| Saturday, February 14 |
| Former Cardinal Three-Finger Brown dies in Terre Haute, IN at the age of 72. |
| Sunday, February 29 |
| Former Cardinal Rebel Oakes dies in Rocky Springs, LA at the age of 65. |
| Thursday, March 4 |
| Future Cardinal Tom Grieve is born in Pittsfield, MA. |
| Tuesday, March 9 |
| Future Cardinal John Curtis is born in Newton, MA. |
| Wednesday, March 24 |
| Former Cardinal Jimmy Bannon dies in Glen Rock, NJ at the age of 77. |
| Thursday, March 25 |
| Future Cardinal Mike Nagy is born in Bronx, NY. |
| Monday, April 19 |
| » Major-league debuts: Monty Basgall and Ed Fitz Gerald (Pirates) |
| Tuesday, April 20 |
| » Defeated Reds (1-1), 4-0 | Sportsman's Park III (1-0) | 1-0 | |
| » Starters: Howie Fox vs Murry Dickson | First | -- |
| Wednesday, April 21 |
| » Defeated Reds (1-2), 5-2 | Sportsman's Park III (2-0) | 2-0 | Won 2 |
| » Starters: Johnny Vander Meer vs Red Munger | First | -- |
| Thursday, April 22 |
| » Lost to Reds (2-2), 4-3 | Sportsman's Park III (2-1) | 2-1 | |
| » Starters: Ken Raffensberger vs Howie Pollet | First | -- |
| Friday, April 23 |
| » Defeated Cubs (1-3), 1-0 | Wrigley Field (1-0) | 3-1 | |
| » Starters: Harry Brecheen vs Johnny Schmitz | First | -- |
| Saturday, April 24 |
| » Lost to Cubs (2-3), 6-2 | Wrigley Field (1-1) | 3-2 | |
| » Starters: Al Brazle vs Cliff Chambers | First | -- |
| » Major-league debuts: Cliff Chambers (Cubs) Al Papai (Cardinals) |
| Sunday, April 25 |
| » Lost to Cubs (3-3), 3-1 | Wrigley Field (1-2) | 3-3 | Lost 2 |
| » Starters: Murry Dickson vs Russ Meyer | Third | 1½ out |
| Thursday, April 29 |
| » Lost to Reds (6-5), 5-4 | Crosley Field (0-1) | 3-4 | Lost 3 |
| » Starters: Red Munger vs Ken Raffensberger | Sixth | 2½ out |
| » Major-league debuts: Hal Rice (Cardinals) |
| Friday, April 30 |
| » Defeated Reds (6-6), 13-7 | Crosley Field (1-1) | 4-4 | |
| » Starters: Howie Pollet vs Howie Fox | Third | 1½ out |
| Future Cardinal Mike Barlow is born in Stamford, NY. |
| Saturday, May 1 |
| » Defeated Cubs (4-7), 4-0 | Sportsman's Park III (3-1) | 5-4 | Won 2 |
| » Starters: Cliff Chambers vs Harry Brecheen | Third | 1 out |
| Sunday, May 2 |
| » Lost to Cubs (5-7), 13-4 | Sportsman's Park III (3-2) | 5-5 | |
| » Starters: Russ Meyer vs Murry Dickson | Fourth | 2 out |
| Monday, May 3 |
| » Defeated Cubs (5-8), 3-1 | Sportsman's Park III (4-2) | 6-5 | |
| » Starters: Johnny Schmitz vs Jim Hearn | Third | 1½ out |
| Tuesday, May 4 |
| » Defeated Dodgers (7-7), 5-4 | Sportsman's Park III (5-2) | 7-5 | Won 2 |
| » Starters: Ralph Branca vs Red Munger | Third | 1 out |
| Thursday, May 6 |
| » Major-league debuts: Bob Chesnes (Pirates) |
| Friday, May 7 |
| » Defeated Phillies (7-9), 7-4 | Sportsman's Park III (6-2) | 8-5 | Won 3 |
| » Starters: Dutch Leonard vs Howie Pollet | Third | ½ out |
| Saturday, May 8 |
| » Defeated Phillies (7-10), 5-0 | Sportsman's Park III (7-2) | 9-5 | Won 4 |
| » Starters: Blix Donnelly vs Harry Brecheen | Second | 1½ out |
| Future Cardinal Steve Braun is born in Trenton, NJ. |
| Sunday, May 9 |
| » Defeated Braves (8-10), 6-4 | Sportsman's Park III (8-2) | 10-5 | Won 5 |
