| Tuesday, January 5 |
| Future Cardinal John Littlefield is born in Covina, CA. Former Cardinal Rabbit Maranville dies in New York, NY at the age of 63 |
| Tuesday, February 2 |
| Future Cardinal Rob Dressler is born in Portland, OR. Future Cardinal John Tudor is born in Schenectady, NY. |
| Wednesday, February 10 |
| Future Cardinal Larry McWilliams is born in Wichita, KS. |
| Saturday, February 13 |
| Future Cardinal Donnie Moore is born in Lubbock, TX. |
| Monday, February 22 |
| Former Cardinal Owen Wilson dies in Bertram, TX at the age of 71. |
| Monday, March 29 |
| Future Cardinal Mike Ramsey is born in Roanoke, VA. |
| Tuesday, April 13 |
| » Lost to Cubs (1-0), 13-4 | Sportsman's Park III (0-1) | 0-1 | |
| » Starters: Paul Minner vs Harvey Haddix | Second | 1 out |
| » Major-league debuts: Tom Alston, Alex Grammas and Wally Moon (Cardinals) |
| Wednesday, April 14 |
| » Major-league debuts: Bob Purkey (Pirates) |
| Thursday, April 15 |
| » Lost to Braves (1-1), 7-6 | County Stadium (0-1) | 0-2 | Lost 2 |
| » Starters: Vic Raschi vs Warren Spahn | Fifth | 2 out |
| Saturday, April 17 |
| » Lost to Cubs (2-1), 23-13 | Wrigley Field (0-1) | 0-3 | Lost 3 |
| » Starters: Gerry Staley vs Johnny Klippstein | Third | 2 out |
| » Major-league debuts: Mel Wright (Cardinals) |
| Future Cardinal Denny Walling is born in Neptune, NJ. |
| Sunday, April 18 |
| » Defeated Cubs (2-2), 6-4 | Wrigley Field (1-1) | 1-3 | |
| » Starters: Vic Raschi vs Paul Minner | Fourth | 2½ out |
| » Major-league debuts: Jim Davis (Cubs) |
| Monday, April 19 |
| » Defeated Reds (4-2), 6-3 | Sportsman's Park III (1-1) | 2-3 | Won 2 |
| » Starters: Harry Perkowski vs Harvey Haddix | Fourth | 1½ out |
| Tuesday, April 20 |
| » Lost to Reds (5-2), 13-6 | Sportsman's Park III (1-2) | 2-4 | |
| » Starters: Ken Raffensberger vs Memo Luna | Fifth | 2½ out |
| » Major-league debuts: Memo Luna (Cardinals) |
| Wednesday, April 21 |
| » Defeated Reds (5-3), 4-2 | Crosley Field (1-0) | 3-4 | |
| » Starters: Gerry Staley vs Corky Valentine | Fourth | 1½ out |
| Friday, April 23 |
| » Lost to Braves (4-3), 7-5 | Sportsman's Park III (1-3) | 3-5 | |
| » Starters: Gene Conley vs Vic Raschi | Sixth | 2 out |
| Saturday, April 24 |
| » Defeated Braves (4-4), 7-3 | Sportsman's Park III (2-3) | 4-5 | |
| » Starters: Lew Burdette vs Harvey Haddix | Fifth | 2 out |
| Sunday, April 25 |
| » Defeated Braves (4-5), 7-6 | Sportsman's Park III (3-3) | 5-5 | Won 2 |
| » Starters: Warren Spahn vs Stu Miller | Fourth | 1½ out |
| Tuesday, April 27 |
| » Defeated Dodgers (7-5), 7-3 | Sportsman's Park III (4-3) | 6-5 | Won 3 |
| » Starters: Preacher Roe vs Gerry Staley | Third | 1 out |
| Wednesday, April 28 |
| » Defeated Dodgers (7-6), 6-5 | Sportsman's Park III (5-3) | 7-5 | Won 4 |
| » Starters: Billy Loes vs Vic Raschi | Second | 1 out |
| » Major-league debuts: Tim Thompson (Dodgers) |
| Thursday, April 29 |
| » Lost to Pirates (6-10), 4-3 | Sportsman's Park III (5-4) | 7-6 | |
| » Starters: Bob Purkey vs Harvey Haddix | Third | 1 out |
| Saturday, May 1 |
| » Defeated Pirates (6-11), 5-4 | Sportsman's Park III (6-4) | 8-6 | |
