| Thursday, February 19 |
| Former Senator Bob Groom dies in Belleville, IL at the age of 64. |
| Thursday, March 4 |
| Future Senator Tom Grieve is born in Pittsfield, MA. |
| Monday, April 19 |
| » Lost to Yankees (1-0), 12-4 | Griffith Stadium (0-1) | 0-1 | |
| » Starters: Allie Reynolds vs Early Wynn | Fourth | 1½ out |
| » Major-league debuts: Ramon Garcia and Al Kozar (Senators) |
| Tuesday, April 20 |
| » Defeated Yankees (1-1), 9-1 | Griffith Stadium (1-1) | 1-1 | |
| » Starters: Ed Lopat vs Sid Hudson | Third | 1 out |
| » Major-league debuts: Cliff Mapes (Yankees) |
| Wednesday, April 21 |
| » Defeated Yankees (1-2), 6-3 | Griffith Stadium (2-1) | 2-1 | Won 2 |
| » Starters: Vic Raschi vs Mickey Haefner | Third | ½ out |
| Friday, April 23 |
| » Defeated Athletics (3-1), 5-3 | Shibe Park (1-0) | 3-1 | Won 3 |
| » Starters: Walt Masterson vs Bill McCahan | Second | 1 out |
| Saturday, April 24 |
| » Defeated Athletics (3-2), 3-2 | Shibe Park (2-0) | 4-1 | Won 4 |
| » Starters: Early Wynn vs Phil Marchildon | Second | 1 out |
| Sunday, April 25 |
| » Lost to Athletics (4-2), 4-0 | Shibe Park (2-1) | 4-2 | |
| » Starters: Sid Hudson vs Carl Scheib | Second | 1½ out |
| » Defeated Athletics (4-3), 7-3 | Shibe Park (3-1) | 5-2 | |
| » Starters: Ray Scarborough vs Lou Brissie | Second | 1½ out |
| Monday, April 26 |
| » Lost to Red Sox (2-5), 6-0 | Griffith Stadium (2-2) | 5-3 | |
| » Starters: Mel Parnell vs Mickey Haefner | Second | 1½ out |
| Thursday, April 29 |
| » Lost to Yankees (5-3), 5-4 | Yankee Stadium (0-1) | 5-4 | Lost 2 |
| » Starters: Sid Hudson vs Spec Shea | Third | 2½ out |
| Friday, April 30 |
| » Lost to Athletics (5-5), 3-1 | Griffith Stadium (2-3) | 5-5 | Lost 3 |
| » Starters: Phil Marchildon vs Walt Masterson | Fourth | 3 out |
| Saturday, May 1 |
| » Lost to Athletics (6-5), 5-1 | Griffith Stadium (2-4) | 5-6 | Lost 4 |
| » Starters: Carl Scheib vs Early Wynn | Fifth | 3 out |
| Sunday, May 2 |
| » Lost to Athletics (7-5), 4-3 | Griffith Stadium (2-5) | 5-7 | Lost 5 |
| » Starters: Joe Coleman vs Mickey Haefner | Seventh | 3 out |
| Tuesday, May 4 |
| » Tied White Sox, 3-3 | Griffith Stadium (2-5) | 5-7 | |
| » Starters: Joe Haynes vs Sid Hudson | Seventh | 2½ out |
| Wednesday, May 5 |
| » Defeated White Sox (3-8), 6-0 | Griffith Stadium (3-5) | 6-7 | |
| » Starters: Glen Moulder vs Walt Masterson | Sixth | 2 out |
| Thursday, May 6 |
| » Defeated White Sox (3-9), 5-0 | Griffith Stadium (4-5) | 7-7 | Won 2 |
| » Starters: Bill Wight vs Early Wynn | Fourth | 2 out |
| Friday, May 7 |
| » Lost to Indians (7-4), 8-0 | Griffith Stadium (4-6) | 7-8 | |
| » Starters: Bob Lemon vs Mickey Haefner | Fifth | 2½ out |
| Saturday, May 8 |
| » Lost to Indians (8-4), 6-1 | Griffith Stadium (4-7) | 7-9 | Lost 2 |
| » Starters: Gene Bearden vs Sid Hudson | Seventh | 3½ out |
| Sunday, May 9 |
| » Defeated Browns (6-7), 3-1 | Griffith Stadium (5-7) | 8-9 | |
| » Starters: Ned Garver vs Walt Masterson | Fourth | 3½ out |
| Monday, May 10 |
| » Defeated Browns (6-8), 6-2 | Griffith Stadium (6-7) | 9-9 | Won 2 |
| » Starters: Sam Zoldak vs Early Wynn | Fourth | 3½ out |
