| Monday, January 3 |
| Future Giant Gary Lavelle is born in Scranton, PA. |
| Tuesday, January 4 |
| Former Giant Joe Evers dies in Albany, NY at the age of 58. |
| Saturday, January 22 |
| Future Giant Mike Caldwell is born in Tarboro, NC. |
| Monday, January 31 |
| Future Giant Jim Willoughby is born in Salinas, CA. |
| Friday, February 18 |
| Former Giant Marty O'Toole dies in Aberdeen, WA at the age of 61. |
| Tuesday, April 19 |
| » Lost to Dodgers (1-0), 10-3 | Ebbets Field (0-1) | 0-1 | |
| » Starters: Larry Jansen vs Joe Hatten | Fourth | 1 out |
| » Major-league debuts: Bobby Hofman (Giants) |
| Wednesday, April 20 |
| » Lost to Dodgers (2-0), 6-2 | Ebbets Field (0-2) | 0-2 | Lost 2 |
| » Starters: Sheldon Jones vs Ralph Branca | Seventh | 2 out |
| » Major-league debuts: Cal Abrams (Dodgers) |
| Thursday, April 21 |
| » Defeated Dodgers (2-1), 4-1 | Ebbets Field (1-2) | 1-2 | |
| » Starters: Clint Hartung vs Preacher Roe | Fourth | 1½ out |
| Friday, April 22 |
| » Tied Braves, 6-6 | Polo Grounds V (0-0) | 1-2 | |
| » Starters: Johnny Sain vs Larry Jansen | Fourth | 1½ out |
| Saturday, April 23 |
| » Defeated Braves (3-2), 11-3 | Polo Grounds V (1-0) | 2-2 | Won 2 |
| » Starters: Warren Spahn vs Monte Kennedy | Fourth | 1 out |
| » Major-league debuts: Bob Hall (Braves) |
| Sunday, April 24 |
| » Defeated Braves (3-3), 6-2 | Polo Grounds V (2-0) | 3-2 | Won 3 |
| » Starters: Vern Bickford vs Sheldon Jones | Second | ½ out |
| » Major-league debuts: Don Thompson (Braves) |
| Monday, April 25 |
| » Defeated Phillies (2-6), 6-3 | Shibe Park (1-0) | 4-2 | Won 4 |
| » Starters: Clint Hartung vs Hank Borowy | First | -- |
| Tuesday, April 26 |
| » Lost to Phillies (3-6), 12-11 | Shibe Park (1-1) | 4-3 | |
| » Starters: Larry Jansen vs Russ Meyer | Second | ½ out |
| Wednesday, April 27 |
| » Defeated Dodgers (5-4), 11-8 | Polo Grounds V (3-0) | 5-3 | |
| » Starters: Paul Minner vs Monte Kennedy | First | -- |
| Thursday, April 28 |
| » Lost to Dodgers (6-4), 15-2 | Polo Grounds V (3-1) | 5-4 | |
| » Starters: Ralph Branca vs Sheldon Jones | Second | ½ out |
| Friday, April 29 |
| » Defeated Braves (6-5), 10-9 | Braves Field (1-0) | 6-4 | |
| » Starters: Clint Hartung vs Bill Voiselle | First | -- |
| Saturday, April 30 |
| » Lost to Braves (7-5), 4-0 | Braves Field (1-1) | 6-5 | |
| » Starters: Larry Jansen vs Johnny Sain | Third | ½ out |
| Future Giant Phil Garner is born in Jefferson City, TN. |
| Sunday, May 1 |
| » Lost to Braves (8-5), 6-5 | Braves Field (1-2) | 6-6 | Lost 2 |
| » Starters: Monte Kennedy vs Warren Spahn | Fourth | 2½ out |
| » Lost to Braves (9-5), 4-2 | Braves Field (1-3) | 6-7 | Lost 3 |
| » Starters: Sheldon Jones vs Johnny Antonelli | Fourth | 2½ out |
| Tuesday, May 3 |
| » Defeated Pirates (6-8), 5-3 | Polo Grounds V (4-1) | 7-7 | |
| » Starters: Murry Dickson vs Clint Hartung | Fourth | 1½ out |
| Wednesday, May 4 |
| » Defeated Pirates (6-9), 11-4 | Polo Grounds V (5-1) | 8-7 | Won 2 |
| » Starters: Bob Muncrief vs Larry Jansen | Second | 1½ out |
| Thursday, May 5 |
| » Defeated Pirates (6-10), 3-2 | Polo Grounds V (6-1) | 9-7 | Won 3 |
| » Starters: Rip Sewell vs Sheldon Jones | Second | 1 out |