| » Starters: George O'Donnell vs Stu Miller | Second | 1½ out |
| Sunday, May 2 |
| » Defeated Giants (8-8), 10-6 | Sportsman's Park III (7-4) | 9-6 | Won 2 |
| » Starters: Johnny Antonelli vs Gerry Staley | Second | ½ out |
| » Lost to Giants (9-8), 9-7 | Sportsman's Park III (7-5) | 9-7 | |
| » Starters: Don Liddle vs Joe Presko | Second | ½ out |
| » Major-league debuts: Joey Amalfitano (Giants) |
| Monday, May 3 |
| » Defeated Giants (9-9), 8-2 | Sportsman's Park III (8-5) | 10-7 | |
| » Starters: Ruben Gomez vs Vic Raschi | Second | 1 out |
| Tuesday, May 4 |
| » Lost to Phillies (10-6), 14-10 | Sportsman's Park III (8-6) | 10-8 | |
| » Starters: Robin Roberts vs Harvey Haddix | Third | 1 out |
| Wednesday, May 5 |
| » Lost to Phillies (11-6), 10-3 | Sportsman's Park III (8-7) | 10-9 | Lost 2 |
| » Starters: Robin Roberts vs Tom Poholsky | Fourth | 2 out |
| Friday, May 7 |
| » Lost to Reds (13-8), 10-3 | Crosley Field (1-1) | 10-10 | Lost 3 |
| » Starters: Gerry Staley vs Corky Valentine | Fifth | 2½ out |
| Saturday, May 8 |
| » Defeated Reds (13-9), 7-3 | Crosley Field (2-1) | 11-10 | |
| » Starters: Harvey Haddix vs Art Fowler | Fourth | 1½ out |
| Sunday, May 9 |
| » Defeated Reds (13-10), 10-7 | Crosley Field (3-1) | 12-10 | Won 2 |
| » Starters: Vic Raschi vs Howie Judson | Fourth | 2 out |
| » Lost to Reds (14-10), 6-5 | Crosley Field (3-2) | 12-11 | |
| » Starters: Stu Miller vs Bud Podbielan | Fourth | 2 out |
| Wednesday, May 12 |
| » Defeated Pirates (7-18), 13-5 | Forbes Field (1-0) | 13-11 | |
| » Starters: Harvey Haddix vs George O'Donnell | Third | 1 out |
| Thursday, May 13 |
| » Lost to Dodgers (14-10), 10-3 | Ebbets Field (0-1) | 13-12 | |
| » Starters: Gerry Staley vs Johnny Podres | Fifth | 2 out |
| Friday, May 14 |
| » Defeated Dodgers (14-11), 10-1 | Ebbets Field (1-1) | 14-12 | |
| » Starters: Vic Raschi vs Billy Loes | Fourth | 1 out |
| Saturday, May 15 |
| » Lost to Dodgers (15-11), 1-0 | Ebbets Field (1-2) | 14-13 | |
| » Starters: Tom Poholsky vs Carl Erskine | Fourth | 2 out |
| Sunday, May 16 |
| » Defeated Phillies (15-11), 7-3 | Shibe Park (1-0) | 15-13 | |
| » Starters: Harvey Haddix vs Steve Ridzik | Fourth | 2 out |
| » Lost to Phillies (16-11), 8-4 | Shibe Park (1-1) | 15-14 | |
| » Starters: Carl Scheib vs Paul Penson | Fourth | 2 out |
| Monday, May 17 |
| » Defeated Phillies (16-12), 8-0 | Shibe Park (2-1) | 16-14 | |
| » Starters: Joe Presko vs Robin Roberts | Third | 1 out |
| Tuesday, May 18 |
| » Defeated Giants (16-14), 9-3 | Polo Grounds V (1-0) | 17-14 | Won 2 |
| » Starters: Gerry Staley vs Larry Jansen | Second | 1 out |
| Wednesday, May 19 |
| » Defeated Giants (16-15), 3-0 | Polo Grounds V (2-0) | 18-14 | Won 3 |
| » Starters: Vic Raschi vs Sal Maglie | First | -- |
| Thursday, May 20 |
| » Defeated Pirates (11-23), 17-4 | Forbes Field (2-0) | 19-14 | Won 4 |
| » Starters: Tom Poholsky vs Bob Purkey | First | -- |
| Friday, May 21 |
| » Defeated Reds (17-17), 8-7 | Sportsman's Park III (9-7) | 20-14 | Won 5 |
| » Starters: Fred Baczewski vs Harvey Haddix | First | -- |
| Saturday, May 22 |
| » Lost to Reds (18-17), 4-2 | Sportsman's Park III (9-8) | 20-15 | |
