| Saturday, January 3 |
| Former Indian Chuck Workman dies in Kansas City, MO at the age of 38. |
| Saturday, January 24 |
| Future Indian Tim Stoddard is born in East Chicago, IN. |
| Wednesday, February 11 |
| Future Indian Tom Veryzer is born in Port Jefferson, NY. |
| Tuesday, February 17 |
| Future Indian Jamie Easterly is born in Houston, TX. |
| Friday, February 27 |
| Future Indian Ron Hassey is born in Tucson, AZ. |
| Monday, March 23 |
| Future Indian Bo Diaz is born in Cua, Venezuela. |
| Friday, March 27 |
| Future Indian Gary Alexander is born in Los Angeles, CA. |
| Monday, April 13 |
| » Major-league debuts: Bill Bruton (Braves) |
| Tuesday, April 14 |
| » Defeated White Sox (0-1), 6-0 | Cleveland Stadium (1-0) | 1-0 | |
| » Starters: Saul Rogovin vs Bob Lemon | First | -- |
| Thursday, April 16 |
| » Defeated Tigers (0-2), 11-8 | Tiger Stadium (1-0) | 2-0 | Won 2 |
| » Starters: Mike Garcia vs Art Houtteman | First | -- |
| Friday, April 17 |
| » Lost to Tigers (1-2), 6-5 | Tiger Stadium (1-1) | 2-1 | |
| » Starters: Bob Feller vs Bill Wight | Second | ½ out |
| Saturday, April 18 |
| » Lost to White Sox (2-2), 7-6 | Comiskey Park I (0-1) | 2-2 | Lost 2 |
| » Starters: Early Wynn vs Tommy Byrne | Fourth | 1½ out |
| » Major-league debuts: Dave Hoskins (Indians) |
| Former Indian Harry Niles dies in Sturgis, MI at the age of 73. |
| Tuesday, April 21 |
| » Defeated Browns (5-2), 4-3 | Cleveland Stadium (2-0) | 3-2 | |
| » Starters: Harry Brecheen vs Bob Lemon | Second | 1 out |
| » Major-league debuts: Mike Blyzka (Browns) |
| Wednesday, April 22 |
| » Major-league debuts: Carlos Bernier (Pirates) |
| Friday, April 24 |
| » Defeated Tigers (2-8), 4-1 | Cleveland Stadium (3-0) | 4-2 | Won 2 |
| » Starters: Art Houtteman vs Mike Garcia | Second | 2 out |
| Saturday, April 25 |
| » Defeated Tigers (2-9), 4-3 | Cleveland Stadium (4-0) | 5-2 | Won 3 |
| » Starters: Hal Newhouser vs Early Wynn | Second | 2 out |
| Sunday, April 26 |
| » Defeated Tigers (2-10), 2-1 | Cleveland Stadium (5-0) | 6-2 | Won 4 |
| » Starters: Ted Gray vs Bob Feller | First | -- |
| » Defeated Tigers (2-11), 12-2 | Cleveland Stadium (6-0) | 7-2 | Won 5 |
| » Starters: Ned Garver vs Bob Lemon | First | -- |
| Tuesday, April 28 |
| » Lost to Athletics (7-5), 3-2 | Cleveland Stadium (6-1) | 7-3 | |
| » Starters: Bobby Shantz vs Mike Garcia | Second | 1½ out |
| Wednesday, April 29 |
| » Defeated Athletics (7-6), 2-1 | Cleveland Stadium (7-1) | 8-3 | |
| » Starters: Alex Kellner vs Early Wynn | Second | 1 out |
| Friday, May 1 |
| » Lost to Red Sox (7-6), 8-1 | Cleveland Stadium (7-2) | 8-4 | |
| » Starters: Marv Grissom vs Bob Lemon | Second | 1½ out |
| Saturday, May 2 |
| » Lost to Red Sox (8-6), 5-1 | Cleveland Stadium (7-3) | 8-5 | Lost 2 |
| » Starters: Hal Brown vs Bob Feller | Third | 1½ out |
| Sunday, May 3 |
| » Defeated Senators (6-11), 7-0 | Cleveland Stadium (8-3) | 9-5 | |
| » Starters: Connie Marrero vs Early Wynn | Second | 1 out |
| » Defeated Senators (6-12), 4-3 | Cleveland Stadium (9-3) | 10-5 | Won 2 |
| » Starters: Walt Masterson vs Mike Garcia | Second | 1 out |
| Tuesday, May 5 |
| » Lost to Yankees (13-6), 11-1 | Cleveland Stadium (9-4) | 10-6 | |
