| Thursday, January 10 |
| Former Senator Bones Ely dies in Berkeley, CA at the age of 89. |
| Sunday, January 20 |
| Former Senator Ollie Pickering dies in Vincennes, IN at the age of 82. |
| Sunday, March 23 |
| Former Senator Steve Sundra dies in Cleveland, OH at the age of 42. |
| Tuesday, April 15 |
| » Lost to Red Sox (1-0), 3-0 | Griffith Stadium (0-1) | 0-1 | |
| » Starters: Mel Parnell vs Bob Porterfield | Third | 1 out |
| » Major-league debuts: Ted Lepcio and Faye Throneberry (Red Sox) |
| Wednesday, April 16 |
| » Defeated Red Sox (1-1), 4-3 | Griffith Stadium (1-1) | 1-1 | |
| » Starters: Randy Gumpert vs Julio Moreno | Third | 1 out |
| » Major-league debuts: Dick Gernert and Gene Stephens (Red Sox) |
| Thursday, April 17 |
| » Lost to Red Sox (2-1), 9-2 | Griffith Stadium (1-2) | 1-2 | |
| » Starters: Bill Henry vs Don Johnson | Fourth | 2 out |
| » Major-league debuts: Raul Sanchez (Senators) Ike Delock and Bill Henry (Red Sox) |
| Friday, April 18 |
| » Defeated Yankees (1-2), 3-1 | Yankee Stadium (1-0) | 2-2 | |
| » Starters: Connie Marrero vs Allie Reynolds | Third | 2 out |
| Saturday, April 19 |
| » Defeated Yankees (1-3), 2-0 | Yankee Stadium (2-0) | 3-2 | Won 2 |
| » Starters: Bob Porterfield vs Tom Morgan | Fourth | 2 out |
| Sunday, April 20 |
| » Lost to Red Sox (6-1), 6-3 | Fenway Park (0-1) | 3-3 | |
| » Starters: Sid Hudson vs Mel Parnell | Fourth | 3½ out |
| Monday, April 21 |
| » Defeated Red Sox (6-2), 3-2 | Fenway Park (1-1) | 4-3 | |
| » Starters: Julio Moreno vs James Atkins | Fourth | 3 out |
| Tuesday, April 22 |
| » Lost to Red Sox (7-2), 10-5 | Fenway Park (1-2) | 4-4 | |
| » Starters: Joe Haynes vs Bill Henry | Fifth | 3 out |
| Wednesday, April 30 |
| » Lost to White Sox (7-6), 7-3 | Griffith Stadium (1-3) | 4-5 | Lost 2 |
| » Starters: Billy Pierce vs Bob Porterfield | Fifth | 5 out |
| » Lost to White Sox (8-6), 4-3 | Griffith Stadium (1-4) | 4-6 | Lost 3 |
| » Starters: Ken Holcombe vs Connie Marrero | Fifth | 5 out |
| Thursday, May 1 |
| » Defeated Indians (9-6), 2-1 | Griffith Stadium (2-4) | 5-6 | |
| » Starters: Bob Lemon vs Sid Hudson | Third | 4 out |
| Friday, May 2 |
| » Lost to Indians (10-6), 6-2 | Griffith Stadium (2-5) | 5-7 | |
| » Starters: Mike Garcia vs Julio Moreno | Fifth | 5 out |
| Saturday, May 3 |
| » Defeated Indians (10-7), 7-6 | Griffith Stadium (3-5) | 6-7 | |
| » Starters: Bob Feller vs Don Johnson | Fourth | 5 out |
| Sunday, May 4 |
| » Defeated Browns (9-9), 2-1 | Griffith Stadium (4-5) | 7-7 | Won 2 |
| » Starters: Tommy Byrne vs Bob Porterfield | Third | 3½ out |
| » Defeated Browns (9-10), 15-7 | Griffith Stadium (5-5) | 8-7 | Won 3 |
| » Starters: Bob Cain vs Sandy Consuegra | Third | 3½ out |
| » Major-league debuts: Bunky Stewart (Senators) |
| Monday, May 5 |
| » Defeated Browns (9-11), 13-1 | Griffith Stadium (6-5) | 9-7 | Won 4 |
| » Starters: Ned Garver vs Spec Shea | Third | 2½ out |
| Tuesday, May 6 |
| » Defeated Tigers (4-13), 5-2 | Griffith Stadium (7-5) | 10-7 | Won 5 |
| » Starters: Art Houtteman vs Connie Marrero | Third | 2½ out |
| Wednesday, May 7 |
| » Defeated Tigers (4-14), 6-2 | Griffith Stadium (8-5) | 11-7 | Won 6 |
