| Saturday, January 4 |
| Future Cardinal Ken Reynolds is born in Trevose, PA. |
| Tuesday, January 21 |
| Future Cardinal Bob Reynolds is born in Seattle, WA. Future Cardinal Bill Stein is born in Battle Creek, MI. |
| Monday, January 27 |
| Future Cardinal Tim Plodinec is born in Aliquippa, PA. |
| Wednesday, January 29 |
| Former Cardinal Del Gainer dies in Elkins, WV at the age of 61. |
| Thursday, March 20 |
| Former Cardinal Mike Mowrey dies in Chambersburg, PA at the age of 63. |
| Tuesday, April 15 |
| » Lost to Reds (1-0), 3-1 | Crosley Field (0-1) | 0-1 | |
| » Starters: Howie Pollet vs Ewell Blackwell | Second | 1 out |
| » Major-league debuts: Frankie Baumholtz (Reds) Chuck Diering (Cardinals) |
| Wednesday, April 16 |
| » Defeated Reds (1-1), 4-1 | Crosley Field (1-1) | 1-1 | |
| » Starters: Red Munger vs Eddie Erautt | Second | ½ out |
| » Major-league debuts: Eddie Erautt (Reds) |
| Thursday, April 17 |
| » Lost to Reds (2-1), 9-4 | Crosley Field (1-2) | 1-2 | |
| » Starters: Murry Dickson vs Buddy Lively | Third | 1½ out |
| » Major-league debuts: Jim Hearn (Cardinals) |
| Friday, April 18 |
| » Defeated Cubs (0-3), 4-1 | Sportsman's Park III (1-0) | 2-2 | |
| » Starters: Johnny Schmitz vs Harry Brecheen | Third | 1½ out |
| Saturday, April 19 |
| » Lost to Cubs (1-3), 7-1 | Sportsman's Park III (1-1) | 2-3 | |
| » Starters: Bob Chipman vs Al Brazle | Fourth | 2½ out |
| Sunday, April 20 |
| » Lost to Cubs (2-3), 7-4 | Sportsman's Park III (1-2) | 2-4 | Lost 2 |
| » Starters: Hank Borowy vs Howie Pollet | Sixth | 3 out |
| » Major-league debuts: Gerry Staley (Cardinals) |
| Wednesday, April 23 |
| » Lost to Pirates (6-1), 8-5 | Sportsman's Park III (1-3) | 2-5 | Lost 3 |
| » Starters: Ken Heintzelman vs Red Munger | Seventh | 4 out |
| Saturday, April 26 |
| » Lost to Cubs (6-4), 4-1 | Wrigley Field (0-1) | 2-6 | Lost 4 |
| » Starters: Harry Brecheen vs Bob Chipman | Seventh | 4 out |
| Sunday, April 27 |
| » Lost to Cubs (7-4), 3-0 | Wrigley Field (0-2) | 2-7 | Lost 5 |
| » Starters: Murry Dickson vs Johnny Schmitz | Seventh | 5 out |
| Tuesday, April 29 |
| » Lost to Giants (3-7), 7-2 | Polo Grounds V (0-1) | 2-8 | Lost 6 |
| » Starters: Howie Pollet vs Monte Kennedy | Seventh | 6 out |
| Wednesday, April 30 |
| » Lost to Giants (4-7), 4-3 | Polo Grounds V (0-2) | 2-9 | Lost 7 |
| » Starters: Red Munger vs Bill Voiselle | Seventh | 6 out |
| Thursday, May 1 |
| » Lost to Giants (5-7), 6-5 | Polo Grounds V (0-3) | 2-10 | Lost 8 |
| » Starters: Al Brazle vs Dave Koslo | Eighth | 7 out |
| Sunday, May 4 |
| » Lost to Braves (8-5), 4-3 | Braves Field (0-1) | 2-11 | Lost 9 |
| » Starters: Murry Dickson vs Warren Spahn | Seventh | 7 out |
| » Defeated Braves (8-6), 9-0 | Braves Field (1-1) | 3-11 | |
| » Starters: Harry Brecheen vs Mort Cooper | Seventh | 7 out |
| Tuesday, May 6 |
| » Lost to Dodgers (10-3), 7-6 | Ebbets Field (0-1) | 3-12 | |
| » Starters: Red Munger vs Joe Hatten | Seventh | 8 out |
| Wednesday, May 7 |
| » Defeated Dodgers (10-4), 2-1 | Ebbets Field (1-1) | 4-12 | |
| » Starters: Howie Pollet vs Vic Lombardi | Eighth | 7 out |
| Thursday, May 8 |
| » Defeated Dodgers (10-5), 5-1 | Ebbets Field (2-1) | 5-12 | Won 2 |
