| Sunday, January 4 |
| Former Red Sox Biff Schlitzer dies in Wellesley Hills, MA at the age of 64. |
| Friday, January 30 |
| Former Red Sox Herb Pennock dies in New York, NY at the age of 54. |
| Tuesday, March 9 |
| Future Red Sox John Curtis is born in Newton, MA. |
| Thursday, March 25 |
| Future Red Sox Mike Nagy is born in Bronx, NY. |
| Monday, April 19 |
| » Lost to Athletics (1-0), 5-4 | Fenway Park (0-1) | 0-1 | |
| » Starters: Phil Marchildon vs Joe Dobson | Fifth | 2 out |
| » Lost to Athletics (2-0), 4-2 | Fenway Park (0-2) | 0-2 | Lost 2 |
| » Starters: Lou Brissie vs Denny Galehouse | Fifth | 2 out |
| Future Red Sox Rick Miller is born in Grand Rapids, MI. |
| Thursday, April 22 |
| » Lost to Athletics (3-0), 5-3 | Fenway Park (0-3) | 0-3 | Lost 3 |
| » Starters: Joe Coleman vs Dave Ferriss | Sixth | 3 out |
| Friday, April 23 |
| » Defeated Yankees (1-3), 4-0 | Yankee Stadium (1-0) | 1-3 | |
| » Starters: Mickey Harris vs Spec Shea | Third | 2 out |
| Saturday, April 24 |
| » Lost to Yankees (2-3), 7-2 | Yankee Stadium (1-1) | 1-4 | |
| » Starters: Joe Dobson vs Allie Reynolds | Sixth | 3 out |
| » Major-league debuts: Mickey McDermott (Red Sox) |
| Sunday, April 25 |
| » Lost to Yankees (3-3), 5-4 | Yankee Stadium (1-2) | 1-5 | Lost 2 |
| » Starters: Windy McCall vs Ed Lopat | Sixth | 4 out |
| » Major-league debuts: Windy McCall (Red Sox) |
| Monday, April 26 |
| » Defeated Senators (5-3), 6-0 | Griffith Stadium (1-0) | 2-5 | |
| » Starters: Mel Parnell vs Mickey Haefner | Seventh | 4 out |
| Thursday, April 29 |
| » Defeated Athletics (4-5), 11-5 | Shibe Park (1-0) | 3-5 | Won 2 |
| » Starters: Earl Johnson vs Bill McCahan | Seventh | 4 out |
| Friday, April 30 |
| » Lost to Yankees (6-3), 6-0 | Fenway Park (0-4) | 3-6 | |
| » Starters: Allie Reynolds vs Mickey Harris | Sixth | 4½ out |
| Saturday, May 1 |
| » Defeated Yankees (6-4), 8-6 | Fenway Park (1-4) | 4-6 | |
| » Starters: Ed Lopat vs Jack Kramer | Seventh | 3½ out |
| Sunday, May 2 |
| » Defeated Yankees (6-5), 7-1 | Fenway Park (2-4) | 5-6 | Won 2 |
| » Starters: Karl Drews vs Joe Dobson | Sixth | 2½ out |
| Tuesday, May 4 |
| » Defeated Tigers (6-8), 6-3 | Fenway Park (3-4) | 6-6 | Won 3 |
| » Starters: Art Houtteman vs Dave Ferriss | Fifth | 1½ out |
| Wednesday, May 5 |
| » Defeated Tigers (6-9), 4-3 | Fenway Park (4-4) | 7-6 | Won 4 |
| » Starters: Virgil Trucks vs Mel Parnell | Fourth | 2 out |
| Thursday, May 6 |
| » Lost to Tigers (7-9), 8-3 | Fenway Park (4-5) | 7-7 | |
| » Starters: Hal Newhouser vs Jack Kramer | Fourth | 2 out |
| Saturday, May 8 |
| » Lost to Browns (6-6), 9-4 | Fenway Park (4-6) | 7-8 | Lost 2 |
| » Starters: Fred Sanford vs Mickey Harris | Fifth | 3 out |
| Sunday, May 9 |
| » Lost to Indians (9-4), 4-1 | Fenway Park (4-7) | 7-9 | Lost 3 |
| » Starters: Bob Feller vs Joe Dobson | Sixth | 4½ out |
| » Lost to Indians (10-4), 9-5 | Fenway Park (4-8) | 7-10 | Lost 4 |
| » Starters: Don Black vs Ellis Kinder | Sixth | 4½ out |
| Monday, May 10 |
| » Lost to Indians (11-4), 12-7 | Fenway Park (4-9) | 7-11 | Lost 5 |
| » Starters: Al Gettel vs Dave Ferriss | Seventh | 5½ out |
