| Tuesday, February 26 |
| Future Indian Dennis Kinney is born in Toledo, OH. |
| Thursday, March 20 |
| Former Indian Harry Bay dies in Peoria, IL at the age of 75. |
| Tuesday, April 15 |
| » Defeated White Sox (0-1), 3-2 | Comiskey Park I (1-0) | 1-0 | |
| » Starters: Early Wynn vs Billy Pierce | First | -- |
| » Major-league debuts: George Wilson (White Sox) Jim Fridley (Indians) |
| Wednesday, April 16 |
| » Defeated White Sox (0-2), 1-0 | Comiskey Park I (2-0) | 2-0 | Won 2 |
| » Starters: Bob Lemon vs Joe Dobson | First | -- |
| Thursday, April 17 |
| » Defeated White Sox (0-3), 5-3 | Comiskey Park I (3-0) | 3-0 | Won 3 |
| » Starters: Mike Garcia vs Marv Grissom | First | -- |
| Friday, April 18 |
| » Defeated Tigers (0-4), 5-0 | Cleveland Stadium (1-0) | 4-0 | Won 4 |
| » Starters: Ted Gray vs Bob Feller | First | -- |
| » Major-league debuts: Billy Hoeft (Tigers) |
| Saturday, April 19 |
| » Defeated Tigers (0-5), 7-5 | Cleveland Stadium (2-0) | 5-0 | Won 5 |
| » Starters: Virgil Trucks vs Early Wynn | First | -- |
| Sunday, April 20 |
| » Defeated Tigers (0-6), 3-2 | Cleveland Stadium (3-0) | 6-0 | Won 6 |
| » Starters: Art Houtteman vs Bob Lemon | First | -- |
| » Defeated Tigers (0-7), 7-2 | Cleveland Stadium (4-0) | 7-0 | Won 7 |
| » Starters: Dizzy Trout vs Steve Gromek | First | -- |
| Monday, April 21 |
| » Major-league debuts: Ron Kline and Lee Walls (Pirates) |
| Tuesday, April 22 |
| » Lost to Browns (6-2), 8-3 | Sportsman's Park III (0-1) | 7-1 | |
| » Starters: Mike Garcia vs Tommy Byrne | First | -- |
| Wednesday, April 23 |
| » Lost to Browns (7-2), 1-0 | Sportsman's Park III (0-2) | 7-2 | Lost 2 |
| » Starters: Bob Feller vs Bob Cain | Second | ½ out |
| Friday, April 25 |
| » Defeated White Sox (3-6), 5-4 | Cleveland Stadium (5-0) | 8-2 | |
| » Starters: Billy Pierce vs Early Wynn | Second | ½ out |
| Saturday, April 26 |
| » Lost to Tigers (1-8), 13-0 | Tiger Stadium (0-1) | 8-3 | |
| » Starters: Bob Lemon vs Art Houtteman | Second | 1 out |
| Sunday, April 27 |
| » Lost to Tigers (2-8), 1-0 | Tiger Stadium (0-2) | 8-4 | Lost 2 |
| » Starters: Mike Garcia vs Ted Gray | Second | 1½ out |
| Tuesday, April 29 |
| » Defeated Athletics (1-8), 21-9 | Shibe Park (1-0) | 9-4 | |
| » Starters: Bob Feller vs Alex Kellner | Second | 1 out |
| Future Indian Ron Washington is born in New Orleans, LA. |
| Wednesday, April 30 |
| » Lost to Athletics (2-8), 3-1 | Shibe Park (1-1) | 9-5 | |
| » Starters: Early Wynn vs Bobby Shantz | Second | 2 out |
| Thursday, May 1 |
| » Lost to Senators (5-6), 2-1 | Griffith Stadium (0-1) | 9-6 | Lost 2 |
| » Starters: Bob Lemon vs Sid Hudson | Second | 2 out |
| Friday, May 2 |
| » Defeated Senators (5-7), 6-2 | Griffith Stadium (1-1) | 10-6 | |
| » Starters: Mike Garcia vs Julio Moreno | Second | 2 out |
| Saturday, May 3 |
| » Lost to Senators (6-7), 7-6 | Griffith Stadium (1-2) | 10-7 | |
| » Starters: Bob Feller vs Don Johnson | Second | 3 out |
| Sunday, May 4 |
| » Defeated Red Sox (12-4), 9-6 | Fenway Park (1-0) | 11-7 | |
| » Starters: Early Wynn vs Mickey McDermott | Second | 2 out |
