| Tuesday, January 1 |
| Former White Sox Hi Bithorn dies in ElMante, Mexico at the age of 36. |
| Monday, January 14 |
| Future White Sox Terry Forster is born in Sioux Falls, SD. |
| Saturday, February 2 |
| Future White Sox Warren Brusstar is born in Oakland, CA. |
| Saturday, February 16 |
| Future White Sox Jerry Hairston is born in Birmingham, AL. |
| Monday, February 18 |
| Future White Sox Marc Hill is born in Elsberry, MO. |
| Wednesday, March 5 |
| Future White Sox Mike Squires is born in Kalamazoo, MI. |
| Tuesday, April 15 |
| » Lost to Indians (1-0), 3-2 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Early Wynn vs Billy Pierce | Third | 1 out |
| » Major-league debuts: George Wilson (White Sox) Jim Fridley (Indians) |
| Wednesday, April 16 |
| » Lost to Indians (2-0), 1-0 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » Starters: Bob Lemon vs Joe Dobson | Fifth | 2 out |
| Thursday, April 17 |
| » Lost to Indians (3-0), 5-3 | Comiskey Park I (0-3) | 0-3 | Lost 3 |
| » Starters: Mike Garcia vs Marv Grissom | Fifth | 3 out |
| Friday, April 18 |
| » Lost to Browns (4-0), 7-1 | Sportsman's Park III (0-1) | 0-4 | Lost 4 |
| » Starters: Chuck Stobbs vs Duane Pillette | Fifth | 4 out |
| Saturday, April 19 |
| » Defeated Browns (4-1), 8-3 | Sportsman's Park III (1-1) | 1-4 | |
| » Starters: Saul Rogovin vs Johnny Hetki | Sixth | 4 out |
| Sunday, April 20 |
| » Lost to Browns (5-1), 8-0 | Sportsman's Park III (1-2) | 1-5 | |
| » Starters: Ken Holcombe vs Ned Garver | Sixth | 5 out |
| » Defeated Browns (5-2), 10-5 | Sportsman's Park III (2-2) | 2-5 | |
| » Starters: Billy Pierce vs Cliff Fannin | Sixth | 5 out |
| » Major-league debuts: Darrell Johnson (Browns) |
| Monday, April 21 |
| » Major-league debuts: Ron Kline and Lee Walls (Pirates) |
| Tuesday, April 22 |
| » Defeated Tigers (0-8), 2-0 | Comiskey Park I (1-3) | 3-5 | Won 2 |
| » Starters: Ted Gray vs Saul Rogovin | Sixth | 4 out |
| Friday, April 25 |
| » Lost to Indians (8-2), 5-4 | Cleveland Stadium (0-1) | 3-6 | |
| » Starters: Billy Pierce vs Early Wynn | Sixth | 5 out |
| Saturday, April 26 |
| » Defeated Browns (7-3), 5-0 | Comiskey Park I (2-3) | 4-6 | |
| » Starters: Duane Pillette vs Joe Dobson | Sixth | 4½ out |
| Sunday, April 27 |
| » Defeated Browns (7-4), 7-6 | Comiskey Park I (3-3) | 5-6 | Won 2 |
| » Starters: Ned Garver vs Saul Rogovin | Fifth | 3½ out |
| » Defeated Browns (7-5), 6-3 | Comiskey Park I (4-3) | 6-6 | Won 3 |
| » Starters: Tommy Byrne vs Chuck Stobbs | Fifth | 3½ out |
| Wednesday, April 30 |
| » Defeated Senators (4-5), 7-3 | Griffith Stadium (1-0) | 7-6 | Won 4 |
| » Starters: Billy Pierce vs Bob Porterfield | Third | 3 out |
| » Defeated Senators (4-6), 4-3 | Griffith Stadium (2-0) | 8-6 | Won 5 |
| » Starters: Ken Holcombe vs Connie Marrero | Third | 3 out |
| Thursday, May 1 |
| » Defeated Athletics (2-9), 3-0 | Shibe Park (1-0) | 9-6 | Won 6 |
| » Starters: Joe Dobson vs Bob Hooper | Second | 2 out |
| Former White Sox Ernie Johnson dies in Monrovia, CA at the age of 65. |
| Friday, May 2 |
| » Lost to Athletics (3-9), 13-12 | Shibe Park (1-1) | 9-7 | |
