| Thursday, March 2 |
| Future Senator Pete Broberg is born in West Palm Beach, FL. |
| Sunday, April 9 |
| Former Senator John McDonald dies in Roselle, NJ at the age of 68. |
| Tuesday, April 18 |
| » Defeated Athletics (0-1), 8-7 | Griffith Stadium (1-0) | 1-0 | |
| » Starters: Carl Scheib vs Rae Scarborough | First | -- |
| » Major-league debuts: Irv Noren (Senators) |
| Wednesday, April 19 |
| » Lost to Athletics (1-1), 6-1 | Griffith Stadium (1-1) | 1-1 | |
| » Starters: Hank Wyse vs Sid Hudson | Fourth | 1 out |
| » Major-league debuts: Bob Hooper (Athletics) |
| Friday, April 21 |
| » Lost to Yankees (3-1), 14-7 | Yankee Stadium (0-1) | 1-2 | Lost 2 |
| » Starters: Joe Haynes vs Tommy Byrne | Fifth | 2 out |
| » Major-league debuts: Connie Marrero (Senators) |
| Saturday, April 22 |
| » Defeated Yankees (3-2), 7-6 | Yankee Stadium (1-1) | 2-2 | |
| » Starters: Steve Nagy vs Bob Porterfield | Fourth | 2 out |
| Sunday, April 23 |
| » Major-league debuts: Jim Busby (White Sox) |
| Monday, April 24 |
| » Defeated Red Sox (3-5), 3-0 | Griffith Stadium (2-1) | 3-2 | Won 2 |
| » Starters: Al Papai vs Rae Scarborough | Second | 1 out |
| Tuesday, April 25 |
| » Major-league debuts: Lou Sleater (Browns) |
| Wednesday, April 26 |
| » Defeated Athletics (3-5), 5-3 | Shibe Park (1-0) | 4-2 | Won 3 |
| » Starters: Sid Hudson vs Bobby Shantz | Third | 1½ out |
| Thursday, April 27 |
| » Lost to Athletics (4-5), 4-3 | Shibe Park (1-1) | 4-3 | |
| » Starters: Joe Haynes vs Hank Wyse | Fourth | 2 out |
| Friday, April 28 |
| » Defeated Yankees (5-4), 5-4 | Griffith Stadium (3-1) | 5-3 | |
| » Starters: Fred Sanford vs Steve Nagy | Third | 1 out |
| Saturday, April 29 |
| » Lost to Yankees (6-4), 6-2 | Griffith Stadium (3-2) | 5-4 | |
| » Starters: Allie Reynolds vs Rae Scarborough | Fourth | 1½ out |
| Wednesday, May 3 |
| » Defeated Browns (3-6), 4-3 | Griffith Stadium (4-2) | 6-4 | |
| » Starters: Ned Garver vs Sid Hudson | Fourth | ½ out |
| Thursday, May 4 |
| » Lost to Browns (4-6), 5-1 | Griffith Stadium (4-3) | 6-5 | |
| » Starters: Joe Ostrowski vs Dick Weik | Fourth | 1½ out |
| Friday, May 5 |
| » Lost to Tigers (8-3), 9-6 | Griffith Stadium (4-4) | 6-6 | Lost 2 |
| » Starters: Virgil Trucks vs Steve Nagy | Fifth | 2½ out |
| Saturday, May 6 |
| » Lost to Tigers (9-3), 8-6 | Griffith Stadium (4-5) | 6-7 | Lost 3 |
| » Starters: Fred Hutchinson vs Rae Scarborough | Fifth | 3½ out |
| Sunday, May 7 |
| » Defeated Indians (6-7), 10-5 | Griffith Stadium (5-5) | 7-7 | |
| » Starters: Mike Garcia vs Connie Marrero | Fourth | 2½ out |
| Monday, May 8 |
| » Defeated Indians (6-8), 4-2 | Griffith Stadium (6-5) | 8-7 | Won 2 |
| » Starters: Bob Feller vs Sid Hudson | Fourth | 2½ out |
| Tuesday, May 9 |
| » Defeated White Sox (4-9), 3-2 | Griffith Stadium (7-5) | 9-7 | Won 3 |
| » Starters: Mickey Haefner vs Lloyd Hittle | Fourth | 2½ out |
| » Major-league debuts: Joe Erautt (White Sox) |
| Wednesday, May 10 |
| » Defeated White Sox (4-10), 7-6 | Griffith Stadium (8-5) | 10-7 | Won 4 |
| » Starters: Bob Kuzava vs Steve Nagy | Third | 2 out |
| Thursday, May 11 |
