| Tuesday, January 17 |
| Former Pirate Jewel Ens dies in Syracuse, NY at the age of 61. |
| Saturday, February 11 |
| Former Pirate Kiki Cuyler dies in Ann Arbor, MI at the age of 52. |
| Saturday, February 18 |
| Future Pirate Bruce Kison is born in Pasco, WA. |
| Tuesday, April 18 |
| » Lost to Cardinals (1-0), 4-2 | Sportsman's Park III (0-1) | 0-1 | |
| » Starters: Bob Chesnes vs Gerry Staley | Second | 1 out |
| Wednesday, April 19 |
| » Defeated Cardinals (1-1), 4-3 | Sportsman's Park III (1-1) | 1-1 | |
| » Starters: Cliff Chambers vs Red Munger | Third | 1 out |
| Thursday, April 20 |
| » Defeated Cardinals (1-2), 8-4 | Sportsman's Park III (2-1) | 2-1 | Won 2 |
| » Starters: Murry Dickson vs Howie Pollet | Third | ½ out |
| » Major-league debuts: Tom Poholsky (Cardinals) |
| Friday, April 21 |
| » Defeated Reds (0-2), 7-5 | Forbes Field (1-0) | 3-1 | Won 3 |
| » Starters: Herm Wehmeier vs Bill Werle | Second | 1 out |
| Saturday, April 22 |
| » Defeated Reds (0-3), 9-2 | Forbes Field (2-0) | 4-1 | Won 4 |
| » Starters: Johnny Hetki vs Bob Chesnes | Second | 1 out |
| » Major-league debuts: Dale Coogan (Pirates) |
| Sunday, April 23 |
| » Defeated Reds (0-4), 5-3 | Forbes Field (3-0) | 5-1 | Won 5 |
| » Starters: Frank Smith vs Cliff Chambers | Second | 1½ out |
| » Major-league debuts: Joe Adcock (Reds) |
| Former Pirate Bill Hallman dies in Philadelphia, PA at the age of 75. |
| Thursday, April 27 |
| » Lost to Cardinals (4-4), 5-2 | Forbes Field (3-1) | 5-2 | |
| » Starters: Red Munger vs Murry Dickson | Third | 2 out |
| Friday, April 28 |
| » Defeated Cardinals (4-5), 4-3 | Forbes Field (4-1) | 6-2 | |
| » Starters: Gerry Staley vs Bill Werle | Second | ½ out |
| Saturday, April 29 |
| » Lost to Reds (2-6), 14-6 | Crosley Field (0-1) | 6-3 | |
| » Starters: Bob Chesnes vs Frank Smith | Third | 1 out |
| Sunday, April 30 |
| » Lost to Reds (3-6), 4-2 | Crosley Field (0-2) | 6-4 | Lost 2 |
| » Starters: Cliff Chambers vs Howie Fox | Third | 2 out |
| » Lost to Reds (4-6), 2-1 | Crosley Field (0-3) | 6-5 | Lost 3 |
| » Starters: Mel Queen vs Ewell Blackwell | Third | 2 out |
| Tuesday, May 2 |
| » Defeated Braves (6-7), 6-1 | Forbes Field (5-1) | 7-5 | |
| » Starters: Warren Spahn vs Murry Dickson | Third | 1½ out |
| Wednesday, May 3 |
| » Lost to Braves (7-7), 15-4 | Forbes Field (5-2) | 7-6 | |
| » Starters: Johnny Sain vs Bill Werle | Third | 1½ out |
| Thursday, May 4 |
| » Defeated Giants (2-7), 3-1 | Forbes Field (6-2) | 8-6 | |
| » Starters: Larry Jansen vs Cliff Chambers | Second | 1½ out |
| Friday, May 5 |
| » Defeated Giants (2-8), 5-4 | Forbes Field (7-2) | 9-6 | Won 2 |
| » Starters: Sheldon Jones vs Mel Queen | Second | ½ out |
| » Major-league debuts: Tookie Gilbert (Giants) |
| Saturday, May 6 |
| » Lost to Giants (3-8), 9-8 | Forbes Field (7-3) | 9-7 | |
| » Starters: Clint Hartung vs Bob Chesnes | Fourth | ½ out |
| » Major-league debuts: Bill Macdonald (Pirates) |
| Sunday, May 7 |
| » Lost to Dodgers (10-6), 3-2 | Forbes Field (7-4) | 9-8 | Lost 2 |
| » Starters: Jack Banta vs Murry Dickson | Fourth | 1½ out |
| Monday, May 8 |
