| Wednesday, January 3 |
| Former Red Sox George Stone dies in Clinton, IA at the age of 68. |
| Sunday, January 7 |
| Future Red Sox Tony Conigliaro is born in Revere, MA. |
| Monday, January 29 |
| Future Red Sox Dick Mills is born in Boston, MA. |
| Thursday, February 1 |
| Former Red Sox Tubby Spencer dies in San Francisco, CA at the age of 62. |
| Monday, April 2 |
| Future Red Sox Reggie Smith is born in Shreveport, LA. |
| Sunday, April 15 |
| Future Red Sox Ted Sizemore is born in Gadsden, AL. |
| Monday, April 16 |
| Former Red Sox Chick Fewster dies in Baltimore, MD at the age of 50. |
| Tuesday, April 17 |
| » Lost to Yankees (1-0), 8-4 | Yankee Stadium (0-1) | 0-1 | |
| » Starters: Rex Cecil vs Atley Donald | Second | 1 out |
| Wednesday, April 18 |
| » Lost to Yankees (2-0), 6-2 | Yankee Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Jim Wilson vs Hank Borowy | Fifth | 2 out |
| » Major-league debuts: Jim Wilson (Red Sox) |
| Thursday, April 19 |
| » Lost to Yankees (3-0), 4-3 | Yankee Stadium (0-3) | 0-3 | Lost 3 |
| » Starters: Clem Dreisewerd vs Monk Dubiel | Sixth | 3 out |
| Friday, April 20 |
| » Lost to Athletics (2-2), 5-3 | Fenway Park (0-1) | 0-4 | Lost 4 |
| » Starters: Don Black vs Joe Bowman | Sixth | 4 out |
| Saturday, April 21 |
| » Lost to Athletics (3-2), 8-2 | Fenway Park (0-2) | 0-5 | Lost 5 |
| » Starters: Bobo Newsom vs Clem Hausmann | Fifth | 4 out |
| Sunday, April 22 |
| » Lost to Athletics (4-2), 6-1 | Fenway Park (0-3) | 0-6 | Lost 6 |
| » Starters: Russ Christopher vs Rex Cecil | Seventh | 5½ out |
| Thursday, April 26 |
| » Lost to Senators (4-3), 4-1 | Griffith Stadium (0-1) | 0-7 | Lost 7 |
| » Starters: Clem Dreisewerd vs Johnny Niggeling | Seventh | 6 out |
| Friday, April 27 |
| » Lost to Athletics (6-2), 5-3 | Shibe Park (0-1) | 0-8 | Lost 8 |
| » Starters: Emmett O'Neill vs Russ Christopher | Seventh | 6½ out |
| Saturday, April 28 |
| » Defeated Athletics (6-3), 8-4 | Shibe Park (1-1) | 1-8 | |
| » Starters: Rex Cecil vs Don Black | Seventh | 6 out |
| Sunday, April 29 |
| » Defeated Athletics (6-4), 2-0 | Shibe Park (2-1) | 2-8 | Won 2 |
| » Starters: Dave Ferriss vs Bobo Newsom | Sixth | 4 out |
| » Defeated Athletics (6-5), 6-3 | Shibe Park (3-1) | 3-8 | Won 3 |
| » Starters: Joe Bowman vs Jesse Flores | Sixth | 4 out |
| Tuesday, May 1 |
| » Defeated Senators (6-6), 5-4 | Fenway Park (1-3) | 4-8 | Won 4 |
| » Starters: Johnny Niggeling vs Emmett O'Neill | Seventh | 4 out |
| Wednesday, May 2 |
| » Defeated Senators (6-7), 4-0 | Fenway Park (2-3) | 5-8 | Won 5 |
| » Starters: Mickey Haefner vs Jim Wilson | Seventh | 3½ out |
| Saturday, May 5 |
| » Lost to Yankees (9-4), 7-3 | Fenway Park (2-4) | 5-9 | |
| » Starters: Monk Dubiel vs Rex Cecil | Seventh | 4 out |
| Sunday, May 6 |
| » Defeated Yankees (9-5), 5-0 | Fenway Park (3-4) | 6-9 | |
| » Starters: Tiny Bonham vs Dave Ferriss | Seventh | 5 out |
| » Lost to Yankees (10-5), 2-0 | Fenway Park (3-5) | 6-10 | |
| » Starters: Hank Borowy vs Emmett O'Neill | Seventh | 5 out |
| Tuesday, May 8 |
| » Major-league debuts: Frank Papish (White Sox) |
| Wednesday, May 9 |
