| Tuesday, January 3 |
| Future Red Sox Jim Dwyer is born in Evergreen Park, IL. |
| Saturday, February 18 |
| Future Red Sox Bruce Kison is born in Pasco, WA. |
| Sunday, February 26 |
| Future Red Sox Jack Brohamer is born in Maywood, CA. |
| Sunday, March 5 |
| Future Red Sox Doug Bird is born in Corona, CA. |
| Monday, March 27 |
| Future Red Sox Lynn McGlothen is born in Monroe, LA. |
| Tuesday, April 11 |
| Former Red Sox Dick McCabe dies in Buffalo, NY at the age of 55. |
| Tuesday, April 18 |
| » Lost to Yankees (1-0), 15-10 | Fenway Park (0-1) | 0-1 | |
| » Starters: Allie Reynolds vs Mel Parnell | Second | 1 out |
| » Major-league debuts: Jackie Jensen and Billy Martin (Yankees) |
| Wednesday, April 19 |
| » Defeated Yankees (1-1), 6-3 | Fenway Park (1-1) | 1-1 | |
| » Starters: Vic Raschi vs Joe Dobson | Fifth | 1½ out |
| » Lost to Yankees (2-1), 16-7 | Fenway Park (1-2) | 1-2 | |
| » Starters: Eddie Lopat vs Ellis Kinder | Fifth | 1½ out |
| Friday, April 21 |
| » Defeated Athletics (1-2), 8-2 | Shibe Park (1-0) | 2-2 | |
| » Starters: Mickey McDermott vs Lou Brissie | Fourth | 1½ out |
| Saturday, April 22 |
| » Lost to Athletics (2-2), 6-5 | Shibe Park (1-1) | 2-3 | |
| » Starters: Chuck Stobbs vs Alex Kellner | Fifth | 2½ out |
| Sunday, April 23 |
| » Lost to Athletics (3-2), 9-4 | Shibe Park (1-2) | 2-4 | Lost 2 |
| » Starters: Joe Dobson vs Bobby Shantz | Fifth | 2 out |
| » Defeated Athletics (3-3), 12-2 | Shibe Park (2-2) | 3-4 | |
| » Starters: Mel Parnell vs Hank Wyse | Fifth | 2 out |
| » Major-league debuts: Normie Roy (Red Sox) |
| Monday, April 24 |
| » Lost to Senators (3-2), 3-0 | Griffith Stadium (0-1) | 3-5 | |
| » Starters: Al Papai vs Rae Scarborough | Fifth | 2½ out |
| Wednesday, April 26 |
| » Lost to Yankees (5-2), 10-2 | Yankee Stadium (0-1) | 3-6 | Lost 2 |
| » Starters: Mickey McDermott vs Eddie Lopat | Sixth | 4 out |
| Thursday, April 27 |
| » Defeated Yankees (5-3), 7-2 | Yankee Stadium (1-1) | 4-6 | |
| » Starters: Ellis Kinder vs Tommy Byrne | Sixth | 3½ out |
| Friday, April 28 |
| » Defeated Athletics (4-6), 4-1 | Fenway Park (2-2) | 5-6 | Won 2 |
| » Starters: Alex Kellner vs Mel Parnell | Fifth | 2½ out |
| Sunday, April 30 |
| » Defeated Athletics (4-7), 19-0 | Fenway Park (3-2) | 6-6 | Won 3 |
| » Starters: Dick Fowler vs Joe Dobson | Fifth | 2 out |
| » Defeated Athletics (4-8), 6-5 | Fenway Park (4-2) | 7-6 | Won 4 |
| » Starters: Hank Wyse vs Chuck Stobbs | Fifth | 2 out |
| Tuesday, May 2 |
| » Defeated Indians (4-4), 6-1 | Fenway Park (5-2) | 8-6 | Won 5 |
| » Starters: Mike Garcia vs Mickey McDermott | Third | 2½ out |
| Wednesday, May 3 |
| » Defeated Indians (4-5), 7-2 | Fenway Park (6-2) | 9-6 | Won 6 |
| » Starters: Bob Feller vs Ellis Kinder | Third | 3 out |
| Thursday, May 4 |
| » Lost to Indians (5-5), 5-4 | Fenway Park (6-3) | 9-7 | |
| » Starters: Bob Lemon vs Mel Parnell | Third | 3 out |
| Friday, May 5 |
| » Defeated White Sox (3-6), 5-2 | Fenway Park (7-3) | 10-7 | |
| » Starters: Billy Pierce vs Joe Dobson | Second | 3 out |
| Saturday, May 6 |