| » Starters: Lou Kretlow vs Morrie Martin | Third | 3 out |
| Saturday, May 3 |
| » Lost to Athletics (4-9), 7-1 | Shibe Park (1-2) | 9-8 | Lost 2 |
| » Starters: Saul Rogovin vs Alex Kellner | Third | 4 out |
| Sunday, May 4 |
| » Lost to Yankees (7-8), 8-0 | Yankee Stadium (0-1) | 9-9 | Lost 3 |
| » Starters: Marv Grissom vs Tom Morgan | Fifth | 4½ out |
| » Lost to Yankees (8-8), 3-1 | Yankee Stadium (0-2) | 9-10 | Lost 4 |
| » Starters: Billy Pierce vs Bill Miller | Fifth | 4½ out |
| Tuesday, May 6 |
| » Lost to Red Sox (13-5), 11-2 | Fenway Park (0-1) | 9-11 | Lost 5 |
| » Starters: Joe Dobson vs Willard Nixon | Sixth | 5 out |
| Wednesday, May 7 |
| » Lost to Red Sox (14-5), 7-2 | Fenway Park (0-2) | 9-12 | Lost 6 |
| » Starters: Ken Holcombe vs Bill Henry | Sixth | 6 out |
| Thursday, May 8 |
| » Defeated Red Sox (14-6), 4-2 | Fenway Park (1-2) | 10-12 | |
| » Starters: Saul Rogovin vs Ray Scarborough | Fifth | 5 out |
| Friday, May 9 |
| » Defeated Tigers (4-15), 8-5 | Tiger Stadium (1-0) | 11-12 | Won 2 |
| » Starters: Billy Pierce vs Virgil Trucks | Fourth | 4½ out |
| Saturday, May 10 |
| » Defeated Tigers (4-16), 6-3 | Tiger Stadium (2-0) | 12-12 | Won 3 |
| » Starters: Joe Dobson vs Art Houtteman | Fourth | 3½ out |
| Sunday, May 11 |
| » Defeated Tigers (4-17), 6-5 | Tiger Stadium (3-0) | 13-12 | Won 4 |
| » Starters: Chuck Stobbs vs Hal Newhouser | Fifth | 4½ out |
| » Lost to Tigers (5-17), 2-1 | Tiger Stadium (3-1) | 13-13 | |
| » Starters: Marv Grissom vs Ted Gray | Fifth | 4½ out |
| Tuesday, May 13 |
| » Defeated Red Sox (14-10), 5-0 | Comiskey Park I (5-3) | 14-13 | |
| » Starters: Willard Nixon vs Billy Pierce | Fourth | 4½ out |
| Wednesday, May 14 |
| » Defeated Red Sox (14-11), 6-3 | Comiskey Park I (6-3) | 15-13 | Won 2 |
| » Starters: Bill Henry vs Saul Rogovin | Fourth | 3½ out |
| Thursday, May 15 |
| » Lost to Red Sox (15-11), 1-0 | Comiskey Park I (6-4) | 15-14 | |
| » Starters: Ray Scarborough vs Ken Holcombe | Fourth | 4 out |
| Sunday, May 18 |
| » Lost to Senators (16-11), 2-1 | Comiskey Park I (6-5) | 15-15 | Lost 2 |
| » Starters: Lou Sleater vs Saul Rogovin | Fifth | 4 out |
| » Defeated Senators (16-12), 6-4 | Comiskey Park I (7-5) | 16-15 | |
| » Starters: Don Johnson vs Joe Dobson | Fifth | 4 out |
| Tuesday, May 20 |
| » Lost to Yankees (15-13), 4-3 | Comiskey Park I (7-6) | 16-16 | |
| » Starters: Johnny Sain vs Ken Holcombe | Fifth | 4½ out |
| Wednesday, May 21 |
| » Lost to Yankees (16-13), 5-1 | Comiskey Park I (7-7) | 16-17 | Lost 2 |
| » Starters: Allie Reynolds vs Billy Pierce | Sixth | 5½ out |
| Friday, May 23 |
| » Lost to Tigers (9-21), 9-2 | Comiskey Park I (7-8) | 16-18 | Lost 3 |
| » Starters: Ted Gray vs Saul Rogovin | Fifth | 6 out |
| Sunday, May 25 |
| » Defeated Tigers (9-22), 3-0 | Comiskey Park I (8-8) | 17-18 | |
| » Starters: Virgil Trucks vs Joe Dobson | Fourth | 5½ out |
| » Defeated Tigers (9-23), 1-0 | Comiskey Park I (9-8) | 18-18 | Won 2 |
| » Starters: Art Houtteman vs Marv Grissom | Fourth | 5½ out |
| Monday, May 26 |
| » Defeated Browns (18-23), 6-2 | Sportsman's Park III (3-2) | 19-18 | Won 3 |