| » Starters: Ted Gray vs Sid Hudson | Third | 2½ out |
| Thursday, May 8 |
| » Tied Tigers, 4-4 | Griffith Stadium (8-5) | 11-7 | |
| » Starters: Marlin Stuart vs Don Johnson | Third | 2 out |
| » Major-league debuts: Jerry Snyder (Senators) |
| Friday, May 9 |
| » Lost to Athletics (8-11), 9-3 | Shibe Park (0-1) | 11-8 | |
| » Starters: Bob Porterfield vs Bobby Shantz | Third | 2½ out |
| Saturday, May 10 |
| » Defeated Athletics (8-12), 3-1 | Shibe Park (1-1) | 12-8 | |
| » Starters: Spec Shea vs Morrie Martin | Third | 1½ out |
| Sunday, May 11 |
| » Defeated Athletics (8-13), 5-2 | Shibe Park (2-1) | 13-8 | Won 2 |
| » Starters: Julio Moreno vs Alex Kellner | Second | 2 out |
| Tuesday, May 13 |
| » Defeated Tigers (5-18), 4-3 | Tiger Stadium (1-0) | 14-8 | Won 3 |
| » Starters: Connie Marrero vs Marlin Stuart | Second | 2 out |
| Wednesday, May 14 |
| » Lost to Tigers (6-18), 3-2 | Tiger Stadium (1-1) | 14-9 | |
| » Starters: Sid Hudson vs Art Houtteman | Second | 2 out |
| Thursday, May 15 |
| » Lost to Tigers (7-18), 1-0 | Tiger Stadium (1-2) | 14-10 | Lost 2 |
| » Starters: Bob Porterfield vs Virgil Trucks | Second | 2½ out |
| Friday, May 16 |
| » Defeated Indians (18-10), 2-0 | Cleveland Stadium (1-0) | 15-10 | |
| » Starters: Spec Shea vs Early Wynn | Second | 1½ out |
| Saturday, May 17 |
| » Lost to Indians (19-10), 9-2 | Cleveland Stadium (1-1) | 15-11 | |
| » Starters: Julio Moreno vs Bob Lemon | Second | 2½ out |
| Sunday, May 18 |
| » Defeated White Sox (15-15), 2-1 | Comiskey Park I (1-0) | 16-11 | |
| » Starters: Lou Sleater vs Saul Rogovin | Second | 2½ out |
| » Lost to White Sox (16-15), 6-4 | Comiskey Park I (1-1) | 16-12 | |
| » Starters: Don Johnson vs Joe Dobson | Second | 2½ out |
| Tuesday, May 20 |
| » Defeated Browns (16-18), 2-0 | Sportsman's Park III (1-0) | 17-12 | |
| » Starters: Connie Marrero vs Tommy Byrne | Second | 2 out |
| Wednesday, May 21 |
| » Lost to Browns (17-18), 2-1 | Sportsman's Park III (1-1) | 17-13 | |
| » Starters: Sid Hudson vs Earl Harrist | Second | 3 out |
| Thursday, May 22 |
| » Defeated Browns (17-19), 4-2 | Sportsman's Park III (2-1) | 18-13 | |
| » Starters: Bob Porterfield vs Gene Bearden | Second | 2 out |
| Sunday, May 25 |
| » Lost to Athletics (12-16), 2-1 | Griffith Stadium (8-6) | 18-14 | |
| » Starters: Bobby Shantz vs Julio Moreno | Second | 3 out |
| » Defeated Athletics (12-17), 1-0 | Griffith Stadium (9-6) | 19-14 | |
| » Starters: Bob Hooper vs Lou Sleater | Second | 3 out |
| Monday, May 26 |
| » Defeated Athletics (12-18), 5-3 | Griffith Stadium (10-6) | 20-14 | Won 2 |
| » Starters: Sam Zoldak vs Sid Hudson | Second | 2½ out |
| Tuesday, May 27 |
| » Lost to Yankees (17-15), 7-2 | Yankee Stadium (2-1) | 20-15 | |
| » Starters: Connie Marrero vs Allie Reynolds | Second | 2½ out |
| Thursday, May 29 |
| » Lost to Red Sox (21-15), 1-0 | Fenway Park (1-3) | 20-16 | Lost 2 |
| » Starters: Bob Porterfield vs Mickey McDermott | Third | 3 out |
| Former Senator Doc Lavan dies in Detroit, MI at the age of 62. |
| Friday, May 30 |
| » Defeated Red Sox (21-16), 5-2 | Fenway Park (2-3) | 21-16 | |