| » Defeated White Sox (3-7), 11-1 | Fenway Park (8-3) | 11-7 | Won 2 |
| » Starters: Ken Holcombe vs Chuck Stobbs | Second | 3 out |
| Sunday, May 7 |
| » Defeated Browns (4-8), 8-6 | Fenway Park (9-3) | 12-7 | Won 3 |
| » Starters: Ned Garver vs Mickey McDermott | Second | 3½ out |
| » Defeated Browns (4-9), 6-2 | Fenway Park (10-3) | 13-7 | Won 4 |
| » Starters: Cliff Fannin vs Al Papai | Second | 3½ out |
| Tuesday, May 9 |
| » Defeated Tigers (10-5), 6-1 | Fenway Park (11-3) | 14-7 | Won 5 |
| » Starters: Virgil Trucks vs Mel Parnell | First | -- |
| Thursday, May 11 |
| » Lost to Tigers (11-5), 13-4 | Fenway Park (11-4) | 14-8 | |
| » Starters: Fred Hutchinson vs Joe Dobson | Fourth | 3 out |
| » Lost to Tigers (12-5), 5-3 | Fenway Park (11-5) | 14-9 | Lost 2 |
| » Starters: Ted Gray vs Ellis Kinder | Fourth | 3 out |
| Friday, May 12 |
| » Defeated Senators (11-8), 3-1 | Fenway Park (12-5) | 15-9 | |
| » Starters: Rae Scarborough vs Mickey McDermott | Third | 3½ out |
| Saturday, May 13 |
| » Defeated Senators (11-9), 5-4 | Fenway Park (13-5) | 16-9 | Won 2 |
| » Starters: Sid Hudson vs Chuck Stobbs | Third | 3½ out |
| Future Red Sox Juan Beniquez is born in San Sebastian, P.R. |
| Sunday, May 14 |
| » Defeated Senators (11-10), 8-1 | Fenway Park (14-5) | 17-9 | Won 3 |
| » Starters: Lloyd Hittle vs Mel Parnell | Third | 4 out |
| » Lost to Senators (12-10), 10-5 | Fenway Park (14-6) | 17-10 | |
| » Starters: Dick Weik vs Al Papai | Third | 4 out |
| Tuesday, May 16 |
| » Defeated Tigers (13-7), 6-1 | Tiger Stadium (1-0) | 18-10 | |
| » Starters: Joe Dobson vs Art Houtteman | Third | 2½ out |
| Wednesday, May 17 |
| » Lost to Tigers (14-7), 6-3 | Tiger Stadium (1-1) | 18-11 | |
| » Starters: Ellis Kinder vs Ted Gray | Third | 2½ out |
| Thursday, May 18 |
| » Defeated Tigers (14-8), 13-12 | Tiger Stadium (2-1) | 19-11 | |
| » Starters: Mickey McDermott vs Fred Hutchinson | Third | 3 out |
| Friday, May 19 |
| » Lost to Indians (14-11), 4-1 | Cleveland Stadium (0-1) | 19-12 | |
| » Starters: Mel Parnell vs Mike Garcia | Third | 3 out |
| Saturday, May 20 |
| » Lost to Indians (15-11), 8-5 | Cleveland Stadium (0-2) | 19-13 | Lost 2 |
| » Starters: Chuck Stobbs vs Bob Lemon | Third | 3 out |
| » Major-league debuts: Jim Suchecki (Red Sox) |
| Sunday, May 21 |
| » Defeated White Sox (5-20), 7-0 | Comiskey Park I (1-0) | 20-13 | |
| » Starters: Ellis Kinder vs Bill Wight | Fourth | 3 out |
| » Lost to White Sox (6-20), 4-3 | Comiskey Park I (1-1) | 20-14 | |
| » Starters: Joe Dobson vs Billy Pierce | Fourth | 3 out |
| Monday, May 22 |
| » Lost to White Sox (7-20), 10-9 | Comiskey Park I (1-2) | 20-15 | Lost 2 |
| » Starters: Mickey McDermott vs Bob Kuzava | Third | 4 out |
| Wednesday, May 24 |
| » Defeated Browns (8-17), 7-5 | Sportsman's Park III (1-0) | 21-15 | |
| » Starters: Mel Parnell vs Lou Kretlow | Third | 3½ out |
| Thursday, May 25 |
| » Defeated Browns (8-18), 15-12 | Sportsman's Park III (2-0) | 22-15 | Won 2 |
| » Starters: Ellis Kinder vs Ned Garver | Third | 3½ out |
| Saturday, May 27 |