| » Lost to Dodgers (11-6), 7-5 | Forbes Field (7-5) | 9-9 | Lost 3 |
| » Starters: Bud Podbielan vs Cliff Chambers | Sixth | 2½ out |
| Tuesday, May 9 |
| » Defeated Dodgers (11-7), 10-5 | Forbes Field (8-5) | 10-9 | |
| » Starters: Ralph Branca vs Mel Queen | Fifth | 1½ out |
| Thursday, May 11 |
| » Lost to Phillies (13-8), 3-2 | Forbes Field (8-6) | 10-10 | |
| » Starters: Robin Roberts vs Murry Dickson | Fifth | 2½ out |
| Friday, May 12 |
| » Lost to Cubs (9-7), 6-3 | Wrigley Field (0-1) | 10-11 | Lost 2 |
| » Starters: Hal Gregg vs Bob Rush | Sixth | 3 out |
| Saturday, May 13 |
| » Lost to Cubs (10-7), 4-3 | Wrigley Field (0-2) | 10-12 | Lost 3 |
| » Starters: Cliff Chambers vs Frank Hiller | Sixth | 4 out |
| Sunday, May 14 |
| » Defeated Cubs (10-8), 6-5 | Wrigley Field (1-2) | 11-12 | |
| » Starters: Junior Walsh vs Johnny Schmitz | Sixth | 3 out |
| » Defeated Cubs (10-9), 16-9 | Wrigley Field (2-2) | 12-12 | Won 2 |
| » Starters: Mel Queen vs Doyle Lade | Sixth | 3 out |
| Tuesday, May 16 |
| » Lost to Braves (13-11), 3-0 | Braves Field (0-1) | 12-13 | |
| » Starters: Murry Dickson vs Johnny Sain | Sixth | 4 out |
| Wednesday, May 17 |
| » Defeated Braves (13-12), 4-1 | Braves Field (1-1) | 13-13 | |
| » Starters: Cliff Chambers vs Vern Bickford | Sixth | 4 out |
| Thursday, May 18 |
| » Major-league debuts: Billy Loes (Dodgers) |
| Saturday, May 20 |
| » Lost to Dodgers (16-9), 3-2 | Ebbets Field (0-1) | 13-14 | |
| » Starters: Mel Queen vs Dan Bankhead | Sixth | 5 out |
| » Lost to Dodgers (17-9), 4-3 | Ebbets Field (0-2) | 13-15 | Lost 2 |
| » Starters: Murry Dickson vs Bud Podbielan | Sixth | 5 out |
| Sunday, May 21 |
| » Defeated Giants (10-13), 4-2 | Polo Grounds V (1-0) | 14-15 | |
| » Starters: Bob Chesnes vs Larry Jansen | Fourth | 3½ out |
| » Defeated Giants (10-14), 8-6 | Polo Grounds V (2-0) | 15-15 | Won 2 |
| » Starters: Cliff Chambers vs Sheldon Jones | Fourth | 3½ out |
| Tuesday, May 23 |
| » Defeated Phillies (17-12), 6-0 | Shibe Park (1-0) | 16-15 | Won 3 |
| » Starters: Bill Macdonald vs Russ Meyer | Fifth | 3 out |
| Wednesday, May 24 |
| » Lost to Phillies (18-12), 6-3 | Shibe Park (1-1) | 16-16 | |
| » Starters: Murry Dickson vs Bubba Church | Fifth | 4 out |
| Thursday, May 25 |
| » Lost to Phillies (19-12), 3-0 | Shibe Park (1-2) | 16-17 | Lost 2 |
| » Starters: Cliff Chambers vs Bob Miller | Fifth | 5 out |
| Friday, May 26 |
| » Lost to Cubs (14-15), 4-0 | Forbes Field (8-7) | 16-18 | Lost 3 |
| » Starters: Frank Hiller vs Mel Queen | Sixth | 6 out |
| Saturday, May 27 |
| » Lost to Cubs (15-15), 7-5 | Forbes Field (8-8) | 16-19 | Lost 4 |
| » Starters: Paul Minner vs Bob Chesnes | Sixth | 6½ out |
| Sunday, May 28 |
| » Lost to Cubs (16-15), 6-0 | Forbes Field (8-9) | 16-20 | Lost 5 |
| » Starters: Johnny Schmitz vs Murry Dickson | Sixth | 7½ out |
| » Lost to Cubs (17-15), 5-1 | Forbes Field (8-10) | 16-21 | Lost 6 |
| » Starters: Bob Rush vs Vic Lombardi | Sixth | 7½ out |
| Tuesday, May 30 |
| » Lost to Cardinals (21-14), 17-13 | Forbes Field (8-11) | 16-22 | Lost 7 |
| » Starters: Cloyd Boyer vs Bill Macdonald | Sixth | 8½ out |