| Tuesday, May 11 |
| » Defeated White Sox (3-13), 8-0 | Fenway Park (5-9) | 8-11 | |
| » Starters: Glen Moulder vs Jack Kramer | Sixth | 5½ out |
| Wednesday, May 12 |
| » Defeated White Sox (3-14), 6-5 | Fenway Park (6-9) | 9-11 | Won 2 |
| » Starters: Orval Grove vs Mel Parnell | Fifth | 5½ out |
| Saturday, May 15 |
| » Defeated Senators (9-12), 5-0 | Fenway Park (7-9) | 10-11 | Won 3 |
| » Starters: Walt Masterson vs Joe Dobson | Fourth | 5½ out |
| Sunday, May 16 |
| » Defeated Senators (9-13), 14-5 | Fenway Park (8-9) | 11-11 | Won 4 |
| » Starters: Early Wynn vs Jack Kramer | Fourth | 5 out |
| » Major-league debuts: Dick Welteroth (Senators) |
| Tuesday, May 18 |
| » Lost to Tigers (12-14), 10-7 | Tiger Stadium (0-1) | 11-12 | |
| » Starters: Dave Ferriss vs Virgil Trucks | Fourth | 4½ out |
| Wednesday, May 19 |
| » Lost to Tigers (13-14), 4-1 | Tiger Stadium (0-2) | 11-13 | Lost 2 |
| » Starters: Ellis Kinder vs Hal Newhouser | Fifth | 5½ out |
| Thursday, May 20 |
| » Lost to Indians (16-6), 13-4 | Cleveland Stadium (0-1) | 11-14 | Lost 3 |
| » Starters: Mickey Harris vs Bob Lemon | Sixth | 6½ out |
| Friday, May 21 |
| » Defeated Indians (16-7), 11-5 | Cleveland Stadium (1-1) | 12-14 | |
| » Starters: Joe Dobson vs Bill Kennedy | Sixth | 5½ out |
| Saturday, May 22 |
| » Lost to Indians (17-7), 7-0 | Cleveland Stadium (1-2) | 12-15 | |
| » Starters: Jack Kramer vs Gene Bearden | Sixth | 6½ out |
| Sunday, May 23 |
| » Lost to White Sox (6-20), 4-3 | Comiskey Park I (0-1) | 12-16 | Lost 2 |
| » Starters: Earl Johnson vs Joe Haynes | Seventh | 7½ out |
| » Lost to White Sox (7-20), 4-3 | Comiskey Park I (0-2) | 12-17 | Lost 3 |
| » Starters: Denny Galehouse vs Glen Moulder | Seventh | 7½ out |
| Future Red Sox Reggie Cleveland is born in Swift Current, SK. |
| Tuesday, May 25 |
| » Lost to Browns (13-14), 9-4 | Sportsman's Park III (0-1) | 12-18 | Lost 4 |
| » Starters: Ellis Kinder vs Sam Zoldak | Sixth | 8½ out |
| Wednesday, May 26 |
| » Defeated Browns (13-15), 5-3 | Sportsman's Park III (1-1) | 13-18 | |
| » Starters: Joe Dobson vs Ned Garver | Sixth | 7½ out |
| Friday, May 28 |
| » Lost to Senators (14-19), 2-1 | Griffith Stadium (1-1) | 13-19 | |
| » Starters: Mel Parnell vs Ray Scarborough | Seventh | 9½ out |
| Saturday, May 29 |
| » Lost to Senators (15-19), 5-4 | Griffith Stadium (1-2) | 13-20 | Lost 2 |
| » Starters: Jack Kramer vs Mickey Haefner | Seventh | 11 out |
| » Lost to Senators (16-19), 7-6 | Griffith Stadium (1-3) | 13-21 | Lost 3 |
| » Starters: Earl Johnson vs Dick Welteroth | Seventh | 11 out |
| Sunday, May 30 |
| » Lost to Senators (17-19), 8-1 | Griffith Stadium (1-4) | 13-22 | Lost 4 |
| » Starters: Denny Galehouse vs Early Wynn | Seventh | 11½ out |
| Monday, May 31 |
| » Defeated Athletics (25-12), 7-0 | Shibe Park (2-0) | 14-22 | |
| » Starters: Joe Dobson vs Lou Brissie | Seventh | 11½ out |
| » Lost to Athletics (26-12), 2-1 | Shibe Park (2-1) | 14-23 | |
| » Starters: Mickey Harris vs Joe Coleman | Seventh | 11½ out |
| Tuesday, June 1 |
| » Defeated Athletics (26-13), 8-1 | Shibe Park (3-1) | 15-23 | |