| » Defeated Senators (17-15), 4-3 | Griffith Stadium (1-1) | 23-15 | Won 3 |
| » Starters: Joe Dobson vs Connie Marrero | Third | 3½ out |
| » Defeated Senators (17-16), 6-2 | Griffith Stadium (2-1) | 24-15 | Won 4 |
| » Starters: Chuck Stobbs vs Rae Scarborough | Third | 3½ out |
| Sunday, May 28 |
| » Lost to Senators (18-16), 7-6 | Griffith Stadium (2-2) | 24-16 | |
| » Starters: Mickey McDermott vs Sid Hudson | Third | 3 out |
| Tuesday, May 30 |
| » Lost to Yankees (25-10), 11-7 | Yankee Stadium (1-2) | 24-17 | Lost 2 |
| » Starters: Mel Parnell vs Tommy Byrne | Third | 5 out |
| » Lost to Yankees (26-10), 5-3 | Yankee Stadium (1-3) | 24-18 | Lost 3 |
| » Starters: Ellis Kinder vs Eddie Lopat | Third | 5 out |
| Friday, June 2 |
| » Defeated Indians (20-18), 11-5 | Fenway Park (15-6) | 25-18 | |
| » Starters: Bob Feller vs Joe Dobson | Third | 4½ out |
| Saturday, June 3 |
| » Defeated Indians (20-19), 11-9 | Fenway Park (16-6) | 26-18 | Won 2 |
| » Starters: Mike Garcia vs Mel Parnell | Third | 5 out |
| Sunday, June 4 |
| » Defeated White Sox (14-27), 17-7 | Fenway Park (17-6) | 27-18 | Won 3 |
| » Starters: Mickey Haefner vs Chuck Stobbs | Third | 5 out |
| Monday, June 5 |
| » Defeated White Sox (14-28), 12-0 | Fenway Park (18-6) | 28-18 | Won 4 |
| » Starters: Billy Pierce vs Ellis Kinder | Third | 4 out |
| Tuesday, June 6 |
| » Lost to White Sox (15-28), 8-4 | Fenway Park (18-7) | 28-19 | |
| » Starters: Ken Holcombe vs Mel Parnell | Third | 3½ out |
| Wednesday, June 7 |
| » Defeated Browns (13-27), 20-4 | Fenway Park (19-7) | 29-19 | |
| » Starters: Fritz Dorish vs Joe Dobson | Third | 4 out |
| Thursday, June 8 |
| » Defeated Browns (13-28), 29-4 | Fenway Park (20-7) | 30-19 | Won 2 |
| » Starters: Cliff Fannin vs Chuck Stobbs | Third | 4 out |
| Friday, June 9 |
| » Lost to Browns (14-28), 12-7 | Fenway Park (20-8) | 30-20 | |
| » Starters: Ned Garver vs Mickey McDermott | Third | 4 out |
| Saturday, June 10 |
| » Lost to Tigers (30-14), 18-8 | Fenway Park (20-9) | 30-21 | Lost 2 |
| » Starters: Dizzy Trout vs Ellis Kinder | Third | 3½ out |
| Sunday, June 11 |
| » Lost to Tigers (31-14), 6-2 | Fenway Park (20-10) | 30-22 | Lost 3 |
| » Starters: Hal Newhouser vs Joe Dobson | Third | 5½ out |
| » Lost to Tigers (32-14), 9-6 | Fenway Park (20-11) | 30-23 | Lost 4 |
| » Starters: Fred Hutchinson vs Mel Parnell | Third | 5½ out |
| Tuesday, June 13 |
| » Defeated Indians (25-24), 8-1 | Cleveland Stadium (1-2) | 31-23 | |
| » Starters: Chuck Stobbs vs Bob Feller | Third | 5½ out |
| Wednesday, June 14 |
| » Lost to Indians (26-24), 7-3 | Cleveland Stadium (1-3) | 31-24 | |
| » Starters: Ellis Kinder vs Mike Garcia | Third | 5½ out |
| Thursday, June 15 |
| » Lost to Indians (27-24), 3-1 | Cleveland Stadium (1-4) | 31-25 | Lost 2 |
| » Starters: Walt Masterson vs Bob Lemon | Third | 6½ out |
| Friday, June 16 |
| » Lost to Tigers (35-15), 4-1 | Tiger Stadium (2-2) | 31-26 | Lost 3 |
| » Starters: Joe Dobson vs Hal Newhouser | Third | 7½ out |
| Saturday, June 17 |
| » Lost to Tigers (36-15), 2-1 | Tiger Stadium (2-3) | 31-27 | Lost 4 |