| » Lost to Cardinals (22-14), 8-5 | Forbes Field (8-12) | 16-23 | Lost 8 |
| » Starters: Red Munger vs Cliff Chambers | Sixth | 8½ out |
| » Major-league debuts: Gus Bell (Pirates) |
| Thursday, June 1 |
| » Lost to Braves (20-16), 14-2 | Forbes Field (8-13) | 16-24 | Lost 9 |
| » Starters: Vern Bickford vs Mel Queen | Fifth | 8½ out |
| Friday, June 2 |
| » Defeated Braves (20-17), 5-4 | Forbes Field (9-13) | 17-24 | |
| » Starters: Warren Spahn vs Bill Macdonald | Sixth | 8½ out |
| Saturday, June 3 |
| » Lost to Braves (21-17), 10-6 | Forbes Field (9-14) | 17-25 | |
| » Starters: Johnny Sain vs Murry Dickson | Sixth | 9 out |
| Sunday, June 4 |
| » Lost to Giants (15-21), 4-3 | Forbes Field (9-15) | 17-26 | Lost 2 |
| » Starters: Larry Jansen vs Cliff Chambers | Sixth | 9 out |
| Monday, June 5 |
| » Lost to Giants (16-21), 5-4 | Forbes Field (9-16) | 17-27 | Lost 3 |
| » Starters: Clint Hartung vs Murry Dickson | Seventh | 10 out |
| Tuesday, June 6 |
| » Lost to Giants (17-21), 10-4 | Forbes Field (9-17) | 17-28 | Lost 4 |
| » Starters: Jack Kramer vs Mel Queen | Sixth | 10 out |
| Wednesday, June 7 |
| » Lost to Dodgers (26-16), 9-0 | Forbes Field (9-18) | 17-29 | Lost 5 |
| » Starters: Don Newcombe vs Bill Macdonald | Seventh | 11 out |
| Thursday, June 8 |
| » Defeated Dodgers (26-17), 4-3 | Forbes Field (10-18) | 18-29 | |
| » Starters: Ralph Branca vs Cliff Chambers | Sixth | 10 out |
| Friday, June 9 |
| » Lost to Dodgers (27-17), 9-7 | Forbes Field (10-19) | 18-30 | |
| » Starters: Jack Banta vs Murry Dickson | Fifth | 11 out |
| Sunday, June 11 |
| » Lost to Phillies (27-18), 7-6 | Forbes Field (10-20) | 18-31 | Lost 2 |
| » Starters: Robin Roberts vs Vern Law | Sixth | 12½ out |
| » Defeated Phillies (27-19), 5-4 | Forbes Field (11-20) | 19-31 | |
| » Starters: Bob Miller vs Bill Macdonald | Sixth | 12½ out |
| Tuesday, June 13 |
| » Lost to Giants (21-24), 7-0 | Polo Grounds V (2-1) | 19-32 | |
| » Starters: Cliff Chambers vs Larry Jansen | Sixth | 13½ out |
| Friday, June 16 |
| » Lost to Braves (28-23), 6-5 | Braves Field (1-2) | 19-33 | Lost 2 |
| » Starters: Vern Law vs Johnny Sain | Seventh | 14 out |
| Saturday, June 17 |
| » Lost to Braves (29-23), 15-6 | Braves Field (1-3) | 19-34 | Lost 3 |
| » Starters: Hank Borowy vs Ernie Johnson | Seventh | 14 out |
| Sunday, June 18 |
| » Lost to Braves (30-23), 8-6 | Braves Field (1-4) | 19-35 | Lost 4 |
| » Starters: Frank Papish vs Vern Bickford | Seventh | 14 out |
| » Tied Braves, 8-8 | Braves Field (1-4) | 19-35 | |
| » Starters: Cliff Chambers vs Dick Donovan | Seventh | 14 out |
| Monday, June 19 |
| » Defeated Braves (30-24), 1-0 | Braves Field (2-4) | 20-35 | |
| » Starters: Cliff Chambers vs Warren Spahn | Sixth | 13½ out |
| Future Pirate Fernando Gonzalez is born in Arecibo, P.R. |
| Tuesday, June 20 |
| » Lost to Phillies (31-21), 7-3 | Shibe Park (1-3) | 20-36 | |
| » Starters: Vern Law vs Russ Meyer | Sixth | 14½ out |
| Wednesday, June 21 |
| » Defeated Phillies (31-22), 5-3 | Shibe Park (2-3) | 21-36 | |
| » Starters: Bill Macdonald vs Robin Roberts | Sixth | 13½ out |