| » Starters: Art Fowler vs Joe Presko | First | -- |
| Sunday, May 23 |
| » Lost to Reds (19-17), 13-6 | Sportsman's Park III (9-9) | 20-16 | Lost 2 |
| » Starters: Harry Perkowski vs Gerry Staley | Second | 1 out |
| Monday, May 24 |
| » Lost to Cubs (15-19), 6-2 | Sportsman's Park III (9-10) | 20-17 | Lost 3 |
| » Starters: Jim Davis vs Vic Raschi | Fourth | 1½ out |
| Tuesday, May 25 |
| » Defeated Cubs (15-20), 9-4 | Sportsman's Park III (10-10) | 21-17 | |
| » Starters: Johnny Klippstein vs Harvey Haddix | Fourth | 1½ out |
| Wednesday, May 26 |
| » Lost to Cubs (16-20), 15-5 | Sportsman's Park III (10-11) | 21-18 | |
| » Starters: Paul Minner vs Tom Poholsky | Fourth | 2½ out |
| Thursday, May 27 |
| » Lost to Cubs (17-20), 7-3 | Sportsman's Park III (10-12) | 21-19 | Lost 2 |
| » Starters: Bob Rush vs Gerry Staley | Fifth | 3 out |
| Friday, May 28 |
| » Lost to Braves (23-14), 3-2 | County Stadium (0-2) | 21-20 | Lost 3 |
| » Starters: Vic Raschi vs Lew Burdette | Sixth | 4 out |
| Saturday, May 29 |
| » Defeated Braves (23-15), 12-7 | County Stadium (1-2) | 22-20 | |
| » Starters: Stu Miller vs Chet Nichols | Fifth | 3 out |
| Sunday, May 30 |
| » Defeated Braves (23-16), 3-2 | County Stadium (2-2) | 23-20 | Won 2 |
| » Starters: Harvey Haddix vs Warren Spahn | Third | 2 out |
| Monday, May 31 |
| » Lost to Cubs (20-22), 14-4 | Wrigley Field (1-2) | 23-21 | |
| » Starters: Bill Greason vs Paul Minner | Fifth | 2½ out |
| Thursday, June 3 |
| » Lost to Giants (24-19), 13-8 | Sportsman's Park III (10-13) | 23-22 | Lost 2 |
| » Starters: Sal Maglie vs Gerry Staley | Fifth | 3 out |
| Friday, June 4 |
| » Defeated Phillies (23-20), 5-2 | Sportsman's Park III (11-13) | 24-22 | |
| » Starters: Robin Roberts vs Harvey Haddix | Fifth | 3 out |
| Saturday, June 5 |
| » Lost to Phillies (24-20), 9-4 | Sportsman's Park III (11-14) | 24-23 | |
| » Starters: Murry Dickson vs Vic Raschi | Fifth | 4½ out |
| Sunday, June 6 |
| » Lost to Phillies (25-20), 11-8 | Sportsman's Park III (11-15) | 24-24 | Lost 2 |
| » Starters: Curt Simmons vs Bill Greason | Fourth | 5½ out |
| Monday, June 7 |
| » Lost to Dodgers (30-18), 7-5 | Sportsman's Park III (11-16) | 24-25 | Lost 3 |
| » Starters: Preacher Roe vs Gerry Staley | Fifth | 6½ out |
| Tuesday, June 8 |
| » Defeated Dodgers (30-19), 10-3 | Sportsman's Park III (12-16) | 25-25 | |
| » Starters: Carl Erskine vs Tom Poholsky | Fifth | 5½ out |
| Former Cardinal Tom O'Hara dies in Denver, CO at the age of 69. |
| Wednesday, June 9 |
| » Defeated Dodgers (30-20), 3-0 | Sportsman's Park III (13-16) | 26-25 | Won 2 |
| » Starters: Johnny Podres vs Harvey Haddix | Fourth | 4½ out |
| Thursday, June 10 |
| » Lost to Dodgers (31-20), 7-4 | Sportsman's Park III (13-17) | 26-26 | |
| » Starters: Russ Meyer vs Vic Raschi | Fifth | 5½ out |
| Friday, June 11 |
| » Lost to Pirates (17-38), 8-5 | Sportsman's Park III (13-18) | 26-27 | Lost 2 |
| » Starters: Vern Law vs Joe Presko | Fifth | 6½ out |
| Saturday, June 12 |
| » Lost to Pirates (18-38), 4-2 | Sportsman's Park III (13-19) | 26-28 | Lost 3 |
| » Starters: Dick Littlefield vs Gerry Staley | Fifth | 6½ out |
| Sunday, June 13 |