| » Starters: Whitey Ford vs Bob Lemon | Second | 1½ out |
| Wednesday, May 6 |
| Future Indian Larry Andersen is born in Portland, OR. |
| Friday, May 8 |
| » Defeated Browns (10-10), 7-4 | Sportsman's Park III (1-0) | 11-6 | |
| » Starters: Early Wynn vs Don Larsen | Second | 1½ out |
| Saturday, May 9 |
| » Defeated Browns (10-11), 3-2 | Sportsman's Park III (2-0) | 12-6 | Won 2 |
| » Starters: Mike Garcia vs Dick Littlefield | Second | 1½ out |
| Sunday, May 10 |
| » Defeated Browns (10-12), 12-3 | Sportsman's Park III (3-0) | 13-6 | Won 3 |
| » Starters: Bob Feller vs Virgil Trucks | First | -- |
| Monday, May 11 |
| » Lost to White Sox (15-10), 2-1 | Cleveland Stadium (9-5) | 13-7 | |
| » Starters: Billy Pierce vs Bob Lemon | Second | 1 out |
| Tuesday, May 12 |
| » Lost to Yankees (16-7), 7-0 | Yankee Stadium (0-1) | 13-8 | Lost 2 |
| » Starters: Early Wynn vs Whitey Ford | Second | 2 out |
| Wednesday, May 13 |
| » Lost to Yankees (17-7), 9-4 | Yankee Stadium (0-2) | 13-9 | Lost 3 |
| » Starters: Mike Garcia vs Eddie Lopat | Third | 3 out |
| Thursday, May 14 |
| » Lost to Red Sox (13-11), 5-4 | Fenway Park (0-1) | 13-10 | Lost 4 |
| » Starters: Bob Feller vs Hal Brown | Third | 3 out |
| Saturday, May 16 |
| » Lost to Red Sox (14-11), 1-0 | Fenway Park (0-2) | 13-11 | Lost 5 |
| » Starters: Bob Lemon vs Mickey McDermott | Fourth | 3 out |
| Sunday, May 17 |
| » Defeated Athletics (12-17), 7-3 | Shibe Park (1-0) | 14-11 | |
| » Starters: Early Wynn vs Bobby Shantz | Third | 2½ out |
| » Defeated Athletics (12-18), 9-1 | Shibe Park (2-0) | 15-11 | Won 2 |
| » Starters: Mike Garcia vs Alex Kellner | Third | 2½ out |
| Wednesday, May 20 |
| » Lost to Senators (16-15), 8-3 | Griffith Stadium (0-1) | 15-12 | |
| » Starters: Bob Feller vs Spec Shea | Fourth | 4 out |
| Saturday, May 23 |
| » Defeated Browns (12-19), 5-1 | Cleveland Stadium (10-5) | 16-12 | |
| » Starters: Dick Littlefield vs Bob Lemon | Fourth | 4 out |
| Sunday, May 24 |
| » Defeated Browns (12-20), 5-1 | Cleveland Stadium (11-5) | 17-12 | Won 2 |
| » Starters: Bobo Holloman vs Early Wynn | Second | 3½ out |
| » Defeated Browns (12-21), 9-8 | Cleveland Stadium (12-5) | 18-12 | Won 3 |
| » Starters: Bob Cain vs Mike Garcia | Second | 3½ out |
| Tuesday, May 26 |
| » Defeated Tigers (10-27), 9-8 | Cleveland Stadium (13-5) | 19-12 | Won 4 |
| » Starters: Bill Wight vs Bob Feller | Second | 2½ out |
| Wednesday, May 27 |
| » Lost to Browns (13-23), 5-1 | Sportsman's Park III (3-1) | 19-13 | |
| » Starters: Bob Lemon vs Bobo Holloman | Third | 3½ out |
| Thursday, May 28 |
| » Lost to Browns (14-23), 7-5 | Sportsman's Park III (3-2) | 19-14 | Lost 2 |
| » Starters: Dave Hoskins vs Dick Littlefield | Third | 4½ out |
| Friday, May 29 |
| » Defeated White Sox (23-16), 2-1 | Comiskey Park I (1-1) | 20-14 | |
| » Starters: Mike Garcia vs Bob Keegan | Third | 4½ out |
| Saturday, May 30 |
| » Defeated White Sox (23-17), 7-2 | Comiskey Park I (2-1) | 21-14 | Won 2 |
| » Starters: Bob Feller vs Billy Pierce | Third | 4½ out |
| » Lost to White Sox (24-17), 6-5 | Comiskey Park I (2-2) | 21-15 | |
| » Starters: Early Wynn vs Lou Kretlow | Third | 4½ out |
| Sunday, May 31 |