| Tuesday, May 11 |
| » Lost to Tigers (9-12), 4-1 | Griffith Stadium (6-8) | 9-10 | |
| » Starters: Virgil Trucks vs Mickey Haefner | Fourth | 4½ out |
| Wednesday, May 12 |
| » Lost to Tigers (10-12), 14-9 | Griffith Stadium (6-9) | 9-11 | Lost 2 |
| » Starters: Hal Newhouser vs Sid Hudson | Fifth | 5½ out |
| Saturday, May 15 |
| » Lost to Red Sox (10-11), 5-0 | Fenway Park (0-1) | 9-12 | Lost 3 |
| » Starters: Walt Masterson vs Joe Dobson | Sixth | 6½ out |
| Sunday, May 16 |
| » Lost to Red Sox (11-11), 14-5 | Fenway Park (0-2) | 9-13 | Lost 4 |
| » Starters: Early Wynn vs Jack Kramer | Seventh | 7 out |
| » Major-league debuts: Dick Welteroth (Senators) |
| Tuesday, May 18 |
| » Defeated White Sox (4-17), 5-4 | Comiskey Park I (1-0) | 10-13 | |
| » Starters: Sid Hudson vs Jim Goodwin | Seventh | 5½ out |
| Wednesday, May 19 |
| » Defeated White Sox (4-18), 4-1 | Comiskey Park I (2-0) | 11-13 | Won 2 |
| » Starters: Walt Masterson vs Joe Haynes | Fifth | 5½ out |
| Thursday, May 20 |
| » Lost to Browns (10-12), 17-7 | Sportsman's Park III (0-1) | 11-14 | |
| » Starters: Early Wynn vs Bryan Stephens | Sixth | 6½ out |
| Friday, May 21 |
| » Lost to Browns (11-12), 4-3 | Sportsman's Park III (0-2) | 11-15 | Lost 2 |
| » Starters: Ray Scarborough vs Sam Zoldak | Seventh | 6½ out |
| Saturday, May 22 |
| » Lost to Browns (12-12), 4-2 | Sportsman's Park III (0-3) | 11-16 | Lost 3 |
| » Starters: Sid Hudson vs Ned Garver | Seventh | 7½ out |
| Sunday, May 23 |
| » Defeated Tigers (15-16), 1-0 | Tiger Stadium (1-0) | 12-16 | |
| » Starters: Walt Masterson vs Virgil Trucks | Sixth | 7 out |
| Monday, May 24 |
| » Lost to Tigers (16-16), 5-2 | Tiger Stadium (1-1) | 12-17 | |
| » Starters: Early Wynn vs Hal Newhouser | Sixth | 7½ out |
| Tuesday, May 25 |
| » Lost to Indians (19-8), 4-0 | Cleveland Stadium (0-1) | 12-18 | Lost 2 |
| » Starters: Mickey Haefner vs Bob Lemon | Sixth | 8½ out |
| Wednesday, May 26 |
| » Defeated Indians (19-9), 2-0 | Cleveland Stadium (1-1) | 13-18 | |
| » Starters: Sid Hudson vs Gene Bearden | Sixth | 7½ out |
| Thursday, May 27 |
| » Lost to Athletics (22-10), 7-3 | Griffith Stadium (6-10) | 13-19 | |
| » Starters: Phil Marchildon vs Walt Masterson | Seventh | 9 out |
| Friday, May 28 |
| » Defeated Red Sox (13-19), 2-1 | Griffith Stadium (7-10) | 14-19 | |
| » Starters: Mel Parnell vs Ray Scarborough | Sixth | 9 out |
| Saturday, May 29 |
| » Defeated Red Sox (13-20), 5-4 | Griffith Stadium (8-10) | 15-19 | Won 2 |
| » Starters: Jack Kramer vs Mickey Haefner | Sixth | 8½ out |
| » Defeated Red Sox (13-21), 7-6 | Griffith Stadium (9-10) | 16-19 | Won 3 |
| » Starters: Earl Johnson vs Dick Welteroth | Sixth | 8½ out |
| Sunday, May 30 |
| » Defeated Red Sox (13-22), 8-1 | Griffith Stadium (10-10) | 17-19 | Won 4 |
| » Starters: Denny Galehouse vs Early Wynn | Sixth | 8 out |
| Monday, May 31 |
| » Lost to Yankees (20-15), 10-0 | Yankee Stadium (0-2) | 17-20 | |
| » Starters: Sid Hudson vs Spec Shea | Sixth | 9 out |
| » Lost to Yankees (21-15), 5-4 | Yankee Stadium (0-3) | 17-21 | Lost 2 |
| » Starters: Marino Pieretti vs Red Embree | Sixth | 9 out |