| » Starters: Ellis Kinder vs Phil Marchildon | Seventh | 10 out |
| Wednesday, June 2 |
| » Lost to Browns (17-17), 3-1 | Fenway Park (8-10) | 15-24 | |
| » Starters: Fred Sanford vs Mel Parnell | Sixth | 10 out |
| Thursday, June 3 |
| » Defeated Browns (17-18), 3-2 | Fenway Park (9-10) | 16-24 | |
| » Starters: Ned Garver vs Jack Kramer | Seventh | 9½ out |
| Friday, June 4 |
| » Defeated Browns (17-19), 10-4 | Fenway Park (10-10) | 17-24 | Won 2 |
| » Starters: Bryan Stephens vs Joe Dobson | Seventh | 9 out |
| » Defeated Browns (17-20), 7-2 | Fenway Park (11-10) | 18-24 | Won 3 |
| » Starters: Sam Zoldak vs Denny Galehouse | Seventh | 9 out |
| Sunday, June 6 |
| » Defeated Tigers (20-23), 5-4 | Fenway Park (12-10) | 19-24 | Won 4 |
| » Starters: Virgil Trucks vs Mickey Harris | Fourth | 9½ out |
| » Defeated Tigers (20-24), 12-4 | Fenway Park (13-10) | 20-24 | Won 5 |
| » Starters: Art Houtteman vs Ellis Kinder | Fourth | 9½ out |
| Tuesday, June 8 |
| » Lost to Indians (28-12), 2-0 | Fenway Park (13-11) | 20-25 | |
| » Starters: Gene Bearden vs Mel Parnell | Fifth | 10½ out |
| Thursday, June 10 |
| » Defeated Indians (28-13), 15-7 | Fenway Park (14-11) | 21-25 | |
| » Starters: Bob Feller vs Joe Dobson | Sixth | 9½ out |
| Friday, June 11 |
| » Defeated White Sox (12-31), 12-4 | Fenway Park (15-11) | 22-25 | Won 2 |
| » Starters: Frank Papish vs Jack Kramer | Sixth | 9½ out |
| Saturday, June 12 |
| » Lost to White Sox (13-31), 5-3 | Fenway Park (15-12) | 22-26 | |
| » Starters: Al Gettel vs Mickey Harris | Sixth | 11 out |
| Tuesday, June 15 |
| » Defeated Indians (31-15), 7-3 | Cleveland Stadium (2-2) | 23-26 | |
| » Starters: Mel Parnell vs Bob Lemon | Fifth | 9½ out |
| Wednesday, June 16 |
| » Defeated Indians (31-16), 7-4 | Cleveland Stadium (3-2) | 24-26 | Won 2 |
| » Starters: Joe Dobson vs Bob Feller | Fifth | 8½ out |
| Thursday, June 17 |
| » Defeated Indians (31-17), 8-6 | Cleveland Stadium (4-2) | 25-26 | Won 3 |
| » Starters: Denny Galehouse vs Don Black | Fifth | 7½ out |
| Saturday, June 19 |
| » Defeated Tigers (28-27), 9-7 | Tiger Stadium (1-2) | 26-26 | Won 4 |
| » Starters: Jack Kramer vs Virgil Trucks | Fifth | 7 out |
| Sunday, June 20 |
| » Defeated Tigers (28-28), 8-3 | Tiger Stadium (2-2) | 27-26 | Won 5 |
| » Starters: Mel Parnell vs Hal Newhouser | Fourth | 7½ out |
| Tuesday, June 22 |
| » Defeated White Sox (17-34), 11-6 | Comiskey Park I (1-2) | 28-26 | Won 6 |
| » Starters: Joe Dobson vs Glen Moulder | Fourth | 7 out |
| Thursday, June 24 |
| » Lost to White Sox (18-34), 3-1 | Comiskey Park I (1-3) | 28-27 | |
| » Starters: Ellis Kinder vs Bill Wight | Fourth | 6 out |
| » Defeated White Sox (18-35), 8-5 | Comiskey Park I (2-3) | 29-27 | |
| » Starters: Jack Kramer vs Joe Haynes | Fourth | 6 out |
| Friday, June 25 |
| » Lost to Browns (23-35), 9-6 | Sportsman's Park III (1-2) | 29-28 | |
| » Starters: Mel Parnell vs Bryan Stephens | Fourth | 6 out |
| Sunday, June 27 |
| » Defeated Browns (23-36), 2-0 | Sportsman's Park III (2-2) | 30-28 | |
| » Starters: Joe Dobson vs Bill Kennedy | Fourth | 5½ out |