| Friday, May 6 |
| » Defeated Cardinals (7-8), 3-0 | Polo Grounds V (7-1) | 10-7 | Won 4 |
| » Starters: Jim Hearn vs Monte Kennedy | Second | 1 out |
| Saturday, May 7 |
| » Defeated Cardinals (7-9), 9-1 | Polo Grounds V (8-1) | 11-7 | Won 5 |
| » Starters: Harry Brecheen vs Clint Hartung | First | -- |
| Sunday, May 8 |
| » Defeated Cubs (7-10), 10-1 | Polo Grounds V (9-1) | 12-7 | Won 6 |
| » Starters: Monk Dubiel vs Larry Jansen | First | -- |
| Monday, May 9 |
| » Defeated Cubs (7-11), 7-2 | Polo Grounds V (10-1) | 13-7 | Won 7 |
| » Starters: Ralph Hamner vs Sheldon Jones | First | -- |
| Wednesday, May 11 |
| » Lost to Reds (10-10), 4-2 | Polo Grounds V (10-2) | 13-8 | |
| » Starters: Howie Fox vs Monte Kennedy | First | -- |
| Future Giant Jerry Martin is born in Columbia, SC. |
| Thursday, May 12 |
| » Lost to Reds (11-10), 3-0 | Polo Grounds V (10-3) | 13-9 | Lost 2 |
| » Starters: Ken Raffensberger vs Clint Hartung | First | -- |
| Friday, May 13 |
| » Defeated Phillies (11-13), 9-1 | Polo Grounds V (11-3) | 14-9 | |
| » Starters: Russ Meyer vs Larry Jansen | First | -- |
| Saturday, May 14 |
| » Defeated Phillies (11-14), 12-2 | Polo Grounds V (12-3) | 15-9 | Won 2 |
| » Starters: Robin Roberts vs Sheldon Jones | First | -- |
| Sunday, May 15 |
| » Defeated Phillies (11-15), 7-3 | Polo Grounds V (13-3) | 16-9 | Won 3 |
| » Starters: Curt Simmons vs Monte Kennedy | First | -- |
| Monday, May 16 |
| Future Giant Rick Reuschel is born in Quincy, IL. |
| Tuesday, May 17 |
| » Lost to Pirates (12-15), 3-2 | Forbes Field (0-1) | 16-10 | |
| » Starters: Clint Hartung vs Bob Chesnes | First | -- |
| Wednesday, May 18 |
| » Lost to Pirates (13-15), 5-3 | Forbes Field (0-2) | 16-11 | Lost 2 |
| » Starters: Larry Jansen vs Bob Muncrief | First | -- |
| Thursday, May 19 |
| » Defeated Reds (15-13), 6-2 | Crosley Field (1-0) | 17-11 | |
| » Starters: Sheldon Jones vs Johnny Vander Meer | First | -- |
| Friday, May 20 |
| » Defeated Reds (15-14), 5-0 | Crosley Field (2-0) | 18-11 | Won 2 |
| » Starters: Monte Kennedy vs Howie Fox | First | -- |
| Sunday, May 22 |
| » Lost to Cardinals (12-16), 3-2 | Sportsman's Park III (0-1) | 18-12 | |
| » Starters: Clint Hartung vs Al Brazle | First | -- |
| » Defeated Cardinals (12-17), 13-4 | Sportsman's Park III (1-1) | 19-12 | |
| » Starters: Larry Jansen vs Bill Reeder | First | -- |
| Tuesday, May 24 |
| » Lost to Cubs (11-19), 8-2 | Wrigley Field (0-1) | 19-13 | |
| » Starters: Sheldon Jones vs Bob Chipman | Second | ½ out |
| Wednesday, May 25 |
| » Lost to Cubs (12-19), 3-2 | Wrigley Field (0-2) | 19-14 | Lost 2 |
| » Starters: Monte Kennedy vs Bob Rush | Second | ½ out |
| Friday, May 27 |
| » Lost to Phillies (16-17), 9-3 | Shibe Park (1-2) | 19-15 | Lost 3 |
| » Starters: Clint Hartung vs Curt Simmons | Second | ½ out |
| Saturday, May 28 |
| » Lost to Phillies (17-17), 5-2 | Shibe Park (1-3) | 19-16 | Lost 4 |
| » Starters: Larry Jansen vs Hank Borowy | Third | 1½ out |
| Sunday, May 29 |
| » Defeated Phillies (17-18), 4-2 | Shibe Park (2-3) | 20-16 | |
| » Starters: Sheldon Jones vs Robin Roberts | First | -- |