| » Starters: Warren Spahn vs Murry Dickson | First | -- |
| Monday, May 10 |
| » Lost to Braves (9-10), 6-0 | Sportsman's Park III (8-3) | 10-6 | |
| » Starters: Johnny Sain vs Jim Hearn | First | -- |
| Thursday, May 13 |
| » Lost to Giants (12-7), 5-0 | Sportsman's Park III (8-4) | 10-7 | Lost 2 |
| » Starters: Ray Poat vs Red Munger | Third | 1 out |
| Friday, May 14 |
| » Defeated Pirates (12-9), 2-1 | Sportsman's Park III (9-4) | 11-7 | |
| » Starters: Fritz Ostermueller vs Howie Pollet | Second | ½ out |
| Saturday, May 15 |
| » Defeated Pirates (12-10), 8-3 | Sportsman's Park III (10-4) | 12-7 | Won 2 |
| » Starters: Elmer Riddle vs Harry Brecheen | First | -- |
| Sunday, May 16 |
| » Defeated Pirates (12-11), 6-5 | Sportsman's Park III (11-4) | 13-7 | Won 3 |
| » Starters: Kirby Higbe vs Murry Dickson | First | -- |
| Tuesday, May 18 |
| » Defeated Dodgers (11-13), 4-3 | Ebbets Field (1-0) | 14-7 | Won 4 |
| » Starters: Red Munger vs Ralph Branca | First | -- |
| Wednesday, May 19 |
| » Defeated Dodgers (11-14), 14-7 | Ebbets Field (2-0) | 15-7 | Won 5 |
| » Starters: Al Brazle vs Rex Barney | First | -- |
| Future Cardinal Al Santorini is born in Irvington, NJ. |
| Thursday, May 20 |
| » Defeated Dodgers (11-15), 13-4 | Ebbets Field (3-0) | 16-7 | Won 6 |
| » Starters: Howie Pollet vs Joe Hatten | First | -- |
| Friday, May 21 |
| » Lost to Braves (14-12), 3-1 | Braves Field (0-1) | 16-8 | |
| » Starters: Harry Brecheen vs Warren Spahn | First | -- |
| Saturday, May 22 |
| » Defeated Braves (14-13), 6-4 | Braves Field (1-1) | 17-8 | |
| » Starters: Murry Dickson vs Johnny Sain | First | -- |
| Sunday, May 23 |
| » Defeated Phillies (14-15), 18-3 | Shibe Park (1-0) | 18-8 | Won 2 |
| » Starters: Red Munger vs Blix Donnelly | First | -- |
| » Defeated Phillies (14-16), 4-1 | Shibe Park (2-0) | 19-8 | Won 3 |
| » Starters: Jim Hearn vs Dutch Leonard | First | -- |
| Future Cardinal Reggie Cleveland is born in Swift Current, SK. |
| Monday, May 24 |
| » Lost to Phillies (15-16), 6-2 | Shibe Park (2-1) | 19-9 | |
| » Starters: Al Brazle vs Monk Dubiel | First | -- |
| Wednesday, May 26 |
| » Lost to Giants (17-11), 10-7 | Polo Grounds V (0-1) | 19-10 | Lost 2 |
| » Starters: Howie Pollet vs Dave Koslo | First | -- |
| Thursday, May 27 |
| » Defeated Giants (17-12), 9-6 | Polo Grounds V (1-1) | 20-10 | |
| » Starters: Murry Dickson vs Ray Poat | First | -- |
| Friday, May 28 |
| » Tied Pirates, 1-1 | Forbes Field (0-0) | 20-10 | |
| » Starters: Harry Brecheen vs Fritz Ostermueller | First | -- |
| Saturday, May 29 |
| » Lost to Pirates (17-15), 7-3 | Forbes Field (0-1) | 20-11 | |
| » Starters: Red Munger vs Bob Chesnes | First | -- |
| Sunday, May 30 |
| » Lost to Pirates (18-15), 9-3 | Forbes Field (0-2) | 20-12 | Lost 2 |
| » Starters: Howie Pollet vs Hal Gregg | First | -- |
| » Lost to Pirates (19-15), 7-6 | Forbes Field (0-3) | 20-13 | Lost 3 |
| » Starters: Jim Hearn vs Elmer Singleton | First | -- |
| Monday, May 31 |
| » Lost to Reds (17-21), 4-3 | Crosley Field (1-2) | 20-14 | Lost 4 |
| » Starters: Al Brazle vs Howie Fox | Second | ½ out |
| » Lost to Reds (18-21), 7-0 | Crosley Field (1-3) | 20-15 | Lost 5 |