| » Starters: Billy Pierce vs Earl Harrist | Fourth | 5 out |
| Tuesday, May 27 |
| » Defeated Browns (18-24), 3-0 | Sportsman's Park III (4-2) | 20-18 | Won 4 |
| » Starters: Saul Rogovin vs Ned Garver | Fourth | 4 out |
| Wednesday, May 28 |
| » Lost to Browns (19-24), 3-1 | Sportsman's Park III (4-3) | 20-19 | |
| » Starters: Chuck Stobbs vs Bob Cain | Fourth | 4 out |
| Friday, May 30 |
| » Defeated Indians (25-16), 7-2 | Cleveland Stadium (1-1) | 21-19 | |
| » Starters: Billy Pierce vs Early Wynn | Fourth | 2½ out |
| » Defeated Indians (25-17), 3-1 | Cleveland Stadium (2-1) | 22-19 | Won 2 |
| » Starters: Joe Dobson vs Sam Jones | Fourth | 2½ out |
| Saturday, May 31 |
| » Defeated Red Sox (22-17), 7-3 | Fenway Park (2-2) | 23-19 | Won 3 |
| » Starters: Marv Grissom vs Ray Scarborough | Fourth | 2 out |
| Sunday, June 1 |
| » Lost to Red Sox (23-17), 3-2 | Fenway Park (2-3) | 23-20 | |
| » Starters: Saul Rogovin vs Bill Henry | Fourth | 2½ out |
| Monday, June 2 |
| » Lost to Red Sox (24-17), 6-2 | Fenway Park (2-4) | 23-21 | Lost 2 |
| » Starters: Ken Holcombe vs Willard Nixon | Fifth | 2½ out |
| Tuesday, June 3 |
| » Lost to Yankees (20-17), 4-3 | Yankee Stadium (0-3) | 23-22 | Lost 3 |
| » Starters: Billy Pierce vs Vic Raschi | Fifth | 3½ out |
| Wednesday, June 4 |
| » Lost to Yankees (21-17), 6-3 | Yankee Stadium (0-4) | 23-23 | Lost 4 |
| » Starters: Joe Dobson vs Ed Lopat | Fifth | 3½ out |
| Thursday, June 5 |
| » Lost to Yankees (22-17), 6-4 | Yankee Stadium (0-5) | 23-24 | Lost 5 |
| » Starters: Saul Rogovin vs Johnny Sain | Fifth | 4½ out |
| Friday, June 6 |
| » Defeated Senators (23-20), 4-3 | Griffith Stadium (3-0) | 24-24 | |
| » Starters: Marv Grissom vs Spec Shea | Fifth | 4½ out |
| Saturday, June 7 |
| » Defeated Senators (23-21), 5-3 | Griffith Stadium (4-0) | 25-24 | Won 2 |
| » Starters: Hal Brown vs Lou Sleater | Fifth | 4½ out |
| Sunday, June 8 |
| » Defeated Senators (23-22), 6-3 | Griffith Stadium (5-0) | 26-24 | Won 3 |
| » Starters: Ken Holcombe vs Julio Moreno | Fourth | 3 out |
| Tuesday, June 10 |
| » Defeated Athletics (20-23), 15-4 | Shibe Park (2-2) | 27-24 | Won 4 |
| » Starters: Billy Pierce vs Harry Byrd | Fourth | 3½ out |
| Wednesday, June 11 |
| » Lost to Athletics (21-23), 5-3 | Shibe Park (2-3) | 27-25 | |
| » Starters: Saul Rogovin vs Bob Hooper | Fourth | 3½ out |
| Thursday, June 12 |
| » Defeated Athletics (21-24), 10-4 | Shibe Park (3-3) | 28-25 | |
| » Starters: Marv Grissom vs Alex Kellner | Fourth | 3½ out |
| Saturday, June 14 |
| » Defeated Red Sox (31-22), 4-2 | Comiskey Park I (10-8) | 29-25 | Won 2 |
| » Starters: Mel Parnell vs Hal Brown | Fourth | 3 out |
| Sunday, June 15 |
| » Defeated Red Sox (31-23), 7-2 | Comiskey Park I (11-8) | 30-25 | Won 3 |
| » Starters: Willard Nixon vs Saul Rogovin | Fourth | 4 out |
| » Lost to Red Sox (32-23), 3-2 | Comiskey Park I (11-9) | 30-26 | |
| » Starters: Dizzy Trout vs Chuck Stobbs | Fourth | 4 out |
| » Major-league debuts: Dick Brodowski (Red Sox) |
| Tuesday, June 17 |
| » Defeated Athletics (22-27), 13-1 | Comiskey Park I (12-9) | 31-26 | |
| » Starters: Alex Kellner vs Billy Pierce | Third | 3½ out |