| » Defeated Phillies (17-19), 3-0 | Shibe Park (3-3) | 21-16 | Won 2 |
| » Starters: Hank Behrman vs Russ Meyer | First | -- |
| Monday, May 30 |
| » Lost to Dodgers (22-16), 2-1 | Polo Grounds V (13-4) | 21-17 | |
| » Starters: Rex Barney vs Monte Kennedy | First | -- |
| » Defeated Dodgers (22-17), 7-4 | Polo Grounds V (14-4) | 22-17 | |
| » Starters: Ralph Branca vs Clint Hartung | First | -- |
| Tuesday, May 31 |
| » Lost to Dodgers (23-17), 6-4 | Polo Grounds V (14-5) | 22-18 | |
| » Starters: Morrie Martin vs Larry Jansen | Second | 1 out |
| Wednesday, June 1 |
| » Defeated Cubs (15-23), 11-5 | Polo Grounds V (15-5) | 23-18 | |
| » Starters: Johnny Schmitz vs Andy Hansen | Second | 1 out |
| Thursday, June 2 |
| » Lost to Cubs (16-23), 3-0 | Polo Grounds V (15-6) | 23-19 | |
| » Starters: Dutch Leonard vs Sheldon Jones | Second | 2 out |
| Friday, June 3 |
| » Defeated Cubs (16-24), 15-5 | Polo Grounds V (16-6) | 24-19 | |
| » Starters: Bob Chipman vs Monte Kennedy | Second | 1½ out |
| Saturday, June 4 |
| » Defeated Reds (21-23), 9-3 | Polo Grounds V (17-6) | 25-19 | Won 2 |
| » Starters: Herm Wehmeier vs Clint Hartung | Second | ½ out |
| Sunday, June 5 |
| » Defeated Reds (21-24), 6-1 | Polo Grounds V (18-6) | 26-19 | Won 3 |
| » Starters: Johnny Vander Meer vs Larry Jansen | First | -- |
| Monday, June 6 |
| » Lost to Reds (22-24), 4-3 | Polo Grounds V (18-7) | 26-20 | |
| » Starters: Howie Fox vs Sheldon Jones | First | -- |
| Tuesday, June 7 |
| » Lost to Cardinals (25-19), 3-0 | Polo Grounds V (18-8) | 26-21 | Lost 2 |
| » Starters: Harry Brecheen vs Monte Kennedy | Fourth | 1 out |
| Former Giant Hi Bell dies in Glendale, CA at the age of 52. |
| Wednesday, June 8 |
| » Lost to Cardinals (26-19), 2-0 | Polo Grounds V (18-9) | 26-22 | Lost 3 |
| » Starters: Gerry Staley vs Dave Koslo | Fourth | 2 out |
| Thursday, June 9 |
| » Lost to Cardinals (27-19), 4-1 | Polo Grounds V (18-10) | 26-23 | Lost 4 |
| » Starters: Howie Pollet vs Clint Hartung | Fourth | 3 out |
| Friday, June 10 |
| » Lost to Pirates (18-31), 6-1 | Polo Grounds V (18-11) | 26-24 | Lost 5 |
| » Starters: Bill Werle vs Larry Jansen | Fifth | 4 out |
| Saturday, June 11 |
| » Defeated Pirates (18-32), 4-3 | Polo Grounds V (19-11) | 27-24 | |
| » Starters: Elmer Riddle vs Monte Kennedy | Fourth | 4 out |
| Sunday, June 12 |
| » Lost to Pirates (19-32), 6-5 | Polo Grounds V (19-12) | 27-25 | |
| » Starters: Vic Lombardi vs Kirby Higbe | Fifth | 5 out |
| Tuesday, June 14 |
| » Defeated Reds (22-31), 2-0 | Crosley Field (3-0) | 28-25 | |
| » Starters: Larry Jansen vs Eddie Erautt | Fifth | 5 out |
| Wednesday, June 15 |
| Future Giant Dusty Baker is born in Riverside, CA. |
| Friday, June 17 |
| » Lost to Pirates (22-33), 6-4 | Forbes Field (0-3) | 28-26 | |
| » Starters: Clint Hartung vs Tiny Bonham | Fifth | 5 out |
| Saturday, June 18 |
| » Defeated Pirates (22-34), 5-4 | Forbes Field (1-3) | 29-26 | |
| » Starters: Sheldon Jones vs Elmer Riddle | Fifth | 5 out |
| Sunday, June 19 |
| » Lost to Pirates (23-34), 9-4 | Forbes Field (1-4) | 29-27 | |
| » Starters: Larry Jansen vs Bob Chesnes | Fifth | 5 out |
| Monday, June 20 |