| Thursday, June 22 |
| » Lost to Phillies (32-22), 7-4 | Shibe Park (2-4) | 21-37 | |
| » Starters: Hank Borowy vs Bob Miller | Sixth | 13½ out |
| Friday, June 23 |
| » Lost to Dodgers (34-22), 15-3 | Ebbets Field (0-3) | 21-38 | Lost 2 |
| » Starters: Murry Dickson vs Bud Podbielan | Seventh | 14½ out |
| Saturday, June 24 |
| » Game at Ebbets Field interrupted in the 8th inning with the score of Dodgers 19, Pirates 12. Completed on August 01. |
| Sunday, June 25 |
| » Defeated Dodgers (34-23), 16-11 | Ebbets Field (1-3) | 22-38 | |
| » Starters: Vern Law vs Don Newcombe | Seventh | 13½ out |
| Tuesday, June 27 |
| » Lost to Reds (20-40), 8-3 | Forbes Field (11-21) | 22-39 | |
| » Starters: Herm Wehmeier vs Bill Macdonald | Seventh | 14½ out |
| Wednesday, June 28 |
| » Defeated Reds (20-41), 6-5 | Forbes Field (12-21) | 23-39 | |
| » Starters: Howie Fox vs Bill Werle | Seventh | 13½ out |
| Friday, June 30 |
| » Lost to Cardinals (37-27), 9-4 | Sportsman's Park III (2-2) | 23-40 | |
| » Starters: Cliff Chambers vs Gerry Staley | Seventh | 14 out |
| Saturday, July 1 |
| » Lost to Cardinals (38-27), 5-4 | Sportsman's Park III (2-3) | 23-41 | Lost 2 |
| » Starters: Mel Queen vs Howie Pollet | Seventh | 15 out |
| Sunday, July 2 |
| » Lost to Cardinals (39-27), 2-1 | Sportsman's Park III (2-4) | 23-42 | Lost 3 |
| » Starters: Bill Werle vs Red Munger | Seventh | 16 out |
| Monday, July 3 |
| » Lost to Reds (23-42), 8-5 | Crosley Field (0-4) | 23-43 | Lost 4 |
| » Starters: Bill Macdonald vs Willie Ramsdell | Seventh | 16 out |
| Tuesday, July 4 |
| » Lost to Reds (24-42), 8-4 | Crosley Field (0-5) | 23-44 | Lost 5 |
| » Starters: Cliff Chambers vs Herm Wehmeier | Eighth | 18 out |
| » Lost to Reds (25-42), 5-4 | Crosley Field (0-6) | 23-45 | Lost 6 |
| » Starters: Hank Borowy vs Howie Fox | Eighth | 18 out |
| Wednesday, July 5 |
| » Defeated Cubs (32-34), 4-1 | Wrigley Field (3-2) | 24-45 | |
| » Starters: Mel Queen vs Doyle Lade | Eighth | 18 out |
| Thursday, July 6 |
| » Lost to Cubs (33-34), 4-2 | Wrigley Field (3-3) | 24-46 | |
| » Starters: Bill Werle vs Paul Minner | Eighth | 19 out |
| Friday, July 7 |
| » Defeated Cardinals (43-28), 9-1 | Forbes Field (13-21) | 25-46 | |
| » Starters: Gerry Staley vs Vern Law | Seventh | 18 out |
| Saturday, July 8 |
| » Defeated Cardinals (43-29), 7-6 | Forbes Field (14-21) | 26-46 | Won 2 |
| » Starters: Red Munger vs Cliff Chambers | Eighth | 18 out |
| Sunday, July 9 |
| » Defeated Cardinals (43-30), 3-2 | Forbes Field (15-21) | 27-46 | Won 3 |
| » Starters: Max Lanier vs Mel Queen | Eighth | 17 out |
| Friday, July 14 |
| » Lost to Giants (35-40), 7-5 | Forbes Field (15-22) | 27-47 | |
| » Starters: Sheldon Jones vs Cliff Chambers | Eighth | 17½ out |
| » Major-league debuts: Danny O'Connell (Pirates) |
| Saturday, July 15 |
| » Defeated Giants (35-41), 2-1 | Forbes Field (16-22) | 28-47 | |
| » Starters: Larry Jansen vs Bill Werle | Seventh | 16½ out |
| Sunday, July 16 |
| » Lost to Braves (44-33), 9-5 | Forbes Field (16-23) | 28-48 | |
| » Starters: Vern Bickford vs Vern Law | Eighth | 16 out |