| » Starters: Spec Shea vs Ellis Kinder | Third | 2 out |
| » Lost to Red Sox (22-16), 5-3 | Fenway Park (2-4) | 21-17 | |
| » Starters: Julio Moreno vs Mel Parnell | Third | 2 out |
| Sunday, June 1 |
| » Defeated Tigers (12-26), 4-3 | Griffith Stadium (11-6) | 22-17 | |
| » Starters: Marlin Stuart vs Lou Sleater | Third | 2 out |
| » Lost to Tigers (13-26), 6-3 | Griffith Stadium (11-7) | 22-18 | |
| » Starters: Ted Gray vs Sid Hudson | Third | 2 out |
| Monday, June 2 |
| » Defeated Tigers (13-27), 5-2 | Griffith Stadium (12-7) | 23-18 | |
| » Starters: Art Houtteman vs Connie Marrero | Third | 1 out |
| Tuesday, June 3 |
| » Lost to Browns (21-26), 3-2 | Griffith Stadium (12-8) | 23-19 | |
| » Starters: Dave Madison vs Bob Porterfield | Third | 2 out |
| Friday, June 6 |
| » Lost to White Sox (24-24), 4-3 | Griffith Stadium (12-9) | 23-20 | Lost 2 |
| » Starters: Marv Grissom vs Spec Shea | Fourth | 3 out |
| Saturday, June 7 |
| » Lost to White Sox (25-24), 5-3 | Griffith Stadium (12-10) | 23-21 | Lost 3 |
| » Starters: Hal Brown vs Lou Sleater | Fourth | 4 out |
| Sunday, June 8 |
| » Lost to White Sox (26-24), 6-3 | Griffith Stadium (12-11) | 23-22 | Lost 4 |
| » Starters: Ken Holcombe vs Julio Moreno | Fifth | 3½ out |
| Tuesday, June 10 |
| » Lost to Indians (30-21), 4-3 | Griffith Stadium (12-12) | 23-23 | Lost 5 |
| » Starters: Early Wynn vs Connie Marrero | Fifth | 4 out |
| Wednesday, June 11 |
| » Defeated Indians (30-22), 1-0 | Griffith Stadium (13-12) | 24-23 | |
| » Starters: Bob Lemon vs Bob Porterfield | Fifth | 4 out |
| Thursday, June 12 |
| » Lost to Indians (31-22), 7-4 | Griffith Stadium (13-13) | 24-24 | |
| » Starters: Bob Feller vs Spec Shea | Fifth | 5 out |
| Saturday, June 14 |
| » Lost to Tigers (16-36), 7-6 | Tiger Stadium (1-3) | 24-25 | Lost 2 |
| » Starters: Lou Sleater vs Art Houtteman | Fifth | 5½ out |
| Sunday, June 15 |
| » Lost to Tigers (17-36), 6-3 | Tiger Stadium (1-4) | 24-26 | Lost 3 |
| » Starters: Randy Gumpert vs Ted Gray | Fifth | 6½ out |
| » Defeated Tigers (17-37), 4-2 | Tiger Stadium (2-4) | 25-26 | |
| » Starters: Walt Masterson vs Virgil Trucks | Fifth | 6½ out |
| Tuesday, June 17 |
| » Defeated Indians (32-26), 4-3 | Cleveland Stadium (2-1) | 26-26 | Won 2 |
| » Starters: Bob Porterfield vs Bob Feller | Fourth | 5½ out |
| Wednesday, June 18 |
| » Defeated Indians (32-27), 3-2 | Cleveland Stadium (3-1) | 27-26 | Won 3 |
| » Starters: Spec Shea vs Mike Garcia | Fifth | 5½ out |
| Thursday, June 19 |
| » Defeated Indians (32-28), 6-3 | Cleveland Stadium (4-1) | 28-26 | Won 4 |
| » Starters: Connie Marrero vs Early Wynn | Fifth | 5½ out |
| Friday, June 20 |
| » Tied Browns, 5-5 | Sportsman's Park III (2-1) | 28-26 | |
| » Starters: Lou Sleater vs Tommy Byrne | Fifth | 5 out |
| Saturday, June 21 |
| » Lost to Browns (28-33), 7-3 | Sportsman's Park III (2-2) | 28-27 | |
| » Starters: Walt Masterson vs Ned Garver | Fifth | 5 out |
| Sunday, June 22 |
| » Defeated Browns (28-34), 8-5 | Sportsman's Park III (3-2) | 29-27 | |
| » Starters: Randy Gumpert vs Earl Harrist | Fifth | 5 out |
| » Lost to Browns (29-34), 3-2 | Sportsman's Park III (3-3) | 29-28 | |