| Monday, May 5 |
| » Defeated Red Sox (12-5), 4-2 | Fenway Park (2-0) | 12-7 | Won 2 |
| » Starters: Bob Lemon vs Mel Parnell | Second | 1 out |
| Tuesday, May 6 |
| » Defeated Yankees (8-9), 1-0 | Yankee Stadium (1-0) | 13-7 | Won 3 |
| » Starters: Steve Gromek vs Allie Reynolds | Second | 1 out |
| Wednesday, May 7 |
| » Defeated Yankees (8-10), 7-2 | Yankee Stadium (2-0) | 14-7 | Won 4 |
| » Starters: Mike Garcia vs Vic Raschi | Second | 1 out |
| Thursday, May 8 |
| » Defeated Yankees (8-11), 12-5 | Yankee Stadium (3-0) | 15-7 | Won 5 |
| » Starters: Bob Feller vs Ed Lopat | Second | 1 out |
| Saturday, May 10 |
| » Lost to Browns (12-12), 6-4 | Cleveland Stadium (5-1) | 15-8 | |
| » Starters: Tommy Byrne vs Early Wynn | First | -- |
| Sunday, May 11 |
| » Defeated Browns (12-13), 1-0 | Cleveland Stadium (6-1) | 16-8 | |
| » Starters: Ned Garver vs Bob Lemon | First | -- |
| » Defeated Browns (12-14), 3-1 | Cleveland Stadium (7-1) | 17-8 | Won 2 |
| » Starters: Bob Cain vs Mike Garcia | First | -- |
| Tuesday, May 13 |
| » Defeated Yankees (11-12), 10-6 | Cleveland Stadium (8-1) | 18-8 | Won 3 |
| » Starters: Bill Miller vs Steve Gromek | First | -- |
| Wednesday, May 14 |
| » Lost to Yankees (12-12), 5-3 | Cleveland Stadium (8-2) | 18-9 | |
| » Starters: Johnny Sain vs Bob Feller | First | -- |
| Thursday, May 15 |
| Future Indian Rick Waits is born in Atlanta, GA. |
| Friday, May 16 |
| » Lost to Senators (15-10), 2-0 | Cleveland Stadium (8-3) | 18-10 | Lost 2 |
| » Starters: Spec Shea vs Early Wynn | First | -- |
| Saturday, May 17 |
| » Defeated Senators (15-11), 9-2 | Cleveland Stadium (9-3) | 19-10 | |
| » Starters: Julio Moreno vs Bob Lemon | First | -- |
| Sunday, May 18 |
| » Lost to Athletics (11-14), 2-0 | Cleveland Stadium (9-4) | 19-11 | |
| » Starters: Bobby Shantz vs Bob Feller | First | -- |
| » Defeated Athletics (11-15), 6-0 | Cleveland Stadium (10-4) | 20-11 | |
| » Starters: Sam Zoldak vs Mike Garcia | First | -- |
| Wednesday, May 21 |
| » Defeated Red Sox (17-14), 5-1 | Cleveland Stadium (11-4) | 21-11 | Won 2 |
| » Starters: Ray Scarborough vs Early Wynn | First | -- |
| Thursday, May 22 |
| » Lost to Red Sox (18-14), 3-2 | Cleveland Stadium (11-5) | 21-12 | |
| » Starters: Mickey McDermott vs Bob Lemon | First | -- |
| Friday, May 23 |
| » Defeated Browns (17-20), 6-3 | Sportsman's Park III (1-2) | 22-12 | |
| » Starters: Mike Garcia vs Ned Garver | First | -- |
| Saturday, May 24 |
| » Defeated Browns (17-21), 5-3 | Sportsman's Park III (2-2) | 23-12 | Won 2 |
| » Starters: Bob Feller vs Bob Cain | First | -- |
| Sunday, May 25 |
| » Lost to Browns (18-21), 7-5 | Sportsman's Park III (2-3) | 23-13 | |
| » Starters: Steve Gromek vs Duane Pillette | First | -- |
| » Defeated Browns (18-22), 6-2 | Sportsman's Park III (3-3) | 24-13 | |
| » Starters: Sam Jones vs Tommy Byrne | First | -- |
| Tuesday, May 27 |
| » Lost to Tigers (10-23), 6-4 | Cleveland Stadium (11-6) | 24-14 | |
| » Starters: Marlin Stuart vs Bob Lemon | First | -- |
| Wednesday, May 28 |
| » Lost to Tigers (11-23), 6-2 | Tiger Stadium (0-3) | 24-15 | Lost 2 |