| » Defeated Browns (23-37), 6-3 | Sportsman's Park III (3-2) | 31-28 | Won 2 |
| » Starters: Dave Ferriss vs Ned Garver | Fourth | 5½ out |
| Tuesday, June 29 |
| » Lost to Yankees (38-25), 7-0 | Yankee Stadium (1-3) | 31-29 | |
| » Starters: Mel Parnell vs Ed Lopat | Fourth | 6½ out |
| Wednesday, June 30 |
| » Defeated Yankees (38-26), 7-3 | Yankee Stadium (2-3) | 32-29 | |
| » Starters: Jack Kramer vs Vic Raschi | Fourth | 6½ out |
| Thursday, July 1 |
| » Lost to Yankees (39-26), 10-7 | Yankee Stadium (2-4) | 32-30 | |
| » Starters: Mickey Harris vs Frank Hiller | Fourth | 6½ out |
| Friday, July 2 |
| » Lost to Athletics (42-27), 4-2 | Fenway Park (15-13) | 32-31 | Lost 2 |
| » Starters: Lou Brissie vs Joe Dobson | Fourth | 7½ out |
| Saturday, July 3 |
| » Lost to Athletics (43-27), 8-2 | Fenway Park (15-14) | 32-32 | Lost 3 |
| » Starters: Dick Fowler vs Dave Ferriss | Fourth | 8½ out |
| Sunday, July 4 |
| » Defeated Athletics (43-28), 19-5 | Fenway Park (16-14) | 33-32 | |
| » Starters: Carl Scheib vs Ellis Kinder | Fourth | 8 out |
| Monday, July 5 |
| » Defeated Yankees (41-28), 6-5 | Fenway Park (17-14) | 34-32 | Won 2 |
| » Starters: Vic Raschi vs Jack Kramer | Fourth | 7 out |
| » Defeated Yankees (41-29), 8-7 | Fenway Park (18-14) | 35-32 | Won 3 |
| » Starters: Spec Shea vs Mickey Harris | Fourth | 7 out |
| Tuesday, July 6 |
| » Defeated Yankees (41-30), 2-1 | Fenway Park (19-14) | 36-32 | Won 4 |
| » Starters: Frank Hiller vs Joe Dobson | Fourth | 6 out |
| Wednesday, July 7 |
| » Lost to Senators (33-39), 7-6 | Fenway Park (19-15) | 36-33 | |
| » Starters: Ray Scarborough vs Dave Ferriss | Fourth | 7 out |
| Future Red Sox Bob Gallagher is born in Newton, MA. |
| Thursday, July 8 |
| » Defeated Senators (33-40), 4-1 | Fenway Park (20-15) | 37-33 | |
| » Starters: Early Wynn vs Mel Parnell | Fourth | 7 out |
| Friday, July 9 |
| » Lost to Athletics (47-30), 8-7 | Shibe Park (3-2) | 37-34 | |
| » Starters: Ellis Kinder vs Joe Coleman | Fourth | 7 out |
| Saturday, July 10 |
| » Defeated Athletics (47-31), 4-0 | Shibe Park (4-2) | 38-34 | |
| » Starters: Jack Kramer vs Bill McCahan | Fourth | 6½ out |
| Sunday, July 11 |
| » Defeated Athletics (47-32), 9-8 | Shibe Park (5-2) | 39-34 | Won 2 |
| » Starters: Joe Dobson vs Lou Brissie | Fourth | 6½ out |
| » Lost to Athletics (48-32), 7-5 | Shibe Park (5-3) | 39-35 | |
| » Starters: Mickey Harris vs Dick Fowler | Fourth | 6½ out |
| Thursday, July 15 |
| » Defeated Tigers (39-38), 13-5 | Fenway Park (21-15) | 40-35 | |
| » Starters: Fred Hutchinson vs Jack Kramer | Fourth | 6½ out |
| » Defeated Tigers (39-39), 3-1 | Fenway Park (22-15) | 41-35 | Won 2 |
| » Starters: Dizzy Trout vs Mel Parnell | Fourth | 6½ out |
| Friday, July 16 |
| » Defeated Tigers (39-40), 5-3 | Fenway Park (23-15) | 42-35 | Won 3 |
| » Starters: Art Houtteman vs Joe Dobson | Fourth | 5½ out |
| Saturday, July 17 |
| » Lost to Tigers (40-40), 3-1 | Fenway Park (23-16) | 42-36 | |
| » Starters: Virgil Trucks vs Ellis Kinder | Fourth | 5½ out |
| Sunday, July 18 |
| » Defeated Browns (29-48), 12-5 | Fenway Park (24-16) | 43-36 | |
