| Friday, April 16 |
| Former Brown Dick Kauffman dies in Mifflinburg, PA at the age of 60. |
| Monday, April 19 |
| » Major-league debuts: Monty Basgall and Ed Fitz Gerald (Pirates) |
| Tuesday, April 20 |
| » Lost to Indians (1-0), 4-0 | Cleveland Stadium (0-1) | 0-1 | |
| » Starters: Fred Sanford vs Bob Feller | Fourth | 1½ out |
| Wednesday, April 21 |
| » Major-league debuts: Jim Delsing (White Sox) |
| Thursday, April 22 |
| » Major-league debuts: Howie Judson (White Sox) |
| Saturday, April 24 |
| » Defeated White Sox (0-4), 6-4 | Sportsman's Park III (1-0) | 1-1 | |
| » Starters: Joe Haynes vs Cliff Fannin | Fourth | 1½ out |
| Sunday, April 25 |
| » Lost to White Sox (1-4), 4-1 | Sportsman's Park III (1-1) | 1-2 | |
| » Starters: Orval Grove vs Sam Zoldak | Fourth | 2 out |
| » Defeated White Sox (1-5), 7-6 | Sportsman's Park III (2-1) | 2-2 | |
| » Starters: Earl Harrist vs Nels Potter | Fourth | 2 out |
| Monday, April 26 |
| » Defeated Tigers (3-4), 2-1 | Sportsman's Park III (3-1) | 3-2 | Won 2 |
| » Starters: Dizzy Trout vs Fred Sanford | Third | 2 out |
| Tuesday, April 27 |
| » Defeated Tigers (3-5), 9-8 | Sportsman's Park III (4-1) | 4-2 | Won 3 |
| » Starters: Fred Hutchinson vs Bryan Stephens | Second | 1½ out |
| Wednesday, April 28 |
| » Lost to Tigers (4-5), 9-4 | Sportsman's Park III (4-2) | 4-3 | |
| » Starters: Virgil Trucks vs Al Gerheauser | Third | 2 out |
| » Major-league debuts: Ned Garver and Ken Wood (Browns) |
| Thursday, April 29 |
| » Lost to Indians (6-0), 5-2 | Sportsman's Park III (4-3) | 4-4 | Lost 2 |
| » Starters: Bob Lemon vs Cliff Fannin | Fourth | 3 out |
| Saturday, May 1 |
| » Defeated White Sox (3-7), 6-2 | Comiskey Park I (1-0) | 5-4 | |
| » Starters: Fred Sanford vs Orval Grove | Third | 2 out |
| » Major-league debuts: Fred Bradley (White Sox) |
| Sunday, May 2 |
| » Major-league debuts: Joe Tipton (Indians) |
| Tuesday, May 4 |
| » Lost to Yankees (7-5), 6-1 | Yankee Stadium (0-1) | 5-5 | |
| » Starters: Nels Potter vs Spec Shea | Fourth | 1½ out |
| Thursday, May 6 |
| » Lost to Yankees (8-5), 6-5 | Yankee Stadium (0-2) | 5-6 | Lost 2 |
| » Starters: Cliff Fannin vs Allie Reynolds | Fifth | 2½ out |
| Saturday, May 8 |
| » Defeated Red Sox (7-8), 9-4 | Fenway Park (1-0) | 6-6 | |
| » Starters: Fred Sanford vs Mickey Harris | Fourth | 2½ out |
| Sunday, May 9 |
| » Lost to Senators (8-9), 3-1 | Griffith Stadium (0-1) | 6-7 | |
| » Starters: Ned Garver vs Walt Masterson | Fifth | 3½ out |
| Monday, May 10 |
| » Lost to Senators (9-9), 6-2 | Griffith Stadium (0-2) | 6-8 | Lost 2 |
| » Starters: Sam Zoldak vs Early Wynn | Fifth | 4½ out |
| Tuesday, May 11 |
| » Lost to Athletics (13-5), 3-2 | Shibe Park (0-1) | 6-9 | Lost 3 |
| » Starters: Bryan Stephens vs Phil Marchildon | Seventh | 5½ out |
| Wednesday, May 12 |
| » Lost to Athletics (14-5), 8-4 | Shibe Park (0-2) | 6-10 | Lost 4 |
| » Starters: Cliff Fannin vs Dick Fowler | Sixth | 6½ out |
| Friday, May 14 |
| » Defeated Tigers (10-13), 3-0 | Tiger Stadium (1-0) | 7-10 | |
| » Starters: Fred Sanford vs Fred Hutchinson | Sixth | 5½ out |
| Saturday, May 15 |