| » Starters: Harry Brecheen vs Ralph Branca | Sixth | 6 out |
| Saturday, May 10 |
| » Lost to Pirates (9-8), 3-0 | Forbes Field (0-1) | 5-13 | |
| » Starters: Murry Dickson vs Fritz Ostermueller | Sixth | 6½ out |
| Future Cardinal John Cumberland is born in Westbrook, ME. |
| Sunday, May 11 |
| » Defeated Pirates (9-9), 10-6 | Forbes Field (1-1) | 6-13 | |
| » Starters: Red Munger vs Preacher Roe | Eighth | 7 out |
| » Tied Pirates, 3-3 | Forbes Field (1-1) | 6-13 | |
| » Starters: Ken Burkhart vs Kirby Higbe | Eighth | 7 out |
| Monday, May 12 |
| Future Cardinal Bob Heise is born in San Antonio, TX. |
| Tuesday, May 13 |
| » Lost to Giants (9-10), 5-0 | Sportsman's Park III (1-4) | 6-14 | |
| » Starters: Dave Koslo vs Howie Pollet | Eighth | 7 out |
| Wednesday, May 14 |
| » Lost to Giants (10-10), 6-4 | Sportsman's Park III (1-5) | 6-15 | Lost 2 |
| » Starters: Larry Jansen vs Murry Dickson | Eighth | 7½ out |
| Thursday, May 15 |
| » Defeated Braves (14-10), 8-2 | Sportsman's Park III (2-5) | 7-15 | |
| » Starters: Johnny Sain vs Harry Brecheen | Eighth | 6½ out |
| Friday, May 16 |
| » Defeated Braves (14-11), 4-3 | Sportsman's Park III (3-5) | 8-15 | Won 2 |
| » Starters: Si Johnson vs Red Munger | Eighth | 5½ out |
| Saturday, May 17 |
| » Lost to Braves (15-11), 3-2 | Sportsman's Park III (3-6) | 8-16 | |
| » Starters: Warren Spahn vs Howie Pollet | Eighth | 6 out |
| Sunday, May 18 |
| » Lost to Phillies (14-13), 6-3 | Sportsman's Park III (3-7) | 8-17 | Lost 2 |
| » Starters: Ken Heintzelman vs Murry Dickson | Seventh | 7 out |
| » Lost to Phillies (15-13), 1-0 | Sportsman's Park III (3-8) | 8-18 | Lost 3 |
| » Starters: Ken Raffensberger vs Al Brazle | Seventh | 7 out |
| Monday, May 19 |
| » Defeated Phillies (15-14), 5-3 | Sportsman's Park III (4-8) | 9-18 | |
| » Starters: Oscar Judd vs Jim Hearn | Eighth | 6½ out |
| Wednesday, May 21 |
| » Lost to Dodgers (15-13), 4-3 | Sportsman's Park III (4-9) | 9-19 | |
| » Starters: Joe Hatten vs Harry Brecheen | Eighth | 7½ out |
| Thursday, May 22 |
| » Defeated Pirates (13-12), 4-1 | Sportsman's Park III (5-9) | 10-19 | |
| » Starters: Kirby Higbe vs Howie Pollet | Eighth | 7 out |
| Friday, May 23 |
| » Defeated Pirates (13-13), 2-0 | Sportsman's Park III (6-9) | 11-19 | Won 2 |
| » Starters: Preacher Roe vs Red Munger | Eighth | 6½ out |
| Sunday, May 25 |
| » Defeated Pirates (13-14), 10-5 | Sportsman's Park III (7-9) | 12-19 | Won 3 |
| » Starters: Hank Behrman vs Al Brazle | Eighth | 6½ out |
| » Lost to Pirates (14-14), 2-1 | Sportsman's Park III (7-10) | 12-20 | |
| » Starters: Fritz Ostermueller vs Jim Hearn | Eighth | 6½ out |
| Monday, May 26 |
| » Defeated Cubs (18-14), 3-1 | Sportsman's Park III (8-10) | 13-20 | |
| » Starters: Johnny Schmitz vs Harry Brecheen | Eighth | 6 out |
| Tuesday, May 27 |
| » Lost to Cubs (19-14), 10-3 | Sportsman's Park III (8-11) | 13-21 | |
| » Starters: Bob Chipman vs Howie Pollet | Eighth | 6½ out |
| Former Cardinal Ed Konetchy dies in Ft.Worth, TX at the age of 62. |
| Wednesday, May 28 |
| » Defeated Reds (15-21), 4-2 | Sportsman's Park III (9-11) | 14-21 | |
| » Starters: Eddie Erautt vs Red Munger | Eighth | 6 out |
| Friday, May 30 |
| » Lost to Reds (16-21), 12-8 | Sportsman's Park III (9-12) | 14-22 | |