| Tuesday, June 1 |
| » Defeated Yankees (21-16), 4-1 | Yankee Stadium (1-3) | 18-21 | |
| » Starters: Walt Masterson vs Allie Reynolds | Sixth | 7½ out |
| Wednesday, June 2 |
| » Defeated Indians (23-12), 2-1 | Griffith Stadium (11-10) | 19-21 | Won 2 |
| » Starters: Bob Lemon vs Ray Scarborough | Fifth | 6½ out |
| Friday, June 4 |
| » Lost to Indians (24-12), 5-0 | Griffith Stadium (11-11) | 19-22 | |
| » Starters: Bob Feller vs Mickey Haefner | Fifth | 7½ out |
| Saturday, June 5 |
| » Defeated White Sox (10-28), 3-2 | Griffith Stadium (12-11) | 20-22 | |
| » Starters: Bob Gillespie vs Early Wynn | Fourth | 7½ out |
| Sunday, June 6 |
| » Lost to White Sox (11-28), 10-4 | Griffith Stadium (12-12) | 20-23 | |
| » Starters: Joe Haynes vs Sid Hudson | Fourth | 9½ out |
| » Lost to White Sox (12-28), 11-4 | Griffith Stadium (12-13) | 20-24 | Lost 2 |
| » Starters: Glen Moulder vs Walt Masterson | Fourth | 9½ out |
| Monday, June 7 |
| » Defeated White Sox (12-29), 7-1 | Griffith Stadium (13-13) | 21-24 | |
| » Starters: Bob Gillespie vs Ray Scarborough | Fourth | 9 out |
| Tuesday, June 8 |
| » Defeated Browns (18-24), 6-5 | Griffith Stadium (14-13) | 22-24 | Won 2 |
| » Starters: Bryan Stephens vs Sid Hudson | Third | 9 out |
| Wednesday, June 9 |
| » Defeated Browns (18-25), 5-2 | Griffith Stadium (15-13) | 23-24 | Won 3 |
| » Starters: Cliff Fannin vs Early Wynn | Fourth | 8½ out |
| Thursday, June 10 |
| » Defeated Browns (18-26), 5-4 | Griffith Stadium (16-13) | 24-24 | Won 4 |
| » Starters: Fred Sanford vs Mickey Haefner | Fourth | 7½ out |
| Friday, June 11 |
| » Lost to Tigers (23-25), 7-6 | Griffith Stadium (16-14) | 24-25 | |
| » Starters: Stubby Overmire vs Walt Masterson | Fourth | 8½ out |
| Saturday, June 12 |
| » Lost to Tigers (24-25), 4-1 | Griffith Stadium (16-15) | 24-26 | Lost 2 |
| » Starters: Hal Newhouser vs Ray Scarborough | Fifth | 10 out |
| Sunday, June 13 |
| » Lost to Tigers (25-25), 9-3 | Griffith Stadium (16-16) | 24-27 | Lost 3 |
| » Starters: Dizzy Trout vs Sid Hudson | Fifth | 10½ out |
| » Lost to Tigers (26-25), 9-2 | Griffith Stadium (16-17) | 24-28 | Lost 4 |
| » Starters: Virgil Trucks vs Early Wynn | Fifth | 10½ out |
| Wednesday, June 16 |
| » Lost to Browns (20-29), 6-5 | Sportsman's Park III (0-4) | 24-29 | Lost 5 |
| » Starters: Mickey Haefner vs Fred Sanford | Sixth | 10 out |
| » Major-league debuts: Len Okrie (Senators) |
| Friday, June 18 |
| » Lost to White Sox (15-32), 5-2 | Comiskey Park I (2-1) | 24-30 | Lost 6 |
| » Starters: Walt Masterson vs Joe Haynes | Sixth | 9½ out |
| Saturday, June 19 |
| » Lost to White Sox (16-32), 9-5 | Comiskey Park I (2-2) | 24-31 | Lost 7 |
| » Starters: Early Wynn vs Marino Pieretti | Sixth | 10½ out |
| Sunday, June 20 |
| » Lost to White Sox (17-32), 8-5 | Comiskey Park I (2-3) | 24-32 | Lost 8 |
| » Starters: Ray Scarborough vs Bill Wight | Sixth | 11½ out |
| » Defeated White Sox (17-33), 4-1 | Comiskey Park I (3-3) | 25-32 | |
| » Starters: Sid Hudson vs Al Gettel | Sixth | 11½ out |
| Tuesday, June 22 |
| » Defeated Tigers (28-29), 5-4 | Tiger Stadium (2-1) | 26-32 | Won 2 |
