| Monday, January 5 |
| Future Tiger Bill Laxton is born in Camden, NJ. |
| Tuesday, January 13 |
| Future Tiger Les Cain is born in San Luis Obispo, CA. |
| Friday, January 23 |
| Former Tiger Frank Doljack dies in Cleveland, OH at the age of 41. |
| Saturday, February 21 |
| Future Tiger Bill Slayback is born in Hollywood, CA. |
| Saturday, March 20 |
| Future Tiger Chuck Seelbach is born in Lakewood, OH. |
| Monday, April 19 |
| » Major-league debuts: Monty Basgall and Ed Fitz Gerald (Pirates) |
| Tuesday, April 20 |
| » Defeated White Sox (0-1), 5-2 | Comiskey Park I (1-0) | 1-0 | |
| » Starters: Hal Newhouser vs Joe Haynes | Second | ½ out |
| » Major-league debuts: Neil Berry and George Vico (Tigers) |
| Wednesday, April 21 |
| » Defeated White Sox (0-2), 4-3 | Comiskey Park I (2-0) | 2-0 | Won 2 |
| » Starters: Dizzy Trout vs Orval Grove | First | -- |
| » Major-league debuts: Jim Delsing (White Sox) |
| Thursday, April 22 |
| » Defeated White Sox (0-3), 3-2 | Comiskey Park I (3-0) | 3-0 | Won 3 |
| » Starters: Virgil Trucks vs Howie Judson | First | -- |
| » Major-league debuts: Howie Judson (White Sox) |
| Friday, April 23 |
| » Lost to Indians (2-0), 8-2 | Tiger Stadium (0-1) | 3-1 | |
| » Starters: Bob Lemon vs Fred Hutchinson | Second | 1 out |
| Saturday, April 24 |
| » Lost to Indians (3-0), 4-1 | Tiger Stadium (0-2) | 3-2 | Lost 2 |
| » Starters: Bob Feller vs Art Houtteman | Third | 1 out |
| Sunday, April 25 |
| » Lost to Indians (4-0), 7-4 | Tiger Stadium (0-3) | 3-3 | Lost 3 |
| » Starters: Al Gettel vs Hal Newhouser | Fifth | 2 out |
| » Major-league debuts: Ray Murray (Indians) |
| Monday, April 26 |
| » Lost to Browns (3-2), 2-1 | Sportsman's Park III (0-1) | 3-4 | Lost 4 |
| » Starters: Dizzy Trout vs Fred Sanford | Sixth | 3 out |
| Tuesday, April 27 |
| » Lost to Browns (4-2), 9-8 | Sportsman's Park III (0-2) | 3-5 | Lost 5 |
| » Starters: Fred Hutchinson vs Bryan Stephens | Sixth | 3½ out |
| Wednesday, April 28 |
| » Defeated Browns (4-3), 9-4 | Sportsman's Park III (1-2) | 4-5 | |
| » Starters: Virgil Trucks vs Al Gerheauser | Fifth | 3 out |
| » Major-league debuts: Ned Garver and Ken Wood (Browns) |
| Thursday, April 29 |
| » Lost to White Sox (2-6), 5-4 | Tiger Stadium (0-4) | 4-6 | |
| » Starters: Joe Haynes vs Art Houtteman | Sixth | 4 out |
| Friday, April 30 |
| » Lost to White Sox (3-6), 5-4 | Tiger Stadium (0-5) | 4-7 | Lost 2 |
| » Starters: Bill Wight vs Hal Newhouser | Fifth | 4½ out |
| Saturday, May 1 |
| » Defeated Indians (6-1), 10-3 | Cleveland Stadium (1-0) | 5-7 | |
| » Starters: Dizzy Trout vs Bob Feller | Sixth | 3½ out |
| Sunday, May 2 |
| » Defeated Indians (6-2), 4-2 | Cleveland Stadium (2-0) | 6-7 | Won 2 |
| » Starters: Fred Hutchinson vs Bob Lemon | Fifth | 2½ out |
| » Major-league debuts: Joe Tipton (Indians) |
| Tuesday, May 4 |
| » Lost to Red Sox (6-6), 6-3 | Fenway Park (0-1) | 6-8 | |
| » Starters: Art Houtteman vs Dave Ferriss | Sixth | 2½ out |
| Wednesday, May 5 |
| » Lost to Red Sox (7-6), 4-3 | Fenway Park (0-2) | 6-9 | Lost 2 |
| » Starters: Virgil Trucks vs Mel Parnell | Seventh | 3 out |
| Thursday, May 6 |