| » Lost to Tigers (11-13), 4-1 | Tiger Stadium (1-1) | 7-11 | |
| » Starters: Ned Garver vs Dizzy Trout | Seventh | 7 out |
| Sunday, May 16 |
| » Defeated Tigers (11-14), 3-2 | Tiger Stadium (2-1) | 8-11 | |
| » Starters: Sam Zoldak vs Art Houtteman | Sixth | 6½ out |
| Tuesday, May 18 |
| » Defeated Yankees (13-9), 6-5 | Sportsman's Park III (5-3) | 9-11 | Won 2 |
| » Starters: Allie Reynolds vs Cliff Fannin | Sixth | 5 out |
| Wednesday, May 19 |
| » Lost to Yankees (14-9), 8-4 | Sportsman's Park III (5-4) | 9-12 | |
| » Starters: Ed Lopat vs Fred Sanford | Sixth | 6 out |
| Thursday, May 20 |
| » Defeated Senators (11-14), 17-7 | Sportsman's Park III (6-4) | 10-12 | |
| » Starters: Early Wynn vs Bryan Stephens | Fifth | 6 out |
| Friday, May 21 |
| » Defeated Senators (11-15), 4-3 | Sportsman's Park III (7-4) | 11-12 | Won 2 |
| » Starters: Ray Scarborough vs Sam Zoldak | Fifth | 5 out |
| Saturday, May 22 |
| » Defeated Senators (11-16), 4-2 | Sportsman's Park III (8-4) | 12-12 | Won 3 |
| » Starters: Sid Hudson vs Ned Garver | Fourth | 5 out |
| Sunday, May 23 |
| » Lost to Athletics (18-10), 7-3 | Sportsman's Park III (8-5) | 12-13 | |
| » Starters: Dick Fowler vs Bryan Stephens | Fifth | 6 out |
| » Lost to Athletics (19-10), 8-1 | Sportsman's Park III (8-6) | 12-14 | Lost 2 |
| » Starters: Lou Brissie vs Fred Sanford | Fifth | 6 out |
| Tuesday, May 25 |
| » Defeated Red Sox (12-18), 9-4 | Sportsman's Park III (9-6) | 13-14 | |
| » Starters: Ellis Kinder vs Sam Zoldak | Fifth | 6 out |
| Wednesday, May 26 |
| » Lost to Red Sox (13-18), 5-3 | Sportsman's Park III (9-7) | 13-15 | |
| » Starters: Joe Dobson vs Ned Garver | Fifth | 6 out |
| Friday, May 28 |
| » Defeated Tigers (17-18), 5-4 | Sportsman's Park III (10-7) | 14-15 | |
| » Starters: Art Houtteman vs Fred Sanford | Fifth | 7 out |
| Saturday, May 29 |
| » Defeated Tigers (17-19), 6-1 | Sportsman's Park III (11-7) | 15-15 | Won 2 |
| » Starters: Virgil Trucks vs Sam Zoldak | Fourth | 7 out |
| Sunday, May 30 |
| » Lost to Tigers (18-19), 6-4 | Sportsman's Park III (11-8) | 15-16 | |
| » Starters: Hal Newhouser vs Ned Garver | Fifth | 7½ out |
| Monday, May 31 |
| » Lost to Indians (23-10), 8-3 | Cleveland Stadium (0-2) | 15-17 | Lost 2 |
| » Starters: Ray Shore vs Gene Bearden | Fifth | 7½ out |
| » Defeated Indians (23-11), 6-0 | Cleveland Stadium (1-2) | 16-17 | |
| » Starters: Cliff Fannin vs Bob Muncrief | Fifth | 7½ out |
| Wednesday, June 2 |
| » Defeated Red Sox (15-24), 3-1 | Fenway Park (2-0) | 17-17 | Won 2 |
| » Starters: Fred Sanford vs Mel Parnell | Fourth | 5½ out |
| Thursday, June 3 |
| » Lost to Red Sox (16-24), 3-2 | Fenway Park (2-1) | 17-18 | |
| » Starters: Ned Garver vs Jack Kramer | Fifth | 6 out |
| Friday, June 4 |
| » Lost to Red Sox (17-24), 10-4 | Fenway Park (2-2) | 17-19 | Lost 2 |
| » Starters: Bryan Stephens vs Joe Dobson | Sixth | 7½ out |
| » Lost to Red Sox (18-24), 7-2 | Fenway Park (2-3) | 17-20 | Lost 3 |
| » Starters: Sam Zoldak vs Denny Galehouse | Sixth | 7½ out |
| Saturday, June 5 |
| » Lost to Yankees (24-17), 7-1 | Yankee Stadium (0-3) | 17-21 | Lost 4 |