| » Starters: Mike Garcia vs Ted Gray | First | -- |
| Thursday, May 29 |
| » Defeated Tigers (11-24), 11-4 | Tiger Stadium (1-3) | 25-15 | |
| » Starters: Bob Feller vs Art Houtteman | First | -- |
| Friday, May 30 |
| » Lost to White Sox (21-19), 7-2 | Cleveland Stadium (11-7) | 25-16 | |
| » Starters: Billy Pierce vs Early Wynn | First | -- |
| » Lost to White Sox (22-19), 3-1 | Cleveland Stadium (11-8) | 25-17 | Lost 2 |
| » Starters: Joe Dobson vs Sam Jones | First | -- |
| Monday, June 2 |
| » Lost to Yankees (19-17), 2-0 | Yankee Stadium (3-1) | 25-18 | Lost 3 |
| » Starters: Bob Lemon vs Allie Reynolds | Second | 1 out |
| Tuesday, June 3 |
| » Defeated Red Sox (24-18), 6-0 | Fenway Park (3-0) | 26-18 | |
| » Starters: Mike Garcia vs Mickey McDermott | First | -- |
| Wednesday, June 4 |
| » Lost to Red Sox (25-18), 13-11 | Fenway Park (3-1) | 26-19 | |
| » Starters: Bob Feller vs Mel Parnell | Second | 1 out |
| Thursday, June 5 |
| » Defeated Red Sox (25-19), 5-0 | Fenway Park (4-1) | 27-19 | |
| » Starters: Early Wynn vs Ellis Kinder | First | -- |
| Friday, June 6 |
| » Defeated Athletics (18-21), 11-4 | Shibe Park (2-1) | 28-19 | Won 2 |
| » Starters: Bob Lemon vs Harry Byrd | First | -- |
| Saturday, June 7 |
| » Defeated Athletics (18-22), 14-0 | Shibe Park (3-1) | 29-19 | Won 3 |
| » Starters: Mike Garcia vs Alex Kellner | First | -- |
| Sunday, June 8 |
| » Lost to Athletics (19-22), 12-4 | Shibe Park (3-2) | 29-20 | |
| » Starters: Sam Jones vs Bobby Shantz | Third | 1 out |
| » Lost to Athletics (20-22), 11-3 | Shibe Park (3-3) | 29-21 | Lost 2 |
| » Starters: Bob Feller vs Alex Kellner | Third | 1 out |
| Tuesday, June 10 |
| » Defeated Senators (23-23), 4-3 | Griffith Stadium (2-2) | 30-21 | |
| » Starters: Early Wynn vs Connie Marrero | Second | 3½ out |
| Wednesday, June 11 |
| » Lost to Senators (24-23), 1-0 | Griffith Stadium (2-3) | 30-22 | |
| » Starters: Bob Lemon vs Bob Porterfield | Third | 3½ out |
| Thursday, June 12 |
| » Defeated Senators (24-24), 7-4 | Griffith Stadium (3-3) | 31-22 | |
| » Starters: Bob Feller vs Spec Shea | Third | 3½ out |
| Friday, June 13 |
| » Defeated Yankees (28-19), 7-1 | Cleveland Stadium (12-8) | 32-22 | Won 2 |
| » Starters: Allie Reynolds vs Mike Garcia | Third | 1 out |
| Saturday, June 14 |
| » Lost to Yankees (29-19), 11-0 | Cleveland Stadium (12-9) | 32-23 | |
| » Starters: Vic Raschi vs Early Wynn | Third | 3½ out |
| Sunday, June 15 |
| » Lost to Yankees (30-19), 8-2 | Cleveland Stadium (12-10) | 32-24 | Lost 2 |
| » Starters: Ed Lopat vs Bob Lemon | Third | 3½ out |
| » Lost to Yankees (31-19), 4-3 | Cleveland Stadium (12-11) | 32-25 | Lost 3 |
| » Starters: Bob Kuzava vs Steve Gromek | Third | 3½ out |
| Tuesday, June 17 |
| » Lost to Senators (26-26), 4-3 | Cleveland Stadium (12-12) | 32-26 | Lost 4 |
| » Starters: Bob Porterfield vs Bob Feller | Third | 3½ out |
| Wednesday, June 18 |
| » Lost to Senators (27-26), 3-2 | Cleveland Stadium (12-13) | 32-27 | Lost 5 |
| » Starters: Spec Shea vs Mike Garcia | Fourth | 3½ out |