| » Defeated Red Sox (7-7), 8-3 | Fenway Park (1-2) | 7-9 | |
| » Starters: Hal Newhouser vs Jack Kramer | Sixth | 3 out |
| Saturday, May 8 |
| » Defeated Yankees (8-6), 3-2 | Yankee Stadium (1-0) | 8-9 | Won 2 |
| » Starters: Fred Hutchinson vs Ed Lopat | Sixth | 3½ out |
| » Lost to Yankees (9-6), 9-1 | Yankee Stadium (1-1) | 8-10 | |
| » Starters: Hal Newhouser vs Vic Raschi | Sixth | 3½ out |
| Sunday, May 9 |
| » Lost to Athletics (11-5), 10-5 | Shibe Park (0-1) | 8-11 | Lost 2 |
| » Starters: Dizzy Trout vs Joe Coleman | Seventh | 5 out |
| » Lost to Athletics (12-5), 5-3 | Shibe Park (0-2) | 8-12 | Lost 3 |
| » Starters: Art Houtteman vs Lou Brissie | Seventh | 5 out |
| Tuesday, May 11 |
| » Defeated Senators (9-10), 4-1 | Griffith Stadium (1-0) | 9-12 | |
| » Starters: Virgil Trucks vs Mickey Haefner | Fifth | 5½ out |
| Wednesday, May 12 |
| » Defeated Senators (9-11), 14-9 | Griffith Stadium (2-0) | 10-12 | Won 2 |
| » Starters: Hal Newhouser vs Sid Hudson | Fourth | 5½ out |
| Friday, May 14 |
| » Lost to Browns (7-10), 3-0 | Tiger Stadium (0-6) | 10-13 | |
| » Starters: Fred Sanford vs Fred Hutchinson | Fifth | 5½ out |
| Saturday, May 15 |
| » Defeated Browns (7-11), 4-1 | Tiger Stadium (1-6) | 11-13 | |
| » Starters: Ned Garver vs Dizzy Trout | Fifth | 6 out |
| Sunday, May 16 |
| » Lost to Browns (8-11), 3-2 | Tiger Stadium (1-7) | 11-14 | |
| » Starters: Sam Zoldak vs Art Houtteman | Fifth | 6½ out |
| Tuesday, May 18 |
| » Defeated Red Sox (11-12), 10-7 | Tiger Stadium (2-7) | 12-14 | |
| » Starters: Dave Ferriss vs Virgil Trucks | Fifth | 5 out |
| Wednesday, May 19 |
| » Defeated Red Sox (11-13), 4-1 | Tiger Stadium (3-7) | 13-14 | Won 2 |
| » Starters: Ellis Kinder vs Hal Newhouser | Fourth | 5 out |
| Thursday, May 20 |
| » Defeated Athletics (16-9), 4-2 | Tiger Stadium (4-7) | 14-14 | Won 3 |
| » Starters: Carl Scheib vs Fred Hutchinson | Fourth | 5 out |
| Friday, May 21 |
| » Lost to Athletics (17-9), 9-6 | Tiger Stadium (4-8) | 14-15 | |
| » Starters: Joe Coleman vs Dizzy Trout | Fourth | 5 out |
| Saturday, May 22 |
| » Defeated Athletics (17-10), 6-5 | Tiger Stadium (5-8) | 15-15 | |
| » Starters: Phil Marchildon vs Art Houtteman | Fifth | 5 out |
| Sunday, May 23 |
| » Lost to Senators (12-16), 1-0 | Tiger Stadium (5-9) | 15-16 | |
| » Starters: Walt Masterson vs Virgil Trucks | Fourth | 5½ out |
| Monday, May 24 |
| » Defeated Senators (12-17), 5-2 | Tiger Stadium (6-9) | 16-16 | |
| » Starters: Early Wynn vs Hal Newhouser | Fourth | 5 out |
| Tuesday, May 25 |
| » Lost to Yankees (18-11), 16-5 | Tiger Stadium (6-10) | 16-17 | |
| » Starters: Vic Raschi vs Fred Hutchinson | Fourth | 6 out |
| Wednesday, May 26 |
| » Defeated Yankees (18-12), 7-3 | Tiger Stadium (7-10) | 17-17 | |
| » Starters: Spec Shea vs Dizzy Trout | Fourth | 5 out |
| Friday, May 28 |
| » Lost to Browns (14-15), 5-4 | Sportsman's Park III (1-3) | 17-18 | |
| » Starters: Art Houtteman vs Fred Sanford | Fourth | 7 out |
| Saturday, May 29 |
| » Lost to Browns (15-15), 6-1 | Sportsman's Park III (1-4) | 17-19 | Lost 2 |
| » Starters: Virgil Trucks vs Sam Zoldak | Fifth | 8 out |
| Sunday, May 30 |