| » Lost to Indians (5-10), 2-1 | League Park II (0-1) | 6-11 | Lost 2 |
| » Starters: Jim Wilson vs Allie Reynolds | Seventh | 5½ out |
| Friday, May 11 |
| » Defeated Indians (5-11), 8-4 | League Park II (1-1) | 7-11 | |
| » Starters: Rex Cecil vs Al Smith | Seventh | 4½ out |
| » Major-league debuts: Red Steiner (Indians) |
| Sunday, May 13 |
| » Defeated Tigers (10-7), 8-2 | Tiger Stadium (1-0) | 8-11 | Won 2 |
| » Starters: Dave Ferriss vs Dizzy Trout | Seventh | 5 out |
| » Lost to Tigers (11-7), 2-0 | Tiger Stadium (1-1) | 8-12 | |
| » Starters: Jim Wilson vs Al Benton | Seventh | 5 out |
| Thursday, May 17 |
| » Major-league debuts: Cy Buker (Dodgers) |
| Friday, May 18 |
| » Defeated White Sox (12-7), 2-0 | Comiskey Park I (1-0) | 9-12 | |
| » Starters: Dave Ferriss vs Joe Haynes | Sixth | 4 out |
| Saturday, May 19 |
| » Lost to White Sox (13-7), 3-2 | Comiskey Park I (1-1) | 9-13 | |
| » Starters: Jim Wilson vs Johnny Humphries | Sixth | 5 out |
| Sunday, May 20 |
| » Lost to White Sox (14-7), 4-2 | Comiskey Park I (1-2) | 9-14 | Lost 2 |
| » Starters: Rex Cecil vs Thornton Lee | Seventh | 7 out |
| » Lost to White Sox (15-7), 8-2 | Comiskey Park I (1-3) | 9-15 | Lost 3 |
| » Starters: Joe Bowman vs Orval Grove | Seventh | 7 out |
| Wednesday, May 23 |
| » Defeated Browns (13-10), 4-1 | Fenway Park (4-5) | 10-15 | |
| » Starters: Sig Jakucki vs Dave Ferriss | Seventh | 6 out |
| Thursday, May 24 |
| » Defeated Browns (13-11), 8-6 | Fenway Park (5-5) | 11-15 | Won 2 |
| » Starters: Jack Kramer vs Pinky Woods | Seventh | 5 out |
| Friday, May 25 |
| » Lost to Browns (14-11), 5-0 | Fenway Park (5-6) | 11-16 | |
| » Starters: Nels Potter vs Jim Wilson | Sixth | 5½ out |
| Saturday, May 26 |
| » Lost to Browns (15-11), 9-2 | Fenway Park (5-7) | 11-17 | Lost 2 |
| » Starters: Tex Shirley vs Oscar Judd | Sixth | 6½ out |
| Sunday, May 27 |
| » Defeated White Sox (15-12), 7-0 | Fenway Park (6-7) | 12-17 | |
| » Starters: Ed Lopat vs Dave Ferriss | Fifth | 6½ out |
| » Defeated White Sox (15-13), 2-1 | Fenway Park (7-7) | 13-17 | Won 2 |
| » Starters: Joe Haynes vs Emmett O'Neill | Fifth | 6½ out |
| Former Red Sox Walter Carlisle dies in Los Angeles, CA at the age of 62. |
| Monday, May 28 |
| » Lost to White Sox (16-13), 8-6 | Fenway Park (7-8) | 13-18 | |
| » Starters: Orval Grove vs Rex Cecil | Sixth | 7 out |
| Tuesday, May 29 |
| » Defeated White Sox (16-14), 6-4 | Fenway Park (8-8) | 14-18 | |
| » Starters: Buck Ross vs Pinky Woods | Sixth | 7 out |
| Wednesday, May 30 |
| » Lost to Indians (14-15), 4-3 | Fenway Park (8-9) | 14-19 | |
| » Starters: Steve Gromek vs Jim Wilson | Seventh | 7 out |
| » Defeated Indians (14-16), 7-6 | Fenway Park (9-9) | 15-19 | |
| » Starters: Jim Bagby vs Yank Terry | Seventh | 7 out |
| Thursday, May 31 |
| » Defeated Indians (14-17), 6-2 | Fenway Park (10-9) | 16-19 | Won 2 |
| » Starters: Red Embree vs Dave Ferriss | Fifth | 6 out |
| Friday, June 1 |
| » Defeated Tigers (19-13), 6-4 | Fenway Park (11-9) | 17-19 | Won 3 |
| » Starters: Walter Wilson vs Emmett O'Neill | Fifth | 6 out |
| » Major-league debuts: Billy Pierce (Tigers) |