| » Defeated Pirates (18-39), 5-0 | Sportsman's Park III (14-19) | 27-28 | |
| » Starters: George O'Donnell vs Harvey Haddix | Third | 6½ out |
| » Defeated Pirates (18-40), 5-3 | Sportsman's Park III (15-19) | 28-28 | Won 2 |
| » Starters: Bob Purkey vs Tom Poholsky | Third | 6½ out |
| Tuesday, June 15 |
| » Defeated Phillies (28-25), 3-1 | Shibe Park (3-1) | 29-28 | Won 3 |
| » Starters: Vic Raschi vs Bob Miller | Fifth | 6½ out |
| Thursday, June 17 |
| » Lost to Phillies (29-25), 3-2 | Shibe Park (3-2) | 29-29 | |
| » Starters: Gerry Staley vs Robin Roberts | Fifth | 8 out |
| Friday, June 18 |
| » Defeated Giants (37-22), 5-0 | Polo Grounds V (3-0) | 30-29 | |
| » Starters: Harvey Haddix vs Sal Maglie | Fifth | 7 out |
| Saturday, June 19 |
| » Lost to Giants (38-22), 5-2 | Polo Grounds V (3-1) | 30-30 | |
| » Starters: Tom Poholsky vs Don Liddle | Fifth | 8 out |
| Sunday, June 20 |
| » Lost to Giants (39-22), 7-6 | Polo Grounds V (3-2) | 30-31 | Lost 2 |
| » Starters: Vic Raschi vs Ruben Gomez | Fifth | 9 out |
| Monday, June 21 |
| » Lost to Giants (40-22), 8-5 | Polo Grounds V (3-3) | 30-32 | Lost 3 |
| » Starters: Gerry Staley vs Jim Hearn | Sixth | 10 out |
| Wednesday, June 23 |
| » Defeated Pirates (21-43), 7-1 | Forbes Field (3-0) | 31-32 | |
| » Starters: Harvey Haddix vs Dick Littlefield | Fifth | 9½ out |
| Thursday, June 24 |
| » Defeated Pirates (21-44), 5-1 | Forbes Field (4-0) | 32-32 | Won 2 |
| » Starters: Brooks Lawrence vs Vern Law | Fifth | 9½ out |
| » Major-league debuts: Brooks Lawrence (Cardinals) |
| Friday, June 25 |
| » Lost to Dodgers (42-24), 3-1 | Ebbets Field (1-3) | 32-33 | |
| » Starters: Vic Raschi vs Carl Erskine | Fifth | 10½ out |
| Future Cardinal Bob Shirley is born in Cushing, OK. |
| Saturday, June 26 |
| » Lost to Dodgers (43-24), 7-6 | Ebbets Field (1-4) | 32-34 | Lost 2 |
| » Starters: Gerry Staley vs Billy Loes | Fifth | 11½ out |
| Sunday, June 27 |
| » Lost to Dodgers (44-24), 8-6 | Ebbets Field (1-5) | 32-35 | Lost 3 |
| » Starters: Harvey Haddix vs Preacher Roe | Sixth | 12½ out |
| Tuesday, June 29 |
| » Lost to Reds (34-35), 11-4 | Crosley Field (3-3) | 32-36 | Lost 4 |
| » Starters: Ralph Beard vs Joe Nuxhall | Sixth | 13½ out |
| Future Cardinal Rick Honeycutt is born in Chattanooga, TN. |
| Wednesday, June 30 |
| » Defeated Reds (34-36), 11-3 | Crosley Field (4-3) | 33-36 | |
| » Starters: Brooks Lawrence vs Art Fowler | Sixth | 13½ out |
| » Major-league debuts: Joe Cunningham (Cardinals) |
| Thursday, July 1 |
| » Defeated Braves (34-35), 9-2 | County Stadium (3-2) | 34-36 | Won 2 |
| » Starters: Harvey Haddix vs Warren Spahn | Fifth | 13½ out |
| Friday, July 2 |
| » Lost to Cubs (25-43), 7-6 | Wrigley Field (1-3) | 34-37 | |
| » Starters: Vic Raschi vs Howie Pollet | Fifth | 14½ out |
| Saturday, July 3 |
| » Lost to Cubs (26-43), 4-1 | Wrigley Field (1-4) | 34-38 | Lost 2 |
| » Starters: Ralph Beard vs Warren Hacker | Sixth | 14½ out |
| Sunday, July 4 |
| » Lost to Cubs (27-43), 4-2 | Wrigley Field (1-5) | 34-39 | Lost 3 |
| » Starters: Joe Presko vs Paul Minner | Sixth | 14½ out |
| » Defeated Cubs (27-44), 7-0 | Wrigley Field (2-5) | 35-39 | |