| » Defeated Browns (15-16), 6-4 | Sportsman's Park III (2-4) | 18-19 | |
| » Starters: Hal Newhouser vs Ned Garver | Fourth | 7½ out |
| Monday, May 31 |
| » Defeated White Sox (8-26), 5-4 | Tiger Stadium (8-10) | 19-19 | Won 2 |
| » Starters: Orval Grove vs Dizzy Trout | Fourth | 7½ out |
| » Lost to White Sox (9-26), 9-3 | Tiger Stadium (8-11) | 19-20 | |
| » Starters: Ike Pearson vs Art Houtteman | Fourth | 7½ out |
| Wednesday, June 2 |
| » Lost to Yankees (22-16), 1-0 | Yankee Stadium (1-2) | 19-21 | Lost 2 |
| » Starters: Art Houtteman vs Vic Raschi | Fifth | 6½ out |
| Thursday, June 3 |
| » Defeated Yankees (22-17), 6-2 | Yankee Stadium (2-2) | 20-21 | |
| » Starters: Hal Newhouser vs Ed Lopat | Fourth | 6 out |
| Friday, June 4 |
| » Lost to Yankees (23-17), 7-4 | Yankee Stadium (2-3) | 20-22 | |
| » Starters: Dizzy Trout vs Frank Hiller | Fourth | 7 out |
| Sunday, June 6 |
| » Lost to Red Sox (19-24), 5-4 | Fenway Park (1-3) | 20-23 | Lost 2 |
| » Starters: Virgil Trucks vs Mickey Harris | Fourth | 9½ out |
| » Lost to Red Sox (20-24), 12-4 | Fenway Park (1-4) | 20-24 | Lost 3 |
| » Starters: Art Houtteman vs Ellis Kinder | Fourth | 9½ out |
| Tuesday, June 8 |
| » Defeated Athletics (27-18), 2-1 | Shibe Park (1-2) | 21-24 | |
| » Starters: Hal Newhouser vs Lou Brissie | Fourth | 9½ out |
| Wednesday, June 9 |
| » Defeated Athletics (27-19), 7-4 | Shibe Park (2-2) | 22-24 | Won 2 |
| » Starters: Dizzy Trout vs Carl Scheib | Fifth | 9 out |
| Thursday, June 10 |
| » Lost to Athletics (28-19), 10-4 | Shibe Park (2-3) | 22-25 | |
| » Starters: Virgil Trucks vs Joe Coleman | Fifth | 9 out |
| Friday, June 11 |
| » Defeated Senators (24-25), 7-6 | Griffith Stadium (3-0) | 23-25 | |
| » Starters: Stubby Overmire vs Walt Masterson | Fifth | 9 out |
| Saturday, June 12 |
| » Defeated Senators (24-26), 4-1 | Griffith Stadium (4-0) | 24-25 | Won 2 |
| » Starters: Hal Newhouser vs Ray Scarborough | Fourth | 9½ out |
| Sunday, June 13 |
| » Defeated Senators (24-27), 9-3 | Griffith Stadium (5-0) | 25-25 | Won 3 |
| » Starters: Dizzy Trout vs Sid Hudson | Fourth | 8 out |
| » Defeated Senators (24-28), 9-2 | Griffith Stadium (6-0) | 26-25 | Won 4 |
| » Starters: Virgil Trucks vs Early Wynn | Fourth | 8 out |
| Tuesday, June 15 |
| » Defeated Athletics (31-21), 4-1 | Tiger Stadium (9-11) | 27-25 | Won 5 |
| » Starters: Joe Coleman vs Hal Newhouser | Fourth | 7 out |
| Wednesday, June 16 |
| » Defeated Athletics (31-22), 2-1 | Tiger Stadium (10-11) | 28-25 | Won 6 |
| » Starters: Lou Brissie vs Art Houtteman | Fourth | 6 out |
| Future Tiger Ron LeFlore is born in Detroit, MI. |
| Thursday, June 17 |
| » Lost to Athletics (32-22), 5-2 | Tiger Stadium (10-12) | 28-26 | |
| » Starters: Carl Scheib vs Dizzy Trout | Fourth | 6 out |
| Saturday, June 19 |
| » Lost to Red Sox (26-26), 9-7 | Tiger Stadium (10-13) | 28-27 | Lost 2 |
| » Starters: Jack Kramer vs Virgil Trucks | Fourth | 6½ out |
| Sunday, June 20 |
| » Lost to Red Sox (27-26), 8-3 | Tiger Stadium (10-14) | 28-28 | Lost 3 |
| » Starters: Mel Parnell vs Hal Newhouser | Fifth | 8 out |
| Tuesday, June 22 |
| » Lost to Senators (26-32), 5-4 | Tiger Stadium (10-15) | 28-29 | Lost 4 |