| » Starters: Cliff Fannin vs Red Embree | Fifth | 8½ out |
| Sunday, June 6 |
| » Lost to Yankees (25-17), 4-3 | Yankee Stadium (0-4) | 17-22 | Lost 5 |
| » Starters: Sam Zoldak vs Allie Reynolds | Fifth | 10½ out |
| » Lost to Yankees (26-17), 3-0 | Yankee Stadium (0-5) | 17-23 | Lost 6 |
| » Starters: Fred Sanford vs Vic Raschi | Fifth | 10½ out |
| Monday, June 7 |
| » Defeated Yankees (26-18), 5-3 | Yankee Stadium (1-5) | 18-23 | |
| » Starters: Ned Garver vs Spec Shea | Sixth | 10 out |
| Tuesday, June 8 |
| » Lost to Senators (22-24), 6-5 | Griffith Stadium (0-3) | 18-24 | |
| » Starters: Bryan Stephens vs Sid Hudson | Sixth | 11 out |
| Wednesday, June 9 |
| » Lost to Senators (23-24), 5-2 | Griffith Stadium (0-4) | 18-25 | Lost 2 |
| » Starters: Cliff Fannin vs Early Wynn | Seventh | 11½ out |
| Thursday, June 10 |
| » Lost to Senators (24-24), 5-4 | Griffith Stadium (0-5) | 18-26 | Lost 3 |
| » Starters: Fred Sanford vs Mickey Haefner | Seventh | 11½ out |
| Friday, June 11 |
| » Lost to Athletics (29-19), 6-5 | Shibe Park (0-3) | 18-27 | Lost 4 |
| » Starters: Sam Zoldak vs Phil Marchildon | Seventh | 12½ out |
| Saturday, June 12 |
| » Lost to Athletics (30-19), 3-2 | Shibe Park (0-4) | 18-28 | Lost 5 |
| » Starters: Ned Garver vs Dick Fowler | Seventh | 14 out |
| Former Brown Rasty Wright dies in Columbus, OH at the age of 53. |
| Sunday, June 13 |
| » Defeated Athletics (30-20), 7-5 | Shibe Park (1-4) | 19-28 | |
| » Starters: Ray Shore vs Lou Brissie | Seventh | 13½ out |
| » Lost to Athletics (31-20), 3-1 | Shibe Park (1-5) | 19-29 | |
| » Starters: Bryan Stephens vs Carl Scheib | Seventh | 13½ out |
| Wednesday, June 16 |
| » Defeated Senators (24-29), 6-5 | Sportsman's Park III (12-8) | 20-29 | |
| » Starters: Mickey Haefner vs Fred Sanford | Seventh | 12 out |
| » Major-league debuts: Len Okrie (Senators) |
| Friday, June 18 |
| » Defeated Yankees (29-23), 2-1 | Sportsman's Park III (13-8) | 21-29 | Won 2 |
| » Starters: Spec Shea vs Cliff Fannin | Seventh | 10½ out |
| Saturday, June 19 |
| » Lost to Yankees (30-23), 10-5 | Sportsman's Park III (13-9) | 21-30 | |
| » Starters: Ed Lopat vs Ned Garver | Seventh | 11½ out |
| Sunday, June 20 |
| » Lost to Yankees (31-23), 4-2 | Sportsman's Park III (13-10) | 21-31 | Lost 2 |
| » Starters: Vic Raschi vs Fred Sanford | Seventh | 13½ out |
| » Lost to Yankees (32-23), 6-2 | Sportsman's Park III (13-11) | 21-32 | Lost 3 |
| » Starters: Red Embree vs Bryan Stephens | Seventh | 13½ out |
| Monday, June 21 |
| » Defeated Athletics (33-26), 9-8 | Sportsman's Park III (14-11) | 22-32 | |
| » Starters: Lou Brissie vs Bill Kennedy | Seventh | 12½ out |
| Tuesday, June 22 |
| » Lost to Athletics (34-26), 7-6 | Sportsman's Park III (14-12) | 22-33 | |
| » Starters: Carl Scheib vs Ned Garver | Seventh | 13½ out |
| Wednesday, June 23 |
| » Lost to Athletics (35-26), 12-1 | Sportsman's Park III (14-13) | 22-34 | Lost 2 |
| » Starters: Dick Fowler vs Cliff Fannin | Seventh | 13½ out |
| Thursday, June 24 |
| » Lost to Athletics (36-26), 6-5 | Sportsman's Park III (14-14) | 22-35 | Lost 3 |
| » Starters: Phil Marchildon vs Fred Sanford | Seventh | 13½ out |
