| Wednesday, January 29 |
| Former Red Sox Del Gainer dies in Elkins, WV at the age of 61. |
| Monday, February 10 |
| Former Red Sox George Whiteman dies in Houston, TX at the age of 65. |
| Wednesday, April 2 |
| Former Red Sox Charlie Jones dies in Two Harbors, MN at the age of 71. |
| Monday, April 14 |
| Future Red Sox Joe Lahoud is born in Danbury, CT. |
| Tuesday, April 15 |
| » Defeated Senators (0-1), 7-6 | Fenway Park (1-0) | 1-0 | |
| » Starters: Early Wynn vs Tex Hughson | First | -- |
| » Major-league debuts: Harry Dorish and Sam Mele (Red Sox) |
| Thursday, April 17 |
| » Defeated Senators (0-2), 4-1 | Fenway Park (2-0) | 2-0 | Won 2 |
| » Starters: Mickey Haefner vs Joe Dobson | First | -- |
| Friday, April 18 |
| » Defeated Athletics (1-2), 9-3 | Shibe Park (1-0) | 3-0 | Won 3 |
| » Starters: Dave Ferriss vs Bob Savage | First | -- |
| Saturday, April 19 |
| » Defeated Athletics (1-3), 4-2 | Shibe Park (2-0) | 4-0 | Won 4 |
| » Starters: Tex Hughson vs Joe Coleman | First | -- |
| » Major-league debuts: Billy Goodman (Red Sox) |
| Sunday, April 20 |
| » Lost to Senators (2-3), 3-1 | Griffith Stadium (0-1) | 4-1 | |
| » Starters: Mel Parnell vs Walt Masterson | Second | 1½ out |
| » Major-league debuts: Mel Parnell (Red Sox) |
| Tuesday, April 22 |
| » Lost to Yankees (5-2), 5-4 | Yankee Stadium (0-1) | 4-2 | Lost 2 |
| » Starters: Joe Dobson vs Bill Bevens | Third | 1½ out |
| Wednesday, April 23 |
| » Lost to Yankees (6-2), 3-0 | Yankee Stadium (0-2) | 4-3 | Lost 3 |
| » Starters: Dave Ferriss vs Allie Reynolds | Fourth | 1½ out |
| Thursday, April 24 |
| » Defeated Yankees (6-3), 1-0 | Yankee Stadium (1-2) | 5-3 | |
| » Starters: Tex Hughson vs Spec Shea | Third | ½ out |
| Friday, April 25 |
| » Lost to Athletics (2-6), 11-7 | Fenway Park (2-1) | 5-4 | |
| » Starters: Phil Marchildon vs Mel Parnell | Fourth | 1 out |
| » Major-league debuts: Al Widmar (Red Sox) |
| Saturday, April 26 |
| » Lost to Athletics (3-6), 5-2 | Fenway Park (2-2) | 5-5 | Lost 2 |
| » Starters: Dick Fowler vs Tommy Fine | Fourth | 1½ out |
| » Major-league debuts: Tommy Fine (Red Sox) |
| Sunday, April 27 |
| » Tied Athletics, 6-6 | Fenway Park (2-2) | 5-5 | |
| » Starters: Joe Coleman vs Dave Ferriss | Fifth | 1½ out |
| Tuesday, April 29 |
| » Lost to Tigers (6-5), 8-3 | Tiger Stadium (0-1) | 5-6 | Lost 3 |
| » Starters: Tex Hughson vs Virgil Trucks | Sixth | 2 out |
| Future Red Sox Tom House is born in Seattle, WA. |
| Wednesday, April 30 |
| » Defeated Tigers (6-6), 7-1 | Tiger Stadium (1-1) | 6-6 | |
| » Starters: Mel Parnell vs Hal Newhouser | Fourth | 1 out |
| Friday, May 2 |
| » Lost to Indians (6-5), 2-0 | Cleveland Stadium (0-1) | 6-7 | |
| » Starters: Dave Ferriss vs Bob Feller | Fifth | 2 out |
| Saturday, May 3 |
| » Lost to Indians (7-5), 9-3 | Cleveland Stadium (0-2) | 6-8 | Lost 2 |
| » Starters: Tex Hughson vs Red Embree | Seventh | 2½ out |
| Sunday, May 4 |
| » Defeated Browns (6-8), 3-2 | Sportsman's Park III (1-0) | 7-8 | |
| » Starters: Joe Dobson vs Nels Potter | Sixth | 2½ out |
| » Defeated Browns (6-9), 8-1 | Sportsman's Park III (2-0) | 8-8 | Won 2 |