| » Defeated Athletics (22-28), 2-1 | Comiskey Park I (13-9) | 32-26 | Won 2 |
| » Starters: Sam Zoldak vs Marv Grissom | Third | 3½ out |
| Thursday, June 19 |
| » Lost to Athletics (23-28), 4-1 | Comiskey Park I (13-10) | 32-27 | |
| » Starters: Bobby Shantz vs Hal Brown | Third | 3½ out |
| » Defeated Athletics (23-29), 5-4 | Comiskey Park I (14-10) | 33-27 | |
| » Starters: Bob Hooper vs Joe Dobson | Third | 3½ out |
| Friday, June 20 |
| » Defeated Yankees (33-21), 8-5 | Comiskey Park I (15-10) | 34-27 | Won 2 |
| » Starters: Vic Raschi vs Saul Rogovin | Third | 3½ out |
| Saturday, June 21 |
| » Defeated Yankees (33-22), 5-1 | Comiskey Park I (16-10) | 35-27 | Won 3 |
| » Starters: Ed Lopat vs Chuck Stobbs | Third | 3½ out |
| Sunday, June 22 |
| » Lost to Yankees (34-22), 3-0 | Comiskey Park I (16-11) | 35-28 | |
| » Starters: Bob Kuzava vs Billy Pierce | Second | 3½ out |
| » Defeated Yankees (34-23), 2-1 | Comiskey Park I (17-11) | 36-28 | |
| » Starters: Bill Miller vs Marv Grissom | Second | 3½ out |
| Future White Sox Randy Scarbery is born in Fresno, CA. |
| Monday, June 23 |
| » Lost to Senators (30-28), 6-4 | Comiskey Park I (17-12) | 36-29 | |
| » Starters: Spec Shea vs Hal Brown | Third | 3½ out |
| Tuesday, June 24 |
| » Lost to Senators (31-28), 6-2 | Comiskey Park I (17-13) | 36-30 | Lost 2 |
| » Starters: Julio Moreno vs Joe Dobson | Fourth | 3½ out |
| Wednesday, June 25 |
| » Lost to Senators (32-28), 9-6 | Comiskey Park I (17-14) | 36-31 | Lost 3 |
| » Starters: Lou Sleater vs Saul Rogovin | Fourth | 3½ out |
| Friday, June 27 |
| » Defeated Indians (36-31), 5-1 | Comiskey Park I (18-14) | 37-31 | |
| » Starters: Bob Feller vs Billy Pierce | Third | 3½ out |
| Saturday, June 28 |
| » Lost to Indians (37-31), 5-1 | Comiskey Park I (18-15) | 37-32 | |
| » Starters: Mike Garcia vs Chuck Stobbs | Fifth | 3½ out |
| Sunday, June 29 |
| » Defeated Indians (37-32), 4-2 | Comiskey Park I (19-15) | 38-32 | |
| » Starters: Early Wynn vs Saul Rogovin | Second | 4 out |
| » Tied Indians, 7-7 | Comiskey Park I (19-15) | 38-32 | |
| » Starters: Bob Lemon vs Marv Grissom | Second | 4 out |
| Monday, June 30 |
| » Defeated Tigers (22-46), 7-2 | Tiger Stadium (4-1) | 39-32 | Won 2 |
| » Starters: Joe Dobson vs Art Houtteman | Second | 3 out |
| Tuesday, July 1 |
| » Lost to Tigers (23-46), 6-4 | Tiger Stadium (4-2) | 39-33 | |
| » Starters: Lou Kretlow vs Bill Wight | Fourth | 4 out |
| Wednesday, July 2 |
| » Defeated Tigers (23-47), 3-2 | Tiger Stadium (5-2) | 40-33 | |
| » Starters: Billy Pierce vs Hal Newhouser | Third | 3 out |
| Thursday, July 3 |
| » Defeated Browns (32-41), 12-3 | Comiskey Park I (20-15) | 41-33 | Won 2 |
| » Starters: Earl Harrist vs Marv Grissom | Second | 2½ out |
| Friday, July 4 |
| » Defeated Browns (32-42), 3-1 | Comiskey Park I (21-15) | 42-33 | Won 3 |
| » Starters: Duane Pillette vs Lou Kretlow | Second | 2½ out |
| » Defeated Browns (32-43), 2-0 | Comiskey Park I (22-15) | 43-33 | Won 4 |
| » Starters: Stubby Overmire vs Saul Rogovin | Second | 2½ out |
| Saturday, July 5 |
| » Lost to Indians (42-32), 3-2 | Cleveland Stadium (2-2) | 43-34 | |