| » Lost to Cardinals (34-23), 7-2 | Sportsman's Park III (1-2) | 29-28 | Lost 2 |
| » Starters: Monte Kennedy vs Gerry Staley | Fifth | 5½ out |
| Tuesday, June 21 |
| » Defeated Cardinals (34-24), 6-5 | Sportsman's Park III (2-2) | 30-28 | |
| » Starters: Dave Koslo vs Red Munger | Fifth | 5½ out |
| Wednesday, June 22 |
| » Lost to Cardinals (35-24), 11-8 | Sportsman's Park III (2-3) | 30-29 | |
| » Starters: Sheldon Jones vs Harry Brecheen | Fifth | 5½ out |
| Thursday, June 23 |
| » Lost to Cardinals (36-24), 10-6 | Sportsman's Park III (2-4) | 30-30 | Lost 2 |
| » Starters: Clint Hartung vs Howie Pollet | Fifth | 6½ out |
| Friday, June 24 |
| » Lost to Cubs (23-39), 6-2 | Wrigley Field (0-3) | 30-31 | Lost 3 |
| » Starters: Larry Jansen vs Warren Hacker | Fifth | 7 out |
| Saturday, June 25 |
| » Lost to Cubs (24-39), 4-1 | Wrigley Field (0-4) | 30-32 | Lost 4 |
| » Starters: Monte Kennedy vs Bob Rush | Fifth | 7½ out |
| Sunday, June 26 |
| » Defeated Cubs (24-40), 6-2 | Wrigley Field (1-4) | 31-32 | |
| » Starters: Dave Koslo vs Dutch Leonard | Fifth | 7½ out |
| Tuesday, June 28 |
| » Defeated Braves (36-31), 2-1 | Polo Grounds V (20-12) | 32-32 | Won 2 |
| » Starters: Warren Spahn vs Clint Hartung | Fifth | 7½ out |
| Wednesday, June 29 |
| » Defeated Braves (36-32), 9-3 | Polo Grounds V (21-12) | 33-32 | Won 3 |
| » Starters: Vern Bickford vs Larry Jansen | Fifth | 7½ out |
| Thursday, June 30 |
| » Lost to Braves (37-32), 3-0 | Polo Grounds V (21-13) | 33-33 | |
| » Starters: Bill Voiselle vs Hank Behrman | Fourth | 8 out |
| » Lost to Braves (38-32), 6-2 | Polo Grounds V (21-14) | 33-34 | Lost 2 |
| » Starters: Glenn Elliott vs Sheldon Jones | Fourth | 8 out |
| Friday, July 1 |
| » Defeated Dodgers (41-27), 4-1 | Polo Grounds V (22-14) | 34-34 | |
| » Starters: Don Newcombe vs Dave Koslo | Fifth | 7 out |
| Saturday, July 2 |
| » Lost to Dodgers (42-27), 13-8 | Polo Grounds V (22-15) | 34-35 | |
| » Starters: Rex Barney vs Clint Hartung | Fourth | 8 out |
| Sunday, July 3 |
| » Defeated Dodgers (42-28), 16-0 | Polo Grounds V (23-15) | 35-35 | |
| » Starters: Ralph Branca vs Monte Kennedy | Fifth | 7 out |
| Monday, July 4 |
| » Defeated Braves (39-35), 11-4 | Braves Field (2-3) | 36-35 | Won 2 |
| » Starters: Larry Jansen vs Bill Voiselle | Fourth | 8 out |
| » Lost to Braves (40-35), 8-7 | Braves Field (2-4) | 36-36 | |
| » Starters: Clint Hartung vs Glenn Elliott | Fourth | 8 out |
| Thursday, July 7 |
| » Defeated Phillies (41-36), 11-3 | Polo Grounds V (24-15) | 37-36 | |
| » Starters: Hank Borowy vs Dave Koslo | Fourth | 7 out |
| Friday, July 8 |
| » Lost to Dodgers (46-30), 4-3 | Ebbets Field (1-3) | 37-37 | |
| » Starters: Clint Hartung vs Don Newcombe | Fifth | 8 out |
| » Major-league debuts: Monte Irvin (Giants) |
| Saturday, July 9 |
| » Defeated Dodgers (46-31), 9-5 | Ebbets Field (2-3) | 38-37 | |
| » Starters: Monte Kennedy vs Jack Banta | Fifth | 7 out |
| Sunday, July 10 |
| » Lost to Dodgers (47-31), 7-3 | Ebbets Field (2-4) | 38-38 | |
| » Starters: Sheldon Jones vs Preacher Roe | Fifth | 8 out |
| Thursday, July 14 |
| » Defeated Pirates (35-43), 4-3 | Polo Grounds V (25-15) | 39-38 | |
