| Saturday, February 11 |
| Former Brown Paul Meloan dies in Taft, CA at the age of 62. |
| Tuesday, April 18 |
| » Defeated White Sox (0-1), 5-3 | Comiskey Park I (1-0) | 1-0 | |
| » Starters: Ned Garver vs Bill Wight | First | -- |
| » Major-league debuts: Chico Carrasquel (White Sox) Don Lenhardt (Browns) |
| Wednesday, April 19 |
| » Defeated White Sox (0-2), 6-1 | Comiskey Park I (2-0) | 2-0 | Won 2 |
| » Starters: Dick Starr vs Bob Kuzava | First | -- |
| » Major-league debuts: Luis Aloma (White Sox) |
| Saturday, April 22 |
| » Lost to Indians (1-2), 6-2 | Sportsman's Park III (0-1) | 2-1 | |
| » Starters: Bob Feller vs Stubby Overmire | Second | 1½ out |
| Sunday, April 23 |
| » Lost to Indians (2-2), 9-6 | Sportsman's Park III (0-2) | 2-2 | Lost 2 |
| » Starters: Bob Lemon vs Ed Albrecht | Sixth | 2 out |
| » Lost to Indians (3-2), 7-5 | Sportsman's Park III (0-3) | 2-3 | Lost 3 |
| » Starters: Sam Zoldak vs Ned Garver | Sixth | 2 out |
| » Major-league debuts: Sid Schacht (Browns) |
| Tuesday, April 25 |
| » Lost to Tigers (5-1), 5-2 | Sportsman's Park III (0-4) | 2-4 | Lost 4 |
| » Starters: Virgil Trucks vs Dick Starr | Sixth | 3 out |
| » Major-league debuts: Lou Sleater (Browns) |
| Wednesday, April 26 |
| » Lost to Tigers (6-1), 8-6 | Sportsman's Park III (0-5) | 2-5 | Lost 5 |
| » Starters: Saul Rogovin vs Cliff Fannin | Seventh | 4 out |
| Saturday, April 29 |
| » Defeated Indians (4-3), 5-1 | Cleveland Stadium (1-0) | 3-5 | |
| » Starters: Joe Ostrowski vs Bob Lemon | Seventh | 3 out |
| » Major-league debuts: Dick Rozek (Indians) |
| Wednesday, May 3 |
| » Lost to Senators (6-4), 4-3 | Griffith Stadium (0-1) | 3-6 | |
| » Starters: Ned Garver vs Sid Hudson | Sixth | 3 out |
| Thursday, May 4 |
| » Defeated Senators (6-5), 5-1 | Griffith Stadium (1-1) | 4-6 | |
| » Starters: Joe Ostrowski vs Dick Weik | Sixth | 3 out |
| Saturday, May 6 |
| » Lost to Athletics (5-9), 12-4 | Shibe Park (0-1) | 4-7 | |
| » Starters: Dick Starr vs Alex Kellner | Sixth | 4½ out |
| Sunday, May 7 |
| » Lost to Red Sox (12-7), 8-6 | Fenway Park (0-1) | 4-8 | Lost 2 |
| » Starters: Ned Garver vs Mickey McDermott | Eighth | 5 out |
| » Lost to Red Sox (13-7), 6-2 | Fenway Park (0-2) | 4-9 | Lost 3 |
| » Starters: Cliff Fannin vs Al Papai | Eighth | 5 out |
| Tuesday, May 9 |
| » Lost to Yankees (10-7), 4-2 | Yankee Stadium (0-1) | 4-10 | Lost 4 |
| » Starters: Joe Ostrowski vs Eddie Lopat | Eighth | 6½ out |
| Thursday, May 11 |
| » Lost to Yankees (11-7), 5-1 | Yankee Stadium (0-2) | 4-11 | Lost 5 |
| » Starters: Al Widmar vs Allie Reynolds | Eighth | 7½ out |
| » Lost to Yankees (12-7), 6-5 | Yankee Stadium (0-3) | 4-12 | Lost 6 |
| » Starters: Dick Starr vs Fred Sanford | Eighth | 7½ out |
| Saturday, May 13 |
| » Lost to Tigers (13-5), 1-0 | Tiger Stadium (0-1) | 4-13 | Lost 7 |
| » Starters: Ned Garver vs Virgil Trucks | Seventh | 8½ out |
| Sunday, May 14 |
| » Defeated Tigers (13-6), 7-3 | Tiger Stadium (1-1) | 5-13 | |
| » Starters: Cliff Fannin vs Hal Newhouser | Seventh | 7½ out |
| Tuesday, May 16 |