| » Starters: Murry Dickson vs Ken Raffensberger | Second | ½ out |
| Wednesday, June 2 |
| » Lost to Dodgers (17-20), 5-3 | Sportsman's Park III (11-5) | 20-16 | Lost 6 |
| » Starters: Joe Hatten vs Red Munger | Second | 1½ out |
| Thursday, June 3 |
| » Defeated Dodgers (17-21), 4-1 | Sportsman's Park III (12-5) | 21-16 | |
| » Starters: Preacher Roe vs Harry Brecheen | Second | ½ out |
| Friday, June 4 |
| » Lost to Dodgers (18-21), 1-0 | Sportsman's Park III (12-6) | 21-17 | |
| » Starters: Ralph Branca vs Howie Pollet | Second | 1½ out |
| Saturday, June 5 |
| » Defeated Dodgers (18-22), 9-6 | Sportsman's Park III (13-6) | 22-17 | |
| » Starters: Harry Taylor vs Murry Dickson | Second | ½ out |
| Sunday, June 6 |
| » Defeated Phillies (23-21), 11-1 | Sportsman's Park III (14-6) | 23-17 | Won 2 |
| » Starters: Ken Heintzelman vs Jim Hearn | First | -- |
| » Defeated Phillies (23-22), 2-0 | Sportsman's Park III (15-6) | 24-17 | Won 3 |
| » Starters: Nick Strincevich vs Al Brazle | First | -- |
| Monday, June 7 |
| » Lost to Phillies (24-22), 5-1 | Sportsman's Park III (15-7) | 24-18 | |
| » Starters: Dutch Leonard vs Red Munger | Second | ½ out |
| Tuesday, June 8 |
| » Defeated Phillies (24-23), 7-5 | Sportsman's Park III (16-7) | 25-18 | |
| » Starters: Monk Dubiel vs Harry Brecheen | Second | 1 out |
| Wednesday, June 9 |
| » Lost to Braves (23-19), 11-5 | Sportsman's Park III (16-8) | 25-19 | |
| » Starters: Warren Spahn vs Howie Pollet | Second | ½ out |
| Thursday, June 10 |
| » Lost to Braves (24-19), 10-2 | Sportsman's Park III (16-9) | 25-20 | Lost 2 |
| » Starters: Johnny Sain vs Murry Dickson | Third | ½ out |
| Friday, June 11 |
| » Lost to Braves (25-19), 7-3 | Sportsman's Park III (16-10) | 25-21 | Lost 3 |
| » Starters: Bill Voiselle vs Al Brazle | Third | 1 out |
| Saturday, June 12 |
| » Lost to Giants (26-20), 7-5 | Sportsman's Park III (16-11) | 25-22 | Lost 4 |
| » Starters: Larry Jansen vs Jim Hearn | Third | 1½ out |
| Sunday, June 13 |
| » Lost to Giants (27-20), 8-7 | Sportsman's Park III (16-12) | 25-23 | Lost 5 |
| » Starters: Ray Poat vs Harry Brecheen | Third | 1½ out |
| » Defeated Giants (27-21), 3-2 | Sportsman's Park III (17-12) | 26-23 | |
| » Starters: Dave Koslo vs Red Munger | Third | 1½ out |
| Tuesday, June 15 |
| » Defeated Phillies (26-26), 2-1 | Shibe Park (3-1) | 27-23 | Won 2 |
| » Starters: Al Brazle vs Dutch Leonard | Third | 1½ out |
| Thursday, June 17 |
| » Defeated Phillies (26-27), 4-1 | Shibe Park (4-1) | 28-23 | Won 3 |
| » Starters: Harry Brecheen vs Curt Simmons | Third | 1½ out |
| Friday, June 18 |
| » Defeated Giants (27-25), 12-8 | Polo Grounds V (2-1) | 29-23 | Won 4 |
| » Starters: Howie Pollet vs Andy Hansen | Third | 1½ out |
| Saturday, June 19 |
| » Lost to Giants (28-25), 10-1 | Polo Grounds V (2-2) | 29-24 | |
| » Starters: Red Munger vs Clint Hartung | Third | 2½ out |
| Sunday, June 20 |
| » Defeated Giants (28-26), 7-2 | Polo Grounds V (3-2) | 30-24 | |
| » Starters: Murry Dickson vs Monte Kennedy | Third | 3½ out |
| » Lost to Giants (29-26), 6-4 | Polo Grounds V (3-3) | 30-25 | |
| » Starters: Jim Hearn vs Ray Poat | Third | 3½ out |
| Monday, June 21 |