| » Starters: Mickey Haefner vs Art Houtteman | Fifth | 8½ out |
| Wednesday, June 23 |
| » Lost to Senators (27-32), 2-1 | Tiger Stadium (10-16) | 28-30 | Lost 5 |
| » Starters: Walt Masterson vs Dizzy Trout | Fifth | 8½ out |
| Friday, June 25 |
| » Defeated Yankees (35-25), 4-2 | Tiger Stadium (11-16) | 29-30 | |
| » Starters: Red Embree vs Hal Newhouser | Fifth | 7 out |
| Saturday, June 26 |
| » Lost to Yankees (36-25), 8-5 | Tiger Stadium (11-17) | 29-31 | |
| » Starters: Allie Reynolds vs Virgil Trucks | Fifth | 8 out |
| Sunday, June 27 |
| » Lost to Yankees (37-25), 7-0 | Tiger Stadium (11-18) | 29-32 | Lost 2 |
| » Starters: Tommy Byrne vs Dizzy Trout | Fifth | 8½ out |
| Tuesday, June 29 |
| » Lost to Indians (38-23), 6-2 | Tiger Stadium (11-19) | 29-33 | Lost 3 |
| » Starters: Bob Feller vs Hal Newhouser | Sixth | 9½ out |
| Wednesday, June 30 |
| » Lost to Indians (39-23), 2-0 | Tiger Stadium (11-20) | 29-34 | Lost 4 |
| » Starters: Bob Lemon vs Art Houtteman | Sixth | 10½ out |
| Thursday, July 1 |
| » Defeated Indians (39-24), 9-5 | Tiger Stadium (12-20) | 30-34 | |
| » Starters: Bob Muncrief vs Fred Hutchinson | Fifth | 9½ out |
| Friday, July 2 |
| » Lost to White Sox (20-41), 5-2 | Comiskey Park I (3-1) | 30-35 | |
| » Starters: Dizzy Trout vs Marino Pieretti | Sixth | 10½ out |
| Saturday, July 3 |
| » Defeated White Sox (20-42), 6-2 | Comiskey Park I (4-1) | 31-35 | |
| » Starters: Hal Newhouser vs Joe Haynes | Fifth | 10½ out |
| Sunday, July 4 |
| » Defeated White Sox (20-43), 6-3 | Comiskey Park I (5-1) | 32-35 | Won 2 |
| » Starters: Virgil Trucks vs Bill Wight | Fifth | 10½ out |
| » Lost to White Sox (21-43), 12-1 | Comiskey Park I (5-2) | 32-36 | |
| » Starters: Stubby Overmire vs Al Gettel | Fifth | 10½ out |
| Monday, July 5 |
| » Lost to Indians (42-24), 6-3 | Cleveland Stadium (2-1) | 32-37 | Lost 2 |
| » Starters: Art Houtteman vs Bob Lemon | Fifth | 10½ out |
| » Defeated Indians (42-25), 7-5 | Cleveland Stadium (3-1) | 33-37 | |
| » Starters: Fred Hutchinson vs Sam Zoldak | Fifth | 10½ out |
| Tuesday, July 6 |
| » Defeated Indians (42-26), 9-0 | Cleveland Stadium (4-1) | 34-37 | Won 2 |
| » Starters: Dizzy Trout vs Bob Muncrief | Fifth | 9½ out |
| Wednesday, July 7 |
| » Defeated Browns (26-43), 6-0 | Tiger Stadium (13-20) | 35-37 | Won 3 |
| » Starters: Bill Kennedy vs Hal Newhouser | Fifth | 9½ out |
| Thursday, July 8 |
| » Defeated Browns (26-44), 12-2 | Tiger Stadium (14-20) | 36-37 | Won 4 |
| » Starters: Frank Biscan vs Virgil Trucks | Fifth | 9½ out |
| Future Tiger Lerrin LaGrow is born in Phoenix, AZ. |
| Friday, July 9 |
| » Defeated White Sox (23-47), 4-2 | Tiger Stadium (15-20) | 37-37 | Won 5 |
| » Starters: Marino Pieretti vs Fred Hutchinson | Fifth | 8½ out |
| Saturday, July 10 |
| » Defeated White Sox (23-48), 5-4 | Tiger Stadium (16-20) | 38-37 | Won 6 |
| » Starters: Joe Haynes vs Dizzy Trout | Fifth | 8 out |
| Sunday, July 11 |
| » Defeated White Sox (23-49), 5-4 | Tiger Stadium (17-20) | 39-37 | Won 7 |
| » Starters: Bill Wight vs Hal Newhouser | Fifth | 7½ out |
| Thursday, July 15 |
| » Lost to Red Sox (40-35), 13-5 | Fenway Park (1-5) | 39-38 | |