| » Defeated White Sox (4-11), 8-5 | Griffith Stadium (9-5) | 11-7 | Won 5 |
| » Starters: Billy Pierce vs Joe Haynes | Third | 1½ out |
| Friday, May 12 |
| » Lost to Red Sox (15-9), 3-1 | Fenway Park (0-1) | 11-8 | |
| » Starters: Rae Scarborough vs Mickey McDermott | Fourth | 2 out |
| Saturday, May 13 |
| » Lost to Red Sox (16-9), 5-4 | Fenway Park (0-2) | 11-9 | Lost 2 |
| » Starters: Sid Hudson vs Chuck Stobbs | Fourth | 3 out |
| Sunday, May 14 |
| » Lost to Red Sox (17-9), 8-1 | Fenway Park (0-3) | 11-10 | Lost 3 |
| » Starters: Lloyd Hittle vs Mel Parnell | Fourth | 2½ out |
| » Defeated Red Sox (17-10), 10-5 | Fenway Park (1-3) | 12-10 | |
| » Starters: Dick Weik vs Al Papai | Fourth | 2½ out |
| Tuesday, May 16 |
| » Defeated White Sox (5-15), 6-5 | Comiskey Park I (1-0) | 13-10 | Won 2 |
| » Starters: Joe Haynes vs Bill Wight | Fourth | 2 out |
| Wednesday, May 17 |
| » Defeated White Sox (5-16), 2-0 | Comiskey Park I (2-0) | 14-10 | Won 3 |
| » Starters: Rae Scarborough vs Bob Kuzava | Fourth | 2 out |
| Thursday, May 18 |
| » Defeated White Sox (5-17), 7-3 | Comiskey Park I (3-0) | 15-10 | Won 4 |
| » Starters: Sid Hudson vs Randy Gumpert | Fourth | 1½ out |
| Saturday, May 20 |
| » Lost to Browns (6-15), 3-0 | Sportsman's Park III (0-1) | 15-11 | |
| » Starters: Dick Weik vs Ned Garver | Fourth | 3 out |
| Sunday, May 21 |
| » Defeated Tigers (16-9), 6-2 | Tiger Stadium (1-0) | 16-11 | |
| » Starters: Connie Marrero vs Ted Gray | Third | 3½ out |
| Monday, May 22 |
| » Lost to Tigers (17-9), 5-1 | Tiger Stadium (1-1) | 16-12 | |
| » Starters: Rae Scarborough vs Hal Newhouser | Fourth | 4½ out |
| Tuesday, May 23 |
| » Defeated Tigers (17-10), 8-2 | Tiger Stadium (2-1) | 17-12 | |
| » Starters: Sid Hudson vs Fred Hutchinson | Third | 4 out |
| Wednesday, May 24 |
| » Lost to Indians (16-14), 5-4 | Cleveland Stadium (0-1) | 17-13 | |
| » Starters: Steve Nagy vs Early Wynn | Fourth | 4½ out |
| Thursday, May 25 |
| » Lost to Indians (17-14), 3-0 | Cleveland Stadium (0-2) | 17-14 | Lost 2 |
| » Starters: Dick Weik vs Bob Lemon | Fourth | 5½ out |
| Saturday, May 27 |
| » Lost to Red Sox (23-15), 4-3 | Griffith Stadium (9-6) | 17-15 | Lost 3 |
| » Starters: Joe Dobson vs Connie Marrero | Fifth | 6½ out |
| » Lost to Red Sox (24-15), 6-2 | Griffith Stadium (9-7) | 17-16 | Lost 4 |
| » Starters: Chuck Stobbs vs Rae Scarborough | Fifth | 6½ out |
| Sunday, May 28 |
| » Defeated Red Sox (24-16), 7-6 | Griffith Stadium (10-7) | 18-16 | |
| » Starters: Mickey McDermott vs Sid Hudson | Fifth | 6 out |
| Tuesday, May 30 |
| » Defeated Athletics (13-24), 4-3 | Shibe Park (2-1) | 19-16 | Won 2 |
| » Starters: Dick Weik vs Bobby Shantz | Fifth | 7 out |
| » Lost to Athletics (14-24), 5-1 | Shibe Park (2-2) | 19-17 | |
| » Starters: Steve Nagy vs Bob Hooper | Fifth | 7 out |
| Thursday, June 1 |
| » Lost to Browns (9-25), 5-4 | Griffith Stadium (10-8) | 19-18 | Lost 2 |
| » Starters: Joe Ostrowski vs Connie Marrero | Fifth | 8 out |
| Friday, June 2 |
| » Lost to Browns (10-25), 10-5 | Griffith Stadium (10-9) | 19-19 | Lost 3 |