| » Starters: Mel Parnell vs Ted Gray | Fourth | 8½ out |
| Sunday, June 18 |
| » Lost to Tigers (37-15), 10-2 | Tiger Stadium (2-4) | 31-28 | Lost 5 |
| » Starters: Chuck Stobbs vs Art Houtteman | Fourth | 9½ out |
| Tuesday, June 20 |
| » Defeated White Sox (23-33), 5-3 | Comiskey Park I (2-2) | 32-28 | |
| » Manager: Steve O'Neill |
| » Starters: Ellis Kinder vs Bill Wight | Fourth | 8½ out |
| Wednesday, June 21 |
| » Lost to White Sox (24-33), 3-1 | Comiskey Park I (2-3) | 32-29 | |
| » Starters: Joe Dobson vs Billy Pierce | Fourth | 8½ out |
| Thursday, June 22 |
| » Lost to White Sox (25-33), 4-2 | Comiskey Park I (2-4) | 32-30 | Lost 2 |
| » Starters: Mel Parnell vs Rae Scarborough | Fourth | 8½ out |
| Friday, June 23 |
| » Defeated Browns (20-37), 12-9 | Sportsman's Park III (3-0) | 33-30 | |
| » Starters: Chuck Stobbs vs Fritz Dorish | Fourth | 8½ out |
| Saturday, June 24 |
| » Defeated Browns (20-38), 12-3 | Sportsman's Park III (4-0) | 34-30 | Won 2 |
| » Starters: Ellis Kinder vs Cliff Fannin | Fourth | 8½ out |
| Sunday, June 25 |
| » Defeated Browns (20-39), 11-5 | Sportsman's Park III (5-0) | 35-30 | Won 3 |
| » Starters: Joe Dobson vs Ned Garver | Fourth | 7½ out |
| » Defeated Browns (20-40), 8-2 | Sportsman's Park III (6-0) | 36-30 | Won 4 |
| » Starters: Walt Masterson vs Stubby Overmire | Fourth | 7½ out |
| Tuesday, June 27 |
| » Defeated Athletics (22-42), 7-5 | Shibe Park (3-2) | 37-30 | Won 5 |
| » Starters: Mel Parnell vs Bobby Shantz | Fourth | 8 out |
| Wednesday, June 28 |
| » Defeated Athletics (22-43), 6-2 | Shibe Park (4-2) | 38-30 | Won 6 |
| » Starters: Ellis Kinder vs Lou Brissie | Fourth | 8 out |
| Thursday, June 29 |
| » Defeated Athletics (22-44), 22-14 | Shibe Park (5-2) | 39-30 | Won 7 |
| » Starters: Chuck Stobbs vs Bob Hooper | Fourth | 7 out |
| Friday, June 30 |
| » Lost to Yankees (41-26), 9-6 | Fenway Park (20-12) | 39-31 | |
| » Starters: Vic Raschi vs Joe Dobson | Fourth | 6½ out |
| » Defeated Yankees (41-27), 10-2 | Fenway Park (21-12) | 40-31 | |
| » Starters: Eddie Lopat vs Walt Masterson | Fourth | 6½ out |
| Saturday, July 1 |
| » Defeated Yankees (41-28), 13-4 | Fenway Park (22-12) | 41-31 | Won 2 |
| » Starters: Tommy Byrne vs Mel Parnell | Fourth | 5½ out |
| Sunday, July 2 |
| » Lost to Yankees (42-28), 15-9 | Fenway Park (22-13) | 41-32 | |
| » Starters: Allie Reynolds vs Ellis Kinder | Fourth | 6 out |
| Wednesday, July 5 |
| » Lost to Senators (33-39), 9-7 | Fenway Park (22-14) | 41-33 | Lost 2 |
| » Starters: Sandy Consuegra vs Chuck Stobbs | Fourth | 7½ out |
| Friday, July 7 |
| » Lost to Yankees (46-29), 5-2 | Yankee Stadium (1-4) | 41-34 | Lost 3 |
| » Starters: Dick Littlefield vs Allie Reynolds | Fourth | 8½ out |
| » Major-league debuts: Dick Littlefield and Willard Nixon (Red Sox) |
| Saturday, July 8 |
| » Defeated Yankees (46-30), 4-2 | Yankee Stadium (2-4) | 42-34 | |
| » Starters: Walt Masterson vs Vic Raschi | Fourth | 8½ out |
| Sunday, July 9 |
| » Lost to Yankees (47-30), 3-1 | Yankee Stadium (2-5) | 42-35 | |
| » Starters: Joe Dobson vs Eddie Lopat | Fourth | 8 out |