| » Defeated Tigers (10-31), 8-1 | Tiger Stadium (2-1) | 22-15 | |
| » Starters: Bob Lemon vs Art Houtteman | Second | 4½ out |
| Tuesday, June 2 |
| » Defeated Red Sox (21-22), 7-3 | Cleveland Stadium (14-5) | 23-15 | Won 2 |
| » Starters: Marv Grissom vs Mike Garcia | Second | 4½ out |
| Wednesday, June 3 |
| » Lost to Red Sox (22-22), 4-3 | Cleveland Stadium (14-6) | 23-16 | |
| » Starters: Sid Hudson vs Early Wynn | Second | 5½ out |
| Future Indian Ed Glynn is born in Flushing, NY. |
| Thursday, June 4 |
| » Defeated Red Sox (22-23), 8-1 | Cleveland Stadium (15-6) | 24-16 | |
| » Starters: Mel Parnell vs Bob Lemon | Second | 5½ out |
| Friday, June 5 |
| » Defeated Athletics (21-25), 3-2 | Cleveland Stadium (16-6) | 25-16 | Won 2 |
| » Starters: Alex Kellner vs Bob Chakales | Second | 5½ out |
| Saturday, June 6 |
| » Defeated Athletics (21-26), 2-0 | Cleveland Stadium (17-6) | 26-16 | Won 3 |
| » Starters: Harry Byrd vs Mike Garcia | Second | 5½ out |
| Sunday, June 7 |
| » Defeated Athletics (21-27), 8-4 | Cleveland Stadium (18-6) | 27-16 | Won 4 |
| » Starters: Morrie Martin vs Bob Feller | Second | 5½ out |
| » Defeated Athletics (21-28), 4-3 | Cleveland Stadium (19-6) | 28-16 | Won 5 |
| » Starters: Charlie Bishop vs Early Wynn | Second | 5½ out |
| Tuesday, June 9 |
| » Defeated Senators (27-23), 2-1 | Cleveland Stadium (20-6) | 29-16 | Won 6 |
| » Starters: Johnny Schmitz vs Bob Lemon | Second | 5½ out |
| Wednesday, June 10 |
| » Defeated Senators (27-24), 2-1 | Cleveland Stadium (21-6) | 30-16 | Won 7 |
| » Starters: Sonny Dixon vs Mike Garcia | Second | 5½ out |
| Thursday, June 11 |
| » Lost to Senators (28-24), 2-1 | Cleveland Stadium (21-7) | 30-17 | |
| » Starters: Walt Masterson vs Steve Gromek | Second | 6½ out |
| Friday, June 12 |
| » Lost to Yankees (38-11), 4-2 | Cleveland Stadium (21-8) | 30-18 | Lost 2 |
| » Starters: Whitey Ford vs Early Wynn | Second | 7½ out |
| Saturday, June 13 |
| » Lost to Yankees (39-11), 9-4 | Cleveland Stadium (21-9) | 30-19 | Lost 3 |
| » Starters: Eddie Lopat vs Bob Feller | Second | 8½ out |
| Sunday, June 14 |
| » Lost to Yankees (40-11), 6-2 | Cleveland Stadium (21-10) | 30-20 | Lost 4 |
| » Starters: Johnny Sain vs Bob Lemon | Second | 10½ out |
| » Lost to Yankees (41-11), 3-0 | Cleveland Stadium (21-11) | 30-21 | Lost 5 |
| » Starters: Vic Raschi vs Mike Garcia | Second | 10½ out |
| Future Indian Luis Aponte is born in ElTigre, Venezuela. |
| Tuesday, June 16 |
| » Lost to Athletics (28-29), 9-7 | Shibe Park (2-1) | 30-22 | Lost 6 |
| » Starters: Early Wynn vs Charlie Bishop | Second | 10½ out |
| Wednesday, June 17 |
| » Defeated Athletics (28-30), 9-6 | Shibe Park (3-1) | 31-22 | |
| » Starters: Bob Feller vs Harry Byrd | Second | 10½ out |
| Thursday, June 18 |
| » Defeated Athletics (28-31), 6-4 | Shibe Park (4-1) | 32-22 | Won 2 |
| » Starters: Bob Lemon vs Carl Scheib | Second | 11 out |
| Friday, June 19 |
| » Defeated Senators (30-29), 4-2 | Griffith Stadium (1-1) | 33-22 | Won 3 |
| » Starters: Mike Garcia vs Tommy Byrne | Second | 10 out |
| Saturday, June 20 |
| » Lost to Senators (31-29), 7-3 | Griffith Stadium (1-2) | 33-23 | |
| » Starters: Early Wynn vs Bob Porterfield | Second | 11 out |