| » Starters: Fred Hutchinson vs Jack Kramer | Fifth | 9½ out |
| » Lost to Red Sox (41-35), 3-1 | Fenway Park (1-6) | 39-39 | Lost 2 |
| » Starters: Dizzy Trout vs Mel Parnell | Fifth | 9½ out |
| Friday, July 16 |
| » Lost to Red Sox (42-35), 5-3 | Fenway Park (1-7) | 39-40 | Lost 3 |
| » Starters: Art Houtteman vs Joe Dobson | Fifth | 9½ out |
| Saturday, July 17 |
| » Defeated Red Sox (42-36), 3-1 | Fenway Park (2-7) | 40-40 | |
| » Starters: Virgil Trucks vs Ellis Kinder | Fifth | 8½ out |
| Sunday, July 18 |
| » Defeated Yankees (46-34), 5-3 | Yankee Stadium (3-3) | 41-40 | Won 2 |
| » Starters: Hal Newhouser vs Vic Raschi | Fifth | 9½ out |
| » Lost to Yankees (47-34), 12-4 | Yankee Stadium (3-4) | 41-41 | |
| » Starters: Fred Hutchinson vs Tommy Byrne | Fifth | 9½ out |
| Tuesday, July 20 |
| » Defeated Yankees (47-35), 2-1 | Yankee Stadium (4-4) | 42-41 | |
| » Starters: Virgil Trucks vs Allie Reynolds | Fifth | 9 out |
| Wednesday, July 21 |
| » Lost to Senators (37-47), 6-1 | Griffith Stadium (6-1) | 42-42 | |
| » Starters: Fred Hutchinson vs Walt Masterson | Fourth | 9½ out |
| Thursday, July 22 |
| » Lost to Senators (38-47), 9-8 | Griffith Stadium (6-2) | 42-43 | Lost 2 |
| » Starters: Hal Newhouser vs Early Wynn | Fifth | 9½ out |
| Friday, July 23 |
| » Defeated Senators (38-48), 11-5 | Griffith Stadium (7-2) | 43-43 | |
| » Starters: Stubby Overmire vs Mickey Haefner | Fifth | 9 out |
| Saturday, July 24 |
| » Lost to Athletics (55-37), 8-6 | Shibe Park (2-4) | 43-44 | |
| » Starters: Art Houtteman vs Phil Marchildon | Fifth | 9½ out |
| Sunday, July 25 |
| » Lost to Athletics (56-37), 4-0 | Shibe Park (2-5) | 43-45 | Lost 2 |
| » Starters: Virgil Trucks vs Joe Coleman | Fifth | 9½ out |
| » Defeated Athletics (56-38), 10-2 | Shibe Park (3-5) | 44-45 | |
| » Starters: Fred Hutchinson vs Carl Scheib | Fifth | 9½ out |
| Monday, July 26 |
| Future Tiger John Knox is born in Newark, NJ. |
| Tuesday, July 27 |
| » Lost to Red Sox (55-36), 8-0 | Tiger Stadium (17-21) | 44-46 | |
| » Starters: Ellis Kinder vs Hal Newhouser | Fifth | 10½ out |
| Wednesday, July 28 |
| » Defeated Red Sox (55-37), 13-0 | Tiger Stadium (18-21) | 45-46 | |
| » Starters: Denny Galehouse vs Dizzy Trout | Fifth | 9½ out |
| Thursday, July 29 |
| » Lost to Red Sox (56-37), 8-1 | Tiger Stadium (18-22) | 45-47 | |
| » Starters: Jack Kramer vs Virgil Trucks | Fifth | 10½ out |
| Friday, July 30 |
| » Defeated Athletics (57-40), 17-2 | Tiger Stadium (19-22) | 46-47 | |
| » Starters: Joe Coleman vs Fred Hutchinson | Fifth | 10½ out |
| Saturday, July 31 |
| » Lost to Athletics (58-40), 8-3 | Tiger Stadium (19-23) | 46-48 | |
| » Starters: Bill McCahan vs Art Houtteman | Fifth | 10½ out |
| Sunday, August 1 |
| » Lost to Athletics (59-40), 4-2 | Tiger Stadium (19-24) | 46-49 | Lost 2 |
| » Starters: Phil Marchildon vs Dizzy Trout | Fifth | 11 out |
| Tuesday, August 3 |
| » Lost to Yankees (57-39), 15-3 | Tiger Stadium (19-25) | 46-50 | Lost 3 |
| » Starters: Spec Shea vs Virgil Trucks | Fifth | 11 out |
| Wednesday, August 4 |
| Future Tiger Johnny Grubb is born in Richmond, VA. |
| Thursday, August 5 |