| » Starters: Bob Porterfield vs Gene Bearden | Fifth | 5 out |
| Monday, June 23 |
| » Defeated White Sox (36-29), 6-4 | Comiskey Park I (2-1) | 30-28 | |
| » Starters: Spec Shea vs Hal Brown | Fifth | 5 out |
| Tuesday, June 24 |
| » Defeated White Sox (36-30), 6-2 | Comiskey Park I (3-1) | 31-28 | Won 2 |
| » Starters: Julio Moreno vs Joe Dobson | Fifth | 5 out |
| Wednesday, June 25 |
| » Defeated White Sox (36-31), 9-6 | Comiskey Park I (4-1) | 32-28 | Won 3 |
| » Starters: Lou Sleater vs Saul Rogovin | Fifth | 4 out |
| Friday, June 27 |
| » Defeated Red Sox (36-30), 5-3 | Fenway Park (3-4) | 33-28 | Won 4 |
| » Starters: Connie Marrero vs Sid Hudson | Fourth | 4 out |
| Saturday, June 28 |
| » Defeated Red Sox (36-31), 5-1 | Fenway Park (4-4) | 34-28 | Won 5 |
| » Starters: Walt Masterson vs Ike Delock | Second | 3 out |
| Sunday, June 29 |
| » Lost to Yankees (38-25), 5-0 | Yankee Stadium (2-2) | 34-29 | |
| » Starters: Bob Porterfield vs Allie Reynolds | Fifth | 5 out |
| » Lost to Yankees (39-25), 3-1 | Yankee Stadium (2-3) | 34-30 | Lost 2 |
| » Starters: Randy Gumpert vs Bill Miller | Fifth | 5 out |
| Monday, June 30 |
| » Defeated Athletics (27-33), 6-2 | Shibe Park (3-1) | 35-30 | |
| » Starters: Spec Shea vs Harry Byrd | Fourth | 4 out |
| Tuesday, July 1 |
| » Defeated Athletics (27-34), 6-5 | Shibe Park (4-1) | 36-30 | Won 2 |
| » Starters: Julio Moreno vs Alex Kellner | Second | 4 out |
| Wednesday, July 2 |
| » Lost to Athletics (28-34), 4-1 | Shibe Park (4-2) | 36-31 | |
| » Starters: Bob Porterfield vs Bobby Shantz | Fifth | 4 out |
| Thursday, July 3 |
| » Lost to Yankees (41-27), 9-6 | Griffith Stadium (13-14) | 36-32 | Lost 2 |
| » Starters: Tom Morgan vs Walt Masterson | Fourth | 4 out |
| » Defeated Yankees (41-28), 6-4 | Griffith Stadium (14-14) | 37-32 | |
| » Starters: Joe Ostrowski vs Lou Sleater | Fourth | 4 out |
| Friday, July 4 |
| » Lost to Yankees (42-28), 9-4 | Griffith Stadium (14-15) | 37-33 | |
| » Starters: Bill Miller vs Randy Gumpert | Fifth | 6 out |
| » Lost to Yankees (43-28), 4-3 | Griffith Stadium (14-16) | 37-34 | Lost 2 |
| » Starters: Bob Kuzava vs Connie Marrero | Fifth | 6 out |
| Saturday, July 5 |
| » Defeated Red Sox (39-35), 4-3 | Griffith Stadium (15-16) | 38-34 | |
| » Starters: Dick Brodowski vs Spec Shea | Fourth | 6 out |
| Sunday, July 6 |
| » Defeated Red Sox (39-36), 5-2 | Griffith Stadium (16-16) | 39-34 | Won 2 |
| » Starters: Mickey McDermott vs Julio Moreno | Fourth | 5½ out |
| Thursday, July 10 |
| » Lost to White Sox (45-34), 2-0 | Griffith Stadium (16-17) | 39-35 | |
| » Starters: Billy Pierce vs Bob Porterfield | Fourth | 7 out |
| » Lost to White Sox (46-34), 4-2 | Griffith Stadium (16-18) | 39-36 | Lost 2 |
| » Starters: Saul Rogovin vs Walt Masterson | Fourth | 7 out |
| Friday, July 11 |
| » Defeated White Sox (46-35), 2-1 | Griffith Stadium (17-18) | 40-36 | |
| » Starters: Joe Dobson vs Spec Shea | Fifth | 6 out |
| Saturday, July 12 |
| » Defeated White Sox (46-36), 2-1 | Griffith Stadium (18-18) | 41-36 | Won 2 |
| » Starters: Chuck Stobbs vs Julio Moreno | Fifth | 6 out |
| Sunday, July 13 |