| » Defeated Braves (34-23), 1-0 | Braves Field (2-1) | 31-25 | |
| » Starters: Al Brazle vs Warren Spahn | Third | 2½ out |
| Tuesday, June 22 |
| » Defeated Braves (34-24), 5-2 | Braves Field (3-1) | 32-25 | Won 2 |
| » Starters: Harry Brecheen vs Bill Voiselle | Third | 1½ out |
| Thursday, June 24 |
| » Defeated Braves (34-25), 11-2 | Braves Field (4-1) | 33-25 | Won 3 |
| » Starters: Howie Pollet vs Johnny Sain | Second | ½ out |
| Friday, June 25 |
| » Lost to Dodgers (27-29), 3-2 | Ebbets Field (3-1) | 33-26 | |
| » Starters: Red Munger vs Ralph Branca | Second | 1½ out |
| Saturday, June 26 |
| » Defeated Dodgers (27-30), 6-3 | Ebbets Field (4-1) | 34-26 | |
| » Starters: Murry Dickson vs Joe Hatten | Second | ½ out |
| Sunday, June 27 |
| » Defeated Dodgers (27-31), 6-4 | Ebbets Field (5-1) | 35-26 | Won 2 |
| » Starters: Al Brazle vs Preacher Roe | Second | ½ out |
| Tuesday, June 29 |
| » Lost to Cubs (26-37), 3-1 | Wrigley Field (1-3) | 35-27 | |
| » Starters: Harry Brecheen vs Johnny Schmitz | Second | ½ out |
| Wednesday, June 30 |
| » Lost to Cubs (27-37), 9-1 | Wrigley Field (1-4) | 35-28 | Lost 2 |
| » Starters: Jim Hearn vs Ralph Hamner | Second | 1½ out |
| Thursday, July 1 |
| » Lost to Cubs (28-37), 4-3 | Wrigley Field (1-5) | 35-29 | Lost 3 |
| » Starters: Murry Dickson vs Bob Chipman | Second | 2½ out |
| Friday, July 2 |
| » Lost to Reds (30-37), 7-3 | Crosley Field (1-4) | 35-30 | Lost 4 |
| » Starters: Howie Pollet vs Johnny Vander Meer | Second | 3½ out |
| Sunday, July 4 |
| » Lost to Reds (31-37), 8-6 | Crosley Field (1-5) | 35-31 | Lost 5 |
| » Starters: Al Brazle vs Ewell Blackwell | Third | 3 out |
| » Defeated Reds (31-38), 8-1 | Crosley Field (2-5) | 36-31 | |
| » Starters: Harry Brecheen vs Ken Raffensberger | Third | 3 out |
| Monday, July 5 |
| » Defeated Cubs (29-40), 6-3 | Sportsman's Park III (18-12) | 37-31 | Won 2 |
| » Starters: Johnny Schmitz vs Murry Dickson | Second | 2 out |
| » Defeated Cubs (29-41), 5-2 | Sportsman's Park III (19-12) | 38-31 | Won 3 |
| » Starters: Ralph Hamner vs Jim Hearn | Second | 2 out |
| Tuesday, July 6 |
| » Lost to Cubs (30-41), 12-10 | Sportsman's Park III (19-13) | 38-32 | |
| » Starters: Russ Meyer vs Red Munger | Second | 3 out |
| Wednesday, July 7 |
| » Lost to Pirates (38-32), 2-1 | Sportsman's Park III (19-14) | 38-33 | Lost 2 |
| » Starters: Bob Chesnes vs Al Brazle | Third | 3 out |
| Thursday, July 8 |
| » Lost to Pirates (39-32), 6-4 | Sportsman's Park III (19-15) | 38-34 | Lost 3 |
| » Starters: Fritz Ostermueller vs Gerry Staley | Third | 4 out |
| Future Cardinal Lerrin LaGrow is born in Phoenix, AZ. |
| Friday, July 9 |
| » Defeated Reds (35-40), 6-4 | Sportsman's Park III (20-15) | 39-34 | |
| » Starters: Herm Wehmeier vs Harry Brecheen | Third | 4 out |
| Saturday, July 10 |
| » Lost to Reds (36-40), 4-3 | Sportsman's Park III (20-16) | 39-35 | |
| » Starters: Johnny Vander Meer vs Murry Dickson | Third | 5 out |
| Sunday, July 11 |
| » Lost to Reds (37-40), 1-0 | Sportsman's Park III (20-17) | 39-36 | Lost 2 |
| » Starters: Ken Raffensberger vs Al Brazle | Third | 6 out |
| Thursday, July 15 |