| » Starters: Al Widmar vs Sid Hudson | Fifth | 8½ out |
| » Lost to Browns (11-25), 9-3 | Griffith Stadium (10-10) | 19-20 | Lost 4 |
| » Starters: Fritz Dorish vs Lloyd Hittle | Fifth | 8½ out |
| Sunday, June 4 |
| » Lost to Tigers (26-12), 3-0 | Griffith Stadium (10-11) | 19-21 | Lost 5 |
| » Starters: Art Houtteman vs Bob Kuzava | Fifth | 10½ out |
| Monday, June 5 |
| » Lost to Tigers (27-12), 7-4 | Griffith Stadium (10-12) | 19-22 | Lost 6 |
| » Starters: Dizzy Trout vs Steve Nagy | Fifth | 10½ out |
| Tuesday, June 6 |
| » Lost to Tigers (28-12), 11-8 | Griffith Stadium (10-13) | 19-23 | Lost 7 |
| » Starters: Fred Hutchinson vs Joe Haynes | Fifth | 10 out |
| Wednesday, June 7 |
| » Defeated Indians (22-21), 5-4 | Griffith Stadium (11-13) | 20-23 | |
| » Starters: Early Wynn vs Sid Hudson | Fifth | 10½ out |
| Thursday, June 8 |
| » Defeated Indians (22-22), 7-6 | Griffith Stadium (12-13) | 21-23 | Won 2 |
| » Starters: Bob Lemon vs Bob Kuzava | Fifth | 10½ out |
| Friday, June 9 |
| » Lost to Indians (23-22), 8-7 | Griffith Stadium (12-14) | 21-24 | |
| » Starters: Bob Feller vs Connie Marrero | Fifth | 10½ out |
| Saturday, June 10 |
| » Defeated White Sox (16-31), 6-0 | Griffith Stadium (13-14) | 22-24 | |
| » Starters: Billy Pierce vs Sandy Consuegra | Fifth | 9 out |
| » Major-league debuts: Sandy Consuegra (Senators) |
| Sunday, June 11 |
| » Lost to White Sox (17-31), 8-3 | Griffith Stadium (13-15) | 22-25 | |
| » Starters: Ken Holcombe vs Steve Nagy | Fifth | 11 out |
| » Lost to White Sox (18-31), 5-4 | Griffith Stadium (13-16) | 22-26 | Lost 2 |
| » Starters: Rae Scarborough vs Lloyd Hittle | Fifth | 11 out |
| Tuesday, June 13 |
| » Lost to Browns (16-30), 8-3 | Sportsman's Park III (0-2) | 22-27 | Lost 3 |
| » Starters: Sid Hudson vs Fritz Dorish | Fifth | 12½ out |
| » Lost to Browns (17-30), 6-1 | Sportsman's Park III (0-3) | 22-28 | Lost 4 |
| » Starters: Bob Kuzava vs Cliff Fannin | Fifth | 12½ out |
| Wednesday, June 14 |
| » Defeated Browns (17-31), 4-1 | Sportsman's Park III (1-3) | 23-28 | |
| » Starters: Connie Marrero vs Ned Garver | Fifth | 11½ out |
| Future Senator Bill Fahey is born in Detroit, MI. |
| Thursday, June 15 |
| » Lost to Browns (18-31), 16-9 | Sportsman's Park III (1-4) | 23-29 | |
| » Starters: Sandy Consuegra vs Dick Starr | Fifth | 12½ out |
| Friday, June 16 |
| » Lost to White Sox (22-31), 7-1 | Comiskey Park I (3-1) | 23-30 | Lost 2 |
| » Starters: Steve Nagy vs Rae Scarborough | Fifth | 13½ out |
| Saturday, June 17 |
| » Defeated White Sox (22-32), 6-3 | Comiskey Park I (4-1) | 24-30 | |
| » Starters: Bob Kuzava vs Ken Holcombe | Fifth | 13½ out |
| Monday, June 19 |
| » Lost to White Sox (23-32), 4-3 | Comiskey Park I (4-2) | 24-31 | |
| » Starters: Sid Hudson vs Bob Cain | Fifth | 14½ out |
| Tuesday, June 20 |
| » Defeated Tigers (37-16), 4-2 | Tiger Stadium (3-1) | 25-31 | |
| » Starters: Connie Marrero vs Fred Hutchinson | Fifth | 13½ out |
| Wednesday, June 21 |
| » Defeated Tigers (37-17), 12-4 | Tiger Stadium (4-1) | 26-31 | Won 2 |
| » Starters: Sandy Consuegra vs Hal Newhouser | Fifth | 12½ out |