| Friday, June 25 |
| » Defeated Red Sox (29-28), 9-6 | Sportsman's Park III (15-14) | 23-35 | |
| » Starters: Mel Parnell vs Bryan Stephens | Seventh | 12½ out |
| Sunday, June 27 |
| » Lost to Red Sox (30-28), 2-0 | Sportsman's Park III (15-15) | 23-36 | |
| » Starters: Joe Dobson vs Bill Kennedy | Seventh | 14 out |
| » Lost to Red Sox (31-28), 6-3 | Sportsman's Park III (15-16) | 23-37 | Lost 2 |
| » Starters: Dave Ferriss vs Ned Garver | Seventh | 14 out |
| Tuesday, June 29 |
| » Lost to White Sox (19-39), 4-1 | Sportsman's Park III (15-17) | 23-38 | Lost 3 |
| » Starters: Bill Wight vs Cliff Fannin | Seventh | 15 out |
| Wednesday, June 30 |
| » Defeated White Sox (19-40), 2-1 | Sportsman's Park III (16-17) | 24-38 | |
| » Starters: Al Gettel vs Fred Sanford | Seventh | 15 out |
| Thursday, July 1 |
| » Defeated White Sox (19-41), 8-5 | Sportsman's Park III (17-17) | 25-38 | Won 2 |
| » Starters: Howie Judson vs Bryan Stephens | Seventh | 14 out |
| Friday, July 2 |
| » Lost to Indians (40-24), 8-6 | Sportsman's Park III (17-18) | 25-39 | |
| » Starters: Don Black vs Bill Kennedy | Seventh | 15 out |
| Saturday, July 3 |
| » Lost to Indians (41-24), 8-2 | Sportsman's Park III (17-19) | 25-40 | Lost 2 |
| » Starters: Bob Feller vs Ned Garver | Seventh | 16 out |
| Monday, July 5 |
| » Lost to White Sox (22-43), 3-2 | Comiskey Park I (1-1) | 25-41 | Lost 3 |
| » Starters: Fred Sanford vs Frank Papish | Seventh | 17 out |
| » Lost to White Sox (23-43), 5-4 | Comiskey Park I (1-2) | 25-42 | Lost 4 |
| » Starters: Cliff Fannin vs Glen Moulder | Seventh | 17 out |
| Tuesday, July 6 |
| » Defeated White Sox (23-44), 7-6 | Comiskey Park I (2-2) | 26-42 | |
| » Starters: Bryan Stephens vs Marino Pieretti | Seventh | 16 out |
| Wednesday, July 7 |
| » Lost to Tigers (35-37), 6-0 | Tiger Stadium (2-2) | 26-43 | |
| » Starters: Bill Kennedy vs Hal Newhouser | Seventh | 17 out |
| Thursday, July 8 |
| » Lost to Tigers (36-37), 12-2 | Tiger Stadium (2-3) | 26-44 | Lost 2 |
| » Starters: Frank Biscan vs Virgil Trucks | Seventh | 18 out |
| Friday, July 9 |
| » Defeated Indians (44-27), 5-3 | Cleveland Stadium (2-2) | 27-44 | |
| » Starters: Fred Sanford vs Bob Lemon | Seventh | 17 out |
| Sunday, July 11 |
| » Defeated Indians (44-28), 3-2 | Cleveland Stadium (3-2) | 28-44 | Won 2 |
| » Starters: Cliff Fannin vs Bob Feller | Seventh | 17 out |
| » Lost to Indians (45-28), 5-0 | Cleveland Stadium (3-3) | 28-45 | |
| » Starters: Ray Shore vs Bob Lemon | Seventh | 17 out |
| Thursday, July 15 |
| » Lost to Yankees (45-32), 4-2 | Yankee Stadium (1-6) | 28-46 | Lost 2 |
| » Starters: Fred Sanford vs Frank Hiller | Seventh | 18½ out |
| Friday, July 16 |
| » Defeated Yankees (45-33), 10-4 | Yankee Stadium (2-6) | 29-46 | |
| » Starters: Cliff Fannin vs Allie Reynolds | Seventh | 17½ out |
| Saturday, July 17 |
| » Lost to Yankees (46-33), 4-0 | Yankee Stadium (2-7) | 29-47 | |
| » Starters: Frank Biscan vs Ed Lopat | Seventh | 17½ out |
| Sunday, July 18 |
| » Lost to Red Sox (43-36), 12-5 | Fenway Park (2-4) | 29-48 | Lost 2 |
| » Starters: Bill Kennedy vs Dave Ferriss | Seventh | 19½ out |