| » Starters: Joe Dobson vs Bob Feller | Third | 3½ out |
| Sunday, July 6 |
| » Defeated Indians (42-33), 3-2 | Cleveland Stadium (3-2) | 44-34 | |
| » Starters: Billy Pierce vs Mike Garcia | Second | 3 out |
| Thursday, July 10 |
| » Defeated Senators (39-35), 2-0 | Griffith Stadium (6-0) | 45-34 | Won 2 |
| » Starters: Billy Pierce vs Bob Porterfield | Second | 2½ out |
| » Defeated Senators (39-36), 4-2 | Griffith Stadium (7-0) | 46-34 | Won 3 |
| » Starters: Saul Rogovin vs Walt Masterson | Second | 2½ out |
| Friday, July 11 |
| » Lost to Senators (40-36), 2-1 | Griffith Stadium (7-1) | 46-35 | |
| » Starters: Joe Dobson vs Spec Shea | Second | 2½ out |
| Saturday, July 12 |
| » Lost to Senators (41-36), 2-1 | Griffith Stadium (7-2) | 46-36 | Lost 2 |
| » Starters: Chuck Stobbs vs Julio Moreno | Third | 3½ out |
| Sunday, July 13 |
| » Lost to Athletics (33-39), 6-0 | Shibe Park (3-4) | 46-37 | Lost 3 |
| » Starters: Lou Kretlow vs Bobby Shantz | Third | 4½ out |
| » Defeated Athletics (33-40), 7-4 | Shibe Park (4-4) | 47-37 | |
| » Starters: Marv Grissom vs Bob Hooper | Third | 4½ out |
| Monday, July 14 |
| » Lost to Athletics (34-40), 2-1 | Shibe Park (4-5) | 47-38 | |
| » Starters: Billy Pierce vs Harry Byrd | Third | 4½ out |
| Tuesday, July 15 |
| » Lost to Red Sox (45-37), 7-5 | Fenway Park (2-5) | 47-39 | Lost 2 |
| » Starters: Saul Rogovin vs Dick Brodowski | Fourth | 4½ out |
| Wednesday, July 16 |
| » Lost to Red Sox (46-37), 7-3 | Fenway Park (2-6) | 47-40 | Lost 3 |
| » Starters: Joe Dobson vs Mel Parnell | Fourth | 6 out |
| Thursday, July 17 |
| » Lost to Red Sox (47-37), 2-1 | Fenway Park (2-7) | 47-41 | Lost 4 |
| » Starters: Marv Grissom vs Dizzy Trout | Fifth | 6½ out |
| Friday, July 18 |
| » Lost to Yankees (53-33), 6-3 | Yankee Stadium (0-6) | 47-42 | Lost 5 |
| » Starters: Chuck Stobbs vs Tom Gorman | Fifth | 7½ out |
| Saturday, July 19 |
| » Lost to Yankees (54-33), 4-2 | Yankee Stadium (0-7) | 47-43 | Lost 6 |
| » Starters: Billy Pierce vs Tom Morgan | Fifth | 8½ out |
| Sunday, July 20 |
| » Defeated Yankees (54-34), 5-4 | Yankee Stadium (1-7) | 48-43 | |
| » Starters: Saul Rogovin vs Bob Kuzava | Fifth | 7½ out |
| Tuesday, July 22 |
| » Lost to Red Sox (50-38), 4-2 | Comiskey Park I (22-16) | 48-44 | |
| » Starters: Mel Parnell vs Marv Grissom | Fifth | 9 out |
| Wednesday, July 23 |
| » Lost to Red Sox (51-38), 10-4 | Comiskey Park I (22-17) | 48-45 | Lost 2 |
| » Starters: Sid Hudson vs Hal Brown | Fifth | 9 out |
| Thursday, July 24 |
| » Defeated Red Sox (51-39), 3-0 | Comiskey Park I (23-17) | 49-45 | |
| » Starters: Dizzy Trout vs Lou Kretlow | Fifth | 8 out |
| Friday, July 25 |
| » Defeated Athletics (41-44), 5-0 | Comiskey Park I (24-17) | 50-45 | Won 2 |
| » Starters: Harry Byrd vs Billy Pierce | Fifth | 7½ out |
| » Lost to Athletics (42-44), 5-4 | Comiskey Park I (24-18) | 50-46 | |
| » Starters: Carl Scheib vs Saul Rogovin | Fifth | 7½ out |
| Saturday, July 26 |
| » Defeated Athletics (42-45), 9-3 | Comiskey Park I (25-18) | 51-46 | |
| » Starters: Bobo Newsom vs Chuck Stobbs | Fifth | 6½ out |
| Sunday, July 27 |