| » Lost to Phillies (37-42), 3-1 | Sportsman's Park III (20-18) | 39-37 | Lost 3 |
| » Starters: Dutch Leonard vs Harry Brecheen | Third | 7 out |
| Friday, July 16 |
| » Defeated Phillies (37-43), 8-2 | Sportsman's Park III (21-18) | 40-37 | |
| » Starters: Curt Simmons vs Red Munger | Third | 7 out |
| Saturday, July 17 |
| » Lost to Phillies (38-43), 11-10 | Sportsman's Park III (21-19) | 40-38 | |
| » Starters: Blix Donnelly vs Al Brazle | Third | 7 out |
| Sunday, July 18 |
| » Defeated Dodgers (39-38), 6-3 | Sportsman's Park III (22-19) | 41-38 | |
| » Starters: Preacher Roe vs Murry Dickson | Third | 8 out |
| » Lost to Dodgers (40-38), 13-4 | Sportsman's Park III (22-20) | 41-39 | |
| » Starters: Hank Behrman vs Jim Hearn | Third | 8 out |
| Wednesday, July 21 |
| » Defeated Giants (40-40), 8-4 | Sportsman's Park III (23-20) | 42-39 | |
| » Starters: Ray Poat vs Harry Brecheen | Third | 7 out |
| Thursday, July 22 |
| » Lost to Giants (41-40), 6-3 | Sportsman's Park III (23-21) | 42-40 | |
| » Starters: Sheldon Jones vs Murry Dickson | Third | 7 out |
| » Defeated Giants (41-41), 7-6 | Sportsman's Park III (24-21) | 43-40 | |
| » Starters: Monte Kennedy vs Howie Pollet | Third | 7 out |
| Friday, July 23 |
| » Defeated Braves (51-35), 7-5 | Sportsman's Park III (25-21) | 44-40 | Won 2 |
| » Starters: Johnny Sain vs Al Brazle | Third | 6 out |
| Saturday, July 24 |
| » Defeated Braves (51-36), 4-3 | Sportsman's Park III (26-21) | 45-40 | Won 3 |
| » Starters: Bill Voiselle vs Ken Johnson | Third | 5 out |
| Sunday, July 25 |
| » Defeated Braves (51-37), 6-5 | Sportsman's Park III (27-21) | 46-40 | Won 4 |
| » Starters: Warren Spahn vs Gerry Staley | Second | 5 out |
| » Lost to Braves (52-37), 8-6 | Sportsman's Park III (27-22) | 46-41 | |
| » Starters: Vern Bickford vs Harry Brecheen | Second | 5 out |
| Tuesday, July 27 |
| » Lost to Dodgers (46-41), 3-2 | Ebbets Field (5-2) | 46-42 | Lost 2 |
| » Starters: Howie Pollet vs Joe Hatten | Third | 6 out |
| Wednesday, July 28 |
| » Lost to Dodgers (47-41), 12-4 | Ebbets Field (5-3) | 46-43 | Lost 3 |
| » Starters: Ken Johnson vs Preacher Roe | Third | 7 out |
| » Major-league debuts: Bobby Young (Cardinals) |
| Thursday, July 29 |
| » Lost to Dodgers (48-41), 9-6 | Ebbets Field (5-4) | 46-44 | Lost 4 |
| » Starters: Murry Dickson vs Rex Barney | Fourth | 8 out |
| Friday, July 30 |
| » Defeated Braves (55-38), 6-2 | Braves Field (5-1) | 47-44 | |
| » Starters: Harry Brecheen vs Johnny Sain | Fourth | 7 out |
| Saturday, July 31 |
| » Lost to Braves (56-38), 7-6 | Braves Field (5-2) | 47-45 | |
| » Starters: Al Brazle vs Warren Spahn | Fourth | 8 out |
| Sunday, August 1 |
| » Defeated Braves (56-39), 9-6 | Braves Field (6-2) | 48-45 | |
| » Starters: Howie Pollet vs Nels Potter | Fourth | 7 out |
| Monday, August 2 |
| » Defeated Giants (50-44), 21-5 | Polo Grounds V (4-3) | 49-45 | Won 2 |
| » Starters: Murry Dickson vs Ray Poat | Fourth | 6 out |
| » Major-league debuts: Don Mueller (Giants) |
| Wednesday, August 4 |
| » Defeated Giants (50-45), 7-2 | Polo Grounds V (5-3) | 50-45 | Won 3 |
| » Starters: Red Munger vs Sheldon Jones | Second | 4 out |
| » Defeated Giants (50-46), 3-0 | Polo Grounds V (6-3) | 51-45 | Won 4 |
