| Thursday, February 21 |
| Former Senator Bill Cunningham dies in Schenectady, NY at the age of 58. |
| Wednesday, March 6 |
| Former Senator Claude Thomas dies in Sulphur, OK at the age of 56. |
| Sunday, March 31 |
| Future Senator Bill Denehy is born in Middletown, CT. |
| Tuesday, April 16 |
| » Lost to Red Sox (1-0), 6-3 | Griffith Stadium (0-1) | 0-1 | |
| » Starters: Tex Hughson vs Roger Wolff | Second | 1 out |
| Wednesday, April 17 |
| » Lost to Red Sox (2-0), 13-6 | Griffith Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Dave Ferriss vs Walt Masterson | Third | 2 out |
| Thursday, April 18 |
| » Lost to Red Sox (3-0), 3-1 | Griffith Stadium (0-3) | 0-3 | Lost 3 |
| » Starters: Mickey Harris vs Ray Scarborough | Sixth | 3 out |
| Friday, April 19 |
| » Lost to Yankees (3-1), 7-6 | Yankee Stadium (0-1) | 0-4 | Lost 4 |
| » Starters: Mickey Haefner vs Joe Page | Seventh | 3½ out |
| Saturday, April 20 |
| » Defeated Yankees (3-2), 7-3 | Yankee Stadium (1-1) | 1-4 | |
| » Starters: Dutch Leonard vs Bill Wight | Seventh | 3½ out |
| Sunday, April 21 |
| » Lost to Yankees (4-2), 6-1 | Yankee Stadium (1-2) | 1-5 | |
| » Starters: Roger Wolff vs Spud Chandler | Eighth | 4 out |
| Monday, April 22 |
| » Lost to Red Sox (6-1), 5-4 | Fenway Park (0-1) | 1-6 | Lost 2 |
| » Starters: Sid Hudson vs Mickey Harris | Eighth | 5 out |
| » Major-league debuts: Eddie Pellagrini (Red Sox) |
| Tuesday, April 23 |
| » Defeated Red Sox (6-2), 8-2 | Fenway Park (1-1) | 2-6 | |
| » Starters: Walt Masterson vs Earl Johnson | Sixth | 4 out |
| Wednesday, April 24 |
| » Defeated Athletics (2-7), 4-2 | Griffith Stadium (1-3) | 3-6 | Won 2 |
| » Starters: Herman Besse vs Ray Scarborough | Sixth | 4 out |
| Friday, April 26 |
| » Lost to Yankees (8-3), 11-7 | Griffith Stadium (1-4) | 3-7 | |
| » Starters: Joe Page vs Sid Hudson | Fifth | 4½ out |
| Saturday, April 27 |
| » Lost to Yankees (9-3), 9-0 | Griffith Stadium (1-5) | 3-8 | Lost 2 |
| » Starters: Spud Chandler vs Walt Masterson | Seventh | 5½ out |
| » Major-league debuts: Gil Coan (Senators) |
| Sunday, April 28 |
| » Defeated Yankees (9-4), 3-1 | Griffith Stadium (2-5) | 4-8 | |
| » Starters: Al Gettel vs Roger Wolff | Seventh | 5½ out |
| Tuesday, April 30 |
| » Defeated White Sox (5-8), 3-2 | Griffith Stadium (3-5) | 5-8 | Won 2 |
| » Starters: Ed Lopat vs Ray Scarborough | Sixth | 5½ out |
| Friday, May 3 |
| » Lost to Browns (8-8), 5-1 | Griffith Stadium (3-6) | 5-9 | |
| » Starters: Sam Zoldak vs Roger Wolff | Seventh | 7½ out |
| Sunday, May 5 |
| » Defeated Indians (5-10), 12-4 | Griffith Stadium (4-6) | 6-9 | |
| » Starters: Allie Reynolds vs Dutch Leonard | Fifth | 7½ out |
| Monday, May 6 |
| » Defeated Indians (5-11), 7-4 | Griffith Stadium (5-6) | 7-9 | Won 2 |
| » Starters: Steve Gromek vs Ray Scarborough | Fifth | 8 out |
| Tuesday, May 7 |
| » Defeated Indians (5-12), 2-1 | Griffith Stadium (6-6) | 8-9 | Won 3 |
| » Starters: Red Embree vs Mickey Haefner | Fourth | 8 out |
| Wednesday, May 8 |
| » Lost to Tigers (11-10), 1-0 | Griffith Stadium (6-7) | 8-10 | |