| » Starters: Tommy Fine vs Bob Muncrief | Sixth | 2½ out |
| Tuesday, May 6 |
| » Defeated Browns (6-10), 6-5 | Sportsman's Park III (3-0) | 9-8 | Won 3 |
| » Starters: Mel Parnell vs Jack Kramer | Fourth | 1½ out |
| Thursday, May 8 |
| » Defeated White Sox (10-7), 3-0 | Comiskey Park I (1-0) | 10-8 | Won 4 |
| » Starters: Dave Ferriss vs Johnny Rigney | Third | 1½ out |
| Saturday, May 10 |
| » Lost to Yankees (9-8), 9-6 | Fenway Park (2-3) | 10-9 | |
| » Starters: Spec Shea vs Joe Dobson | Sixth | 1 out |
| Sunday, May 11 |
| » Defeated Yankees (9-9), 8-7 | Fenway Park (3-3) | 11-9 | |
| » Starters: Bill Bevens vs Tommy Fine | Third | 1½ out |
| Monday, May 12 |
| » Defeated Yankees (9-10), 4-3 | Fenway Park (4-3) | 12-9 | Won 2 |
| » Starters: Spud Chandler vs Tex Hughson | Second | 1 out |
| Future Red Sox Bob Heise is born in San Antonio, TX. |
| Tuesday, May 13 |
| » Defeated White Sox (11-11), 19-6 | Fenway Park (5-3) | 13-9 | Won 3 |
| » Starters: Johnny Rigney vs Dave Ferriss | Second | 1 out |
| Wednesday, May 14 |
| » Defeated White Sox (11-12), 5-1 | Fenway Park (6-3) | 14-9 | Won 4 |
| » Starters: Orval Grove vs Joe Dobson | Second | 1 out |
| Thursday, May 15 |
| » Lost to Browns (8-15), 2-1 | Fenway Park (6-4) | 14-10 | |
| » Starters: Bob Muncrief vs Tommy Fine | Second | 2 out |
| Friday, May 16 |
| » Defeated Browns (8-16), 12-7 | Fenway Park (7-4) | 15-10 | |
| » Starters: Jack Kramer vs Harry Dorish | Second | 1 out |
| Saturday, May 17 |
| » Lost to Browns (9-16), 4-2 | Fenway Park (7-5) | 15-11 | |
| » Starters: Ellis Kinder vs Mel Parnell | Second | 2 out |
| Monday, May 19 |
| » Lost to Tigers (17-8), 3-2 | Fenway Park (7-6) | 15-12 | Lost 2 |
| » Starters: Fred Hutchinson vs Dave Ferriss | Second | 2 out |
| » Defeated Tigers (17-9), 5-4 | Fenway Park (8-6) | 16-12 | |
| » Starters: Hal White vs Tex Hughson | Second | 2 out |
| Tuesday, May 20 |
| » Defeated Tigers (17-10), 8-3 | Fenway Park (9-6) | 17-12 | Won 2 |
| » Starters: Dizzy Trout vs Joe Dobson | Second | 1 out |
| Friday, May 23 |
| » Lost to Yankees (14-14), 9-0 | Yankee Stadium (1-3) | 17-13 | |
| » Starters: Harry Dorish vs Allie Reynolds | Second | 1½ out |
| Saturday, May 24 |
| » Lost to Yankees (15-14), 5-0 | Yankee Stadium (1-4) | 17-14 | Lost 2 |
| » Starters: Dave Ferriss vs Spud Chandler | Second | 2½ out |
| Sunday, May 25 |
| » Lost to Yankees (16-14), 17-2 | Yankee Stadium (1-5) | 17-15 | Lost 3 |
| » Starters: Tex Hughson vs Bill Bevens | Fourth | 3 out |
| Monday, May 26 |
| » Lost to Yankees (17-14), 9-3 | Yankee Stadium (1-6) | 17-16 | Lost 4 |
| » Starters: Joe Dobson vs Spec Shea | Fourth | 4 out |
| Tuesday, May 27 |
| » Defeated Athletics (15-18), 4-2 | Shibe Park (3-0) | 18-16 | |
| » Starters: Tommy Fine vs Phil Marchildon | Third | 4 out |
| Wednesday, May 28 |
| » Defeated Athletics (15-19), 9-2 | Shibe Park (4-0) | 19-16 | Won 2 |
| » Starters: Dave Ferriss vs Jesse Flores | Third | 3½ out |
| Thursday, May 29 |
| » Lost to Athletics (16-19), 3-2 | Shibe Park (4-1) | 19-17 | |
| » Starters: Harry Dorish vs Bob Savage | Third | 3½ out |
| Friday, May 30 |
| » Lost to Senators (15-18), 13-6 | Griffith Stadium (0-2) | 19-18 | Lost 2 |