| » Starters: Harry Brecheen vs Larry Jansen | Second | 4 out |
| Friday, August 6 |
| » Defeated Phillies (48-50), 6-2 | Shibe Park (5-1) | 52-45 | Won 5 |
| » Starters: Howie Pollet vs Dutch Leonard | Third | 3½ out |
| Saturday, August 7 |
| » Lost to Phillies (49-50), 6-2 | Shibe Park (5-2) | 52-46 | |
| » Starters: Al Brazle vs Robin Roberts | Second | 4½ out |
| Sunday, August 8 |
| » Defeated Phillies (49-51), 4-1 | Shibe Park (6-2) | 53-46 | |
| » Starters: Murry Dickson vs Curt Simmons | Second | 4 out |
| » Defeated Phillies (49-52), 4-3 | Shibe Park (7-2) | 54-46 | Won 2 |
| » Starters: Red Munger vs Ken Heintzelman | Second | 4 out |
| Monday, August 9 |
| » Defeated Reds (45-59), 6-2 | Crosley Field (3-5) | 55-46 | Won 3 |
| » Starters: Harry Brecheen vs Ken Raffensberger | Second | 3½ out |
| Future Cardinal Bill Campbell is born in Highland Park, MI. |
| Wednesday, August 11 |
| » Defeated Reds (45-60), 9-4 | Crosley Field (4-5) | 56-46 | Won 4 |
| » Starters: Howie Pollet vs Johnny Vander Meer | Third | 3 out |
| Thursday, August 12 |
| » Lost to Pirates (51-47), 3-2 | Forbes Field (0-4) | 56-47 | |
| » Starters: Murry Dickson vs Vic Lombardi | Third | 4 out |
| Friday, August 13 |
| » Lost to Pirates (52-47), 5-4 | Forbes Field (0-5) | 56-48 | Lost 2 |
| » Starters: Red Munger vs Bob Chesnes | Third | 4 out |
| Saturday, August 14 |
| » Defeated Pirates (52-48), 6-3 | Forbes Field (1-5) | 57-48 | |
| » Starters: Harry Brecheen vs Fritz Ostermueller | Third | 4 out |
| Former Cardinal Phil Collins dies in Chicago, IL at the age of 47. |
| Sunday, August 15 |
| » Defeated Pirates (52-49), 8-3 | Forbes Field (2-5) | 58-48 | Won 2 |
| » Starters: Ted Wilks vs Elmer Riddle | Third | 3½ out |
| » Lost to Pirates (53-49), 5-4 | Forbes Field (2-6) | 58-49 | |
| » Starters: Jim Hearn vs Tiny Bonham | Third | 3½ out |
| Monday, August 16 |
| » Defeated Cubs (43-65), 9-7 | Wrigley Field (2-5) | 59-49 | |
| » Starters: Howie Pollet vs Ralph Hamner | Third | 2½ out |
| Tuesday, August 17 |
| » Lost to Cubs (44-65), 4-2 | Wrigley Field (2-6) | 59-50 | |
| » Starters: Red Munger vs Johnny Schmitz | Third | 3½ out |
| Wednesday, August 18 |
| » Defeated Reds (47-64), 4-3 | Sportsman's Park III (28-22) | 60-50 | |
| » Starters: Kent Peterson vs Al Brazle | Third | 2½ out |
| Thursday, August 19 |
| » Defeated Reds (47-65), 4-0 | Sportsman's Park III (29-22) | 61-50 | Won 2 |
| » Starters: Ken Raffensberger vs Harry Brecheen | Third | 2 out |
| Friday, August 20 |
| » Defeated Pirates (56-51), 7-4 | Sportsman's Park III (30-22) | 62-50 | Won 3 |
| » Starters: Fritz Ostermueller vs Ted Wilks | Third | 1½ out |
| Saturday, August 21 |
| » Defeated Pirates (56-52), 9-2 | Sportsman's Park III (31-22) | 63-50 | Won 4 |
| » Starters: Tiny Bonham vs Red Munger | Third | 1 out |
| Sunday, August 22 |
| » Lost to Pirates (57-52), 4-1 | Sportsman's Park III (31-23) | 63-51 | |
| » Starters: Elmer Riddle vs Murry Dickson | Third | 2 out |
| Tuesday, August 24 |
| » Lost to Braves (67-49), 9-3 | Sportsman's Park III (31-24) | 63-52 | Lost 2 |
| » Starters: Johnny Sain vs Harry Brecheen | Second | 3½ out |