| » Starters: Johnny Vander Meer vs Jim Hearn | Seventh | 6½ out |
| » Defeated Reds (16-22), 7-3 | Sportsman's Park III (10-12) | 15-22 | |
| » Starters: Kent Peterson vs Al Brazle | Seventh | 6½ out |
| Saturday, May 31 |
| Former Cardinal Jimmie Wilson dies in Bradenton, FL at the age of 47. |
| Sunday, June 1 |
| » Lost to Dodgers (21-17), 6-1 | Ebbets Field (2-2) | 15-23 | |
| » Starters: Harry Brecheen vs Harry Taylor | Seventh | 7½ out |
| Monday, June 2 |
| » Defeated Dodgers (21-18), 5-4 | Ebbets Field (3-2) | 16-23 | |
| » Starters: Howie Pollet vs Joe Hatten | Seventh | 6½ out |
| Tuesday, June 3 |
| » Defeated Braves (22-19), 3-0 | Braves Field (2-1) | 17-23 | Won 2 |
| » Starters: Red Munger vs Warren Spahn | Eighth | 6½ out |
| Wednesday, June 4 |
| » Lost to Braves (23-19), 3-1 | Braves Field (2-2) | 17-24 | |
| » Starters: Al Brazle vs Red Barrett | Seventh | 6½ out |
| Thursday, June 5 |
| » Defeated Braves (23-20), 5-3 | Braves Field (3-2) | 18-24 | |
| » Starters: Harry Brecheen vs Johnny Sain | Seventh | 6½ out |
| Friday, June 6 |
| » Lost to Giants (25-18), 7-4 | Polo Grounds V (0-4) | 18-25 | |
| » Starters: Howie Pollet vs Bill Ayers | Eighth | 7½ out |
| Monday, June 9 |
| » Defeated Phillies (21-27), 4-2 | Shibe Park (1-0) | 19-25 | |
| » Starters: Al Brazle vs Ken Heintzelman | Seventh | 7½ out |
| » Lost to Phillies (22-27), 2-1 | Shibe Park (1-1) | 19-26 | |
| » Starters: Red Munger vs Schoolboy Rowe | Seventh | 7½ out |
| Tuesday, June 10 |
| » Defeated Phillies (22-28), 8-3 | Shibe Park (2-1) | 20-26 | |
| » Starters: Harry Brecheen vs Oscar Judd | Fifth | 7½ out |
| Wednesday, June 11 |
| » Lost to Phillies (23-28), 5-4 | Shibe Park (2-2) | 20-27 | |
| » Starters: Howie Pollet vs Ken Raffensberger | Sixth | 7½ out |
| Thursday, June 12 |
| » Lost to Reds (24-28), 1-0 | Crosley Field (1-3) | 20-28 | Lost 2 |
| » Starters: Jim Hearn vs Kent Peterson | Sixth | 8 out |
| Friday, June 13 |
| » Defeated Dodgers (27-22), 3-0 | Sportsman's Park III (11-12) | 21-28 | |
| » Starters: Harry Taylor vs Red Munger | Seventh | 7½ out |
| Saturday, June 14 |
| » Defeated Dodgers (27-23), 5-3 | Sportsman's Park III (12-12) | 22-28 | Won 2 |
| » Starters: Ralph Branca vs Al Brazle | Sixth | 6½ out |
| » Defeated Dodgers (27-24), 12-2 | Sportsman's Park III (13-12) | 23-28 | Won 3 |
| » Starters: Rex Barney vs Harry Brecheen | Sixth | 6½ out |
| Sunday, June 15 |
| » Defeated Dodgers (27-25), 11-3 | Sportsman's Park III (14-12) | 24-28 | Won 4 |
| » Starters: Joe Hatten vs Howie Pollet | Sixth | 6 out |
| Monday, June 16 |
| » Defeated Phillies (24-31), 4-3 | Sportsman's Park III (15-12) | 25-28 | Won 5 |
| » Starters: Ken Heintzelman vs Jim Hearn | Sixth | 5½ out |
| Tuesday, June 17 |
| » Defeated Phillies (24-32), 7-6 | Sportsman's Park III (16-12) | 26-28 | Won 6 |
| » Starters: Charley Schanz vs Red Munger | Fifth | 5½ out |
| Wednesday, June 18 |
| » Defeated Phillies (24-33), 5-2 | Sportsman's Park III (17-12) | 27-28 | Won 7 |
| » Starters: Oscar Judd vs Al Brazle | Fifth | 4½ out |
| Friday, June 20 |
| » Defeated Giants (29-23), 7-3 | Sportsman's Park III (18-12) | 28-28 | Won 8 |
| » Starters: Dave Koslo vs Harry Brecheen | Fourth | 3½ out |