| » Starters: Hal Newhouser vs Roger Wolff | Fourth | 9 out |
| Thursday, May 9 |
| » Lost to Tigers (12-10), 9-8 | Griffith Stadium (6-8) | 8-11 | Lost 2 |
| » Starters: Stubby Overmire vs Sid Hudson | Fifth | 10 out |
| Friday, May 10 |
| » Tied Athletics, 5-5 | Shibe Park (0-0) | 8-11 | |
| » Starters: Dutch Leonard vs Herman Besse | Fifth | 10½ out |
| Saturday, May 11 |
| » Defeated Athletics (6-17), 9-5 | Shibe Park (1-0) | 9-11 | |
| » Starters: Ray Scarborough vs Phil Marchildon | Fourth | 9½ out |
| Sunday, May 12 |
| » Lost to Athletics (7-17), 6-4 | Shibe Park (1-1) | 9-12 | |
| » Starters: Mickey Haefner vs Dick Fowler | Fourth | 10 out |
| » Defeated Athletics (7-18), 3-1 | Shibe Park (2-1) | 10-12 | |
| » Starters: Johnny Niggeling vs Bob Savage | Fourth | 10 out |
| Tuesday, May 14 |
| » Defeated Tigers (15-11), 15-1 | Tiger Stadium (1-0) | 11-12 | Won 2 |
| » Starters: Roger Wolff vs Stubby Overmire | Fourth | 10 out |
| Wednesday, May 15 |
| » Defeated Tigers (15-12), 6-3 | Tiger Stadium (2-0) | 12-12 | Won 3 |
| » Starters: Dutch Leonard vs Ted Gray | Fourth | 9 out |
| » Major-league debuts: Ted Gray (Tigers) |
| Friday, May 17 |
| » Lost to Indians (11-15), 3-0 | League Park II (0-1) | 12-13 | |
| » Starters: Mickey Haefner vs Bob Feller | Fourth | 8½ out |
| » Defeated Indians (11-16), 9-4 | League Park II (1-1) | 13-13 | |
| » Starters: Walt Masterson vs Joe Krakauskas | Fourth | 8½ out |
| Sunday, May 19 |
| » Defeated White Sox (9-17), 4-3 | Comiskey Park I (1-0) | 14-13 | Won 2 |
| » Starters: Roger Wolff vs Ted Lyons | Fourth | 8 out |
| » Defeated White Sox (9-18), 7-1 | Comiskey Park I (2-0) | 15-13 | Won 3 |
| » Starters: Johnny Niggeling vs Ed Lopat | Fourth | 8 out |
| Monday, May 20 |
| » Defeated White Sox (9-19), 10-2 | Comiskey Park I (3-0) | 16-13 | Won 4 |
| » Starters: Dutch Leonard vs Eddie Smith | Fourth | 7½ out |
| Wednesday, May 22 |
| » Lost to Browns (15-18), 3-1 | Sportsman's Park III (0-1) | 16-14 | |
| » Starters: Walt Masterson vs Tex Shirley | Fourth | 9 out |
| Saturday, May 25 |
| » Defeated Athletics (9-25), 4-1 | Griffith Stadium (7-8) | 17-14 | |
| » Starters: Bobo Newsom vs Mickey Haefner | Third | 8 out |
| » Defeated Athletics (9-26), 3-2 | Griffith Stadium (8-8) | 18-14 | Won 2 |
| » Starters: Dick Fowler vs Roger Wolff | Third | 8 out |
| Sunday, May 26 |
| » Defeated Athletics (9-27), 3-2 | Griffith Stadium (9-8) | 19-14 | Won 3 |
| » Starters: Lum Harris vs Johnny Niggeling | Third | 7½ out |
| Tuesday, May 28 |
| » Defeated Yankees (23-16), 2-1 | Yankee Stadium (2-2) | 20-14 | Won 4 |
| » Starters: Dutch Leonard vs Cuddles Marshall | Third | 7 out |
| Wednesday, May 29 |
| » Lost to Yankees (24-16), 4-0 | Yankee Stadium (2-3) | 20-15 | |
| » Starters: Mickey Haefner vs Red Ruffing | Third | 8 out |
| Thursday, May 30 |
| » Lost to Red Sox (31-9), 6-5 | Fenway Park (1-2) | 20-16 | Lost 2 |
| » Starters: Roger Wolff vs Tex Hughson | Third | 10 out |
| » Lost to Red Sox (32-9), 7-2 | Fenway Park (1-3) | 20-17 | Lost 3 |
| » Starters: Ray Scarborough vs Mickey Harris | Third | 10 out |
| Saturday, June 1 |