| » Defeated Braves (44-34), 6-5 | Forbes Field (17-23) | 29-48 | |
| » Starters: Bob Hall vs Mel Queen | Eighth | 16 out |
| Monday, July 17 |
| » Lost to Braves (45-34), 8-6 | Forbes Field (17-24) | 29-49 | |
| » Starters: Johnny Sain vs Bill Pierro | Seventh | 16 out |
| Tuesday, July 18 |
| » Lost to Braves (46-34), 11-3 | Forbes Field (17-25) | 29-50 | Lost 2 |
| » Starters: Warren Spahn vs Murry Dickson | Sixth | 16½ out |
| Wednesday, July 19 |
| » Lost to Phillies (47-34), 3-2 | Forbes Field (17-26) | 29-51 | Lost 3 |
| » Starters: Curt Simmons vs Bill Werle | Eighth | 17½ out |
| » Defeated Phillies (47-35), 4-2 | Forbes Field (18-26) | 30-51 | |
| » Starters: Russ Meyer vs Bill Macdonald | Eighth | 17½ out |
| Thursday, July 20 |
| » Defeated Phillies (47-36), 10-8 | Forbes Field (19-26) | 31-51 | Won 2 |
| » Starters: Bob Miller vs Cliff Chambers | Eighth | 16½ out |
| Friday, July 21 |
| » Lost to Phillies (48-36), 4-1 | Forbes Field (19-27) | 31-52 | |
| » Starters: Bubba Church vs Mel Queen | Seventh | 16½ out |
| Saturday, July 22 |
| » Lost to Dodgers (45-36), 12-3 | Forbes Field (19-28) | 31-53 | Lost 2 |
| » Starters: Ralph Branca vs Bill Pierro | Seventh | 17 out |
| Sunday, July 23 |
| » Lost to Dodgers (46-36), 11-6 | Forbes Field (19-29) | 31-54 | Lost 3 |
| » Starters: Erv Palica vs Bill Werle | Eighth | 18½ out |
| Monday, July 24 |
| » Defeated Phillies (51-38), 2-1 | Forbes Field (20-29) | 32-54 | |
| » Starters: Bob Miller vs Bill Macdonald | Eighth | 17½ out |
| Tuesday, July 25 |
| » Lost to Braves (48-38), 7-2 | Braves Field (2-5) | 32-55 | |
| » Starters: Bill Pierro vs Johnny Sain | Eighth | 19 out |
| Wednesday, July 26 |
| » Defeated Braves (48-39), 8-4 | Braves Field (3-5) | 33-55 | |
| » Starters: Mel Queen vs Vern Bickford | Eighth | 19 out |
| Thursday, July 27 |
| » Lost to Braves (49-39), 5-3 | Braves Field (3-6) | 33-56 | |
| » Starters: Cliff Chambers vs Warren Spahn | Eighth | 20 out |
| Friday, July 28 |
| » Lost to Phillies (56-38), 4-1 | Shibe Park (2-5) | 33-57 | Lost 2 |
| » Starters: Bill Macdonald vs Bob Miller | Eighth | 21 out |
| Saturday, July 29 |
| » Defeated Phillies (56-39), 7-4 | Shibe Park (3-5) | 34-57 | |
| » Starters: Bill Werle vs Bubba Church | Eighth | 20 out |
| Sunday, July 30 |
| » Lost to Phillies (57-39), 10-0 | Shibe Park (3-6) | 34-58 | |
| » Starters: Mel Queen vs Robin Roberts | Eighth | 22 out |
| » Lost to Phillies (58-39), 4-2 | Shibe Park (3-7) | 34-59 | Lost 2 |
| » Starters: Murry Dickson vs Ken Heintzelman | Eighth | 22 out |
| Tuesday, August 1 |
| » Lost to Dodgers (51-40), 21-12 | Ebbets Field (1-4) | 34-60 | Lost 3 |
| » Starters: Cliff Chambers vs Ralph Branca | Eighth | 23 out |
| » Lost to Dodgers (52-40), 3-1 | Ebbets Field (1-5) | 34-61 | Lost 4 |
| » Starters: Cliff Chambers vs Erv Palica | Eighth | 23 out |
| Future Pirate Milt May is born in Gary, IN. |
| Wednesday, August 2 |
| » Lost to Dodgers (53-40), 5-4 | Ebbets Field (1-6) | 34-62 | Lost 5 |
| » Starters: Bill Werle vs Ralph Branca | Eighth | 24 out |
| Friday, August 4 |