| » Starters: Mickey Haefner vs Art Houtteman | Sixth | 11 out |
| Wednesday, June 23 |
| » Defeated Tigers (28-30), 2-1 | Tiger Stadium (3-1) | 27-32 | Won 3 |
| » Starters: Walt Masterson vs Dizzy Trout | Sixth | 10 out |
| Friday, June 25 |
| » Defeated Indians (35-22), 3-2 | Cleveland Stadium (2-1) | 28-32 | Won 4 |
| » Starters: Early Wynn vs Bob Lemon | Sixth | 8½ out |
| Saturday, June 26 |
| » Lost to Indians (36-22), 5-0 | Cleveland Stadium (2-2) | 28-33 | |
| » Starters: Sid Hudson vs Bob Muncrief | Sixth | 9½ out |
| Sunday, June 27 |
| » Defeated Indians (36-23), 5-2 | Cleveland Stadium (3-2) | 29-33 | |
| » Starters: Ray Scarborough vs Gene Bearden | Sixth | 9½ out |
| » Lost to Indians (37-23), 4-1 | Cleveland Stadium (3-3) | 29-34 | |
| » Starters: Mickey Haefner vs Sam Zoldak | Sixth | 9½ out |
| Tuesday, June 29 |
| » Defeated Athletics (40-27), 5-3 | Shibe Park (4-1) | 30-34 | |
| » Starters: Early Wynn vs Phil Marchildon | Fifth | 9½ out |
| Thursday, July 1 |
| » Lost to Athletics (41-27), 3-2 | Shibe Park (4-2) | 30-35 | |
| » Starters: Ray Scarborough vs Joe Coleman | Sixth | 10 out |
| Friday, July 2 |
| » Defeated Yankees (39-27), 2-1 | Yankee Stadium (2-3) | 31-35 | |
| » Starters: Walt Masterson vs Tommy Byrne | Fifth | 10 out |
| Saturday, July 3 |
| » Lost to Yankees (40-27), 5-3 | Yankee Stadium (2-4) | 31-36 | |
| » Starters: Sid Hudson vs Allie Reynolds | Sixth | 11 out |
| Sunday, July 4 |
| » Lost to Yankees (41-27), 6-5 | Yankee Stadium (2-5) | 31-37 | Lost 2 |
| » Starters: Early Wynn vs Ed Lopat | Sixth | 11½ out |
| Monday, July 5 |
| » Defeated Athletics (43-29), 3-1 | Griffith Stadium (17-17) | 32-37 | |
| » Starters: Joe Coleman vs Mickey Haefner | Sixth | 11½ out |
| » Lost to Athletics (44-29), 12-5 | Griffith Stadium (17-18) | 32-38 | |
| » Starters: Phil Marchildon vs Ray Scarborough | Sixth | 11½ out |
| Tuesday, July 6 |
| » Lost to Athletics (45-29), 5-3 | Griffith Stadium (17-19) | 32-39 | Lost 2 |
| » Starters: Lou Brissie vs Walt Masterson | Sixth | 11½ out |
| Wednesday, July 7 |
| » Defeated Red Sox (36-33), 7-6 | Fenway Park (1-2) | 33-39 | |
| » Starters: Ray Scarborough vs Dave Ferriss | Sixth | 11½ out |
| Thursday, July 8 |
| » Lost to Red Sox (37-33), 4-1 | Fenway Park (1-3) | 33-40 | |
| » Starters: Early Wynn vs Mel Parnell | Sixth | 12½ out |
| Friday, July 9 |
| » Lost to Yankees (43-31), 9-0 | Griffith Stadium (17-20) | 33-41 | Lost 2 |
| » Starters: Ed Lopat vs Sid Hudson | Sixth | 12½ out |
| Saturday, July 10 |
| » Lost to Yankees (44-31), 5-2 | Griffith Stadium (17-21) | 33-42 | Lost 3 |
| » Starters: Vic Raschi vs Mickey Haefner | Sixth | 13 out |
| Sunday, July 11 |
| » Defeated Yankees (44-32), 9-4 | Griffith Stadium (18-21) | 34-42 | |
| » Starters: Tommy Byrne vs Walt Masterson | Sixth | 12½ out |
| Thursday, July 15 |
| » Defeated White Sox (23-50), 4-1 | Griffith Stadium (19-21) | 35-42 | Won 2 |
| » Starters: Bill Wight vs Ray Scarborough | Sixth | 13 out |
| Friday, July 16 |
| » Lost to White Sox (24-50), 3-2 | Griffith Stadium (19-22) | 35-43 | |
| » Starters: Marino Pieretti vs Earl Harrist | Sixth | 13 out |
| Saturday, July 17 |