| » Defeated Tigers (22-20), 5-3 | Griffith Stadium (10-8) | 21-17 | |
| » Starters: Fred Hutchinson vs Walt Masterson | Third | 9½ out |
| Sunday, June 2 |
| » Lost to Tigers (23-20), 10-2 | Griffith Stadium (10-9) | 21-18 | |
| » Starters: Hal Newhouser vs Johnny Niggeling | Third | 10 out |
| Monday, June 3 |
| » Defeated Tigers (23-21), 7-4 | Griffith Stadium (11-9) | 22-18 | |
| » Starters: Stubby Overmire vs Dutch Leonard | Third | 10½ out |
| Tuesday, June 4 |
| » Lost to Indians (19-25), 10-2 | Griffith Stadium (11-10) | 22-19 | |
| » Starters: Bob Feller vs Mickey Haefner | Third | 11½ out |
| Wednesday, June 5 |
| » Defeated Indians (19-26), 5-1 | Griffith Stadium (12-10) | 23-19 | |
| » Starters: Steve Gromek vs Roger Wolff | Third | 11 out |
| Thursday, June 6 |
| » Defeated Indians (19-27), 4-0 | Griffith Stadium (13-10) | 24-19 | Won 2 |
| » Starters: Bob Lemon vs Sid Hudson | Third | 11 out |
| Friday, June 7 |
| » Defeated White Sox (15-27), 3-2 | Griffith Stadium (14-10) | 25-19 | Won 3 |
| » Starters: Eddie Smith vs Bobo Newsom | Third | 10½ out |
| Saturday, June 8 |
| » Defeated White Sox (15-28), 7-6 | Griffith Stadium (15-10) | 26-19 | Won 4 |
| » Starters: Thornton Lee vs Johnny Niggeling | Third | 10 out |
| » Defeated White Sox (15-29), 7-6 | Griffith Stadium (16-10) | 27-19 | Won 5 |
| » Starters: Orval Grove vs Bill Kennedy | Third | 10 out |
| Sunday, June 9 |
| » Defeated White Sox (15-30), 7-1 | Griffith Stadium (17-10) | 28-19 | Won 6 |
| » Starters: Joe Haynes vs Mickey Haefner | Third | 11 out |
| » Lost to White Sox (16-30), 8-1 | Griffith Stadium (17-11) | 28-20 | |
| » Starters: Ed Lopat vs Dutch Leonard | Third | 11 out |
| Monday, June 10 |
| » Lost to Browns (20-29), 2-1 | Griffith Stadium (17-12) | 28-21 | Lost 2 |
| » Starters: Sam Zoldak vs Roger Wolff | Third | 12 out |
| Tuesday, June 11 |
| » Lost to Browns (21-29), 6-2 | Griffith Stadium (17-13) | 28-22 | Lost 3 |
| » Starters: Tex Shirley vs Sid Hudson | Third | 13 out |
| Wednesday, June 12 |
| » Lost to Browns (22-29), 1-0 | Griffith Stadium (17-14) | 28-23 | Lost 4 |
| » Starters: Jack Kramer vs Bobo Newsom | Third | 13 out |
| Friday, June 14 |
| » Lost to Tigers (29-24), 6-2 | Tiger Stadium (2-1) | 28-24 | Lost 5 |
| » Starters: Mickey Haefner vs Virgil Trucks | Fourth | 13 out |
| Saturday, June 15 |
| » Lost to Tigers (30-24), 3-1 | Tiger Stadium (2-2) | 28-25 | Lost 6 |
| » Starters: Dutch Leonard vs Hal Newhouser | Fourth | 13 out |
| Sunday, June 16 |
| » Defeated Tigers (30-25), 6-3 | Tiger Stadium (3-2) | 29-25 | |
| » Starters: Roger Wolff vs Fred Hutchinson | Fourth | 12½ out |
| Thursday, June 20 |
| » Lost to Indians (26-32), 4-3 | Cleveland Stadium (0-1) | 29-26 | |
| » Starters: Bobo Newsom vs Allie Reynolds | Fourth | 11½ out |
| Friday, June 21 |
| » Defeated Browns (26-33), 4-2 | Sportsman's Park III (1-1) | 30-26 | |
| » Starters: Dutch Leonard vs Denny Galehouse | Fourth | 11½ out |
| Saturday, June 22 |
| » Lost to Browns (27-33), 14-8 | Sportsman's Park III (1-2) | 30-27 | |
| » Starters: Johnny Niggeling vs Tex Shirley | Fourth | 11½ out |