| Former Cardinal Bob Ewing dies in Wapakoneta, OH at the age of 75. |
| Saturday, June 21 |
| » Defeated Giants (29-24), 11-5 | Sportsman's Park III (19-12) | 29-28 | Won 9 |
| » Starters: Clint Hartung vs Howie Pollet | Fifth | 3½ out |
| Sunday, June 22 |
| » Lost to Giants (30-24), 7-5 | Sportsman's Park III (19-13) | 29-29 | |
| » Starters: Larry Jansen vs Jim Hearn | Fifth | 4½ out |
| Monday, June 23 |
| » Defeated Braves (33-25), 6-2 | Sportsman's Park III (20-13) | 30-29 | |
| » Starters: Red Barrett vs Red Munger | Fifth | 3½ out |
| Tuesday, June 24 |
| » Lost to Braves (34-25), 9-6 | Sportsman's Park III (20-14) | 30-30 | |
| » Starters: Warren Spahn vs Al Brazle | Fifth | 4½ out |
| Thursday, June 26 |
| » Lost to Reds (31-32), 6-3 | Sportsman's Park III (20-15) | 30-31 | Lost 2 |
| » Starters: Ewell Blackwell vs Harry Brecheen | Fifth | 5 out |
| Friday, June 27 |
| » Defeated Reds (31-33), 6-5 | Sportsman's Park III (21-15) | 31-31 | |
| » Starters: Ken Raffensberger vs Howie Pollet | Fourth | 5 out |
| Saturday, June 28 |
| » Defeated Reds (31-34), 8-7 | Sportsman's Park III (22-15) | 32-31 | Won 2 |
| » Starters: Kent Peterson vs Red Munger | Fifth | 4 out |
| Sunday, June 29 |
| » Lost to Reds (32-34), 9-7 | Sportsman's Park III (22-16) | 32-32 | |
| » Starters: Johnny Vander Meer vs Murry Dickson | Fourth | 4½ out |
| » Defeated Reds (32-35), 17-2 | Sportsman's Park III (23-16) | 33-32 | |
| » Starters: Bucky Walters vs Al Brazle | Fourth | 4½ out |
| Tuesday, July 1 |
| » Defeated Pirates (25-39), 2-1 | Forbes Field (2-1) | 34-32 | Won 2 |
| » Starters: Jim Hearn vs Tiny Bonham | Fourth | 3½ out |
| Thursday, July 3 |
| » Lost to Cubs (34-33), 4-2 | Wrigley Field (0-3) | 34-33 | |
| » Starters: Harry Brecheen vs Hank Borowy | Fourth | 4 out |
| Friday, July 4 |
| » Defeated Cubs (34-34), 7-0 | Wrigley Field (1-3) | 35-33 | |
| » Starters: Red Munger vs Bob Chipman | Fourth | 5 out |
| » Lost to Cubs (35-34), 5-4 | Wrigley Field (1-4) | 35-34 | |
| » Starters: Howie Pollet vs Johnny Schmitz | Fourth | 5 out |
| Saturday, July 5 |
| » Lost to Reds (37-36), 7-5 | Crosley Field (1-4) | 35-35 | Lost 2 |
| » Starters: Al Brazle vs Ken Raffensberger | Sixth | 5 out |
| Sunday, July 6 |
| » Defeated Reds (37-37), 3-0 | Crosley Field (2-4) | 36-35 | |
| » Starters: Jim Hearn vs Johnny Vander Meer | Fourth | 4½ out |
| » Defeated Reds (37-38), 2-0 | Crosley Field (3-4) | 37-35 | Won 2 |
| » Starters: Murry Dickson vs Kent Peterson | Fourth | 4½ out |
| Future Cardinal Lance Clemons is born in Philadelphia, PA. |
| Thursday, July 10 |
| » Defeated Giants (38-31), 11-4 | Polo Grounds V (1-4) | 38-35 | Won 3 |
| » Starters: Red Munger vs Clint Hartung | Fourth | 5 out |
| Friday, July 11 |
| » Defeated Giants (38-32), 4-3 | Polo Grounds V (2-4) | 39-35 | Won 4 |
| » Starters: Al Brazle vs Dave Koslo | Fourth | 5½ out |
| » Lost to Giants (39-32), 17-9 | Polo Grounds V (2-5) | 39-36 | |
| » Starters: Jim Hearn vs Monte Kennedy | Fourth | 5½ out |
| Saturday, July 12 |
| » Defeated Giants (39-33), 4-0 | Polo Grounds V (3-5) | 40-36 | |
| » Starters: Murry Dickson vs Monte Kennedy | Fourth | 5½ out |
| » Defeated Giants (39-34), 11-3 | Polo Grounds V (4-5) | 41-36 | Won 2 |
