| Monday, April 8 |
| Future Athletic Catfish Hunter is born in Hertford, NC. |
| Tuesday, April 16 |
| » Lost to Yankees (1-0), 5-0 | Shibe Park (0-1) | 0-1 | |
| » Starters: Spud Chandler vs Russ Christopher | Second | 1 out |
| » Major-league debuts: Gene Handley (Athletics) |
| Wednesday, April 17 |
| » Defeated Yankees (1-1), 7-1 | Shibe Park (1-1) | 1-1 | |
| » Starters: Randy Gumpert vs Bobo Newsom | Second | 1 out |
| » Major-league debuts: Bill Wight (Yankees) |
| Thursday, April 18 |
| » Lost to Yankees (2-1), 8-1 | Shibe Park (1-2) | 1-2 | |
| » Starters: Al Gettel vs Jesse Flores | Fourth | 2 out |
| Saturday, April 20 |
| » Lost to Red Sox (4-0), 2-1 | Fenway Park (0-1) | 1-3 | Lost 2 |
| » Starters: Dick Fowler vs Tex Hughson | Sixth | 3 out |
| Sunday, April 21 |
| » Lost to Red Sox (5-0), 12-11 | Fenway Park (0-2) | 1-4 | Lost 3 |
| » Starters: Russ Christopher vs Dave Ferriss | Sixth | 3 out |
| » Defeated Red Sox (5-1), 3-0 | Fenway Park (1-2) | 2-4 | |
| » Starters: Bobo Newsom vs Jim Bagby | Sixth | 3 out |
| » Major-league debuts: Mel Deutsch (Red Sox) |
| Monday, April 22 |
| » Lost to Yankees (5-2), 2-1 | Yankee Stadium (0-1) | 2-5 | |
| » Starters: Lou Knerr vs Bill Bevens | Sixth | 4 out |
| Tuesday, April 23 |
| » Lost to Yankees (6-2), 3-0 | Yankee Stadium (0-2) | 2-6 | Lost 2 |
| » Starters: Lum Harris vs Al Gettel | Sixth | 4 out |
| Wednesday, April 24 |
| » Lost to Senators (3-6), 4-2 | Griffith Stadium (0-1) | 2-7 | Lost 3 |
| » Starters: Herman Besse vs Ray Scarborough | Eighth | 5 out |
| Friday, April 26 |
| » Lost to Red Sox (8-3), 7-0 | Shibe Park (1-3) | 2-8 | Lost 4 |
| » Starters: Dave Ferriss vs Dick Fowler | Sixth | 5½ out |
| Sunday, April 28 |
| » Lost to Red Sox (9-3), 2-1 | Shibe Park (1-4) | 2-9 | Lost 5 |
| » Starters: Tex Hughson vs Lou Knerr | Eighth | 7½ out |
| » Lost to Red Sox (10-3), 5-1 | Shibe Park (1-5) | 2-10 | Lost 6 |
| » Starters: Mickey Harris vs Bobo Newsom | Eighth | 7½ out |
| Tuesday, April 30 |
| » Defeated Browns (6-7), 12-8 | Shibe Park (2-5) | 3-10 | |
| » Starters: Tex Shirley vs Russ Christopher | Seventh | 7½ out |
| » Major-league debuts: Ellis Kinder (Browns) |
| Wednesday, May 1 |
| » Defeated Browns (6-8), 3-2 | Shibe Park (3-5) | 4-10 | Won 2 |
| » Starters: Nels Potter vs Dick Fowler | Seventh | 7½ out |
| Thursday, May 2 |
| » Lost to Browns (7-8), 10-3 | Shibe Park (3-6) | 4-11 | |
| » Starters: Jack Kramer vs Herman Besse | Seventh | 8½ out |
| Friday, May 3 |
| » Lost to White Sox (6-8), 8-5 | Shibe Park (3-7) | 4-12 | Lost 2 |
| » Starters: Bill Dietrich vs Lou Knerr | Eighth | 9½ out |
| Sunday, May 5 |
| » Defeated Tigers (7-10), 10-2 | Shibe Park (4-7) | 5-12 | |
| » Starters: Al Benton vs Bobo Newsom | Seventh | 10 out |
| » Lost to Tigers (8-10), 5-4 | Shibe Park (4-8) | 5-13 | |
| » Starters: Tommy Bridges vs Russ Christopher | Seventh | 10 out |
| Monday, May 6 |
| » Lost to Tigers (9-10), 3-1 | Shibe Park (4-9) | 5-14 | Lost 2 |
| » Starters: Virgil Trucks vs Phil Marchildon | Seventh | 11½ out |
| Tuesday, May 7 |