| » Starters: Bill Kennedy vs Dave Ferriss | Fourth | 5½ out |
| » Defeated Browns (29-49), 7-6 | Fenway Park (25-16) | 44-36 | Won 2 |
| » Starters: Ray Shore vs Mickey Harris | Fourth | 5½ out |
| Monday, July 19 |
| » Defeated Browns (29-50), 4-1 | Fenway Park (26-16) | 45-36 | Won 3 |
| » Starters: Fred Sanford vs Mel Parnell | Fourth | 5½ out |
| Tuesday, July 20 |
| » Defeated Browns (29-51), 8-3 | Fenway Park (27-16) | 46-36 | Won 4 |
| » Starters: Bill Kennedy vs Jack Kramer | Fourth | 4½ out |
| Wednesday, July 21 |
| » Defeated White Sox (27-54), 3-1 | Fenway Park (28-16) | 47-36 | Won 5 |
| » Starters: Al Gettel vs Joe Dobson | Third | 3½ out |
| » Defeated White Sox (27-55), 10-9 | Fenway Park (29-16) | 48-36 | Won 6 |
| » Starters: Frank Papish vs Dave Ferriss | Third | 3½ out |
| Thursday, July 22 |
| » Defeated White Sox (27-56), 3-0 | Fenway Park (30-16) | 49-36 | Won 7 |
| » Starters: Bob Gillespie vs Denny Galehouse | Third | 2 out |
| » Defeated White Sox (27-57), 5-3 | Fenway Park (31-16) | 50-36 | Won 8 |
| » Starters: Howie Judson vs Ellis Kinder | Third | 2 out |
| Friday, July 23 |
| » Defeated White Sox (27-58), 13-1 | Fenway Park (32-16) | 51-36 | Won 9 |
| » Starters: Bill Wight vs Mickey Harris | Third | 1½ out |
| Saturday, July 24 |
| » Defeated Indians (51-34), 6-5 | Fenway Park (33-16) | 52-36 | Won 10 |
| » Starters: Bob Lemon vs Jack Kramer | Second | 1½ out |
| » Defeated Indians (51-35), 2-1 | Fenway Park (34-16) | 53-36 | Won 11 |
| » Starters: Sam Zoldak vs Mel Parnell | Second | 1½ out |
| Sunday, July 25 |
| » Defeated Indians (51-36), 3-0 | Fenway Park (35-16) | 54-36 | Won 12 |
| » Starters: Steve Gromek vs Joe Dobson | First | -- |
| Tuesday, July 27 |
| » Defeated Tigers (44-46), 8-0 | Tiger Stadium (3-2) | 55-36 | Won 13 |
| » Starters: Ellis Kinder vs Hal Newhouser | First | -- |
| Wednesday, July 28 |
| » Lost to Tigers (45-46), 13-0 | Tiger Stadium (3-3) | 55-37 | |
| » Starters: Denny Galehouse vs Dizzy Trout | First | -- |
| Thursday, July 29 |
| » Defeated Tigers (45-47), 8-1 | Tiger Stadium (4-3) | 56-37 | |
| » Starters: Jack Kramer vs Virgil Trucks | First | -- |
| Friday, July 30 |
| » Defeated Indians (52-38), 8-7 | Cleveland Stadium (5-2) | 57-37 | Won 2 |
| » Starters: Mel Parnell vs Gene Bearden | First | -- |
| Saturday, July 31 |
| » Lost to Indians (53-38), 10-9 | Cleveland Stadium (5-3) | 57-38 | |
| » Starters: Joe Dobson vs Bob Feller | First | -- |
| Sunday, August 1 |
| » Lost to Indians (54-38), 12-2 | Cleveland Stadium (5-4) | 57-39 | Lost 2 |
| » Starters: Ellis Kinder vs Bob Lemon | Fourth | 1 out |
| » Lost to Indians (55-38), 6-1 | Cleveland Stadium (5-5) | 57-40 | Lost 3 |
| » Starters: Mickey Harris vs Sam Zoldak | Fourth | 1 out |
| Tuesday, August 3 |
| » Defeated Browns (36-57), 15-8 | Sportsman's Park III (4-2) | 58-40 | |
| » Starters: Jack Kramer vs Fred Sanford | Third | 2 out |
| Wednesday, August 4 |
| » Lost to Browns (37-57), 9-8 | Sportsman's Park III (4-3) | 58-41 | |
| » Starters: Mel Parnell vs Blackie Schwamb | Fourth | 2½ out |
| Thursday, August 5 |