| » Starters: Tex Hughson vs Marino Pieretti | Fourth | 4½ out |
| » Lost to Senators (16-18), 5-3 | Griffith Stadium (0-3) | 19-19 | Lost 3 |
| » Starters: Joe Dobson vs Mickey Haefner | Fourth | 4½ out |
| Monday, June 2 |
| » Defeated White Sox (18-23), 6-2 | Comiskey Park I (2-0) | 20-19 | |
| » Starters: Dave Ferriss vs Johnny Rigney | Fourth | 5 out |
| » Lost to White Sox (19-23), 6-5 | Comiskey Park I (2-1) | 20-20 | |
| » Starters: Tommy Fine vs Bob Gillespie | Fourth | 5 out |
| Tuesday, June 3 |
| » Lost to Browns (16-22), 4-3 | Sportsman's Park III (3-1) | 20-21 | Lost 2 |
| » Starters: Tex Hughson vs Ellis Kinder | Fourth | 5 out |
| Wednesday, June 4 |
| » Defeated Browns (16-23), 5-2 | Sportsman's Park III (4-1) | 21-21 | |
| » Starters: Joe Dobson vs Bob Muncrief | Fourth | 4½ out |
| Future Red Sox Doug Griffin is born in South Gate, CA. |
| Sunday, June 8 |
| » Lost to Tigers (26-17), 5-0 | Tiger Stadium (1-2) | 21-22 | |
| » Starters: Dave Ferriss vs Hal Newhouser | Fifth | 5 out |
| Monday, June 9 |
| » Defeated Indians (19-19), 7-5 | Cleveland Stadium (1-2) | 22-22 | |
| » Starters: Tex Hughson vs Don Black | Fourth | 4 out |
| Tuesday, June 10 |
| » Defeated Indians (19-20), 3-2 | Cleveland Stadium (2-2) | 23-22 | Won 2 |
| » Starters: Joe Dobson vs Al Gettel | Fourth | 3 out |
| Wednesday, June 11 |
| » Defeated Indians (19-21), 3-0 | Cleveland Stadium (3-2) | 24-22 | Won 3 |
| » Starters: Mickey Harris vs Red Embree | Third | 2½ out |
| Friday, June 13 |
| » Defeated White Sox (25-28), 5-3 | Fenway Park (10-6) | 25-22 | Won 4 |
| » Starters: Frank Papish vs Dave Ferriss | Third | 2 out |
| Sunday, June 15 |
| » Defeated White Sox (25-29), 7-3 | Fenway Park (11-6) | 26-22 | Won 5 |
| » Starters: Bob Gillespie vs Tex Hughson | Second | 2 out |
| » Defeated White Sox (25-30), 8-4 | Fenway Park (12-6) | 27-22 | Won 6 |
| » Starters: Orval Grove vs Joe Dobson | Second | 2 out |
| Tuesday, June 17 |
| » Defeated Browns (21-30), 6-5 | Fenway Park (13-6) | 28-22 | Won 7 |
| » Starters: Cliff Fannin vs Dave Ferriss | Second | 2 out |
| Wednesday, June 18 |
| » Defeated Browns (21-31), 6-5 | Fenway Park (14-6) | 29-22 | Won 8 |
| » Starters: Ellis Kinder vs Mickey Harris | Second | 1½ out |
| Friday, June 20 |
| » Lost to Indians (24-23), 3-2 | Fenway Park (14-7) | 29-23 | |
| » Starters: Al Gettel vs Tex Hughson | Second | 2 out |
| Saturday, June 21 |
| » Defeated Indians (24-24), 9-1 | Fenway Park (15-7) | 30-23 | |
| » Starters: Bob Feller vs Joe Dobson | Second | 2½ out |
| Sunday, June 22 |
| » Lost to Indians (25-24), 8-2 | Fenway Park (15-8) | 30-24 | |
| » Starters: Mel Harder vs Dave Ferriss | Second | 2 out |
| » Defeated Indians (25-25), 6-3 | Fenway Park (16-8) | 31-24 | |
| » Starters: Red Embree vs Harry Dorish | Second | 2 out |
| Monday, June 23 |
| » Defeated Tigers (27-29), 8-2 | Fenway Park (17-8) | 32-24 | Won 2 |
| » Starters: Virgil Trucks vs Denny Galehouse | Second | 2 out |
| Wednesday, June 25 |
| » Lost to Tigers (28-29), 4-2 | Fenway Park (17-9) | 32-25 | |
| » Starters: Hal Newhouser vs Tex Hughson | Second | 2½ out |