| Thursday, June 19 |
| » Lost to Senators (28-26), 6-3 | Cleveland Stadium (12-14) | 32-28 | Lost 6 |
| » Starters: Connie Marrero vs Early Wynn | Fourth | 4½ out |
| Friday, June 20 |
| » Defeated Red Sox (33-26), 9-2 | Cleveland Stadium (13-14) | 33-28 | |
| » Starters: Mel Parnell vs Bob Lemon | Fourth | 3½ out |
| Saturday, June 21 |
| » Lost to Red Sox (34-26), 3-1 | Cleveland Stadium (13-15) | 33-29 | |
| » Starters: Sid Hudson vs Bob Feller | Fourth | 3½ out |
| Sunday, June 22 |
| » Defeated Red Sox (34-27), 7-0 | Cleveland Stadium (14-15) | 34-29 | |
| » Starters: Willard Nixon vs Steve Gromek | Fourth | 3½ out |
| » Defeated Red Sox (34-28), 5-4 | Cleveland Stadium (15-15) | 35-29 | Won 2 |
| » Starters: Dizzy Trout vs Mike Garcia | Fourth | 3½ out |
| Tuesday, June 24 |
| » Defeated Athletics (25-31), 2-1 | Cleveland Stadium (16-15) | 36-29 | Won 3 |
| » Starters: Bobby Shantz vs Early Wynn | Second | 3 out |
| Wednesday, June 25 |
| » Lost to Athletics (26-31), 11-9 | Cleveland Stadium (16-16) | 36-30 | |
| » Starters: Alex Kellner vs Bob Lemon | Third | 3 out |
| Friday, June 27 |
| » Lost to White Sox (37-31), 5-1 | Comiskey Park I (3-1) | 36-31 | Lost 2 |
| » Starters: Bob Feller vs Billy Pierce | Fifth | 4 out |
| Saturday, June 28 |
| » Defeated White Sox (37-32), 5-1 | Comiskey Park I (4-1) | 37-31 | |
| » Starters: Mike Garcia vs Chuck Stobbs | Third | 3 out |
| Sunday, June 29 |
| » Lost to White Sox (38-32), 4-2 | Comiskey Park I (4-2) | 37-32 | |
| » Starters: Early Wynn vs Saul Rogovin | Fourth | 4½ out |
| » Tied White Sox, 7-7 | Comiskey Park I (4-2) | 37-32 | |
| » Starters: Bob Lemon vs Marv Grissom | Fourth | 4½ out |
| Tuesday, July 1 |
| » Defeated Browns (32-39), 4-3 | Cleveland Stadium (17-16) | 38-32 | |
| » Starters: Ned Garver vs Bob Feller | Third | 4 out |
| » Major-league debuts: Dave Pope (Indians) |
| Wednesday, July 2 |
| » Defeated Browns (32-40), 3-2 | Cleveland Stadium (18-16) | 39-32 | Won 2 |
| » Starters: Gene Bearden vs Mike Garcia | Second | 3 out |
| Friday, July 4 |
| » Defeated Tigers (23-48), 11-0 | Tiger Stadium (2-3) | 40-32 | Won 3 |
| » Starters: Early Wynn vs Ted Gray | Third | 3 out |
| » Defeated Tigers (23-49), 10-1 | Tiger Stadium (3-3) | 41-32 | Won 4 |
| » Starters: Bob Lemon vs Virgil Trucks | Third | 3 out |
| Saturday, July 5 |
| » Defeated White Sox (43-34), 3-2 | Cleveland Stadium (19-16) | 42-32 | Won 5 |
| » Starters: Joe Dobson vs Bob Feller | Second | 3 out |
| Sunday, July 6 |
| » Lost to White Sox (44-34), 3-2 | Cleveland Stadium (19-17) | 42-33 | |
| » Starters: Billy Pierce vs Mike Garcia | Third | 3½ out |
| Thursday, July 10 |
| » Lost to Athletics (32-37), 11-1 | Shibe Park (3-4) | 42-34 | Lost 2 |
| » Starters: Early Wynn vs Alex Kellner | Third | 4½ out |
| Friday, July 11 |
| » Defeated Athletics (32-38), 8-7 | Shibe Park (4-4) | 43-34 | |
| » Starters: Bob Feller vs Harry Byrd | Third | 3½ out |
| Saturday, July 12 |
| » Defeated Athletics (32-39), 5-1 | Shibe Park (5-4) | 44-34 | Won 2 |
| » Starters: Bob Lemon vs Sam Zoldak | Second | 3½ out |