| Sunday, June 23 |
| » Defeated Browns (27-34), 7-4 | Sportsman's Park III (2-2) | 31-27 | |
| » Starters: Mickey Haefner vs Jack Kramer | Fourth | 12½ out |
| » Lost to Browns (28-34), 7-4 | Sportsman's Park III (2-3) | 31-28 | |
| » Starters: Sid Hudson vs Bob Muncrief | Fourth | 12½ out |
| Monday, June 24 |
| » Lost to White Sox (24-35), 12-7 | Comiskey Park I (3-1) | 31-29 | Lost 2 |
| » Starters: Walt Masterson vs Eddie Smith | Fourth | 13 out |
| Tuesday, June 25 |
| » Lost to White Sox (25-35), 6-4 | Comiskey Park I (3-2) | 31-30 | Lost 3 |
| » Starters: Bobo Newsom vs Bill Dietrich | Fourth | 14 out |
| Wednesday, June 26 |
| » Defeated White Sox (25-36), 4-3 | Comiskey Park I (4-2) | 32-30 | |
| » Starters: Dutch Leonard vs Joe Haynes | Fourth | 13½ out |
| Friday, June 28 |
| » Lost to Red Sox (48-18), 12-1 | Fenway Park (1-4) | 32-31 | |
| » Starters: Roger Wolff vs Mickey Harris | Fourth | 14½ out |
| Saturday, June 29 |
| » Lost to Red Sox (49-18), 12-8 | Fenway Park (1-5) | 32-32 | Lost 2 |
| » Starters: Walt Masterson vs Tex Hughson | Fourth | 15½ out |
| Sunday, June 30 |
| » Lost to Red Sox (50-18), 15-8 | Fenway Park (1-6) | 32-33 | Lost 3 |
| » Starters: Bobo Newsom vs Dave Ferriss | Fourth | 15½ out |
| » Defeated Red Sox (50-19), 9-2 | Fenway Park (2-6) | 33-33 | |
| » Starters: Mickey Haefner vs Earl Johnson | Fourth | 15½ out |
| Wednesday, July 3 |
| » Defeated Athletics (20-47), 3-1 | Shibe Park (3-1) | 34-33 | Won 2 |
| » Starters: Sid Hudson vs Lum Harris | Fourth | 14 out |
| Thursday, July 4 |
| » Defeated Yankees (44-29), 2-0 | Griffith Stadium (18-14) | 35-33 | Won 3 |
| » Starters: Jake Wade vs Dutch Leonard | Fourth | 14 out |
| » Lost to Yankees (45-29), 5-0 | Griffith Stadium (18-15) | 35-34 | |
| » Starters: Joe Page vs Roger Wolff | Fourth | 14 out |
| Friday, July 5 |
| » Defeated Yankees (45-30), 6-1 | Griffith Stadium (19-15) | 36-34 | |
| » Starters: Mel Queen vs Bobo Newsom | Fourth | 14 out |
| Saturday, July 6 |
| » Defeated Red Sox (52-23), 4-0 | Griffith Stadium (20-15) | 37-34 | Won 2 |
| » Starters: Mickey Harris vs Mickey Haefner | Fourth | 13 out |
| Sunday, July 7 |
| » Lost to Red Sox (53-23), 11-1 | Griffith Stadium (20-16) | 37-35 | |
| » Starters: Tex Hughson vs Sid Hudson | Fourth | 15 out |
| » Lost to Red Sox (54-23), 9-4 | Griffith Stadium (20-17) | 37-36 | Lost 2 |
| » Starters: Clem Dreisewerd vs Walt Masterson | Fourth | 15 out |
| Thursday, July 11 |
| » Lost to White Sox (30-44), 4-2 | Griffith Stadium (20-18) | 37-37 | Lost 3 |
| » Starters: Eddie Smith vs Mickey Haefner | Fourth | 16 out |
| Saturday, July 13 |
| » Defeated White Sox (30-45), 6-5 | Griffith Stadium (21-18) | 38-37 | |
| » Starters: Ed Lopat vs Bobo Newsom | Fourth | 17 out |
| » Lost to White Sox (31-45), 9-2 | Griffith Stadium (21-19) | 38-38 | |
| » Starters: Frank Papish vs Dutch Leonard | Fourth | 17 out |
| Sunday, July 14 |
| » Defeated Browns (36-43), 5-3 | Griffith Stadium (22-19) | 39-38 | |
| » Starters: Sam Zoldak vs Sid Hudson | Fourth | 17 out |
| » Defeated Browns (36-44), 4-2 | Griffith Stadium (23-19) | 40-38 | Won 2 |