| Sunday, June 21 |
| » Lost to Senators (32-29), 5-1 | Griffith Stadium (1-3) | 33-24 | Lost 2 |
| » Starters: Art Houtteman vs Spec Shea | Second | 11½ out |
| Monday, June 22 |
| » Defeated Senators (32-30), 5-2 | Griffith Stadium (2-3) | 34-24 | |
| » Starters: Bob Feller vs Johnny Schmitz | Second | 10½ out |
| » Defeated Senators (32-31), 5-2 | Griffith Stadium (3-3) | 35-24 | Won 2 |
| » Starters: Bob Lemon vs Walt Masterson | Second | 10½ out |
| Tuesday, June 23 |
| » Lost to Red Sox (36-29), 6-4 | Fenway Park (0-3) | 35-25 | |
| » Starters: Mike Garcia vs Willard Nixon | Second | 11 out |
| » Lost to Red Sox (37-29), 2-1 | Fenway Park (0-4) | 35-26 | Lost 2 |
| » Starters: Bob Chakales vs Mickey McDermott | Second | 11 out |
| Wednesday, June 24 |
| » Defeated Red Sox (37-30), 13-9 | Fenway Park (1-4) | 36-26 | |
| » Starters: Early Wynn vs Marv Grissom | Second | 10 out |
| Thursday, June 25 |
| » Defeated Red Sox (37-31), 15-4 | Fenway Park (2-4) | 37-26 | Won 2 |
| » Starters: Art Houtteman vs Mel Parnell | Second | 9 out |
| Friday, June 26 |
| » Defeated Yankees (46-18), 7-2 | Yankee Stadium (1-2) | 38-26 | Won 3 |
| » Starters: Bob Lemon vs Vic Raschi | Second | 8 out |
| Saturday, June 27 |
| » Defeated Yankees (46-19), 5-0 | Yankee Stadium (2-2) | 39-26 | Won 4 |
| » Starters: Mike Garcia vs Eddie Lopat | Second | 7 out |
| Sunday, June 28 |
| » Defeated Yankees (46-20), 4-1 | Yankee Stadium (3-2) | 40-26 | Won 5 |
| » Starters: Early Wynn vs Whitey Ford | Second | 6 out |
| Tuesday, June 30 |
| » Defeated Tigers (20-49), 6-4 | Tiger Stadium (3-1) | 41-26 | Won 6 |
| » Starters: Art Houtteman vs Ned Garver | Second | 5 out |
| Wednesday, July 1 |
| » Lost to Tigers (21-49), 4-2 | Tiger Stadium (3-2) | 41-27 | |
| » Starters: Bob Lemon vs Ted Gray | Second | 5 out |
| Thursday, July 2 |
| » Lost to Tigers (22-49), 4-2 | Tiger Stadium (3-3) | 41-28 | Lost 2 |
| » Starters: Mike Garcia vs Steve Gromek | Second | 6 out |
| Friday, July 3 |
| » Defeated Tigers (22-50), 8-1 | Cleveland Stadium (22-11) | 42-28 | |
| » Starters: Billy Hoeft vs Early Wynn | Second | 6 out |
| Saturday, July 4 |
| » Defeated Tigers (22-51), 4-1 | Cleveland Stadium (23-11) | 43-28 | Won 2 |
| » Starters: Ned Garver vs Bob Feller | Third | 7 out |
| » Lost to Tigers (23-51), 6-1 | Cleveland Stadium (23-12) | 43-29 | |
| » Starters: Dick Marlowe vs Art Houtteman | Third | 7 out |
| Sunday, July 5 |
| » Defeated White Sox (44-30), 7-6 | Cleveland Stadium (24-12) | 44-29 | |
| » Starters: Sandy Consuegra vs Bob Lemon | Third | 6 out |
| » Lost to White Sox (45-30), 4-0 | Cleveland Stadium (24-13) | 44-30 | |
| » Starters: Billy Pierce vs Bob Chakales | Third | 6 out |
| Monday, July 6 |
| » Defeated White Sox (45-31), 6-3 | Cleveland Stadium (25-13) | 45-30 | |
| » Starters: Saul Rogovin vs Mike Garcia | Second | 6½ out |
| Tuesday, July 7 |
| » Defeated Browns (27-53), 6-3 | Sportsman's Park III (4-2) | 46-30 | Won 2 |
| » Starters: Early Wynn vs Dick Littlefield | Second | 5½ out |
| Wednesday, July 8 |
| » Lost to Browns (28-53), 6-3 | Sportsman's Park III (4-3) | 46-31 | |
| » Starters: Art Houtteman vs Lou Kretlow | Third | 6½ out |
| Thursday, July 9 |