| Sunday, July 13 |
| » Defeated Senators (41-37), 1-0 | Griffith Stadium (4-3) | 45-34 | Won 3 |
| » Starters: Mike Garcia vs Connie Marrero | Second | 3½ out |
| » Defeated Senators (41-38), 2-1 | Griffith Stadium (5-3) | 46-34 | Won 4 |
| » Starters: Steve Gromek vs Randy Gumpert | Second | 3½ out |
| Monday, July 14 |
| » Lost to Senators (42-38), 15-4 | Griffith Stadium (5-4) | 46-35 | |
| » Starters: Sam Jones vs Sandy Consuegra | Second | 3½ out |
| Tuesday, July 15 |
| » Defeated Yankees (49-32), 7-3 | Yankee Stadium (4-1) | 47-35 | |
| » Starters: Early Wynn vs Bob Kuzava | Second | 2½ out |
| Wednesday, July 16 |
| » Lost to Yankees (50-32), 8-7 | Yankee Stadium (4-2) | 47-36 | |
| » Starters: Bob Lemon vs Johnny Sain | Second | 4½ out |
| » Lost to Yankees (51-32), 7-4 | Yankee Stadium (4-3) | 47-37 | Lost 2 |
| » Starters: Bob Feller vs Bill Miller | Second | 4½ out |
| » Major-league debuts: Tom Gorman and Kal Segrist (Yankees) |
| Thursday, July 17 |
| » Defeated Yankees (51-33), 11-6 | Yankee Stadium (5-3) | 48-37 | |
| » Starters: Steve Gromek vs Allie Reynolds | Third | 4½ out |
| » Lost to Yankees (52-33), 5-4 | Yankee Stadium (5-4) | 48-38 | |
| » Starters: Mike Garcia vs Vic Raschi | Third | 4½ out |
| Friday, July 18 |
| » Lost to Red Sox (48-37), 9-2 | Fenway Park (4-2) | 48-39 | Lost 2 |
| » Starters: Lou Brissie vs Mickey McDermott | Third | 5½ out |
| Saturday, July 19 |
| » Defeated Red Sox (48-38), 4-0 | Fenway Park (5-2) | 49-39 | |
| » Starters: Bob Lemon vs Sid Hudson | Third | 5½ out |
| Sunday, July 20 |
| » Lost to Red Sox (49-38), 8-7 | Fenway Park (5-3) | 49-40 | |
| » Starters: Early Wynn vs Dick Brodowski | Fourth | 5½ out |
| Tuesday, July 22 |
| » Lost to Yankees (55-34), 7-3 | Cleveland Stadium (19-18) | 49-41 | Lost 2 |
| » Starters: Vic Raschi vs Bob Feller | Fourth | 7½ out |
| » Lost to Yankees (56-34), 8-1 | Cleveland Stadium (19-19) | 49-42 | Lost 3 |
| » Starters: Allie Reynolds vs Steve Gromek | Fourth | 7½ out |
| Wednesday, July 23 |
| » Defeated Yankees (56-35), 7-3 | Cleveland Stadium (20-19) | 50-42 | |
| » Starters: Tom Gorman vs Bob Lemon | Fourth | 6½ out |
| Thursday, July 24 |
| » Defeated Yankees (56-36), 4-2 | Cleveland Stadium (21-19) | 51-42 | Won 2 |
| » Starters: Tom Morgan vs Mike Garcia | Fourth | 5½ out |
| Friday, July 25 |
| » Defeated Senators (50-42), 4-2 | Cleveland Stadium (22-19) | 52-42 | Won 3 |
| » Starters: Bob Porterfield vs Early Wynn | Third | 4½ out |
| Saturday, July 26 |
| » Lost to Senators (51-42), 11-10 | Cleveland Stadium (22-20) | 52-43 | |
| » Starters: Julio Moreno vs Bob Feller | Fourth | 4½ out |
| Sunday, July 27 |
| » Defeated Senators (51-43), 3-1 | Cleveland Stadium (23-20) | 53-43 | |
| » Starters: Connie Marrero vs Bob Lemon | Second | 3½ out |
| » Defeated Senators (51-44), 3-2 | Cleveland Stadium (24-20) | 54-43 | Won 2 |
| » Starters: Walt Masterson vs Mike Garcia | Second | 3½ out |
| Tuesday, July 29 |
| » Defeated Red Sox (52-43), 4-1 | Cleveland Stadium (25-20) | 55-43 | Won 3 |
| » Starters: Sid Hudson vs Early Wynn | Second | 3 out |