| » Lost to White Sox (25-50), 9-7 | Griffith Stadium (19-23) | 35-44 | Lost 2 |
| » Starters: Al Gettel vs Sid Hudson | Sixth | 13 out |
| Sunday, July 18 |
| » Lost to Indians (48-30), 2-1 | Griffith Stadium (19-24) | 35-45 | Lost 3 |
| » Starters: Gene Bearden vs Early Wynn | Sixth | 15 out |
| » Lost to Indians (49-30), 6-4 | Griffith Stadium (19-25) | 35-46 | Lost 4 |
| » Starters: Bob Feller vs Mickey Haefner | Sixth | 15 out |
| Monday, July 19 |
| » Lost to Indians (50-30), 7-6 | Griffith Stadium (19-26) | 35-47 | Lost 5 |
| » Starters: Bob Lemon vs Forrest Thompson | Sixth | 16 out |
| Tuesday, July 20 |
| » Defeated Indians (50-31), 2-1 | Griffith Stadium (20-26) | 36-47 | |
| » Starters: Don Black vs Ray Scarborough | Sixth | 15 out |
| Wednesday, July 21 |
| » Defeated Tigers (42-42), 6-1 | Griffith Stadium (21-26) | 37-47 | Won 2 |
| » Starters: Fred Hutchinson vs Walt Masterson | Fifth | 14½ out |
| Thursday, July 22 |
| » Defeated Tigers (42-43), 9-8 | Griffith Stadium (22-26) | 38-47 | Won 3 |
| » Starters: Hal Newhouser vs Early Wynn | Sixth | 13½ out |
| Friday, July 23 |
| » Lost to Tigers (43-43), 11-5 | Griffith Stadium (22-27) | 38-48 | |
| » Starters: Stubby Overmire vs Mickey Haefner | Sixth | 14 out |
| Saturday, July 24 |
| » Lost to Browns (31-52), 13-2 | Griffith Stadium (22-28) | 38-49 | Lost 2 |
| » Starters: Bill Kennedy vs Early Wynn | Sixth | 14½ out |
| Sunday, July 25 |
| » Defeated Browns (31-53), 5-1 | Griffith Stadium (23-28) | 39-49 | |
| » Starters: Fred Sanford vs Ray Scarborough | Sixth | 14½ out |
| » Lost to Browns (32-53), 6-4 | Griffith Stadium (23-29) | 39-50 | |
| » Starters: Blackie Schwamb vs Earl Harrist | Sixth | 14½ out |
| » Major-league debuts: Blackie Schwamb (Browns) |
| Tuesday, July 27 |
| » Lost to White Sox (29-61), 2-1 | Comiskey Park I (3-4) | 39-51 | Lost 2 |
| » Starters: Mickey Haefner vs Bill Wight | Sixth | 15½ out |
| Wednesday, July 28 |
| » Lost to White Sox (30-61), 2-1 | Comiskey Park I (3-5) | 39-52 | Lost 3 |
| » Starters: Sid Hudson vs Marino Pieretti | Sixth | 15½ out |
| Friday, July 30 |
| » Defeated Browns (33-55), 3-2 | Sportsman's Park III (1-4) | 40-52 | |
| » Starters: Ray Scarborough vs Fred Sanford | Sixth | 16 out |
| Saturday, July 31 |
| » Lost to Browns (34-55), 10-8 | Sportsman's Park III (1-5) | 40-53 | |
| » Starters: Walt Masterson vs Blackie Schwamb | Sixth | 16 out |
| Sunday, August 1 |
| » Lost to Browns (35-55), 8-5 | Sportsman's Park III (1-6) | 40-54 | Lost 2 |
| » Starters: Early Wynn vs Cliff Fannin | Sixth | 16 out |
| » Defeated Browns (35-56), 4-3 | Sportsman's Park III (2-6) | 41-54 | |
| » Starters: Earl Harrist vs Ned Garver | Sixth | 16 out |
| Monday, August 2 |
| » Lost to Browns (36-56), 7-5 | Sportsman's Park III (2-7) | 41-55 | |
| » Starters: Sid Hudson vs Bill Kennedy | Sixth | 16½ out |
| Tuesday, August 3 |
| » Lost to Indians (56-38), 5-3 | Cleveland Stadium (3-4) | 41-56 | Lost 2 |
| » Starters: Early Wynn vs Satchel Paige | Sixth | 16½ out |
| Thursday, August 5 |
| » Lost to Indians (57-38), 3-0 | Cleveland Stadium (3-5) | 41-57 | Lost 3 |