| » Defeated Browns (28-54), 9-1 | Sportsman's Park III (5-3) | 47-31 | |
| » Starters: Bob Lemon vs Don Larsen | Third | 5½ out |
| Friday, July 10 |
| » Defeated White Sox (48-32), 3-0 | Comiskey Park I (3-2) | 48-31 | Won 2 |
| » Starters: Bob Feller vs Billy Pierce | Third | 6 out |
| » Lost to White Sox (49-32), 16-5 | Comiskey Park I (3-3) | 48-32 | |
| » Starters: Mike Garcia vs Gene Bearden | Third | 6 out |
| » Major-league debuts: Al Smith (Indians) |
| Saturday, July 11 |
| » Lost to White Sox (50-32), 5-4 | Comiskey Park I (3-4) | 48-33 | Lost 2 |
| » Starters: Early Wynn vs Joe Dobson | Third | 7 out |
| Sunday, July 12 |
| » Lost to White Sox (51-32), 14-2 | Comiskey Park I (3-5) | 48-34 | Lost 3 |
| » Starters: Art Houtteman vs Mike Fornieles | Third | 8½ out |
| » Lost to White Sox (52-32), 3-1 | Comiskey Park I (3-6) | 48-35 | Lost 4 |
| » Starters: Bob Lemon vs Virgil Trucks | Third | 8½ out |
| Thursday, July 16 |
| » Defeated Athletics (34-52), 5-3 | Cleveland Stadium (26-13) | 49-35 | |
| » Starters: Marion Fricano vs Mike Garcia | Third | 8 out |
| Friday, July 17 |
| » Defeated Athletics (34-53), 5-0 | Cleveland Stadium (27-13) | 50-35 | Won 2 |
| » Starters: Bobby Shantz vs Bob Lemon | Third | 8 out |
| Saturday, July 18 |
| » Lost to Athletics (35-53), 9-3 | Cleveland Stadium (27-14) | 50-36 | |
| » Starters: Harry Byrd vs Bob Feller | Third | 9 out |
| Sunday, July 19 |
| » Lost to Red Sox (51-39), 2-0 | Cleveland Stadium (27-15) | 50-37 | Lost 2 |
| » Starters: Mickey McDermott vs Early Wynn | Fourth | 11 out |
| » Lost to Red Sox (52-39), 7-5 | Cleveland Stadium (27-16) | 50-38 | Lost 3 |
| » Starters: Bill Henry vs Art Houtteman | Fourth | 11 out |
| Tuesday, July 21 |
| » Defeated Yankees (61-28), 8-3 | Cleveland Stadium (28-16) | 51-38 | |
| » Starters: Johnny Sain vs Bob Lemon | Third | 10 out |
| Wednesday, July 22 |
| » Defeated Yankees (61-29), 6-4 | Cleveland Stadium (29-16) | 52-38 | Won 2 |
| » Starters: Whitey Ford vs Mike Garcia | Third | 9 out |
| Thursday, July 23 |
| » Defeated Yankees (61-30), 10-2 | Cleveland Stadium (30-16) | 53-38 | Won 3 |
| » Starters: Tom Gorman vs Early Wynn | Third | 8 out |
| Friday, July 24 |
| » Lost to Senators (44-50), 6-4 | Cleveland Stadium (30-17) | 53-39 | |
| » Starters: Chuck Stobbs vs Art Houtteman | Fourth | 8 out |
| Saturday, July 25 |
| » Defeated Senators (44-51), 6-4 | Cleveland Stadium (31-17) | 54-39 | |
| » Starters: Johnny Schmitz vs Bob Lemon | Fourth | 8 out |
| Sunday, July 26 |
| » Lost to Senators (45-51), 4-3 | Cleveland Stadium (31-18) | 54-40 | |
| » Starters: Bob Porterfield vs Bob Feller | Fourth | 8 out |
| » Defeated Senators (45-52), 7-6 | Cleveland Stadium (32-18) | 55-40 | |
| » Starters: Al Sima vs Mike Garcia | Fourth | 8 out |
| Tuesday, July 28 |
| » Lost to Yankees (64-32), 4-2 | Yankee Stadium (3-3) | 55-41 | |
| » Starters: Early Wynn vs Whitey Ford | Fourth | 9 out |
| Wednesday, July 29 |
| » Lost to Yankees (65-32), 7-3 | Yankee Stadium (3-4) | 55-42 | Lost 2 |
| » Starters: Bob Lemon vs Vic Raschi | Fourth | 10 out |
| Thursday, July 30 |
| » Defeated Yankees (65-33), 4-3 | Yankee Stadium (4-4) | 56-42 | |
