2-6) | 39-73 | |
| » Starters: Bob Kuzava vs Virgil Trucks | Seventh | 39 out |
| Friday, August 13 |
| » Lost to Indians (79-33), 9-4 | Cleveland Stadium (0-8) | 39-74 | Lost 2 |
| » Starters: Bob Turley vs Bob Feller | Seventh | 40½ out |
| Saturday, August 14 |
| » Lost to Indians (80-33), 4-3 | Cleveland Stadium (0-9) | 39-75 | Lost 3 |
| » Starters: Don Larsen vs Early Wynn | Seventh | 41½ out |
| Sunday, August 15 |
| » Lost to Indians (81-33), 5-2 | Cleveland Stadium (0-10) | 39-76 | Lost 4 |
| » Starters: Joe Coleman vs Art Houtteman | Eighth | 43½ out |
| » Lost to Indians (82-33), 3-1 | Cleveland Stadium (0-11) | 39-77 | Lost 5 |
| » Starters: Lou Kretlow vs Mike Garcia | Eighth | 43½ out |
| Tuesday, August 17 |
| » Lost to White Sox (75-44), 2-0 | Memorial Stadium (24-32) | 39-78 | Lost 6 |
| » Starters: Billy Pierce vs Bob Turley | Eighth | 45 out |
| » Lost to White Sox (76-44), 3-1 | Memorial Stadium (24-33) | 39-79 | Lost 7 |
| » Starters: Don Johnson vs Bob Kuzava | Eighth | 45 out |
| Wednesday, August 18 |
| » Lost to White Sox (77-44), 4-1 | Memorial Stadium (24-34) | 39-80 | Lost 8 |
| » Starters: Sandy Consuegra vs Don Larsen | Seventh | 46 out |
| Thursday, August 19 |
| » Lost to White Sox (78-44), 4-3 | Memorial Stadium (24-35) | 39-81 | Lost 9 |
| » Starters: Jack Harshman vs Lou Kretlow | Eighth | 46½ out |
| Friday, August 20 |
| » Lost to Indians (86-34), 7-2 | Memorial Stadium (24-36) | 39-82 | Lost 10 |
| » Starters: Art Houtteman vs Joe Coleman | Eighth | 47½ out |
| Saturday, August 21 |
| » Lost to Indians (87-34), 4-1 | Memorial Stadium (24-37) | 39-83 | Lost 11 |
| » Starters: Bob Lemon vs Bob Turley | Eighth | 48½ out |
| Sunday, August 22 |
| » Lost to Indians (88-34), 12-1 | Memorial Stadium (24-38) | 39-84 | Lost 12 |
| » Starters: Early Wynn vs Bob Kuzava | Eighth | 49½ out |
| Tuesday, August 24 |
| » Lost to Yankees (84-40), 9-2 | Yankee Stadium (2-8) | 39-85 | Lost 13 |
| » Starters: Don Larsen vs Whitey Ford | Eighth | 49½ out |
| Wednesday, August 25 |
| » Lost to Yankees (85-40), 5-1 | Yankee Stadium (2-9) | 39-86 | Lost 14 |
| » Starters: Joe Coleman vs Ed Lopat | Eighth | 50½ out |
| Thursday, August 26 |
| » Defeated Red Sox (54-69), 5-3 | Fenway Park (5-4) | 40-86 | |
| » Starters: Bob Turley vs Sid Hudson | Eighth | 50½ out |
| Friday, August 27 |
| » Lost to Red Sox (55-69), 3-2 | Fenway Park (5-5) | 40-87 | |
| » Starters: Lou Kretlow vs Russ Kemmerer | Eighth | 50½ out |
| Saturday, August 28 |
| » Lost to Red Sox (56-69), 3-2 | Fenway Park (5-6) | 40-88 | Lost 2 |
| » Starters: Don Larsen vs Mel Parnell | Eighth | 51½ out |
| Sunday, August 29 |
| » Defeated Senators (52-74), 8-4 | Griffith Stadium (4-5) | 41-88 | |
| » Starters: Bob Kuzava vs Bob Porterfield | Eighth | 51½ out |
| » Defeated Senators (52-75), 5-0 | Griffith Stadium (5-5) | 42-88 | Won 2 |
| » Starters: Joe Coleman vs Gus Keriazakos | Eighth | 51½ out |
| Monday, August 30 |
| » Defeated Senators (52-76), 3-1 | Griffith Stadium (6-5) | 43-88 | Won 3 |
| » Starters: Bob Turley vs Dean Stone | Seventh | 51½ out |
| Tuesday, August 31 |
| » Lost to Athletics (43-87), 8-6 | Shibe Park (2-8) | 43-89 | |
| » Starters: Lou Kretlow vs Charlie Bishop | Eighth | 53 out |
| » Lost to Athletics (44-87), 6-3 | Shibe Park (2-9) | 43-90 | Lost 2 |
| » Starters: Don Larsen vs Johnny Gray | Eighth | 53 out |
| Friday, September 3 |
| » Lost to Tigers (58-75), 4-3 | Tiger Stadium (2-7) | 43-91 | Lost 3 |
| » Starters: Bob Turley vs Steve Gromek | Eighth | 53 out |
| Saturday, September 4 |
| » Lost to Tigers (59-75), 7-4 | Tiger Stadium (2-8) | 43-92 | Lost 4 |
| » Starters: Joe Coleman vs Al Aber | Eighth | 53 out |