| » Starters: Ray Scarborough vs Gene Bearden | Sixth | 17½ out |
| Friday, August 6 |
| » Lost to Tigers (47-51), 1-0 | Tiger Stadium (3-2) | 41-58 | Lost 4 |
| » Starters: Walt Masterson vs Ted Gray | Sixth | 18½ out |
| Saturday, August 7 |
| » Defeated Tigers (47-52), 3-2 | Tiger Stadium (4-2) | 42-58 | |
| » Starters: Sid Hudson vs Dizzy Trout | Sixth | 17½ out |
| Sunday, August 8 |
| » Lost to Tigers (48-52), 5-3 | Tiger Stadium (4-3) | 42-59 | |
| » Starters: Early Wynn vs Hal Newhouser | Sixth | 19½ out |
| » Lost to Tigers (49-52), 6-5 | Tiger Stadium (4-4) | 42-60 | Lost 2 |
| » Starters: Forrest Thompson vs Billy Pierce | Sixth | 19½ out |
| Tuesday, August 10 |
| » Defeated Athletics (63-43), 8-2 | Shibe Park (5-2) | 43-60 | |
| » Starters: Ray Scarborough vs Joe Coleman | Sixth | 19½ out |
| » Lost to Athletics (64-43), 11-2 | Shibe Park (5-3) | 43-61 | |
| » Starters: Walt Masterson vs Bill McCahan | Sixth | 19½ out |
| Wednesday, August 11 |
| » Lost to Athletics (65-43), 8-3 | Shibe Park (5-4) | 43-62 | Lost 2 |
| » Starters: Sid Hudson vs Phil Marchildon | Sixth | 20½ out |
| Friday, August 13 |
| » Lost to Red Sox (63-44), 6-2 | Griffith Stadium (23-30) | 43-63 | Lost 3 |
| » Starters: Mel Parnell vs Early Wynn | Seventh | 21 out |
| Former Senator Nig Perrine dies in Kansas City, MO at the age of 64. |
| Saturday, August 14 |
| » Lost to Red Sox (64-44), 4-3 | Griffith Stadium (23-31) | 43-64 | Lost 4 |
| » Starters: Joe Dobson vs Mickey Haefner | Seventh | 22 out |
| Sunday, August 15 |
| » Defeated Red Sox (64-45), 5-4 | Griffith Stadium (24-31) | 44-64 | |
| » Starters: Jack Kramer vs Ray Scarborough | Sixth | 23 out |
| » Lost to Red Sox (65-45), 8-7 | Griffith Stadium (24-32) | 44-65 | |
| » Starters: Ellis Kinder vs Walt Masterson | Sixth | 23 out |
| Tuesday, August 17 |
| » Lost to Yankees (62-46), 8-1 | Griffith Stadium (24-33) | 44-66 | Lost 2 |
| » Starters: Bob Porterfield vs Sid Hudson | Sixth | 24 out |
| » Major-league debuts: Jim Clark (Senators) |
| Wednesday, August 18 |
| » Lost to Yankees (63-46), 4-1 | Griffith Stadium (24-34) | 44-67 | Lost 3 |
| » Starters: Vic Raschi vs Mickey Haefner | Sixth | 25 out |
| Thursday, August 19 |
| » Lost to Yankees (64-46), 8-1 | Griffith Stadium (24-35) | 44-68 | Lost 4 |
| » Starters: Allie Reynolds vs Early Wynn | Seventh | 25½ out |
| Friday, August 20 |
| » Lost to Red Sox (67-46), 5-4 | Fenway Park (1-4) | 44-69 | Lost 5 |
| » Starters: Ray Scarborough vs Mel Parnell | Seventh | 27 out |
| » Lost to Red Sox (68-46), 10-4 | Fenway Park (1-5) | 44-70 | Lost 6 |
| » Starters: Earl Harrist vs Jack Kramer | Seventh | 27 out |
| Saturday, August 21 |
| » Lost to Red Sox (69-46), 10-6 | Fenway Park (1-6) | 44-71 | Lost 7 |
| » Starters: Dick Welteroth vs Ellis Kinder | Seventh | 27 out |
| Sunday, August 22 |
| » Lost to Red Sox (70-46), 4-1 | Fenway Park (1-7) | 44-72 | Lost 8 |
| » Starters: Forrest Thompson vs Mickey Harris | Seventh | 26½ out |
| Tuesday, August 24 |
| » Lost to Browns (46-67), 6-5 | Griffith Stadium (24-36) | 44-73 | Lost 9 |
| » Starters: Bill Kennedy vs Early Wynn | Seventh | 27 out |
| Wednesday, August 25 |