| » Defeated Browns (37-58), 8-7 | Sportsman's Park III (5-3) | 59-41 | |
| » Starters: Joe Dobson vs Cliff Fannin | Fourth | 2½ out |
| Friday, August 6 |
| » Lost to White Sox (33-66), 4-3 | Comiskey Park I (2-4) | 59-42 | |
| » Starters: Denny Galehouse vs Bill Wight | Fourth | 2½ out |
| Saturday, August 7 |
| » Lost to White Sox (34-66), 5-1 | Comiskey Park I (2-5) | 59-43 | Lost 2 |
| » Starters: Mickey Harris vs Al Gettel | Fourth | 2½ out |
| Sunday, August 8 |
| » Defeated White Sox (34-67), 8-1 | Comiskey Park I (3-5) | 60-43 | |
| » Starters: Mel Parnell vs Randy Gumpert | Fourth | 2½ out |
| » Lost to White Sox (35-67), 2-1 | Comiskey Park I (3-6) | 60-44 | |
| » Starters: Ellis Kinder vs Joe Haynes | Fourth | 2½ out |
| Monday, August 9 |
| Future Red Sox Bill Campbell is born in Highland Park, MI. Former Red Sox Harry Lord dies in Westbrook, ME at the age of 67 |
| Tuesday, August 10 |
| » Defeated Yankees (59-43), 9-6 | Yankee Stadium (3-4) | 61-44 | |
| » Starters: Jack Kramer vs Ed Lopat | Third | 2 out |
| Wednesday, August 11 |
| » Defeated Yankees (59-44), 5-2 | Yankee Stadium (4-4) | 62-44 | Won 2 |
| » Starters: Denny Galehouse vs Allie Reynolds | Third | 2 out |
| Friday, August 13 |
| » Defeated Senators (43-63), 6-2 | Griffith Stadium (2-4) | 63-44 | Won 3 |
| » Starters: Mel Parnell vs Early Wynn | Third | 1½ out |
| Saturday, August 14 |
| » Defeated Senators (43-64), 4-3 | Griffith Stadium (3-4) | 64-44 | Won 4 |
| » Starters: Joe Dobson vs Mickey Haefner | Second | 1½ out |
| Sunday, August 15 |
| » Lost to Senators (44-64), 5-4 | Griffith Stadium (3-5) | 64-45 | |
| » Starters: Jack Kramer vs Ray Scarborough | Third | 2½ out |
| » Defeated Senators (44-65), 8-7 | Griffith Stadium (4-5) | 65-45 | |
| » Starters: Ellis Kinder vs Walt Masterson | Third | 2½ out |
| Monday, August 16 |
| Former Red Sox Babe Ruth dies in New York, NY at the age of 54. |
| Wednesday, August 18 |
| » Defeated Athletics (67-46), 10-2 | Fenway Park (36-16) | 66-45 | Won 2 |
| » Starters: Carl Scheib vs Denny Galehouse | Second | 3 out |
| Thursday, August 19 |
| » Lost to Athletics (68-46), 10-3 | Fenway Park (36-17) | 66-46 | |
| » Starters: Dick Fowler vs Joe Dobson | Third | 3½ out |
| Friday, August 20 |
| » Defeated Senators (44-69), 5-4 | Fenway Park (37-17) | 67-46 | |
| » Starters: Ray Scarborough vs Mel Parnell | Second | 3 out |
| » Defeated Senators (44-70), 10-4 | Fenway Park (38-17) | 68-46 | Won 2 |
| » Starters: Earl Harrist vs Jack Kramer | Second | 3 out |
| Saturday, August 21 |
| » Defeated Senators (44-71), 10-6 | Fenway Park (39-17) | 69-46 | Won 3 |
| » Starters: Dick Welteroth vs Ellis Kinder | Second | 2 out |
| Sunday, August 22 |
| » Defeated Senators (44-72), 4-1 | Fenway Park (40-17) | 70-46 | Won 4 |
| » Starters: Forrest Thompson vs Mickey Harris | Second | ½ out |
| Tuesday, August 24 |
| » Defeated Indians (70-46), 9-8 | Fenway Park (41-17) | 71-46 | Won 5 |
| » Starters: Satchel Paige vs Joe Dobson | First | -- |
| Wednesday, August 25 |
| » Lost to Indians (71-46), 9-0 | Fenway Park (41-18) | 71-47 | |