| » Lost to Indians (45-34), 1-0 | Griffith Stadium (18-19) | 41-37 | |
| » Starters: Mike Garcia vs Connie Marrero | Fifth | 8 out |
| » Lost to Indians (46-34), 2-1 | Griffith Stadium (18-20) | 41-38 | Lost 2 |
| » Starters: Steve Gromek vs Randy Gumpert | Fifth | 8 out |
| Monday, July 14 |
| » Defeated Indians (46-35), 15-4 | Griffith Stadium (19-20) | 42-38 | |
| » Starters: Sam Jones vs Sandy Consuegra | Fifth | 7 out |
| Tuesday, July 15 |
| » Defeated Tigers (26-55), 8-2 | Griffith Stadium (20-20) | 43-38 | Won 2 |
| » Starters: Ted Gray vs Walt Masterson | Fifth | 5½ out |
| » Defeated Tigers (26-56), 9-8 | Griffith Stadium (21-20) | 44-38 | Won 3 |
| » Starters: Ken Johnson vs Bob Porterfield | Fifth | 5½ out |
| Wednesday, July 16 |
| » Lost to Tigers (27-56), 9-0 | Griffith Stadium (21-21) | 44-39 | |
| » Starters: Bill Wight vs Don Johnson | Fifth | 7 out |
| Thursday, July 17 |
| » Defeated Tigers (27-57), 1-0 | Griffith Stadium (22-21) | 45-39 | |
| » Starters: Hal Newhouser vs Spec Shea | Fourth | 6½ out |
| Friday, July 18 |
| » Defeated Browns (35-53), 6-5 | Griffith Stadium (23-21) | 46-39 | Won 2 |
| » Starters: Stubby Overmire vs Randy Gumpert | Fourth | 6½ out |
| Saturday, July 19 |
| » Defeated Browns (35-54), 2-1 | Griffith Stadium (24-21) | 47-39 | Won 3 |
| » Starters: Gene Bearden vs Julio Moreno | Fourth | 6½ out |
| Sunday, July 20 |
| » Defeated Browns (35-55), 7-6 | Griffith Stadium (25-21) | 48-39 | Won 4 |
| » Starters: Duane Pillette vs Connie Marrero | Third | 5 out |
| » Defeated Browns (35-56), 6-3 | Griffith Stadium (26-21) | 49-39 | Won 5 |
| » Starters: Tommy Byrne vs Bob Porterfield | Third | 5 out |
| Tuesday, July 22 |
| » Lost to Tigers (29-59), 1-0 | Tiger Stadium (2-5) | 49-40 | |
| » Starters: Walt Masterson vs Virgil Trucks | Third | 6½ out |
| Wednesday, July 23 |
| » Defeated Tigers (29-60), 5-2 | Tiger Stadium (3-5) | 50-40 | |
| » Starters: Spec Shea vs Hal Newhouser | Third | 5½ out |
| Thursday, July 24 |
| » Lost to Tigers (30-60), 4-2 | Tiger Stadium (3-6) | 50-41 | |
| » Starters: Randy Gumpert vs Bill Wight | Third | 5½ out |
| Friday, July 25 |
| » Lost to Indians (52-42), 4-2 | Cleveland Stadium (4-2) | 50-42 | Lost 2 |
| » Starters: Bob Porterfield vs Early Wynn | Fourth | 5½ out |
| Saturday, July 26 |
| » Defeated Indians (52-43), 11-10 | Cleveland Stadium (5-2) | 51-42 | |
| » Starters: Julio Moreno vs Bob Feller | Third | 4½ out |
| Sunday, July 27 |
| » Lost to Indians (53-43), 3-1 | Cleveland Stadium (5-3) | 51-43 | |
| » Starters: Connie Marrero vs Bob Lemon | Fourth | 5½ out |
| » Lost to Indians (54-43), 3-2 | Cleveland Stadium (5-4) | 51-44 | Lost 2 |
| » Starters: Walt Masterson vs Mike Garcia | Fourth | 5½ out |
| Monday, July 28 |
| » Lost to Browns (40-59), 6-3 | Sportsman's Park III (3-4) | 51-45 | Lost 3 |
| » Starters: Lou Sleater vs Satchel Paige | Fourth | 5½ out |
| Tuesday, July 29 |
| » Lost to Browns (41-59), 7-3 | Sportsman's Park III (3-5) | 51-46 | Lost 4 |
| » Starters: Spec Shea vs Ned Garver | Fourth | 6½ out |
| Wednesday, July 30 |
| » Defeated Browns (41-60), 6-2 | Sportsman's Park III (4-5) | 52-46 | |