| » Defeated Browns (46-68), 14-6 | Griffith Stadium (25-36) | 45-73 | |
| » Starters: Joe Ostrowski vs Ray Scarborough | Seventh | 26½ out |
| Thursday, August 26 |
| » Defeated Browns (46-69), 8-7 | Griffith Stadium (26-36) | 46-73 | Won 2 |
| » Starters: Cliff Fannin vs Sid Hudson | Seventh | 26 out |
| Friday, August 27 |
| » Lost to Tigers (57-58), 3-2 | Griffith Stadium (26-37) | 46-74 | |
| » Starters: Billy Pierce vs Walt Masterson | Seventh | 27 out |
| Saturday, August 28 |
| » Lost to Tigers (58-58), 7-5 | Griffith Stadium (26-38) | 46-75 | Lost 2 |
| » Starters: Ted Gray vs Milo Candini | Seventh | 28 out |
| Sunday, August 29 |
| » Lost to Indians (73-49), 6-0 | Griffith Stadium (26-39) | 46-76 | Lost 3 |
| » Starters: Bob Lemon vs Forrest Thompson | Seventh | 28 out |
| » Defeated Indians (73-50), 5-2 | Griffith Stadium (27-39) | 47-76 | |
| » Starters: Don Black vs Early Wynn | Seventh | 28 out |
| Monday, August 30 |
| » Lost to Indians (74-50), 10-1 | Griffith Stadium (27-40) | 47-77 | |
| » Starters: Satchel Paige vs Ray Scarborough | Seventh | 28½ out |
| Tuesday, August 31 |
| » Defeated White Sox (42-82), 7-1 | Griffith Stadium (28-40) | 48-77 | |
| » Starters: Ike Pearson vs Sid Hudson | Seventh | 28½ out |
| Wednesday, September 1 |
| » Defeated White Sox (42-83), 5-4 | Griffith Stadium (29-40) | 49-77 | Won 2 |
| » Starters: Marino Pieretti vs Walt Masterson | Sixth | 28½ out |
| Friday, September 3 |
| » Lost to Yankees (77-49), 6-2 | Yankee Stadium (2-6) | 49-78 | |
| » Starters: Forrest Thompson vs Ed Lopat | Seventh | 30 out |
| » Lost to Yankees (78-49), 5-2 | Yankee Stadium (2-7) | 49-79 | Lost 2 |
| » Starters: Early Wynn vs Spec Shea | Seventh | 30 out |
| Saturday, September 4 |
| » Lost to Yankees (79-49), 9-7 | Yankee Stadium (2-8) | 49-80 | Lost 3 |
| » Starters: Milo Candini vs Bob Porterfield | Seventh | 31 out |
| Sunday, September 5 |
| » Lost to Yankees (80-49), 5-3 | Yankee Stadium (2-9) | 49-81 | Lost 4 |
| » Starters: Sid Hudson vs Allie Reynolds | Seventh | 32 out |
| Monday, September 6 |
| » Lost to Red Sox (81-48), 14-6 | Griffith Stadium (29-41) | 49-82 | Lost 5 |
| » Starters: Mel Parnell vs Mickey Haefner | Seventh | 34 out |
| » Lost to Red Sox (82-48), 2-1 | Griffith Stadium (29-42) | 49-83 | Lost 6 |
| » Starters: Jack Kramer vs Walt Masterson | Seventh | 34 out |
| Wednesday, September 8 |
| » Lost to Athletics (75-59), 10-7 | Griffith Stadium (29-43) | 49-84 | Lost 7 |
| » Starters: Alex Kellner vs Early Wynn | Seventh | 35½ out |
| » Lost to Athletics (76-59), 5-2 | Griffith Stadium (29-44) | 49-85 | Lost 8 |
| » Starters: Carl Scheib vs Dick Weik | Seventh | 35½ out |
| » Major-league debuts: Dick Weik (Senators) |
| Friday, September 10 |
| » Lost to Athletics (77-59), 9-6 | Griffith Stadium (29-45) | 49-86 | Lost 9 |
| » Starters: Dick Fowler vs Sid Hudson | Seventh | 36½ out |
| » Lost to Athletics (78-59), 3-0 | Griffith Stadium (29-46) | 49-87 | Lost 10 |
| » Starters: Phil Marchildon vs Milo Candini | Seventh | 36½ out |
| Saturday, September 11 |
| » Lost to Yankees (83-52), 6-3 | Griffith Stadium (29-47) | 49-88 | Lost 11 |