| » Starters: Harry Brecheen vs Hooks Iott | Fourth | 5½ out |
| Future Cardinal Scipio Spinks is born in Chicago, IL. |
| Sunday, July 13 |
| » Lost to Phillies (34-45), 4-2 | Shibe Park (2-3) | 41-37 | |
| » Starters: Ken Burkhart vs Ken Heintzelman | Fourth | 6 out |
| » Defeated Phillies (34-46), 3-2 | Shibe Park (3-3) | 42-37 | |
| » Starters: Howie Pollet vs Oscar Judd | Fourth | 6 out |
| Monday, July 14 |
| » Lost to Phillies (35-46), 5-2 | Shibe Park (3-4) | 42-38 | |
| » Starters: Red Munger vs Tommy Hughes | Fourth | 6 out |
| Tuesday, July 15 |
| » Defeated Braves (44-35), 8-2 | Braves Field (4-2) | 43-38 | |
| » Starters: Jim Hearn vs Walt Lanfranconi | Fourth | 4½ out |
| Wednesday, July 16 |
| » Lost to Braves (45-35), 3-0 | Braves Field (4-3) | 43-39 | |
| » Starters: Murry Dickson vs Warren Spahn | Fourth | 5½ out |
| Thursday, July 17 |
| » Defeated Braves (45-36), 5-2 | Braves Field (5-3) | 44-39 | |
| » Starters: Harry Brecheen vs Red Barrett | Fourth | 4½ out |
| Friday, July 18 |
| » Lost to Dodgers (50-35), 7-0 | Ebbets Field (3-3) | 44-40 | |
| » Starters: Red Munger vs Ralph Branca | Fourth | 5½ out |
| Saturday, July 19 |
| » Defeated Dodgers (50-36), 7-5 | Ebbets Field (4-3) | 45-40 | |
| » Starters: Howie Pollet vs Vic Lombardi | Fourth | 4½ out |
| Sunday, July 20 |
| » Tied Dodgers, 3-3 | Ebbets Field (4-3) | 45-40 | |
| » Starters: Jim Hearn vs Harry Taylor | Fourth | 4½ out |
| Tuesday, July 22 |
| » Defeated Giants (45-37), 10-5 | Sportsman's Park III (24-16) | 46-40 | Won 2 |
| » Starters: Monte Kennedy vs Harry Brecheen | Fourth | 5½ out |
| Wednesday, July 23 |
| » Defeated Giants (45-38), 6-5 | Sportsman's Park III (25-16) | 47-40 | Won 3 |
| » Starters: Dave Koslo vs Red Munger | Fourth | 5½ out |
| Thursday, July 24 |
| » Defeated Giants (45-39), 3-2 | Sportsman's Park III (26-16) | 48-40 | Won 4 |
| » Starters: Larry Jansen vs Murry Dickson | Second | 5½ out |
| Friday, July 25 |
| » Defeated Braves (48-41), 5-1 | Sportsman's Park III (27-16) | 49-40 | Won 5 |
| » Starters: Red Barrett vs Howie Pollet | Second | 5½ out |
| Future Cardinal Mick Kelleher is born in Seattle, WA. |
| Saturday, July 26 |
| » Defeated Braves (48-42), 9-5 | Sportsman's Park III (28-16) | 50-40 | Won 6 |
| » Starters: Bill Voiselle vs Jim Hearn | Second | 5½ out |
| Sunday, July 27 |
| » Lost to Braves (49-42), 10-3 | Sportsman's Park III (28-17) | 50-41 | |
| » Starters: Johnny Sain vs Harry Brecheen | Second | 7 out |
| Monday, July 28 |
| » Defeated Braves (49-43), 8-7 | Sportsman's Park III (29-17) | 51-41 | |
| » Starters: Warren Spahn vs Red Munger | Second | 7 out |
| Tuesday, July 29 |
| » Lost to Dodgers (61-36), 4-0 | Sportsman's Park III (29-18) | 51-42 | |
| » Starters: Harry Taylor vs Murry Dickson | Second | 8 out |
| Wednesday, July 30 |
| » Lost to Dodgers (62-36), 11-10 | Sportsman's Park III (29-19) | 51-43 | Lost 2 |
| » Starters: Ralph Branca vs Harry Brecheen | Third | 9 out |
| Thursday, July 31 |
| » Lost to Dodgers (63-36), 2-1 | Sportsman's Park III (29-20) | 51-44 | Lost 3 |
| » Starters: Vic Lombardi vs Howie Pollet | Third | 10 out |
| Friday, August 1 |
| » Defeated Phillies (40-58), 6-1 | Sportsman's Park III (30-20) | 52-44 | |