| Thursday, June 22 |
| » Defeated Tigers (37-18), 5-2 | Tiger Stadium (5-1) | 27-31 | Won 3 |
| » Starters: Bob Kuzava vs Dizzy Trout | Fifth | 11½ out |
| Friday, June 23 |
| » Lost to Indians (34-25), 13-4 | Cleveland Stadium (0-3) | 27-32 | |
| » Starters: Bob Ross vs Bob Lemon | Fifth | 12½ out |
| Saturday, June 24 |
| » Lost to Indians (35-25), 6-5 | Cleveland Stadium (0-4) | 27-33 | Lost 2 |
| » Starters: Sid Hudson vs Gene Bearden | Fifth | 13½ out |
| Sunday, June 25 |
| » Lost to Indians (36-25), 7-6 | Cleveland Stadium (0-5) | 27-34 | Lost 3 |
| » Starters: Connie Marrero vs Early Wynn | Fifth | 13½ out |
| » Defeated Indians (36-26), 5-3 | Cleveland Stadium (1-5) | 28-34 | |
| » Starters: Sandy Consuegra vs Dick Weik | Fifth | 13½ out |
| Tuesday, June 27 |
| » Defeated Yankees (39-25), 4-3 | Yankee Stadium (2-1) | 29-34 | Won 2 |
| » Starters: Bob Kuzava vs Tommy Byrne | Fifth | 14 out |
| Wednesday, June 28 |
| » Lost to Yankees (40-25), 5-1 | Yankee Stadium (2-2) | 29-35 | |
| » Starters: Al Sima vs Allie Reynolds | Fifth | 15 out |
| » Major-league debuts: Al Sima (Senators) |
| Thursday, June 29 |
| » Defeated Yankees (40-26), 12-7 | Yankee Stadium (3-2) | 30-35 | |
| » Starters: Sid Hudson vs Joe Ostrowski | Fifth | 14 out |
| Friday, June 30 |
| » Lost to Athletics (23-44), 7-6 | Griffith Stadium (13-17) | 30-36 | |
| » Starters: Hank Wyse vs Connie Marrero | Fifth | 14½ out |
| » Lost to Athletics (24-44), 4-2 | Griffith Stadium (13-18) | 30-37 | Lost 2 |
| » Starters: Alex Kellner vs Sandy Consuegra | Fifth | 14½ out |
| Saturday, July 1 |
| » Defeated Athletics (24-45), 3-2 | Griffith Stadium (14-18) | 31-37 | |
| » Starters: Bobby Shantz vs Bob Ross | Fifth | 13½ out |
| Sunday, July 2 |
| » Lost to Athletics (25-45), 7-4 | Griffith Stadium (14-19) | 31-38 | |
| » Starters: Bob Hooper vs Bob Kuzava | Fifth | 14 out |
| Monday, July 3 |
| » Defeated Yankees (42-29), 7-2 | Griffith Stadium (15-19) | 32-38 | |
| » Starters: Fred Sanford vs Al Sima | Fifth | 14 out |
| Tuesday, July 4 |
| » Lost to Yankees (43-29), 16-9 | Griffith Stadium (15-20) | 32-39 | |
| » Starters: Vic Raschi vs Sid Hudson | Fifth | 14½ out |
| » Tied Yankees, 3-3 | Griffith Stadium (15-20) | 32-39 | |
| » Starters: Eddie Lopat vs Bob Kuzava | Fifth | 14½ out |
| Wednesday, July 5 |
| » Defeated Red Sox (41-33), 9-7 | Fenway Park (2-3) | 33-39 | |
| » Starters: Sandy Consuegra vs Chuck Stobbs | Fifth | 14½ out |
| Friday, July 7 |
| » Defeated Athletics (25-48), 7-5 | Shibe Park (3-2) | 34-39 | Won 2 |
| » Starters: Connie Marrero vs Bob Hooper | Fifth | 14½ out |
| Saturday, July 8 |
| » Lost to Athletics (26-48), 6-0 | Shibe Park (3-3) | 34-40 | |
| » Starters: Al Sima vs Lou Brissie | Fifth | 15½ out |
| Sunday, July 9 |
| » Lost to Athletics (27-48), 6-5 | Shibe Park (3-4) | 34-41 | Lost 2 |
| » Starters: Sid Hudson vs Dick Fowler | Fifth | 14½ out |
| » Defeated Athletics (27-49), 2-0 | Shibe Park (4-4) | 35-41 | |
| » Starters: Bob Kuzava vs Alex Kellner | Fifth | 14½ out |
| Thursday, July 13 |
| » Lost to Tigers (50-26), 5-2 | Griffith Stadium (15-21) | 35-42 | |