| » Lost to Giants (48-47), 3-2 | Polo Grounds V (2-2) | 34-63 | Lost 6 |
| » Starters: Vern Law vs Sheldon Jones | Eighth | 25 out |
| Saturday, August 5 |
| » Lost to Giants (49-47), 5-0 | Polo Grounds V (2-3) | 34-64 | Lost 7 |
| » Starters: Mel Queen vs Jim Hearn | Eighth | 26 out |
| Sunday, August 6 |
| » Lost to Giants (50-47), 5-0 | Polo Grounds V (2-4) | 34-65 | Lost 8 |
| » Starters: Bill Werle vs Larry Jansen | Eighth | 26 out |
| » Lost to Giants (51-47), 3-0 | Polo Grounds V (2-5) | 34-66 | Lost 9 |
| » Starters: Murry Dickson vs Sal Maglie | Eighth | 26 out |
| Tuesday, August 8 |
| » Lost to Cardinals (57-46), 6-4 | Forbes Field (20-30) | 34-67 | Lost 10 |
| » Starters: Howie Pollet vs Cliff Chambers | Eighth | 27½ out |
| Thursday, August 10 |
| » Defeated Cubs (43-58), 7-4 | Forbes Field (21-30) | 35-67 | |
| » Starters: Paul Minner vs Vern Law | Seventh | 28 out |
| Friday, August 11 |
| » Lost to Cubs (44-58), 3-1 | Forbes Field (21-31) | 35-68 | |
| » Starters: Frank Hiller vs Bill Werle | Seventh | 28 out |
| Saturday, August 12 |
| » Lost to Cubs (45-58), 7-2 | Forbes Field (21-32) | 35-69 | Lost 2 |
| » Starters: Bob Rush vs Bill Macdonald | Eighth | 29 out |
| Sunday, August 13 |
| » Defeated Cubs (45-59), 7-4 | Forbes Field (22-32) | 36-69 | |
| » Starters: Johnny Schmitz vs Cliff Chambers | Eighth | 27½ out |
| » Defeated Cubs (45-60), 2-0 | Forbes Field (23-32) | 37-69 | Won 2 |
| » Starters: Monk Dubiel vs Mel Queen | Eighth | 27½ out |
| Monday, August 14 |
| » Lost to Reds (46-59), 13-8 | Forbes Field (23-33) | 37-70 | |
| » Starters: Willie Ramsdell vs Vic Lombardi | Eighth | 28 out |
| Tuesday, August 15 |
| » Defeated Reds (46-60), 10-9 | Forbes Field (24-33) | 38-70 | |
| » Starters: Ewell Blackwell vs Bill Werle | Eighth | 28 out |
| Wednesday, August 16 |
| » Defeated Cardinals (58-51), 5-3 | Sportsman's Park III (3-4) | 39-70 | Won 2 |
| » Starters: Vern Law vs Cloyd Boyer | Eighth | 28 out |
| Thursday, August 17 |
| » Major-league debuts: George Spencer (Giants) |
| Friday, August 18 |
| » Defeated Cubs (48-62), 9-3 | Wrigley Field (4-3) | 40-70 | Won 3 |
| » Starters: Cliff Chambers vs Monk Dubiel | Eighth | 27 out |
| Saturday, August 19 |
| » Defeated Cubs (48-63), 13-8 | Wrigley Field (5-3) | 41-70 | Won 4 |
| » Starters: Mel Queen vs Doyle Lade | Eighth | 26½ out |
| Sunday, August 20 |
| » Lost to Cubs (49-63), 4-2 | Wrigley Field (5-4) | 41-71 | |
| » Starters: Vern Law vs Paul Minner | Eighth | 27½ out |
| » Lost to Cubs (50-63), 5-2 | Wrigley Field (5-5) | 41-72 | Lost 2 |
| » Starters: Bill Macdonald vs Frank Hiller | Eighth | 27½ out |
| Monday, August 21 |
| » Lost to Dodgers (61-47), 3-2 | Forbes Field (24-34) | 41-73 | Lost 3 |
| » Starters: Don Newcombe vs Bill Werle | Eighth | 28½ out |
| Tuesday, August 22 |
| » Lost to Dodgers (62-47), 10-8 | Forbes Field (24-35) | 41-74 | Lost 4 |
| » Starters: Erv Palica vs Mel Queen | Eighth | 29½ out |
| Wednesday, August 23 |
| » Lost to Dodgers (63-47), 7-5 | Forbes Field (24-36) | 41-75 | Lost 5 |
| » Starters: Carl Erskine vs Cliff Chambers | Eighth | 30½ out |
| Thursday, August 24 |