| » Defeated Tigers (28-30), 4-3 | Fenway Park (18-9) | 33-25 | |
| » Starters: Dizzy Trout vs Dave Ferriss | Second | 2½ out |
| Thursday, June 26 |
| » Lost to Senators (27-30), 7-3 | Griffith Stadium (0-4) | 33-26 | |
| » Starters: Joe Dobson vs Bobo Newsom | Second | 2½ out |
| Friday, June 27 |
| » Lost to Senators (28-30), 3-0 | Griffith Stadium (0-5) | 33-27 | Lost 2 |
| » Starters: Harry Dorish vs Mickey Haefner | Second | 3½ out |
| Saturday, June 28 |
| » Defeated Senators (28-31), 8-0 | Griffith Stadium (1-5) | 34-27 | |
| » Starters: Denny Galehouse vs Sid Hudson | Second | 3½ out |
| Sunday, June 29 |
| » Lost to Athletics (32-31), 3-2 | Shibe Park (4-2) | 34-28 | |
| » Starters: Dave Ferriss vs Phil Marchildon | Second | 4½ out |
| » Lost to Athletics (33-31), 6-5 | Shibe Park (4-3) | 34-29 | Lost 2 |
| » Starters: Bill Zuber vs Dick Fowler | Second | 4½ out |
| Monday, June 30 |
| » Lost to Yankees (41-26), 3-1 | Fenway Park (18-10) | 34-30 | Lost 3 |
| » Starters: Spec Shea vs Joe Dobson | Second | 5½ out |
| Wednesday, July 2 |
| » Lost to Athletics (34-32), 7-6 | Fenway Park (18-11) | 34-31 | Lost 4 |
| » Starters: Carl Scheib vs Denny Galehouse | Second | 6½ out |
| Thursday, July 3 |
| » Lost to Athletics (35-32), 8-4 | Fenway Park (18-12) | 34-32 | Lost 5 |
| » Starters: Phil Marchildon vs Harry Dorish | Fourth | 7 out |
| Friday, July 4 |
| » Lost to Athletics (36-32), 8-6 | Fenway Park (18-13) | 34-33 | Lost 6 |
| » Starters: Dick Fowler vs Dave Ferriss | Fourth | 8 out |
| » Defeated Athletics (36-33), 4-0 | Fenway Park (19-13) | 35-33 | |
| » Starters: Jesse Flores vs Tex Hughson | Fourth | 8 out |
| Saturday, July 5 |
| » Defeated Senators (30-36), 7-6 | Fenway Park (20-13) | 36-33 | Won 2 |
| » Starters: Sid Hudson vs Joe Dobson | Second | 8 out |
| Sunday, July 6 |
| » Defeated Senators (30-37), 7-4 | Fenway Park (21-13) | 37-33 | Won 3 |
| » Starters: Bobo Newsom vs Mickey Harris | Third | 8 out |
| » Defeated Senators (30-38), 10-1 | Fenway Park (22-13) | 38-33 | Won 4 |
| » Starters: Mickey Haefner vs Denny Galehouse | Third | 8 out |
| Future Red Sox Lance Clemons is born in Philadelphia, PA. |
| Thursday, July 10 |
| » Tied Tigers, 2-2 | Tiger Stadium (1-2) | 38-33 | |
| » Starters: Dave Ferriss vs Hal Newhouser | Third | 8½ out |
| » Major-league debuts: Sam Dente (Red Sox) |
| Friday, July 11 |
| » Defeated Tigers (37-33), 4-3 | Tiger Stadium (2-2) | 39-33 | Won 5 |
| » Starters: Tex Hughson vs Dizzy Trout | Third | 9 out |
| » Lost to Tigers (38-33), 3-0 | Tiger Stadium (2-3) | 39-34 | |
| » Starters: Denny Galehouse vs Stubby Overmire | Third | 9 out |
| Saturday, July 12 |
| » Defeated Tigers (38-34), 2-0 | Tiger Stadium (3-3) | 40-34 | |
| » Starters: Earl Johnson vs Al Benton | Second | 9½ out |
| Sunday, July 13 |
| » Lost to Indians (35-34), 8-0 | Cleveland Stadium (3-3) | 40-35 | |
| » Starters: Harry Dorish vs Mel Harder | Third | 11½ out |
| » Lost to Indians (36-34), 6-2 | Cleveland Stadium (3-4) | 40-36 | Lost 2 |
| » Starters: Joe Dobson vs Steve Gromek | Third | 11½ out |
| Monday, July 14 |
| » Defeated Indians (36-35), 1-0 | Cleveland Stadium (4-4) | 41-36 | |