| » Starters: Bill Werle vs Larry Jansen | Fifth | 8 out |
| Saturday, July 16 |
| » Lost to Pirates (36-43), 9-0 | Polo Grounds V (25-16) | 39-39 | |
| » Starters: Bob Chesnes vs Clint Hartung | Fifth | 9 out |
| » Lost to Pirates (37-43), 7-6 | Polo Grounds V (25-17) | 39-40 | Lost 2 |
| » Starters: Tiny Bonham vs Hank Behrman | Fifth | 9 out |
| Sunday, July 17 |
| » Lost to Cardinals (49-34), 10-1 | Polo Grounds V (25-18) | 39-41 | Lost 3 |
| » Starters: Red Munger vs Dave Koslo | Fifth | 10 out |
| Monday, July 18 |
| » Defeated Cardinals (49-35), 7-4 | Polo Grounds V (26-18) | 40-41 | |
| » Starters: Al Brazle vs Monte Kennedy | Fifth | 10 out |
| Tuesday, July 19 |
| » Defeated Reds (34-49), 13-3 | Polo Grounds V (27-18) | 41-41 | Won 2 |
| » Starters: Howie Fox vs Larry Jansen | Fifth | 10 out |
| Wednesday, July 20 |
| » Defeated Reds (34-50), 5-1 | Polo Grounds V (28-18) | 42-41 | Won 3 |
| » Starters: Ken Raffensberger vs Dave Koslo | Fifth | 9 out |
| Thursday, July 21 |
| » Defeated Reds (34-51), 9-5 | Polo Grounds V (29-18) | 43-41 | Won 4 |
| » Starters: Herm Wehmeier vs Clint Hartung | Fifth | 9 out |
| Friday, July 22 |
| » Lost to Cubs (33-56), 6-5 | Polo Grounds V (29-19) | 43-42 | |
| » Starters: Johnny Schmitz vs Monte Kennedy | Fifth | 9 out |
| Saturday, July 23 |
| » Defeated Cubs (33-57), 10-6 | Polo Grounds V (30-19) | 44-42 | |
| » Starters: Warren Hacker vs Sheldon Jones | Fifth | 8 out |
| Sunday, July 24 |
| » Lost to Cubs (34-57), 5-3 | Polo Grounds V (30-20) | 44-43 | |
| » Starters: Bob Rush vs Dave Koslo | Fifth | 9 out |
| » Lost to Cubs (35-57), 6-1 | Polo Grounds V (30-21) | 44-44 | Lost 2 |
| » Starters: Doyle Lade vs Larry Jansen | Fifth | 9 out |
| Tuesday, July 26 |
| » Lost to Pirates (44-46), 4-1 | Forbes Field (1-5) | 44-45 | Lost 3 |
| » Starters: Andy Hansen vs Tiny Bonham | Fifth | 10 out |
| Wednesday, July 27 |
| » Defeated Pirates (44-47), 8-3 | Forbes Field (2-5) | 45-45 | |
| » Starters: Clint Hartung vs Bob Chesnes | Fifth | 10 out |
| Thursday, July 28 |
| » Defeated Pirates (44-48), 8-6 | Forbes Field (3-5) | 46-45 | Won 2 |
| » Starters: Larry Jansen vs Murry Dickson | Fourth | 10 out |
| Future Giant Vida Blue is born in Mansfield, LA. |
| Friday, July 29 |
| » Lost to Reds (38-55), 3-0 | Crosley Field (3-1) | 46-46 | |
| » Starters: Dave Koslo vs Herm Wehmeier | Fourth | 10½ out |
| Saturday, July 30 |
| » Defeated Reds (38-56), 8-7 | Crosley Field (4-1) | 47-46 | |
| » Starters: Monte Kennedy vs Howie Fox | Fifth | 10½ out |
| Sunday, July 31 |
| » Defeated Reds (38-57), 10-0 | Crosley Field (5-1) | 48-46 | Won 2 |
| » Starters: Larry Jansen vs Kent Peterson | Fourth | 9 out |
| » Defeated Reds (38-58), 9-0 | Crosley Field (6-1) | 49-46 | Won 3 |
| » Starters: Adrian Zabala vs Ken Raffensberger | Fourth | 9 out |
| Monday, August 1 |
| » Defeated Cubs (36-63), 11-3 | Wrigley Field (2-4) | 50-46 | Won 4 |
| » Starters: Clint Hartung vs Bob Chipman | Fourth | 8 out |
| Tuesday, August 2 |
| » Defeated Cubs (36-64), 3-0 | Wrigley Field (3-4) | 51-46 | Won 5 |
| » Starters: Sheldon Jones vs Dutch Leonard | Third | 8 out |
| Wednesday, August 3 |