| » Lost to Phillies (73-45), 4-2 | Forbes Field (24-37) | 41-76 | Lost 6 |
| » Starters: Bubba Church vs Vern Law | Eighth | 31½ out |
| Friday, August 25 |
| » Lost to Phillies (74-45), 9-7 | Forbes Field (24-38) | 41-77 | Lost 7 |
| » Starters: Curt Simmons vs Bill Macdonald | Eighth | 32½ out |
| Saturday, August 26 |
| » Defeated Phillies (74-46), 14-4 | Forbes Field (25-38) | 42-77 | |
| » Starters: Robin Roberts vs Junior Walsh | Eighth | 31½ out |
| Sunday, August 27 |
| » Lost to Braves (65-53), 7-3 | Forbes Field (25-39) | 42-78 | |
| » Starters: Warren Spahn vs Bill Werle | Eighth | 33 out |
| » Lost to Braves (66-53), 4-1 | Forbes Field (25-40) | 42-79 | Lost 2 |
| » Starters: Normie Roy vs Mel Queen | Eighth | 33 out |
| Tuesday, August 29 |
| » Lost to Giants (63-57), 10-5 | Forbes Field (25-41) | 42-80 | Lost 3 |
| » Starters: Larry Jansen vs Vern Law | Eighth | 34 out |
| Wednesday, August 30 |
| » Lost to Giants (64-57), 4-0 | Forbes Field (25-42) | 42-81 | Lost 4 |
| » Starters: Sal Maglie vs Cliff Chambers | Eighth | 35 out |
| Thursday, August 31 |
| » Lost to Giants (65-57), 2-1 | Forbes Field (25-43) | 42-82 | Lost 5 |
| » Starters: Jim Hearn vs Bill Macdonald | Seventh | 35½ out |
| Friday, September 1 |
| » Defeated Cardinals (65-58), 10-4 | Forbes Field (26-43) | 43-82 | |
| » Starters: Cloyd Boyer vs Bill Werle | Eighth | 35½ out |
| Saturday, September 2 |
| » Defeated Cardinals (65-59), 6-0 | Forbes Field (27-43) | 44-82 | Won 2 |
| » Starters: Gerry Staley vs Vern Law | Eighth | 35½ out |
| Sunday, September 3 |
| » Defeated Cardinals (65-60), 12-11 | Forbes Field (28-43) | 45-82 | Won 3 |
| » Starters: Red Munger vs Murry Dickson | Eighth | 35 out |
| Monday, September 4 |
| » Defeated Cubs (54-73), 5-3 | Forbes Field (29-43) | 46-82 | Won 4 |
| » Starters: Monk Dubiel vs Cliff Chambers | Eighth | 33 out |
| » Defeated Cubs (54-74), 3-0 | Forbes Field (30-43) | 47-82 | Won 5 |
| » Starters: Bob Rush vs Bill Macdonald | Eighth | 33 out |
| Wednesday, September 6 |
| » Defeated Reds (53-74), 3-2 | Crosley Field (1-6) | 48-82 | Won 6 |
| » Starters: Vern Law vs Ewell Blackwell | Eighth | 31½ out |
| Thursday, September 7 |
| » Lost to Reds (54-74), 6-4 | Crosley Field (1-7) | 48-83 | |
| » Starters: Bill Werle vs Eddie Erautt | Eighth | 31½ out |
| Saturday, September 9 |
| » Defeated Cardinals (68-64), 5-4 | Sportsman's Park III (4-4) | 49-83 | |
| » Starters: Murry Dickson vs Howie Pollet | Eighth | 32 out |
| Sunday, September 10 |
| » Lost to Cardinals (69-64), 6-5 | Sportsman's Park III (4-5) | 49-84 | |
| » Starters: Cliff Chambers vs Red Munger | Eighth | 31½ out |
| » Defeated Cardinals (69-65), 6-2 | Sportsman's Park III (5-5) | 50-84 | |
| » Starters: Bill Macdonald vs Erv Dusak | Eighth | 31½ out |
| Tuesday, September 12 |
| » Lost to Giants (73-60), 3-0 | Polo Grounds V (2-6) | 50-85 | |
| » Starters: Bill Werle vs Sheldon Jones | Eighth | 32½ out |
| Wednesday, September 13 |
| » Lost to Giants (74-60), 3-1 | Polo Grounds V (2-7) | 50-86 | Lost 2 |
| » Starters: Vern Law vs Sal Maglie | Eighth | 33 out |