| » Starters: Dave Ferriss vs Don Black | Third | 11 out |
| Tuesday, July 15 |
| » Lost to White Sox (37-44), 5-1 | Comiskey Park I (2-2) | 41-37 | |
| » Starters: Tex Hughson vs Frank Papish | Third | 12½ out |
| Wednesday, July 16 |
| » Defeated White Sox (37-45), 7-2 | Comiskey Park I (3-2) | 42-37 | |
| » Starters: Denny Galehouse vs Red Ruffing | Third | 12½ out |
| Thursday, July 17 |
| » Defeated White Sox (37-46), 4-1 | Comiskey Park I (4-2) | 43-37 | Won 2 |
| » Starters: Joe Dobson vs Ed Lopat | Third | 12½ out |
| » Defeated White Sox (37-47), 6-3 | Comiskey Park I (5-2) | 44-37 | Won 3 |
| » Starters: Harry Dorish vs Bob Gillespie | Third | 12½ out |
| Friday, July 18 |
| » Lost to Browns (29-51), 9-8 | Sportsman's Park III (4-2) | 44-38 | |
| » Starters: Dave Ferriss vs Cliff Fannin | Third | 12½ out |
| Saturday, July 19 |
| » Defeated Browns (29-52), 1-0 | Sportsman's Park III (5-2) | 45-38 | |
| » Starters: Earl Johnson vs Ellis Kinder | Third | 12½ out |
| Sunday, July 20 |
| » Lost to Browns (30-52), 4-3 | Sportsman's Park III (5-3) | 45-39 | |
| » Starters: Tex Hughson vs Jack Kramer | Third | 12½ out |
| » Lost to Browns (31-52), 7-6 | Sportsman's Park III (5-4) | 45-40 | Lost 2 |
| » Starters: Denny Galehouse vs Bob Muncrief | Third | 12½ out |
| Tuesday, July 22 |
| » Defeated White Sox (39-49), 3-2 | Fenway Park (23-13) | 46-40 | |
| » Starters: Ed Lopat vs Joe Dobson | Third | 12½ out |
| Wednesday, July 23 |
| » Defeated White Sox (39-50), 8-7 | Fenway Park (24-13) | 47-40 | Won 2 |
| » Starters: Joe Haynes vs Dave Ferriss | Third | 11½ out |
| Thursday, July 24 |
| » Defeated White Sox (39-51), 8-2 | Fenway Park (25-13) | 48-40 | Won 3 |
| » Starters: Frank Papish vs Denny Galehouse | Third | 11½ out |
| Friday, July 25 |
| » Defeated Browns (32-55), 7-6 | Fenway Park (26-13) | 49-40 | Won 4 |
| » Starters: Jack Kramer vs Earl Johnson | Second | 11½ out |
| Saturday, July 26 |
| » Defeated Browns (32-56), 12-1 | Fenway Park (27-13) | 50-40 | Won 5 |
| » Starters: Cliff Fannin vs Joe Dobson | Second | 10½ out |
| Sunday, July 27 |
| » Defeated Browns (32-57), 4-3 | Fenway Park (28-13) | 51-40 | Won 6 |
| » Starters: Fred Sanford vs Tex Hughson | Second | 9½ out |
| » Defeated Browns (32-58), 11-2 | Fenway Park (29-13) | 52-40 | Won 7 |
| » Starters: Ellis Kinder vs Dave Ferriss | Second | 9½ out |
| Tuesday, July 29 |
| » Lost to Indians (41-45), 5-1 | Fenway Park (29-14) | 52-41 | |
| » Starters: Bob Feller vs Denny Galehouse | Second | 10½ out |
| Wednesday, July 30 |
| » Lost to Indians (42-45), 13-7 | Fenway Park (29-15) | 52-42 | Lost 2 |
| » Starters: Don Black vs Earl Johnson | Second | 11½ out |
| Thursday, July 31 |
| » Lost to Indians (43-45), 5-4 | Fenway Park (29-16) | 52-43 | Lost 3 |
| » Starters: Bob Lemon vs Joe Dobson | Second | 12 out |
| Friday, August 1 |
| » Lost to Tigers (50-43), 3-1 | Fenway Park (29-17) | 52-44 | Lost 4 |
| » Starters: Fred Hutchinson vs Dave Ferriss | Second | 12 out |
| Future Red Sox Tony Muser is born in Van Nuys, CA. |
| Saturday, August 2 |
| » Defeated Tigers (50-44), 2-1 | Fenway Park (30-17) | 53-44 | |