| » Lost to Tigers (10-10), 7-2 | Shibe Park (4-10) | 5-15 | Lost 3 |
| » Starters: Dizzy Trout vs Dick Fowler | Eighth | 12½ out |
| Wednesday, May 8 |
| » Lost to Indians (6-12), 5-2 | Shibe Park (4-11) | 5-16 | Lost 4 |
| » Starters: Bob Feller vs Lou Knerr | Eighth | 13½ out |
| Thursday, May 9 |
| » Defeated Indians (6-13), 7-6 | Shibe Park (5-11) | 6-16 | |
| » Starters: Don Black vs Bobo Newsom | Eighth | 13½ out |
| Friday, May 10 |
| » Tied Senators, 5-5 | Shibe Park (5-11) | 6-16 | |
| » Starters: Dutch Leonard vs Herman Besse | Eighth | 14 out |
| Saturday, May 11 |
| » Lost to Senators (9-11), 9-5 | Shibe Park (5-12) | 6-17 | |
| » Starters: Ray Scarborough vs Phil Marchildon | Eighth | 14 out |
| Sunday, May 12 |
| » Defeated Senators (9-12), 6-4 | Shibe Park (6-12) | 7-17 | |
| » Starters: Mickey Haefner vs Dick Fowler | Eighth | 14½ out |
| » Lost to Senators (10-12), 3-1 | Shibe Park (6-13) | 7-18 | |
| » Starters: Johnny Niggeling vs Bob Savage | Eighth | 14½ out |
| Wednesday, May 15 |
| » Lost to Indians (9-15), 3-0 | League Park II (0-1) | 7-19 | Lost 2 |
| » Starters: Jack Knott vs Mel Harder | Eighth | 15½ out |
| » Lost to Indians (10-15), 5-0 | League Park II (0-2) | 7-20 | Lost 3 |
| » Starters: Bobo Newsom vs Steve Gromek | Eighth | 15½ out |
| Friday, May 17 |
| » Lost to Tigers (16-12), 3-1 | Tiger Stadium (0-1) | 7-21 | Lost 4 |
| » Starters: Phil Marchildon vs Virgil Trucks | Eighth | 15½ out |
| Saturday, May 18 |
| » Lost to Tigers (17-12), 2-0 | Tiger Stadium (0-2) | 7-22 | Lost 5 |
| » Starters: Bobo Newsom vs Fred Hutchinson | Eighth | 16½ out |
| Future Athletic Reggie Jackson is born in Wyncote, PA. |
| Sunday, May 19 |
| » Defeated Browns (13-17), 4-3 | Sportsman's Park III (1-0) | 8-22 | |
| » Starters: Dick Fowler vs Sam Zoldak | Eighth | 15½ out |
| » Defeated Browns (13-18), 13-2 | Sportsman's Park III (2-0) | 9-22 | Won 2 |
| » Starters: Lou Knerr vs Al Milnar | Eighth | 15½ out |
| Tuesday, May 21 |
| » Lost to Browns (14-18), 4-3 | Sportsman's Park III (2-1) | 9-23 | |
| » Starters: Bob Savage vs Jack Kramer | Eighth | 16½ out |
| Wednesday, May 22 |
| » Lost to White Sox (10-19), 5-4 | Comiskey Park I (0-1) | 9-24 | Lost 2 |
| » Starters: Phil Marchildon vs Joe Haynes | Eighth | 17½ out |
| Saturday, May 25 |
| » Lost to Senators (17-14), 4-1 | Griffith Stadium (0-2) | 9-25 | Lost 3 |
| » Starters: Bobo Newsom vs Mickey Haefner | Seventh | 18½ out |
| » Lost to Senators (18-14), 3-2 | Griffith Stadium (0-3) | 9-26 | Lost 4 |
| » Starters: Dick Fowler vs Roger Wolff | Seventh | 18½ out |
| Sunday, May 26 |
| » Lost to Senators (19-14), 3-2 | Griffith Stadium (0-4) | 9-27 | Lost 5 |
| » Starters: Lum Harris vs Johnny Niggeling | Seventh | 19 out |
| Wednesday, May 29 |
| » Lost to Red Sox (30-9), 2-0 | Fenway Park (1-3) | 9-28 | Lost 6 |
| » Starters: Phil Marchildon vs Dave Ferriss | Seventh | 20 out |
| Thursday, May 30 |
| » Lost to Yankees (25-16), 6-1 | Yankee Stadium (0-3) | 9-29 | Lost 7 |
| » Starters: Lou Knerr vs Spud Chandler | Seventh | 22 out |