| » Lost to Yankees (58-39), 2-1 | Tiger Stadium (19-26) | 46-51 | Lost 4 |
| » Starters: Allie Reynolds vs Fred Hutchinson | Fifth | 12 out |
| Friday, August 6 |
| » Defeated Senators (41-58), 1-0 | Tiger Stadium (20-26) | 47-51 | |
| » Starters: Walt Masterson vs Ted Gray | Fifth | 12 out |
| Saturday, August 7 |
| » Lost to Senators (42-58), 3-2 | Tiger Stadium (20-27) | 47-52 | |
| » Starters: Sid Hudson vs Dizzy Trout | Fifth | 12 out |
| Sunday, August 8 |
| » Defeated Senators (42-59), 5-3 | Tiger Stadium (21-27) | 48-52 | |
| » Starters: Early Wynn vs Hal Newhouser | Fifth | 12 out |
| » Defeated Senators (42-60), 6-5 | Tiger Stadium (22-27) | 49-52 | Won 2 |
| » Starters: Forrest Thompson vs Billy Pierce | Fifth | 12 out |
| Monday, August 9 |
| » Lost to Indians (61-39), 6-2 | Tiger Stadium (22-28) | 49-53 | |
| » Starters: Gene Bearden vs Fred Hutchinson | Fifth | 13 out |
| Future Tiger Bill Campbell is born in Highland Park, MI. |
| Tuesday, August 10 |
| » Defeated Indians (61-40), 7-3 | Tiger Stadium (23-28) | 50-53 | |
| » Starters: Bob Feller vs Ted Gray | Fifth | 12 out |
| Wednesday, August 11 |
| » Lost to White Sox (36-69), 2-1 | Comiskey Park I (5-3) | 50-54 | |
| » Starters: Virgil Trucks vs Marino Pieretti | Fifth | 13 out |
| Friday, August 13 |
| » Lost to Browns (43-62), 4-1 | Sportsman's Park III (2-5) | 50-55 | Lost 2 |
| » Starters: Hal Newhouser vs Ned Garver | Fifth | 13½ out |
| Saturday, August 14 |
| » Defeated Browns (43-63), 10-3 | Sportsman's Park III (3-5) | 51-55 | |
| » Starters: Billy Pierce vs Fred Sanford | Fifth | 13½ out |
| Sunday, August 15 |
| » Defeated Browns (43-64), 3-1 | Sportsman's Park III (4-5) | 52-55 | Won 2 |
| » Starters: Fred Hutchinson vs Cliff Fannin | Fifth | 14 out |
| Tuesday, August 17 |
| » Defeated White Sox (36-74), 6-4 | Tiger Stadium (24-28) | 53-55 | Won 3 |
| » Starters: Marino Pieretti vs Ted Gray | Fifth | 14 out |
| Friday, August 20 |
| » Lost to Browns (44-66), 5-4 | Tiger Stadium (24-29) | 53-56 | |
| » Starters: Ned Garver vs Art Houtteman | Fifth | 15½ out |
| Saturday, August 21 |
| » Defeated Browns (44-67), 6-5 | Tiger Stadium (25-29) | 54-56 | |
| » Starters: Cliff Fannin vs Fred Hutchinson | Fifth | 14½ out |
| Sunday, August 22 |
| » Lost to Browns (45-67), 10-1 | Tiger Stadium (25-30) | 54-57 | |
| » Starters: Fred Sanford vs Hal Newhouser | Fifth | 14 out |
| Tuesday, August 24 |
| » Defeated Athletics (68-50), 7-4 | Shibe Park (4-5) | 55-57 | |
| » Starters: Ted Gray vs Lou Brissie | Fifth | 13½ out |
| Wednesday, August 25 |
| » Defeated Athletics (68-51), 10-4 | Shibe Park (5-5) | 56-57 | Won 2 |
| » Starters: Fred Hutchinson vs Phil Marchildon | Fifth | 13 out |
| Thursday, August 26 |
| » Lost to Athletics (69-51), 4-3 | Shibe Park (5-6) | 56-58 | |
| » Starters: Hal Newhouser vs Joe Coleman | Fifth | 13½ out |
| Friday, August 27 |
| » Defeated Senators (46-74), 3-2 | Griffith Stadium (8-2) | 57-58 | |
| » Starters: Billy Pierce vs Walt Masterson | Fifth | 13½ out |
| Saturday, August 28 |
| » Defeated Senators (46-75), 7-5 | Griffith Stadium (9-2) | 58-58 | Won 2 |
| » Starters: Ted Gray vs Milo Candini | Fifth | 13½ out |