| » Starters: Royce Lint vs Johnny Klippstein | Sixth | 14½ out |
| Monday, July 5 |
| » Lost to Braves (37-37), 8-6 | Sportsman's Park III (15-20) | 35-40 | |
| » Starters: Jim Wilson vs Brooks Lawrence | Sixth | 16½ out |
| » Lost to Braves (38-37), 10-4 | Sportsman's Park III (15-21) | 35-41 | Lost 2 |
| » Starters: Warren Spahn vs Vic Raschi | Sixth | 16½ out |
| Tuesday, July 6 |
| » Defeated Reds (38-39), 6-0 | Sportsman's Park III (16-21) | 36-41 | |
| » Starters: Harry Perkowski vs Gerry Staley | Sixth | 16½ out |
| Wednesday, July 7 |
| » Defeated Reds (38-40), 5-4 | Sportsman's Park III (17-21) | 37-41 | Won 2 |
| » Starters: Fred Baczewski vs Brooks Lawrence | Sixth | 16½ out |
| Thursday, July 8 |
| » Defeated Reds (38-41), 2-1 | Sportsman's Park III (18-21) | 38-41 | Won 3 |
| » Starters: Joe Nuxhall vs Harvey Haddix | Fifth | 16½ out |
| Friday, July 9 |
| » Lost to Cubs (29-48), 6-4 | Sportsman's Park III (18-22) | 38-42 | |
| » Starters: Paul Minner vs Royce Lint | Sixth | 17½ out |
| Saturday, July 10 |
| » Defeated Cubs (29-49), 2-1 | Sportsman's Park III (19-22) | 39-42 | |
| » Starters: Bob Rush vs Vic Raschi | Sixth | 16½ out |
| Sunday, July 11 |
| » Defeated Cubs (29-50), 4-3 | Sportsman's Park III (20-22) | 40-42 | Won 2 |
| » Starters: Howie Pollet vs Gerry Staley | Sixth | 16 out |
| Thursday, July 15 |
| » Lost to Giants (58-27), 4-0 | Sportsman's Park III (20-23) | 40-43 | |
| » Starters: Don Liddle vs Harvey Haddix | Fifth | 17 out |
| Friday, July 16 |
| » Defeated Giants (58-28), 5-4 | Sportsman's Park III (21-23) | 41-43 | |
| » Starters: Sal Maglie vs Vic Raschi | Sixth | 16 out |
| Saturday, July 17 |
| » Lost to Giants (59-28), 10-9 | Sportsman's Park III (21-24) | 41-44 | |
| » Starters: Johnny Antonelli vs Royce Lint | Sixth | 17 out |
| Sunday, July 18 |
| » Lost to Phillies (42-41), 11-10 | Sportsman's Park III (21-25) | 41-45 | Lost 2 |
| » Starters: Murry Dickson vs Gerry Staley | Sixth | 17½ out |
| » Cardinals forfeited to Phillies. | Sportsman's Park III (21-26) | 41-46 | Lost 3 |
| Monday, July 19 |
| » Defeated Phillies (42-42), 5-1 | Sportsman's Park III (22-26) | 42-46 | |
| » Starters: Bob Greenwood vs Brooks Lawrence | Sixth | 16½ out |
| Tuesday, July 20 |
| » Defeated Phillies (42-43), 4-2 | Sportsman's Park III (23-26) | 43-46 | Won 2 |
| » Starters: Curt Simmons vs Harvey Haddix | Sixth | 16½ out |
| Wednesday, July 21 |
| » Defeated Pirates (29-62), 13-12 | Sportsman's Park III (24-26) | 44-46 | Won 3 |
| » Starters: Jake Thies vs Tom Poholsky | Sixth | 16½ out |
| Thursday, July 22 |
| » Defeated Pirates (29-63), 3-2 | Sportsman's Park III (25-26) | 45-46 | Won 4 |
| » Starters: Bob Purkey vs Ralph Beard | Fourth | 15½ out |
| Friday, July 23 |
| » Defeated Dodgers (56-38), 6-4 | Sportsman's Park III (26-26) | 46-46 | Won 5 |
| » Starters: Russ Meyer vs Vic Raschi | Fourth | 14½ out |
| Saturday, July 24 |
| » Lost to Dodgers (57-38), 7-6 | Sportsman's Park III (26-27) | 46-47 | |
| » Starters: Erv Palica vs Brooks Lawrence | Fourth | 14½ out |
| Sunday, July 25 |
| » Lost to Dodgers (58-38), 2-1 | Sportsman's Park III (26-28) | 46-48 | Lost 2 |