| » Lost to Yankees (26-16), 6-3 | Yankee Stadium (0-4) | 9-30 | Lost 8 |
| » Starters: Bobo Newsom vs Bill Bevens | Seventh | 22 out |
| Friday, May 31 |
| » Lost to Yankees (27-16), 8-1 | Yankee Stadium (0-5) | 9-31 | Lost 9 |
| » Starters: Dick Fowler vs Joe Page | Seventh | 22½ out |
| Saturday, June 1 |
| » Defeated Indians (17-24), 10-4 | Shibe Park (7-13) | 10-31 | |
| » Starters: Joe Krakauskas vs Russ Christopher | Eighth | 22 out |
| Monday, June 3 |
| » Lost to Indians (18-24), 6-5 | Shibe Park (7-14) | 10-32 | |
| » Starters: Red Embree vs Phil Marchildon | Eighth | 23 out |
| » Defeated Indians (18-25), 3-2 | Shibe Park (8-14) | 11-32 | |
| » Starters: Bob Lemon vs Dick Fowler | Eighth | 23 out |
| Tuesday, June 4 |
| » Lost to Tigers (24-21), 2-0 | Shibe Park (8-15) | 11-33 | |
| » Starters: Dizzy Trout vs Lou Knerr | Eighth | 24 out |
| Wednesday, June 5 |
| » Lost to Tigers (25-21), 2-0 | Shibe Park (8-16) | 11-34 | Lost 2 |
| » Starters: Virgil Trucks vs Jesse Flores | Eighth | 24½ out |
| Friday, June 7 |
| » Defeated Browns (18-27), 5-4 | Shibe Park (9-16) | 12-34 | |
| » Starters: Bob Muncrief vs Russ Christopher | Eighth | 24½ out |
| Saturday, June 8 |
| » Defeated Browns (18-28), 9-3 | Shibe Park (10-16) | 13-34 | Won 2 |
| » Starters: Ellis Kinder vs Dick Fowler | Eighth | 24½ out |
| Sunday, June 9 |
| » Lost to Browns (19-28), 6-2 | Shibe Park (10-17) | 13-35 | |
| » Starters: Denny Galehouse vs Bob Savage | Eighth | 25½ out |
| » Defeated Browns (19-29), 8-4 | Shibe Park (11-17) | 14-35 | |
| » Starters: Nels Potter vs Phil Marchildon | Eighth | 25½ out |
| Monday, June 10 |
| » Lost to White Sox (17-30), 3-1 | Shibe Park (11-18) | 14-36 | |
| » Starters: Bill Dietrich vs Jesse Flores | Eighth | 26½ out |
| Tuesday, June 11 |
| » Lost to White Sox (18-30), 1-0 | Shibe Park (11-19) | 14-37 | Lost 2 |
| » Starters: Eddie Smith vs Russ Christopher | Eighth | 27½ out |
| Friday, June 14 |
| » Defeated Indians (22-32), 5-3 | Cleveland Stadium (1-0) | 15-37 | |
| » Starters: Dick Fowler vs Allie Reynolds | Eighth | 26 out |
| Saturday, June 15 |
| » Lost to Indians (23-32), 4-1 | League Park II (0-3) | 15-38 | |
| » Starters: Phil Marchildon vs Don Black | Eighth | 26 out |
| Sunday, June 16 |
| » Lost to Indians (24-32), 2-1 | Cleveland Stadium (1-1) | 15-39 | Lost 2 |
| » Starters: Bob Savage vs Bob Feller | Eighth | 27 out |
| » Lost to Indians (25-32), 3-2 | Cleveland Stadium (1-2) | 15-40 | Lost 3 |
| » Starters: Lou Knerr vs Red Embree | Eighth | 27 out |
| Wednesday, June 19 |
| » Lost to Tigers (31-25), 3-0 | Tiger Stadium (0-3) | 15-41 | Lost 4 |
| » Starters: Russ Christopher vs Virgil Trucks | Seventh | 26½ out |
| Thursday, June 20 |
| » Lost to Tigers (32-25), 9-2 | Tiger Stadium (0-4) | 15-42 | Lost 5 |
| » Starters: Lou Knerr vs Dizzy Trout | Seventh | 26½ out |
| Friday, June 21 |
| » Defeated White Sox (22-33), 5-3 | Comiskey Park I (1-1) | 16-42 | |
| » Starters: Phil Marchildon vs Joe Haynes | Seventh | 26½ out |
| Saturday, June 22 |