| » Lost to Yankees (15-8), 11-0 | Sportsman's Park III (0-6) | 5-14 | |
| » Starters: Allie Reynolds vs Joe Ostrowski | Seventh | 8 out |
| Wednesday, May 17 |
| » Lost to Yankees (16-8), 11-9 | Sportsman's Park III (0-7) | 5-15 | Lost 2 |
| » Starters: Fred Sanford vs Al Widmar | Seventh | 9 out |
| Saturday, May 20 |
| » Defeated Senators (15-11), 3-0 | Sportsman's Park III (1-7) | 6-15 | |
| » Starters: Dick Weik vs Ned Garver | Sixth | 9½ out |
| Sunday, May 21 |
| » Defeated Athletics (9-19), 11-6 | Sportsman's Park III (2-7) | 7-15 | Won 2 |
| » Starters: Alex Kellner vs Cliff Fannin | Seventh | 10½ out |
| » Lost to Athletics (10-19), 8-3 | Sportsman's Park III (2-8) | 7-16 | |
| » Starters: Bob Hooper vs Joe Ostrowski | Seventh | 10½ out |
| Tuesday, May 23 |
| » Defeated Athletics (10-20), 7-1 | Sportsman's Park III (3-8) | 8-16 | |
| » Starters: Carl Scheib vs Al Widmar | Sixth | 10½ out |
| Wednesday, May 24 |
| » Lost to Red Sox (21-15), 7-5 | Sportsman's Park III (3-9) | 8-17 | |
| » Starters: Mel Parnell vs Lou Kretlow | Seventh | 11 out |
| Thursday, May 25 |
| » Lost to Red Sox (22-15), 15-12 | Sportsman's Park III (3-10) | 8-18 | Lost 2 |
| » Starters: Ellis Kinder vs Ned Garver | Sixth | 12 out |
| Friday, May 26 |
| » Lost to Tigers (18-11), 11-2 | Sportsman's Park III (3-11) | 8-19 | Lost 3 |
| » Starters: Hal Newhouser vs Cliff Fannin | Seventh | 13 out |
| Saturday, May 27 |
| » Lost to Tigers (19-11), 8-6 | Sportsman's Park III (3-12) | 8-20 | Lost 4 |
| » Starters: Ted Gray vs Joe Ostrowski | Eighth | 13 out |
| Sunday, May 28 |
| » Lost to Tigers (20-11), 6-2 | Sportsman's Park III (3-13) | 8-21 | Lost 5 |
| » Starters: Fred Hutchinson vs Al Widmar | Eighth | 14 out |
| » Lost to Tigers (21-11), 2-1 | Sportsman's Park III (3-14) | 8-22 | Lost 6 |
| » Starters: Dizzy Trout vs Fritz Dorish | Eighth | 14 out |
| Monday, May 29 |
| » Lost to White Sox (11-23), 12-8 | Sportsman's Park III (3-15) | 8-23 | Lost 7 |
| » Starters: Randy Gumpert vs Sid Schacht | Eighth | 14½ out |
| Tuesday, May 30 |
| » Lost to White Sox (12-23), 14-2 | Sportsman's Park III (3-16) | 8-24 | Lost 8 |
| » Starters: Bob Kuzava vs Ned Garver | Eighth | 16½ out |
| » Lost to White Sox (13-23), 12-9 | Sportsman's Park III (3-17) | 8-25 | Lost 9 |
| » Starters: Ken Holcombe vs Cliff Fannin | Eighth | 16½ out |
| Thursday, June 1 |
| » Defeated Senators (19-18), 5-4 | Griffith Stadium (2-1) | 9-25 | |
| » Starters: Joe Ostrowski vs Connie Marrero | Eighth | 16½ out |
| Friday, June 2 |
| » Defeated Senators (19-19), 10-5 | Griffith Stadium (3-1) | 10-25 | Won 2 |
| » Starters: Al Widmar vs Sid Hudson | Eighth | 15 out |
| » Defeated Senators (19-20), 9-3 | Griffith Stadium (4-1) | 11-25 | Won 3 |
| » Starters: Fritz Dorish vs Lloyd Hittle | Eighth | 15 out |
| Sunday, June 4 |
| » Defeated Athletics (14-28), 12-5 | Shibe Park (1-1) | 12-25 | Won 4 |
| » Starters: Ned Garver vs Carl Scheib | Eighth | 16½ out |
| » Lost to Athletics (15-28), 13-6 | Shibe Park (1-2) | 12-26 | |
| » Starters: Lou Kretlow vs Bob Hooper | Eighth | 16½ out |