| » Starters: Virgil Trucks vs Tex Hughson | Second | 12½ out |
| Sunday, August 3 |
| » Lost to Tigers (51-44), 10-3 | Fenway Park (30-18) | 53-45 | |
| » Starters: Hal Newhouser vs Denny Galehouse | Second | 13½ out |
| Monday, August 4 |
| Future Red Sox Ken Poulsen is born in Van Nuys, CA. |
| Tuesday, August 5 |
| » Lost to Senators (44-52), 3-1 | Griffith Stadium (1-6) | 53-46 | Lost 2 |
| » Starters: Dave Ferriss vs Walt Masterson | Second | 14 out |
| Future Red Sox Bernie Carbo is born in Detroit, MI. |
| Wednesday, August 6 |
| » Lost to Senators (45-52), 1-0 | Griffith Stadium (1-7) | 53-47 | Lost 3 |
| » Starters: Earl Johnson vs Mickey Haefner | Third | 14 out |
| Thursday, August 7 |
| » Defeated Senators (45-53), 12-2 | Griffith Stadium (2-7) | 54-47 | |
| » Starters: Denny Galehouse vs Early Wynn | Third | 13½ out |
| Friday, August 8 |
| » Defeated Yankees (69-36), 9-6 | Fenway Park (31-18) | 55-47 | Won 2 |
| » Starters: Vic Raschi vs Tex Hughson | Second | 12½ out |
| Saturday, August 9 |
| » Defeated Yankees (69-37), 6-4 | Fenway Park (32-18) | 56-47 | Won 3 |
| » Starters: Allie Reynolds vs Dave Ferriss | Second | 11½ out |
| Future Red Sox Buddy Hunter is born in Omaha, NE. |
| Sunday, August 10 |
| » Lost to Yankees (70-37), 2-1 | Fenway Park (32-19) | 56-48 | |
| » Starters: Karl Drews vs Joe Dobson | Second | 12½ out |
| Monday, August 11 |
| » Defeated Senators (46-56), 1-0 | Fenway Park (33-19) | 57-48 | |
| » Starters: Mickey Haefner vs Earl Johnson | Second | 11½ out |
| Tuesday, August 12 |
| » Defeated Senators (46-57), 2-1 | Fenway Park (34-19) | 58-48 | Won 2 |
| » Starters: Early Wynn vs Denny Galehouse | Second | 11 out |
| Wednesday, August 13 |
| » Defeated Senators (46-58), 10-3 | Fenway Park (35-19) | 59-48 | Won 3 |
| » Starters: Milo Candini vs Tex Hughson | Second | 11 out |
| Friday, August 15 |
| » Lost to Yankees (73-38), 10-6 | Yankee Stadium (1-7) | 59-49 | |
| » Starters: Mickey Harris vs Karl Drews | Second | 12½ out |
| Future Red Sox Billy Conigliaro is born in Revere, MA. |
| Saturday, August 16 |
| » Lost to Yankees (74-38), 1-0 | Yankee Stadium (1-8) | 59-50 | Lost 2 |
| » Starters: Earl Johnson vs Bobo Newsom | Second | 13½ out |
| Sunday, August 17 |
| » Defeated Yankees (74-39), 3-0 | Yankee Stadium (2-8) | 60-50 | |
| » Starters: Denny Galehouse vs Vic Raschi | Second | 12½ out |
| Tuesday, August 19 |
| » Defeated Browns (41-75), 9-5 | Sportsman's Park III (6-4) | 61-50 | Won 2 |
| » Starters: Joe Dobson vs Glen Moulder | Second | 11½ out |
| Thursday, August 21 |
| » Lost to White Sox (54-63), 3-2 | Comiskey Park I (5-3) | 61-51 | |
| » Starters: Tex Hughson vs Frank Papish | Second | 13 out |
| Former Red Sox King Brady dies in Albany, NY at the age of 67. |
| Friday, August 22 |
| » Lost to White Sox (55-63), 7-2 | Comiskey Park I (5-4) | 61-52 | Lost 2 |
| » Starters: Denny Galehouse vs Ed Lopat | Second | 12 out |
| » Defeated White Sox (55-64), 6-3 | Comiskey Park I (6-4) | 62-52 | |
| » Starters: Earl Johnson vs Bob Gillespie | Second | 12 out |
| Sunday, August 24 |
| » Defeated Indians (60-57), 11-2 | Cleveland Stadium (5-4) | 63-52 | Won 2 |