| » Starters: Allie Reynolds vs Forrest Thompson | Seventh | 38 out |
| Sunday, September 12 |
| » Lost to Yankees (84-52), 10-5 | Griffith Stadium (29-48) | 49-89 | Lost 12 |
| » Starters: Bob Porterfield vs Walt Masterson | Seventh | 38 out |
| Tuesday, September 14 |
| » Lost to Tigers (65-68), 2-1 | Tiger Stadium (4-5) | 49-90 | Lost 13 |
| » Starters: Ray Scarborough vs Hal Newhouser | Seventh | 39½ out |
| » Lost to Tigers (66-68), 12-1 | Tiger Stadium (4-6) | 49-91 | Lost 14 |
| » Starters: Dick Weik vs Virgil Trucks | Seventh | 39½ out |
| Wednesday, September 15 |
| » Lost to Tigers (67-68), 4-2 | Tiger Stadium (4-7) | 49-92 | Lost 15 |
| » Starters: Milo Candini vs Lou Kretlow | Seventh | 39½ out |
| » Major-league debuts: Joe Ginsberg (Tigers) |
| Thursday, September 16 |
| » Lost to Indians (85-55), 6-3 | Cleveland Stadium (3-6) | 49-93 | Lost 16 |
| » Starters: Sid Hudson vs Gene Bearden | Seventh | 39½ out |
| Friday, September 17 |
| » Lost to Indians (86-55), 4-1 | Cleveland Stadium (3-7) | 49-94 | Lost 17 |
| » Starters: Walt Masterson vs Bob Feller | Seventh | 40½ out |
| Saturday, September 18 |
| » Lost to Indians (87-55), 10-1 | Cleveland Stadium (3-8) | 49-95 | Lost 18 |
| » Starters: Early Wynn vs Sam Zoldak | Seventh | 41½ out |
| Sunday, September 19 |
| » Defeated White Sox (46-95), 10-7 | Comiskey Park I (4-5) | 50-95 | |
| » Starters: Ray Scarborough vs Joe Haynes | Seventh | 39½ out |
| » Defeated White Sox (46-96), 8-6 | Comiskey Park I (5-5) | 51-95 | Won 2 |
| » Starters: Forrest Thompson vs Marino Pieretti | Seventh | 39½ out |
| Wednesday, September 22 |
| » Defeated Browns (56-87), 5-4 | Sportsman's Park III (3-7) | 52-95 | Won 3 |
| » Starters: Sid Hudson vs Cliff Fannin | Sixth | 39½ out |
| Thursday, September 23 |
| » Defeated Browns (56-88), 9-8 | Sportsman's Park III (4-7) | 53-95 | Won 4 |
| » Starters: Ray Scarborough vs Fred Sanford | Sixth | 39 out |
| Saturday, September 25 |
| » Major-league debuts: Joe Collins (Yankees) |
| Tuesday, September 28 |
| » Defeated Red Sox (92-58), 4-2 | Fenway Park (2-7) | 54-95 | Won 5 |
| » Starters: Ray Scarborough vs Joe Dobson | Sixth | 39½ out |
| Wednesday, September 29 |
| » Lost to Red Sox (93-58), 5-1 | Fenway Park (2-8) | 54-96 | |
| » Starters: Walt Masterson vs Ellis Kinder | Sixth | 40½ out |
| Thursday, September 30 |
| » Lost to Red Sox (94-58), 7-3 | Fenway Park (2-9) | 54-97 | Lost 2 |
| » Starters: Early Wynn vs Mel Parnell | Sixth | 41 out |
| Saturday, October 2 |
| » Defeated Athletics (84-69), 7-1 | Shibe Park (6-4) | 55-97 | |
| » Starters: Dick Weik vs Bill McCahan | Seventh | 40½ out |
| Sunday, October 3 |
| » Defeated Athletics (84-70), 7-2 | Shibe Park (7-4) | 56-97 | Won 2 |
| » Starters: Ray Scarborough vs Phil Marchildon | Sixth | 39½ out |
| Friday, October 8 |
| Former Senator Al Orth dies in Lynchburg, VA at the age of 77. |
| Tuesday, October 26 |
| Future Senator Toby Harrah is born in Sissonville, WV. |
| Thursday, November 4 |
| Former Senator Jake Powell dies in Washington, DC at the age of 41. |
Game information provided by Retrosheet (www.retrosheet.org) |