| Thursday, September 14 |
| » Defeated Giants (74-61), 7-1 | Polo Grounds V (3-7) | 51-86 | |
| » Starters: Murry Dickson vs Larry Jansen | Eighth | 33½ out |
| » Lost to Giants (75-61), 6-1 | Polo Grounds V (3-8) | 51-87 | |
| » Starters: Bill Macdonald vs Jim Hearn | Eighth | 33½ out |
| Friday, September 15 |
| » Lost to Braves (76-59), 7-4 | Braves Field (3-7) | 51-88 | Lost 2 |
| » Starters: Mel Queen vs Max Surkont | Eighth | 35 out |
| Saturday, September 16 |
| » Defeated Braves (76-60), 4-0 | Braves Field (4-7) | 52-88 | |
| » Starters: Cliff Chambers vs Vern Bickford | Eighth | 34 out |
| Sunday, September 17 |
| » Lost to Phillies (87-54), 5-3 | Shibe Park (3-8) | 52-89 | |
| » Starters: Bill Werle vs Russ Meyer | Eighth | 35 out |
| Tuesday, September 19 |
| » Lost to Dodgers (77-61), 14-3 | Ebbets Field (1-7) | 52-90 | Lost 2 |
| » Starters: Vern Law vs Don Newcombe | Eighth | 35½ out |
| » Lost to Dodgers (78-61), 3-2 | Ebbets Field (1-8) | 52-91 | Lost 3 |
| » Starters: Murry Dickson vs Erv Palica | Eighth | 35½ out |
| Wednesday, September 20 |
| » Lost to Dodgers (79-61), 7-2 | Ebbets Field (1-9) | 52-92 | Lost 4 |
| » Starters: Bill Macdonald vs Carl Erskine | Seventh | 36½ out |
| Thursday, September 21 |
| » Lost to Dodgers (80-61), 10-8 | Ebbets Field (1-10) | 52-93 | Lost 5 |
| » Starters: Bill Werle vs Jim Romano | Seventh | 37 out |
| Friday, September 22 |
| » Defeated Reds (62-82), 8-7 | Forbes Field (31-43) | 53-93 | |
| » Starters: Willie Ramsdell vs Cliff Chambers | Seventh | 36½ out |
| Saturday, September 23 |
| » Defeated Reds (62-83), 8-7 | Forbes Field (32-43) | 54-93 | Won 2 |
| » Starters: Herm Wehmeier vs Vern Law | Eighth | 35½ out |
| Sunday, September 24 |
| » Lost to Reds (63-83), 7-1 | Forbes Field (32-44) | 54-94 | |
| » Starters: Ewell Blackwell vs Bill Macdonald | Eighth | 35 out |
| » Defeated Reds (63-84), 3-2 | Forbes Field (33-44) | 55-94 | |
| » Starters: Ken Raffensberger vs Murry Dickson | Eighth | 35 out |
| Wednesday, September 27 |
| » Defeated Cubs (63-86), 7-4 | Wrigley Field (6-5) | 56-94 | Won 2 |
| » Starters: Bob Chesnes vs Johnny Klippstein | Eighth | 34 out |
| » Major-league debuts: Harry Chiti (Cubs) |
| Thursday, September 28 |
| » Major-league debuts: Don Bollweg (Cardinals) |
| Friday, September 29 |
| Future Pirate Ken Macha is born in Monroeville, PA. |
| Saturday, September 30 |
| » Lost to Reds (65-86), 5-2 | Crosley Field (1-8) | 56-95 | |
| » Starters: Bill Werle vs Howie Fox | Eighth | 33 out |
| Sunday, October 1 |
| » Lost to Reds (66-86), 3-2 | Crosley Field (1-9) | 56-96 | Lost 2 |
| » Starters: Murry Dickson vs Willie Ramsdell | Eighth | 33½ out |
| » Defeated Reds (66-87), 3-1 | Crosley Field (2-9) | 57-96 | |
| » Starters: Cliff Chambers vs Bud Byerly | Eighth | 33½ out |
| Wednesday, November 29 |
| Future Pirate Mike Easler is born in Cleveland, OH. |
| Friday, December 8 |
| Future Pirate Tim Foli is born in Culver City, CA. |
| Tuesday, December 26 |
| Future Pirate Mario Mendoza is born in Chihuahua, Mexico. |
Game information provided by Retrosheet (www.retrosheet.org) |