| Thursday, July 13 |
| » Defeated White Sox (34-46), 8-7 | Fenway Park (23-14) | 43-35 | |
| » Starters: Rae Scarborough vs Willard Nixon | Fourth | 8 out |
| Friday, July 14 |
| » Defeated White Sox (34-47), 13-1 | Fenway Park (24-14) | 44-35 | Won 2 |
| » Starters: Ken Holcombe vs Ellis Kinder | Fourth | 8 out |
| Saturday, July 15 |
| » Lost to White Sox (35-47), 7-3 | Fenway Park (24-15) | 44-36 | |
| » Starters: Lou Kretlow vs Dick Littlefield | Fourth | 8½ out |
| Sunday, July 16 |
| » Defeated Indians (47-34), 13-10 | Fenway Park (25-15) | 45-36 | |
| » Starters: Mike Garcia vs Mel Parnell | Fourth | 8½ out |
| » Lost to Indians (48-34), 8-4 | Fenway Park (25-16) | 45-37 | |
| » Starters: Steve Gromek vs Walt Masterson | Fourth | 8½ out |
| Monday, July 17 |
| » Lost to Indians (49-34), 11-6 | Fenway Park (25-17) | 45-38 | Lost 2 |
| » Starters: Early Wynn vs Joe Dobson | Fourth | 9½ out |
| » Defeated Indians (49-35), 7-5 | Fenway Park (26-17) | 46-38 | |
| » Starters: Mike Garcia vs Mickey McDermott | Fourth | 9½ out |
| Tuesday, July 18 |
| » Defeated Tigers (54-28), 12-9 | Fenway Park (27-17) | 47-38 | Won 2 |
| » Starters: Fred Hutchinson vs Ellis Kinder | Fourth | 8½ out |
| Wednesday, July 19 |
| » Lost to Tigers (55-28), 9-5 | Fenway Park (27-18) | 47-39 | |
| » Starters: Dizzy Trout vs Willard Nixon | Fourth | 9½ out |
| Thursday, July 20 |
| » Defeated Tigers (55-29), 6-5 | Fenway Park (28-18) | 48-39 | |
| » Starters: Art Houtteman vs Walt Masterson | Fourth | 8½ out |
| Friday, July 21 |
| » Defeated Browns (30-56), 7-4 | Fenway Park (29-18) | 49-39 | Won 2 |
| » Starters: Fritz Dorish vs Joe Dobson | Fourth | 7½ out |
| Saturday, July 22 |
| » Defeated Browns (30-57), 11-2 | Fenway Park (30-18) | 50-39 | Won 3 |
| » Starters: Dick Starr vs Mickey McDermott | Fourth | 6½ out |
| Sunday, July 23 |
| » Defeated Browns (30-58), 6-2 | Fenway Park (31-18) | 51-39 | Won 4 |
| » Starters: Don Johnson vs Ellis Kinder | Fourth | 6½ out |
| Tuesday, July 25 |
| » Defeated Tigers (56-32), 7-6 | Tiger Stadium (3-4) | 52-39 | Won 5 |
| » Starters: Willard Nixon vs Ted Gray | Fourth | 5½ out |
| Wednesday, July 26 |
| » Defeated Tigers (56-33), 1-0 | Tiger Stadium (4-4) | 53-39 | Won 6 |
| » Starters: Mel Parnell vs Art Houtteman | Fourth | 4½ out |
| Thursday, July 27 |
| » Lost to Tigers (57-33), 5-1 | Tiger Stadium (4-5) | 53-40 | |
| » Starters: Ellis Kinder vs Dizzy Trout | Fourth | 5½ out |
| » Major-league debuts: Jim McDonald (Red Sox) |
| Friday, July 28 |
| » Lost to Indians (57-37), 13-1 | Cleveland Stadium (1-5) | 53-41 | Lost 2 |
| » Starters: Mickey McDermott vs Early Wynn | Fourth | 5½ out |
| Saturday, July 29 |
| » Lost to Indians (58-37), 4-1 | Cleveland Stadium (1-6) | 53-42 | Lost 3 |
| » Starters: Chuck Stobbs vs Bob Lemon | Fourth | 6½ out |
| Sunday, July 30 |
| » Lost to Indians (59-37), 6-5 | Cleveland Stadium (1-7) | 53-43 | Lost 4 |
| » Starters: Walt Masterson vs Bob Feller | Fourth | 7 out |
| » Defeated Indians (59-38), 6-3 | Cleveland Stadium (2-7) | 54-43 | |