| » Starters: Bob Muncrief vs Ray Scarborough | Fourth | 17 out |
| Monday, July 15 |
| » Defeated Browns (36-45), 4-2 | Griffith Stadium (24-19) | 41-38 | Won 3 |
| » Starters: Tex Shirley vs Mickey Haefner | Fourth | 16½ out |
| Tuesday, July 16 |
| » Lost to Browns (37-45), 7-1 | Griffith Stadium (24-20) | 41-39 | |
| » Starters: Jack Kramer vs Bill Kennedy | Fourth | 16½ out |
| Wednesday, July 17 |
| » Lost to Tigers (46-35), 3-2 | Griffith Stadium (24-21) | 41-40 | Lost 2 |
| » Starters: Virgil Trucks vs Bobo Newsom | Fourth | 18 out |
| Thursday, July 18 |
| » Defeated Tigers (46-36), 1-0 | Griffith Stadium (25-21) | 42-40 | |
| » Starters: Dizzy Trout vs Dutch Leonard | Fourth | 18 out |
| Friday, July 19 |
| » Lost to Tigers (47-36), 10-5 | Griffith Stadium (25-22) | 42-41 | |
| » Starters: Hal Newhouser vs Ray Scarborough | Fourth | 19 out |
| Saturday, July 20 |
| » Lost to Indians (41-45), 10-2 | Griffith Stadium (25-23) | 42-42 | Lost 2 |
| » Starters: Bob Feller vs Sid Hudson | Fourth | 19 out |
| Sunday, July 21 |
| » Defeated Indians (41-46), 2-1 | Griffith Stadium (26-23) | 43-42 | |
| » Starters: Charlie Gassaway vs Mickey Haefner | Fourth | 19 out |
| » Defeated Indians (41-47), 7-5 | Griffith Stadium (27-23) | 44-42 | Won 2 |
| » Starters: Red Embree vs Early Wynn | Fourth | 19 out |
| Tuesday, July 23 |
| » Lost to Tigers (50-37), 6-1 | Tiger Stadium (3-3) | 44-43 | |
| » Starters: Dutch Leonard vs Hal Newhouser | Fourth | 19 out |
| Wednesday, July 24 |
| » Defeated Tigers (50-38), 1-0 | Tiger Stadium (4-3) | 45-43 | |
| » Starters: Bobo Newsom vs Dizzy Trout | Fourth | 19 out |
| Thursday, July 25 |
| » Defeated Tigers (50-39), 8-3 | Tiger Stadium (5-3) | 46-43 | Won 2 |
| » Starters: Ray Scarborough vs Fred Hutchinson | Fourth | 18 out |
| Friday, July 26 |
| » Defeated Indians (44-48), 5-4 | Cleveland Stadium (1-1) | 47-43 | Won 3 |
| » Starters: Mickey Haefner vs Steve Gromek | Fourth | 18 out |
| Saturday, July 27 |
| » Defeated Indians (44-49), 3-2 | League Park II (2-1) | 48-43 | Won 4 |
| » Starters: Sid Hudson vs Red Embree | Fourth | 18 out |
| Sunday, July 28 |
| » Lost to Indians (45-49), 2-0 | Cleveland Stadium (1-2) | 48-44 | |
| » Starters: Bobo Newsom vs Bob Feller | Fourth | 19 out |
| » Lost to Indians (46-49), 7-4 | Cleveland Stadium (1-3) | 48-45 | Lost 2 |
| » Starters: Dutch Leonard vs Allie Reynolds | Fourth | 19 out |
| Monday, July 29 |
| » Defeated Indians (46-50), 2-1 | League Park II (3-1) | 49-45 | |
| » Starters: Ray Scarborough vs Charlie Gassaway | Fourth | 18 out |
| » Defeated Indians (46-51), 8-4 | League Park II (4-1) | 50-45 | Won 2 |
| » Starters: Early Wynn vs Joe Krakauskas | Fourth | 18 out |
| Tuesday, July 30 |
| » Lost to Browns (41-54), 6-3 | Sportsman's Park III (2-4) | 50-46 | |
| » Starters: Mickey Haefner vs Stan Ferens | Fourth | 19 out |
| Wednesday, July 31 |
| » Lost to Browns (42-54), 6-2 | Sportsman's Park III (2-5) | 50-47 | Lost 2 |
| » Starters: Sid Hudson vs Nels Potter | Fourth | 19 out |
| Thursday, August 1 |
| » Lost to Browns (43-54), 8-2 | Sportsman's Park III (2-6) | 50-48 | Lost 3 |
| » Starters: Dutch Leonard vs Jack Kramer | Fourth | 19 out |
| Friday, August 2 |
| » Defeated White Sox (40-59), 6-0 | Comiskey Park I (5-2) | 51-48 | |
| » Starters: Bobo Newsom vs Johnny Rigney | Fourth | 18 out |
| Saturday, August 3 |
| » Lost to White Sox (41-59), 1-0 | Comiskey Park I (5-3) | 51-49 | |
| » Starters: Ray Scarborough vs Orval Grove | Fourth | 19 out |
| Sunday, August 4 |
| » Lost to White Sox (42-59), 3-1 | Comiskey Park I (5-4) | 51-50 | Lost 2 |
| » Starters: Mickey Haefner vs Eddie Smith | Fourth | 20½ out |
| » Lost to White Sox (43-59), 1-0 | Comiskey Park I (5-5) | 51-51 | Lost 3 |
| » Starters: Early Wynn vs Frank Papish | Fourth | 20½ out |
| Wednesday, August 7 |
| » Defeated Yankees (59-43), 4-3 | Griffith Stadium (28-23) | 52-51 | |
| » Starters: Spud Chandler vs Bobo Newsom | Fourth | 20½ out |
| Thursday, August 8 |
| » Lost to Yankees (60-43), 9-3 | Griffith Stadium (28-24) | 52-52 | |
| » Starters: Bill Wight vs Dutch Leonard | Fourth | 22½ out |
| » Lost to Yankees (61-43), 13-1 | Griffith Stadium (28-25) | 52-53 | Lost 2 |
| » Starters: Randy Gumpert vs Ray Scarborough | Fourth | 22½ out |
| Friday, August 9 |
| » Defeated Athletics (30-75), 2-1 | Griffith Stadium (29-25) | 53-53 | |
| » Starters: Lum Harris vs Mickey Haefner | Fourth | 22½ out |
| Saturday, August 10 |
| » Defeated Athletics (30-76), 4-1 | Griffith Stadium (30-25) | 54-53 | Won 2 |
| » Starters: Dick Fowler vs Early Wynn | Fourth | 22 out |
| » Lost to Athletics (31-76), 8-3 | Griffith Stadium (30-26) | 54-54 | |
| » Starters: Jesse Flores vs Sid Hudson | Fourth | 22 out |
| Sunday, August 11 |
| » Defeated Athletics (31-77), 3-1 | Griffith Stadium (31-26) | 55-54 | |
| » Starters: Lou Knerr vs Bobo Newsom | Fourth | 22 out |
| » Lost to Athletics (32-77), 12-5 | Griffith Stadium (31-27) | 55-55 | |
| » Starters: Phil Marchildon vs Ray Scarborough | Fourth | 22 out |
| Wednesday, August 14 |
| » Lost to Yankees (64-45), 4-1 | Yankee Stadium (2-4) | 55-56 | Lost 2 |
| » Starters: Dutch Leonard vs Bill Bevens | Fourth | 23½ out |
| Thursday, August 15 |
| » Lost to Yankees (65-45), 6-1 | Yankee Stadium (2-5) | 55-57 | Lost 3 |
| » Starters: Mickey Haefner vs Bill Wight | Fourth | 24 out |
| » Lost to Yankees (66-45), 7-2 | Yankee Stadium (2-6) | 55-58 | Lost 4 |
| » Starters: Early Wynn vs Randy Gumpert | Fourth | 24 out |
| Saturday, August 17 |
| » Defeated Athletics (33-80), 12-7 | Shibe Park (4-1) | 56-58 | |
| » Starters: Bobo Newsom vs Lum Harris | Fourth | 25 out |
| » Lost to Athletics (34-80), 5-3 | Shibe Park (4-2) | 56-59 | |
| » Starters: Ray Scarborough vs Phil Marchildon | Fourth | 25 out |
| Sunday, August 18 |
| » Lost to Athletics (35-80), 11-0 | Shibe Park (4-3) | 56-60 | Lost 2 |
| » Starters: Dutch Leonard vs Jesse Flores | Fourth | 25 out |
| » Defeated Athletics (35-81), 6-4 | Shibe Park (5-3) | 57-60 | |
| » Starters: Roger Wolff vs Dick Fowler | Fourth | 25 out |
| Tuesday, August 20 |
| » Defeated Indians (56-62), 5-4 | Griffith Stadium (32-27) | 58-60 | Won 2 |
| » Starters: Bob Feller vs Mickey Haefner | Fourth | 24½ out |
| Wednesday, August 21 |
| » Defeated Indians (56-63), 4-3 | Griffith Stadium (33-27) | 59-60 | Won 3 |
| » Starters: Charlie Gassaway vs Early Wynn | Fourth | 24½ out |
| Friday, August 23 |
| » Defeated Tigers (64-52), 3-2 | Griffith Stadium (34-27) | 60-60 | Won 4 |
| » Starters: Fred Hutchinson vs Bobo Newsom | Fourth | 24 out |
| » Lost to Tigers (65-52), 5-0 | Griffith Stadium (34-28) | 60-61 | |
| » Starters: Dizzy Trout vs Ray Scarborough | Fourth | 24 out |
| Saturday, August 24 |
| » Lost to Tigers (66-52), 8-4 | Griffith Stadium (34-29) | 60-62 | Lost 2 |
| » Starters: Al Benton vs Dutch Leonard | Fourth | 24½ out |
| Sunday, August 25 |
| » Defeated Browns (51-70), 5-4 | Griffith Stadium (35-29) | 61-62 | |
| » Starters: Tex Shirley vs Mickey Haefner | Fourth | 25 out |
| Monday, August 26 |
| » Defeated Browns (51-71), 5-2 | Griffith Stadium (36-29) | 62-62 | Won 2 |
| » Starters: Bob Muncrief vs Early Wynn | Fourth | 25 out |
| Tuesday, August 27 |
| » Lost to Browns (52-71), 4-2 | Griffith Stadium (36-30) | 62-63 | |
| » Starters: Sam Zoldak vs Sid Hudson | Fourth | 25½ out |
| Wednesday, August 28 |
| » Lost to White Sox (57-70), 2-1 | Griffith Stadium (36-31) | 62-64 | Lost 2 |
| » Starters: Orval Grove vs Bobo Newsom | Fourth | 25½ out |
| Saturday, August 31 |
| » Lost to Yankees (76-52), 4-0 | Griffith Stadium (36-32) | 62-65 | Lost 3 |
| » Starters: Bill Bevens vs Ray Scarborough | Fourth | 27 out |
| Sunday, September 1 |
| » Lost to Yankees (77-52), 7-2 | Griffith Stadium (36-33) | 62-66 | Lost 4 |
| » Starters: Spud Chandler vs Mickey Haefner | Fourth | 28 out |
| Monday, September 2 |
| » Defeated Athletics (42-89), 5-2 | Griffith Stadium (37-33) | 63-66 | |
| » Starters: Lum Harris vs Bobo Newsom | Fourth | 29 out |
| » Lost to Athletics (43-89), 7-1 | Griffith Stadium (37-34) | 63-67 | |
| » Starters: Jesse Flores vs Early Wynn | Fourth | 29 out |
| Wednesday, September 4 |
| » Lost to Red Sox (95-40), 4-2 | Griffith Stadium (37-35) | 63-68 | Lost 2 |
| » Starters: Tex Hughson vs Sid Hudson | Fourth | 30 out |
| Thursday, September 5 |
| » Lost to Red Sox (96-40), 1-0 | Griffith Stadium (37-36) | 63-69 | Lost 3 |
| » Starters: Jim Bagby vs Ray Scarborough | Fourth | 31 out |
| Friday, September 6 |
| » Defeated Red Sox (96-41), 3-2 | Griffith Stadium (38-36) | 64-69 | |
| » Starters: Mickey Harris vs Bobo Newsom | Fourth | 30 out |
| Saturday, September 7 |
| » Lost to Yankees (79-56), 7-4 | Yankee Stadium (2-7) | 64-70 | |
| » Starters: Mickey Haefner vs Joe Page | Fourth | 30 out |
| Sunday, September 8 |
| » Defeated Yankees (79-57), 2-1 | Yankee Stadium (3-7) | 65-70 | |
| » Starters: Early Wynn vs Bill Bevens | Fourth | 28½ out |
| » Defeated Yankees (79-58), 9-8 | Yankee Stadium (4-7) | 66-70 | Won 2 |
| » Starters: Dutch Leonard vs Karl Drews | Fourth | 28½ out |
| » Major-league debuts: Karl Drews (Yankees) |
| Monday, September 9 |
| » Major-league debuts: Sheldon Jones (Giants) |
| Tuesday, September 10 |
| » Defeated White Sox (63-75), 4-2 | Comiskey Park I (6-5) | 67-70 | Won 3 |
| » Starters: Marino Pieretti vs Eddie Smith | Fourth | 27½ out |
| Wednesday, September 11 |
| » Lost to White Sox (64-75), 6-1 | Comiskey Park I (6-6) | 67-71 | |
| » Starters: Bobo Newsom vs Joe Haynes | Fourth | 27½ out |
| Thursday, September 12 |
| » Defeated Browns (59-77), 9-6 | Sportsman's Park III (3-6) | 68-71 | |
| » Starters: Mickey Haefner vs Chet Johnson | Fourth | 26½ out |
| » Major-league debuts: Chet Johnson (Browns) |
| Friday, September 13 |
| » Lost to Browns (60-77), 7-0 | Sportsman's Park III (3-7) | 68-72 | |
| » Starters: Early Wynn vs Jack Kramer | Fourth | 27½ out |
| Saturday, September 14 |
| » Defeated Browns (60-78), 3-1 | Sportsman's Park III (4-7) | 69-72 | |
| » Starters: Ray Scarborough vs Sam Zoldak | Fourth | 27 out |
| Sunday, September 15 |
| » Defeated Tigers (80-59), 15-5 | Tiger Stadium (6-3) | 70-72 | Won 2 |
| » Starters: Roger Wolff vs Dizzy Trout | Fourth | 26½ out |
| Monday, September 16 |
| » Lost to Tigers (81-59), 11-7 | Tiger Stadium (6-4) | 70-73 | |
| » Starters: Bobo Newsom vs Stubby Overmire | Fourth | 27 out |
| Tuesday, September 17 |
| » Lost to Tigers (82-59), 6-4 | Tiger Stadium (6-5) | 70-74 | Lost 2 |
| » Starters: Marino Pieretti vs Al Benton | Fourth | 27½ out |
| Wednesday, September 18 |
| » Defeated Indians (65-80), 8-1 | League Park II (5-1) | 71-74 | |
| » Starters: Mickey Haefner vs Ralph McCabe | Fourth | 27½ out |
| Thursday, September 19 |
| » Lost to Indians (66-80), 5-1 | League Park II (5-2) | 71-75 | |
| » Starters: Ray Scarborough vs Bob Feller | Fourth | 27½ out |
| Saturday, September 21 |
| » Lost to Red Sox (100-48), 7-5 | Griffith Stadium (38-37) | 71-76 | Lost 2 |
| » Starters: Dave Ferriss vs Bobo Newsom | Fourth | 28½ out |
| Sunday, September 22 |
| » Lost to Red Sox (101-48), 4-1 | Griffith Stadium (38-38) | 71-77 | Lost 3 |
| » Starters: Tex Hughson vs Early Wynn | Fourth | 29½ out |
| Monday, September 23 |
| » Major-league debuts: Vic Raschi (Yankees) |
| Wednesday, September 25 |
| » Defeated Athletics (49-101), 6-3 | Shibe Park (6-3) | 72-77 | |
| » Starters: Roger Wolff vs Lum Harris | Fourth | 29½ out |
| » Defeated Athletics (49-102), 7-4 | Shibe Park (7-3) | 73-77 | Won 2 |
| » Starters: Dutch Leonard vs Lou Knerr | Fourth | 29½ out |
| Thursday, September 26 |
| » Defeated Athletics (49-103), 2-0 | Shibe Park (8-3) | 74-77 | Won 3 |
| » Starters: Mickey Haefner vs Jesse Flores | Fourth | 29 out |
| Friday, September 27 |
| » Lost to Red Sox (104-48), 5-4 | Fenway Park (2-7) | 74-78 | |
| » Starters: Bobo Newsom vs Tex Hughson | Fourth | 30 out |
| Saturday, September 28 |
| » Defeated Red Sox (104-49), 4-3 | Fenway Park (3-7) | 75-78 | |
| » Starters: Early Wynn vs Dave Ferriss | Fourth | 29 out |
| Sunday, September 29 |
| » Defeated Red Sox (104-50), 7-0 | Fenway Park (4-7) | 76-78 | Won 2 |
| » Starters: Ray Scarborough vs Joe Dobson | Fourth | 28 out |
| Tuesday, December 10 |
| Former Senator Walter Johnson dies in Washington, DC at the age of 60. |
Game information provided by Retrosheet (www.retrosheet.org) |