| » Defeated Cubs (36-65), 4-1 | Wrigley Field (4-4) | 52-46 | Won 6 |
| » Starters: Dave Koslo vs Bob Rush | Third | 8 out |
| Thursday, August 4 |
| » Lost to Cubs (37-65), 1-0 | Wrigley Field (4-5) | 52-47 | |
| » Starters: Larry Jansen vs Johnny Schmitz | Third | 9 out |
| Friday, August 5 |
| » Lost to Cardinals (62-38), 1-0 | Sportsman's Park III (2-5) | 52-48 | Lost 2 |
| » Starters: Monte Kennedy vs Gerry Staley | Third | 10 out |
| Saturday, August 6 |
| » Defeated Cardinals (62-39), 3-1 | Sportsman's Park III (3-5) | 53-48 | |
| » Starters: Adrian Zabala vs Max Lanier | Third | 9 out |
| Sunday, August 7 |
| » Lost to Cardinals (63-39), 9-2 | Sportsman's Park III (3-6) | 53-49 | |
| » Starters: Clint Hartung vs Red Munger | Second | 10 out |
| Monday, August 8 |
| » Lost to Dodgers (64-39), 2-1 | Ebbets Field (2-5) | 53-50 | Lost 2 |
| » Starters: Dave Koslo vs Don Newcombe | Second | 11 out |
| Tuesday, August 9 |
| » Defeated Braves (53-53), 4-3 | Polo Grounds V (31-21) | 54-50 | |
| » Starters: Johnny Sain vs Larry Jansen | Second | 11 out |
| Wednesday, August 10 |
| » Lost to Braves (54-53), 4-1 | Polo Grounds V (31-22) | 54-51 | |
| » Starters: Warren Spahn vs Monte Kennedy | Second | 12 out |
| Thursday, August 11 |
| » Tied Braves, 7-7 | Polo Grounds V (31-22) | 54-51 | |
| » Starters: Vern Bickford vs Adrian Zabala | Third | 12½ out |
| Friday, August 12 |
| » Lost to Phillies (54-55), 2-0 | Polo Grounds V (31-23) | 54-52 | Lost 2 |
| » Starters: Hank Borowy vs Sheldon Jones | Fourth | 13 out |
| Sunday, August 14 |
| » Defeated Phillies (54-56), 8-1 | Polo Grounds V (32-23) | 55-52 | |
| » Starters: Robin Roberts vs Dave Koslo | Third | 12 out |
| » Defeated Phillies (54-57), 1-0 | Polo Grounds V (33-23) | 56-52 | Won 2 |
| » Starters: Russ Meyer vs Larry Jansen | Third | 12 out |
| Tuesday, August 16 |
| » Defeated Braves (55-55), 4-0 | Braves Field (3-4) | 57-52 | Won 3 |
| » Starters: Monte Kennedy vs Warren Spahn | Third | 11 out |
| Wednesday, August 17 |
| » Lost to Braves (56-55), 13-4 | Braves Field (3-5) | 57-53 | |
| » Starters: Clint Hartung vs Vern Bickford | Third | 11½ out |
| Thursday, August 18 |
| » Lost to Braves (57-55), 10-6 | Braves Field (3-6) | 57-54 | Lost 2 |
| » Starters: Larry Jansen vs Johnny Sain | Third | 12 out |
| Friday, August 19 |
| » Lost to Phillies (58-57), 7-1 | Shibe Park (3-4) | 57-55 | Lost 3 |
| » Starters: Dave Koslo vs Robin Roberts | Second | 12 out |
| Saturday, August 20 |
| » Lost to Phillies (59-57), 9-3 | Shibe Park (3-5) | 57-56 | Lost 4 |
| » Starters: Monte Kennedy vs Russ Meyer | Fifth | 13 out |
| Sunday, August 21 |
| » Lost to Phillies (60-57), 4-0 | Shibe Park (3-6) | 57-57 | Lost 5 |
| » Starters: Sheldon Jones vs Ken Heintzelman | Fifth | 13 out |
| » Defeated Phillies (60-58), 4-2 | Shibe Park (4-6) | 58-57 | |
| » Starters: Larry Jansen vs Schoolboy Rowe | Fifth | 13 out |
| Tuesday, August 23 |
| » Lost to Cubs (46-74), 7-5 | Polo Grounds V (33-24) | 58-58 | |
| » Starters: Doyle Lade vs Dave Koslo | Fifth | 13½ out |
| Wednesday, August 24 |
| » Defeated Cubs (46-75), 5-3 | Polo Grounds V (34-24) | 59-58 | |
| » Starters: Dewey Adkins vs Sheldon Jones | Fifth | 12½ out |