| » Lost to Athletics (43-45), 3-1 | Comiskey Park I (25-19) | 51-47 | |
| » Starters: Bobby Shantz vs Joe Dobson | Fifth | 7½ out |
| » Lost to Athletics (44-45), 9-3 | Comiskey Park I (25-20) | 51-48 | Lost 2 |
| » Starters: Alex Kellner vs Marv Grissom | Fifth | 7½ out |
| Tuesday, July 29 |
| » Lost to Yankees (58-40), 10-7 | Comiskey Park I (25-21) | 51-49 | Lost 3 |
| » Starters: Jim McDonald vs Billy Pierce | Fifth | 8 out |
| Wednesday, July 30 |
| » Defeated Yankees (58-41), 7-0 | Comiskey Park I (26-21) | 52-49 | |
| » Starters: Bob Kuzava vs Lou Kretlow | Fifth | 7 out |
| Thursday, July 31 |
| » Lost to Yankees (59-41), 6-2 | Comiskey Park I (26-22) | 52-50 | |
| » Starters: Vic Raschi vs Saul Rogovin | Sixth | 8 out |
| Friday, August 1 |
| » Lost to Senators (54-46), 3-1 | Comiskey Park I (26-23) | 52-51 | Lost 2 |
| » Starters: Walt Masterson vs Joe Dobson | Fifth | 8 out |
| Former White Sox Phil Douglas dies in Sequatchie, TN at the age of 63. |
| Saturday, August 2 |
| » Defeated Senators (54-47), 6-1 | Comiskey Park I (27-23) | 53-51 | |
| » Starters: Julio Moreno vs Chuck Stobbs | Fifth | 7 out |
| Sunday, August 3 |
| » Tied Senators, 0-0 | Comiskey Park I (27-23) | 53-51 | |
| » Starters: Connie Marrero vs Billy Pierce | Fifth | 8 out |
| Tuesday, August 5 |
| » Lost to Indians (59-46), 6-0 | Comiskey Park I (27-24) | 53-52 | |
| » Starters: Bob Lemon vs Lou Kretlow | Sixth | 9 out |
| » Defeated Indians (59-47), 6-3 | Comiskey Park I (28-24) | 54-52 | |
| » Starters: Mike Garcia vs Saul Rogovin | Sixth | 9 out |
| Wednesday, August 6 |
| » Lost to Indians (60-47), 7-1 | Comiskey Park I (28-25) | 54-53 | |
| » Starters: Early Wynn vs Bill Kennedy | Sixth | 9 out |
| Friday, August 8 |
| » Defeated Tigers (36-71), 4-3 | Comiskey Park I (29-25) | 55-53 | |
| » Starters: Billy Hoeft vs Billy Pierce | Sixth | 8 out |
| » Defeated Tigers (36-72), 2-1 | Comiskey Park I (30-25) | 56-53 | Won 2 |
| » Starters: Art Houtteman vs Joe Dobson | Sixth | 8 out |
| Saturday, August 9 |
| » Lost to Tigers (37-72), 6-1 | Comiskey Park I (30-26) | 56-54 | |
| » Starters: Hal Newhouser vs Marv Grissom | Sixth | 8 out |
| Sunday, August 10 |
| » Defeated Tigers (37-73), 3-1 | Comiskey Park I (31-26) | 57-54 | |
| » Starters: Ted Gray vs Lou Kretlow | Fifth | 7 out |
| » Defeated Tigers (37-74), 5-4 | Comiskey Park I (32-26) | 58-54 | Won 2 |
| » Starters: Virgil Trucks vs Saul Rogovin | Fifth | 7 out |
| Tuesday, August 12 |
| » Lost to Browns (48-65), 3-2 | Sportsman's Park III (4-4) | 58-55 | |
| » Starters: Chuck Stobbs vs Gene Bearden | Sixth | 8 out |
| Wednesday, August 13 |
| » Defeated Tigers (37-75), 7-1 | Tiger Stadium (6-2) | 59-55 | |
| » Starters: Joe Dobson vs Bill Wight | Fifth | 7½ out |
| Thursday, August 14 |
| » Defeated Tigers (37-76), 2-0 | Tiger Stadium (7-2) | 60-55 | Won 2 |
| » Starters: Marv Grissom vs Art Houtteman | Fourth | 7½ out |
| Saturday, August 16 |
| » Lost to Indians (65-49), 4-3 | Cleveland Stadium (3-3) | 60-56 | |
| » Starters: Billy Pierce vs Bob Lemon | Fifth | 8 out |
| Sunday, August 17 |
| » Lost to Indians (66-49), 6-2 | Cleveland Stadium (3-4) | 60-57 | Lost 2 |