| » Starters: Bob Porterfield vs Tommy Byrne | Fourth | 5½ out |
| » Major-league debuts: J.W. Porter (Browns) |
| Thursday, July 31 |
| » Defeated Browns (41-61), 10-5 | Sportsman's Park III (5-5) | 53-46 | Won 2 |
| » Starters: Randy Gumpert vs Bob Cain | Fourth | 5½ out |
| Friday, August 1 |
| » Defeated White Sox (52-51), 3-1 | Comiskey Park I (5-1) | 54-46 | Won 3 |
| » Starters: Walt Masterson vs Joe Dobson | Fourth | 4½ out |
| Saturday, August 2 |
| » Lost to White Sox (53-51), 6-1 | Comiskey Park I (5-2) | 54-47 | |
| » Starters: Julio Moreno vs Chuck Stobbs | Fourth | 4½ out |
| Sunday, August 3 |
| » Tied White Sox, 0-0 | Comiskey Park I (5-2) | 54-47 | |
| » Starters: Connie Marrero vs Billy Pierce | Fourth | 5½ out |
| Monday, August 4 |
| » Lost to Yankees (62-43), 1-0 | Griffith Stadium (26-22) | 54-48 | Lost 2 |
| » Starters: Vic Raschi vs Bob Porterfield | Fourth | 6½ out |
| Tuesday, August 5 |
| » Lost to Yankees (63-43), 3-2 | Griffith Stadium (26-23) | 54-49 | Lost 3 |
| » Starters: Allie Reynolds vs Spec Shea | Fourth | 7½ out |
| Wednesday, August 6 |
| » Defeated Yankees (63-44), 6-4 | Griffith Stadium (27-23) | 55-49 | |
| » Starters: Harry Schaeffer vs Walt Masterson | Fourth | 6½ out |
| Thursday, August 7 |
| » Defeated Yankees (63-45), 4-2 | Griffith Stadium (28-23) | 56-49 | Won 2 |
| » Starters: Jim McDonald vs Julio Moreno | Fourth | 6½ out |
| » Lost to Yankees (64-45), 7-1 | Griffith Stadium (28-24) | 56-50 | |
| » Starters: Bob Kuzava vs Don Johnson | Fourth | 6½ out |
| Sunday, August 10 |
| » Defeated Athletics (52-50), 4-2 | Griffith Stadium (29-24) | 57-50 | |
| » Starters: Bobby Shantz vs Connie Marrero | Fourth | 6 out |
| » Lost to Athletics (53-50), 4-2 | Griffith Stadium (29-25) | 57-51 | |
| » Starters: Harry Byrd vs Spec Shea | Fourth | 6 out |
| Monday, August 11 |
| » Defeated Athletics (53-51), 6-5 | Griffith Stadium (30-25) | 58-51 | |
| » Starters: Sam Zoldak vs Walt Masterson | Fourth | 6½ out |
| » Lost to Athletics (54-51), 2-1 | Griffith Stadium (30-26) | 58-52 | |
| » Starters: Alex Kellner vs Randy Gumpert | Fourth | 6½ out |
| Wednesday, August 13 |
| » Defeated Yankees (65-47), 12-4 | Yankee Stadium (3-3) | 59-52 | |
| » Starters: Bob Porterfield vs Vic Raschi | Fourth | 6½ out |
| » Lost to Yankees (66-47), 10-9 | Yankee Stadium (3-4) | 59-53 | |
| » Starters: Julio Moreno vs Bob Kuzava | Fourth | 6½ out |
| Thursday, August 14 |
| » Lost to Yankees (67-47), 7-2 | Yankee Stadium (3-5) | 59-54 | Lost 2 |
| » Starters: Joe Haynes vs Johnny Schmitz | Fifth | 7½ out |
| Friday, August 15 |
| » Lost to Athletics (56-54), 11-7 | Shibe Park (4-3) | 59-55 | Lost 3 |
| » Starters: Spec Shea vs Bobby Shantz | Fifth | 7½ out |
| Saturday, August 16 |
| » Defeated Athletics (56-55), 10-3 | Shibe Park (5-3) | 60-55 | |
| » Starters: Walt Masterson vs Alex Kellner | Fourth | 7½ out |
| Sunday, August 17 |
| » Defeated Athletics (56-56), 7-2 | Shibe Park (6-3) | 61-55 | Won 2 |
| » Starters: Bob Porterfield vs Sam Zoldak | Fourth | 8 out |
| » Lost to Athletics (57-56), 12-5 | Shibe Park (6-4) | 61-56 | |