| » Starters: Clem Labine vs Harvey Haddix | Fifth | 14½ out |
| Tuesday, July 27 |
| » Defeated Giants (62-36), 7-4 | Polo Grounds V (4-3) | 47-48 | |
| » Starters: Ralph Beard vs Jim Hearn | Fourth | 13 out |
| Wednesday, July 28 |
| » Lost to Giants (63-36), 10-0 | Polo Grounds V (4-4) | 47-49 | |
| » Starters: Tom Poholsky vs Johnny Antonelli | Fourth | 14 out |
| Thursday, July 29 |
| » Defeated Giants (63-37), 8-0 | Polo Grounds V (5-4) | 48-49 | |
| » Starters: Vic Raschi vs Don Liddle | Fourth | 13 out |
| Friday, July 30 |
| » Defeated Phillies (46-50), 12-3 | Shibe Park (4-2) | 49-49 | Won 2 |
| » Starters: Harvey Haddix vs Bob Miller | Fourth | 13 out |
| Saturday, July 31 |
| » Defeated Phillies (46-51), 3-2 | Shibe Park (5-2) | 50-49 | Won 3 |
| » Starters: Brooks Lawrence vs Robin Roberts | Fourth | 13½ out |
| » Lost to Phillies (47-51), 6-5 | Shibe Park (5-3) | 50-50 | |
| » Starters: Gerry Staley vs Bob Greenwood | Fourth | 13½ out |
| Sunday, August 1 |
| » Lost to Phillies (48-51), 8-3 | Shibe Park (5-4) | 50-51 | Lost 2 |
| » Starters: Ralph Beard vs Curt Simmons | Fourth | 15 out |
| Tuesday, August 3 |
| » Lost to Dodgers (63-42), 2-1 | Ebbets Field (1-6) | 50-52 | Lost 3 |
| » Starters: Vic Raschi vs Carl Erskine | Fourth | 16 out |
| Wednesday, August 4 |
| » Lost to Dodgers (64-42), 8-7 | Ebbets Field (1-7) | 50-53 | Lost 4 |
| » Starters: Harvey Haddix vs Johnny Podres | Fourth | 17 out |
| Thursday, August 5 |
| » Defeated Dodgers (64-43), 13-4 | Ebbets Field (2-7) | 51-53 | |
| » Starters: Brooks Lawrence vs Preacher Roe | Fourth | 16 out |
| » Major-league debuts: Tommy Lasorda (Dodgers) |
| Friday, August 6 |
| » Lost to Pirates (36-71), 7-3 | Forbes Field (4-1) | 51-54 | |
| » Starters: Gordon Jones vs Dick Littlefield | Fifth | 16½ out |
| » Lost to Pirates (37-71), 6-5 | Forbes Field (4-2) | 51-55 | Lost 2 |
| » Starters: Gerry Staley vs Laurin Pepper | Fifth | 16½ out |
| » Major-league debuts: Gordon Jones (Cardinals) |
| Saturday, August 7 |
| » Defeated Pirates (37-72), 8-6 | Forbes Field (5-2) | 52-55 | |
| » Starters: Royce Lint vs Bob Purkey | Fifth | 15½ out |
| Sunday, August 8 |
| » Lost to Pirates (38-72), 12-4 | Forbes Field (5-3) | 52-56 | |
| » Starters: Harvey Haddix vs Paul LaPalme | Fifth | 16 out |
| » Lost to Pirates (39-72), 5-3 | Forbes Field (5-4) | 52-57 | Lost 2 |
| » Starters: Ralph Beard vs Jake Thies | Fifth | 16 out |
| Tuesday, August 10 |
| » Lost to Braves (61-47), 11-0 | Sportsman's Park III (26-29) | 52-58 | Lost 3 |
| » Starters: Jim Wilson vs Vic Raschi | Fifth | 17 out |
| Wednesday, August 11 |
| » Lost to Braves (62-47), 6-5 | Sportsman's Park III (26-30) | 52-59 | Lost 4 |
| » Starters: Gene Conley vs Brooks Lawrence | Sixth | 17½ out |
| Thursday, August 12 |
| » Lost to Braves (63-47), 3-1 | Sportsman's Park III (26-31) | 52-60 | Lost 5 |
| » Starters: Warren Spahn vs Gordon Jones | Sixth | 18 out |
| Friday, August 13 |
| » Defeated Reds (55-59), 10-8 | Crosley Field (5-3) | 53-60 | |
| » Starters: Harvey Haddix vs Joe Nuxhall | Sixth | 17 out |
| Saturday, August 14 |
| » Lost to Reds (56-59), 6-5 | Crosley Field (5-4) | 53-61 | |