| Wednesday, July 30 |
| » Lost to Red Sox (53-43), 5-4 | Cleveland Stadium (25-21) | 55-44 | |
| » Starters: Dick Brodowski vs Bob Feller | Second | 3 out |
| Thursday, July 31 |
| » Defeated Red Sox (53-44), 8-2 | Cleveland Stadium (26-21) | 56-44 | |
| » Starters: Ralph Brickner vs Bob Lemon | Second | 3 out |
| Friday, August 1 |
| » Defeated Athletics (48-47), 6-5 | Cleveland Stadium (27-21) | 57-44 | Won 2 |
| » Starters: Sam Zoldak vs Mike Garcia | Second | 2 out |
| Saturday, August 2 |
| » Lost to Athletics (49-47), 6-4 | Cleveland Stadium (27-22) | 57-45 | |
| » Starters: Harry Byrd vs Early Wynn | Second | 2 out |
| Sunday, August 3 |
| » Defeated Athletics (49-48), 4-1 | Cleveland Stadium (28-22) | 58-45 | |
| » Starters: Alex Kellner vs Bob Feller | Second | 3 out |
| » Lost to Athletics (50-48), 9-2 | Cleveland Stadium (28-23) | 58-46 | |
| » Starters: Carl Scheib vs Steve Gromek | Second | 3 out |
| Tuesday, August 5 |
| » Defeated White Sox (53-52), 6-0 | Comiskey Park I (5-2) | 59-46 | |
| » Starters: Bob Lemon vs Lou Kretlow | Second | 4 out |
| » Lost to White Sox (54-52), 6-3 | Comiskey Park I (5-3) | 59-47 | |
| » Starters: Mike Garcia vs Saul Rogovin | Second | 4 out |
| Wednesday, August 6 |
| » Defeated White Sox (54-53), 7-1 | Comiskey Park I (6-3) | 60-47 | |
| » Starters: Early Wynn vs Bill Kennedy | Second | 3 out |
| Friday, August 8 |
| » Defeated Browns (46-64), 10-9 | Sportsman's Park III (4-3) | 61-47 | Won 2 |
| » Starters: Bob Feller vs Duane Pillette | Second | 2½ out |
| Saturday, August 9 |
| » Defeated Browns (46-65), 7-5 | Sportsman's Park III (5-3) | 62-47 | Won 3 |
| » Starters: Mike Garcia vs Tommy Byrne | Second | 1½ out |
| Sunday, August 10 |
| » Lost to Browns (47-65), 6-3 | Sportsman's Park III (5-4) | 62-48 | |
| » Starters: Bob Lemon vs Bob Cain | Second | 2 out |
| Wednesday, August 13 |
| » Lost to Browns (49-65), 5-2 | Cleveland Stadium (28-24) | 62-49 | Lost 2 |
| » Starters: Duane Pillette vs Bob Feller | Second | 2½ out |
| » Defeated Browns (49-66), 9-1 | Cleveland Stadium (29-24) | 63-49 | |
| » Starters: Cliff Fannin vs Early Wynn | Second | 2½ out |
| Friday, August 15 |
| » Defeated Browns (49-67), 7-6 | Cleveland Stadium (30-24) | 64-49 | Won 2 |
| » Starters: Tommy Byrne vs Mike Garcia | Second | 2 out |
| Saturday, August 16 |
| » Defeated White Sox (60-56), 4-3 | Cleveland Stadium (31-24) | 65-49 | Won 3 |
| » Starters: Billy Pierce vs Bob Lemon | Second | 2 out |
| Sunday, August 17 |
| » Defeated White Sox (60-57), 6-2 | Cleveland Stadium (32-24) | 66-49 | Won 4 |
| » Starters: Lou Kretlow vs Bob Feller | Second | 1½ out |
| » Defeated White Sox (60-58), 2-1 | Cleveland Stadium (33-24) | 67-49 | Won 5 |
| » Starters: Chuck Stobbs vs Mike Garcia | Second | 1½ out |
| Tuesday, August 19 |
| » Lost to Red Sox (62-52), 6-5 | Fenway Park (5-4) | 67-50 | |
| » Starters: Early Wynn vs Dick Brodowski | Second | 2 out |
| Wednesday, August 20 |
| » Defeated Red Sox (62-53), 18-8 | Fenway Park (6-4) | 68-50 | |
| » Starters: Bob Lemon vs Mickey McDermott | Second | 1 out |