| » Lost to Red Sox (44-36), 7-6 | Fenway Park (2-5) | 29-49 | Lost 3 |
| » Starters: Ray Shore vs Mickey Harris | Seventh | 19½ out |
| Monday, July 19 |
| » Lost to Red Sox (45-36), 4-1 | Fenway Park (2-6) | 29-50 | Lost 4 |
| » Starters: Fred Sanford vs Mel Parnell | Seventh | 20½ out |
| Tuesday, July 20 |
| » Lost to Red Sox (46-36), 8-3 | Fenway Park (2-7) | 29-51 | Lost 5 |
| » Starters: Bill Kennedy vs Jack Kramer | Seventh | 20½ out |
| Wednesday, July 21 |
| » Defeated Athletics (53-37), 17-5 | Shibe Park (2-5) | 30-51 | |
| » Starters: Cliff Fannin vs Joe Coleman | Sixth | 20 out |
| Thursday, July 22 |
| » Lost to Athletics (54-37), 8-7 | Shibe Park (2-6) | 30-52 | |
| » Starters: Frank Biscan vs Bill McCahan | Seventh | 20 out |
| Saturday, July 24 |
| » Defeated Senators (38-49), 13-2 | Griffith Stadium (1-5) | 31-52 | |
| » Starters: Bill Kennedy vs Early Wynn | Seventh | 19½ out |
| Sunday, July 25 |
| » Lost to Senators (39-49), 5-1 | Griffith Stadium (1-6) | 31-53 | |
| » Starters: Fred Sanford vs Ray Scarborough | Seventh | 19½ out |
| » Defeated Senators (39-50), 6-4 | Griffith Stadium (2-6) | 32-53 | |
| » Starters: Blackie Schwamb vs Earl Harrist | Seventh | 19½ out |
| » Major-league debuts: Blackie Schwamb (Browns) |
| Tuesday, July 27 |
| » Defeated Yankees (52-38), 4-0 | Sportsman's Park III (18-19) | 33-53 | Won 2 |
| » Starters: Tommy Byrne vs Cliff Fannin | Seventh | 19½ out |
| » Major-league debuts: Hank Arft (Browns) |
| Wednesday, July 28 |
| » Lost to Yankees (53-38), 4-0 | Sportsman's Park III (18-20) | 33-54 | |
| » Starters: Spec Shea vs Ned Garver | Seventh | 19½ out |
| Friday, July 30 |
| » Lost to Senators (40-52), 3-2 | Sportsman's Park III (18-21) | 33-55 | Lost 2 |
| » Starters: Ray Scarborough vs Fred Sanford | Seventh | 21 out |
| Saturday, July 31 |
| » Defeated Senators (40-53), 10-8 | Sportsman's Park III (19-21) | 34-55 | |
| » Starters: Walt Masterson vs Blackie Schwamb | Seventh | 20 out |
| Sunday, August 1 |
| » Defeated Senators (40-54), 8-5 | Sportsman's Park III (20-21) | 35-55 | Won 2 |
| » Starters: Early Wynn vs Cliff Fannin | Seventh | 20 out |
| » Lost to Senators (41-54), 4-3 | Sportsman's Park III (20-22) | 35-56 | |
| » Starters: Earl Harrist vs Ned Garver | Seventh | 20 out |
| Monday, August 2 |
| » Defeated Senators (41-55), 7-5 | Sportsman's Park III (21-22) | 36-56 | |
| » Starters: Sid Hudson vs Bill Kennedy | Seventh | 19½ out |
| Tuesday, August 3 |
| » Lost to Red Sox (58-40), 15-8 | Sportsman's Park III (21-23) | 36-57 | |
| » Starters: Jack Kramer vs Fred Sanford | Seventh | 19½ out |
| Wednesday, August 4 |
| » Defeated Red Sox (58-41), 9-8 | Sportsman's Park III (22-23) | 37-57 | |
| » Starters: Mel Parnell vs Blackie Schwamb | Seventh | 19 out |
| Thursday, August 5 |
| » Lost to Red Sox (59-41), 8-7 | Sportsman's Park III (22-24) | 37-58 | |
| » Starters: Joe Dobson vs Cliff Fannin | Seventh | 20 out |
| Friday, August 6 |
| » Defeated Athletics (61-42), 2-1 | Sportsman's Park III (23-24) | 38-58 | |
| » Starters: Phil Marchildon vs Bill Kennedy | Seventh | 20 out |
| Saturday, August 7 |