| » Starters: Bob Lemon vs Denny Galehouse | Second | ½ out |
| Thursday, August 26 |
| » Defeated Indians (71-47), 8-4 | Fenway Park (42-18) | 72-47 | |
| » Starters: Gene Bearden vs Mel Parnell | First | -- |
| Friday, August 27 |
| » Defeated White Sox (40-79), 10-5 | Fenway Park (43-18) | 73-47 | Won 2 |
| » Starters: Marino Pieretti vs Jack Kramer | First | -- |
| Saturday, August 28 |
| » Defeated White Sox (40-80), 6-2 | Fenway Park (44-18) | 74-47 | Won 3 |
| » Starters: Bill Wight vs Ellis Kinder | First | -- |
| Sunday, August 29 |
| » Defeated Browns (46-73), 10-2 | Fenway Park (45-18) | 75-47 | Won 4 |
| » Starters: Karl Drews vs Joe Dobson | First | -- |
| » Lost to Browns (47-73), 12-4 | Fenway Park (45-19) | 75-48 | |
| » Starters: Ned Garver vs Mickey Harris | First | -- |
| Tuesday, August 31 |
| » Defeated Tigers (59-61), 8-4 | Fenway Park (46-19) | 76-48 | |
| » Starters: Art Houtteman vs Mel Parnell | First | -- |
| Wednesday, September 1 |
| » Defeated Tigers (59-62), 10-1 | Fenway Park (47-19) | 77-48 | Won 2 |
| » Starters: Virgil Trucks vs Jack Kramer | First | -- |
| Friday, September 3 |
| » Defeated Athletics (73-56), 2-0 | Shibe Park (6-3) | 78-48 | Won 3 |
| » Starters: Joe Dobson vs Carl Scheib | First | -- |
| Former Red Sox Bert Husting dies in Milwaukee, WI at the age of 71. |
| Saturday, September 4 |
| » Defeated Athletics (73-57), 5-3 | Shibe Park (7-3) | 79-48 | Won 4 |
| » Starters: Ellis Kinder vs Phil Marchildon | First | -- |
| Sunday, September 5 |
| » Defeated Athletics (73-58), 4-3 | Shibe Park (8-3) | 80-48 | Won 5 |
| » Starters: Denny Galehouse vs Dick Fowler | First | -- |
| Monday, September 6 |
| » Defeated Senators (49-82), 14-6 | Griffith Stadium (5-5) | 81-48 | Won 6 |
| » Starters: Mel Parnell vs Mickey Haefner | First | -- |
| » Defeated Senators (49-83), 2-1 | Griffith Stadium (6-5) | 82-48 | Won 7 |
| » Starters: Jack Kramer vs Walt Masterson | First | -- |
| Wednesday, September 8 |
| » Defeated Yankees (81-51), 10-6 | Fenway Park (48-19) | 83-48 | Won 8 |
| » Starters: Spec Shea vs Joe Dobson | First | -- |
| Thursday, September 9 |
| » Defeated Yankees (81-52), 9-4 | Fenway Park (49-19) | 84-48 | Won 9 |
| » Starters: Bob Porterfield vs Ellis Kinder | First | -- |
| Friday, September 10 |
| » Lost to Yankees (82-52), 11-6 | Fenway Park (49-20) | 84-49 | |
| » Starters: Vic Raschi vs Jack Kramer | First | -- |
| Saturday, September 11 |
| » Defeated Athletics (78-60), 9-1 | Fenway Park (50-20) | 85-49 | |
| » Starters: Bill McCahan vs Denny Galehouse | First | -- |
| » Defeated Athletics (78-61), 2-1 | Fenway Park (51-20) | 86-49 | Won 2 |
| » Starters: Joe Coleman vs Mel Parnell | First | -- |
| Future Red Sox Jeff Newman is born in Fort Worth, TX. |
| Sunday, September 12 |
| » Lost to Athletics (79-61), 10-4 | Fenway Park (51-21) | 86-50 | |
| » Starters: Carl Scheib vs Joe Dobson | First | -- |
| Tuesday, September 14 |
| » Defeated White Sox (45-92), 4-1 | Comiskey Park I (4-6) | 87-50 | |
| » Starters: Ellis Kinder vs Bill Wight | First | -- |
| Wednesday, September 15 |
| » Lost to White Sox (46-92), 17-10 | Comiskey Park I (4-7) | 87-51 | |