| » Starters: Ralph Beard vs Fred Baczewski | Sixth | 17 out |
| Sunday, August 15 |
| » Defeated Reds (56-60), 14-12 | Crosley Field (6-4) | 54-61 | |
| » Starters: Vic Raschi vs Art Fowler | Sixth | 16 out |
| Tuesday, August 17 |
| » Defeated Braves (66-48), 4-1 | County Stadium (4-2) | 55-61 | Won 2 |
| » Starters: Brooks Lawrence vs Jim Wilson | Fifth | 16 out |
| Wednesday, August 18 |
| » Lost to Braves (67-48), 3-1 | County Stadium (4-3) | 55-62 | |
| » Starters: Harvey Haddix vs Warren Spahn | Sixth | 17 out |
| Thursday, August 19 |
| » Defeated Braves (67-49), 2-1 | County Stadium (5-3) | 56-62 | |
| » Starters: Gordon Jones vs Lew Burdette | Sixth | 17 out |
| Friday, August 20 |
| » Lost to Reds (59-62), 3-2 | Sportsman's Park III (26-32) | 56-63 | |
| » Starters: Joe Nuxhall vs Ralph Beard | Sixth | 18 out |
| Saturday, August 21 |
| » Defeated Reds (59-63), 6-5 | Sportsman's Park III (27-32) | 57-63 | |
| » Starters: Fred Baczewski vs Vic Raschi | Sixth | 17½ out |
| Sunday, August 22 |
| » Defeated Reds (59-64), 9-7 | Sportsman's Park III (28-32) | 58-63 | Won 2 |
| » Starters: Corky Valentine vs Brooks Lawrence | Fifth | 18 out |
| Tuesday, August 24 |
| » Lost to Pirates (45-79), 8-7 | Sportsman's Park III (28-33) | 58-64 | |
| » Starters: Dick Littlefield vs Harvey Haddix | Fifth | 19 out |
| Wednesday, August 25 |
| » Defeated Pirates (45-80), 13-0 | Sportsman's Park III (29-33) | 59-64 | |
| » Starters: Jake Thies vs Gordon Jones | Fourth | 18½ out |
| Thursday, August 26 |
| » Lost to Pirates (46-80), 2-1 | Sportsman's Park III (29-34) | 59-65 | |
| » Starters: Laurin Pepper vs Ralph Beard | Fourth | 19 out |
| Friday, August 27 |
| » Lost to Dodgers (76-49), 8-4 | Sportsman's Park III (29-35) | 59-66 | Lost 2 |
| » Starters: Carl Erskine vs Brooks Lawrence | Fourth | 20 out |
| Saturday, August 28 |
| » Lost to Dodgers (77-49), 7-3 | Sportsman's Park III (29-36) | 59-67 | Lost 3 |
| » Starters: Johnny Podres vs Vic Raschi | Fifth | 20 out |
| Sunday, August 29 |
| » Defeated Giants (79-47), 5-4 | Sportsman's Park III (30-36) | 60-67 | |
| » Starters: Don Liddle vs Harvey Haddix | Fifth | 20 out |
| » Lost to Giants (80-47), 7-4 | Sportsman's Park III (30-37) | 60-68 | |
| » Starters: Al Worthington vs Joe Presko | Fifth | 20 out |
| Monday, August 30 |
| » Lost to Giants (81-47), 4-1 | Sportsman's Park III (30-38) | 60-69 | Lost 2 |
| » Starters: Johnny Antonelli vs Gordon Jones | Fifth | 21 out |
| Tuesday, August 31 |
| » Lost to Giants (82-47), 5-3 | Sportsman's Park III (30-39) | 60-70 | Lost 3 |
| » Starters: Don Liddle vs Ralph Beard | Fifth | 22 out |
| Wednesday, September 1 |
| » Lost to Phillies (60-69), 5-2 | Sportsman's Park III (30-40) | 60-71 | Lost 4 |
| » Starters: Murry Dickson vs Brooks Lawrence | Sixth | 22 out |
| Thursday, September 2 |
| » Lost to Phillies (61-69), 5-4 | Sportsman's Park III (30-41) | 60-72 | Lost 5 |
| » Starters: Robin Roberts vs Harvey Haddix | Sixth | 22½ out |
| Friday, September 3 |
| » Lost to Cubs (57-77), 4-3 | Sportsman's Park III (30-42) | 60-73 | Lost 6 |
| » Starters: Paul Minner vs Gordon Jones | Sixth | 23½ out |
| Saturday, September 4 |