| » Starters: Schoolboy Rowe vs Murry Dickson | Third | 9 out |
| Saturday, August 2 |
| » Defeated Phillies (40-59), 4-3 | Sportsman's Park III (31-20) | 53-44 | Won 2 |
| » Starters: Oscar Judd vs Jim Hearn | Second | 8 out |
| Sunday, August 3 |
| » Defeated Phillies (40-60), 10-8 | Sportsman's Park III (32-20) | 54-44 | Won 3 |
| » Starters: Freddy Schmidt vs Ken Burkhart | Second | 7 out |
| Former Cardinal Vic Willis dies in Elkton, MD at the age of 72. |
| Monday, August 4 |
| » Defeated Cubs (47-53), 8-1 | Wrigley Field (2-4) | 55-44 | Won 4 |
| » Starters: Howie Pollet vs Bob Chipman | Second | 7 out |
| Tuesday, August 5 |
| » Defeated Cubs (47-54), 8-2 | Wrigley Field (3-4) | 56-44 | Won 5 |
| » Starters: Harry Brecheen vs Claude Passeau | Second | 6 out |
| Future Cardinal Bernie Carbo is born in Detroit, MI. |
| Wednesday, August 6 |
| » Defeated Reds (51-56), 6-3 | Crosley Field (4-4) | 57-44 | Won 6 |
| » Starters: Murry Dickson vs Johnny Vander Meer | Second | 5 out |
| Thursday, August 7 |
| » Defeated Reds (51-57), 9-2 | Crosley Field (5-4) | 58-44 | Won 7 |
| » Starters: Jim Hearn vs Kent Peterson | Second | 4 out |
| Friday, August 8 |
| » Defeated Pirates (44-61), 6-0 | Sportsman's Park III (33-20) | 59-44 | Won 8 |
| » Starters: Fritz Ostermueller vs Red Munger | Second | 4 out |
| Future Cardinal Jose Cruz is born in Arroyo, P.R. |
| Saturday, August 9 |
| » Lost to Pirates (45-61), 5-4 | Sportsman's Park III (33-21) | 59-45 | |
| » Starters: Mel Queen vs Howie Pollet | Second | 4 out |
| Sunday, August 10 |
| » Defeated Pirates (45-62), 5-0 | Sportsman's Park III (34-21) | 60-45 | |
| » Starters: Preacher Roe vs Murry Dickson | Second | 3½ out |
| » Defeated Pirates (45-63), 7-5 | Sportsman's Park III (35-21) | 61-45 | Won 2 |
| » Starters: Tiny Bonham vs Ken Burkhart | Second | 3½ out |
| Monday, August 11 |
| » Defeated Cubs (50-58), 3-1 | Sportsman's Park III (36-21) | 62-45 | Won 3 |
| » Starters: Hank Borowy vs Harry Brecheen | Second | 3 out |
| Tuesday, August 12 |
| » Lost to Cubs (51-58), 2-1 | Sportsman's Park III (36-22) | 62-46 | |
| » Starters: Johnny Schmitz vs Jim Hearn | Second | 3 out |
| Thursday, August 14 |
| » Lost to Pirates (48-64), 5-3 | Forbes Field (2-2) | 62-47 | Lost 2 |
| » Starters: Murry Dickson vs Fritz Ostermueller | Second | 4½ out |
| Friday, August 15 |
| » Defeated Pirates (48-65), 7-4 | Forbes Field (3-2) | 63-47 | |
| » Starters: Red Munger vs Tiny Bonham | Second | 4½ out |
| Saturday, August 16 |
| » Lost to Pirates (49-65), 12-7 | Forbes Field (3-3) | 63-48 | |
| » Starters: Ken Burkhart vs Roger Wolff | Second | 5½ out |
| Sunday, August 17 |
| » Defeated Pirates (49-66), 6-5 | Forbes Field (4-3) | 64-48 | |
| » Starters: Jim Hearn vs Kirby Higbe | Second | 5 out |
| Monday, August 18 |
| » Lost to Dodgers (72-45), 7-5 | Ebbets Field (4-4) | 64-49 | |
| » Starters: Howie Pollet vs Vic Lombardi | Second | 7 out |
| » Lost to Dodgers (73-45), 12-3 | Ebbets Field (4-5) | 64-50 | Lost 2 |
| » Starters: Harry Brecheen vs Harry Taylor | Second | 7 out |
| Future Cardinal Lowell Palmer is born in Sacramento, CA. |
| Tuesday, August 19 |
| » Defeated Dodgers (73-46), 11-3 | Ebbets Field (5-5) | 65-50 | |