| Sunday, August 29 |
| » Defeated Yankees (72-49), 9-6 | Yankee Stadium (5-4) | 59-58 | Won 3 |
| » Starters: Fred Hutchinson vs Bob Porterfield | Fifth | 13½ out |
| » Lost to Yankees (73-49), 11-10 | Yankee Stadium (5-5) | 59-59 | |
| » Starters: Stubby Overmire vs Joe Page | Fifth | 13½ out |
| Monday, August 30 |
| » Lost to Yankees (74-49), 3-0 | Yankee Stadium (5-6) | 59-60 | Lost 2 |
| » Starters: Hal Newhouser vs Spec Shea | Fifth | 14 out |
| Tuesday, August 31 |
| » Lost to Red Sox (76-48), 8-4 | Fenway Park (2-8) | 59-61 | Lost 3 |
| » Starters: Art Houtteman vs Mel Parnell | Fifth | 15 out |
| Wednesday, September 1 |
| » Lost to Red Sox (77-48), 10-1 | Fenway Park (2-9) | 59-62 | Lost 4 |
| » Starters: Virgil Trucks vs Jack Kramer | Fifth | 16 out |
| Friday, September 3 |
| » Defeated White Sox (42-84), 5-2 | Comiskey Park I (6-3) | 60-62 | |
| » Starters: Fred Hutchinson vs Bill Wight | Fifth | 16 out |
| Saturday, September 4 |
| » Defeated White Sox (42-85), 4-3 | Comiskey Park I (7-3) | 61-62 | Won 2 |
| » Starters: Hal Newhouser vs Randy Gumpert | Fifth | 16 out |
| Sunday, September 5 |
| » Lost to White Sox (43-85), 4-3 | Comiskey Park I (7-4) | 61-63 | |
| » Starters: Virgil Trucks vs Al Gettel | Fifth | 17 out |
| Monday, September 6 |
| » Defeated Browns (49-77), 8-1 | Sportsman's Park III (5-5) | 62-63 | |
| » Starters: Ted Gray vs Fred Sanford | Fifth | 18 out |
| » Lost to Browns (50-77), 11-10 | Sportsman's Park III (5-6) | 62-64 | |
| » Starters: Billy Pierce vs Cliff Fannin | Fifth | 18 out |
| Wednesday, September 8 |
| » Lost to Indians (79-53), 8-7 | Cleveland Stadium (4-2) | 62-65 | Lost 2 |
| » Starters: Fred Hutchinson vs Bob Lemon | Fifth | 19 out |
| Thursday, September 9 |
| » Lost to Indians (80-53), 3-2 | Cleveland Stadium (4-3) | 62-66 | Lost 3 |
| » Starters: Hal Newhouser vs Bob Feller | Fifth | 20 out |
| Friday, September 10 |
| » Lost to Indians (81-53), 10-1 | Cleveland Stadium (4-4) | 62-67 | Lost 4 |
| » Starters: Dizzy Trout vs Gene Bearden | Fifth | 20 out |
| Saturday, September 11 |
| » Defeated White Sox (44-90), 4-1 | Tiger Stadium (26-30) | 63-67 | |
| » Starters: Al Gettel vs Ted Gray | Fifth | 20 out |
| » Defeated White Sox (44-91), 6-4 | Tiger Stadium (27-30) | 64-67 | Won 2 |
| » Starters: Frank Papish vs Billy Pierce | Fifth | 20 out |
| Sunday, September 12 |
| » Lost to White Sox (45-91), 5-2 | Tiger Stadium (27-31) | 64-68 | |
| » Starters: Joe Haynes vs Fred Hutchinson | Fifth | 20 out |
| Tuesday, September 14 |
| » Defeated Senators (49-90), 2-1 | Tiger Stadium (28-31) | 65-68 | |
| » Starters: Ray Scarborough vs Hal Newhouser | Fifth | 19½ out |
| » Defeated Senators (49-91), 12-1 | Tiger Stadium (29-31) | 66-68 | Won 2 |
| » Starters: Dick Weik vs Virgil Trucks | Fifth | 19½ out |
| Wednesday, September 15 |
| » Defeated Senators (49-92), 4-2 | Tiger Stadium (30-31) | 67-68 | Won 3 |
| » Starters: Milo Candini vs Lou Kretlow | Fifth | 18½ out |
| » Major-league debuts: Joe Ginsberg (Tigers) |
| Thursday, September 16 |
| » Defeated Yankees (85-53), 2-1 | Tiger Stadium (31-31) | 68-68 | Won 4 |