| » Lost to Cubs (58-77), 6-5 | Sportsman's Park III (30-43) | 60-74 | Lost 7 |
| » Starters: Bob Rush vs Vic Raschi | Sixth | 24½ out |
| Sunday, September 5 |
| » Defeated Cubs (58-78), 6-2 | Sportsman's Park III (31-43) | 61-74 | |
| » Starters: Howie Pollet vs Brooks Lawrence | Sixth | 23½ out |
| Monday, September 6 |
| » Defeated Reds (65-72), 8-1 | Crosley Field (7-4) | 62-74 | Won 2 |
| » Starters: Harvey Haddix vs Joe Nuxhall | Sixth | 23 out |
| Wednesday, September 8 |
| » Defeated Dodgers (81-57), 6-5 | Ebbets Field (3-7) | 63-74 | Won 3 |
| » Starters: Gordon Jones vs Carl Erskine | Sixth | 23 out |
| Thursday, September 9 |
| » Lost to Dodgers (82-57), 10-1 | Ebbets Field (3-8) | 63-75 | |
| » Starters: Vic Raschi vs Johnny Podres | Sixth | 23½ out |
| Friday, September 10 |
| » Lost to Pirates (49-91), 3-2 | Forbes Field (5-5) | 63-76 | Lost 2 |
| » Starters: Brooks Lawrence vs Max Surkont | Sixth | 23½ out |
| Saturday, September 11 |
| » Defeated Pirates (49-92), 7-2 | Forbes Field (6-5) | 64-76 | |
| » Starters: Tom Poholsky vs Laurin Pepper | Sixth | 23½ out |
| Sunday, September 12 |
| » Defeated Giants (88-53), 4-3 | Polo Grounds V (6-4) | 65-76 | Won 2 |
| » Starters: Harvey Haddix vs Windy McCall | Sixth | 22½ out |
| Monday, September 13 |
| » Lost to Giants (89-53), 1-0 | Polo Grounds V (6-5) | 65-77 | |
| » Starters: Gordon Jones vs Johnny Antonelli | Sixth | 23½ out |
| Tuesday, September 14 |
| » Defeated Phillies (68-75), 5-2 | Shibe Park (6-4) | 66-77 | |
| » Starters: Brooks Lawrence vs Ron Mrozinski | Sixth | 23½ out |
| Wednesday, September 15 |
| » Defeated Phillies (68-76), 3-1 | Shibe Park (7-4) | 67-77 | Won 2 |
| » Starters: Tom Poholsky vs Herm Wehmeier | Sixth | 23 out |
| Friday, September 17 |
| » Lost to Braves (85-60), 6-4 | Sportsman's Park III (31-44) | 67-78 | |
| » Starters: Chet Nichols vs Harvey Haddix | Sixth | 24 out |
| Saturday, September 18 |
| » Defeated Braves (85-61), 3-0 | Sportsman's Park III (32-44) | 68-78 | |
| » Starters: Jim Wilson vs Gordon Jones | Sixth | 24 out |
| Sunday, September 19 |
| » Defeated Braves (85-62), 7-6 | Sportsman's Park III (33-44) | 69-78 | Won 2 |
| » Starters: Bob Buhl vs Brooks Lawrence | Fifth | 23½ out |
| Monday, September 20 |
| » Defeated Cubs (60-89), 7-2 | Wrigley Field (3-5) | 70-78 | Won 3 |
| » Starters: Tom Poholsky vs Paul Minner | Fifth | 23½ out |
| Tuesday, September 21 |
| » Lost to Cubs (61-89), 4-3 | Wrigley Field (3-6) | 70-79 | |
| » Starters: Vic Raschi vs Bob Rush | Sixth | 25 out |
| » Lost to Cubs (62-89), 3-2 | Wrigley Field (3-7) | 70-80 | Lost 2 |
| » Starters: Harvey Haddix vs Johnny Klippstein | Sixth | 25 out |
| Wednesday, September 22 |
| » Defeated Cubs (62-90), 6-3 | Wrigley Field (4-7) | 71-80 | |
| » Starters: Brooks Lawrence vs Dave Cole | Sixth | 24 out |
| Friday, September 24 |
| » Lost to Braves (88-64), 4-2 | County Stadium (5-4) | 71-81 | |
| » Starters: Gordon Jones vs Warren Spahn | Sixth | 24½ out |
| Saturday, September 25 |
| » Lost to Braves (89-64), 3-0 | County Stadium (5-5) | 71-82 | Lost 2 |
| » Starters: Tom Poholsky vs Lew Burdette | Sixth | 24½ out |
| Sunday, September 26 |
| » |