| Wednesday, August 25 |
| » Lost to Braves (68-49), 2-0 | Sportsman's Park III (31-25) | 63-53 | Lost 3 |
| » Starters: Warren Spahn vs Howie Pollet | Second | 4½ out |
| Thursday, August 26 |
| » Defeated Giants (60-54), 7-2 | Sportsman's Park III (32-25) | 64-53 | |
| » Starters: Larry Jansen vs Murry Dickson | Second | 2½ out |
| » Defeated Giants (60-55), 7-5 | Sportsman's Park III (33-25) | 65-53 | Won 2 |
| » Starters: Sheldon Jones vs Red Munger | Second | 2½ out |
| Saturday, August 28 |
| » Defeated Giants (60-56), 5-4 | Sportsman's Park III (34-25) | 66-53 | Won 3 |
| » Starters: Monte Kennedy vs Al Brazle | Second | 1½ out |
| » Defeated Giants (60-57), 7-6 | Sportsman's Park III (35-25) | 67-53 | Won 4 |
| » Starters: Ray Poat vs Gerry Staley | Second | 1½ out |
| Sunday, August 29 |
| » Lost to Dodgers (65-52), 12-7 | Sportsman's Park III (35-26) | 67-54 | |
| » Starters: Paul Minner vs Harry Brecheen | Third | 1½ out |
| » Lost to Dodgers (66-52), 6-4 | Sportsman's Park III (35-27) | 67-55 | Lost 2 |
| » Starters: Erv Palica vs Howie Pollet | Third | 1½ out |
| Monday, August 30 |
| » Lost to Dodgers (67-52), 6-5 | Sportsman's Park III (35-28) | 67-56 | Lost 3 |
| » Starters: Carl Erskine vs Murry Dickson | Fourth | 3 out |
| » Lost to Dodgers (68-52), 6-1 | Sportsman's Park III (35-29) | 67-57 | Lost 4 |
| » Starters: Joe Hatten vs Ken Johnson | Fourth | 3 out |
| Tuesday, August 31 |
| » Defeated Phillies (55-68), 5-0 | Sportsman's Park III (36-29) | 68-57 | |
| » Starters: Ken Heintzelman vs Red Munger | Fourth | 2 out |
| Wednesday, September 1 |
| » Defeated Phillies (55-69), 4-2 | Sportsman's Park III (37-29) | 69-57 | Won 2 |
| » Starters: Robin Roberts vs Jim Hearn | Third | 1½ out |
| Saturday, September 4 |
| » Lost to Reds (54-72), 3-1 | Crosley Field (4-6) | 69-58 | |
| » Starters: Harry Brecheen vs Ken Raffensberger | Second | 2½ out |
| Sunday, September 5 |
| » Defeated Reds (54-73), 5-1 | Crosley Field (5-6) | 70-58 | |
| » Starters: Howie Pollet vs Kent Peterson | Second | 2½ out |
| Monday, September 6 |
| » Lost to Pirates (68-58), 2-1 | Forbes Field (2-7) | 70-59 | |
| » Starters: Murry Dickson vs Bob Chesnes | Third | 4½ out |
| » Lost to Pirates (69-58), 4-1 | Forbes Field (2-8) | 70-60 | Lost 2 |
| » Starters: Red Munger vs Vic Lombardi | Third | 4½ out |
| Tuesday, September 7 |
| » Lost to Pirates (70-58), 6-2 | Forbes Field (2-9) | 70-61 | Lost 3 |
| » Starters: Jim Hearn vs Fritz Ostermueller | Fourth | 5 out |
| Wednesday, September 8 |
| » Lost to Cubs (57-75), 4-2 | Sportsman's Park III (37-30) | 70-62 | Lost 4 |
| » Starters: Johnny Schmitz vs Ken Johnson | Fourth | 5½ out |
| Thursday, September 9 |
| » Defeated Cubs (57-76), 4-0 | Sportsman's Park III (38-30) | 71-62 | |
| » Starters: Hank Borowy vs Harry Brecheen | Fourth | 5 out |
| Friday, September 10 |
| » Defeated Reds (55-77), 6-5 | Sportsman's Park III (39-30) | 72-62 | Won 2 |
| » Starters: Ken Raffensberger vs Howie Pollet | Fourth | 4½ out |
| Saturday, September 11 |
| » Lost to Reds (56-77), 3-2 | Sportsman's Park III (39-31) | 72-63 | |
| » Starters: Johnny Vander Meer vs Al Brazle | Fourth | 6 out |