| » Starters: Dave Ferriss vs Mel Harder | Second | 12½ out |
| » Lost to Indians (61-57), 2-1 | Cleveland Stadium (5-5) | 63-53 | |
| » Starters: Mickey Harris vs Al Gettel | Second | 12½ out |
| Monday, August 25 |
| » Lost to Indians (62-57), 10-8 | Cleveland Stadium (5-6) | 63-54 | Lost 2 |
| » Starters: Joe Dobson vs Steve Gromek | Second | 12½ out |
| Tuesday, August 26 |
| » Lost to Tigers (65-56), 12-1 | Tiger Stadium (3-4) | 63-55 | Lost 3 |
| » Starters: Denny Galehouse vs Art Houtteman | Second | 12 out |
| » Defeated Tigers (65-57), 9-1 | Tiger Stadium (4-4) | 64-55 | |
| » Starters: Tex Hughson vs Hal White | Second | 12 out |
| Wednesday, August 27 |
| » Lost to Tigers (66-57), 7-2 | Tiger Stadium (4-5) | 64-56 | |
| » Starters: Earl Johnson vs Stubby Overmire | Second | 12½ out |
| » Defeated Tigers (66-58), 5-4 | Tiger Stadium (5-5) | 65-56 | |
| » Starters: Joe Dobson vs Virgil Trucks | Second | 12½ out |
| Thursday, August 28 |
| » Defeated Tigers (66-59), 13-3 | Tiger Stadium (6-5) | 66-56 | Won 2 |
| » Starters: Eddie Smith vs Hal Newhouser | Second | 12 out |
| Friday, August 29 |
| » Defeated Athletics (65-60), 2-1 | Fenway Park (36-19) | 67-56 | Won 3 |
| » Starters: Joe Coleman vs Mickey Harris | Second | 12 out |
| Saturday, August 30 |
| » Defeated Athletics (65-61), 2-0 | Fenway Park (37-19) | 68-56 | Won 4 |
| » Starters: Bill McCahan vs Tex Hughson | Second | 12 out |
| Sunday, August 31 |
| » Defeated Athletics (65-62), 5-1 | Fenway Park (38-19) | 69-56 | Won 5 |
| » Starters: Carl Scheib vs Joe Dobson | Second | 12½ out |
| Monday, September 1 |
| » Defeated Yankees (83-46), 6-3 | Fenway Park (39-19) | 70-56 | Won 6 |
| » Starters: Karl Drews vs Denny Galehouse | Second | 10½ out |
| » Defeated Yankees (83-47), 4-1 | Fenway Park (40-19) | 71-56 | Won 7 |
| » Starters: Bill Bevens vs Earl Johnson | Second | 10½ out |
| Future Red Sox Craig Skok is born in Dobbs Ferry, NY. |
| Wednesday, September 3 |
| » Lost to Yankees (84-47), 11-2 | Fenway Park (40-20) | 71-57 | |
| » Starters: Bobo Newsom vs Tex Hughson | Second | 12½ out |
| » Lost to Yankees (85-47), 9-6 | Fenway Park (40-21) | 71-58 | Lost 2 |
| » Starters: Spec Shea vs Eddie Smith | Second | 12½ out |
| Friday, September 5 |
| » Lost to Athletics (67-65), 9-7 | Shibe Park (4-4) | 71-59 | Lost 3 |
| » Starters: Joe Dobson vs Phil Marchildon | Second | 12 out |
| Saturday, September 6 |
| » Defeated Athletics (67-66), 4-3 | Shibe Park (5-4) | 72-59 | |
| » Starters: Earl Johnson vs Dick Fowler | Second | 11 out |
| Sunday, September 7 |
| » Lost to Athletics (68-66), 7-4 | Shibe Park (5-5) | 72-60 | |
| » Starters: Denny Galehouse vs Joe Coleman | Second | 12½ out |
| » Lost to Athletics (69-66), 4-3 | Shibe Park (5-6) | 72-61 | Lost 2 |
| » Starters: Eddie Smith vs Bill McCahan | Second | 12½ out |
| Tuesday, September 9 |
| » Defeated Tigers (72-63), 5-3 | Fenway Park (41-21) | 73-61 | |
| » Starters: Virgil Trucks vs Joe Dobson | Second | 11½ out |
| Wednesday, September 10 |
| » Lost to Tigers (73-63), 5-0 | Fenway Park (41-22) | 73-62 | |
| » Starters: Fred Hutchinson vs Earl Johnson | Second | 12½ out |