| Saturday, June 2 |
| » Defeated Tigers (19-14), 5-1 | Fenway Park (12-9) | 18-19 | Won 4 |
| » Starters: Joe Orrell vs Clem Hausmann | Fifth | 5 out |
| Sunday, June 3 |
| » Defeated Tigers (19-15), 4-3 | Fenway Park (13-9) | 19-19 | Won 5 |
| » Starters: Dizzy Trout vs Jim Wilson | Fifth | 5 out |
| » Lost to Tigers (20-15), 4-3 | Fenway Park (13-10) | 19-20 | |
| » Starters: Hal Newhouser vs Yank Terry | Fifth | 5 out |
| Wednesday, June 6 |
| » Defeated Athletics (15-24), 5-2 | Fenway Park (14-10) | 20-20 | |
| » Starters: Lou Knerr vs Dave Ferriss | Fifth | 3½ out |
| » Defeated Athletics (15-25), 3-2 | Fenway Park (15-10) | 21-20 | Won 2 |
| » Starters: Jesse Flores vs Pinky Woods | Fifth | 3½ out |
| Thursday, June 7 |
| » Defeated Athletics (15-26), 5-4 | Fenway Park (16-10) | 22-20 | Won 3 |
| » Starters: Charlie Gassaway vs Jim Wilson | Fourth | 3 out |
| Friday, June 8 |
| » Defeated Yankees (25-18), 6-4 | Yankee Stadium (1-3) | 23-20 | Won 4 |
| » Starters: Clem Hausmann vs Tiny Bonham | Third | 2 out |
| Saturday, June 9 |
| » Lost to Yankees (26-18), 13-7 | Yankee Stadium (1-4) | 23-21 | |
| » Starters: Emmett O'Neill vs Bill Bevens | Third | 3 out |
| Sunday, June 10 |
| » Lost to Yankees (27-18), 3-2 | Yankee Stadium (1-5) | 23-22 | Lost 2 |
| » Starters: Dave Ferriss vs Hank Borowy | Fourth | 4 out |
| Tuesday, June 12 |
| » Lost to Athletics (17-27), 7-5 | Shibe Park (3-2) | 23-23 | Lost 3 |
| » Starters: Jim Wilson vs Jesse Flores | Fourth | 4½ out |
| Thursday, June 14 |
| » Defeated Athletics (17-28), 1-0 | Shibe Park (4-2) | 24-23 | |
| » Starters: Clem Hausmann vs Bobo Newsom | Third | 4 out |
| Friday, June 15 |
| » Defeated Senators (21-24), 6-5 | Griffith Stadium (1-1) | 25-23 | Won 2 |
| » Starters: Dave Ferriss vs Marino Pieretti | Third | 3½ out |
| » Tied Senators, 4-4 | Griffith Stadium (1-1) | 25-23 | |
| » Starters: Mike Ryba vs Johnny Niggeling | Third | 3½ out |
| Saturday, June 16 |
| » Lost to Senators (22-24), 4-0 | Griffith Stadium (1-2) | 25-24 | |
| » Starters: Yank Terry vs Mickey Haefner | Third | 5 out |
| Sunday, June 17 |
| » Defeated Senators (22-25), 2-1 | Griffith Stadium (2-2) | 26-24 | |
| » Starters: Emmett O'Neill vs Dutch Leonard | Third | 3 out |
| » Defeated Senators (22-26), 7-1 | Griffith Stadium (3-2) | 27-24 | Won 2 |
| » Starters: Jim Wilson vs Sandy Ullrich | Third | 3 out |
| Tuesday, June 19 |
| » Defeated Yankees (28-23), 1-0 | Fenway Park (17-10) | 28-24 | Won 3 |
| » Starters: Hank Borowy vs Clem Hausmann | Third | 2½ out |
| Thursday, June 21 |
| » Lost to Yankees (29-23), 14-4 | Fenway Park (17-11) | 28-25 | |
| » Starters: Monk Dubiel vs Dave Ferriss | Third | 4 out |
| Friday, June 22 |
| » Defeated Senators (25-27), 10-5 | Fenway Park (18-11) | 29-25 | |
| » Starters: Johnny Niggeling vs Emmett O'Neill | Third | 3 out |
| Saturday, June 23 |
| » Lost to Senators (26-27), 6-5 | Fenway Park (18-12) | 29-26 | |
| » Starters: Roger Wolff vs Jim Wilson | Third | 4 out |
| Sunday, June 24 |
| » Defeated Senators (26-28), 6-5 | Fenway Park (19-12) | 30-26 | |
| » Starters: Mickey Haefner vs Dave Ferriss | Third | 5 out |