| » Lost to Athletics (62-42), 7-1 | Sportsman's Park III (23-25) | 38-59 | |
| » Starters: Lou Brissie vs Fred Sanford | Seventh | 20 out |
| Sunday, August 8 |
| » Lost to Athletics (63-42), 7-5 | Sportsman's Park III (23-26) | 38-60 | Lost 2 |
| » Starters: Dick Fowler vs Blackie Schwamb | Seventh | 21½ out |
| Monday, August 9 |
| » Defeated White Sox (35-68), 8-6 | Sportsman's Park III (24-26) | 39-60 | |
| » Starters: Frank Papish vs Ned Garver | Seventh | 21½ out |
| Tuesday, August 10 |
| » Defeated White Sox (35-69), 3-1 | Sportsman's Park III (25-26) | 40-60 | Won 2 |
| » Starters: Bill Wight vs Cliff Fannin | Seventh | 20½ out |
| Wednesday, August 11 |
| » Lost to Indians (62-40), 7-5 | Sportsman's Park III (25-27) | 40-61 | |
| » Starters: Bob Lemon vs Bryan Stephens | Seventh | 21 out |
| » Defeated Indians (62-41), 12-4 | Sportsman's Park III (26-27) | 41-61 | |
| » Starters: Bob Muncrief vs Bill Kennedy | Seventh | 21 out |
| Thursday, August 12 |
| » Defeated Indians (62-42), 8-4 | Sportsman's Park III (27-27) | 42-61 | Won 2 |
| » Starters: Sam Zoldak vs Joe Ostrowski | Seventh | 21 out |
| » Lost to Indians (63-42), 26-3 | Sportsman's Park III (27-28) | 42-62 | |
| » Starters: Gene Bearden vs Fred Sanford | Seventh | 21 out |
| Friday, August 13 |
| » Defeated Tigers (50-55), 4-1 | Sportsman's Park III (28-28) | 43-62 | |
| » Starters: Hal Newhouser vs Ned Garver | Sixth | 20½ out |
| Saturday, August 14 |
| » Lost to Tigers (51-55), 10-3 | Sportsman's Park III (28-29) | 43-63 | |
| » Starters: Billy Pierce vs Fred Sanford | Sixth | 21½ out |
| Sunday, August 15 |
| » Lost to Tigers (52-55), 3-1 | Sportsman's Park III (28-30) | 43-64 | Lost 2 |
| » Starters: Fred Hutchinson vs Cliff Fannin | Seventh | 23 out |
| Tuesday, August 17 |
| » Lost to Indians (68-42), 8-0 | Cleveland Stadium (3-4) | 43-65 | Lost 3 |
| » Starters: Bill Kennedy vs Gene Bearden | Seventh | 24 out |
| Wednesday, August 18 |
| » Lost to Indians (69-42), 3-0 | Cleveland Stadium (3-5) | 43-66 | Lost 4 |
| » Starters: Joe Ostrowski vs Sam Zoldak | Seventh | 25 out |
| Friday, August 20 |
| » Defeated Tigers (53-56), 5-4 | Tiger Stadium (3-3) | 44-66 | |
| » Starters: Ned Garver vs Art Houtteman | Sixth | 25 out |
| Saturday, August 21 |
| » Lost to Tigers (54-56), 6-5 | Tiger Stadium (3-4) | 44-67 | |
| » Starters: Cliff Fannin vs Fred Hutchinson | Sixth | 25 out |
| Sunday, August 22 |
| » Defeated Tigers (54-57), 10-1 | Tiger Stadium (4-4) | 45-67 | |
| » Starters: Fred Sanford vs Hal Newhouser | Sixth | 23½ out |
| Tuesday, August 24 |
| » Defeated Senators (44-73), 6-5 | Griffith Stadium (3-6) | 46-67 | Won 2 |
| » Starters: Bill Kennedy vs Early Wynn | Sixth | 23 out |
| Wednesday, August 25 |
| » Lost to Senators (45-73), 14-6 | Griffith Stadium (3-7) | 46-68 | |
| » Starters: Joe Ostrowski vs Ray Scarborough | Sixth | 23½ out |
| Thursday, August 26 |
| » Lost to Senators (46-73), 8-7 | Griffith Stadium (3-8) | 46-69 | Lost 2 |
| » Starters: Cliff Fannin vs Sid Hudson | Sixth | 24 out |
| Friday, August 27 |
| » Lost to Athletics (70-51), 6-0 | Shibe Park (2-7) | 46-70 | Lost 3 |