| » Starters: Randy Gumpert vs Carl Scheib | Fourth | 8 out |
| Tuesday, August 19 |
| » Defeated Browns (50-70), 2-1 | Griffith Stadium (31-26) | 62-56 | |
| » Starters: Duane Pillette vs Connie Marrero | Fourth | 7½ out |
| Thursday, August 21 |
| » Defeated Browns (50-71), 3-2 | Griffith Stadium (32-26) | 63-56 | Won 2 |
| » Starters: Tommy Byrne vs Spec Shea | Fourth | 6½ out |
| » Lost to Browns (51-71), 8-1 | Griffith Stadium (32-27) | 63-57 | |
| » Starters: Bob Cain vs Walt Masterson | Fourth | 6½ out |
| Former Senator Jack Ryan dies in Boston, MA at the age of 84. |
| Friday, August 22 |
| » Lost to Tigers (40-80), 2-0 | Griffith Stadium (32-28) | 63-58 | Lost 2 |
| » Starters: Ted Gray vs Bob Porterfield | Sixth | 6½ out |
| Saturday, August 23 |
| » Lost to Tigers (41-80), 6-3 | Griffith Stadium (32-29) | 63-59 | Lost 3 |
| » Starters: Hal Newhouser vs Julio Moreno | Sixth | 7½ out |
| Sunday, August 24 |
| » Defeated Indians (69-53), 9-8 | Griffith Stadium (33-29) | 64-59 | |
| » Starters: Bob Feller vs Walt Masterson | Sixth | 7½ out |
| Monday, August 25 |
| » Lost to Indians (70-53), 7-2 | Griffith Stadium (33-30) | 64-60 | |
| » Starters: Bob Lemon vs Connie Marrero | Sixth | 7½ out |
| Tuesday, August 26 |
| » Defeated White Sox (65-61), 1-0 | Griffith Stadium (34-30) | 65-60 | |
| » Starters: Billy Pierce vs Bob Porterfield | Fourth | 7½ out |
| Wednesday, August 27 |
| » Lost to White Sox (66-61), 4-1 | Griffith Stadium (34-31) | 65-61 | |
| » Starters: Chuck Stobbs vs Julio Moreno | Sixth | 8½ out |
| Friday, August 29 |
| » Defeated Yankees (74-54), 3-2 | Yankee Stadium (4-5) | 66-61 | |
| » Starters: Walt Masterson vs Vic Raschi | Fifth | 7½ out |
| Saturday, August 30 |
| » Lost to Yankees (75-54), 6-4 | Yankee Stadium (4-6) | 66-62 | |
| » Starters: Randy Gumpert vs Allie Reynolds | Sixth | 8½ out |
| Sunday, August 31 |
| » Lost to Yankees (76-54), 6-1 | Yankee Stadium (4-7) | 66-63 | Lost 2 |
| » Starters: Bob Porterfield vs Ed Lopat | Sixth | 9½ out |
| Monday, September 1 |
| » Lost to Athletics (69-60), 9-8 | Griffith Stadium (34-32) | 66-64 | Lost 3 |
| » Starters: Alex Kellner vs Connie Marrero | Sixth | 10 out |
| » Defeated Athletics (69-61), 4-2 | Griffith Stadium (35-32) | 67-64 | |
| » Starters: Carl Scheib vs Julio Moreno | Sixth | 10 out |
| Tuesday, September 2 |
| » Defeated Athletics (69-62), 3-2 | Griffith Stadium (36-32) | 68-64 | Won 2 |
| » Starters: Bobo Newsom vs Walt Masterson | Sixth | 10 out |
| » Defeated Athletics (69-63), 5-0 | Griffith Stadium (37-32) | 69-64 | Won 3 |
| » Starters: Charlie Bishop vs Mike Fornieles | Sixth | 10 out |
| » Major-league debuts: Mike Fornieles (Senators) |
| Wednesday, September 3 |
| » Defeated Red Sox (69-62), 9-2 | Griffith Stadium (38-32) | 70-64 | Won 4 |
| » Starters: Dizzy Trout vs Randy Gumpert | Sixth | 9 out |
| Thursday, September 4 |
| » Defeated Red Sox (69-63), 4-2 | Griffith Stadium (39-32) | 71-64 | Won 5 |
| » Starters: Mickey McDermott vs Bob Porterfield | Third | 9 out |
| Friday, September 5 |
| » Defeated Red Sox (69-64), 2-0 | Griffith Stadium (40-32) | 72-64 | Won 6 |
| » Starters: Ellis Kinder vs Raul Sanchez | Third | 8 out |