| » Starters: Hal Newhouser vs Sandy Consuegra | Fifth | 15½ out |
| Friday, July 14 |
| » Lost to Tigers (51-26), 2-0 | Griffith Stadium (15-22) | 35-43 | Lost 2 |
| » Starters: Fred Hutchinson vs Connie Marrero | Fifth | 16½ out |
| Sunday, July 16 |
| » Defeated Browns (29-51), 5-1 | Griffith Stadium (16-22) | 36-43 | |
| » Starters: Stubby Overmire vs Sid Hudson | Fifth | 16½ out |
| » Lost to Browns (30-51), 10-8 | Griffith Stadium (16-23) | 36-44 | |
| » Starters: Fritz Dorish vs Rogelio Martinez | Fifth | 16½ out |
| Monday, July 17 |
| » Defeated Browns (30-52), 3-1 | Griffith Stadium (17-23) | 37-44 | |
| » Starters: Duane Pillette vs Bob Kuzava | Fifth | 17 out |
| Tuesday, July 18 |
| » Defeated White Sox (36-50), 5-2 | Griffith Stadium (18-23) | 38-44 | Won 2 |
| » Starters: Rae Scarborough vs Sandy Consuegra | Fifth | 16 out |
| Wednesday, July 19 |
| » Defeated White Sox (36-51), 5-4 | Griffith Stadium (19-23) | 39-44 | Won 3 |
| » Starters: Randy Gumpert vs Jim Pearce | Fifth | 16 out |
| Friday, July 21 |
| » Defeated Indians (52-36), 3-2 | Griffith Stadium (20-23) | 40-44 | Won 4 |
| » Starters: Mike Garcia vs Connie Marrero | Fifth | 14½ out |
| Saturday, July 22 |
| » Lost to Indians (53-36), 8-3 | Griffith Stadium (20-24) | 40-45 | |
| » Starters: Early Wynn vs Sid Hudson | Fifth | 14½ out |
| Sunday, July 23 |
| » Lost to Indians (54-36), 6-2 | Griffith Stadium (20-25) | 40-46 | Lost 2 |
| » Starters: Bob Lemon vs Bob Kuzava | Fifth | 15½ out |
| Tuesday, July 25 |
| » Defeated White Sox (37-55), 7-4 | Comiskey Park I (5-2) | 41-46 | |
| » Starters: Jim Pearce vs Bob Cain | Fifth | 14½ out |
| Thursday, July 27 |
| » Defeated White Sox (37-56), 3-2 | Comiskey Park I (6-2) | 42-46 | Won 2 |
| » Starters: Sid Hudson vs Billy Pierce | Fifth | 14½ out |
| » Lost to White Sox (38-56), 6-3 | Comiskey Park I (6-3) | 42-47 | |
| » Starters: Connie Marrero vs Randy Gumpert | Fifth | 14½ out |
| Friday, July 28 |
| » Lost to Browns (33-59), 5-4 | Sportsman's Park III (1-5) | 42-48 | Lost 2 |
| » Starters: Bob Kuzava vs Fritz Dorish | Fifth | 14½ out |
| Saturday, July 29 |
| » Lost to Browns (34-59), 10-9 | Sportsman's Park III (1-6) | 42-49 | Lost 3 |
| » Starters: Sandy Consuegra vs Cuddles Marshall | Fifth | 15½ out |
| Sunday, July 30 |
| » Defeated Browns (34-60), 9-5 | Sportsman's Park III (2-6) | 43-49 | |
| » Starters: Joe Haynes vs Stubby Overmire | Fifth | 15 out |
| » Defeated Browns (34-61), 13-8 | Sportsman's Park III (3-6) | 44-49 | Won 2 |
| » Starters: Elmer Singleton vs Ned Garver | Fifth | 15 out |
| Tuesday, August 1 |
| » Lost to Indians (60-38), 8-2 | Cleveland Stadium (1-6) | 44-50 | |
| » Starters: Sid Hudson vs Early Wynn | Fifth | 16 out |
| Wednesday, August 2 |
| » Lost to Indians (61-38), 11-0 | Cleveland Stadium (1-7) | 44-51 | Lost 2 |
| » Starters: Connie Marrero vs Bob Lemon | Fifth | 17 out |
| Friday, August 4 |
| » Defeated Tigers (62-35), 5-2 | Tiger Stadium (6-1) | 45-51 | |
| » Starters: Bob Kuzava vs Ted Gray | Fifth | 16½ out |
| Saturday, August 5 |