| » Starters: Mike Garcia vs Eddie Lopat | Third | 9 out |
| Friday, July 31 |
| » Defeated Athletics (43-56), 12-6 | Shibe Park (5-1) | 57-42 | Won 2 |
| » Starters: Art Houtteman vs Harry Byrd | Third | 9 out |
| Saturday, August 1 |
| » Defeated Athletics (43-57), 5-2 | Shibe Park (6-1) | 58-42 | Won 3 |
| » Starters: Bob Feller vs Charlie Bishop | Third | 8 out |
| Sunday, August 2 |
| » Defeated Athletics (43-58), 10-1 | Shibe Park (7-1) | 59-42 | Won 4 |
| » Starters: Bob Lemon vs Bobby Shantz | Third | 7 out |
| » Defeated Athletics (43-59), 7-1 | Shibe Park (8-1) | 60-42 | Won 5 |
| » Starters: Early Wynn vs Alex Kellner | Third | 7 out |
| Tuesday, August 4 |
| » Defeated Senators (49-56), 3-0 | Griffith Stadium (4-3) | 61-42 | Won 6 |
| » Starters: Mike Garcia vs Chuck Stobbs | Third | 7½ out |
| Wednesday, August 5 |
| » Lost to Senators (50-56), 11-0 | Griffith Stadium (4-4) | 61-43 | |
| » Starters: Dave Hoskins vs Bob Porterfield | Third | 8½ out |
| Thursday, August 6 |
| » Lost to Senators (51-56), 4-1 | Griffith Stadium (4-5) | 61-44 | Lost 2 |
| » Starters: Bob Feller vs Spec Shea | Third | 9½ out |
| Friday, August 7 |
| » Lost to Red Sox (60-49), 4-2 | Fenway Park (2-5) | 61-45 | Lost 3 |
| » Starters: Bob Lemon vs Mel Parnell | Third | 10½ out |
| Saturday, August 8 |
| » Lost to Red Sox (61-49), 5-4 | Fenway Park (2-6) | 61-46 | Lost 4 |
| » Starters: Early Wynn vs Bill Henry | Third | 12 out |
| Sunday, August 9 |
| » Defeated Red Sox (61-50), 9-3 | Fenway Park (3-6) | 62-46 | |
| » Starters: Mike Garcia vs Mickey McDermott | Third | 11 out |
| Former Indian Joe Evans dies in Gulfport, MS at the age of 59. |
| Tuesday, August 11 |
| » Lost to White Sox (68-43), 6-2 | Cleveland Stadium (32-19) | 62-47 | |
| » Starters: Connie Johnson vs Bob Lemon | Third | 11 out |
| Wednesday, August 12 |
| » Defeated White Sox (68-44), 7-4 | Cleveland Stadium (33-19) | 63-47 | |
| » Starters: Mike Fornieles vs Early Wynn | Third | 11 out |
| Thursday, August 13 |
| » Lost to White Sox (69-44), 7-3 | Cleveland Stadium (33-20) | 63-48 | |
| » Starters: Virgil Trucks vs Mike Garcia | Third | 12 out |
| Friday, August 14 |
| » Defeated Browns (39-77), 8-7 | Sportsman's Park III (6-3) | 64-48 | |
| » Starters: Bob Feller vs Duane Pillette | Third | 11½ out |
| Sunday, August 16 |
| » Lost to Browns (40-77), 7-6 | Sportsman's Park III (6-4) | 64-49 | |
| » Starters: Early Wynn vs Dick Littlefield | Third | 13 out |
| » Lost to Browns (41-77), 7-5 | Sportsman's Park III (6-5) | 64-50 | Lost 2 |
| » Starters: Bob Lemon vs Don Larsen | Third | 13 out |
| Tuesday, August 18 |
| » Lost to Tigers (43-73), 3-2 | Tiger Stadium (3-4) | 64-51 | Lost 3 |
| » Starters: Mike Garcia vs Steve Gromek | Third | 14 out |
| Wednesday, August 19 |
| » Lost to Tigers (44-73), 4-2 | Tiger Stadium (3-5) | 64-52 | Lost 4 |
| » Starters: Early Wynn vs Billy Hoeft | Third | 15 out |
| Thursday, August 20 |
| » Defeated Tigers (44-74), 13-7 | Tiger Stadium (4-5) | 65-52 | |
| » Starters: Bob Lemon vs Ted Gray | Third | 15 out |
| Friday, August 21 |
| » Defeated Browns (42-80), 7-3 | Cleveland Stadium (34-20) | 66-52 | Won 2 |
| » Starters: Dick Littlefield vs Bob Feller | Third | 14½ out |