| » Starters: Jack Kramer vs Al Gettel | First | -- |
| » Major-league debuts: Tom Wright (Red Sox) |
| Thursday, September 16 |
| » Lost to Browns (55-82), 3-1 | Sportsman's Park III (5-4) | 87-52 | Lost 2 |
| » Starters: Mel Parnell vs Cliff Fannin | First | -- |
| Friday, September 17 |
| » Defeated Browns (55-83), 9-3 | Sportsman's Park III (6-4) | 88-52 | |
| » Starters: Joe Dobson vs Bill Kennedy | First | -- |
| Saturday, September 18 |
| » Defeated Browns (55-84), 11-6 | Sportsman's Park III (7-4) | 89-52 | Won 2 |
| » Starters: Denny Galehouse vs Ned Garver | First | -- |
| Future Red Sox Ken Brett is born in Brooklyn, NY. |
| Sunday, September 19 |
| » Lost to Tigers (70-70), 4-3 | Tiger Stadium (4-4) | 89-53 | |
| » Starters: Ellis Kinder vs Virgil Trucks | First | -- |
| » Lost to Tigers (71-70), 8-6 | Tiger Stadium (4-5) | 89-54 | Lost 2 |
| » Starters: Jack Kramer vs Art Houtteman | First | -- |
| Monday, September 20 |
| » Defeated Tigers (71-71), 7-2 | Tiger Stadium (5-5) | 90-54 | |
| » Starters: Mickey Harris vs Fred Hutchinson | First | -- |
| Tuesday, September 21 |
| » Defeated Tigers (71-72), 10-2 | Tiger Stadium (6-5) | 91-54 | Won 2 |
| » Starters: Mel Parnell vs Ted Gray | First | -- |
| Wednesday, September 22 |
| » Lost to Indians (91-55), 5-2 | Cleveland Stadium (5-6) | 91-55 | |
| » Starters: Joe Dobson vs Bob Feller | First | -- |
| Friday, September 24 |
| » Lost to Yankees (91-56), 9-6 | Yankee Stadium (4-5) | 91-56 | Lost 2 |
| » Starters: Ellis Kinder vs Vic Raschi | First | -- |
| Saturday, September 25 |
| » Defeated Yankees (91-57), 7-2 | Yankee Stadium (5-5) | 92-56 | |
| » Starters: Jack Kramer vs Allie Reynolds | First | -- |
| » Major-league debuts: Joe Collins (Yankees) |
| Sunday, September 26 |
| » Lost to Yankees (92-57), 6-2 | Yankee Stadium (5-6) | 92-57 | |
| » Starters: Mel Parnell vs Tommy Byrne | Second | 1 out |
| Tuesday, September 28 |
| » Lost to Senators (54-95), 4-2 | Fenway Park (51-22) | 92-58 | Lost 2 |
| » Starters: Ray Scarborough vs Joe Dobson | Second | 2 out |
| Wednesday, September 29 |
| » Defeated Senators (54-96), 5-1 | Fenway Park (52-22) | 93-58 | |
| » Starters: Walt Masterson vs Ellis Kinder | Second | 2 out |
| Thursday, September 30 |
| » Defeated Senators (54-97), 7-3 | Fenway Park (53-22) | 94-58 | Won 2 |
| » Starters: Early Wynn vs Mel Parnell | Second | 1½ out |
| Saturday, October 2 |
| » Defeated Yankees (94-59), 5-1 | Fenway Park (54-22) | 95-58 | Won 3 |
| » Starters: Tommy Byrne vs Jack Kramer | Second | 1 out |
| Sunday, October 3 |
| » Defeated Yankees (94-60), 10-5 | Fenway Park (55-22) | 96-58 | Won 4 |
| » Starters: Bob Porterfield vs Joe Dobson | First | -- |
| Monday, October 4 |
| » Lost to Indians (97-58), 8-3 | Fenway Park (55-23) | 96-59 | |
| » Starters: Gene Bearden vs Denny Galehouse | Second | 1 out |
| Wednesday, November 3 |
| Future Red Sox Rick Kreuger is born in Grand Rapids, MI. |
| Sunday, December 26 |
| Future Red Sox Dave Rader is born in Claremore, OK. |
Game information provided by Retrosheet (www.retrosheet.org) |