| » Defeated White Sox (22-34), 5-2 | Comiskey Park I (2-1) | 17-42 | Won 2 |
| » Starters: Dick Fowler vs Ed Lopat | Seventh | 25½ out |
| Sunday, June 23 |
| » Lost to White Sox (23-34), 8-1 | Comiskey Park I (2-2) | 17-43 | |
| » Starters: Bob Savage vs Orval Grove | Eighth | 26½ out |
| » Defeated White Sox (23-35), 6-1 | Comiskey Park I (3-2) | 18-43 | |
| » Starters: Lum Harris vs Frank Papish | Eighth | 26½ out |
| Tuesday, June 25 |
| » Lost to Browns (29-34), 7-2 | Sportsman's Park III (2-2) | 18-44 | |
| » Starters: Lou Knerr vs Sam Zoldak | Eighth | 27½ out |
| Wednesday, June 26 |
| » Lost to Browns (30-34), 11-4 | Sportsman's Park III (2-3) | 18-45 | Lost 2 |
| » Starters: Dick Fowler vs Tex Shirley | Eighth | 28 out |
| Friday, June 28 |
| » Lost to Yankees (42-26), 4-1 | Yankee Stadium (0-6) | 18-46 | Lost 3 |
| » Starters: Phil Marchildon vs Bill Bevens | Eighth | 29 out |
| Saturday, June 29 |
| » Defeated Yankees (42-27), 2-0 | Yankee Stadium (1-6) | 19-46 | |
| » Starters: Russ Christopher vs Red Ruffing | Eighth | 29 out |
| Sunday, June 30 |
| » Defeated Yankees (42-28), 6-3 | Yankee Stadium (2-6) | 20-46 | Won 2 |
| » Starters: Lou Knerr vs Tiny Bonham | Eighth | 28½ out |
| Wednesday, July 3 |
| » Lost to Senators (34-33), 3-1 | Shibe Park (11-20) | 20-47 | |
| » Starters: Sid Hudson vs Lum Harris | Eighth | 28 out |
| Thursday, July 4 |
| » Defeated Red Sox (50-22), 3-2 | Shibe Park (12-20) | 21-47 | |
| » Starters: Dave Ferriss vs Phil Marchildon | Eighth | 28 out |
| » Lost to Red Sox (51-22), 9-8 | Shibe Park (12-21) | 21-48 | |
| » Starters: Bill Zuber vs Russ Christopher | Eighth | 28 out |
| Friday, July 5 |
| » Lost to Red Sox (52-22), 5-2 | Shibe Park (12-22) | 21-49 | Lost 2 |
| » Starters: Joe Dobson vs Dick Fowler | Eighth | 29 out |
| Saturday, July 6 |
| » Lost to Yankees (46-30), 8-5 | Shibe Park (12-23) | 21-50 | Lost 3 |
| » Starters: Cuddles Marshall vs Jesse Flores | Eighth | 29 out |
| Sunday, July 7 |
| » Lost to Yankees (47-30), 7-3 | Shibe Park (12-24) | 21-51 | Lost 4 |
| » Starters: Bill Bevens vs Lou Knerr | Eighth | 30 out |
| » Defeated Yankees (47-31), 4-1 | Shibe Park (13-24) | 22-51 | |
| » Starters: Spud Chandler vs Bob Savage | Eighth | 30 out |
| Thursday, July 11 |
| » Lost to Browns (35-41), 4-3 | Shibe Park (13-25) | 22-52 | |
| » Starters: Nels Potter vs Phil Marchildon | Eighth | 31 out |
| Friday, July 12 |
| » Defeated Browns (35-42), 7-2 | Shibe Park (14-25) | 23-52 | |
| » Starters: Jack Kramer vs Dick Fowler | Eighth | 31 out |
| Saturday, July 13 |
| » Lost to Browns (36-42), 11-4 | Shibe Park (14-26) | 23-53 | |
| » Starters: Cliff Fannin vs Lou Knerr | Eighth | 32 out |
| Sunday, July 14 |
| » Defeated White Sox (31-46), 5-4 | Shibe Park (15-26) | 24-53 | |
| » Starters: Orval Grove vs Russ Christopher | Eighth | 33 out |
| » Lost to White Sox (32-46), 4-3 | Shibe Park (15-27) | 24-54 | |
| » Starters: Joe Haynes vs Bob Savage | Eighth | 33 out |
| Monday, July 15 |
| » Defeated White Sox (32-47), 12-0 | Shibe Park (16-27) | 25-54 | |
| » Starters: Ralph Hamner vs Phil Marchildon | Seventh | 32½ out |
| Tuesday, July 16 |
| » Lost to White Sox (33-47), 6-2 | Shibe Park (16-28) | 25-55 | |
| » Starters: Eddie Smith vs Dick Fowler | Seventh | 32½ out |
| Wednesday, July 17 |
| » Lost to Indians (38-45), 8-2 | Shibe Park (16-29) | 25-56 | Lost 2 |
| » Starters: Allie Reynolds vs Lou Knerr | Eighth | 34 out |
| Thursday, July 18 |
| » Lost to Indians (39-45), 7-3 | Shibe Park (16-30) | 25-57 | Lost 3 |
| » Starters: Les Webber vs Russ Christopher | Eighth | 35 out |
| Friday, July 19 |
| » Lost to Indians (40-45), 6-1 | Shibe Park (16-31) | 25-58 | Lost 4 |
| » Starters: Mel Harder vs Bob Savage | Eighth | 36 out |
| Saturday, July 20 |
| » Lost to Tigers (48-36), 4-3 | Shibe Park (16-32) | 25-59 | Lost 5 |
| » Starters: Fred Hutchinson vs Phil Marchildon | Eighth | 36 out |
| Sunday, July 21 |
| » Defeated Tigers (48-37), 4-3 | Shibe Park (17-32) | 26-59 | |
| » Starters: Virgil Trucks vs Dick Fowler | Eighth | 37 out |
| » Lost to Tigers (49-37), 11-7 | Shibe Park (17-33) | 26-60 | |
| » Starters: Stubby Overmire vs Lum Harris | Eighth | 37 out |
| Tuesday, July 23 |
| » Lost to Indians (42-47), 2-0 | Cleveland Stadium (1-3) | 26-61 | Lost 2 |
| » Starters: Phil Marchildon vs Allie Reynolds | Eighth | 37 out |
| Wednesday, July 24 |
| » Lost to Indians (43-47), 1-0 | League Park II (0-4) | 26-62 | Lost 3 |
| » Starters: Bob Savage vs Bob Feller | Eighth | 38 out |
| Thursday, July 25 |
| » Lost to Indians (44-47), 9-8 | League Park II (0-5) | 26-63 | Lost 4 |
| » Starters: Lou Knerr vs Mel Harder | Eighth | 38 out |
| Friday, July 26 |
| » Lost to Tigers (51-39), 4-3 | Tiger Stadium (0-5) | 26-64 | Lost 5 |
| » Starters: Dick Fowler vs Virgil Trucks | Eighth | 39 out |
| Saturday, July 27 |
| » Lost to Tigers (52-39), 4-2 | Tiger Stadium (0-6) | 26-65 | Lost 6 |
| » Starters: Lum Harris vs Hal Newhouser | Eighth | 40 out |
| Sunday, July 28 |
| » Defeated Tigers (52-40), 2-0 | Tiger Stadium (1-6) | 27-65 | |
| » Starters: Jesse Flores vs Dizzy Trout | Eighth | 40 out |
| » Lost to Tigers (53-40), 6-2 | Tiger Stadium (1-7) | 27-66 | |
| » Starters: Phil Marchildon vs Stubby Overmire | Eighth | 40 out |
| Monday, July 29 |
| » Lost to Tigers (54-40), 4-1 | Tiger Stadium (1-8) | 27-67 | Lost 2 |
| » Starters: Lou Knerr vs Fred Hutchinson | Eighth | 40½ out |
| Tuesday, July 30 |
| » Defeated White Sox (38-58), 9-2 | Comiskey Park I (4-2) | 28-67 | |
| » Starters: Bob Savage vs Frank Papish | Eighth | 40½ out |
| Wednesday, July 31 |
| » Lost to White Sox (39-58), 3-2 | Comiskey Park I (4-3) | 28-68 | |
| » Starters: Dick Fowler vs Ed Lopat | Eighth | 40½ out |
| Thursday, August 1 |
| » Lost to White Sox (40-58), 7-6 | Comiskey Park I (4-4) | 28-69 | Lost 2 |
| » Starters: Lum Harris vs Joe Haynes | Eighth | 40½ out |
| Friday, August 2 |
| » Defeated Browns (43-55), 8-3 | Sportsman's Park III (3-3) | 29-69 | |
| » Starters: Phil Marchildon vs Denny Galehouse | Eighth | 39½ out |
| Saturday, August 3 |
| » Defeated Browns (43-56), 7-4 | Sportsman's Park III (4-3) | 30-69 | Won 2 |
| » Starters: Bob Savage vs Bob Muncrief | Eighth | 39½ out |
| Sunday, August 4 |
| » Lost to Browns (44-56), 6-5 | Sportsman's Park III (4-4) | 30-70 | |
| » Starters: Lou Knerr vs Stan Ferens | Eighth | 41 out |
| » Lost to Browns (45-56), 7-4 | Sportsman's Park III (4-5) | 30-71 | Lost 2 |
| » Starters: Jesse Flores vs Tex Shirley | Eighth | 41 out |
| Tuesday, August 6 |
| » Lost to Red Sox (73-31), 5-0 | Fenway Park (1-4) | 30-72 | Lost 3 |
| » Starters: Dick Fowler vs Tex Hughson | Eighth | 42 out |
| Former Athletic Tad Quinn dies in Waterbury, CT at the age of 64. |
| Thursday, August 8 |
| » Lost to Red Sox (74-31), 4-3 | Fenway Park (1-5) | 30-73 | Lost 4 |
| » Starters: Phil Marchildon vs Joe Dobson | Eighth | 44 out |
| » Lost to Red Sox (75-31), 10-6 | Fenway Park (1-6) | 30-74 | Lost 5 |
| » Starters: Bob Savage vs Bill Zuber | Eighth | 44 out |
| Friday, August 9 |
| » Lost to Senators (53-53), 2-1 | Griffith Stadium (0-5) | 30-75 | Lost 6 |
| » Starters: Lum Harris vs Mickey Haefner | Eighth | 45 out |
| Saturday, August 10 |
| » Lost to Senators (54-53), 4-1 | Griffith Stadium (0-6) | 30-76 | Lost 7 |
| » Starters: Dick Fowler vs Early Wynn | Eighth | 44½ out |
| » Defeated Senators (54-54), 8-3 | Griffith Stadium (1-6) | 31-76 | |
| » Starters: Jesse Flores vs Sid Hudson | Eighth | 44½ out |
| Sunday, August 11 |
| » Lost to Senators (55-54), 3-1 | Griffith Stadium (1-7) | 31-77 | |
| » Starters: Lou Knerr vs Bobo Newsom | Eighth | 44½ out |
| » Defeated Senators (55-55), 12-5 | Griffith Stadium (2-7) | 32-77 | |
| » Starters: Phil Marchildon vs Ray Scarborough | Eighth | 44½ out |
| Tuesday, August 13 |
| » Lost to Red Sox (78-33), 7-5 | Shibe Park (17-34) | 32-78 | |
| » Starters: Dave Ferriss vs Bob Savage | Eighth | 45½ out |
| Wednesday, August 14 |
| » Lost to Red Sox (79-33), 3-1 | Shibe Park (17-35) | 32-79 | Lost 2 |
| » Starters: Tex Hughson vs Dick Fowler | Eighth | 46½ out |
| Thursday, August 15 |
| » Defeated Red Sox (79-34), 5-3 | Shibe Park (18-35) | 33-79 | |
| » Starters: Joe Dobson vs Lou Knerr | Eighth | 45½ out |
| Saturday, August 17 |
| » Lost to Senators (56-58), 12-7 | Shibe Park (18-36) | 33-80 | |
| » Starters: Bobo Newsom vs Lum Harris | Eighth | 46½ out |
| » Defeated Senators (56-59), 5-3 | Shibe Park (19-36) | 34-80 | |
| » Starters: Ray Scarborough vs Phil Marchildon | Eighth | 46½ out |
| Sunday, August 18 |
| » Defeated Senators (56-60), 11-0 | Shibe Park (20-36) | 35-80 | Won 2 |
| » Starters: Dutch Leonard vs Jesse Flores | Eighth | 46½ out |
| » Lost to Senators (57-60), 6-4 | Shibe Park (20-37) | 35-81 | |
| » Starters: Roger Wolff vs Dick Fowler | Eighth | 46½ out |
| Tuesday, August 20 |
| » Defeated Tigers (64-50), 2-0 | Shibe Park (21-37) | 36-81 | |
| » Starters: Hal Newhouser vs Bob Savage | Eighth | 46 out |
| Wednesday, August 21 |
| » Defeated Tigers (64-51), 4-1 | Shibe Park (22-37) | 37-81 | Won 2 |
| » Starters: Virgil Trucks vs Phil Marchildon | Eighth | 46 out |
| Thursday, August 22 |
| » Defeated Indians (56-64), 8-6 | Shibe Park (23-37) | 38-81 | Won 3 |
| » Starters: Allie Reynolds vs Dick Fowler | Eighth | 45 out |
| Friday, August 23 |
| » Defeated Indians (56-65), 1-0 | Shibe Park (24-37) | 39-81 | Won 4 |
| » Starters: Mel Harder vs Jesse Flores | Eighth | 44½ out |
| Saturday, August 24 |
| » Lost to Indians (57-65), 5-0 | Shibe Park (24-38) | 39-82 | |
| » Starters: Bob Feller vs Lum Harris | Eighth | 45 out |
| Sunday, August 25 |
| » Lost to White Sox (56-67), 4-2 | Shibe Park (24-39) | 39-83 | Lost 2 |
| » Starters: Ed Lopat vs Bob Savage | Eighth | 46 out |
| » Defeated White Sox (56-68), 6-5 | Shibe Park (25-39) | 40-83 | |
| » Starters: Joe Haynes vs Phil Marchildon | Eighth | 46 out |
| Future Athletic Rollie Fingers is born in Steubenville, OH. |
| Monday, August 26 |
| » Defeated White Sox (56-69), 3-0 | Shibe Park (26-39) | 41-83 | Won 2 |
| » Starters: Ralph Hamner vs Dick Fowler | Eighth | 46 out |
| Tuesday, August 27 |
| » Defeated White Sox (56-70), 5-2 | Shibe Park (27-39) | 42-83 | Won 3 |
| » Starters: Eddie Smith vs Jesse Flores | Eighth | 45½ out |
| Wednesday, August 28 |
| » Lost to Browns (53-71), 7-0 | Shibe Park (27-40) | 42-84 | |
| » Starters: Denny Galehouse vs Russ Christopher | Eighth | 45½ out |
| Thursday, August 29 |
| Future Athletic Bill McNulty is born in Sacramento, CA. |
| Friday, August 30 |
| » Lost to Red Sox (89-40), 6-0 | Fenway Park (1-7) | 42-85 | Lost 2 |
| » Starters: Lou Knerr vs Tex Hughson | Seventh | 47 out |
| » Lost to Red Sox (90-40), 6-2 | Fenway Park (1-8) | 42-86 | Lost 3 |
| » Starters: Phil Marchildon vs Jim Bagby | Seventh | 47 out |
| Saturday, August 31 |
| » Lost to Red Sox (91-40), 4-2 | Fenway Park (1-9) | 42-87 | Lost 4 |
| » Starters: Dick Fowler vs Bill Zuber | Eighth | 48 out |
| Sunday, September 1 |
| » Lost to Red Sox (92-40), 4-3 | Fenway Park (1-10) | 42-88 | Lost 5 |
| » Starters: Bob Savage vs Joe Dobson | Seventh | 49 out |
| Monday, September 2 |
| » Lost to Senators (63-66), 5-2 | Griffith Stadium (2-8) | 42-89 | Lost 6 |
| » Starters: Lum Harris vs Bobo Newsom | Eighth | 50 out |
| » Defeated Senators (63-67), 7-1 | Griffith Stadium (3-8) | 43-89 | |
| » Starters: Jesse Flores vs Early Wynn | Eighth | 50 out |
| Wednesday, September 4 |
| » Defeated Yankees (77-55), 4-3 | Shibe Park (28-40) | 44-89 | Won 2 |
| » Starters: Bill Bevens vs Phil Marchildon | Seventh | 50 out |
| Thursday, September 5 |
| » Lost to Yankees (78-55), 6-2 | Shibe Park (28-41) | 44-90 | |
| » Starters: Randy Gumpert vs Dick Fowler | Eighth | 51 out |
| Friday, September 6 |
| » Defeated Yankees (78-56), 4-3 | Shibe Park (29-41) | 45-90 | |
| » Starters: Cuddles Marshall vs Bob Savage | Eighth | 50 out |
| Saturday, September 7 |
| » Defeated Red Sox (96-42), 4-2 | Shibe Park (30-41) | 46-90 | Won 2 |
| » Starters: Dave Ferriss vs Jesse Flores | Eighth | 49 out |
| Sunday, September 8 |
| » Defeated Red Sox (96-43), 5-3 | Shibe Park (31-41) | 47-90 | Won 3 |
| » Starters: Tex Hughson vs Phil Marchildon | Eighth | 48 out |
| Monday, September 9 |
| » Major-league debuts: Sheldon Jones (Giants) |
| Tuesday, September 10 |
| » Lost to Browns (58-76), 5-1 | Sportsman's Park III (4-6) | 47-91 | |
| » Starters: Dick Fowler vs Cliff Fannin | Eighth | 48 out |
| » Major-league debuts: Les Moss (Browns) |
| Wednesday, September 11 |
| » Lost to Browns (59-76), 4-0 | Sportsman's Park III (4-7) | 47-92 | Lost 2 |
| » Starters: Lou Knerr vs Ellis Kinder | Eighth | 48 out |
| Thursday, September 12 |
| » Major-league debuts: Chet Johnson (Browns) |
| Friday, September 13 |
| » Lost to White Sox (65-75), 3-1 | Comiskey Park I (4-5) | 47-93 | Lost 3 |
| » Starters: Bob Savage vs Orval Grove | Eighth | 49 out |
| » Lost to White Sox (66-75), 4-2 | Comiskey Park I (4-6) | 47-94 | Lost 4 |
| » Starters: Phil Marchildon vs Frank Papish | Eighth | 49 out |
| Saturday, September 14 |
| » Defeated White Sox (66-76), 1-0 | Comiskey Park I (5-6) | 48-94 | |
| » Starters: Jesse Flores vs Ed Lopat | Eighth | 48½ out |
| Sunday, September 15 |
| » Lost to Indians (65-78), 8-1 | Cleveland Stadium (1-4) | 48-95 | |
| » Starters: Joe Coleman vs Bob Lemon | Eighth | 48½ out |
| » Defeated Indians (65-79), 2-0 | Cleveland Stadium (2-4) | 49-95 | |
| » Starters: Bill McCahan vs Bob Feller | Eighth | 48½ out |
| » Major-league debuts: Dale Mitchell (Indians) |
| Wednesday, September 18 |
| » Lost to Tigers (83-59), 2-1 | Tiger Stadium (1-9) | 49-96 | |
| » Starters: Phil Marchildon vs Hal Newhouser | Eighth | 49½ out |
| Thursday, September 19 |
| » Lost to Tigers (84-59), 14-7 | Tiger Stadium (1-10) | 49-97 | Lost 2 |
| » Starters: Joe Coleman vs Virgil Trucks | Eighth | 49½ out |
| Sunday, September 22 |
| » Lost to Yankees (83-65), 4-3 | Yankee Stadium (2-7) | 49-98 | Lost 3 |
| » Starters: Jesse Flores vs Spud Chandler | Eighth | 51½ out |
| » Lost to Yankees (84-65), 7-4 | Yankee Stadium (2-8) | 49-99 | Lost 4 |
| » Starters: Phil Marchildon vs Cuddles Marshall | Eighth | 51½ out |
| » Major-league debuts: Yogi Berra and Bobby Brown (Yankees) |
| Monday, September 23 |
| » Lost to Yankees (85-65), 9-6 | Yankee Stadium (2-9) | 49-100 | Lost 5 |
| » Starters: Bob Savage vs Vic Raschi | Eighth | 52 out |
| » Major-league debuts: Vic Raschi (Yankees) |
| Wednesday, September 25 |
| » Lost to Senators (72-77), 6-3 | Shibe Park (31-42) | 49-101 | Lost 6 |
| » Starters: Roger Wolff vs Lum Harris | Eighth | 54 out |
| » Lost to Senators (73-77), 7-4 | Shibe Park (31-43) | 49-102 | Lost 7 |
| » Starters: Dutch Leonard vs Lou Knerr | Eighth | 54 out |
| Thursday, September 26 |
| » Lost to Senators (74-77), 2-0 | Shibe Park (31-44) | 49-103 | Lost 8 |
| » Starters: Mickey Haefner vs Jesse Flores | Eighth | 54½ out |
| Sunday, September 29 |
| » Lost to Yankees (86-67), 6-0 | Shibe Park (31-45) | 49-104 | Lost 9 |
| » Starters: Spud Chandler vs Phil Marchildon | Eighth | 55 out |
| » Lost to Yankees (87-67), 2-1 | Shibe Park (31-46) | 49-105 | Lost 10 |
| » Starters: Vic Raschi vs Bill McCahan | Eighth | 55 out |
Game information provided by Retrosheet (www.retrosheet.org) |