| » Lost to Tigers (63-35), 9-8 | Tiger Stadium (6-2) | 45-52 | |
| » Starters: Sandy Consuegra vs Fred Hutchinson | Fifth | 17½ out |
| Sunday, August 6 |
| » Lost to Tigers (64-35), 4-0 | Tiger Stadium (6-3) | 45-53 | Lost 2 |
| » Starters: Gene Bearden vs Dizzy Trout | Fifth | 18½ out |
| Tuesday, August 8 |
| » Lost to Athletics (37-66), 5-0 | Shibe Park (4-5) | 45-54 | Lost 3 |
| » Starters: Sid Hudson vs Lou Brissie | Fourth | 18½ out |
| Wednesday, August 9 |
| » Lost to Athletics (38-66), 7-6 | Shibe Park (4-6) | 45-55 | Lost 4 |
| » Starters: Connie Marrero vs Hank Wyse | Fifth | 19½ out |
| Thursday, August 10 |
| » Defeated Red Sox (60-46), 11-2 | Griffith Stadium (21-25) | 46-55 | |
| » Starters: Willard Nixon vs Bob Kuzava | Fifth | 20 out |
| » Lost to Red Sox (61-46), 4-3 | Griffith Stadium (21-26) | 46-56 | |
| » Starters: Walt Masterson vs Gene Bearden | Fifth | 20 out |
| Friday, August 11 |
| » Defeated Red Sox (61-47), 5-2 | Griffith Stadium (22-26) | 47-56 | |
| » Starters: Ellis Kinder vs Sandy Consuegra | Fifth | 19½ out |
| Saturday, August 12 |
| » Lost to Red Sox (62-47), 10-1 | Griffith Stadium (22-27) | 47-57 | |
| » Starters: Joe Dobson vs Sid Hudson | Fifth | 20 out |
| Sunday, August 13 |
| » Defeated Red Sox (62-48), 6-5 | Griffith Stadium (23-27) | 48-57 | |
| » Starters: Mickey McDermott vs Al Sima | Fifth | 19½ out |
| Tuesday, August 15 |
| » Defeated Yankees (65-43), 10-5 | Griffith Stadium (24-27) | 49-57 | Won 2 |
| » Starters: Eddie Lopat vs Gene Bearden | Fifth | 19½ out |
| » Lost to Yankees (66-43), 9-0 | Griffith Stadium (24-28) | 49-58 | |
| » Starters: Whitey Ford vs Bob Kuzava | Fifth | 19½ out |
| Wednesday, August 16 |
| » Lost to Yankees (67-43), 9-4 | Griffith Stadium (24-29) | 49-59 | Lost 2 |
| » Starters: Tommy Byrne vs Sandy Consuegra | Fifth | 20½ out |
| Thursday, August 17 |
| » Defeated Yankees (67-44), 2-1 | Griffith Stadium (25-29) | 50-59 | |
| » Starters: Allie Reynolds vs Sid Hudson | Fifth | 20½ out |
| Friday, August 18 |
| » Lost to Red Sox (68-48), 7-6 | Fenway Park (2-4) | 50-60 | |
| » Starters: Al Sima vs Joe Dobson | Fifth | 21 out |
| Saturday, August 19 |
| » Lost to Red Sox (69-48), 5-4 | Fenway Park (2-5) | 50-61 | Lost 2 |
| » Starters: Connie Marrero vs Mel Parnell | Fifth | 22 out |
| Tuesday, August 22 |
| » Lost to Indians (72-46), 5-1 | Griffith Stadium (25-30) | 50-62 | Lost 3 |
| » Starters: Bob Feller vs Gene Bearden | Fifth | 22½ out |
| Thursday, August 24 |
| » Lost to Indians (73-46), 3-1 | Griffith Stadium (25-31) | 50-63 | Lost 4 |
| » Starters: Early Wynn vs Sid Hudson | Fifth | 23½ out |
| » Lost to Indians (74-46), 5-3 | Griffith Stadium (25-32) | 50-64 | Lost 5 |
| » Starters: Bob Lemon vs Sandy Consuegra | Fifth | 23½ out |
| Friday, August 25 |
| » Lost to White Sox (48-72), 6-1 | Griffith Stadium (25-33) | 50-65 | Lost 6 |
| » Starters: Ken Holcombe vs Al Sima | Fifth | 24 out |
| » Lost to White Sox (49-72), 10-5 | Griffith Stadium (25-34) | 50-66 | Lost 7 |
| » Starters: Billy Pierce vs Connie Marrero | Fifth | 24 out |
| Saturday, August 26 |