| Tuesday, June 6 |
| » Defeated Athletics (15-29), 6-5 | Shibe Park (2-2) | 13-26 | |
| » Starters: Cliff Fannin vs Lou Brissie | Eighth | 14½ out |
| Wednesday, June 7 |
| » Lost to Red Sox (29-19), 20-4 | Fenway Park (0-3) | 13-27 | |
| » Starters: Fritz Dorish vs Joe Dobson | Eighth | 16 out |
| Thursday, June 8 |
| » Lost to Red Sox (30-19), 29-4 | Fenway Park (0-4) | 13-28 | Lost 2 |
| » Starters: Cliff Fannin vs Chuck Stobbs | Eighth | 17 out |
| Friday, June 9 |
| » Defeated Red Sox (30-20), 12-7 | Fenway Park (1-4) | 14-28 | |
| » Starters: Ned Garver vs Mickey McDermott | Eighth | 16 out |
| Saturday, June 10 |
| » Defeated Yankees (32-15), 7-2 | Yankee Stadium (1-3) | 15-28 | Won 2 |
| » Starters: Dick Starr vs Allie Reynolds | Seventh | 14½ out |
| Sunday, June 11 |
| » Lost to Yankees (33-15), 1-0 | Yankee Stadium (1-4) | 15-29 | |
| » Starters: Stubby Overmire vs Vic Raschi | Eighth | 16½ out |
| » Lost to Yankees (34-15), 4-2 | Yankee Stadium (1-5) | 15-30 | Lost 2 |
| » Starters: Al Widmar vs Fred Sanford | Eighth | 16½ out |
| Tuesday, June 13 |
| » Defeated Senators (22-27), 8-3 | Sportsman's Park III (4-17) | 16-30 | |
| » Starters: Sid Hudson vs Fritz Dorish | Seventh | 16 out |
| » Defeated Senators (22-28), 6-1 | Sportsman's Park III (5-17) | 17-30 | Won 2 |
| » Starters: Bob Kuzava vs Cliff Fannin | Seventh | 16 out |
| Wednesday, June 14 |
| » Lost to Senators (23-28), 4-1 | Sportsman's Park III (5-18) | 17-31 | |
| » Starters: Connie Marrero vs Ned Garver | Eighth | 16 out |
| Thursday, June 15 |
| » Defeated Senators (23-29), 16-9 | Sportsman's Park III (6-18) | 18-31 | |
| » Starters: Sandy Consuegra vs Dick Starr | Seventh | 16 out |
| Friday, June 16 |
| » Lost to Yankees (35-18), 7-5 | Sportsman's Park III (6-19) | 18-32 | |
| » Starters: Vic Raschi vs Al Widmar | Seventh | 17 out |
| Saturday, June 17 |
| » Defeated Yankees (35-19), 7-3 | Sportsman's Park III (7-19) | 19-32 | |
| » Starters: Fred Sanford vs Stubby Overmire | Seventh | 17 out |
| Sunday, June 18 |
| » Lost to Yankees (36-19), 15-5 | Sportsman's Park III (7-20) | 19-33 | |
| » Starters: Tommy Byrne vs Cliff Fannin | Seventh | 18½ out |
| » Lost to Yankees (37-19), 9-0 | Sportsman's Park III (7-21) | 19-34 | Lost 2 |
| » Starters: Allie Reynolds vs Fritz Dorish | Seventh | 18½ out |
| Tuesday, June 20 |
| » Defeated Athletics (19-39), 1-0 | Sportsman's Park III (8-21) | 20-34 | |
| » Starters: Lou Brissie vs Ned Garver | Seventh | 17½ out |
| Wednesday, June 21 |
| » Lost to Athletics (20-39), 4-2 | Sportsman's Park III (8-22) | 20-35 | |
| » Starters: Bob Hooper vs Al Widmar | Seventh | 17½ out |
| Thursday, June 22 |
| » Lost to Athletics (21-39), 8-4 | Sportsman's Park III (8-23) | 20-36 | Lost 2 |
| » Starters: Bobby Shantz vs Stubby Overmire | Seventh | 17½ out |
| Friday, June 23 |
| » Lost to Red Sox (33-30), 12-9 | Sportsman's Park III (8-24) | 20-37 | Lost 3 |
| » Starters: Chuck Stobbs vs Fritz Dorish | Seventh | 18½ out |
| Saturday, June 24 |
| » Lost to Red Sox (34-30), 12-3 | Sportsman's Park III (8-25) | 20-38 | Lost 4 |
| » Starters: Ellis Kinder vs Cliff Fannin | Seventh | 19½ out |
| Sunday, June 25 |
| » Lost to Red Sox (35-30), 11-5 | Sportsman's Park III (8-26) | 20-39 | Lost 5 |
| » Starters: Joe Dobson vs Ned Garver | Eighth | 20½ out |
| » Lost to Red Sox (36-30), 8-2 | Sportsman's Park III (8-27) | 20-40 | Lost 6 |
| » Starters: Walt Masterson vs Stubby Overmire | Eighth | 20½ out |
| Tuesday, June 27 |
| » Defeated Indians (36-27), 4-3 | Sportsman's Park III (9-27) | 21-40 | |
| » Starters: Bob Feller vs Al Widmar | Seventh | 21 out |
| Wednesday, June 28 |
| » Lost to Indians (37-27), 18-2 | Sportsman's Park III (9-28) | 21-41 | |
| » Starters: Bob Lemon vs Fritz Dorish | Seventh | 22 out |
| Thursday, June 29 |
| » Lost to Indians (38-27), 4-1 | Sportsman's Park III (9-29) | 21-42 | Lost 2 |
| » Starters: Steve Gromek vs Duane Pillette | Seventh | 22 out |
| Friday, June 30 |
| » Lost to White Sox (29-37), 3-2 | Comiskey Park I (2-1) | 21-43 | Lost 3 |
| » Starters: Ned Garver vs Bill Wight | Eighth | 22 out |
| Former Brown Joe Lake dies in Brooklyn, NY at the age of 70. |
| Saturday, July 1 |
| » Lost to White Sox (30-37), 4-1 | Comiskey Park I (2-2) | 21-44 | Lost 4 |
| » Starters: Stubby Overmire vs Billy Pierce | Eighth | 22 out |
| Sunday, July 2 |
| » Lost to White Sox (31-37), 5-2 | Comiskey Park I (2-3) | 21-45 | Lost 5 |
| » Starters: Fritz Dorish vs Rae Scarborough | Seventh | 22 out |
| » Defeated White Sox (31-38), 4-3 | Comiskey Park I (3-3) | 22-45 | |
| » Starters: Al Widmar vs Randy Gumpert | Seventh | 22 out |
| Monday, July 3 |
| » Defeated Indians (41-29), 4-2 | Cleveland Stadium (2-0) | 23-45 | Won 2 |
| » Starters: Dick Starr vs Steve Gromek | Eighth | 22 out |
| Tuesday, July 4 |
| » Lost to Indians (42-29), 8-7 | Cleveland Stadium (2-1) | 23-46 | |
| » Starters: Duane Pillette vs Dick Rozek | Eighth | 22 out |
| » Defeated Indians (42-30), 8-3 | Cleveland Stadium (3-1) | 24-46 | |
| » Starters: Don Johnson vs Mike Garcia | Eighth | 22 out |
| Wednesday, July 5 |
| » Lost to Tigers (47-24), 6-1 | Tiger Stadium (1-2) | 24-47 | |
| » Starters: Ned Garver vs Art Houtteman | Eighth | 23 out |
| Friday, July 7 |
| » Lost to White Sox (33-42), 5-2 | Sportsman's Park III (9-30) | 24-48 | Lost 2 |
| » Starters: Bob Cain vs Fritz Dorish | Seventh | 23½ out |
| » Defeated White Sox (33-43), 4-3 | Sportsman's Park III (10-30) | 25-48 | |
| » Starters: Randy Gumpert vs Al Widmar | Seventh | 23½ out |
| Saturday, July 8 |
| » Lost to White Sox (34-43), 7-5 | Sportsman's Park III (10-31) | 25-49 | |
| » Starters: Ken Holcombe vs Stubby Overmire | Eighth | 24 out |
| » Defeated White Sox (34-44), 11-5 | Sportsman's Park III (11-31) | 26-49 | |
| » Starters: Mickey Haefner vs Duane Pillette | Eighth | 24 out |
| Sunday, July 9 |
| » Defeated White Sox (34-45), 4-2 | Sportsman's Park III (12-31) | 27-49 | Won 2 |
| » Starters: Billy Pierce vs Ned Garver | Seventh | 22½ out |
| Friday, July 14 |
| » Lost to Athletics (28-49), 3-2 | Shibe Park (2-3) | 27-50 | |
| » Starters: Don Johnson vs Lou Brissie | Seventh | 23½ out |
| » Defeated Athletics (28-50), 5-2 | Shibe Park (3-3) | 28-50 | |
| » Starters: Al Widmar vs Bobby Shantz | Seventh | 23½ out |
| Saturday, July 15 |
| » Defeated Athletics (28-51), 3-2 | Shibe Park (4-3) | 29-50 | Won 2 |
| » Starters: Ned Garver vs Dick Fowler | Seventh | 23 out |
| Sunday, July 16 |
| » Lost to Senators (36-43), 5-1 | Griffith Stadium (4-2) | 29-51 | |
| » Starters: Stubby Overmire vs Sid Hudson | Seventh | 23 out |
| » Defeated Senators (36-44), 10-8 | Griffith Stadium (5-2) | 30-51 | |
| » Starters: Fritz Dorish vs Rogelio Martinez | Seventh | 23 out |
| Monday, July 17 |
| » Lost to Senators (37-44), 3-1 | Griffith Stadium (5-3) | 30-52 | |
| » Starters: Duane Pillette vs Bob Kuzava | Seventh | 24½ out |
| Tuesday, July 18 |
| » Lost to Yankees (51-32), 12-1 | Yankee Stadium (1-6) | 30-53 | Lost 2 |
| » Starters: Don Johnson vs Tommy Byrne | Seventh | 24½ out |
| Wednesday, July 19 |
| » Lost to Yankees (52-32), 16-1 | Yankee Stadium (1-7) | 30-54 | Lost 3 |
| » Starters: Al Widmar vs Eddie Lopat | Seventh | 26 out |
| » Lost to Yankees (53-32), 4-3 | Yankee Stadium (1-8) | 30-55 | Lost 4 |
| » Starters: Ned Garver vs Fred Sanford | Seventh | 26 out |
| Friday, July 21 |
| » Lost to Red Sox (49-39), 7-4 | Fenway Park (1-5) | 30-56 | Lost 5 |
| » Starters: Fritz Dorish vs Joe Dobson | Seventh | 25½ out |
| Saturday, July 22 |
| » Lost to Red Sox (50-39), 11-2 | Fenway Park (1-6) | 30-57 | Lost 6 |
| » Starters: Dick Starr vs Mickey McDermott | Seventh | 25½ out |
| Sunday, July 23 |
| » Lost to Red Sox (51-39), 6-2 | Fenway Park (1-7) | 30-58 | Lost 7 |
| » Starters: Don Johnson vs Ellis Kinder | Eighth | 26½ out |
| Tuesday, July 25 |
| » Defeated Yankees (55-34), 4-3 | Sportsman's Park III (13-31) | 31-58 | |
| » Starters: Vic Raschi vs Stubby Overmire | Eighth | 25½ out |
| Wednesday, July 26 |
| » Lost to Yankees (56-34), 6-3 | Sportsman's Park III (13-32) | 31-59 | |
| » Starters: Whitey Ford vs Ned Garver | Eighth | 25½ out |
| Thursday, July 27 |
| » Defeated Yankees (56-35), 3-2 | Sportsman's Park III (14-32) | 32-59 | |
| » Starters: Tommy Byrne vs Al Widmar | Eighth | 25½ out |
| Friday, July 28 |
| » Defeated Senators (42-48), 5-4 | Sportsman's Park III (15-32) | 33-59 | Won 2 |
| » Starters: Bob Kuzava vs Fritz Dorish | Eighth | 24½ out |
| Saturday, July 29 |
| » Defeated Senators (42-49), 10-9 | Sportsman's Park III (16-32) | 34-59 | Won 3 |
| » Starters: Sandy Consuegra vs Cuddles Marshall | Seventh | 24½ out |
| Sunday, July 30 |
| » Lost to Senators (43-49), 9-5 | Sportsman's Park III (16-33) | 34-60 | |
| » Starters: Joe Haynes vs Stubby Overmire | Seventh | 26 out |
| » Lost to Senators (44-49), 13-8 | Sportsman's Park III (16-34) | 34-61 | Lost 2 |
| » Starters: Elmer Singleton vs Ned Garver | Seventh | 26 out |
| Tuesday, August 1 |
| » Lost to Red Sox (55-43), 7-3 | Sportsman's Park III (16-35) | 34-62 | Lost 3 |
| » Starters: Mel Parnell vs Cuddles Marshall | Seventh | 27 out |
| Wednesday, August 2 |
| » Lost to Red Sox (56-43), 9-8 | Sportsman's Park III (16-36) | 34-63 | Lost 4 |
| » Starters: Mickey McDermott vs Al Widmar | Eighth | 28 out |
| Friday, August 4 |
| » Lost to Athletics (36-64), 12-9 | Sportsman's Park III (16-37) | 34-64 | Lost 5 |
| » Starters: Lou Brissie vs Fritz Dorish | Eighth | 28½ out |
| Saturday, August 5 |
| » Defeated Athletics (36-65), 4-0 | Sportsman's Park III (17-37) | 35-64 | |
| » Starters: Alex Kellner vs Stubby Overmire | Eighth | 28½ out |
| Sunday, August 6 |
| » Defeated Athletics (36-66), 10-3 | Sportsman's Park III (18-37) | 36-64 | Won 2 |
| » Starters: Carl Scheib vs Ned Garver | Seventh | 28½ out |
| Wednesday, August 9 |
| » Lost to Indians (63-40), 4-3 | Sportsman's Park III (18-38) | 36-65 | |
| » Starters: Bob Feller vs Al Widmar | Eighth | 28½ out |
| » Defeated Indians (63-41), 10-8 | Sportsman's Park III (19-38) | 37-65 | |
| » Starters: Early Wynn vs Dick Starr | Eighth | 28½ out |
| Thursday, August 10 |
| » Lost to Indians (64-41), 5-4 | Sportsman's Park III (19-39) | 37-66 | |
| » Starters: Bob Lemon vs Stubby Overmire | Eighth | 29½ out |
| Friday, August 11 |
| » Lost to Tigers (67-36), 4-3 | Sportsman's Park III (19-40) | 37-67 | Lost 2 |
| » Starters: Dizzy Trout vs Ned Garver | Eighth | 29½ out |
| » Defeated Tigers (67-37), 2-1 | Sportsman's Park III (20-40) | 38-67 | |
| » Starters: Hank Borowy vs Don Johnson | Eighth | 29½ out |
| Wednesday, August 16 |
| » Lost to Indians (68-44), 2-0 | Cleveland Stadium (3-2) | 38-68 | |
| » Starters: Al Widmar vs Jesse Flores | Eighth | 31 out |
| » Lost to Indians (69-44), 2-1 | Cleveland Stadium (3-3) | 38-69 | Lost 2 |
| » Starters: Don Johnson vs Mike Garcia | Eighth | 31 out |
| Thursday, August 17 |
| » Lost to Indians (70-44), 5-4 | Cleveland Stadium (3-4) | 38-70 | Lost 3 |
| » Starters: Dick Starr vs Bob Feller | Eighth | 32 out |
| Saturday, August 19 |
| » Lost to Tigers (71-38), 6-0 | Tiger Stadium (1-3) | 38-71 | Lost 4 |
| » Starters: Ned Garver vs Art Houtteman | Seventh | 33 out |
| Sunday, August 20 |
| » Lost to Tigers (72-38), 5-4 | Tiger Stadium (1-4) | 38-72 | Lost 5 |
| » Starters: Duane Pillette vs Fred Hutchinson | Seventh | 33 out |
| » Defeated Tigers (72-39), 6-2 | Tiger Stadium (2-4) | 39-72 | |
| » Starters: Stubby Overmire vs Hal Newhouser | Seventh | 33 out |
| Monday, August 21 |
| » Lost to Tigers (73-39), 7-1 | Tiger Stadium (2-5) | 39-73 | |
| » Starters: Al Widmar vs Dizzy Trout | Seventh | 34 out |
| Tuesday, August 22 |
| » Lost to Red Sox (70-48), 9-5 | Fenway Park (1-8) | 39-74 | Lost 2 |
| » Starters: Don Johnson vs Willard Nixon | Seventh | 34 out |
| Wednesday, August 23 |
| » Lost to Red Sox (71-48), 9-5 | Fenway Park (1-9) | 39-75 | Lost 3 |
| » Starters: Dick Starr vs Chuck Stobbs | Eighth | 34 out |
| Thursday, August 24 |
| » Lost to Red Sox (72-48), 6-2 | Fenway Park (1-10) | 39-76 | Lost 4 |
| » Starters: Ned Garver vs Walt Masterson | Eighth | 35 out |
| Friday, August 25 |
| » Lost to Yankees (74-45), 10-0 | Yankee Stadium (1-9) | 39-77 | Lost 5 |
| » Starters: Cliff Fannin vs Whitey Ford | Eighth | 35 out |
| Saturday, August 26 |
| » Lost to Yankees (75-45), 3-2 | Yankee Stadium (1-10) | 39-78 | Lost 6 |
| » Starters: Stubby Overmire vs Eddie Lopat | Eighth | 36 out |
| Sunday, August 27 |
| » Lost to Senators (52-66), 8-0 | Griffith Stadium (5-4) | 39-79 | Lost 7 |
| » Starters: Al Widmar vs Joe Haynes | Eighth | 36 out |
| » Defeated Senators (52-67), 11-10 | Griffith Stadium (6-4) | 40-79 | |
| » Starters: Don Johnson vs Bob Kuzava | Eighth | 36 out |
| Monday, August 28 |
| » Lost to Senators (53-67), 9-3 | Griffith Stadium (6-5) | 40-80 | |
| » Starters: Jack Bruner vs Jim Pearce | Eighth | 36 out |
| Wednesday, August 30 |
| » Defeated Athletics (43-82), 2-1 | Shibe Park (5-3) | 41-80 | |
| » Starters: Ned Garver vs Alex Kellner | Seventh | 35½ out |
| » Defeated Athletics (43-83), 7-6 | Shibe Park (6-3) | 42-80 | Won 2 |
| » Starters: Al Widmar vs Hank Wyse | Seventh | 35½ out |
| Thursday, August 31 |
| » Defeated Athletics (43-84), 4-3 | Shibe Park (7-3) | 43-80 | Won 3 |
| » Starters: Dick Starr vs Lou Brissie | Seventh | 36 out |
| » Lost to Athletics (44-84), 3-2 | Shibe Park (7-4) | 43-81 | |
| » Starters: Cliff Fannin vs Bob Hooper | Seventh | 36 out |
| Saturday, September 2 |
| » Lost to Indians (77-52), 4-2 | Sportsman's Park III (20-41) | 43-82 | Lost 2 |
| » Starters: Early Wynn vs Stubby Overmire | Eighth | 37½ out |
| Sunday, September 3 |
| » Lost to Indians (78-52), 8-1 | Sportsman's Park III (20-42) | 43-83 | Lost 3 |
| » Starters: Bob Feller vs Don Johnson | Eighth | 38 out |
| Monday, September 4 |
| » Lost to Tigers (80-47), 4-2 | Tiger Stadium (2-6) | 43-84 | Lost 4 |
| » Starters: Ned Garver vs Art Houtteman | Eighth | 38 out |
| » Defeated Tigers (80-48), 5-4 | Tiger Stadium (3-6) | 44-84 | |
| » Starters: Al Widmar vs Dizzy Trout | Eighth | 38 out |
| Tuesday, September 5 |
| » Lost to Tigers (81-48), 7-4 | Tiger Stadium (3-7) | 44-85 | |
| » Starters: Duane Pillette vs Ray Herbert | Eighth | 38½ out |
| Wednesday, September 6 |
| » Lost to White Sox (52-81), 6-5 | Comiskey Park I (3-4) | 44-86 | Lost 2 |
| » Starters: Cliff Fannin vs Rae Scarborough | Eighth | 38½ out |
| Thursday, September 7 |
| » Defeated White Sox (52-82), 6-0 | Comiskey Park I (4-4) | 45-86 | |
| » Starters: Dick Starr vs Howie Judson | Eighth | 37½ out |
| Friday, September 8 |
| » Defeated Indians (80-55), 5-4 | Cleveland Stadium (4-4) | 46-86 | Won 2 |
| » Starters: Al Widmar vs Mike Garcia | Seventh | 37 out |
| » Defeated Indians (80-56), 6-0 | Cleveland Stadium (5-4) | 47-86 | Won 3 |
| » Starters: Don Johnson vs Bob Lemon | Seventh | 37 out |
| Saturday, September 9 |
| » Defeated Indians (80-57), 2-1 | Cleveland Stadium (6-4) | 48-86 | Won 4 |
| » Starters: Ned Garver vs Steve Gromek | Seventh | 37 out |
| Sunday, September 10 |
| » Defeated Indians (80-58), 2-1 | Cleveland Stadium (7-4) | 49-86 | Won 5 |
| » Starters: Stubby Overmire vs Bob Feller | Seventh | 36½ out |
| Tuesday, September 12 |
| » Defeated Athletics (47-92), 6-0 | Sportsman's Park III (21-42) | 50-86 | Won 6 |