| Sunday, September 12 |
| » Defeated Reds (56-78), 7-6 | Sportsman's Park III (40-31) | 73-63 | |
| » Starters: Kent Peterson vs Murry Dickson | Third | 5½ out |
| Tuesday, September 14 |
| » Defeated Phillies (58-80), 8-0 | Shibe Park (8-2) | 74-63 | Won 2 |
| » Starters: Harry Brecheen vs Ken Heintzelman | Third | 5½ out |
| Wednesday, September 15 |
| » Defeated Phillies (58-81), 2-0 | Shibe Park (9-2) | 75-63 | Won 3 |
| » Starters: Red Munger vs Robin Roberts | Third | 5½ out |
| Friday, September 17 |
| » Defeated Dodgers (76-65), 4-2 | Ebbets Field (6-4) | 76-63 | Won 4 |
| » Starters: Howie Pollet vs Rex Barney | Third | 5½ out |
| Saturday, September 18 |
| » Lost to Dodgers (77-65), 3-2 | Ebbets Field (6-5) | 76-64 | |
| » Starters: Al Brazle vs Carl Erskine | Third | 6½ out |
| Future Cardinal Lee Richard is born in Lafayette, LA. |
| Sunday, September 19 |
| » Defeated Giants (74-67), 4-3 | Polo Grounds V (7-3) | 77-64 | |
| » Starters: Murry Dickson vs Monte Kennedy | Second | 6 out |
| » Defeated Giants (74-68), 3-1 | Polo Grounds V (8-3) | 78-64 | Won 2 |
| » Starters: Harry Brecheen vs Ray Poat | Second | 6 out |
| Tuesday, September 21 |
| » Lost to Braves (85-58), 11-3 | Braves Field (6-3) | 78-65 | |
| » Starters: Red Munger vs Johnny Sain | Third | 8 out |
| » Lost to Braves (86-58), 4-0 | Braves Field (6-4) | 78-66 | Lost 2 |
| » Starters: Howie Pollet vs Vern Bickford | Third | 8 out |
| Future Cardinal Aurelio Lopez is born in Tecamachalco, Mexico. |
| Wednesday, September 22 |
| » Defeated Braves (86-59), 8-2 | Braves Field (7-4) | 79-66 | |
| » Starters: Al Brazle vs Warren Spahn | Second | 7 out |
| Friday, September 24 |
| » Defeated Cubs (60-86), 4-1 | Wrigley Field (3-6) | 80-66 | Won 2 |
| » Starters: Harry Brecheen vs Cliff Chambers | Second | 6½ out |
| » Major-league debuts: Warren Hacker (Cubs) |
| Saturday, September 25 |
| » Lost to Cubs (61-86), 3-2 | Wrigley Field (3-7) | 80-67 | |
| » Starters: Howie Pollet vs Doyle Lade | Third | 6½ out |
| Future Cardinal Ray Busse is born in Daytona Beach, FL. |
| Sunday, September 26 |
| » Defeated Cubs (61-87), 5-2 | Wrigley Field (4-7) | 81-67 | |
| » Starters: Al Brazle vs Bob Rush | Third | 6½ out |
| Wednesday, September 29 |
| » Lost to Pirates (82-68), 2-1 | Sportsman's Park III (40-32) | 81-68 | |
| » Starters: Vic Lombardi vs Murry Dickson | Fourth | 7 out |
| » Major-league debuts: Eddie Kazak (Cardinals) |
| Thursday, September 30 |
| » Defeated Pirates (82-69), 6-1 | Sportsman's Park III (41-32) | 82-68 | |
| » Starters: Bob Chesnes vs Red Munger | Second | 6 out |
| » Defeated Pirates (82-70), 4-1 | Sportsman's Park III (42-32) | 83-68 | Won 2 |
| » Starters: Fritz Ostermueller vs Harry Brecheen | Second | 6 out |
| Friday, October 1 |
| » Defeated Cubs (63-89), 6-4 | Sportsman's Park III (43-32) | 84-68 | Won 3 |
| » Starters: Doyle Lade vs Howie Pollet | Second | 6 out |
| » Major-league debuts: Carmen Mauro (Cubs) |
| Saturday, October 2 |
| » Defeated Cubs (63-90), 9-0 | Sportsman's Park III (44-32) | 85-68 | Won 4 |
| » Starters: Hank Borowy vs Al Brazle | Second | 5½ out |
| Sunday, October 3 |
| » Lost to |