| Thursday, August 21 |
| » Lost to Red Sox (63-53), 4-1 | Fenway Park (6-5) | 68-51 | |
| » Starters: Steve Gromek vs Sid Hudson | Second | 1 out |
| Friday, August 22 |
| » Defeated Yankees (70-52), 6-4 | Yankee Stadium (6-4) | 69-51 | |
| » Starters: Mike Garcia vs Allie Reynolds | First | -- |
| Saturday, August 23 |
| » Lost to Yankees (71-52), 1-0 | Yankee Stadium (6-5) | 69-52 | |
| » Starters: Early Wynn vs Vic Raschi | Second | 1 out |
| Sunday, August 24 |
| » Lost to Senators (64-59), 9-8 | Griffith Stadium (5-5) | 69-53 | Lost 2 |
| » Starters: Bob Feller vs Walt Masterson | Second | 2 out |
| Monday, August 25 |
| » Defeated Senators (64-60), 7-2 | Griffith Stadium (6-5) | 70-53 | |
| » Starters: Bob Lemon vs Connie Marrero | Second | 1 out |
| Tuesday, August 26 |
| » Defeated Athletics (63-59), 6-3 | Shibe Park (6-4) | 71-53 | Won 2 |
| » Starters: Bob Feller vs Bobby Shantz | Second | 1 out |
| Wednesday, August 27 |
| » Lost to Athletics (64-59), 6-5 | Shibe Park (6-5) | 71-54 | |
| » Starters: Mike Garcia vs Alex Kellner | Second | 2 out |
| Thursday, August 28 |
| » Defeated Tigers (42-84), 9-3 | Tiger Stadium (4-3) | 72-54 | |
| » Starters: Early Wynn vs Ted Gray | Second | 2 out |
| » Lost to Tigers (43-84), 4-1 | Tiger Stadium (4-4) | 72-55 | |
| » Starters: Steve Gromek vs Hal Newhouser | Second | 2 out |
| Friday, August 29 |
| » Defeated Tigers (43-85), 4-2 | Tiger Stadium (5-4) | 73-55 | |
| » Starters: Bob Lemon vs Virgil Trucks | Second | 1 out |
| Saturday, August 30 |
| » Lost to White Sox (67-61), 11-6 | Comiskey Park I (6-4) | 73-56 | |
| » Starters: Bob Feller vs Hal Brown | Second | 2 out |
| Sunday, August 31 |
| » Defeated White Sox (67-62), 6-3 | Comiskey Park I (7-4) | 74-56 | |
| » Starters: Mike Garcia vs Billy Pierce | Second | 2 out |
| Monday, September 1 |
| » Defeated Browns (54-78), 9-3 | Sportsman's Park III (6-4) | 75-56 | Won 2 |
| » Starters: Early Wynn vs Gene Bearden | Second | 2½ out |
| » Lost to Browns (55-78), 2-1 | Sportsman's Park III (6-5) | 75-57 | |
| » Starters: Bob Lemon vs Satchel Paige | Second | 2½ out |
| Wednesday, September 3 |
| » Lost to Tigers (44-89), 11-8 | Cleveland Stadium (33-25) | 75-58 | Lost 2 |
| » Starters: Hal Newhouser vs Bob Feller | Second | 3½ out |
| Thursday, September 4 |
| » Defeated Tigers (44-90), 2-0 | Cleveland Stadium (34-25) | 76-58 | |
| » Starters: Bill Wight vs Mike Garcia | Second | 3½ out |
| Friday, September 5 |
| » Defeated White Sox (70-64), 3-0 | Cleveland Stadium (35-25) | 77-58 | Won 2 |
| » Starters: Billy Pierce vs Early Wynn | Second | 2½ out |
| Saturday, September 6 |
| » Defeated Browns (56-80), 8-3 | Cleveland Stadium (36-25) | 78-58 | Won 3 |
| » Starters: Bob Cain vs Bob Lemon | Second | 2½ out |
| Sunday, September 7 |
| » Defeated Browns (56-81), 4-0 | Cleveland Stadium (37-25) | 79-58 | Won 4 |
| » Starters: Gene Bearden vs Mike Garcia | Second | 2 out |
| » Defeated Browns (56-82), 3-1 | Cleveland Stadium (38-25) | 80-58 | Won 5 |
| » Starters: Tommy Byrne vs Steve Gromek | Second | 2 out |
| Tuesday, September 9 |