| » Starters: Joe Ostrowski vs Dick Fowler | Sixth | 25½ out |
| » Lost to Athletics (71-51), 9-1 | Shibe Park (2-8) | 46-71 | Lost 4 |
| » Starters: Fred Sanford vs Bill McCahan | Sixth | 25½ out |
| Saturday, August 28 |
| » Lost to Athletics (72-51), 5-4 | Shibe Park (2-9) | 46-72 | Lost 5 |
| » Starters: Bill Kennedy vs Lou Brissie | Sixth | 26½ out |
| Sunday, August 29 |
| » Lost to Red Sox (75-47), 10-2 | Fenway Park (2-8) | 46-73 | Lost 6 |
| » Starters: Karl Drews vs Joe Dobson | Sixth | 26½ out |
| » Defeated Red Sox (75-48), 12-4 | Fenway Park (3-8) | 47-73 | |
| » Starters: Ned Garver vs Mickey Harris | Sixth | 26½ out |
| Tuesday, August 31 |
| » Lost to Yankees (75-49), 10-9 | Yankee Stadium (2-8) | 47-74 | |
| » Starters: Cliff Fannin vs Allie Reynolds | Sixth | 27½ out |
| Wednesday, September 1 |
| » Lost to Yankees (76-49), 5-4 | Yankee Stadium (2-9) | 47-75 | Lost 2 |
| » Starters: Fred Sanford vs Vic Raschi | Seventh | 28½ out |
| Friday, September 3 |
| » Lost to Indians (77-50), 7-0 | Sportsman's Park III (28-31) | 47-76 | Lost 3 |
| » Starters: Bob Lemon vs Bill Kennedy | Sixth | 29 out |
| » Defeated Indians (77-51), 4-3 | Sportsman's Park III (29-31) | 48-76 | |
| » Starters: Sam Zoldak vs Joe Ostrowski | Sixth | 29 out |
| » Major-league debuts: Ray Boone (Indians) |
| Saturday, September 4 |
| » Defeated Indians (77-52), 4-3 | Sportsman's Park III (30-31) | 49-76 | Won 2 |
| » Starters: Satchel Paige vs Ned Garver | Sixth | 29 out |
| Monday, September 6 |
| » Lost to Tigers (62-63), 8-1 | Sportsman's Park III (30-32) | 49-77 | |
| » Starters: Ted Gray vs Fred Sanford | Sixth | 30½ out |
| » Defeated Tigers (62-64), 11-10 | Sportsman's Park III (31-32) | 50-77 | |
| » Starters: Billy Pierce vs Cliff Fannin | Sixth | 30½ out |
| Thursday, September 9 |
| » Defeated White Sox (44-87), 5-2 | Comiskey Park I (3-2) | 51-77 | Won 2 |
| » Starters: Bill Kennedy vs Marino Pieretti | Sixth | 30½ out |
| » Defeated White Sox (44-88), 4-2 | Comiskey Park I (4-2) | 52-77 | Won 3 |
| » Starters: Joe Ostrowski vs Bill Wight | Sixth | 30½ out |
| Friday, September 10 |
| » Defeated White Sox (44-89), 10-7 | Comiskey Park I (5-2) | 53-77 | Won 4 |
| » Starters: Ned Garver vs Marv Rotblatt | Sixth | 29½ out |
| Saturday, September 11 |
| » Lost to Indians (82-53), 4-1 | Cleveland Stadium (3-6) | 53-78 | |
| » Starters: Cliff Fannin vs Steve Gromek | Sixth | 31½ out |
| » Lost to Indians (83-53), 9-1 | Cleveland Stadium (3-7) | 53-79 | Lost 2 |
| » Starters: Al Gerheauser vs Bob Lemon | Sixth | 31½ out |
| Sunday, September 12 |
| » Lost to Indians (84-53), 6-4 | Cleveland Stadium (3-8) | 53-80 | Lost 3 |
| » Starters: Karl Drews vs Satchel Paige | Sixth | 31½ out |
| » Tied Indians, 3-3 | Cleveland Stadium (3-8) | 53-80 | |
| » Starters: Blackie Schwamb vs Bob Feller | Sixth | 31½ out |
| Monday, September 13 |
| » Defeated Indians (84-54), 3-2 | Cleveland Stadium (4-8) | 54-80 | |
| » Starters: Bill Kennedy vs Don Black | Sixth | 31 out |
| Tuesday, September 14 |
| » Lost to Athletics (80-61), 12-2 | Sportsman's Park III (31-33) | 54-81 | |
| » Starters: Lou Brissie vs Joe Ostrowski | Sixth | 32 out |