| » Starters: Lou Kretlow vs Bob Feller | Fifth | 9½ out |
| » Lost to Indians (67-49), 2-1 | Cleveland Stadium (3-5) | 60-58 | Lost 3 |
| » Starters: Chuck Stobbs vs Mike Garcia | Fifth | 9½ out |
| Tuesday, August 19 |
| » Defeated Yankees (70-49), 3-1 | Yankee Stadium (2-7) | 61-58 | |
| » Starters: Marv Grissom vs Johnny Schmitz | Fifth | 9 out |
| » Major-league debuts: Loren Babe (Yankees) |
| Wednesday, August 20 |
| » Defeated Yankees (70-50), 12-3 | Yankee Stadium (3-7) | 62-58 | Won 2 |
| » Starters: Saul Rogovin vs Johnny Sain | Fifth | 8 out |
| Thursday, August 21 |
| » Defeated Yankees (70-51), 6-1 | Yankee Stadium (4-7) | 63-58 | Won 3 |
| » Starters: Billy Pierce vs Tom Gorman | Fifth | 7 out |
| Friday, August 22 |
| » Defeated Red Sox (63-54), 4-1 | Fenway Park (3-7) | 64-58 | Won 4 |
| » Starters: Joe Dobson vs Ike Delock | Fourth | 6 out |
| Saturday, August 23 |
| » Lost to Red Sox (64-54), 4-3 | Fenway Park (3-8) | 64-59 | |
| » Starters: Hal Brown vs Mel Parnell | Fifth | 7 out |
| Sunday, August 24 |
| » Defeated Athletics (62-58), 11-7 | Shibe Park (5-5) | 65-59 | |
| » Starters: Marv Grissom vs Harry Byrd | Fifth | 7½ out |
| » Lost to Athletics (63-58), 5-1 | Shibe Park (5-6) | 65-60 | |
| » Starters: Chuck Stobbs vs Carl Scheib | Fifth | 7½ out |
| Tuesday, August 26 |
| » Lost to Senators (65-60), 1-0 | Griffith Stadium (7-3) | 65-61 | Lost 2 |
| » Starters: Billy Pierce vs Bob Porterfield | Fifth | 8 out |
| Wednesday, August 27 |
| » Defeated Senators (65-61), 4-1 | Griffith Stadium (8-3) | 66-61 | |
| » Starters: Chuck Stobbs vs Julio Moreno | Fourth | 8 out |
| Saturday, August 30 |
| » Defeated Indians (73-56), 11-6 | Comiskey Park I (33-26) | 67-61 | Won 2 |
| » Starters: Bob Feller vs Hal Brown | Fifth | 7½ out |
| Sunday, August 31 |
| » Lost to Indians (74-56), 6-3 | Comiskey Park I (33-27) | 67-62 | |
| » Starters: Mike Garcia vs Billy Pierce | Fifth | 8½ out |
| Tuesday, September 2 |
| » Defeated Tigers (43-88), 6-5 | Comiskey Park I (34-27) | 68-62 | |
| » Starters: Ted Gray vs Joe Dobson | Fourth | 9 out |
| » Defeated Tigers (43-89), 7-4 | Comiskey Park I (35-27) | 69-62 | Won 2 |
| » Starters: Billy Hoeft vs Marv Grissom | Fourth | 9 out |
| Wednesday, September 3 |
| » Defeated Browns (55-79), 1-0 | Comiskey Park I (36-27) | 70-62 | Won 3 |
| » Starters: Dick Littlefield vs Saul Rogovin | Third | 8 out |
| Thursday, September 4 |
| » Lost to Browns (56-79), 8-0 | Comiskey Park I (36-28) | 70-63 | |
| » Starters: Duane Pillette vs Chuck Stobbs | Fourth | 9 out |
| Friday, September 5 |
| » Lost to Indians (77-58), 3-0 | Cleveland Stadium (3-6) | 70-64 | Lost 2 |
| » Starters: Billy Pierce vs Early Wynn | Fifth | 9 out |
| Saturday, September 6 |
| » Defeated Tigers (44-91), 4-3 | Tiger Stadium (8-2) | 71-64 | |
| » Starters: Joe Dobson vs Virgil Trucks | Fourth | 9 out |
| » Major-league debuts: Harvey Kuenn (Tigers) |
| Sunday, September 7 |
| » Lost to Tigers (45-91), 4-2 | Tiger Stadium (8-3) | 71-65 | |
| » Starters: Marv Grissom vs Ted Gray | Fifth | 10 out |
| Tuesday, September 9 |