| » Starters: Al Brazle vs Joe Hatten | Second | 6 out |
| Wednesday, August 20 |
| » Defeated Dodgers (73-47), 3-2 | Ebbets Field (6-5) | 66-50 | Won 2 |
| » Starters: Murry Dickson vs Ralph Branca | Second | 5 out |
| Thursday, August 21 |
| » Lost to Phillies (48-69), 9-2 | Shibe Park (3-5) | 66-51 | |
| » Starters: Red Munger vs Oscar Judd | Second | 5½ out |
| » Defeated Phillies (48-70), 13-3 | Shibe Park (4-5) | 67-51 | |
| » Starters: Jim Hearn vs Tommy Hughes | Second | 5½ out |
| Friday, August 22 |
| » Lost to Phillies (49-70), 4-2 | Shibe Park (4-6) | 67-52 | |
| » Starters: Harry Brecheen vs Dutch Leonard | Second | 6½ out |
| Saturday, August 23 |
| » Defeated Phillies (49-71), 5-3 | Shibe Park (5-6) | 68-52 | |
| » Starters: Howie Pollet vs Ken Heintzelman | Second | 6½ out |
| Sunday, August 24 |
| » Defeated Braves (67-55), 9-5 | Braves Field (6-3) | 69-52 | Won 2 |
| » Starters: Murry Dickson vs Johnny Sain | Second | 6½ out |
| Monday, August 25 |
| » Defeated Braves (67-56), 5-2 | Braves Field (7-3) | 70-52 | Won 3 |
| » Starters: Red Munger vs Warren Spahn | Second | 6½ out |
| Tuesday, August 26 |
| » Lost to Braves (68-56), 5-1 | Braves Field (7-4) | 70-53 | |
| » Starters: Al Brazle vs Bill Voiselle | Second | 6½ out |
| Wednesday, August 27 |
| » Lost to Giants (63-59), 6-4 | Polo Grounds V (4-6) | 70-54 | Lost 2 |
| » Starters: Harry Brecheen vs Ray Poat | Second | 6½ out |
| Thursday, August 28 |
| » Lost to Giants (64-59), 6-5 | Polo Grounds V (4-7) | 70-55 | Lost 3 |
| » Starters: Murry Dickson vs Larry Jansen | Second | 7½ out |
| Saturday, August 30 |
| » Defeated Reds (61-70), 5-2 | Crosley Field (6-4) | 71-55 | |
| » Starters: Red Munger vs Bucky Walters | Second | 8 out |
| Sunday, August 31 |
| » Defeated Reds (61-71), 15-8 | Crosley Field (7-4) | 72-55 | Won 2 |
| » Starters: Howie Pollet vs Buddy Lively | Second | 8 out |
| Future Cardinal Boots Day is born in Ilion, NY. |
| Monday, September 1 |
| » Defeated Pirates (54-75), 6-5 | Sportsman's Park III (37-22) | 73-55 | Won 3 |
| » Starters: Fritz Ostermueller vs Murry Dickson | Second | 7 out |
| » Defeated Pirates (54-76), 8-2 | Sportsman's Park III (38-22) | 74-55 | Won 4 |
| » Starters: Preacher Roe vs Jim Hearn | Second | 7 out |
| Wednesday, September 3 |
| » Defeated Cubs (58-73), 11-1 | Wrigley Field (4-4) | 75-55 | Won 5 |
| » Starters: Red Munger vs Johnny Schmitz | Second | 6½ out |
| Friday, September 5 |
| Former Cardinal Bill Ludwig dies in Louisville, KY at the age of 66. |
| Saturday, September 6 |
| » Defeated Reds (64-73), 4-3 | Sportsman's Park III (39-22) | 76-55 | Won 6 |
| » Starters: Johnny Vander Meer vs Harry Brecheen | Second | 6½ out |
| Sunday, September 7 |
| » Defeated Reds (64-74), 12-2 | Sportsman's Park III (40-22) | 77-55 | Won 7 |
| » Starters: Ewell Blackwell vs Red Munger | Second | 6 out |
| » Lost to Reds (65-74), 4-2 | Sportsman's Park III (40-23) | 77-56 | |
| » Starters: Ken Raffensberger vs Jim Hearn | Second | 6 out |
| Tuesday, September 9 |
| » Defeated Phillies (55-81), 2-0 | Sportsman's Park III (41-23) | 78-56 | |
| » Starters: Oscar Judd vs Murry Dickson | Second | 5 out |
| Wednesday, September 10 |