| Thursday, August 25 |
| » Lost to Cardinals (73-46), 5-2 | Polo Grounds V (34-25) | 59-59 | |
| » Starters: Red Munger vs Monte Kennedy | Fifth | 13½ out |
| Former Giant Mule Watson dies in Shreveport, LA at the age of 53. |
| Friday, August 26 |
| » Defeated Cardinals (73-47), 4-2 | Polo Grounds V (35-25) | 60-59 | |
| » Starters: Gerry Staley vs Larry Jansen | Fifth | 12½ out |
| Saturday, August 27 |
| » Lost to Cardinals (74-47), 5-2 | Polo Grounds V (35-26) | 60-60 | |
| » Starters: Fred Martin vs Dave Koslo | Fifth | 14½ out |
| » Lost to Cardinals (75-47), 11-2 | Polo Grounds V (35-27) | 60-61 | Lost 2 |
| » Starters: Harry Brecheen vs Sheldon Jones | Fifth | 14½ out |
| Sunday, August 28 |
| » Lost to Reds (50-72), 10-3 | Polo Grounds V (35-28) | 60-62 | Lost 3 |
| » Starters: Herm Wehmeier vs Adrian Zabala | Fifth | 15½ out |
| » Defeated Reds (50-73), 4-2 | Polo Grounds V (36-28) | 61-62 | |
| » Starters: Buddy Lively vs Monte Kennedy | Fifth | 15½ out |
| Monday, August 29 |
| » Defeated Reds (50-74), 3-2 | Polo Grounds V (37-28) | 62-62 | Won 2 |
| » Starters: Ken Raffensberger vs Larry Jansen | Fifth | 15½ out |
| Wednesday, August 31 |
| » Defeated Pirates (57-68), 12-5 | Polo Grounds V (38-28) | 63-62 | Won 3 |
| » Starters: Bill Werle vs Sheldon Jones | Fifth | 14½ out |
| Thursday, September 1 |
| » Defeated Pirates (57-69), 9-5 | Polo Grounds V (39-28) | 64-62 | Won 4 |
| » Starters: Junior Walsh vs Hank Behrman | Fourth | 14½ out |
| Future Giant Garry Maddox is born in Cincinnati, OH. |
| Friday, September 2 |
| » Lost to Dodgers (78-50), 8-0 | Polo Grounds V (39-29) | 64-63 | |
| » Starters: Don Newcombe vs Dave Koslo | Fifth | 15 out |
| Saturday, September 3 |
| » Defeated Dodgers (78-51), 6-3 | Polo Grounds V (40-29) | 65-63 | |
| » Starters: Jack Banta vs Monte Kennedy | Fifth | 14½ out |
| Sunday, September 4 |
| » Lost to Dodgers (79-51), 6-2 | Polo Grounds V (40-30) | 65-64 | |
| » Starters: Rex Barney vs Larry Jansen | Fifth | 16 out |
| Monday, September 5 |
| » Lost to Phillies (69-63), 9-7 | Polo Grounds V (40-31) | 65-65 | Lost 2 |
| » Starters: Ken Heintzelman vs Clint Hartung | Fifth | 17 out |
| » Lost to Phillies (70-63), 4-2 | Polo Grounds V (40-32) | 65-66 | Lost 3 |
| » Starters: Russ Meyer vs Dave Koslo | Fifth | 17 out |
| Tuesday, September 6 |
| » Lost to Phillies (71-63), 4-2 | Polo Grounds V (40-33) | 65-67 | Lost 4 |
| » Starters: Robin Roberts vs Larry Jansen | Fifth | 17 out |
| » Defeated Phillies (71-64), 4-1 | Polo Grounds V (41-33) | 66-67 | |
| » Starters: Hank Borowy vs Sheldon Jones | Fifth | 17 out |
| Thursday, September 8 |
| » Lost to Dodgers (84-51), 12-7 | Ebbets Field (2-6) | 66-68 | |
| » Starters: Monte Kennedy vs Rex Barney | Fourth | 18½ out |
| Friday, September 9 |
| » Defeated Dodgers (84-52), 10-1 | Ebbets Field (3-6) | 67-68 | |
| » Starters: Dave Koslo vs Preacher Roe | Fourth | 17½ out |
| Saturday, September 10 |
| » Lost to Dodgers (85-52), 5-4 | Ebbets Field (3-7) | 67-69 | |
| » Starters: Monte Kennedy vs Don Newcombe | Fifth | 18½ out |
| Sunday, September 11 |
| » Lost to Dodgers (86-52), 10-5 | Ebbets Field (3-8) | 67-70 | Lost 2 |