| Wednesday, September 15 |
| » Lost to Athletics (81-61), 8-7 | Sportsman's Park III (31-34) | 54-82 | Lost 2 |
| » Starters: Dick Fowler vs Frank Biscan | Sixth | 32 out |
| Thursday, September 16 |
| » Defeated Red Sox (87-52), 3-1 | Sportsman's Park III (32-34) | 55-82 | |
| » Starters: Mel Parnell vs Cliff Fannin | Sixth | 31 out |
| Friday, September 17 |
| » Lost to Red Sox (88-52), 9-3 | Sportsman's Park III (32-35) | 55-83 | |
| » Starters: Joe Dobson vs Bill Kennedy | Sixth | 32 out |
| Saturday, September 18 |
| » Lost to Red Sox (89-52), 11-6 | Sportsman's Park III (32-36) | 55-84 | Lost 2 |
| » Starters: Denny Galehouse vs Ned Garver | Sixth | 33 out |
| Sunday, September 19 |
| » Defeated Yankees (87-55), 8-6 | Sportsman's Park III (33-36) | 56-84 | |
| » Starters: Bob Porterfield vs Fred Sanford | Sixth | 32 out |
| » Lost to Yankees (88-55), 9-6 | Sportsman's Park III (33-37) | 56-85 | |
| » Starters: Vic Raschi vs Joe Ostrowski | Sixth | 32 out |
| Monday, September 20 |
| » Lost to Yankees (89-55), 8-7 | Sportsman's Park III (33-38) | 56-86 | Lost 2 |
| » Starters: Allie Reynolds vs Bill Kennedy | Sixth | 33 out |
| Wednesday, September 22 |
| » Lost to Senators (52-95), 5-4 | Sportsman's Park III (33-39) | 56-87 | Lost 3 |
| » Starters: Sid Hudson vs Cliff Fannin | Fifth | 33½ out |
| Thursday, September 23 |
| » Lost to Senators (53-95), 9-8 | Sportsman's Park III (33-40) | 56-88 | Lost 4 |
| » Starters: Ray Scarborough vs Fred Sanford | Fifth | 34 out |
| Friday, September 24 |
| » Lost to White Sox (48-97), 4-3 | Sportsman's Park III (33-41) | 56-89 | Lost 5 |
| » Starters: Al Gettel vs Ned Garver | Fourth | 34 out |
| Saturday, September 25 |
| » Defeated White Sox (48-98), 7-2 | Sportsman's Park III (34-41) | 57-89 | |
| » Starters: Joe Haynes vs Bill Kennedy | Fifth | 34 out |
| Sunday, September 26 |
| » Lost to White Sox (49-98), 3-0 | Sportsman's Park III (34-42) | 57-90 | |
| » Starters: Randy Gumpert vs Cliff Fannin | Fifth | 35 out |
| Tuesday, September 28 |
| » Defeated Tigers (74-75), 5-3 | Tiger Stadium (5-4) | 58-90 | |
| » Starters: Fred Sanford vs Fred Hutchinson | Fifth | 35 out |
| Wednesday, September 29 |
| » Lost to Tigers (75-75), 4-0 | Tiger Stadium (5-5) | 58-91 | |
| » Starters: Ned Garver vs Hal Newhouser | Fifth | 36 out |
| Thursday, September 30 |
| » Lost to Tigers (76-75), 7-2 | Tiger Stadium (5-6) | 58-92 | Lost 2 |
| » Starters: Joe Ostrowski vs Ted Gray | Fifth | 36½ out |
| Friday, October 1 |
| » Defeated White Sox (49-101), 4-0 | Comiskey Park I (6-2) | 59-92 | |
| » Starters: Cliff Fannin vs Marv Rotblatt | Fifth | 36 out |
| » Lost to White Sox (50-101), 3-2 | Comiskey Park I (6-3) | 59-93 | |
| » Starters: Bill Kennedy vs Al Gettel | Fifth | 36 out |
| Sunday, October 3 |
| » Lost to White Sox (51-101), 10-5 | Comiskey Park I (6-4) | 59-94 | Lost 2 |
| » Starters: Fred Sanford vs Bill Wight | Fifth | 36½ out |
| » Tied White Sox, 2-2 | Comiskey Park I (6-4) | 59-94 | |
| » Starters: Ned Garver vs Randy Gumpert | Fifth | 36½ out |
Game information provided by Retrosheet (www.retrosheet.org) |