| » Major-league debuts: Matt Batts (Red Sox) |
| Thursday, September 11 |
| » Lost to Indians (72-64), 10-8 | Fenway Park (41-23) | 73-63 | Lost 2 |
| » Starters: Don Black vs Cot Deal | Second | 12½ out |
| » Defeated Indians (72-65), 8-3 | Fenway Park (42-23) | 74-63 | |
| » Starters: Al Gettel vs Dave Ferriss | Second | 12½ out |
| » Major-league debuts: Ernest Groth (Indians) |
| Friday, September 12 |
| » Lost to Indians (73-65), 11-6 | Fenway Park (42-24) | 74-64 | |
| » Starters: Bob Lemon vs Denny Galehouse | Third | 12½ out |
| » Major-league debuts: Merl Combs (Red Sox) |
| Saturday, September 13 |
| » Defeated Indians (73-66), 3-2 | Fenway Park (43-24) | 75-64 | |
| » Starters: Bob Feller vs Earl Johnson | Second | 12½ out |
| Sunday, September 14 |
| » Tied White Sox, 1-1 | Fenway Park (43-24) | 75-64 | |
| » Starters: Ed Lopat vs Joe Dobson | Third | 13 out |
| Monday, September 15 |
| » Lost to White Sox (66-75), 6-3 | Fenway Park (43-25) | 75-65 | |
| » Starters: Orval Grove vs Dave Ferriss | Third | 13 out |
| » Defeated White Sox (66-76), 7-5 | Fenway Park (44-25) | 76-65 | |
| » Starters: Red Ruffing vs Harry Dorish | Third | 13 out |
| » Major-league debuts: Chuck Stobbs (Red Sox) |
| Tuesday, September 16 |
| » Defeated White Sox (66-77), 5-0 | Fenway Park (45-25) | 77-65 | Won 2 |
| » Starters: Frank Papish vs Denny Galehouse | Third | 13 out |
| » Lost to White Sox (67-77), 8-3 | Fenway Park (45-26) | 77-66 | |
| » Starters: Joe Haynes vs Cot Deal | Third | 13 out |
| Wednesday, September 17 |
| » Lost to Browns (55-88), 9-4 | Fenway Park (45-27) | 77-67 | Lost 2 |
| » Starters: Bob Muncrief vs Earl Johnson | Second | 13½ out |
| » Defeated Browns (55-89), 4-0 | Fenway Park (46-27) | 78-67 | |
| » Starters: Jack Kramer vs Joe Dobson | Second | 13½ out |
| Thursday, September 18 |
| » Defeated Browns (55-90), 10-6 | Fenway Park (47-27) | 79-67 | Won 2 |
| » Starters: Cliff Fannin vs Tommy Fine | Second | 13½ out |
| Saturday, September 20 |
| » Lost to Senators (61-85), 6-3 | Fenway Park (47-28) | 79-68 | |
| » Starters: Early Wynn vs Earl Johnson | Second | 13 out |
| » Defeated Senators (61-86), 7-2 | Fenway Park (48-28) | 80-68 | |
| » Starters: Hal Toenes vs Denny Galehouse | Second | 13 out |
| Sunday, September 21 |
| » Lost to Senators (62-86), 3-0 | Fenway Park (48-29) | 80-69 | |
| » Starters: Ray Scarborough vs Joe Dobson | Second | 14 out |
| Tuesday, September 23 |
| » Lost to Athletics (76-73), 9-3 | Fenway Park (48-30) | 80-70 | Lost 2 |
| » Starters: Phil Marchildon vs Chuck Stobbs | Third | 15 out |
| » Defeated Athletics (76-74), 6-5 | Fenway Park (49-30) | 81-70 | |
| » Starters: Bill Dietrich vs Earl Johnson | Third | 15 out |
| Friday, September 26 |
| » Defeated Yankees (96-56), 3-2 | Yankee Stadium (3-8) | 82-70 | Won 2 |
| » Starters: Denny Galehouse vs Spud Chandler | Third | 14 out |
| Saturday, September 27 |
| » Defeated Senators (63-90), 8-1 | Griffith Stadium (3-7) | 83-70 | Won 3 |
| » Starters: Joe Dobson vs Walt Masterson | Third | 13 out |
| Sunday, September 28 |
| » Lost to Senators (64-90), 5-1 | Griffith Stadium (3-8) | 83-71 | | <