| » Defeated Browns (42-81), 3-2 | Cleveland Stadium (35-20) | 67-52 | Won 3 |
| » Starters: Harry Brecheen vs Dave Hoskins | Third | 14½ out |
| Saturday, August 22 |
| » Defeated Browns (42-82), 4-1 | Cleveland Stadium (36-20) | 68-52 | Won 4 |
| » Starters: Lou Kretlow vs Mike Garcia | Third | 13½ out |
| Sunday, August 23 |
| » Defeated Browns (42-83), 3-1 | Cleveland Stadium (37-20) | 69-52 | Won 5 |
| » Starters: Duane Pillette vs Early Wynn | Third | 13 out |
| » Defeated Browns (42-84), 9-0 | Cleveland Stadium (38-20) | 70-52 | Won 6 |
| » Starters: Bob Turley vs Art Houtteman | Third | 13 out |
| Tuesday, August 25 |
| » Lost to Senators (61-65), 8-4 | Cleveland Stadium (38-21) | 70-53 | |
| » Starters: Bob Porterfield vs Bob Lemon | Third | 14 out |
| Future Indian Bob Lacey is born in Fredericksburg, VA. |
| Wednesday, August 26 |
| » Defeated Senators (61-66), 9-5 | Cleveland Stadium (39-21) | 71-53 | |
| » Starters: Chuck Stobbs vs Dave Hoskins | Third | 14 out |
| Thursday, August 27 |
| » Defeated Yankees (85-40), 4-2 | Cleveland Stadium (40-21) | 72-53 | Won 2 |
| » Starters: Whitey Ford vs Mike Garcia | Third | 13 out |
| Friday, August 28 |
| » Defeated Yankees (85-41), 3-2 | Cleveland Stadium (41-21) | 73-53 | Won 3 |
| » Starters: Eddie Lopat vs Early Wynn | Third | 12 out |
| Saturday, August 29 |
| » Defeated Yankees (85-42), 6-0 | Cleveland Stadium (42-21) | 74-53 | Won 4 |
| » Starters: Steve Kraly vs Bob Lemon | Third | 11 out |
| Sunday, August 30 |
| » Defeated Red Sox (71-59), 6-5 | Cleveland Stadium (43-21) | 75-53 | Won 5 |
| » Starters: Hal Brown vs Bob Feller | Third | 10 out |
| » Defeated Red Sox (71-60), 8-4 | Cleveland Stadium (44-21) | 76-53 | Won 6 |
| » Starters: Ben Flowers vs Art Houtteman | Third | 10 out |
| Monday, August 31 |
| » Lost to Red Sox (72-60), 6-4 | Cleveland Stadium (44-22) | 76-54 | |
| » Starters: Mickey McDermott vs Mike Garcia | Third | 10½ out |
| Future Indian Bill Nahorodny is born in Hamtramck, MI. |
| Tuesday, September 1 |
| » Defeated Red Sox (72-61), 13-3 | Cleveland Stadium (45-22) | 77-54 | |
| » Starters: Willard Nixon vs Early Wynn | Third | 10½ out |
| Wednesday, September 2 |
| » Defeated Athletics (52-81), 6-3 | Cleveland Stadium (46-22) | 78-54 | Won 2 |
| » Starters: Harry Byrd vs Bob Lemon | Third | 10½ out |
| Thursday, September 3 |
| » Defeated Athletics (52-82), 9-4 | Cleveland Stadium (47-22) | 79-54 | Won 3 |
| » Starters: Carl Scheib vs Dave Hoskins | Second | 10½ out |
| Future Indian Mike Paxton is born in Memphis, TN. |
| Friday, September 4 |
| » Tied White Sox, 6-6 | Cleveland Stadium (47-22) | 79-54 | |
| » Starters: Billy Pierce vs Mike Garcia | Second | 10½ out |
| Saturday, September 5 |
| » Lost to White Sox (80-54), 2-0 | Cleveland Stadium (47-23) | 79-55 | |
| » Starters: Saul Rogovin vs Early Wynn | Second | 10½ out |
| » Defeated White Sox (80-55), 4-1 | Cleveland Stadium (48-23) | 80-55 | |
| » Starters: Sandy Consuegra vs Bob Feller | Second | 10½ out |
| Sunday, September 6 |
| » Defeated White Sox (80-56), 4-2 | Cleveland Stadium (49-23) | 81-55 | Won 2 |
| » Starters: Virgil Trucks vs Art Houtteman | Second | 10 out |
| Monday, September 7 |