| » Defeated Athletics (71-68), 6-1 | Cleveland Stadium (39-25) | 81-58 | Won 6 |
| » Starters: Bobby Shantz vs Early Wynn | Second | 1 out |
| Wednesday, September 10 |
| » Defeated Athletics (71-69), 5-3 | Cleveland Stadium (40-25) | 82-58 | Won 7 |
| » Starters: Alex Kellner vs Bob Lemon | Second | 1 out |
| Thursday, September 11 |
| » Defeated Athletics (71-70), 1-0 | Cleveland Stadium (41-25) | 83-58 | Won 8 |
| » Starters: Harry Byrd vs Mike Garcia | Second | ½ out |
| Friday, September 12 |
| » Defeated Red Sox (72-68), 5-0 | Cleveland Stadium (42-25) | 84-58 | Won 9 |
| » Starters: Sid Hudson vs Early Wynn | Second | ½ out |
| Saturday, September 13 |
| » Lost to Red Sox (73-68), 4-3 | Cleveland Stadium (42-26) | 84-59 | |
| » Starters: Ellis Kinder vs Bob Lemon | Second | 1½ out |
| Sunday, September 14 |
| » Lost to Yankees (86-57), 7-1 | Cleveland Stadium (42-27) | 84-60 | Lost 2 |
| » Starters: Ed Lopat vs Mike Garcia | Second | 2½ out |
| Tuesday, September 16 |
| » Defeated Senators (74-72), 4-3 | Cleveland Stadium (43-27) | 85-60 | |
| » Starters: Bob Porterfield vs Mike Garcia | Second | 2½ out |
| Wednesday, September 17 |
| » Defeated Senators (74-73), 6-1 | Cleveland Stadium (44-27) | 86-60 | Won 2 |
| » Starters: Walt Masterson vs Bob Lemon | Second | 2½ out |
| Friday, September 19 |
| » Defeated Tigers (49-97), 4-1 | Cleveland Stadium (45-27) | 87-60 | Won 3 |
| » Starters: Hal Newhouser vs Early Wynn | Second | 1½ out |
| Saturday, September 20 |
| » Defeated Tigers (49-98), 11-3 | Cleveland Stadium (46-27) | 88-60 | Won 4 |
| » Starters: Ted Gray vs Mike Garcia | Second | 1½ out |
| Sunday, September 21 |
| » Defeated Tigers (49-99), 7-1 | Cleveland Stadium (47-27) | 89-60 | Won 5 |
| » Starters: Art Houtteman vs Bob Lemon | Second | 1½ out |
| Future Indian Gary Gray is born in New Orleans, LA. |
| Monday, September 22 |
| » Defeated Tigers (49-100), 6-3 | Cleveland Stadium (48-27) | 90-60 | Won 6 |
| » Starters: Virgil Trucks vs Early Wynn | Second | 1 out |
| Future Indian Dell Alston is born in Valhalla, NY. |
| Tuesday, September 23 |
| » Lost to White Sox (79-71), 10-1 | Cleveland Stadium (48-28) | 90-61 | |
| » Starters: Joe Dobson vs Mike Garcia | Second | 1½ out |
| Wednesday, September 24 |
| » Defeated White Sox (79-72), 6-0 | Cleveland Stadium (49-28) | 91-61 | |
| » Starters: Lou Kretlow vs Bob Lemon | Second | 2 out |
| Thursday, September 25 |
| Future Indian Mike Stanton is born in Phenix City, AL. |
| Saturday, September 27 |
| » Defeated Tigers (50-103), 11-6 | Tiger Stadium (6-4) | 92-61 | Won 2 |
| » Starters: Bob Chakales vs Virgil Trucks | Second | 3 out |
| Sunday, September 28 |
| » Defeated Tigers (50-104), 8-2 | Tiger Stadium (7-4) | 93-61 | Won 3 |
| » Starters: Dick Rozek vs Ted Gray | Second | 2 out |
| Thursday, October 30 |
| Future Indian Tom Brennan is born in Chicago, IL. |
| Saturday, November 8 |
| Future Indian John Denny is born in Prescott, AZ. |
| Tuesday, November 18 |
| Future Indian Dan Briggs is born in Scotia, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |
