| Saturday, February 12 |
| Future Senator Lenny Randle is born in Long Beach, CA. |
| Monday, April 18 |
| » Defeated Athletics (0-1), 3-2 | Griffith Stadium (1-0) | 1-0 | |
| » Starters: Dick Fowler vs Ray Scarborough | First | -- |
| Tuesday, April 19 |
| » Lost to Yankees (1-0), 3-2 | Yankee Stadium (0-1) | 1-1 | |
| » Starters: Sid Hudson vs Ed Lopat | Second | ½ out |
| » Major-league debuts: Dick Kryhoski (Yankees) |
| Wednesday, April 20 |
| » Lost to Yankees (2-0), 3-0 | Yankee Stadium (0-2) | 1-2 | Lost 2 |
| » Starters: Paul Calvert vs Vic Raschi | Fourth | 1½ out |
| » Major-league debuts: Jerry Coleman (Yankees) |
| Thursday, April 21 |
| » Lost to Yankees (3-0), 2-1 | Yankee Stadium (0-3) | 1-3 | Lost 3 |
| » Starters: Forrest Thompson vs Tommy Byrne | Fifth | 2½ out |
| Friday, April 22 |
| » Lost to Athletics (3-2), 2-0 | Griffith Stadium (1-1) | 1-4 | Lost 4 |
| » Starters: Carl Scheib vs Mickey Haefner | Sixth | 3½ out |
| Saturday, April 23 |
| » Lost to Athletics (4-2), 14-1 | Griffith Stadium (1-2) | 1-5 | Lost 5 |
| » Starters: Dick Fowler vs Ray Scarborough | Sixth | 3½ out |
| Sunday, April 24 |
| » Lost to Athletics (5-2), 8-3 | Griffith Stadium (1-3) | 1-6 | Lost 6 |
| » Starters: Lou Brissie vs Sid Hudson | Fifth | 4½ out |
| Monday, April 25 |
| » Lost to Red Sox (3-4), 2-0 | Fenway Park (0-1) | 1-7 | Lost 7 |
| » Starters: Paul Calvert vs Mel Parnell | Seventh | 5½ out |
| Wednesday, April 27 |
| » Defeated Yankees (7-2), 4-3 | Griffith Stadium (2-3) | 2-7 | |
| » Starters: Allie Reynolds vs Mickey Haefner | Sixth | 5 out |
| Thursday, April 28 |
| » Lost to Yankees (8-2), 6-2 | Griffith Stadium (2-4) | 2-8 | |
| » Starters: Ed Lopat vs Ray Scarborough | Seventh | 6 out |
| Friday, April 29 |
| » Lost to Athletics (6-6), 6-5 | Shibe Park (0-1) | 2-9 | Lost 2 |
| » Starters: Sid Hudson vs Lou Brissie | Sixth | 7 out |
| Saturday, April 30 |
| » Defeated Athletics (6-7), 4-3 | Shibe Park (1-1) | 3-9 | |
| » Starters: Paul Calvert vs Joe Coleman | Seventh | 7 out |
| Sunday, May 1 |
| » Lost to Athletics (7-7), 15-9 | Shibe Park (1-2) | 3-10 | |
| » Starters: Joe Haynes vs Carl Scheib | Eighth | 7½ out |
| » Lost to Athletics (8-7), 7-3 | Shibe Park (1-3) | 3-11 | Lost 2 |
| » Starters: Dick Weik vs Alex Kellner | Eighth | 7½ out |
| Tuesday, May 3 |
| » Defeated White Sox (8-6), 14-12 | Comiskey Park I (1-0) | 4-11 | |
| » Starters: Ray Scarborough vs Randy Gumpert | Seventh | 7½ out |
| Wednesday, May 4 |
| » Defeated White Sox (8-7), 8-7 | Comiskey Park I (2-0) | 5-11 | Won 2 |
| » Starters: Sid Hudson vs Marino Pieretti | Seventh | 7½ out |
| Thursday, May 5 |
| » Defeated Browns (3-13), 5-3 | Sportsman's Park III (1-0) | 6-11 | Won 3 |
| » Starters: Mickey Haefner vs Red Embree | Seventh | 7½ out |
| Friday, May 6 |
| » Defeated Browns (3-14), 8-7 | Sportsman's Park III (2-0) | 7-11 | Won 4 |
| » Starters: Paul Calvert vs Karl Drews | Seventh | 6½ out |
| Saturday, May 7 |
| » Defeated Browns (3-15), 6-4 | Sportsman's Park III (3-0) | 8-11 | Won 5 |
| » Starters: Walt Masterson vs Dick Starr | Sixth | 6½ out |
| Sunday, May 8 |
| » Defeated Indians (9-5), 7-3 | Cleveland Stadium (1-0) | 9-11 | Won 6 |
| » Starters: Ray Scarborough vs Gene Bearden | Fifth | 6 out |
| » Defeated Indians (9-6), 2-0 | Cleveland Stadium (2-0) | 10-11 | Won 7 |
| » Starters: Sid Hudson vs Al Benton | Fifth | 6 out |
| Tuesday, May 10 |
| » Defeated Indians (9-7), 1-0 | Cleveland Stadium (3-0) | 11-11 | Won 8 |
| » Starters: Mickey Haefner vs Steve Gromek | Fourth | 5½ out |
| Wednesday, May 11 |
| » Defeated Tigers (11-9), 11-1 | Tiger Stadium (1-0) | 12-11 | Won 9 |
| » Starters: Paul Calvert vs Stubby Overmire | Fourth | 4½ out |
| Thursday, May 12 |
| » Lost to Tigers (12-9), 2-1 | Tiger Stadium (1-1) | 12-12 | |
| » Starters: Walt Masterson vs Virgil Trucks | Fourth | 5 out |
| Saturday, May 14 |
| » Defeated Red Sox (9-12), 5-4 | Griffith Stadium (3-4) | 13-12 | |
| » Starters: Mickey Harris vs Ray Scarborough | Fourth | 4 out |
| Sunday, May 15 |
| » Lost to Red Sox (10-12), 3-0 | Griffith Stadium (3-5) | 13-13 | |
| » Starters: Joe Dobson vs Sid Hudson | Sixth | 3½ out |
| Monday, May 16 |
| » Defeated Red Sox (10-13), 3-2 | Griffith Stadium (4-5) | 14-13 | |
| » Starters: Jack Kramer vs Mickey Haefner | Fourth | 3 out |
| Tuesday, May 17 |
| » Lost to Tigers (15-11), 4-2 | Griffith Stadium (4-6) | 14-14 | |
| » Starters: Virgil Trucks vs Walt Masterson | Fifth | 4 out |
| Wednesday, May 18 |
| » Defeated Tigers (15-12), 6-3 | Griffith Stadium (5-6) | 15-14 | |
| » Starters: Ted Gray vs Paul Calvert | Third | 4 out |
| Thursday, May 19 |
| » Lost to Tigers (16-12), 10-1 | Griffith Stadium (5-7) | 15-15 | |
| » Starters: Fred Hutchinson vs Ray Scarborough | Fourth | 4 out |
| Friday, May 20 |
| » Defeated Browns (9-21), 5-3 | Griffith Stadium (6-7) | 16-15 | |
| » Starters: Al Papai vs Sid Hudson | Fifth | 3½ out |
| Saturday, May 21 |
| » Defeated Browns (9-22), 7-6 | Griffith Stadium (7-7) | 17-15 | Won 2 |
| » Starters: Red Embree vs Mickey Haefner | Fourth | 3½ out |
| Sunday, May 22 |
| » Lost to White Sox (16-15), 6-4 | Griffith Stadium (7-8) | 17-16 | |
| » Starters: Billy Pierce vs Walt Masterson | Fourth | 4 out |
| Monday, May 23 |
| » Lost to White Sox (17-15), 3-1 | Griffith Stadium (7-9) | 17-17 | Lost 2 |
| » Starters: Randy Gumpert vs Joe Haynes | Sixth | 5 out |
| Wednesday, May 25 |
| » Defeated Indians (12-16), 6-2 | Griffith Stadium (8-9) | 18-17 | |
| » Starters: Steve Gromek vs Sid Hudson | Fifth | 5½ out |
| Thursday, May 26 |
| » Defeated Indians (12-17), 5-4 | Griffith Stadium (9-9) | 19-17 | Won 2 |
| » Starters: Gene Bearden vs Mickey Haefner | Fourth | 5 out |
| Saturday, May 28 |
| » Lost to Red Sox (18-15), 5-4 | Fenway Park (0-2) | 19-18 | |
| » Starters: Ray Scarborough vs Jack Kramer | Fourth | 6½ out |
| Sunday, May 29 |
| » Defeated Red Sox (18-16), 10-4 | Fenway Park (1-2) | 20-18 | |
| » Starters: Paul Calvert vs Ellis Kinder | Fourth | 5½ out |
| » Major-league debuts: Frank Quinn (Red Sox) |
| Monday, May 30 |
| » Defeated Yankees (24-12), 6-2 | Griffith Stadium (10-9) | 21-18 | Won 2 |
| » Starters: Tommy Byrne vs Walt Masterson | Third | 5½ out |
| » Lost to Yankees (25-12), 13-3 | Griffith Stadium (10-10) | 21-19 | |
| » Starters: Allie Reynolds vs Sid Hudson | Third | 5½ out |
| Wednesday, June 1 |
| » Defeated Browns (10-31), 6-5 | Sportsman's Park III (4-0) | 22-19 | |
| » Starters: Mickey Haefner vs Red Embree | Third | 5½ out |
| Thursday, June 2 |
| » Defeated Browns (10-32), 4-1 | Sportsman's Park III (5-0) | 23-19 | Won 2 |
| » Starters: Ray Scarborough vs Dick Starr | Third | 5½ out |
| Friday, June 3 |
| » Defeated Browns (10-33), 12-3 | Sportsman's Park III (6-0) | 24-19 | Won 3 |
| » Starters: Paul Calvert vs Ned Garver | Second | 5½ out |
| Saturday, June 4 |
| » Lost to White Sox (20-23), 2-1 | Comiskey Park I (2-1) | 24-20 | |
| » Starters: Walt Masterson vs Bill Wight | Third | 6½ out |
| Sunday, June 5 |
| » Defeated White Sox (20-24), 7-6 | Comiskey Park I (3-1) | 25-20 | |
| » Starters: Joe Haynes vs Randy Gumpert | Third | 6½ out |
| » Lost to White Sox (21-24), 5-4 | Comiskey Park I (3-2) | 25-21 | |
| » Starters: Sid Hudson vs Al Gettel | Third | 6½ out |
| Tuesday, June 7 |
| » Lost to Indians (21-22), 13-11 | Cleveland Stadium (3-1) | 25-22 | Lost 2 |
| » Starters: Mickey Haefner vs Bob Lemon | Third | 6½ out |
| Wednesday, June 8 |
| » Lost to Indians (22-22), 8-3 | Cleveland Stadium (3-2) | 25-23 | Lost 3 |
| » Starters: Paul Calvert vs Bob Lemon | Fourth | 6½ out |
| Saturday, June 11 |
| » Defeated Tigers (28-22), 9-8 | Tiger Stadium (2-1) | 26-23 | |
| » Starters: Walt Masterson vs Fred Hutchinson | Fourth | 6½ out |
| Sunday, June 12 |
| » Lost to Tigers (29-22), 9-0 | Tiger Stadium (2-2) | 26-24 | |
| » Starters: Ray Scarborough vs Hal Newhouser | Fourth | 6½ out |
| » Lost to Tigers (30-22), 6-5 | Tiger Stadium (2-3) | 26-25 | Lost 2 |
| » Starters: Sid Hudson vs Lou Kretlow | Fourth | 6½ out |
| » Major-league debuts: Lloyd Hittle (Senators) |
| Tuesday, June 14 |
| » Lost to Browns (16-36), 7-2 | Griffith Stadium (10-11) | 26-26 | Lost 3 |
| » Starters: Joe Ostrowski vs Mickey Haefner | Sixth | 7½ out |
| Wednesday, June 15 |
| » Defeated Browns (16-37), 9-0 | Griffith Stadium (11-11) | 27-26 | |
| » Starters: Bill Kennedy vs Ray Scarborough | Fifth | 7½ out |
| Thursday, June 16 |
| » Defeated Browns (16-38), 5-0 | Griffith Stadium (12-11) | 28-26 | Won 2 |
| » Starters: Red Embree vs Sid Hudson | Fifth | 7 out |
| Sunday, June 19 |
| » Lost to Tigers (32-24), 9-0 | Griffith Stadium (12-12) | 28-27 | |
| » Starters: Virgil Trucks vs Paul Calvert | Sixth | 7½ out |
| » Lost to Tigers (33-24), 7-0 | Griffith Stadium (12-13) | 28-28 | Lost 2 |
| » Starters: Fred Hutchinson vs Mickey Harris | Sixth | 7½ out |
| Monday, June 20 |
| » Lost to White Sox (24-36), 5-4 | Griffith Stadium (12-14) | 28-29 | Lost 3 |
| » Starters: Bob Kuzava vs Ray Scarborough | Sixth | 8½ out |
| Tuesday, June 21 |
| » Defeated White Sox (24-37), 9-3 | Griffith Stadium (13-14) | 29-29 | |
| » Starters: Al Gettel vs Sid Hudson | Sixth | 8 out |
| Wednesday, June 22 |
| » Lost to White Sox (25-37), 4-1 | Griffith Stadium (13-15) | 29-30 | |
| » Starters: Bill Wight vs Lloyd Hittle | Sixth | 8½ out |
| Thursday, June 23 |
| » Lost to Indians (31-27), 4-3 | Griffith Stadium (13-16) | 29-31 | Lost 2 |
| » Starters: Early Wynn vs Paul Calvert | Sixth | 9½ out |
| Friday, June 24 |
| » Lost to Indians (32-27), 8-2 | Griffith Stadium (13-17) | 29-32 | Lost 3 |
| » Starters: Bob Feller vs Joe Haynes | Sixth | 10½ out |
| Saturday, June 25 |
| » Defeated Indians (32-28), 4-2 | Griffith Stadium (14-17) | 30-32 | |
| » Starters: Frank Papish vs Mickey Harris | Sixth | 9½ out |
| Sunday, June 26 |
| » Lost to Indians (33-28), 3-1 | Griffith Stadium (14-18) | 30-33 | |
| » Starters: Steve Gromek vs Sid Hudson | Sixth | 10 out |
| Tuesday, June 28 |
| » Lost to Athletics (38-29), 6-1 | Griffith Stadium (14-19) | 30-34 | Lost 2 |
| » Starters: Alex Kellner vs Mickey Haefner | Sixth | 11 out |
| Wednesday, June 29 |
| » Lost to Athletics (39-29), 7-4 | Griffith Stadium (14-20) | 30-35 | Lost 3 |
| » Starters: Carl Scheib vs Ray Scarborough | Sixth | 12 out |
| Thursday, June 30 |
| » Defeated Athletics (39-30), 8-6 | Griffith Stadium (15-20) | 31-35 | |
| » Starters: Dick Fowler vs Joe Haynes | Sixth | 12 out |
| Friday, July 1 |
| » Lost to Yankees (45-24), 5-4 | Griffith Stadium (15-21) | 31-36 | |
| » Starters: Ed Lopat vs Mickey Harris | Sixth | 13 out |
| Saturday, July 2 |
| » Lost to Yankees (46-24), 10-2 | Griffith Stadium (15-22) | 31-37 | Lost 2 |
| » Starters: Tommy Byrne vs Sid Hudson | Sixth | 14 out |
| Sunday, July 3 |
| » Defeated Yankees (46-25), 2-1 | Griffith Stadium (16-22) | 32-37 | |
| » Starters: Allie Reynolds vs Paul Calvert | Sixth | 13 out |
| Monday, July 4 |
| » Lost to Athletics (43-30), 9-7 | Shibe Park (1-4) | 32-38 | |
| » Starters: Ray Scarborough vs Carl Scheib | Sixth | 15 out |
| » Lost to Athletics (44-30), 8-0 | Shibe Park (1-5) | 32-39 | Lost 2 |
| » Starters: Dick Weik vs Bobby Shantz | Sixth | 15 out |
| Wednesday, July 6 |
| » Lost to Red Sox (37-36), 5-0 | Griffith Stadium (16-23) | 32-40 | Lost 3 |
| » Starters: Ellis Kinder vs Joe Haynes | Sixth | 15 out |
| Thursday, July 7 |
| » Game at Griffith Stadium interrupted in the 7th inning with the score of Red Sox 8, Senators 3. Completed on August 20. |
| Friday, July 8 |
| » Lost to Yankees (50-26), 4-3 | Yankee Stadium (0-4) | 32-41 | Lost 4 |
| » Starters: Mickey Harris vs Cuddles Marshall | Sixth | 16½ out |
| Saturday, July 9 |
| » Defeated Yankees (50-27), 7-5 | Yankee Stadium (1-4) | 33-41 | |
| » Starters: Paul Calvert vs Vic Raschi | Sixth | 15½ out |
| Thursday, July 14 |
| » Lost to White Sox (34-47), 6-2 | Comiskey Park I (3-3) | 33-42 | |
| » Starters: Sid Hudson vs Billy Pierce | Sixth | 16½ out |
| Friday, July 15 |
| » Defeated White Sox (34-48), 9-4 | Comiskey Park I (4-3) | 34-42 | |
| » Starters: Mickey Harris vs Bill Wight | Sixth | 16½ out |
| Saturday, July 16 |
| » Lost to White Sox (35-48), 5-1 | Comiskey Park I (4-4) | 34-43 | |
| » Starters: Ray Scarborough vs Bob Kuzava | Sixth | 16½ out |
| Sunday, July 17 |
| » Lost to Browns (26-55), 15-8 | Sportsman's Park III (6-1) | 34-44 | Lost 2 |
| » Starters: Joe Haynes vs Bill Kennedy | Sixth | 17½ out |
| » Lost to Browns (27-55), 7-4 | Sportsman's Park III (6-2) | 34-45 | Lost 3 |
| » Starters: Paul Calvert vs Cliff Fannin | Sixth | 17½ out |
| Former Senator Jack Slattery dies in Boston, MA at the age of 72. |
| Tuesday, July 19 |
| » Lost to Tigers (45-42), 7-6 | Tiger Stadium (2-4) | 34-46 | Lost 4 |
| » Starters: Lloyd Hittle vs Hal Newhouser | Sixth | 17 out |
| Wednesday, July 20 |
| » Lost to Tigers (46-42), 6-5 | Tiger Stadium (2-5) | 34-47 | Lost 5 |
| » Starters: Mickey Harris vs Lou Kretlow | Seventh | 18 out |
| Thursday, July 21 |
| » Lost to Tigers (47-42), 6-3 | Tiger Stadium (2-6) | 34-48 | Lost 6 |
| » Starters: Ray Scarborough vs Ted Gray | Sixth | 19 out |
| Friday, July 22 |
| » Lost to Indians (50-36), 2-1 | Cleveland Stadium (3-3) | 34-49 | Lost 7 |
| » Starters: Paul Calvert vs Mike Garcia | Sixth | 20 out |
| Saturday, July 23 |
| » Lost to Indians (51-36), 5-3 | Cleveland Stadium (3-4) | 34-50 | Lost 8 |
| » Starters: Joe Haynes vs Bob Feller | Seventh | 20 out |
| Sunday, July 24 |
| » Lost to Indians (52-36), 7-5 | Cleveland Stadium (3-5) | 34-51 | Lost 9 |
| » Starters: Al Gettel vs Bob Lemon | Seventh | 21½ out |
| » Lost to Indians (53-36), 5-2 | Cleveland Stadium (3-6) | 34-52 | Lost 10 |
| » Starters: Mickey Harris vs Gene Bearden | Seventh | 21½ out |
| Tuesday, July 26 |
| » Lost to Tigers (49-44), 6-2 | Griffith Stadium (16-24) | 34-53 | Lost 11 |
| » Starters: Ted Gray vs Paul Calvert | Seventh | 21½ out |
| Wednesday, July 27 |
| » Defeated Tigers (49-45), 7-6 | Griffith Stadium (17-24) | 35-53 | |
| » Starters: Lou Kretlow vs Sid Hudson | Seventh | 21½ out |
| » Lost to Tigers (50-45), 11-0 | Griffith Stadium (17-25) | 35-54 | |
| » Starters: Fred Hutchinson vs Joe Haynes | Seventh | 21½ out |
| Thursday, July 28 |
| » Lost to Tigers (51-45), 13-7 | Griffith Stadium (17-26) | 35-55 | Lost 2 |
| » Starters: Hal Newhouser vs Mickey Harris | Seventh | 22½ out |
| Friday, July 29 |
| » Lost to Browns (32-62), 6-2 | Griffith Stadium (17-27) | 35-56 | Lost 3 |
| » Starters: Ned Garver vs Dick Weik | Seventh | 23½ out |
| Saturday, July 30 |
| » Lost to Browns (33-62), 11-9 | Griffith Stadium (17-28) | 35-57 | Lost 4 |
| » Starters: Bill Kennedy vs Paul Calvert | Seventh | 23½ out |
| Sunday, July 31 |
| » Defeated Browns (33-63), 7-3 | Griffith Stadium (18-28) | 36-57 | |
| » Starters: Cliff Fannin vs Sid Hudson | Seventh | 23 out |
| Monday, August 1 |
| » Lost to Browns (34-63), 2-0 | Griffith Stadium (18-29) | 36-58 | |
| » Starters: Karl Drews vs Ray Scarborough | Seventh | 23½ out |
| Tuesday, August 2 |
| » Lost to Indians (57-40), 8-1 | Griffith Stadium (18-30) | 36-59 | Lost 2 |
| » Starters: Early Wynn vs Mickey Harris | Seventh | 23½ out |
| Wednesday, August 3 |
| » Major-league debuts: Mike Goliat (Phillies) |
| Thursday, August 4 |
| » Lost to Indians (58-40), 6-3 | Griffith Stadium (18-31) | 36-60 | Lost 3 |
| » Starters: Frank Papish vs Dick Weik | Seventh | 24½ out |
| » Lost to Indians (59-40), 14-1 | Griffith Stadium (18-32) | 36-61 | Lost 4 |
| » Starters: Bob Feller vs Paul Calvert | Seventh | 24½ out |
| Friday, August 5 |
| » Lost to White Sox (42-59), 4-1 | Griffith Stadium (18-33) | 36-62 | Lost 5 |
| » Starters: Mickey Haefner vs Sid Hudson | Seventh | 26 out |
| Saturday, August 6 |
| » Lost to White Sox (43-59), 6-5 | Griffith Stadium (18-34) | 36-63 | Lost 6 |
| » Starters: Bob Kuzava vs Ray Scarborough | Seventh | 27 out |
| Sunday, August 7 |
| » Lost to White Sox (44-59), 4-1 | Griffith Stadium (18-35) | 36-64 | Lost 7 |
| » Starters: Randy Gumpert vs Mickey Harris | Seventh | 27½ out |
| » Defeated White Sox (44-60), 1-0 | Griffith Stadium (19-35) | 37-64 | |
| » Starters: Billy Pierce vs Lloyd Hittle | Seventh | 27½ out |
| Tuesday, August 9 |
| » Lost to Athletics (59-47), 8-3 | Griffith Stadium (19-36) | 37-65 | |
| » Starters: Carl Scheib vs Dick Weik | Seventh | 27½ out |
| » Major-league debuts: Julio Gonzalez (Senators) |
| Wednesday, August 10 |
| » Defeated Athletics (59-48), 8-7 | Griffith Stadium (20-36) | 38-65 | |
| » Starters: Alex Kellner vs Sid Hudson | Seventh | 27½ out |
| Friday, August 12 |
| » Lost to Red Sox (62-45), 15-7 | Fenway Park (1-3) | 38-66 | |
| » Starters: Ray Scarborough vs Chuck Stobbs | Seventh | 28½ out |
| » Lost to Red Sox (63-45), 13-11 | Fenway Park (1-4) | 38-67 | Lost 2 |
| » Starters: Lloyd Hittle vs Mickey McDermott | Seventh | 28½ out |
| Saturday, August 13 |
| » Lost to Red Sox (64-45), 5-1 | Fenway Park (1-5) | 38-68 | Lost 3 |
| » Starters: Mickey Harris vs Ellis Kinder | Seventh | 29½ out |
| Sunday, August 14 |
| » Lost to Red Sox (65-45), 9-3 | Fenway Park (1-6) | 38-69 | Lost 4 |
| » Starters: Dick Weik vs Mel Parnell | Seventh | 30½ out |
| » Lost to Red Sox (66-45), 13-4 | Fenway Park (1-7) | 38-70 | Lost 5 |
| » Starters: Paul Calvert vs Jack Kramer | Seventh | 30½ out |
| Monday, August 15 |
| » Lost to Red Sox (67-45), 3-2 | Fenway Park (1-8) | 38-71 | Lost 6 |
| » Starters: Sid Hudson vs Joe Dobson | Seventh | 30½ out |
| Wednesday, August 17 |
| » Lost to Yankees (70-41), 4-3 | Yankee Stadium (1-5) | 38-72 | Lost 7 |
| » Starters: Ray Scarborough vs Vic Raschi | Seventh | 31½ out |
| Thursday, August 18 |
| » Lost to Yankees (71-41), 5-4 | Yankee Stadium (1-6) | 38-73 | Lost 8 |
| » Starters: Mickey Harris vs Tommy Byrne | Seventh | 32½ out |
| Friday, August 19 |
| » Lost to Red Sox (69-46), 6-0 | Griffith Stadium (20-37) | 38-74 | Lost 9 |
| » Starters: Ellis Kinder vs Dick Weik | Seventh | 33½ out |
| Saturday, August 20 |
| » Lost to Red Sox (70-46), 7-1 | Griffith Stadium (20-38) | 38-75 | Lost 10 |
| » Starters: Mel Parnell vs Paul Calvert | Seventh | 35 out |
| » Lost to Red Sox (71-46), 8-4 | Griffith Stadium (20-39) | 38-76 | Lost 11 |
| » Starters: Chuck Stobbs vs Mickey Haefner | Seventh | 35 out |
| Sunday, August 21 |
| » Lost to Red Sox (72-46), 4-0 | Griffith Stadium (20-40) | 38-77 | Lost 12 |
| » Starters: Jack Kramer vs Sid Hudson | Eighth | 35 out |
| Tuesday, August 23 |
| » Defeated Indians (69-49), 4-2 | Cleveland Stadium (4-6) | 39-77 | |
| » Starters: Ray Scarborough vs Bob Lemon | Eighth | 34 out |
| Wednesday, August 24 |
| » Defeated Indians (69-50), 3-2 | Cleveland Stadium (5-6) | 40-77 | Won 2 |
| » Starters: Mickey Harris vs Mike Garcia | Seventh | 33 out |
| Thursday, August 25 |
| » Lost to Tigers (68-56), 2-1 | Tiger Stadium (2-7) | 40-78 | |
| » Starters: Lloyd Hittle vs Virgil Trucks | Seventh | 34 out |
| Friday, August 26 |
| » Lost to Tigers (69-56), 11-1 | Tiger Stadium (2-8) | 40-79 | Lost 2 |
| » Starters: Sid Hudson vs Ted Gray | Eighth | 34 out |
| Saturday, August 27 |
| » Lost to Tigers (70-56), 7-6 | Tiger Stadium (2-9) | 40-80 | Lost 3 |
| » Starters: Joe Haynes vs Hal Newhouser | Eighth | 35 out |
| Sunday, August 28 |
| » Defeated Browns (43-82), 13-2 | Sportsman's Park III (7-2) | 41-80 | |
| » Starters: Ray Scarborough vs Karl Drews | Eighth | 36 out |
| » Lost to Browns (44-82), 4-3 | Sportsman's Park III (7-3) | 41-81 | |
| » Starters: Dick Weik vs Bill Kennedy | Eighth | 36 out |
| Monday, August 29 |
| » Lost to Browns (45-82), 2-1 | Sportsman's Park III (7-4) | 41-82 | Lost 2 |
| » Starters: Mickey Harris vs Cliff Fannin | Eighth | 36½ out |
| Tuesday, August 30 |
| » Defeated White Sox (51-75), 1-0 | Comiskey Park I (5-4) | 42-82 | |
| » Starters: Lloyd Hittle vs Bill Wight | Eighth | 35½ out |
| Wednesday, August 31 |
| » Lost to White Sox (52-75), 4-2 | Comiskey Park I (5-5) | 42-83 | |
| » Starters: Sid Hudson vs Billy Pierce | Eighth | 35½ out |
| Thursday, September 1 |
| » Lost to White Sox (53-75), 3-0 | Comiskey Park I (5-6) | 42-84 | Lost 2 |
| » Starters: Dick Weik vs Randy Gumpert | Eighth | 36½ out |
| Saturday, September 3 |
| » Lost to Yankees (79-47), 6-0 | Griffith Stadium (20-41) | 42-85 | Lost 3 |
| » Starters: Allie Reynolds vs Ray Scarborough | Eighth | 37½ out |
| Sunday, September 4 |
| » Defeated Yankees (79-48), 3-2 | Griffith Stadium (21-41) | 43-85 | |
| » Starters: Ed Lopat vs Mickey Harris | Eighth | 36½ out |
| Monday, September 5 |
| » Lost to Red Sox (81-52), 5-2 | Fenway Park (1-9) | 43-86 | |
| » Starters: Sid Hudson vs Mel Parnell | Eighth | 38½ out |
| » Lost to Red Sox (82-52), 12-2 | Fenway Park (1-10) | 43-87 | Lost 2 |
| » Starters: Lloyd Hittle vs Walt Masterson | Eighth | 38½ out |
| Tuesday, September 6 |
| Future Senator Mike Thompson is born in Denver, CO. |
| Thursday, September 8 |
| » Lost to Athletics (68-65), 9-1 | Shibe Park (1-6) | 43-88 | Lost 3 |
| » Starters: Jim Pearce vs Alex Kellner | Eighth | 40 out |
| » Lost to Athletics (69-65), 8-4 | Shibe Park (1-7) | 43-89 | Lost 4 |
| » Starters: Dick Weik vs Lou Brissie | Eighth | 40 out |
| Friday, September 9 |
| » Lost to Athletics (70-65), 5-2 | Shibe Park (1-8) | 43-90 | Lost 5 |
| » Starters: Lloyd Hittle vs Bobby Shantz | Eighth | 40 out |
| Saturday, September 10 |
| » Defeated Yankees (82-50), 4-3 | Yankee Stadium (2-6) | 44-90 | |
| » Starters: Ray Scarborough vs Vic Raschi | Eighth | 40 out |
| » Lost to Yankees (83-50), 8-1 | Yankee Stadium (2-7) | 44-91 | |
| » Starters: Mickey Harris vs Tommy Byrne | Eighth | 40 out |
| Sunday, September 11 |
| » Lost to Yankees (84-50), 20-5 | Yankee Stadium (2-8) | 44-92 | Lost 2 |
| » Starters: Paul Calvert vs Allie Reynolds | Eighth | 42 out |
| » Lost to Yankees (85-50), 2-1 | Yankee Stadium (2-9) | 44-93 | Lost 3 |
| » Starters: Sid Hudson vs Fred Sanford | Eighth | 42 out |
| Tuesday, September 13 |
| » Lost to White Sox (56-82), 3-2 | Griffith Stadium (21-42) | 44-94 | Lost 4 |
| » Starters: Randy Gumpert vs Dick Weik | Eighth | 42½ out |
| » Major-league debuts: Hal Keller (Senators) |
| Former Senator Tim Jordan dies in Bronx, NY at the age of 71. |
| Wednesday, September 14 |
| » Lost to White Sox (57-82), 8-1 | Griffith Stadium (21-43) | 44-95 | Lost 5 |
| » Starters: Bob Kuzava vs Lloyd Hittle | Eighth | 44 out |
| » Major-league debuts: Jim Baumer (White Sox) |
| Friday, September 16 |
| » Defeated Indians (81-59), 5-4 | Griffith Stadium (22-43) | 45-95 | |
| » Starters: Mike Garcia vs Ray Scarborough | Eighth | 43½ out |
| Saturday, September 17 |
| » Lost to Indians (82-59), 8-3 | Griffith Stadium (22-44) | 45-96 | |
| » Starters: Gene Bearden vs Mickey Harris | Eighth | 44½ out |
| Sunday, September 18 |
| » Lost to Tigers (83-62), 3-2 | Griffith Stadium (22-45) | 45-97 | Lost 2 |
| » Starters: Hal Newhouser vs Paul Calvert | Eighth | 46 out |
| » Lost to Tigers (84-62), 5-2 | Griffith Stadium (22-46) | 45-98 | Lost 3 |
| » Starters: Virgil Trucks vs Sid Hudson | Eighth | 46 out |
| Tuesday, September 20 |
| » Lost to Browns (50-97), 15-6 | Griffith Stadium (22-47) | 45-99 | Lost 4 |
| » Starters: Joe Ostrowski vs Dizzy Sutherland | Eighth | 47½ out |
| Wednesday, September 21 |
| » Defeated Browns (50-98), 7-0 | Griffith Stadium (23-47) | 46-99 | |
| » Starters: Cliff Fannin vs Dick Weik | Eighth | 46½ out |
| Friday, September 23 |
| » Defeated Yankees (92-53), 9-8 | Griffith Stadium (24-47) | 47-99 | Won 2 |
| » Starters: Vic Raschi vs Ray Scarborough | Eighth | 46½ out |
| » Lost to Yankees (93-53), 7-1 | Griffith Stadium (24-48) | 47-100 | |
| » Starters: Fred Sanford vs Mickey Harris | Eighth | 46½ out |
| » Major-league debuts: Wally Hood (Yankees) |
| Sunday, September 25 |
| » Lost to Athletics (79-69), 8-5 | Shibe Park (1-9) | 47-101 | Lost 2 |
| » Starters: Dick Welteroth vs Alex Kellner | Seventh | 45½ out |
| » Defeated Athletics (79-70), 4-0 | Shibe Park (2-9) | 48-101 | |
| » Starters: Dick Weik vs Lou Brissie | Seventh | 45½ out |
| Tuesday, September 27 |
| » Lost to Red Sox (95-55), 6-4 | Griffith Stadium (24-49) | 48-102 | |
| » Starters: Joe Dobson vs Paul Calvert | Eighth | 47 out |
| Wednesday, September 28 |
| » Defeated Red Sox (95-56), 2-1 | Griffith Stadium (25-49) | 49-102 | |
| » Starters: Chuck Stobbs vs Ray Scarborough | Seventh | 46 out |
| Friday, September 30 |
| » Lost to Red Sox (96-56), 11-9 | Griffith Stadium (25-50) | 49-103 | |
| » Starters: Jack Kramer vs Mickey Harris | Seventh | 47 out |
| Saturday, October 1 |
| » Lost to Athletics (81-72), 7-4 | Griffith Stadium (25-51) | 49-104 | Lost 2 |
| » Starters: Alex Kellner vs Dick Welteroth | Seventh | 47 out |
| Sunday, October 2 |
| » Defeated Athletics (81-73), 3-0 | Griffith Stadium (26-51) | 50-104 | |
| » Starters: Lou Brissie vs Dick Weik | Eighth | 47 out |
Game information provided by Retrosheet (www.retrosheet.org) |