| » Defeated Senators (72-67), 3-2 | Comiskey Park I (37-28) | 72-65 | |
| » Starters: Bob Porterfield vs Saul Rogovin | Third | 8½ out |
| » Defeated Senators (72-68), 3-2 | Comiskey Park I (38-28) | 73-65 | Won 2 |
| » Starters: Mike Fornieles vs Harry Dorish | Third | 8½ out |
| Wednesday, September 10 |
| » Defeated Senators (72-69), 6-3 | Comiskey Park I (39-28) | 74-65 | Won 3 |
| » Starters: Raul Sanchez vs Billy Pierce | Third | 8½ out |
| Thursday, September 11 |
| » Lost to Senators (73-69), 4-1 | Comiskey Park I (39-29) | 74-66 | |
| » Starters: Walt Masterson vs Joe Dobson | Third | 9 out |
| Friday, September 12 |
| » Lost to Yankees (84-57), 6-4 | Comiskey Park I (39-30) | 74-67 | Lost 2 |
| » Starters: Tom Gorman vs Hal Brown | Third | 10 out |
| Saturday, September 13 |
| » Lost to Yankees (85-57), 6-5 | Comiskey Park I (39-31) | 74-68 | Lost 3 |
| » Starters: Vic Raschi vs Marv Grissom | Third | 11 out |
| Sunday, September 14 |
| » Defeated Red Sox (73-69), 4-3 | Comiskey Park I (40-31) | 75-68 | |
| » Starters: Dizzy Trout vs Saul Rogovin | Third | 11 out |
| Monday, September 15 |
| » Defeated Red Sox (73-70), 4-2 | Comiskey Park I (41-31) | 76-68 | Won 2 |
| » Starters: Mel Parnell vs Lou Kretlow | Third | 10½ out |
| Tuesday, September 16 |
| » Lost to Athletics (76-70), 2-1 | Comiskey Park I (41-32) | 76-69 | |
| » Starters: Harry Byrd vs Billy Pierce | Third | 11 out |
| » Defeated Athletics (76-71), 7-1 | Comiskey Park I (42-32) | 77-69 | |
| » Starters: Carl Scheib vs Joe Dobson | Third | 11 out |
| Former White Sox Earl Sheely dies in Seattle, WA at the age of 60. |
| Saturday, September 20 |
| » Lost to Browns (60-86), 9-6 | Sportsman's Park III (4-5) | 77-70 | |
| » Starters: Saul Rogovin vs Dick Littlefield | Third | 12½ out |
| » Lost to Browns (61-86), 4-0 | Sportsman's Park III (4-6) | 77-71 | Lost 2 |
| » Starters: Marv Grissom vs Satchel Paige | Third | 12½ out |
| Sunday, September 21 |
| » Defeated Browns (61-87), 4-1 | Sportsman's Park III (5-6) | 78-71 | |
| » Starters: Billy Pierce vs Gene Bearden | Third | 12½ out |
| Tuesday, September 23 |
| » Defeated Indians (90-61), 10-1 | Cleveland Stadium (4-6) | 79-71 | Won 2 |
| » Starters: Joe Dobson vs Mike Garcia | Third | 12 out |
| Future White Sox Dennis Lamp is born in Los Angeles, CA. Future White Sox Jim Morrison is born in Pensacola, FL. |
| Wednesday, September 24 |
| » Lost to Indians (91-61), 6-0 | Cleveland Stadium (4-7) | 79-72 | |
| » Starters: Lou Kretlow vs Bob Lemon | Third | 13½ out |
| Thursday, September 25 |
| Future White Sox Mike Stanton is born in Phenix City, AL. |
| Friday, September 26 |
| » Defeated Browns (63-89), 6-2 | Comiskey Park I (43-32) | 80-72 | |
| » Starters: Satchel Paige vs Saul Rogovin | Third | 14 out |
| Saturday, September 27 |
| » Defeated Browns (63-90), 8-4 | Comiskey Park I (44-32) | 81-72 | Won 2 |
| » Starters: Bob Cain vs Marv Grissom | Third | 14 out |
| Sunday, September 28 |
| » Lost to Browns (64-90), 12-1 | Comiskey Park I (44-33) | 81-73 | |
| » Starters: Duane Pillette vs Chuck Stobbs | Third | 14 out |
| » Major-league debuts: Sammy Esposito (White Sox) |