| » Starters: Willard Nixon vs Sam Zoldak | Fourth | 7 out |
| Tuesday, August 1 |
| » Defeated Browns (34-62), 7-3 | Sportsman's Park III (7-0) | 55-43 | Won 2 |
| » Starters: Mel Parnell vs Cuddles Marshall | Fourth | 7 out |
| Wednesday, August 2 |
| » Defeated Browns (34-63), 9-8 | Sportsman's Park III (8-0) | 56-43 | Won 3 |
| » Starters: Mickey McDermott vs Al Widmar | Fourth | 7 out |
| Friday, August 4 |
| » Lost to White Sox (41-61), 3-2 | Comiskey Park I (2-5) | 56-44 | |
| » Starters: Willard Nixon vs Ken Holcombe | Fourth | 7½ out |
| Saturday, August 5 |
| » Defeated White Sox (41-62), 12-7 | Comiskey Park I (3-5) | 57-44 | |
| » Starters: Walt Masterson vs Bob Cain | Fourth | 7½ out |
| Sunday, August 6 |
| » Defeated White Sox (41-63), 9-2 | Comiskey Park I (4-5) | 58-44 | Won 2 |
| » Starters: Ellis Kinder vs Billy Pierce | Fourth | 7 out |
| » Defeated White Sox (41-64), 4-3 | Comiskey Park I (5-5) | 59-44 | Won 3 |
| » Starters: Joe Dobson vs Howie Judson | Fourth | 7 out |
| Tuesday, August 8 |
| » Defeated Yankees (62-40), 7-4 | Yankee Stadium (3-5) | 60-44 | Won 4 |
| » Starters: Mel Parnell vs Allie Reynolds | Third | 6 out |
| Wednesday, August 9 |
| » Lost to Yankees (63-40), 2-1 | Yankee Stadium (3-6) | 60-45 | |
| » Starters: Chuck Stobbs vs Vic Raschi | Fourth | 7 out |
| Thursday, August 10 |
| » Lost to Senators (46-55), 11-2 | Griffith Stadium (2-3) | 60-46 | Lost 2 |
| » Starters: Willard Nixon vs Bob Kuzava | Fourth | 7½ out |
| » Defeated Senators (46-56), 4-3 | Griffith Stadium (3-3) | 61-46 | |
| » Starters: Walt Masterson vs Gene Bearden | Fourth | 7½ out |
| Friday, August 11 |
| » Lost to Senators (47-56), 5-2 | Griffith Stadium (3-4) | 61-47 | |
| » Starters: Ellis Kinder vs Sandy Consuegra | Fourth | 8 out |
| Saturday, August 12 |
| » Defeated Senators (47-57), 10-1 | Griffith Stadium (4-4) | 62-47 | |
| » Starters: Joe Dobson vs Sid Hudson | Fourth | 7½ out |
| Sunday, August 13 |
| » Lost to Senators (48-57), 6-5 | Griffith Stadium (4-5) | 62-48 | |
| » Starters: Mickey McDermott vs Al Sima | Fourth | 8 out |
| Tuesday, August 15 |
| » Defeated Athletics (40-69), 8-3 | Fenway Park (32-18) | 63-48 | |
| » Starters: Hank Wyse vs Mel Parnell | Fourth | 7 out |
| » Defeated Athletics (40-70), 9-4 | Fenway Park (33-18) | 64-48 | Won 2 |
| » Starters: Alex Kellner vs Willard Nixon | Fourth | 7 out |
| Wednesday, August 16 |
| » Defeated Athletics (40-71), 11-3 | Fenway Park (34-18) | 65-48 | Won 3 |
| » Starters: Joe Coleman vs Chuck Stobbs | Fourth | 6½ out |
| » Defeated Athletics (40-72), 12-7 | Fenway Park (35-18) | 66-48 | Won 4 |
| » Starters: Bob Hooper vs Walt Masterson | Fourth | 6½ out |
| Thursday, August 17 |
| » Defeated Athletics (40-73), 10-6 | Fenway Park (36-18) | 67-48 | Won 5 |
| » Starters: Joe Murray vs Ellis Kinder | Fourth | 6½ out |
| » Major-league debuts: Joe Murray (Athletics) |
| Friday, August 18 |
| » Defeated Senators (50-60), 7-6 | Fenway Park (37-18) | 68-48 | Won 6 |
| » Starters: Al Sima vs Joe Dobson | Fourth | 6 out |
| Saturday, August 19 |
| » Defeated Senators (50-61), 5-4 | Fenway Park (38-18) | 69-48 | Won 7 |