| Saturday, September 6 |
| » Lost to Yankees (81-56), 5-2 | Griffith Stadium (40-33) | 72-65 | |
| » Starters: Ray Scarborough vs Connie Marrero | Third | 9 out |
| Sunday, September 7 |
| » Lost to Yankees (82-56), 5-1 | Griffith Stadium (40-34) | 72-66 | Lost 2 |
| » Starters: Ed Lopat vs Walt Masterson | Fourth | 10 out |
| Tuesday, September 9 |
| » Lost to White Sox (72-65), 3-2 | Comiskey Park I (5-3) | 72-67 | Lost 3 |
| » Starters: Bob Porterfield vs Saul Rogovin | Fifth | 10½ out |
| » Lost to White Sox (73-65), 3-2 | Comiskey Park I (5-4) | 72-68 | Lost 4 |
| » Starters: Mike Fornieles vs Harry Dorish | Fifth | 10½ out |
| Wednesday, September 10 |
| » Lost to White Sox (74-65), 6-3 | Comiskey Park I (5-5) | 72-69 | Lost 5 |
| » Starters: Raul Sanchez vs Billy Pierce | Fifth | 11½ out |
| Thursday, September 11 |
| » Defeated White Sox (74-66), 4-1 | Comiskey Park I (6-5) | 73-69 | |
| » Starters: Walt Masterson vs Joe Dobson | Fifth | 11 out |
| Friday, September 12 |
| » Lost to Browns (58-83), 5-4 | Sportsman's Park III (5-6) | 73-70 | |
| » Starters: Julio Moreno vs Bob Cain | Fifth | 12 out |
| Saturday, September 13 |
| » Major-league debuts: Bud Black (Tigers) |
| Sunday, September 14 |
| » Defeated Tigers (48-94), 6-2 | Tiger Stadium (4-6) | 74-70 | |
| » Starters: Connie Marrero vs Ted Gray | Fifth | 12½ out |
| Monday, September 15 |
| » Lost to Tigers (49-94), 5-4 | Tiger Stadium (4-7) | 74-71 | |
| » Starters: Spec Shea vs Bill Wight | Fifth | 13 out |
| Tuesday, September 16 |
| » Lost to Indians (85-60), 4-3 | Cleveland Stadium (5-5) | 74-72 | Lost 2 |
| » Starters: Bob Porterfield vs Mike Garcia | Sixth | 14 out |
| Wednesday, September 17 |
| » Lost to Indians (86-60), 6-1 | Cleveland Stadium (5-6) | 74-73 | Lost 3 |
| » Starters: Walt Masterson vs Bob Lemon | Sixth | 15 out |
| Friday, September 19 |
| » Defeated Red Sox (74-72), 5-3 | Griffith Stadium (41-34) | 75-73 | |
| » Starters: Sid Hudson vs Julio Moreno | Fifth | 14 out |
| Saturday, September 20 |
| » Defeated Red Sox (74-73), 10-6 | Griffith Stadium (42-34) | 76-73 | Won 2 |
| » Starters: Mel Parnell vs Spec Shea | Fifth | 14 out |
| Sunday, September 21 |
| » Lost to Red Sox (75-73), 7-3 | Griffith Stadium (42-35) | 76-74 | |
| » Starters: Dizzy Trout vs Connie Marrero | Fifth | 15 out |
| Tuesday, September 23 |
| » Lost to Athletics (78-73), 4-3 | Shibe Park (6-5) | 76-75 | Lost 2 |
| » Starters: Walt Masterson vs Bobby Shantz | Sixth | 15½ out |
| Friday, September 26 |
| » Lost to Red Sox (76-76), 3-1 | Fenway Park (4-5) | 76-76 | Lost 3 |
| » Starters: Spec Shea vs Hersh Freeman | Fifth | 18 out |
| Saturday, September 27 |
| » Defeated Red Sox (76-77), 3-2 | Fenway Park (5-5) | 77-76 | |
| » Starters: Bob Porterfield vs Dizzy Trout | Fifth | 18 out |
| Sunday, September 28 |
| » Defeated Red Sox (76-78), 5-4 | Fenway Park (6-5) | 78-76 | Won 2 |
| » Starters: Walt Masterson vs Mickey McDermott | Fifth | 17 out |
| Tuesday, September 30 |
| Former Senator Jerry Freeman dies in Los Angeles, CA at the age of 73. |
Game information provided by Retrosheet (www.retrosheet.org) |