| » Lost to Senators (27-28), 5-2 | Fenway Park (19-13) | 30-27 | |
| » Starters: Marino Pieretti vs Clem Hausmann | Third | 5 out |
| Monday, June 25 |
| Future Red Sox Dick Drago is born in Toledo, OH. |
| Wednesday, June 27 |
| » Defeated White Sox (31-29), 11-9 | Comiskey Park I (2-3) | 31-27 | |
| » Starters: Emmett O'Neill vs Orval Grove | Second | 4 out |
| Friday, June 29 |
| » Defeated White Sox (31-30), 4-2 | Comiskey Park I (3-3) | 32-27 | Won 2 |
| » Starters: Dave Ferriss vs Johnny Humphries | Third | 3½ out |
| Saturday, June 30 |
| » Tied Browns, 2-2 | Sportsman's Park III (0-0) | 32-27 | |
| » Starters: Clem Hausmann vs Nels Potter | Third | 4 out |
| Sunday, July 1 |
| » Lost to Browns (27-31), 7-3 | Sportsman's Park III (0-1) | 32-28 | |
| » Starters: Emmett O'Neill vs Bob Muncrief | Third | 5 out |
| » Defeated Browns (27-32), 7-4 | Sportsman's Park III (1-1) | 33-28 | |
| » Starters: Mike Ryba vs Tex Shirley | Third | 5 out |
| Future Red Sox Billy Rohr is born in San Diego, CA. |
| Monday, July 2 |
| » Lost to Browns (28-32), 7-1 | Sportsman's Park III (1-2) | 33-29 | |
| » Starters: Yank Terry vs Sig Jakucki | Fourth | 6 out |
| » Lost to Browns (29-32), 3-2 | Sportsman's Park III (1-3) | 33-30 | Lost 2 |
| » Starters: Randy Heflin vs Jack Kramer | Fourth | 6 out |
| Tuesday, July 3 |
| » Defeated Tigers (39-25), 4-0 | Tiger Stadium (2-1) | 34-30 | |
| » Starters: Jim Wilson vs Hal Newhouser | Third | 5 out |
| Wednesday, July 4 |
| » Defeated Tigers (39-26), 4-3 | Tiger Stadium (3-1) | 35-30 | Won 2 |
| » Starters: Dave Ferriss vs Dizzy Trout | Fourth | 5 out |
| » Lost to Tigers (40-26), 5-2 | Tiger Stadium (3-2) | 35-31 | |
| » Starters: Clem Hausmann vs Al Benton | Fourth | 5 out |
| Thursday, July 5 |
| » Lost to Tigers (41-26), 9-8 | Tiger Stadium (3-3) | 35-32 | Lost 2 |
| » Starters: Mike Ryba vs Les Mueller | Fourth | 6 out |
| Friday, July 6 |
| » Lost to Indians (31-35), 3-2 | Cleveland Stadium (0-1) | 35-33 | Lost 3 |
| » Starters: Emmett O'Neill vs Jim Bagby | Fourth | 6½ out |
| » Lost to Indians (32-35), 4-2 | Cleveland Stadium (0-2) | 35-34 | Lost 4 |
| » Starters: Randy Heflin vs Mel Harder | Fourth | 6½ out |
| Saturday, July 7 |
| » Defeated Indians (32-36), 8-6 | League Park II (2-1) | 36-34 | |
| » Starters: Jim Wilson vs Al Smith | Fourth | 6½ out |
| Future Red Sox Chuck Goggin is born in Pompano Beach, FL. |
| Sunday, July 8 |
| » Defeated Indians (32-37), 6-0 | Cleveland Stadium (1-2) | 37-34 | Won 2 |
| » Starters: Dave Ferriss vs Steve Gromek | Fifth | 6½ out |
| » Lost to Indians (33-37), 4-2 | Cleveland Stadium (1-3) | 37-35 | |
| » Starters: Clem Hausmann vs Pete Center | Fifth | 6½ out |
| Thursday, July 12 |
| » Defeated Tigers (43-29), 2-1 | Fenway Park (20-13) | 38-35 | |
| » Starters: Hal Newhouser vs Jim Wilson | Fourth | 5½ out |
| Friday, July 13 |
| » Defeated Tigers (43-30), 5-1 | Fenway Park (21-13) | 39-35 | Won 2 |
| » Starters: Stubby Overmire vs Dave Ferriss | Third | 4½ out |
| Saturday, July 14 |
| » Defeated Tigers (43-31), 7-1 | Fenway Park (22-13) | 40-35 | Won 3 |
| » Starters: Les Mueller vs Emmett O'Neill | Third | 3½ out |
| Sunday, July 15 |
| » Defeated Indians (35-39), 6-4 | Fenway Park (23-13) | 41-35 | Won 4 |
| » Starters: Mel Harder vs Clem Hausmann | Third | 2½ out |
| Monday, July 16 |
| » Lost to Indians (36-39), 3-2 | Fenway Park (23-14) | 41-36 | |
| » Starters: Allie Reynolds vs Randy Heflin | Third | 3½ out |
| Tuesday, July 17 |
| » Lost to Indians (37-39), 6-1 | Fenway Park (23-15) | 41-37 | Lost 2 |
| » Starters: Steve Gromek vs Jim Wilson | Fourth | 4 out |
| Wednesday, July 18 |
| » Defeated White Sox (40-40), 6-2 | Fenway Park (24-15) | 42-37 | |
| » Starters: Bill Dietrich vs Dave Ferriss | Second | 4½ out |
| Thursday, July 19 |
| » Lost to White Sox (41-40), 5-3 | Fenway Park (24-16) | 42-38 | |
| » Starters: Thornton Lee vs Emmett O'Neill | Fourth | 5 out |
| Friday, July 20 |
| » Lost to White Sox (42-40), 6-3 | Fenway Park (24-17) | 42-39 | Lost 2 |
| » Starters: Ed Lopat vs Clem Hausmann | Third | 4½ out |
| Saturday, July 21 |
| » Lost to Browns (40-38), 4-1 | Fenway Park (24-18) | 42-40 | Lost 3 |
| » Starters: Nels Potter vs Jim Wilson | Fifth | 5 out |
| Sunday, July 22 |
| » Defeated Browns (40-39), 3-2 | Fenway Park (25-18) | 43-40 | |
| » Starters: Jack Kramer vs Dave Ferriss | Fourth | 5 out |
| » Lost to Browns (41-39), 5-1 | Fenway Park (25-19) | 43-41 | |
| » Starters: Tex Shirley vs Randy Heflin | Fourth | 5 out |
| Tuesday, July 24 |
| » Defeated Browns (41-40), 6-0 | Fenway Park (26-19) | 44-41 | |
| » Starters: Sig Jakucki vs Emmett O'Neill | Third | 4 out |
| Friday, July 27 |
| » Lost to Senators (45-39), 3-1 | Fenway Park (26-20) | 44-42 | |
| » Starters: Roger Wolff vs Dave Ferriss | Fourth | 5 out |
| Saturday, July 28 |
| » Defeated Senators (45-40), 6-2 | Fenway Park (27-20) | 45-42 | |
| » Starters: Marino Pieretti vs Jim Wilson | Fourth | 5 out |
| Sunday, July 29 |
| » Defeated Senators (45-41), 8-4 | Fenway Park (28-20) | 46-42 | Won 2 |
| » Starters: Johnny Niggeling vs Emmett O'Neill | Third | 5 out |
| Tuesday, July 31 |
| » Lost to Yankees (47-40), 4-2 | Fenway Park (28-21) | 46-43 | |
| » Starters: Monk Dubiel vs Dave Ferriss | Fourth | 6 out |
| Wednesday, August 1 |
| » Defeated Yankees (47-41), 7-5 | Fenway Park (29-21) | 47-43 | |
| » Starters: Bill Bevens vs Jim Wilson | Third | 6 out |
| Thursday, August 2 |
| » Lost to Yankees (48-41), 3-1 | Fenway Park (29-22) | 47-44 | |
| » Starters: Red Ruffing vs Clem Hausmann | Fourth | 7 out |
| Friday, August 3 |
| » Lost to Senators (50-41), 7-3 | Griffith Stadium (3-3) | 47-45 | Lost 2 |
| » Starters: Emmett O'Neill vs Alex Carrasquel | Fourth | 7½ out |
| » Lost to Senators (51-41), 3-1 | Griffith Stadium (3-4) | 47-46 | Lost 3 |
| » Starters: Jim Wilson vs Johnny Niggeling | Fourth | 7½ out |
| Saturday, August 4 |
| » Lost to Senators (52-41), 4-0 | Griffith Stadium (3-5) | 47-47 | Lost 4 |
| » Starters: Vic Johnson vs Wally Holborow | Fourth | 7 out |
| » Defeated Senators (52-42), 15-4 | Griffith Stadium (4-5) | 48-47 | |
| » Starters: Dave Ferriss vs Sandy Ullrich | Fourth | 7 out |
| » Major-league debuts: Joe Cleary and Bert Shepard (Senators) |
| Sunday, August 5 |
| » Lost to Senators (53-42), 5-4 | Griffith Stadium (4-6) | 48-48 | |
| » Starters: Pinky Woods vs Dutch Leonard | Fifth | 7 out |
| » Lost to Senators (54-42), 5-1 | Griffith Stadium (4-7) | 48-49 | Lost 2 |
| » Starters: Clem Hausmann vs Roger Wolff | Fifth | 7 out |
| Tuesday, August 7 |
| Former Red Sox Bobby Veach dies in Detroit, MI at the age of 58. |
| Wednesday, August 8 |
| » Lost to Tigers (55-41), 5-2 | Tiger Stadium (3-4) | 48-50 | Lost 3 |
| » Starters: Dave Ferriss vs Stubby Overmire | Sixth | 7 out |
| » Defeated Tigers (55-42), 7-4 | Tiger Stadium (4-4) | 49-50 | |
| » Starters: Jim Wilson vs Hal Newhouser | Sixth | 7 out |
| Thursday, August 9 |
| » Lost to Tigers (56-42), 11-5 | Tiger Stadium (4-5) | 49-51 | |
| » Starters: Emmett O'Neill vs Dizzy Trout | Sixth | 8 out |
| Friday, August 10 |
| » Defeated Tigers (56-43), 9-0 | Tiger Stadium (5-5) | 50-51 | |
| » Starters: Randy Heflin vs Al Benton | Sixth | 7 out |
| Saturday, August 11 |
| » Lost to Tigers (57-43), 5-4 | Tiger Stadium (5-6) | 50-52 | |
| » Starters: Pinky Woods vs Les Mueller | Seventh | 8 out |
| Sunday, August 12 |
| » Defeated Indians (50-51), 7-1 | Cleveland Stadium (2-3) | 51-52 | |
| » Starters: Dave Ferriss vs Mel Harder | Seventh | 9 out |
| » Lost to Indians (51-51), 8-2 | Cleveland Stadium (2-4) | 51-53 | |
| » Starters: Otie Clark vs Pete Center | Seventh | 9 out |
| Monday, August 13 |
| » Lost to Indians (52-51), 10-0 | Cleveland Stadium (2-5) | 51-54 | Lost 2 |
| » Starters: Vic Johnson vs Al Smith | Seventh | 10½ out |
| Tuesday, August 14 |
| » Lost to Indians (53-51), 3-0 | League Park II (2-2) | 51-55 | Lost 3 |
| » Starters: Randy Heflin vs Jim Bagby | Seventh | 11 out |
| Wednesday, August 15 |
| » Lost to White Sox (55-50), 5-1 | Comiskey Park I (3-4) | 51-56 | Lost 4 |
| » Starters: Pinky Woods vs Bill Dietrich | Seventh | 11½ out |
| » Lost to White Sox (56-50), 11-0 | Comiskey Park I (3-5) | 51-57 | Lost 5 |
| » Starters: Emmett O'Neill vs Orval Grove | Seventh | 11½ out |
| Thursday, August 16 |
| » Lost to White Sox (57-50), 11-3 | Comiskey Park I (3-6) | 51-58 | Lost 6 |
| » Starters: Dave Ferriss vs Thornton Lee | Seventh | 12½ out |
| Friday, August 17 |
| » Defeated White Sox (57-51), 8-2 | Comiskey Park I (4-6) | 52-58 | |
| » Starters: Otie Clark vs Johnny Humphries | Seventh | 11½ out |
| Saturday, August 18 |
| » Lost to White Sox (58-51), 16-1 | Comiskey Park I (4-7) | 52-59 | |
| » Starters: Randy Heflin vs Ed Lopat | Seventh | 11½ out |
| Sunday, August 19 |
| » Defeated Browns (55-53), 10-8 | Sportsman's Park III (2-3) | 53-59 | |
| » Starters: Dave Ferriss vs Sig Jakucki | Seventh | 11½ out |
| » Lost to Browns (56-53), 6-3 | Sportsman's Park III (2-4) | 53-60 | |
| » Starters: Pinky Woods vs Al Hollingsworth | Seventh | 11½ out |
| Monday, August 20 |
| » Lost to Browns (57-53), 10-6 | Sportsman's Park III (2-5) | 53-61 | Lost 2 |
| » Starters: Emmett O'Neill vs Tex Shirley | Seventh | 13 out |
| Tuesday, August 21 |
| » Lost to Browns (58-53), 2-1 | Sportsman's Park III (2-6) | 53-62 | Lost 3 |
| » Starters: Otie Clark vs Nels Potter | Seventh | 13 out |
| » Defeated Browns (58-54), 4-3 | Sportsman's Park III (3-6) | 54-62 | |
| » Starters: Randy Heflin vs Jack Kramer | Seventh | 13 out |
| Wednesday, August 22 |
| » Lost to Browns (59-54), 4-2 | Sportsman's Park III (3-7) | 54-63 | |
| » Starters: Pinky Woods vs Bob Muncrief | Seventh | 13½ out |
| » Defeated Browns (59-55), 5-4 | Sportsman's Park III (4-7) | 55-63 | |
| » Starters: Mike Ryba vs Lefty West | Seventh | 13½ out |
| Sunday, August 26 |
| » Defeated Athletics (36-78), 4-3 | Fenway Park (30-22) | 56-63 | Won 2 |
| » Starters: Russ Christopher vs Dave Ferriss | Seventh | 11½ out |
| » Defeated Athletics (36-79), 4-3 | Fenway Park (31-22) | 57-63 | Won 3 |
| » Starters: Jesse Flores vs Otie Clark | Seventh | 11½ out |
| Tuesday, August 28 |
| » Lost to Yankees (61-55), 8-7 | Yankee Stadium (1-6) | 57-64 | |
| » Starters: Randy Heflin vs Monk Dubiel | Seventh | 12½ out |
| Wednesday, August 29 |
| » Defeated Yankees (61-56), 1-0 | Yankee Stadium (2-6) | 58-64 | |
| » Starters: Vic Johnson vs Bill Zuber | Seventh | 11½ out |
| Thursday, August 30 |
| » Lost to Yankees (62-56), 7-1 | Yankee Stadium (2-7) | 58-65 | |
| » Starters: Dave Ferriss vs Bill Bevens | Seventh | 12 out |
| Friday, August 31 |
| » Lost to Athletics (38-81), 6-3 | Shibe Park (4-3) | 58-66 | Lost 2 |
| » Starters: Otie Clark vs Russ Christopher | Seventh | 11½ out |
| » Defeated Athletics (38-82), 4-2 | Shibe Park (5-3) | 59-66 | |
| » Starters: Randy Heflin vs Jesse Flores | Seventh | 11½ out |
| Saturday, September 1 |
| » Defeated Athletics (38-83), 7-1 | Shibe Park (6-3) | 60-66 | Won 2 |
| » Starters: Mike Ryba vs Lou Knerr | Seventh | 11½ out |
| Sunday, September 2 |
| » Lost to Athletics (39-83), 1-0 | Shibe Park (6-4) | 60-67 | |
| » Starters: Pinky Woods vs Bobo Newsom | Seventh | 12 out |
| » Lost to Athletics (40-83), 7-2 | Shibe Park (6-5) | 60-68 | Lost 2 |
| » Starters: Emmett O'Neill vs Phil Marchildon | Seventh | 12 out |
| Monday, September 3 |
| » Lost to Senators (72-57), 11-5 | Fenway Park (31-23) | 60-69 | Lost 3 |
| » Starters: Marino Pieretti vs Dave Ferriss | Seventh | 13 out |
| » Defeated Senators (72-58), 8-4 | Fenway Park (32-23) | 61-69 | |
| » Starters: Sandy Ullrich vs Vic Johnson | Seventh | 13 out |
| Wednesday, September 5 |
| » Defeated Indians (64-61), 2-1 | Fenway Park (33-23) | 62-69 | Won 2 |
| » Starters: Bob Feller vs Otie Clark | Seventh | 13½ out |
| » Lost to Indians (65-61), 5-2 | Fenway Park (33-24) | 62-70 | |
| » Starters: Allie Reynolds vs Randy Heflin | Seventh | 13½ out |
| Thursday, September 6 |
| » Defeated Indians (65-62), 9-3 | Fenway Park (34-24) | 63-70 | |
| » Starters: Ed Klieman vs Pinky Woods | Seventh | 13 out |
| Friday, September 7 |
| » Defeated Indians (65-63), 1-0 | Fenway Park (35-24) | 64-70 | Won 2 |
| » Starters: Mel Harder vs Mike Ryba | Seventh | 13 out |
| Saturday, September 8 |
| » Defeated Indians (65-64), 9-4 | Fenway Park (36-24) | 65-70 | Won 3 |
| » Starters: Jim Bagby vs Vic Johnson | Seventh | 13 out |
| Sunday, September 9 |
| » Lost to Tigers (78-56), 6-3 | Fenway Park (36-25) | 65-71 | |
| » Starters: Al Benton vs Randy Heflin | Sixth | 14 out |
| » Tied Tigers, 3-3 | Fenway Park (36-25) | 65-71 | |
| » Starters: Jim Tobin vs Otie Clark | Sixth | 14 out |
| Monday, September 10 |
| » Defeated Tigers (78-57), 9-2 | Fenway Park (37-25) | 66-71 | |
| » Starters: Les Mueller vs Dave Ferriss | Sixth | 14 out |
| » Lost to Tigers (79-57), 2-1 | Fenway Park (37-26) | 66-72 | |
| » Starters: Stubby Overmire vs Emmett O'Neill | Sixth | 14 out |
| Tuesday, September 11 |
| » Lost to Tigers (80-57), 5-0 | Fenway Park (37-27) | 66-73 | Lost 2 |
| » Starters: Dizzy Trout vs Pinky Woods | Seventh | 15 out |
| Wednesday, September 12 |
| » Lost to Browns (72-66), 9-2 | Fenway Park (37-28) | 66-74 | Lost 3 |
| » Starters: Bob Muncrief vs Mike Ryba | Seventh | 15½ out |
| Thursday, September 13 |
| » Lost to Browns (73-66), 2-1 | Fenway Park (37-29) | 66-75 | Lost 4 |
| » Starters: Nels Potter vs Vic Johnson | Seventh | 15½ out |
| Future Red Sox Rick Wise is born in Jackson, MI. |
| Friday, September 14 |
| » Lost to Browns (74-66), 4-1 | Fenway Park (37-30) | 66-76 | Lost 5 |
| » Starters: Ox Miller vs Otie Clark | Seventh | 16½ out |
| Sunday, September 16 |
| » Lost to White Sox (69-74), 5-3 | Fenway Park (37-31) | 66-77 | Lost 6 |
| » Starters: Thornton Lee vs Mike Ryba | Seventh | 18½ out |
| » Lost to White Sox (70-74), 6-1 | Fenway Park (37-32) | 66-78 | Lost 7 |
| » Starters: Orval Grove vs Dave Ferriss | Seventh | 18½ out |
| Monday, September 17 |
| » Defeated White Sox (70-75), 8-4 | Fenway Park (38-32) | 67-78 | |
| » Starters: Johnny Humphries vs Pinky Woods | Seventh | 18½ out |
| » Lost to White Sox (71-75), 4-2 | Fenway Park (38-33) | 67-79 | |
| » Starters: Frank Papish vs Emmett O'Neill | Seventh | 18½ out |
| Wednesday, September 19 |
| » Defeated Athletics (51-93), 11-10 | Fenway Park (39-33) | 68-79 | |
| » Starters: Charlie Bowles vs Vic Johnson | Seventh | 16½ out |
| » Defeated Athletics (51-94), 3-0 | Fenway Park (40-33) | 69-79 | Won 2 |
| » Starters: Charlie Gassaway vs Otie Clark | Seventh | 16½ out |
| Thursday, September 20 |
| » Defeated Athletics (51-95), 2-0 | Fenway Park (41-33) | 70-79 | Won 3 |
| » Starters: Don Black vs Randy Heflin | Seventh | 15½ out |
| Saturday, September 22 |
| » Lost to Yankees (77-70), 2-1 | Fenway Park (41-34) | 70-80 | |
| » Starters: Monk Dubiel vs Mike Ryba | Seventh | 16½ out |
| Sunday, September 23 |
| » Defeated Yankees (77-71), 6-5 | Fenway Park (42-34) | 71-80 | |
| » Starters: Spud Chandler vs Vic Johnson | Seventh | 16 out |
| » Lost to Yankees (78-71), 2-1 | Fenway Park (42-35) | 71-81 | |
| » Starters: Tiny Bonham vs Dave Ferriss | Seventh | 16 out |
| Saturday, September 29 |
| » Lost to Yankees (80-71), 5-0 | Yankee Stadium (2-8) | 71-82 | Lost 2 |
| » Starters: Vic Johnson vs Spud Chandler | Seventh | 16½ out |
| Sunday, September 30 |
| » Lost to Yankees (81-71), 12-2 | Yankee Stadium (2-9) | 71-83 | Lost 3 |
| » Starters: Randy Heflin vs Joe Page | Seventh | 17½ out |
| Sunday, December 30 |
| Future Red Sox Tom Murphy is born in Cleveland, OH. |
Game information provided by Retrosheet (www.retrosheet.org) |
