| Friday, February 4 |
| Former White Sox Dixie Davis dies in Raleigh, NC at the age of 54. |
| Wednesday, March 15 |
| Future White Sox Wayne Granger is born in Springfield, MA. |
| Sunday, April 16 |
| Former White Sox Pop Foster dies in Princeton, NJ at the age of 67. |
| Wednesday, April 19 |
| » Defeated Indians (0-1), 3-1 | Comiskey Park I (1-0) | 1-0 | |
| » Starters: Al Smith vs Orval Grove | Second | ½ out |
| » Major-league debuts: Paul O'Dea (Indians) |
| Friday, April 21 |
| » Lost to Browns (4-0), 5-3 | Sportsman's Park III (0-1) | 1-1 | |
| » Starters: Thornton Lee vs Nels Potter | Third | 2 out |
| » Major-league debuts: Red Hayworth (Browns) |
| Sunday, April 23 |
| » Lost to Browns (5-0), 5-2 | Sportsman's Park III (0-2) | 1-2 | Lost 2 |
| » Starters: Bill Dietrich vs Jack Kramer | Sixth | 4 out |
| » Lost to Browns (6-0), 4-3 | Sportsman's Park III (0-3) | 1-3 | Lost 3 |
| » Starters: Orval Grove vs Tex Shirley | Sixth | 4 out |
| Tuesday, April 25 |
| » Major-league debuts: Freddy Schmidt and Ted Wilks (Cardinals) |
| Future White Sox Ken Tatum is born in Alexandria, LA. |
| Thursday, April 27 |
| » Lost to Tigers (3-4), 2-0 | Comiskey Park I (1-1) | 1-4 | Lost 4 |
| » Starters: Hal Newhouser vs Thornton Lee | Sixth | 5½ out |
| Friday, April 28 |
| » Lost to Browns (9-0), 3-1 | Comiskey Park I (1-2) | 1-5 | Lost 5 |
| » Starters: Jack Kramer vs Bill Dietrich | Eighth | 6½ out |
| Saturday, April 29 |
| » Defeated Browns (9-1), 4-3 | Comiskey Park I (2-2) | 2-5 | |
| » Starters: Al Hollingsworth vs Buck Ross | Eighth | 5½ out |
| Sunday, April 30 |
| » Defeated Browns (9-2), 6-5 | Comiskey Park I (3-2) | 3-5 | Won 2 |
| » Starters: Bob Muncrief vs Orval Grove | Seventh | 5½ out |
| » Lost to Browns (10-2), 5-4 | Comiskey Park I (3-3) | 3-6 | |
| » Starters: Tex Shirley vs Ed Lopat | Seventh | 5½ out |
| » Major-league debuts: Ed Lopat (White Sox) |
| Monday, May 1 |
| » Lost to Indians (5-6), 9-3 | League Park II (0-1) | 3-7 | Lost 2 |
| » Starters: Thornton Lee vs Hal Kleine | Sixth | 6 out |
| Tuesday, May 2 |
| » Defeated Indians (5-7), 3-2 | League Park II (1-1) | 4-7 | |
| » Starters: Bill Dietrich vs Al Smith | Fifth | 5 out |
| Wednesday, May 3 |
| » Lost to Indians (6-7), 9-4 | League Park II (1-2) | 4-8 | |
| » Starters: Buck Ross vs Mel Harder | Sixth | 6 out |
| Thursday, May 4 |
| » Defeated Indians (6-8), 2-1 | League Park II (2-2) | 5-8 | |
| » Starters: Ed Lopat vs Vern Kennedy | Sixth | 6 out |
| Saturday, May 6 |
| » Defeated Tigers (5-10), 4-2 | Tiger Stadium (1-0) | 6-8 | Won 2 |
| » Starters: Orval Grove vs Stubby Overmire | Fifth | 5 out |
| Sunday, May 7 |
| » Defeated Tigers (5-11), 4-1 | Tiger Stadium (2-0) | 7-8 | Won 3 |
| » Starters: Bill Dietrich vs Hal Newhouser | Fourth | 4 out |
| » Defeated Tigers (5-12), 4-2 | Tiger Stadium (3-0) | 8-8 | Won 4 |
| » Starters: Thornton Lee vs Johnny Gorsica | Fourth | 4 out |
| Wednesday, May 10 |
| » Lost to Athletics (7-9), 9-0 | Shibe Park (0-1) | 8-9 | |
| » Starters: Orval Grove vs Luke Hamlin | Fifth | 4 out |
| Thursday, May 11 |
| » Defeated Athletics (7-10), 4-2 | Shibe Park (1-1) | 9-9 | |
| » Starters: Ed Lopat vs Jesse Flores | Fifth | 2½ out |
| Friday, May 12 |
| » Lost to Athletics (8-10), 4-2 | Shibe Park (1-2) | 9-10 | |
| » Starters: Buck Ross vs Bobo Newsom | Fifth | 4 out |
| Saturday, May 13 |
| » Lost to Senators (11-8), 12-2 | Griffith Stadium (0-1) | 9-11 | Lost 2 |
| » Starters: Bill Dietrich vs Roger Wolff | Sixth | 3½ out |
| Sunday, May 14 |
| » Lost to Senators (12-8), 4-0 | Griffith Stadium (0-2) | 9-12 | Lost 3 |
| » Starters: Thornton Lee vs Dutch Leonard | Fifth | 4½ out |
| » Defeated Senators (12-9), 6-4 | Griffith Stadium (1-2) | 10-12 | |
| » Starters: Orval Grove vs Early Wynn | Fifth | 4½ out |
| Monday, May 15 |
| » Lost to Yankees (14-6), 10-2 | Yankee Stadium (0-1) | 10-13 | |
| » Starters: Ed Lopat vs Monk Dubiel | Fifth | 5½ out |
| Tuesday, May 16 |
| » Defeated Yankees (14-7), 10-4 | Yankee Stadium (1-1) | 11-13 | |
| » Starters: Bill Dietrich vs Hank Borowy | Fifth | 4½ out |
| Wednesday, May 17 |
| » Defeated Yankees (14-8), 4-0 | Yankee Stadium (2-1) | 12-13 | Won 2 |
| » Starters: Orval Grove vs Joe Page | Fifth | 3½ out |
| Thursday, May 18 |
| » Defeated Yankees (14-9), 8-4 | Yankee Stadium (3-1) | 13-13 | Won 3 |
| » Starters: Buck Ross vs Tiny Bonham | Fifth | 2½ out |
| Friday, May 19 |
| » Lost to Red Sox (11-15), 3-2 | Fenway Park (0-1) | 13-14 | |
| » Starters: Ed Lopat vs Clem Hausmann | Fifth | 3 out |
| Saturday, May 20 |
| » Lost to Red Sox (12-15), 8-1 | Fenway Park (0-2) | 13-15 | Lost 2 |
| » Starters: Thornton Lee vs Joe Bowman | Fifth | 3½ out |
| Sunday, May 21 |
| » Lost to Red Sox (13-15), 4-3 | Fenway Park (0-3) | 13-16 | Lost 3 |
| » Starters: Bill Dietrich vs Tex Hughson | Seventh | 5½ out |
| » Lost to Red Sox (14-15), 9-2 | Fenway Park (0-4) | 13-17 | Lost 4 |
| » Starters: Orval Grove vs Emmett O'Neill | Seventh | 5½ out |
| Friday, May 26 |
| » Lost to Yankees (18-10), 4-0 | Comiskey Park I (3-4) | 13-18 | Lost 5 |
| » Starters: Tiny Bonham vs Orval Grove | Seventh | 6½ out |
| Saturday, May 27 |
| » Defeated Yankees (18-11), 4-3 | Comiskey Park I (4-4) | 14-18 | |
| » Starters: Monk Dubiel vs Bill Dietrich | Seventh | 5½ out |
| Sunday, May 28 |
| » Lost to Red Sox (16-18), 6-4 | Comiskey Park I (4-5) | 14-19 | |
| » Starters: Joe Bowman vs Ed Lopat | Eighth | 7½ out |
| » Lost to Red Sox (17-18), 4-2 | Comiskey Park I (4-6) | 14-20 | Lost 2 |
| » Starters: Clem Hausmann vs Thornton Lee | Eighth | 7½ out |
| Monday, May 29 |
| » Lost to Red Sox (18-18), 3-1 | Comiskey Park I (4-7) | 14-21 | Lost 3 |
| » Starters: Tex Hughson vs Buck Ross | Seventh | 7½ out |
| Tuesday, May 30 |
| » Defeated Athletics (19-18), 5-1 | Comiskey Park I (5-7) | 15-21 | |
| » Starters: Bobo Newsom vs Bill Dietrich | Seventh | 5½ out |
| » Defeated Athletics (19-19), 2-1 | Comiskey Park I (6-7) | 16-21 | Won 2 |
| » Starters: Lum Harris vs Orval Grove | Seventh | 5½ out |
| Friday, June 2 |
| » Defeated Senators (20-21), 5-2 | Comiskey Park I (7-7) | 17-21 | Won 3 |
| » Starters: Dutch Leonard vs Thornton Lee | Seventh | 5 out |
| Saturday, June 3 |
| » Defeated Senators (20-22), 5-3 | Comiskey Park I (8-7) | 18-21 | Won 4 |
| » Starters: Early Wynn vs Bill Dietrich | Sixth | 5 out |
| Sunday, June 4 |
| » Defeated Senators (20-23), 6-5 | Comiskey Park I (9-7) | 19-21 | Won 5 |
| » Starters: Johnny Niggeling vs Orval Grove | Fourth | 4 out |
| » Defeated Senators (20-24), 9-1 | Comiskey Park I (10-7) | 20-21 | Won 6 |
| » Starters: Mickey Haefner vs Ed Lopat | Fourth | 4 out |
| Wednesday, June 7 |
| » Defeated Tigers (24-23), 3-1 | Comiskey Park I (11-7) | 21-21 | Won 7 |
| » Starters: Hal Newhouser vs Orval Grove | Fourth | 3½ out |
| Future White Sox Roger Nelson is born in Altadena, CA. |
| Sunday, June 11 |
| » Defeated Tigers (24-24), 4-2 | Comiskey Park I (12-7) | 22-21 | Won 8 |
| » Starters: Dizzy Trout vs Bill Dietrich | Fourth | 3½ out |
| » Lost to Tigers (25-24), 1-0 | Comiskey Park I (12-8) | 22-22 | |
| » Starters: Stubby Overmire vs Thornton Lee | Fourth | 3½ out |
| Monday, June 12 |
| » Major-league debuts: Ralph Branca (Dodgers) |
| Tuesday, June 13 |
| » Lost to Browns (29-23), 5-3 | Comiskey Park I (12-9) | 22-23 | Lost 2 |
| » Starters: Jack Kramer vs Ed Lopat | Fifth | 3½ out |
| Wednesday, June 14 |
| » Lost to Browns (30-23), 10-3 | Comiskey Park I (12-10) | 22-24 | Lost 3 |
| » Starters: Nels Potter vs Johnny Humphries | Fifth | 4½ out |
| Friday, June 16 |
| » Defeated Indians (26-29), 3-1 | Cleveland Stadium (1-0) | 23-24 | |
| » Starters: Orval Grove vs Mel Harder | Sixth | 4½ out |
| Sunday, June 18 |
| » Defeated Indians (26-30), 3-2 | Cleveland Stadium (2-0) | 24-24 | Won 2 |
| » Starters: Bill Dietrich vs Ed Klieman | Third | 4 out |
| » Defeated Indians (26-31), 7-6 | Cleveland Stadium (3-0) | 25-24 | Won 3 |
| » Starters: Thornton Lee vs Vern Kennedy | Third | 4 out |
| Tuesday, June 20 |
| » Defeated Browns (32-26), 4-3 | Sportsman's Park III (1-3) | 26-24 | Won 4 |
| » Starters: Ed Lopat vs Bob Muncrief | Third | 4 out |
| » Lost to Browns (33-26), 5-0 | Sportsman's Park III (1-4) | 26-25 | |
| » Starters: Orval Grove vs Al Hollingsworth | Third | 4 out |
| Wednesday, June 21 |
| » Lost to Browns (34-26), 11-2 | Sportsman's Park III (1-5) | 26-26 | Lost 2 |
| » Starters: Johnny Humphries vs Nels Potter | Third | 4 out |
| Thursday, June 22 |
| » Defeated Browns (34-27), 10-3 | Sportsman's Park III (2-5) | 27-26 | |
| » Starters: Bill Dietrich vs Jack Kramer | Third | 4 out |
| Friday, June 23 |
| » Lost to Indians (29-32), 5-1 | Comiskey Park I (12-11) | 27-27 | |
| » Starters: Al Smith vs Thornton Lee | Third | 4 out |
| Saturday, June 24 |
| » Defeated Indians (29-33), 2-1 | Comiskey Park I (13-11) | 28-27 | |
| » Starters: Allie Reynolds vs Orval Grove | Third | 4 out |
| Sunday, June 25 |
| » Defeated Indians (29-34), 11-0 | Comiskey Park I (14-11) | 29-27 | Won 2 |
| » Starters: Mel Harder vs Bill Dietrich | Second | 4 out |
| » Defeated Indians (29-35), 4-3 | Comiskey Park I (15-11) | 30-27 | Won 3 |
| » Starters: Ed Klieman vs Ed Lopat | Second | 4 out |
| Wednesday, June 28 |
| » Lost to Red Sox (34-31), 4-3 | Fenway Park (0-5) | 30-28 | |
| » Starters: Orval Grove vs Joe Bowman | Fourth | 4 out |
| Thursday, June 29 |
| » Lost to Red Sox (35-31), 5-4 | Fenway Park (0-6) | 30-29 | Lost 2 |
| » Starters: Ed Lopat vs Tex Hughson | Fourth | 4 out |
| Friday, June 30 |
| » Lost to Red Sox (36-31), 11-0 | Fenway Park (0-7) | 30-30 | Lost 3 |
| » Starters: Bill Dietrich vs Oscar Judd | Fourth | 5 out |
| Saturday, July 1 |
| » Defeated Yankees (33-31), 3-2 | Yankee Stadium (4-1) | 31-30 | |
| » Starters: Johnny Humphries vs Hank Borowy | Fourth | 5 out |
| Sunday, July 2 |
| » Defeated Yankees (33-32), 7-3 | Yankee Stadium (5-1) | 32-30 | Won 2 |
| » Starters: Bill Dietrich vs Tiny Bonham | Fourth | 4 out |
| » Lost to Yankees (34-32), 7-6 | Yankee Stadium (5-2) | 32-31 | |
| » Starters: Orval Grove vs Bill Zuber | Fourth | 4 out |
| Tuesday, July 4 |
| » Lost to Senators (34-36), 2-0 | Griffith Stadium (1-3) | 32-32 | Lost 2 |
| » Starters: Thornton Lee vs Johnny Niggeling | Third | 4 out |
| » Defeated Senators (34-37), 3-2 | Griffith Stadium (2-3) | 33-32 | |
| » Starters: Ed Lopat vs Early Wynn | Third | 4 out |
| Wednesday, July 5 |
| » Lost to Senators (35-37), 3-1 | Griffith Stadium (2-4) | 33-33 | |
| » Starters: Bill Dietrich vs Dutch Leonard | Fourth | 5 out |
| Thursday, July 6 |
| » Lost to Senators (36-37), 5-0 | Griffith Stadium (2-5) | 33-34 | Lost 2 |
| » Starters: Orval Grove vs Mickey Haefner | Fourth | 6 out |
| Friday, July 7 |
| » Lost to Athletics (33-41), 4-3 | Shibe Park (1-3) | 33-35 | Lost 3 |
| » Starters: Jake Wade vs Lum Harris | Fifth | 6 out |
| Saturday, July 8 |
| » Lost to Athletics (34-41), 3-1 | Shibe Park (1-4) | 33-36 | Lost 4 |
| » Starters: Johnny Humphries vs Bobo Newsom | Fifth | 7 out |
| Sunday, July 9 |
| » Defeated Athletics (34-42), 4-3 | Shibe Park (2-4) | 34-36 | |
| » Starters: Bill Dietrich vs Luke Hamlin | Fifth | 7 out |
| » Lost to Athletics (35-42), 8-2 | Shibe Park (2-5) | 34-37 | |
| » Starters: Orval Grove vs Jesse Flores | Fifth | 7 out |
| Thursday, July 13 |
| » Lost to Tigers (37-42), 9-1 | Tiger Stadium (3-1) | 34-38 | Lost 2 |
| » Starters: Orval Grove vs Dizzy Trout | Sixth | 7½ out |
| Friday, July 14 |
| » Lost to Tigers (38-42), 2-0 | Tiger Stadium (3-2) | 34-39 | Lost 3 |
| » Starters: Bill Dietrich vs Stubby Overmire | Eighth | 7½ out |
| Saturday, July 15 |
| » Defeated Tigers (38-43), 5-4 | Tiger Stadium (4-2) | 35-39 | |
| » Starters: Buck Ross vs Hal Newhouser | Seventh | 7 out |
| » Lost to Tigers (39-43), 8-2 | Tiger Stadium (4-3) | 35-40 | |
| » Starters: Ed Lopat vs Joe Orrell | Seventh | 7 out |
| Sunday, July 16 |
| » Defeated Tigers (39-44), 7-2 | Tiger Stadium (5-3) | 36-40 | |
| » Starters: Jake Wade vs Rufe Gentry | Sixth | 8 out |
| » Lost to Tigers (40-44), 7-3 | Tiger Stadium (5-4) | 36-41 | |
| » Starters: Johnny Humphries vs Dizzy Trout | Sixth | 8 out |
| Tuesday, July 18 |
| » Lost to Red Sox (44-40), 4-2 | Comiskey Park I (15-12) | 36-42 | Lost 2 |
| » Starters: Tex Hughson vs Bill Dietrich | Sixth | 9 out |
| Wednesday, July 19 |
| » Defeated Red Sox (44-41), 5-4 | Comiskey Park I (16-12) | 37-42 | |
| » Starters: Joe Bowman vs Orval Grove | Sixth | 8 out |
| Thursday, July 20 |
| » Lost to Red Sox (45-41), 11-7 | Comiskey Park I (16-13) | 37-43 | |
| » Starters: Frank Barrett vs Jake Wade | Sixth | 9 out |
| Friday, July 21 |
| » Defeated Red Sox (45-42), 5-3 | Comiskey Park I (17-13) | 38-43 | |
| » Starters: Yank Terry vs Buck Ross | Sixth | 8 out |
| Saturday, July 22 |
| » Defeated Yankees (45-39), 9-3 | Comiskey Park I (18-13) | 39-43 | Won 2 |
| » Starters: Monk Dubiel vs Johnny Humphries | Seventh | 6½ out |
| » Defeated Yankees (45-40), 4-1 | Comiskey Park I (19-13) | 40-43 | Won 3 |
| » Starters: Bill Zuber vs Ed Lopat | Seventh | 6½ out |
| Future White Sox Sparky Lyle is born in DuBois, PA. |
| Sunday, July 23 |
| » Lost to Yankees (46-40), 7-6 | Comiskey Park I (19-14) | 40-44 | |
| » Starters: Steve Roser vs Bill Dietrich | Sixth | 6½ out |
| » Defeated Yankees (46-41), 10-6 | Comiskey Park I (20-14) | 41-44 | |
| » Starters: Joe Page vs Orval Grove | Sixth | 6½ out |
| Monday, July 24 |
| » Lost to Yankees (47-41), 11-5 | Comiskey Park I (20-15) | 41-45 | |
| » Starters: Tiny Bonham vs Buck Ross | Sixth | 7½ out |
| Tuesday, July 25 |
| » Defeated Senators (42-49), 9-6 | Comiskey Park I (21-15) | 42-45 | |
| » Starters: Mickey Haefner vs Bill Dietrich | Sixth | 7½ out |
| Future White Sox Buddy Bradford is born in Mobile, AL. |
| Wednesday, July 26 |
| » Defeated Senators (42-50), 4-3 | Comiskey Park I (22-15) | 43-45 | Won 2 |
| » Starters: Johnny Niggeling vs Johnny Humphries | Sixth | 7½ out |
| Thursday, July 27 |
| » Defeated Senators (42-51), 4-0 | Comiskey Park I (23-15) | 44-45 | Won 3 |
| » Starters: Dutch Leonard vs Orval Grove | Fifth | 6½ out |
| Friday, July 28 |
| » Defeated Senators (42-52), 8-2 | Comiskey Park I (24-15) | 45-45 | Won 4 |
| » Starters: Bill LeFebvre vs Ed Lopat | Fifth | 6½ out |
| Saturday, July 29 |
| » Lost to Athletics (41-54), 6-4 | Comiskey Park I (24-16) | 45-46 | |
| » Starters: Bobo Newsom vs Jake Wade | Fifth | 7 out |
| Sunday, July 30 |
| » Defeated Athletics (41-55), 6-4 | Comiskey Park I (25-16) | 46-46 | |
| » Starters: Lum Harris vs Bill Dietrich | Fifth | 8 out |
| » Lost to Athletics (42-55), 3-0 | Comiskey Park I (25-17) | 46-47 | |
| » Starters: Jesse Flores vs Johnny Humphries | Fifth | 8 out |
| Future White Sox Pat Kelly is born in Philadelphia, PA. |
| Monday, July 31 |
| » Lost to Athletics (43-55), 3-2 | Comiskey Park I (25-18) | 46-48 | Lost 2 |
| » Starters: Russ Christopher vs Orval Grove | Sixth | 9 out |
| Tuesday, August 1 |
| » Lost to Athletics (44-55), 2-1 | Comiskey Park I (25-19) | 46-49 | Lost 3 |
| » Starters: Luke Hamlin vs Joe Haynes | Sixth | 10 out |
| Wednesday, August 2 |
| » Lost to Athletics (45-55), 9-3 | Comiskey Park I (25-20) | 46-50 | Lost 4 |
| » Starters: Lum Harris vs Ed Lopat | Sixth | 10 out |
| » Defeated Athletics (45-56), 7-3 | Comiskey Park I (26-20) | 47-50 | |
| » Starters: Don Black vs Johnny Humphries | Sixth | 10 out |
| Thursday, August 3 |
| » Defeated Indians (51-50), 3-2 | Comiskey Park I (27-20) | 48-50 | Won 2 |
| » Starters: Al Smith vs Bill Dietrich | Fifth | 9 out |
| » Defeated Indians (51-51), 5-1 | Comiskey Park I (28-20) | 49-50 | Won 3 |
| » Starters: Allie Reynolds vs Orval Grove | Fifth | 9 out |
| Friday, August 4 |
| » Defeated Indians (51-52), 5-3 | Comiskey Park I (29-20) | 50-50 | Won 4 |
| » Starters: Mel Harder vs Buck Ross | Fourth | 8½ out |
| Saturday, August 5 |
| » Lost to Tigers (50-50), 5-3 | Comiskey Park I (29-21) | 50-51 | |
| » Starters: Hal Newhouser vs Joe Haynes | Fifth | 9½ out |
| Sunday, August 6 |
| » Lost to Tigers (51-50), 10-3 | Comiskey Park I (29-22) | 50-52 | Lost 2 |
| » Starters: Stubby Overmire vs Bill Dietrich | Fifth | 11½ out |
| » Lost to Tigers (52-50), 3-1 | Comiskey Park I (29-23) | 50-53 | Lost 3 |
| » Starters: Dizzy Trout vs Orval Grove | Fifth | 11½ out |
| Wednesday, August 9 |
| » Lost to Red Sox (56-48), 9-1 | Fenway Park (0-8) | 50-54 | Lost 4 |
| » Starters: Bill Dietrich vs Tex Hughson | Sixth | 12½ out |
| Thursday, August 10 |
| » Lost to Red Sox (57-48), 2-1 | Fenway Park (0-9) | 50-55 | Lost 5 |
| » Starters: Joe Haynes vs Emmett O'Neill | Sixth | 13½ out |
| Friday, August 11 |
| » Defeated Red Sox (57-49), 9-7 | Fenway Park (1-9) | 51-55 | |
| » Starters: Johnny Humphries vs Yank Terry | Sixth | 12½ out |
| Saturday, August 12 |
| » Lost to Red Sox (58-49), 5-4 | Fenway Park (1-10) | 51-56 | |
| » Starters: Ed Lopat vs Joe Bowman | Sixth | 13½ out |
| Sunday, August 13 |
| » Lost to Yankees (55-51), 10-1 | Yankee Stadium (5-3) | 51-57 | Lost 2 |
| » Starters: Bill Dietrich vs Mel Queen | Fifth | 13½ out |
| » Defeated Yankees (55-52), 11-3 | Yankee Stadium (6-3) | 52-57 | |
| » Starters: Orval Grove vs Hank Borowy | Fifth | 13½ out |
| Monday, August 14 |
| » Lost to Yankees (56-52), 2-1 | Yankee Stadium (6-4) | 52-58 | |
| » Starters: Johnny Humphries vs Tiny Bonham | Fifth | 13½ out |
| Tuesday, August 15 |
| » Lost to Yankees (57-52), 3-1 | Yankee Stadium (6-5) | 52-59 | Lost 2 |
| » Starters: Joe Haynes vs Bill Zuber | Sixth | 14½ out |
| Wednesday, August 16 |
| » Defeated Senators (47-65), 7-2 | Griffith Stadium (3-5) | 53-59 | |
| » Starters: Ed Lopat vs Johnny Niggeling | Fifth | 13½ out |
| » Major-league debuts: Eddie Yost (Senators) |
| Thursday, August 17 |
| » Defeated Senators (47-66), 1-0 | Griffith Stadium (4-5) | 54-59 | Won 2 |
| » Starters: Bill Dietrich vs Mickey Haefner | Fourth | 13½ out |
| Friday, August 18 |
| » Defeated Senators (47-67), 2-1 | Griffith Stadium (5-5) | 55-59 | Won 3 |
| » Starters: Johnny Humphries vs Roger Wolff | Fifth | 12½ out |
| Saturday, August 19 |
| » Lost to Senators (48-67), 3-2 | Griffith Stadium (5-6) | 55-60 | |
| » Starters: Jake Wade vs Alex Carrasquel | Fifth | 12½ out |
| Sunday, August 20 |
| » Defeated Athletics (54-65), 3-2 | Shibe Park (3-5) | 56-60 | |
| » Starters: Joe Haynes vs Bobo Newsom | Fifth | 11½ out |
| » Lost to Athletics (55-65), 8-3 | Shibe Park (3-6) | 56-61 | |
| » Starters: Ed Lopat vs Luke Hamlin | Fifth | 11½ out |
| Monday, August 21 |
| » Lost to Athletics (56-65), 3-2 | Shibe Park (3-7) | 56-62 | Lost 2 |
| » Starters: Bill Dietrich vs Don Black | Fifth | 12½ out |
| Tuesday, August 22 |
| » Lost to Athletics (57-65), 5-1 | Shibe Park (3-8) | 56-63 | Lost 3 |
| » Starters: Johnny Humphries vs Russ Christopher | Fifth | 12½ out |
| Friday, August 25 |
| » Lost to Indians (58-65), 10-2 | Cleveland Stadium (3-1) | 56-64 | Lost 4 |
| » Starters: Bill Dietrich vs Mel Harder | Seventh | 12½ out |
| Saturday, August 26 |
| » Defeated Indians (58-66), 6-5 | League Park II (3-2) | 57-64 | |
| » Starters: Ed Lopat vs Al Smith | Sixth | 11½ out |
| Sunday, August 27 |
| » Lost to Indians (59-66), 4-3 | Cleveland Stadium (3-2) | 57-65 | |
| » Starters: Joe Haynes vs Jim Bagby | Seventh | 12½ out |
| » Lost to Indians (60-66), 1-0 | Cleveland Stadium (3-3) | 57-66 | Lost 2 |
| » Starters: Johnny Humphries vs Steve Gromek | Seventh | 12½ out |
| Tuesday, August 29 |
| » Lost to Tigers (66-57), 7-0 | Tiger Stadium (5-5) | 57-67 | Lost 3 |
| » Starters: Bill Dietrich vs Dizzy Trout | Seventh | 13½ out |
| Wednesday, August 30 |
| » Defeated Tigers (66-58), 8-3 | Tiger Stadium (6-5) | 58-67 | |
| » Starters: Ed Lopat vs Johnny Gorsica | Seventh | 12½ out |
| Friday, September 1 |
| » Defeated Indians (61-68), 5-4 | Comiskey Park I (30-23) | 59-67 | Won 2 |
| » Starters: Al Smith vs Joe Haynes | Seventh | 11 out |
| Saturday, September 2 |
| » Lost to Indians (62-68), 5-2 | Comiskey Park I (30-24) | 59-68 | |
| » Starters: Jim Bagby vs Johnny Humphries | Seventh | 11 out |
| Sunday, September 3 |
| » Lost to Indians (63-68), 4-1 | Comiskey Park I (30-25) | 59-69 | Lost 2 |
| » Starters: Steve Gromek vs Bill Dietrich | Seventh | 12 out |
| Monday, September 4 |
| » Lost to Tigers (70-59), 12-2 | Comiskey Park I (30-26) | 59-70 | Lost 3 |
| » Starters: Stubby Overmire vs Orval Grove | Seventh | 12½ out |
| » Defeated Tigers (70-60), 6-3 | Comiskey Park I (31-26) | 60-70 | |
| » Starters: Johnny Gorsica vs Ed Lopat | Seventh | 12½ out |
| Tuesday, September 5 |
| » Lost to Tigers (71-60), 6-0 | Comiskey Park I (31-27) | 60-71 | |
| » Starters: Hal Newhouser vs Joe Haynes | Seventh | 13 out |
| Wednesday, September 6 |
| » Lost to Tigers (72-60), 3-2 | Comiskey Park I (31-28) | 60-72 | Lost 2 |
| » Starters: Rufe Gentry vs Johnny Humphries | Seventh | 13½ out |
| Thursday, September 7 |
| » Lost to Browns (74-59), 5-4 | Comiskey Park I (31-29) | 60-73 | Lost 3 |
| » Starters: Denny Galehouse vs Orval Grove | Sixth | 14 out |
| Friday, September 8 |
| » Defeated Browns (74-60), 9-5 | Comiskey Park I (32-29) | 61-73 | |
| » Starters: Bob Muncrief vs Bill Dietrich | Seventh | 14 out |
| Saturday, September 9 |
| » Defeated Browns (74-61), 2-1 | Comiskey Park I (33-29) | 62-73 | Won 2 |
| » Starters: Jack Kramer vs Ed Lopat | Seventh | 13 out |
| Sunday, September 10 |
| » Lost to Browns (75-61), 6-2 | Comiskey Park I (33-30) | 62-74 | |
| » Starters: Nels Potter vs Johnny Humphries | Sixth | 13 out |
| » Defeated Browns (75-62), 3-2 | Comiskey Park I (34-30) | 63-74 | |
| » Starters: Sig Jakucki vs Joe Haynes | Sixth | 13 out |
| Friday, September 15 |
| » Lost to Browns (76-62), 5-1 | Sportsman's Park III (2-6) | 63-75 | |
| » Starters: Orval Grove vs Denny Galehouse | Sixth | 13½ out |
| Saturday, September 16 |
| » Lost to Browns (77-62), 9-0 | Sportsman's Park III (2-7) | 63-76 | Lost 2 |
| » Starters: Ed Lopat vs Jack Kramer | Sixth | 14 out |
| Future White Sox Chuck Brinkman is born in Cincinnati, OH. |
| Sunday, September 17 |
| » Lost to Browns (78-62), 5-1 | Sportsman's Park III (2-8) | 63-77 | Lost 3 |
| » Starters: Bill Dietrich vs Nels Potter | Seventh | 14½ out |
| » Defeated Browns (78-63), 8-2 | Sportsman's Park III (3-8) | 64-77 | |
| » Starters: Joe Haynes vs Bob Muncrief | Seventh | 14½ out |
| Tuesday, September 19 |
| » Defeated Athletics (67-76), 6-3 | Comiskey Park I (35-30) | 65-77 | Won 2 |
| » Starters: Jesse Flores vs Johnny Humphries | Seventh | 14½ out |
| Wednesday, September 20 |
| » Defeated Athletics (67-77), 6-1 | Comiskey Park I (36-30) | 66-77 | Won 3 |
| » Starters: Russ Christopher vs Orval Grove | Seventh | 14½ out |
| Saturday, September 23 |
| » Defeated Senators (61-84), 5-4 | Comiskey Park I (37-30) | 67-77 | Won 4 |
| » Starters: Baby Ortiz vs Bill Dietrich | Sixth | 15 out |
| » Major-league debuts: George Binks and Baby Ortiz (Senators) |
| Sunday, September 24 |
| » Defeated Senators (61-85), 9-3 | Comiskey Park I (38-30) | 68-77 | Won 5 |
| » Starters: Roger Wolff vs Thornton Lee | Sixth | 14½ out |
| » Defeated Senators (61-86), 2-0 | Comiskey Park I (39-30) | 69-77 | Won 6 |
| » Starters: Vern Curtis vs Ed Lopat | Sixth | 14½ out |
| Monday, September 25 |
| » Lost to Yankees (80-67), 3-1 | Comiskey Park I (39-31) | 69-78 | |
| » Starters: Mel Queen vs Orval Grove | Fifth | 15 out |
| » Lost to Yankees (81-67), 5-4 | Comiskey Park I (39-32) | 69-79 | Lost 2 |
| » Starters: Monk Dubiel vs Joe Haynes | Fifth | 15 out |
| Tuesday, September 26 |
| » Lost to Yankees (82-67), 9-5 | Comiskey Park I (39-33) | 69-80 | Lost 3 |
| » Starters: Bill Zuber vs Johnny Humphries | Fifth | 16 out |
| Wednesday, September 27 |
| » Lost to Yankees (83-67), 7-2 | Comiskey Park I (39-34) | 69-81 | Lost 4 |
| » Starters: Bill Bevens vs Bill Dietrich | Sixth | 17 out |
| Friday, September 29 |
| » Defeated Red Sox (75-76), 4-3 | Comiskey Park I (40-34) | 70-81 | |
| » Starters: Clem Dreisewerd vs Thornton Lee | Fifth | 16½ out |
| Saturday, September 30 |
| » Lost to Red Sox (76-76), 11-2 | Comiskey Park I (40-35) | 70-82 | |
| » Starters: Joe Bowman vs Orval Grove | Fifth | 17½ out |
| Sunday, October 1 |
| » Lost to Red Sox (77-76), 3-1 | Comiskey Park I (40-36) | 70-83 | Lost 2 |
| » Starters: Rex Cecil vs Joe Haynes | Sixth | 18 out |
| » Defeated Red Sox (77-77), 4-1 | Comiskey Park I (41-36) | 71-83 | |
| » Starters: Pinky Woods vs Johnny Humphries | Sixth | 18 out |
| Tuesday, October 24 |
| Future White Sox John Jeter is born in Shreveport, LA. |
| Friday, November 17 |
| Future White Sox Tom Seaver is born in Fresno, CA. |
| Sunday, December 10 |
| Future White Sox Steve Renko is born in Kansas City, KS. |
| Friday, December 15 |
| Future White Sox Stan Bahnsen is born in Council Bluffs, IA. |
| Monday, December 18 |
| Future White Sox Syd O'Brien is born in Compton, CA. |
| Friday, December 22 |
| Future White Sox Steve Carlton is born in Miami, FL. |
Game information provided by Retrosheet (www.retrosheet.org) |