| » Starters: Connie Marrero vs Mel Parnell | Fourth | 6 out |
| Tuesday, August 22 |
| » Defeated Browns (39-74), 9-5 | Fenway Park (39-18) | 70-48 | Won 8 |
| » Starters: Don Johnson vs Willard Nixon | Fourth | 5½ out |
| Wednesday, August 23 |
| » Defeated Browns (39-75), 9-5 | Fenway Park (40-18) | 71-48 | Won 9 |
| » Starters: Dick Starr vs Chuck Stobbs | Fourth | 4½ out |
| Thursday, August 24 |
| » Defeated Browns (39-76), 6-2 | Fenway Park (41-18) | 72-48 | Won 10 |
| » Starters: Ned Garver vs Walt Masterson | Fourth | 4½ out |
| Friday, August 25 |
| » Defeated Tigers (74-42), 6-2 | Fenway Park (42-18) | 73-48 | Won 11 |
| » Starters: Dizzy Trout vs Mel Parnell | Fourth | 3½ out |
| Saturday, August 26 |
| » Lost to Tigers (75-42), 8-6 | Fenway Park (42-19) | 73-49 | |
| » Starters: Hal White vs Joe Dobson | Fourth | 4½ out |
| Sunday, August 27 |
| » Defeated Indians (76-47), 11-9 | Fenway Park (43-19) | 74-49 | |
| » Starters: Bob Feller vs Willard Nixon | Fourth | 4 out |
| Monday, August 28 |
| » Defeated Indians (76-48), 15-14 | Fenway Park (44-19) | 75-49 | Won 2 |
| » Starters: Bob Lemon vs Mickey McDermott | Fourth | 3 out |
| Tuesday, August 29 |
| » Defeated White Sox (50-75), 13-6 | Fenway Park (45-19) | 76-49 | Won 3 |
| » Starters: Randy Gumpert vs Mel Parnell | Third | 2 out |
| Wednesday, August 30 |
| » Defeated White Sox (50-76), 6-1 | Fenway Park (46-19) | 77-49 | Won 4 |
| » Starters: Ken Holcombe vs Joe Dobson | Third | 2½ out |
| Thursday, August 31 |
| » Defeated White Sox (50-77), 4-3 | Fenway Park (47-19) | 78-49 | Won 5 |
| » Starters: Billy Pierce vs Walt Masterson | Third | 2½ out |
| » Major-league debuts: Fred Hatfield (Red Sox) |
| Friday, September 1 |
| » Lost to Athletics (45-84), 4-2 | Shibe Park (5-3) | 78-50 | |
| » Starters: Chuck Stobbs vs Bobby Shantz | Third | 3½ out |
| Saturday, September 2 |
| » Defeated Athletics (45-85), 9-3 | Shibe Park (6-3) | 79-50 | |
| » Starters: Mel Parnell vs Carl Scheib | Third | 3½ out |
| Monday, September 4 |
| » Defeated Senators (56-71), 5-4 | Griffith Stadium (5-5) | 80-50 | Won 2 |
| » Starters: Joe Dobson vs Sid Hudson | Third | 3½ out |
| » Lost to Senators (57-71), 5-3 | Griffith Stadium (5-6) | 80-51 | |
| » Starters: Willard Nixon vs Bob Kuzava | Third | 3½ out |
| Wednesday, September 6 |
| » Defeated Yankees (83-48), 11-2 | Fenway Park (48-19) | 81-51 | |
| » Starters: Eddie Lopat vs Mel Parnell | Third | 2½ out |
| Thursday, September 7 |
| » Defeated Yankees (83-49), 10-8 | Fenway Park (49-19) | 82-51 | Won 2 |
| » Starters: Allie Reynolds vs Ellis Kinder | Third | 1½ out |
| » Major-league debuts: Jimmy Piersall (Red Sox) |
| Saturday, September 9 |
| » Defeated Athletics (47-89), 8-3 | Fenway Park (50-19) | 83-51 | Won 3 |
| » Starters: Lou Brissie vs Willard Nixon | Third | 1½ out |
| » Defeated Athletics (47-90), 11-3 | Fenway Park (51-19) | 84-51 | Won 4 |
| » Starters: Alex Kellner vs Walt Masterson | Third | 1½ out |
| Sunday, September 10 |
| » Defeated Athletics (47-91), 6-2 | Fenway Park (52-19) | 85-51 | Won 5 |