| » Defeated White Sox (49-73), 7-6 | Griffith Stadium (26-34) | 51-66 | |
| » Starters: Bill Wight vs Gene Bearden | Fifth | 24 out |
| Sunday, August 27 |
| » Defeated Browns (39-79), 8-0 | Griffith Stadium (27-34) | 52-66 | Won 2 |
| » Starters: Al Widmar vs Joe Haynes | Fifth | 24 out |
| » Lost to Browns (40-79), 11-10 | Griffith Stadium (27-35) | 52-67 | |
| » Starters: Don Johnson vs Bob Kuzava | Fifth | 24 out |
| Monday, August 28 |
| » Defeated Browns (40-80), 9-3 | Griffith Stadium (28-35) | 53-67 | |
| » Starters: Jack Bruner vs Jim Pearce | Fifth | 23 out |
| Tuesday, August 29 |
| » Defeated Tigers (76-45), 5-4 | Griffith Stadium (29-35) | 54-67 | Won 2 |
| » Starters: Dizzy Trout vs Sid Hudson | Fourth | 22 out |
| Wednesday, August 30 |
| » Defeated Tigers (76-46), 3-2 | Griffith Stadium (30-35) | 55-67 | Won 3 |
| » Starters: Fred Hutchinson vs Sandy Consuegra | Fifth | 23 out |
| » Lost to Tigers (77-46), 10-8 | Griffith Stadium (30-36) | 55-68 | |
| » Starters: Hank Borowy vs Bob Kuzava | Fifth | 23 out |
| Thursday, August 31 |
| » Defeated Tigers (77-47), 2-1 | Griffith Stadium (31-36) | 56-68 | |
| » Starters: Art Houtteman vs Gene Bearden | Fifth | 23 out |
| Friday, September 1 |
| » Lost to Yankees (81-46), 6-2 | Yankee Stadium (3-3) | 56-69 | |
| » Starters: Al Sima vs Allie Reynolds | Fifth | 24 out |
| Saturday, September 2 |
| » Lost to Yankees (82-46), 9-2 | Yankee Stadium (3-4) | 56-70 | Lost 2 |
| » Starters: Joe Haynes vs Joe Ostrowski | Fifth | 25 out |
| Monday, September 4 |
| » Lost to Red Sox (80-50), 5-4 | Griffith Stadium (31-37) | 56-71 | Lost 3 |
| » Starters: Joe Dobson vs Sid Hudson | Fifth | 25 out |
| » Defeated Red Sox (80-51), 5-3 | Griffith Stadium (32-37) | 57-71 | |
| » Starters: Willard Nixon vs Bob Kuzava | Fifth | 25 out |
| Wednesday, September 6 |
| » Defeated Athletics (46-87), 3-0 | Griffith Stadium (33-37) | 58-71 | Won 2 |
| » Starters: Bobby Shantz vs Sandy Consuegra | Fifth | 24 out |
| Thursday, September 7 |
| » Lost to Athletics (47-87), 4-2 | Griffith Stadium (33-38) | 58-72 | |
| » Starters: Hank Wyse vs Gene Bearden | Fifth | 24 out |
| Friday, September 8 |
| » Defeated Athletics (47-88), 10-4 | Griffith Stadium (34-38) | 59-72 | |
| » Starters: Joe Murray vs Julio Moreno | Fifth | 24 out |
| » Major-league debuts: Julio Moreno (Senators) |
| Sunday, September 10 |
| » Lost to Yankees (84-49), 8-1 | Griffith Stadium (34-39) | 59-73 | |
| » Starters: Vic Raschi vs Sid Hudson | Fifth | 25 out |
| Monday, September 11 |
| » Lost to Yankees (85-49), 5-1 | Griffith Stadium (34-40) | 59-74 | Lost 2 |
| » Starters: Whitey Ford vs Al Sima | Fifth | 26½ out |
| » Lost to Yankees (86-49), 6-2 | Griffith Stadium (34-41) | 59-75 | Lost 3 |
| » Starters: Tommy Byrne vs Sandy Consuegra | Fifth | 26½ out |
| Tuesday, September 12 |
| » Lost to Tigers (86-49), 3-2 | Tiger Stadium (6-4) | 59-76 | Lost 4 |
| » Starters: Gene Bearden vs Dizzy Trout | Fifth | 27 out |
| Wednesday, September 13 |
| » Lost to Tigers (87-49), 6-1 | Tiger Stadium (6-5) | 59-77 | Lost 5 |
| » Starters: Bob Kuzava vs Fred Hutchinson | Fifth | 28 out |