| » Defeated Phillies (55-82), 4-1 | Sportsman's Park III (42-23) | 79-56 | Won 2 |
| » Starters: Dutch Leonard vs Al Brazle | Second | 5 out |
| » Major-league debuts: Willie Jones (Phillies) |
| Thursday, September 11 |
| » Lost to Dodgers (87-53), 4-3 | Sportsman's Park III (42-24) | 79-57 | |
| » Starters: Ralph Branca vs Harry Brecheen | Second | 6 out |
| Friday, September 12 |
| » Defeated Dodgers (87-54), 8-7 | Sportsman's Park III (43-24) | 80-57 | |
| » Starters: Hal Gregg vs Red Munger | Second | 5 out |
| Saturday, September 13 |
| » Lost to Dodgers (88-54), 8-7 | Sportsman's Park III (43-25) | 80-58 | |
| » Starters: Vic Lombardi vs Murry Dickson | Second | 6 out |
| Sunday, September 14 |
| » Lost to Giants (72-67), 9-1 | Sportsman's Park III (43-26) | 80-59 | Lost 2 |
| » Starters: Larry Jansen vs Jim Hearn | Second | 7½ out |
| Future Cardinal Harry Parker is born in Highland, IL. |
| Monday, September 15 |
| » Lost to Giants (73-67), 10-5 | Sportsman's Park III (43-27) | 80-60 | Lost 3 |
| » Starters: Dave Koslo vs Al Brazle | Second | 8 out |
| Tuesday, September 16 |
| » Lost to Giants (74-67), 7-2 | Sportsman's Park III (43-28) | 80-61 | Lost 4 |
| » Starters: Ray Poat vs Harry Brecheen | Second | 9 out |
| Wednesday, September 17 |
| » Lost to Braves (80-67), 10-8 | Sportsman's Park III (43-29) | 80-62 | Lost 5 |
| » Starters: Bill Voiselle vs Red Munger | Second | 10 out |
| Thursday, September 18 |
| » Lost to Braves (81-67), 6-2 | Sportsman's Park III (43-30) | 80-63 | Lost 6 |
| » Starters: Warren Spahn vs Murry Dickson | Second | 10 out |
| » Major-league debuts: Ken Johnson (Cardinals) |
| Friday, September 19 |
| » Defeated Cubs (66-80), 5-2 | Sportsman's Park III (44-30) | 81-63 | |
| » Starters: Johnny Schmitz vs Al Brazle | Second | 9½ out |
| Saturday, September 20 |
| » Defeated Cubs (66-81), 5-0 | Sportsman's Park III (45-30) | 82-63 | Won 2 |
| » Starters: Bob Chipman vs Red Munger | Second | 8½ out |
| Monday, September 22 |
| » Defeated Cubs (66-82), 4-2 | Sportsman's Park III (46-30) | 83-63 | Won 3 |
| » Starters: Ralph Hamner vs Harry Brecheen | Second | 8 out |
| » Lost to Cubs (67-82), 6-3 | Sportsman's Park III (46-31) | 83-64 | |
| » Starters: Paul Erickson vs Murry Dickson | Second | 8 out |
| Tuesday, September 23 |
| » Defeated Pirates (61-89), 8-4 | Forbes Field (5-3) | 84-64 | |
| » Starters: Jim Hearn vs Fritz Ostermueller | Second | 8 out |
| Wednesday, September 24 |
| » Defeated Pirates (61-90), 5-1 | Forbes Field (6-3) | 85-64 | Won 2 |
| » Starters: Red Munger vs Preacher Roe | Second | 7 out |
| Thursday, September 25 |
| » Defeated Pirates (61-91), 15-3 | Forbes Field (7-3) | 86-64 | Won 3 |
| » Starters: Murry Dickson vs Kirby Higbe | Second | 6½ out |
| » Defeated Pirates (61-92), 3-1 | Forbes Field (8-3) | 87-64 | Won 4 |
| » Starters: Gerry Staley vs Steve Nagy | Second | 6½ out |
| Friday, September 26 |
| » Defeated Cubs (68-84), 5-3 | Wrigley Field (5-4) | 88-64 | Won 5 |
| » Starters: Al Brazle vs Paul Erickson | Second | 6 out |
| Saturday, September 27 |
| » Defeated Cubs (68-85), 3-1 | Wrigley Field (6-4) | 89-64 | Won 6 |
| » Starters: Ken Johnson vs Ralph Hamner | Second | 5 out |
| Sunday, September 28 |
| » Lost to < |