| » Starters: Sheldon Jones vs Jack Banta | Fourth | 20 out |
| Tuesday, September 13 |
| » Lost to Cardinals (88-50), 1-0 | Sportsman's Park III (3-7) | 67-71 | Lost 3 |
| » Starters: Dave Koslo vs Red Munger | Fifth | 21 out |
| Wednesday, September 14 |
| » Lost to Cardinals (89-50), 9-3 | Sportsman's Park III (3-8) | 67-72 | Lost 4 |
| » Starters: Monte Kennedy vs Harry Brecheen | Fifth | 22 out |
| Thursday, September 15 |
| Future Giant Don Carrithers is born in Lynwood, CA. |
| Friday, September 16 |
| » Lost to Cubs (56-85), 5-4 | Wrigley Field (4-6) | 67-73 | Lost 5 |
| » Starters: Larry Jansen vs Doyle Lade | Fifth | 23 out |
| » Major-league debuts: Davey Williams (Giants) |
| Saturday, September 17 |
| » Lost to Cubs (57-85), 4-2 | Wrigley Field (4-7) | 67-74 | Lost 6 |
| » Starters: Dave Koslo vs Dutch Leonard | Fifth | 23 out |
| Sunday, September 18 |
| » Defeated Pirates (62-79), 13-4 | Forbes Field (4-5) | 68-74 | |
| » Starters: Sheldon Jones vs Bob Chesnes | Fifth | 23½ out |
| » Lost to Pirates (63-79), 7-2 | Forbes Field (4-6) | 68-75 | |
| » Starters: Monte Kennedy vs Cliff Chambers | Fifth | 23½ out |
| Monday, September 19 |
| » Defeated Pirates (63-80), 6-4 | Forbes Field (5-6) | 69-75 | |
| » Starters: Kirby Higbe vs Junior Walsh | Fifth | 22½ out |
| Wednesday, September 21 |
| » Lost to Reds (59-85), 5-4 | Crosley Field (6-2) | 69-76 | |
| » Starters: Larry Jansen vs Herm Wehmeier | Fifth | 23 out |
| » Defeated Reds (59-86), 5-2 | Crosley Field (7-2) | 70-76 | |
| » Starters: Dave Koslo vs Howie Fox | Fifth | 23 out |
| Thursday, September 22 |
| » Defeated Reds (59-87), 3-1 | Crosley Field (8-2) | 71-76 | Won 2 |
| » Starters: Monte Kennedy vs Johnny Vander Meer | Fifth | 22½ out |
| » Lost to Reds (60-87), 8-4 | Crosley Field (8-3) | 71-77 | |
| » Starters: Roger Bowman vs Harry Perkowski | Fifth | 22½ out |
| » Major-league debuts: Roger Bowman (Giants) |
| Friday, September 23 |
| » Major-league debuts: Wally Hood (Yankees) |
| Saturday, September 24 |
| » Lost to Braves (73-75), 6-4 | Polo Grounds V (41-34) | 71-78 | Lost 2 |
| » Starters: Warren Spahn vs Larry Jansen | Fifth | 23½ out |
| Sunday, September 25 |
| » Defeated Braves (73-76), 3-2 | Polo Grounds V (42-34) | 72-78 | |
| » Starters: Vern Bickford vs Dave Koslo | Fifth | 23 out |
| » Defeated Braves (73-77), 5-2 | Polo Grounds V (43-34) | 73-78 | Won 2 |
| » Starters: Bill Voiselle vs Roger Bowman | Fifth | 23 out |
| Wednesday, September 28 |
| » Lost to Phillies (80-72), 2-0 | Shibe Park (4-7) | 73-79 | |
| » Starters: Sheldon Jones vs Russ Meyer | Fifth | 23 out |
| Saturday, October 1 |
| » Lost to Braves (74-79), 3-0 | Braves Field (3-7) | 73-80 | Lost 2 |
| » Starters: Dave Koslo vs Vern Bickford | Fifth | 23 out |
| Sunday, October 2 |
| » Lost to Braves (75-79), 2-1 | Braves Field (3-8) | 73-81 | Lost 3 |
| » Starters: Monte Kennedy vs Warren Spahn | Fifth | 24 out |
| Saturday, October 8 |
| Future Giant Enos Cabell is born in Fort Riley, KS. |
| Thursday, October 20 |
| Former Giant Dick Rudolph dies in Bronx, NY at the age of 63. |
Game information provided by Retrosheet (www.retrosheet.org) |