| Friday, September 15 |
| » Lost to Indians (82-59), 4-2 | Cleveland Stadium (1-8) | 59-78 | Lost 6 |
| » Starters: Julio Moreno vs Al Aber | Fifth | 28 out |
| » Defeated Indians (82-60), 4-1 | Cleveland Stadium (2-8) | 60-78 | |
| » Starters: Sid Hudson vs Mike Garcia | Fifth | 28 out |
| » Major-league debuts: Al Aber (Indians) |
| Saturday, September 16 |
| » Lost to Indians (83-60), 5-1 | Cleveland Stadium (2-9) | 60-79 | |
| » Starters: Sandy Consuegra vs Bob Feller | Fifth | 28½ out |
| Sunday, September 17 |
| » Lost to White Sox (56-87), 4-0 | Comiskey Park I (6-4) | 60-80 | Lost 2 |
| » Starters: Connie Marrero vs Bill Wight | Fifth | 28½ out |
| » Defeated White Sox (56-88), 3-2 | Comiskey Park I (7-4) | 61-80 | |
| » Starters: Bob Kuzava vs Randy Gumpert | Fifth | 28½ out |
| Tuesday, September 19 |
| » Defeated Browns (54-89), 5-3 | Sportsman's Park III (4-6) | 62-80 | Won 2 |
| » Starters: Joe Haynes vs Ned Garver | Fourth | 27½ out |
| Wednesday, September 20 |
| » Defeated Browns (54-90), 12-7 | Sportsman's Park III (5-6) | 63-80 | Won 3 |
| » Starters: Sid Hudson vs Dick Starr | Fifth | 27½ out |
| Saturday, September 23 |
| » Lost to Athletics (50-98), 16-5 | Griffith Stadium (34-42) | 63-81 | |
| » Starters: Hank Wyse vs Julio Moreno | Fifth | 28½ out |
| Sunday, September 24 |
| » Defeated Athletics (50-99), 3-1 | Griffith Stadium (35-42) | 64-81 | |
| » Starters: Johnny Kucab vs Carlos Pascual | Fifth | 28½ out |
| » Major-league debuts: Carlos Pascual (Senators) |
| Monday, September 25 |
| » Lost to Yankees (94-53), 8-3 | Yankee Stadium (3-5) | 64-82 | |
| » Starters: Sandy Consuegra vs Allie Reynolds | Fifth | 30½ out |
| » Lost to Yankees (95-53), 7-4 | Yankee Stadium (3-6) | 64-83 | Lost 2 |
| » Starters: Bob Kuzava vs Whitey Ford | Fifth | 30½ out |
| Tuesday, September 26 |
| » Defeated Yankees (95-54), 11-9 | Yankee Stadium (4-6) | 65-83 | |
| » Starters: Al Sima vs Tommy Byrne | Fifth | 30½ out |
| » Lost to Yankees (96-54), 10-7 | Yankee Stadium (4-7) | 65-84 | |
| » Starters: Sid Hudson vs Joe Ostrowski | Fifth | 30½ out |
| » Major-league debuts: Lew Burdette Dave Madison and Ernie Nevel (Yankees) |
| Wednesday, September 27 |
| » Defeated Red Sox (91-58), 2-0 | Fenway Park (3-5) | 66-84 | |
| » Starters: Connie Marrero vs Joe Dobson | Fifth | 29 out |
| » Defeated Red Sox (91-59), 6-3 | Fenway Park (4-5) | 67-84 | Won 2 |
| » Starters: Gene Bearden vs Willard Nixon | Fifth | 29 out |
| Thursday, September 28 |
| » Lost to Red Sox (92-59), 4-3 | Fenway Park (4-6) | 67-85 | |
| » Starters: Carlos Pascual vs Chuck Stobbs | Fifth | 30 out |
| Friday, September 29 |
| » Lost to Red Sox (93-59), 7-6 | Fenway Park (4-7) | 67-86 | Lost 2 |
| » Starters: Bob Kuzava vs Walt Masterson | Fifth | 30½ out |
| Sunday, October 1 |
| » Lost to Athletics (52-102), 5-3 | Shibe Park (4-7) | 67-87 | Lost 3 |
| » Starters: Joe Haynes vs Johnny Kucab | Fifth | 31 out |
| Thursday, November 16 |
| Former Senator Frank Hemphill dies in Chicago, IL at the age of 73. |
Game information provided by Retrosheet (www.retrosheet.org) |