| » Starters: Bob Hooper vs Al Widmar | Seventh | 36½ out |
| Wednesday, September 13 |
| » Defeated Athletics (47-93), 4-3 | Sportsman's Park III (22-42) | 51-86 | Won 7 |
| » Starters: Lou Brissie vs Ned Garver | Seventh | 36½ out |
| Thursday, September 14 |
| » Defeated Red Sox (86-52), 6-3 | Sportsman's Park III (23-42) | 52-86 | Won 8 |
| » Starters: Willard Nixon vs Dick Starr | Seventh | 36 out |
| Friday, September 15 |
| » Lost to Red Sox (87-52), 12-9 | Sportsman's Park III (23-43) | 52-87 | |
| » Starters: Joe Dobson vs Don Johnson | Seventh | 36½ out |
| Saturday, September 16 |
| » Defeated Red Sox (87-53), 5-2 | Sportsman's Park III (24-43) | 53-87 | |
| » Starters: Walt Masterson vs Cliff Fannin | Seventh | 36 out |
| Sunday, September 17 |
| » Defeated Yankees (89-52), 6-5 | Sportsman's Park III (25-43) | 54-87 | Won 2 |
| » Starters: Eddie Lopat vs Stubby Overmire | Seventh | 36 out |
| » Lost to Yankees (90-52), 6-1 | Sportsman's Park III (25-44) | 54-88 | |
| » Starters: Allie Reynolds vs Al Widmar | Seventh | 36 out |
| Tuesday, September 19 |
| » Lost to Senators (62-80), 5-3 | Sportsman's Park III (25-45) | 54-89 | Lost 2 |
| » Starters: Joe Haynes vs Ned Garver | Sixth | 36 out |
| Wednesday, September 20 |
| » Lost to Senators (63-80), 12-7 | Sportsman's Park III (25-46) | 54-90 | Lost 3 |
| » Starters: Sid Hudson vs Dick Starr | Seventh | 37 out |
| Saturday, September 23 |
| » Lost to White Sox (58-89), 12-5 | Sportsman's Park III (25-47) | 54-91 | Lost 4 |
| » Starters: Billy Pierce vs Al Widmar | Seventh | 38 out |
| Sunday, September 24 |
| » Defeated White Sox (58-90), 5-0 | Sportsman's Park III (26-47) | 55-91 | |
| » Starters: Randy Gumpert vs Stubby Overmire | Seventh | 37½ out |
| » Defeated White Sox (58-91), 6-1 | Sportsman's Park III (27-47) | 56-91 | Won 2 |
| » Starters: Bill Wight vs Ned Garver | Seventh | 37½ out |
| » Major-league debuts: Bill Wilson (White Sox) |
| Tuesday, September 26 |
| » Defeated Tigers (91-57), 3-1 | Tiger Stadium (4-7) | 57-91 | Won 3 |
| » Starters: Don Johnson vs Hal Newhouser | Seventh | 38½ out |
| » Lost to Tigers (92-57), 5-3 | Tiger Stadium (4-8) | 57-92 | |
| » Starters: Cliff Fannin vs Dizzy Trout | Seventh | 38½ out |
| Wednesday, September 27 |
| » Lost to Tigers (93-57), 5-4 | Tiger Stadium (4-9) | 57-93 | Lost 2 |
| » Starters: Dick Starr vs Art Houtteman | Seventh | 38½ out |
| Thursday, September 28 |
| » Lost to Tigers (94-57), 4-3 | Tiger Stadium (4-10) | 57-94 | Lost 3 |
| » Starters: Duane Pillette vs Fred Hutchinson | Seventh | 39½ out |
| Saturday, September 30 |
| » Lost to White Sox (59-93), 8-2 | Comiskey Park I (4-5) | 57-95 | Lost 4 |
| » Starters: Al Widmar vs Billy Pierce | Seventh | 40½ out |
| Sunday, October 1 |
| » Lost to White Sox (60-93), 4-3 | Comiskey Park I (4-6) | 57-96 | Lost 5 |
| » Starters: Ned Garver vs Bill Wight | Seventh | 40 out |
| » Defeated White Sox (60-94), 10-6 | Comiskey Park I (5-6) | 58-96 | |
| » Starters: Stubby Overmire vs Gus Keriazakos | Seventh | 40 out |
Game information provided by Retrosheet (www.retrosheet.org) |