| » Starters: Hank Wyse vs Chuck Stobbs | Third | 1 out |
| Tuesday, September 12 |
| » Defeated White Sox (53-86), 2-1 | Comiskey Park I (6-5) | 86-51 | Won 6 |
| » Starters: Mel Parnell vs Bill Wight | Third | 1 out |
| Thursday, September 14 |
| » Lost to Browns (52-86), 6-3 | Sportsman's Park III (8-1) | 86-52 | |
| » Starters: Willard Nixon vs Dick Starr | Third | 2 out |
| Friday, September 15 |
| » Defeated Browns (52-87), 12-9 | Sportsman's Park III (9-1) | 87-52 | |
| » Starters: Joe Dobson vs Don Johnson | Third | 1½ out |
| Saturday, September 16 |
| » Lost to Browns (53-87), 5-2 | Sportsman's Park III (9-2) | 87-53 | |
| » Starters: Walt Masterson vs Cliff Fannin | Third | 2 out |
| Sunday, September 17 |
| » Defeated Tigers (88-52), 3-2 | Tiger Stadium (5-5) | 88-53 | |
| » Starters: Mel Parnell vs Fred Hutchinson | Third | 1½ out |
| Monday, September 18 |
| » Defeated Tigers (88-53), 3-2 | Tiger Stadium (6-5) | 89-53 | Won 2 |
| » Starters: Willard Nixon vs Hal Newhouser | Second | 1 out |
| Wednesday, September 20 |
| » Lost to Indians (84-61), 6-3 | Cleveland Stadium (2-8) | 89-54 | |
| » Starters: Chuck Stobbs vs Bob Lemon | Third | 2 out |
| » Lost to Indians (85-61), 7-1 | Cleveland Stadium (2-9) | 89-55 | Lost 2 |
| » Starters: Joe Dobson vs Early Wynn | Third | 2 out |
| Saturday, September 23 |
| » Lost to Yankees (92-53), 8-0 | Yankee Stadium (3-7) | 89-56 | Lost 3 |
| » Starters: Mel Parnell vs Eddie Lopat | Third | 3 out |
| Sunday, September 24 |
| » Lost to Yankees (93-53), 9-5 | Yankee Stadium (3-8) | 89-57 | Lost 4 |
| » Starters: Willard Nixon vs Vic Raschi | Third | 4 out |
| Monday, September 25 |
| » Defeated Athletics (50-100), 8-0 | Shibe Park (7-3) | 90-57 | |
| » Starters: Mel Parnell vs Alex Kellner | Third | 4 out |
| » Defeated Athletics (50-101), 3-0 | Shibe Park (8-3) | 91-57 | Won 2 |
| » Starters: Harry Taylor vs Bobby Shantz | Third | 4 out |
| Wednesday, September 27 |
| » Lost to Senators (66-84), 2-0 | Fenway Park (52-20) | 91-58 | |
| » Starters: Connie Marrero vs Joe Dobson | Third | 4½ out |
| » Lost to Senators (67-84), 6-3 | Fenway Park (52-21) | 91-59 | Lost 2 |
| » Starters: Gene Bearden vs Willard Nixon | Third | 4½ out |
| Thursday, September 28 |
| » Defeated Senators (67-85), 4-3 | Fenway Park (53-21) | 92-59 | |
| » Starters: Carlos Pascual vs Chuck Stobbs | Third | 4½ out |
| Friday, September 29 |
| » Defeated Senators (67-86), 7-6 | Fenway Park (54-21) | 93-59 | Won 2 |
| » Starters: Bob Kuzava vs Walt Masterson | Third | 4 out |
| Saturday, September 30 |
| » Lost to Yankees (98-55), 6-5 | Fenway Park (54-22) | 93-60 | |
| » Starters: Tommy Byrne vs Mel Parnell | Third | 5 out |
| Sunday, October 1 |
| » Defeated Yankees (98-56), 7-3 | Fenway Park (55-22) | 94-60 | |
| » Starters: Ernie Nevel vs Harry Taylor | Third | 4 out |
| Friday, October 13 |
| Future Red Sox Dick Pole is born in Trout Creek, MI. |
| Wednesday, November 29 |
| Future Red Sox Mike Easler is born in Cleveland, OH. |
Game information provided by Retrosheet (www.retrosheet.org) |