| » Starters: Vic Raschi vs Fred Hutchinson | Fifth | 18 out |
| » Lost to Yankees (86-53), 8-4 | Tiger Stadium (31-32) | 68-69 | |
| » Starters: Allie Reynolds vs Dizzy Trout | Fifth | 18 out |
| Friday, September 17 |
| » Lost to Yankees (87-53), 13-5 | Tiger Stadium (31-33) | 68-70 | Lost 2 |
| » Starters: Tommy Byrne vs Ted Gray | Fifth | 19 out |
| Saturday, September 18 |
| » Defeated Yankees (87-54), 4-3 | Tiger Stadium (32-33) | 69-70 | |
| » Starters: Ed Lopat vs Hal Newhouser | Fifth | 19 out |
| Sunday, September 19 |
| » Defeated Red Sox (89-53), 4-3 | Tiger Stadium (33-33) | 70-70 | Won 2 |
| » Starters: Ellis Kinder vs Virgil Trucks | Fifth | 17 out |
| » Defeated Red Sox (89-54), 8-6 | Tiger Stadium (34-33) | 71-70 | Won 3 |
| » Starters: Jack Kramer vs Art Houtteman | Fifth | 17 out |
| Monday, September 20 |
| » Lost to Red Sox (90-54), 7-2 | Tiger Stadium (34-34) | 71-71 | |
| » Starters: Mickey Harris vs Fred Hutchinson | Fifth | 18 out |
| Tuesday, September 21 |
| » Lost to Red Sox (91-54), 10-2 | Tiger Stadium (34-35) | 71-72 | Lost 2 |
| » Starters: Mel Parnell vs Ted Gray | Fifth | 19 out |
| Future Tiger Aurelio Lopez is born in Tecamachalco, Mexico. |
| Wednesday, September 22 |
| » Defeated Athletics (83-65), 5-1 | Tiger Stadium (35-35) | 72-72 | |
| » Starters: Phil Marchildon vs Hal Newhouser | Fourth | 18 out |
| Thursday, September 23 |
| » Defeated Athletics (83-66), 8-7 | Tiger Stadium (36-35) | 73-72 | Won 2 |
| » Starters: Wally Holborow vs Ted Gray | Fourth | 17½ out |
| Friday, September 24 |
| » Defeated Indians (91-56), 4-3 | Tiger Stadium (37-35) | 74-72 | Won 3 |
| » Starters: Bob Lemon vs Fred Hutchinson | Third | 16½ out |
| Saturday, September 25 |
| » Lost to Indians (92-56), 9-3 | Tiger Stadium (37-36) | 74-73 | |
| » Starters: Gene Bearden vs Virgil Trucks | Fourth | 17½ out |
| Sunday, September 26 |
| » Lost to Indians (93-56), 4-1 | Tiger Stadium (37-37) | 74-74 | Lost 2 |
| » Starters: Bob Feller vs Hal Newhouser | Fourth | 18½ out |
| Tuesday, September 28 |
| » Lost to Browns (58-90), 5-3 | Tiger Stadium (37-38) | 74-75 | Lost 3 |
| » Starters: Fred Sanford vs Fred Hutchinson | Fourth | 19½ out |
| Wednesday, September 29 |
| » Defeated Browns (58-91), 4-0 | Tiger Stadium (38-38) | 75-75 | |
| » Starters: Ned Garver vs Hal Newhouser | Fourth | 19½ out |
| Thursday, September 30 |
| » Defeated Browns (58-92), 7-2 | Tiger Stadium (39-38) | 76-75 | Won 2 |
| » Starters: Joe Ostrowski vs Ted Gray | Fourth | 19 out |
| Friday, October 1 |
| » Defeated Indians (95-57), 5-3 | Cleveland Stadium (5-4) | 77-75 | Won 3 |
| » Starters: Virgil Trucks vs Bob Lemon | Fourth | 18 out |
| Saturday, October 2 |
| » Lost to Indians (96-57), 8-0 | Cleveland Stadium (5-5) | 77-76 | |
| » Starters: Lou Kretlow vs Gene Bearden | Fifth | 19 out |
| Sunday, October 3 |
| » Defeated Indians (96-58), 7-1 | Cleveland Stadium (6-5) | 78-76 | |
| » Starters: Hal Newhouser vs Bob Feller | Fourth | 18 out |
| » Major-league debuts: Mike Garcia (Indians) |
| Sunday, November 7 |
| Future Tiger Tom Walker is born in Tampa, FL. |
Game information provided by Retrosheet (www.retrosheet.org) |