| Sunday, September 5 |
| » Defeated Tigers (59-76), 4-3 | Tiger Stadium (3-8) | 44-92 | |
| » Starters: Lou Kretlow vs Bob Miller | Eighth | 53 out |
| Monday, September 6 |
| » Lost to Indians (98-39), 6-1 | Memorial Stadium (24-39) | 44-93 | |
| » Starters: Bob Lemon vs Duane Pillette | Eighth | 53 out |
| » Defeated Indians (98-40), 3-2 | Memorial Stadium (25-39) | 45-93 | |
| » Starters: Mike Garcia vs Don Larsen | Eighth | 53 out |
| Wednesday, September 8 |
| » Lost to Yankees (94-44), 8-2 | Memorial Stadium (25-40) | 45-94 | |
| » Starters: Tommy Byrne vs Bob Turley | Eighth | 54 out |
| Future Oriole Don Aase is born in Orange, CA. |
| Thursday, September 9 |
| » Defeated Yankees (94-45), 1-0 | Memorial Stadium (26-40) | 46-94 | |
| » Starters: Tom Morgan vs Joe Coleman | Seventh | 54 out |
| Friday, September 10 |
| » Defeated Senators (60-80), 4-3 | Memorial Stadium (27-40) | 47-94 | Won 2 |
| » Starters: Mickey McDermott vs Lou Kretlow | Seventh | 54 out |
| Saturday, September 11 |
| » Lost to Senators (61-80), 3-0 | Memorial Stadium (27-41) | 47-95 | |
| » Starters: Dean Stone vs Don Larsen | Seventh | 55 out |
| Sunday, September 12 |
| » Defeated Athletics (47-96), 4-3 | Memorial Stadium (28-41) | 48-95 | |
| » Starters: Johnny Gray vs Bob Turley | Seventh | 56 out |
| » Lost to Athletics (48-96), 5-4 | Memorial Stadium (28-42) | 48-96 | |
| » Starters: Al Sima vs Duane Pillette | Seventh | 56 out |
| Tuesday, September 14 |
| » Defeated Red Sox (63-80), 3-1 | Memorial Stadium (29-42) | 49-96 | |
| » Starters: Willard Nixon vs Joe Coleman | Seventh | 56 out |
| Wednesday, September 15 |
| » Defeated Red Sox (63-81), 2-1 | Memorial Stadium (30-42) | 50-96 | Won 2 |
| » Starters: Mel Parnell vs Lou Kretlow | Seventh | 55½ out |
| Friday, September 17 |
| » Defeated White Sox (91-56), 5-1 | Comiskey Park I (3-6) | 51-96 | Won 3 |
| » Starters: Bob Turley vs Jack Harshman | Seventh | 55½ out |
| Future Oriole Wayne Krenchicki is born in Trenton, NJ. |
| Saturday, September 18 |
| » Lost to White Sox (92-56), 6-2 | Comiskey Park I (3-7) | 51-97 | |
| » Starters: Don Larsen vs Billy Pierce | Sixth | 56½ out |
| Sunday, September 19 |
| » Defeated White Sox (92-57), 5-1 | Comiskey Park I (4-7) | 52-97 | |
| » Starters: Duane Pillette vs Virgil Trucks | Seventh | 56½ out |
| Monday, September 20 |
| » Lost to Tigers (65-84), 4-3 | Memorial Stadium (30-43) | 52-98 | |
| » Starters: George Zuverink vs Joe Coleman | Seventh | 57½ out |
| Tuesday, September 21 |
| » Defeated Tigers (65-85), 4-3 | Memorial Stadium (31-43) | 53-98 | |
| » Starters: Ned Garver vs Bob Turley | Seventh | 56½ out |
| Wednesday, September 22 |
| » Lost to Tigers (66-85), 4-1 | Memorial Stadium (31-44) | 53-99 | |
| » Starters: Steve Gromek vs Lou Kretlow | Seventh | 57½ out |
| Friday, September 24 |
| » Defeated White Sox (93-60), 2-1 | Memorial Stadium (32-44) | 54-99 | |
| » Starters: Virgil Trucks vs Billy O'Dell | Sixth | 56½ out |
| Saturday, September 25 |
| » Lost to White Sox (94-60), 11-0 | Memorial Stadium (32-45) | 54-100 | |
| » Starters: Billy Pierce vs Don Larsen | Seventh | 57½ out |
| » Major-league debuts: Ryne Duren (Orioles) |
| Friday, October 22 |
| Future Oriole Jamie Quirk is born in Whittier, CA. |
| Monday, October 25 |
| Future Oriole Tito Landrum is born in Joplin, MO. |
| Thursday, October 28 |
| Future Oriole Sammy Stewart is born in Asheville, NC. |
| Tuesday, November 30 |
| Future Oriole Joe Kerrigan is born in Philadelphia, PA. |
| Sunday, December 5 |
| Future Oriole Gary Roenicke is born in Covina, CA. |
| Monday, December 6 |
| Future Oriole Mike Parrott is born in Oxnard, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |
