| Friday, January 7 |
| Former Senator George Mullin dies in Wabash, IN at the age of 64. |
| Thursday, January 13 |
| Former Senator Kid Elberfeld dies in Chattanooga, TN at the age of 69. |
| Thursday, February 17 |
| Future Senator Dick Bosman is born in Kenosha, WI. |
| Wednesday, March 29 |
| Future Senator Denny McLain is born in Chicago, IL. |
| Friday, April 14 |
| Future Senator Frank Bertaina is born in San Francisco, CA. |
| Sunday, April 16 |
| Former Senator Pop Foster dies in Princeton, NJ at the age of 67. |
| Tuesday, April 18 |
| » Lost to Athletics (1-0), 3-2 | Griffith Stadium (0-1) | 0-1 | |
| » Starters: Lum Harris vs Johnny Niggeling | Third | 1 out |
| Wednesday, April 19 |
| » Major-league debuts: Al Lyons (Tigers) |
| Thursday, April 20 |
| » Defeated Athletics (1-1), 5-0 | Griffith Stadium (1-1) | 1-1 | |
| » Starters: Russ Christopher vs Early Wynn | Fourth | 1½ out |
| Former Senator Elmer Gedeon dies in St.Pol, France at the age of 28. |
| Friday, April 21 |
| » Major-league debuts: Red Hayworth (Browns) |
| Saturday, April 22 |
| » Lost to Yankees (2-2), 6-3 | Yankee Stadium (0-1) | 1-2 | |
| » Starters: Roger Wolff vs Spud Chandler | Fifth | 2½ out |
| Tuesday, April 25 |
| » Lost to Red Sox (3-2), 5-4 | Griffith Stadium (1-2) | 1-3 | Lost 2 |
| » Starters: Emmett O'Neill vs Johnny Niggeling | Sixth | 4 out |
| Wednesday, April 26 |
| » Defeated Red Sox (3-3), 2-1 | Griffith Stadium (2-2) | 2-3 | |
| » Starters: Yank Terry vs Early Wynn | Fourth | 4 out |
| Saturday, April 29 |
| » Defeated Yankees (3-4), 9-3 | Griffith Stadium (3-2) | 3-3 | Won 2 |
| » Starters: Atley Donald vs Dutch Leonard | Third | 4 out |
| Sunday, April 30 |
| » Lost to Yankees (4-4), 2-1 | Griffith Stadium (3-3) | 3-4 | |
| » Starters: Tiny Bonham vs Mickey Haefner | Fifth | 5 out |
| » Lost to Yankees (5-4), 3-2 | Griffith Stadium (3-4) | 3-5 | Lost 2 |
| » Starters: Joe Page vs Early Wynn | Fifth | 5 out |
| Monday, May 1 |
| » Defeated Red Sox (5-6), 11-4 | Fenway Park (1-0) | 4-5 | |
| » Starters: Roger Wolff vs Yank Terry | Fourth | 4½ out |
| » Major-league debuts: Joe Wood (Red Sox) |
| Tuesday, May 2 |
| » Defeated Red Sox (5-7), 5-2 | Fenway Park (2-0) | 5-5 | Won 2 |
| » Starters: Johnny Niggeling vs Pinky Woods | Third | 3½ out |
| Wednesday, May 3 |
| » Lost to Red Sox (6-7), 11-10 | Fenway Park (2-1) | 5-6 | |
| » Starters: Dutch Leonard vs Vic Johnson | Fourth | 4½ out |
| » Major-league debuts: Sandy Ullrich (Senators) |
| Friday, May 5 |
| » Defeated Athletics (5-7), 11-8 | Shibe Park (1-0) | 6-6 | |
| » Starters: Early Wynn vs Jesse Flores | Third | 4½ out |
| » Major-league debuts: Preston Gomez (Senators) |
| Saturday, May 6 |
| » Defeated Athletics (5-8), 5-0 | Shibe Park (2-0) | 7-6 | Won 2 |
| » Starters: Mickey Haefner vs Don Black | Third | 3½ out |
| Sunday, May 7 |
| » Defeated Athletics (5-9), 2-1 | Shibe Park (3-0) | 8-6 | Won 3 |
| » Starters: Roger Wolff vs Bobo Newsom | Third | 3½ out |
| » Lost to Athletics (6-9), 7-3 | Shibe Park (3-1) | 8-7 | |
| » Starters: Alex Carrasquel vs Lum Harris | Third | 3½ out |
| Wednesday, May 10 |
| » Defeated Browns (13-6), 5-1 | Griffith Stadium (4-4) | 9-7 | |
| » Starters: Nels Potter vs Johnny Niggeling | Third | 2½ out |
| Thursday, May 11 |
| » Defeated Browns (13-7), 4-2 | Griffith Stadium (5-4) | 10-7 | Won 2 |
| » Starters: Jack Kramer vs Mickey Haefner | Third | 1 out |
| Friday, May 12 |
| » Lost to Browns (14-7), 6-4 | Griffith Stadium (5-5) | 10-8 | |
| » Starters: Bob Muncrief vs Early Wynn | Third | 2½ out |
| Saturday, May 13 |
| » Defeated White Sox (9-11), 12-2 | Griffith Stadium (6-5) | 11-8 | |
| » Starters: Bill Dietrich vs Roger Wolff | Third | 1 out |
| Sunday, May 14 |
| » Defeated White Sox (9-12), 4-0 | Griffith Stadium (7-5) | 12-8 | Won 2 |
| » Starters: Thornton Lee vs Dutch Leonard | Third | 2 out |
| » Lost to White Sox (10-12), 6-4 | Griffith Stadium (7-6) | 12-9 | |
| » Starters: Orval Grove vs Early Wynn | Third | 2 out |
| Monday, May 15 |
| » Defeated Indians (10-14), 4-3 | Griffith Stadium (8-6) | 13-9 | |
| » Starters: Mel Harder vs Johnny Niggeling | Second | 2 out |
| Tuesday, May 16 |
| » Defeated Indians (10-15), 3-2 | Griffith Stadium (9-6) | 14-9 | Won 2 |
| » Starters: Allie Reynolds vs Mickey Haefner | Second | 1 out |
| Wednesday, May 17 |
| » Lost to Indians (11-15), 4-2 | Griffith Stadium (9-7) | 14-10 | |
| » Starters: Vern Kennedy vs Roger Wolff | Third | 1 out |
| Thursday, May 18 |
| » Defeated Indians (11-16), 4-2 | Griffith Stadium (10-7) | 15-10 | |
| » Starters: Hal Kleine vs Dutch Leonard | Second | 1 out |
| Friday, May 19 |
| » Lost to Tigers (12-16), 4-1 | Griffith Stadium (10-8) | 15-11 | |
| » Starters: Johnny Gorsica vs Early Wynn | Third | 1½ out |
| Saturday, May 20 |
| » Lost to Tigers (13-16), 6-2 | Griffith Stadium (10-9) | 15-12 | Lost 2 |
| » Starters: Stubby Overmire vs Mickey Haefner | Third | 1 out |
| Sunday, May 21 |
| » Lost to Tigers (14-16), 2-1 | Griffith Stadium (10-10) | 15-13 | Lost 3 |
| » Starters: Dizzy Trout vs Johnny Niggeling | Third | 3 out |
| » Lost to Tigers (15-16), 7-1 | Griffith Stadium (10-11) | 15-14 | Lost 4 |
| » Starters: Hal Newhouser vs Roger Wolff | Third | 3 out |
| Wednesday, May 24 |
| » Defeated Indians (14-18), 5-4 | League Park II (1-0) | 16-14 | |
| » Starters: Dutch Leonard vs Al Smith | Third | 2½ out |
| Thursday, May 25 |
| » Defeated Indians (14-19), 4-2 | Cleveland Stadium (1-0) | 17-14 | Won 2 |
| » Starters: Mickey Haefner vs Mel Harder | Third | 2 out |
| Friday, May 26 |
| » Defeated Indians (14-20), 5-3 | League Park II (2-0) | 18-14 | Won 3 |
| » Starters: Early Wynn vs Vern Kennedy | Second | 2 out |
| Saturday, May 27 |
| » Lost to Indians (15-20), 5-4 | League Park II (2-1) | 18-15 | |
| » Starters: Roger Wolff vs Hal Kleine | Third | 2 out |
| Sunday, May 28 |
| » Defeated Tigers (16-20), 4-2 | Tiger Stadium (1-0) | 19-15 | |
| » Starters: Johnny Niggeling vs Stubby Overmire | Second | 3 out |
| » Lost to Tigers (17-20), 15-2 | Tiger Stadium (1-1) | 19-16 | |
| » Starters: Milo Candini vs Rufe Gentry | Second | 3 out |
| Monday, May 29 |
| » Lost to Tigers (18-20), 2-1 | Tiger Stadium (1-2) | 19-17 | Lost 2 |
| » Starters: Dutch Leonard vs Johnny Gorsica | Third | 3 out |
| Tuesday, May 30 |
| » Lost to Browns (22-18), 6-4 | Sportsman's Park III (0-1) | 19-18 | Lost 3 |
| » Starters: Mickey Haefner vs Nels Potter | Third | 3 out |
| » Lost to Browns (23-18), 4-2 | Sportsman's Park III (0-2) | 19-19 | Lost 4 |
| » Starters: Early Wynn vs Tex Shirley | Third | 3 out |
| Wednesday, May 31 |
| » Lost to Browns (24-18), 4-3 | Sportsman's Park III (0-3) | 19-20 | Lost 5 |
| » Starters: Roger Wolff vs Sig Jakucki | Fifth | 3½ out |
| Thursday, June 1 |
| » Defeated Browns (24-19), 11-5 | Sportsman's Park III (1-3) | 20-20 | |
| » Starters: Bill LeFebvre vs Jack Kramer | Fifth | 2½ out |
| Friday, June 2 |
| » Lost to White Sox (17-21), 5-2 | Comiskey Park I (0-1) | 20-21 | |
| » Starters: Dutch Leonard vs Thornton Lee | Fourth | 3½ out |
| Saturday, June 3 |
| » Lost to White Sox (18-21), 5-3 | Comiskey Park I (0-2) | 20-22 | Lost 2 |
| » Starters: Early Wynn vs Bill Dietrich | Fourth | 4½ out |
| Sunday, June 4 |
| » Lost to White Sox (19-21), 6-5 | Comiskey Park I (0-3) | 20-23 | Lost 3 |
| » Starters: Johnny Niggeling vs Orval Grove | Eighth | 5½ out |
| » Lost to White Sox (20-21), 9-1 | Comiskey Park I (0-4) | 20-24 | Lost 4 |
| » Starters: Mickey Haefner vs Ed Lopat | Eighth | 5½ out |
| Thursday, June 8 |
| » Defeated Athletics (20-23), 7-5 | Shibe Park (4-1) | 21-24 | |
| » Starters: Dutch Leonard vs Don Black | Seventh | 4½ out |
| Friday, June 9 |
| » Defeated Athletics (20-24), 2-1 | Shibe Park (5-1) | 22-24 | Won 2 |
| » Starters: Early Wynn vs Russ Christopher | Seventh | 3½ out |
| Sunday, June 11 |
| » Lost to Athletics (21-24), 6-1 | Shibe Park (5-2) | 22-25 | |
| » Starters: Mickey Haefner vs Bobo Newsom | Seventh | 4½ out |
| » Lost to Athletics (22-24), 6-5 | Shibe Park (5-3) | 22-26 | Lost 2 |
| » Starters: Roger Wolff vs Lum Harris | Seventh | 4½ out |
| Monday, June 12 |
| » Defeated Yankees (22-23), 4-3 | Griffith Stadium (11-11) | 23-26 | |
| » Starters: Joe Page vs Johnny Niggeling | Eighth | 4 out |
| Tuesday, June 13 |
| » Defeated Yankees (22-24), 3-0 | Griffith Stadium (12-11) | 24-26 | Won 2 |
| » Starters: Bill Zuber vs Dutch Leonard | Sixth | 4 out |
| Wednesday, June 14 |
| » Lost to Yankees (23-24), 6-2 | Griffith Stadium (12-12) | 24-27 | |
| » Starters: Monk Dubiel vs Early Wynn | Seventh | 5 out |
| Thursday, June 15 |
| » Defeated Yankees (23-25), 3-2 | Griffith Stadium (13-12) | 25-27 | |
| » Starters: Joe Page vs Mickey Haefner | Fourth | 4½ out |
| Friday, June 16 |
| » Defeated Red Sox (29-24), 4-0 | Griffith Stadium (14-12) | 26-27 | Won 2 |
| » Starters: Clem Hausmann vs Milo Candini | Fourth | 4½ out |
| Saturday, June 17 |
| » Lost to Red Sox (30-24), 11-4 | Griffith Stadium (14-13) | 26-28 | |
| » Starters: Joe Bowman vs Roger Wolff | Sixth | 5½ out |
| » Major-league debuts: Gene Patton (Red Sox) |
| Sunday, June 18 |
| » Lost to Red Sox (31-24), 9-6 | Griffith Stadium (14-14) | 26-29 | Lost 2 |
| » Starters: Oscar Judd vs Dutch Leonard | Fifth | 4½ out |
| » Defeated Red Sox (31-25), 1-0 | Griffith Stadium (15-14) | 27-29 | |
| » Starters: Pinky Woods vs Early Wynn | Fifth | 4½ out |
| Tuesday, June 20 |
| » Lost to Yankees (26-28), 3-1 | Yankee Stadium (0-2) | 27-30 | |
| » Starters: Johnny Niggeling vs Hank Borowy | Sixth | 5 out |
| Future Senator Dave Nelson is born in Fort Sill, OK. |
| Wednesday, June 21 |
| » Lost to Yankees (27-28), 4-3 | Yankee Stadium (0-3) | 27-31 | Lost 2 |
| » Starters: Mickey Haefner vs Atley Donald | Seventh | 5½ out |
| » Defeated Yankees (27-29), 6-4 | Yankee Stadium (1-3) | 28-31 | |
| » Starters: Milo Candini vs Joe Page | Seventh | 5½ out |
| Thursday, June 22 |
| » Lost to Yankees (28-29), 4-0 | Yankee Stadium (1-4) | 28-32 | |
| » Starters: Dutch Leonard vs Bill Zuber | Seventh | 5½ out |
| Friday, June 23 |
| » Defeated Red Sox (32-30), 7-1 | Fenway Park (3-1) | 29-32 | |
| » Starters: Early Wynn vs Vic Johnson | Sixth | 5½ out |
| Sunday, June 25 |
| » Defeated Red Sox (32-31), 5-4 | Fenway Park (4-1) | 30-32 | Won 2 |
| » Starters: Roger Wolff vs Clem Hausmann | Fifth | 7 out |
| » Lost to Red Sox (33-31), 4-0 | Fenway Park (4-2) | 30-33 | |
| » Starters: Milo Candini vs Tex Hughson | Fifth | 7 out |
| Wednesday, June 28 |
| » Defeated Tigers (30-35), 4-1 | Griffith Stadium (16-14) | 31-33 | |
| » Starters: Rufe Gentry vs Johnny Niggeling | Fifth | 6 out |
| Thursday, June 29 |
| » Lost to Tigers (31-35), 4-0 | Griffith Stadium (16-15) | 31-34 | |
| » Starters: Hal Newhouser vs Early Wynn | Fifth | 6 out |
| Friday, June 30 |
| » Defeated Tigers (31-36), 4-2 | Griffith Stadium (17-15) | 32-34 | |
| » Starters: Johnny Gorsica vs Milo Candini | Fifth | 6 out |
| Saturday, July 1 |
| » Defeated Indians (31-37), 4-2 | Griffith Stadium (18-15) | 33-34 | Won 2 |
| » Starters: Mel Harder vs Dutch Leonard | Fifth | 6 out |
| Sunday, July 2 |
| » Lost to Indians (32-37), 4-3 | Griffith Stadium (18-16) | 33-35 | |
| » Starters: Ed Klieman vs Mickey Haefner | Fifth | 6 out |
| » Lost to Indians (33-37), 6-3 | Griffith Stadium (18-17) | 33-36 | Lost 2 |
| » Starters: Steve Gromek vs Bill LeFebvre | Fifth | 6 out |
| Tuesday, July 4 |
| » Defeated White Sox (32-32), 2-0 | Griffith Stadium (19-17) | 34-36 | |
| » Starters: Thornton Lee vs Johnny Niggeling | Sixth | 6 out |
| » Lost to White Sox (33-32), 3-2 | Griffith Stadium (19-18) | 34-37 | |
| » Starters: Ed Lopat vs Early Wynn | Sixth | 6 out |
| Wednesday, July 5 |
| » Defeated White Sox (33-33), 3-1 | Griffith Stadium (20-18) | 35-37 | |
| » Starters: Bill Dietrich vs Dutch Leonard | Fifth | 6 out |
| Thursday, July 6 |
| » Defeated White Sox (33-34), 5-0 | Griffith Stadium (21-18) | 36-37 | Won 2 |
| » Starters: Orval Grove vs Mickey Haefner | Fifth | 6 out |
| Friday, July 7 |
| » Defeated Browns (43-33), 7-0 | Griffith Stadium (22-18) | 37-37 | Won 3 |
| » Starters: Jack Kramer vs Milo Candini | Fourth | 5 out |
| Saturday, July 8 |
| » Lost to Browns (44-33), 5-4 | Griffith Stadium (22-19) | 37-38 | |
| » Starters: Sig Jakucki vs Johnny Niggeling | Fourth | 6 out |
| Sunday, July 9 |
| » Lost to Browns (45-33), 10-0 | Griffith Stadium (22-20) | 37-39 | Lost 2 |
| » Starters: Tex Shirley vs Early Wynn | Fourth | 6 out |
| » Defeated Browns (45-34), 4-0 | Griffith Stadium (23-20) | 38-39 | |
| » Starters: Al Hollingsworth vs Dutch Leonard | Fourth | 6 out |
| Friday, July 14 |
| » Lost to Athletics (36-42), 4-3 | Griffith Stadium (23-21) | 38-40 | |
| » Starters: Lum Harris vs Johnny Niggeling | Fourth | 6½ out |
| » Lost to Athletics (37-42), 4-3 | Griffith Stadium (23-22) | 38-41 | Lost 2 |
| » Starters: Russ Christopher vs Early Wynn | Fourth | 6½ out |
| Saturday, July 15 |
| » Defeated Athletics (37-43), 5-2 | Griffith Stadium (24-22) | 39-41 | |
| » Starters: Bobo Newsom vs Dutch Leonard | Fourth | 5½ out |
| Sunday, July 16 |
| » Defeated Athletics (37-44), 8-4 | Griffith Stadium (25-22) | 40-41 | Won 2 |
| » Starters: Luke Hamlin vs Milo Candini | Fourth | 5½ out |
| » Defeated Athletics (37-45), 4-3 | Griffith Stadium (26-22) | 41-41 | Won 3 |
| » Starters: Jesse Flores vs Mickey Haefner | Fourth | 5½ out |
| Tuesday, July 18 |
| » Lost to Tigers (41-44), 6-5 | Tiger Stadium (1-3) | 41-42 | |
| » Starters: Early Wynn vs Johnny Gorsica | Fourth | 6½ out |
| Wednesday, July 19 |
| » Lost to Tigers (42-44), 2-1 | Tiger Stadium (1-4) | 41-43 | Lost 2 |
| » Starters: Dutch Leonard vs Stubby Overmire | Fourth | 6½ out |
| Thursday, July 20 |
| » Lost to Tigers (43-44), 7-6 | Tiger Stadium (1-5) | 41-44 | Lost 3 |
| » Starters: Milo Candini vs Boom-Boom Beck | Fifth | 7½ out |
| Friday, July 21 |
| » Lost to Tigers (44-44), 6-5 | Tiger Stadium (1-6) | 41-45 | Lost 4 |
| » Starters: Johnny Niggeling vs Dizzy Trout | Fifth | 7½ out |
| Saturday, July 22 |
| » Defeated Indians (44-45), 9-6 | League Park II (3-1) | 42-45 | |
| » Starters: Mickey Haefner vs Allie Reynolds | Sixth | 6½ out |
| Sunday, July 23 |
| » Lost to Indians (45-45), 4-3 | Cleveland Stadium (1-1) | 42-46 | |
| » Starters: Dutch Leonard vs Al Smith | Seventh | 7½ out |
| » Lost to Indians (46-45), 9-5 | Cleveland Stadium (1-2) | 42-47 | Lost 2 |
| » Starters: Milo Candini vs Mel Harder | Seventh | 7½ out |
| Monday, July 24 |
| » Lost to Indians (47-45), 10-1 | League Park II (3-2) | 42-48 | Lost 3 |
| » Starters: Early Wynn vs Ed Klieman | Seventh | 8½ out |
| Tuesday, July 25 |
| » Lost to White Sox (42-45), 9-6 | Comiskey Park I (0-5) | 42-49 | Lost 4 |
| » Starters: Mickey Haefner vs Bill Dietrich | Seventh | 9½ out |
| Wednesday, July 26 |
| » Lost to White Sox (43-45), 4-3 | Comiskey Park I (0-6) | 42-50 | Lost 5 |
| » Starters: Johnny Niggeling vs Johnny Humphries | Seventh | 10½ out |
| Thursday, July 27 |
| » Lost to White Sox (44-45), 4-0 | Comiskey Park I (0-7) | 42-51 | Lost 6 |
| » Starters: Dutch Leonard vs Orval Grove | Seventh | 10½ out |
| Friday, July 28 |
| » Lost to White Sox (45-45), 8-2 | Comiskey Park I (0-8) | 42-52 | Lost 7 |
| » Starters: Bill LeFebvre vs Ed Lopat | Seventh | 11½ out |
| Sunday, July 30 |
| » Lost to Browns (56-42), 2-1 | Sportsman's Park III (1-4) | 42-53 | Lost 8 |
| » Starters: Mickey Haefner vs Bob Muncrief | Seventh | 13½ out |
| » Lost to Browns (57-42), 7-3 | Sportsman's Park III (1-5) | 42-54 | Lost 9 |
| » Starters: Early Wynn vs Denny Galehouse | Seventh | 13½ out |
| Monday, July 31 |
| » Lost to Browns (58-42), 3-2 | Sportsman's Park III (1-6) | 42-55 | Lost 10 |
| » Starters: Roger Wolff vs Jack Kramer | Eighth | 14½ out |
| Tuesday, August 1 |
| » Lost to Browns (59-42), 11-6 | Sportsman's Park III (1-7) | 42-56 | Lost 11 |
| » Starters: Dutch Leonard vs Sig Jakucki | Eighth | 15½ out |
| Friday, August 4 |
| » Defeated Red Sox (52-47), 7-5 | Fenway Park (5-2) | 43-56 | |
| » Starters: Johnny Niggeling vs Yank Terry | Eighth | 15½ out |
| » Lost to Red Sox (53-47), 4-0 | Fenway Park (5-3) | 43-57 | |
| » Starters: Early Wynn vs Emmett O'Neill | Eighth | 15½ out |
| Saturday, August 5 |
| » Lost to Red Sox (54-47), 6-2 | Fenway Park (5-4) | 43-58 | Lost 2 |
| » Starters: Roger Wolff vs Tex Hughson | Eighth | 16½ out |
| Sunday, August 6 |
| » Defeated Red Sox (54-48), 3-2 | Fenway Park (6-4) | 44-58 | |
| » Starters: Dutch Leonard vs Joe Bowman | Eighth | 17½ out |
| » Lost to Red Sox (55-48), 5-4 | Fenway Park (6-5) | 44-59 | |
| » Starters: Milo Candini vs Pinky Woods | Eighth | 17½ out |
| Wednesday, August 9 |
| » Lost to Tigers (53-50), 4-2 | Griffith Stadium (26-23) | 44-60 | Lost 2 |
| » Starters: Hal Newhouser vs Early Wynn | Eighth | 18½ out |
| Thursday, August 10 |
| » Lost to Tigers (54-50), 3-2 | Griffith Stadium (26-24) | 44-61 | Lost 3 |
| » Starters: Dizzy Trout vs Johnny Niggeling | Eighth | 19½ out |
| Friday, August 11 |
| » Lost to Tigers (55-50), 11-4 | Griffith Stadium (26-25) | 44-62 | Lost 4 |
| » Starters: Stubby Overmire vs Dutch Leonard | Eighth | 19½ out |
| Saturday, August 12 |
| » Lost to Tigers (56-50), 12-5 | Griffith Stadium (26-26) | 44-63 | Lost 5 |
| » Starters: Rufe Gentry vs Alex Carrasquel | Eighth | 20½ out |
| Sunday, August 13 |
| » Defeated Indians (53-58), 2-1 | Griffith Stadium (27-26) | 45-63 | |
| » Starters: Jim Bagby vs Mickey Haefner | Eighth | 19½ out |
| » Defeated Indians (53-59), 4-1 | Griffith Stadium (28-26) | 46-63 | Won 2 |
| » Starters: Ray Poat vs Early Wynn | Eighth | 19½ out |
| Monday, August 14 |
| » Defeated Indians (53-60), 8-5 | Griffith Stadium (29-26) | 47-63 | Won 3 |
| » Starters: Steve Gromek vs Roger Wolff | Eighth | 18½ out |
| Tuesday, August 15 |
| » Lost to Indians (54-60), 1-0 | Griffith Stadium (29-27) | 47-64 | |
| » Starters: Al Smith vs Dutch Leonard | Eighth | 19½ out |
| Wednesday, August 16 |
| » Lost to White Sox (53-59), 7-2 | Griffith Stadium (29-28) | 47-65 | Lost 2 |
| » Starters: Ed Lopat vs Johnny Niggeling | Eighth | 19½ out |
| » Major-league debuts: Eddie Yost (Senators) |
| Thursday, August 17 |
| » Lost to White Sox (54-59), 1-0 | Griffith Stadium (29-29) | 47-66 | Lost 3 |
| » Starters: Bill Dietrich vs Mickey Haefner | Seventh | 20½ out |
| Friday, August 18 |
| » Lost to White Sox (55-59), 2-1 | Griffith Stadium (29-30) | 47-67 | Lost 4 |
| » Starters: Johnny Humphries vs Roger Wolff | Eighth | 20½ out |
| Saturday, August 19 |
| » Defeated White Sox (55-60), 3-2 | Griffith Stadium (30-30) | 48-67 | |
| » Starters: Jake Wade vs Alex Carrasquel | Eighth | 19½ out |
| Sunday, August 20 |
| » Defeated Browns (68-49), 4-2 | Griffith Stadium (31-30) | 49-67 | Won 2 |
| » Starters: Denny Galehouse vs Dutch Leonard | Seventh | 17½ out |
| » Defeated Browns (68-50), 12-1 | Griffith Stadium (32-30) | 50-67 | Won 3 |
| » Starters: Jack Kramer vs Early Wynn | Seventh | 17½ out |
| Monday, August 21 |
| » Lost to Browns (69-50), 5-3 | Griffith Stadium (32-31) | 50-68 | |
| » Starters: Sig Jakucki vs Mickey Haefner | Seventh | 18½ out |
| Tuesday, August 22 |
| » Defeated Browns (69-51), 3-0 | Griffith Stadium (33-31) | 51-68 | |
| » Starters: Nels Potter vs Johnny Niggeling | Seventh | 17½ out |
| Friday, August 25 |
| » Lost to Yankees (63-55), 4-2 | Griffith Stadium (33-32) | 51-69 | |
| » Starters: Atley Donald vs Roger Wolff | Eighth | 17½ out |
| Future Senator Dick Smith is born in Lincolnton, NC. |
| Saturday, August 26 |
| » Lost to Yankees (64-55), 10-3 | Griffith Stadium (33-33) | 51-70 | Lost 2 |
| » Starters: Hank Borowy vs Dutch Leonard | Eighth | 17½ out |
| Sunday, August 27 |
| » Lost to Yankees (65-55), 4-2 | Griffith Stadium (33-34) | 51-71 | Lost 3 |
| » Starters: Monk Dubiel vs Mickey Haefner | Eighth | 17½ out |
| » Defeated Yankees (65-56), 5-4 | Griffith Stadium (34-34) | 52-71 | |
| » Starters: Mel Queen vs Alex Carrasquel | Eighth | 17½ out |
| Tuesday, August 29 |
| » Lost to Athletics (61-67), 3-1 | Shibe Park (5-4) | 52-72 | |
| » Starters: Johnny Niggeling vs Bobo Newsom | Eighth | 19 out |
| » Lost to Athletics (62-67), 11-4 | Shibe Park (5-5) | 52-73 | Lost 2 |
| » Starters: Roger Wolff vs Jesse Flores | Eighth | 19 out |
| Wednesday, August 30 |
| » Defeated Athletics (62-68), 9-4 | Shibe Park (6-5) | 53-73 | |
| » Starters: Dutch Leonard vs Luke Hamlin | Eighth | 18 out |
| Thursday, August 31 |
| » Lost to Yankees (68-58), 9-4 | Yankee Stadium (1-5) | 53-74 | |
| » Starters: Mickey Haefner vs Monk Dubiel | Eighth | 18½ out |
| » Lost to Yankees (69-58), 4-3 | Yankee Stadium (1-6) | 53-75 | Lost 2 |
| » Starters: Alex Carrasquel vs Mel Queen | Eighth | 18½ out |
| Friday, September 1 |
| » Defeated Yankees (69-59), 10-7 | Yankee Stadium (2-6) | 54-75 | |
| » Starters: Jug Thesenga vs Steve Roser | Eighth | 17½ out |
| Saturday, September 2 |
| » Lost to Yankees (70-59), 3-1 | Yankee Stadium (2-7) | 54-76 | |
| » Starters: Bill LeFebvre vs Tiny Bonham | Eighth | 17½ out |
| Sunday, September 3 |
| » Lost to Yankees (71-59), 6-5 | Yankee Stadium (2-8) | 54-77 | Lost 2 |
| » Starters: Dutch Leonard vs Bill Bevens | Eighth | 19 out |
| » Lost to Yankees (72-59), 11-3 | Yankee Stadium (2-9) | 54-78 | Lost 3 |
| » Starters: Roger Wolff vs Hank Borowy | Eighth | 19 out |
| Monday, September 4 |
| » Lost to Red Sox (71-61), 11-7 | Griffith Stadium (34-35) | 54-79 | Lost 4 |
| » Starters: Rex Cecil vs Johnny Niggeling | Eighth | 19½ out |
| » Defeated Red Sox (71-62), 9-2 | Griffith Stadium (35-35) | 55-79 | |
| » Starters: Emmett O'Neill vs Mickey Haefner | Eighth | 19½ out |
| Friday, September 8 |
| » Defeated Athletics (63-73), 4-0 | Griffith Stadium (36-35) | 56-79 | Won 2 |
| » Starters: Russ Christopher vs Mickey Haefner | Eighth | 19½ out |
| Saturday, September 9 |
| » Lost to Athletics (64-73), 3-1 | Griffith Stadium (36-36) | 56-80 | |
| » Starters: Bobo Newsom vs Roger Wolff | Eighth | 19½ out |
| Sunday, September 10 |
| » Defeated Athletics (64-74), 2-1 | Griffith Stadium (37-36) | 57-80 | |
| » Starters: Jesse Flores vs Dutch Leonard | Eighth | 18½ out |
| » Defeated Athletics (64-75), 8-2 | Griffith Stadium (38-36) | 58-80 | Won 2 |
| » Starters: Don Black vs Alex Carrasquel | Eighth | 18½ out |
| Friday, September 15 |
| » Defeated Red Sox (73-65), 5-2 | Griffith Stadium (39-36) | 59-80 | Won 3 |
| » Starters: Clem Dreisewerd vs Mickey Haefner | Seventh | 18 out |
| Saturday, September 16 |
| » Lost to Red Sox (74-65), 11-5 | Griffith Stadium (39-37) | 59-81 | |
| » Starters: Mike Ryba vs Roger Wolff | Seventh | 18½ out |
| Sunday, September 17 |
| » Defeated Red Sox (74-66), 7-6 | Griffith Stadium (40-37) | 60-81 | |
| » Starters: Joe Bowman vs Dutch Leonard | Eighth | 18½ out |
| Tuesday, September 19 |
| » Defeated Browns (78-64), 6-0 | Sportsman's Park III (2-7) | 61-81 | Won 2 |
| » Starters: Johnny Niggeling vs Denny Galehouse | Eighth | 18½ out |
| Wednesday, September 20 |
| » Lost to Browns (79-64), 5-2 | Sportsman's Park III (2-8) | 61-82 | |
| » Starters: Mickey Haefner vs Jack Kramer | Eighth | 19½ out |
| Thursday, September 21 |
| » Lost to Browns (80-64), 9-4 | Sportsman's Park III (2-9) | 61-83 | Lost 2 |
| » Starters: Dutch Leonard vs Nels Potter | Eighth | 19½ out |
| Saturday, September 23 |
| » Lost to White Sox (67-77), 5-4 | Comiskey Park I (0-9) | 61-84 | Lost 3 |
| » Starters: Baby Ortiz vs Bill Dietrich | Eighth | 21½ out |
| » Major-league debuts: George Binks and Baby Ortiz (Senators) |
| Sunday, September 24 |
| » Lost to White Sox (68-77), 9-3 | Comiskey Park I (0-10) | 61-85 | Lost 4 |
| » Starters: Roger Wolff vs Thornton Lee | Eighth | 23 out |
| » Lost to White Sox (69-77), 2-0 | Comiskey Park I (0-11) | 61-86 | Lost 5 |
| » Starters: Vern Curtis vs Ed Lopat | Eighth | 23 out |
| Monday, September 25 |
| » Lost to Indians (71-77), 6-0 | Cleveland Stadium (1-3) | 61-87 | Lost 6 |
| » Starters: Mickey Haefner vs Ed Klieman | Seventh | 23 out |
| Tuesday, September 26 |
| » Defeated Indians (71-78), 8-3 | League Park II (4-2) | 62-87 | |
| » Starters: Dutch Leonard vs Al Smith | Seventh | 23 out |
| Wednesday, September 27 |
| » Lost to Indians (72-78), 6-4 | League Park II (4-3) | 62-88 | |
| » Starters: Baby Ortiz vs Earl Henry | Eighth | 24 out |
| Friday, September 29 |
| » Lost to Tigers (87-64), 5-2 | Tiger Stadium (1-7) | 62-89 | Lost 2 |
| » Starters: Johnny Niggeling vs Rufe Gentry | Seventh | 24 out |
| » Defeated Tigers (87-65), 9-2 | Tiger Stadium (2-7) | 63-89 | |
| » Starters: Mickey Haefner vs Dizzy Trout | Seventh | 24 out |
| Saturday, September 30 |
| » Lost to Tigers (88-65), 7-3 | Tiger Stadium (2-8) | 63-90 | |
| » Starters: Alex Carrasquel vs Hal Newhouser | Sixth | 25 out |
| Sunday, October 1 |
| » Defeated Tigers (88-66), 4-1 | Tiger Stadium (3-8) | 64-90 | |
| » Starters: Dutch Leonard vs Dizzy Trout | Seventh | 25 out |
| Sunday, October 15 |
| Future Senator Dick Such is born in Sanford, NC. |
| Monday, December 4 |
| Former Senator Roger Bresnahan dies in Toledo, OH at the age of 66. |
| Saturday, December 9 |
| Future Senator Del Unser is born in Decatur, IL. |
Game information provided by Retrosheet (www.retrosheet.org) |