| » Defeated Browns (48-90), 3-0 | Cleveland Stadium (50-23) | 82-55 | Won 3 |
| » Starters: Harry Brecheen vs Bob Lemon | Second | 9 out |
| » Defeated Browns (48-91), 10-7 | Cleveland Stadium (51-23) | 83-55 | Won 4 |
| » Starters: Satchel Paige vs Dave Hoskins | Second | 9 out |
| Wednesday, September 9 |
| » Defeated Red Sox (76-64), 2-1 | Fenway Park (4-6) | 84-55 | Won 5 |
| » Starters: Mike Garcia vs Bill Henry | Second | 9 out |
| Thursday, September 10 |
| » Lost to Red Sox (77-64), 14-4 | Fenway Park (4-7) | 84-56 | |
| » Starters: Early Wynn vs Mickey McDermott | Second | 10 out |
| Friday, September 11 |
| » Lost to Senators (71-69), 6-4 | Griffith Stadium (4-6) | 84-57 | Lost 2 |
| » Starters: Bob Lemon vs Spec Shea | Second | 10 out |
| Saturday, September 12 |
| » Lost to Senators (72-69), 4-3 | Griffith Stadium (4-7) | 84-58 | Lost 3 |
| » Starters: Art Houtteman vs Bob Porterfield | Second | 11 out |
| Sunday, September 13 |
| » Lost to Yankees (94-45), 6-3 | Yankee Stadium (4-5) | 84-59 | Lost 4 |
| » Starters: Mike Garcia vs Vic Raschi | Second | 12 out |
| Monday, September 14 |
| » Lost to Yankees (95-45), 8-5 | Yankee Stadium (4-6) | 84-60 | Lost 5 |
| » Starters: Early Wynn vs Whitey Ford | Second | 13 out |
| Tuesday, September 15 |
| » Defeated Yankees (95-46), 1-0 | Yankee Stadium (5-6) | 85-60 | |
| » Starters: Bob Lemon vs Steve Kraly | Second | 12 out |
| Wednesday, September 16 |
| » Defeated Athletics (54-91), 7-2 | Shibe Park (9-1) | 86-60 | Won 2 |
| » Starters: Bob Feller vs Marion Fricano | Second | 11½ out |
| Thursday, September 17 |
| » Defeated Athletics (54-92), 5-4 | Shibe Park (10-1) | 87-60 | Won 3 |
| » Starters: Mike Garcia vs Harry Byrd | Second | 10½ out |
| Sunday, September 20 |
| » Lost to Tigers (59-90), 8-6 | Tiger Stadium (4-6) | 87-61 | |
| » Starters: Early Wynn vs Billy Hoeft | Second | 10½ out |
| » Defeated Tigers (59-91), 6-3 | Tiger Stadium (5-6) | 88-61 | |
| » Starters: Mike Garcia vs Ralph Branca | Second | 10½ out |
| Tuesday, September 22 |
| » Defeated White Sox (86-64), 8-3 | Comiskey Park I (4-6) | 89-61 | Won 2 |
| » Starters: Bob Feller vs Billy Pierce | Second | 10½ out |
| Wednesday, September 23 |
| » Defeated White Sox (86-65), 8-3 | Comiskey Park I (5-6) | 90-61 | Won 3 |
| » Starters: Bob Lemon vs Saul Rogovin | Second | 10½ out |
| Friday, September 25 |
| » Defeated Tigers (59-93), 12-3 | Cleveland Stadium (52-23) | 91-61 | Won 4 |
| » Starters: Steve Gromek vs Dick Tomanek | Second | 9½ out |
| » Major-league debuts: Dick Tomanek (Indians) |
| Saturday, September 26 |
| » Defeated Tigers (59-94), 12-3 | Cleveland Stadium (53-23) | 92-61 | Won 5 |
| » Starters: Ted Gray vs Dave Hoskins | Second | 8½ out |
| Sunday, September 27 |
| » Lost to Tigers (60-94), 7-3 | Cleveland Stadium (53-24) | 92-62 | |
| » Starters: Al Aber vs Bob Feller | Second | 8½ out |
| Tuesday, October 20 |
| Future Indian Keith Hernandez is born in San Francisco, CA. |
| Wednesday, October 21 |
| Future Indian Juan Eichelberger is born in St. Louis, MO. |
| Thursday, December 24 |
| Former Indian Pinch Thomas dies in Modesto, CA at the age of 66. |
Game information provided by Retrosheet (www.retrosheet.org) |
