| Monday, January 17 |
| Future Red Sox Denny Doyle is born in Glasgow, KY. |
| Friday, March 17 |
| Former Red Sox Rube Kroh dies in New Orleans, LA at the age of 58. |
| Thursday, March 23 |
| Future Red Sox George Scott is born in Greenville, MS. |
| Sunday, April 16 |
| Future Red Sox Bob Montgomery is born in Nashville, TN. |
| Tuesday, April 18 |
| » Lost to Yankees (1-0), 3-0 | Fenway Park (0-1) | 0-1 | |
| » Starters: Hank Borowy vs Yank Terry | Third | 1 out |
| Wednesday, April 19 |
| » Defeated Yankees (1-1), 6-1 | Fenway Park (1-1) | 1-1 | |
| » Starters: Johnny Johnson vs Pinky Woods | Third | ½ out |
| » Defeated Yankees (1-2), 5-2 | Fenway Park (2-1) | 2-1 | Won 2 |
| » Starters: Monk Dubiel vs Emmett O'Neill | Third | ½ out |
| » Major-league debuts: Bill Drescher and Monk Dubiel (Yankees) |
| Saturday, April 22 |
| » Lost to Athletics (2-1), 4-0 | Shibe Park (0-1) | 2-2 | |
| » Starters: Joe Bowman vs Bobo Newsom | Fourth | 2 out |
| Tuesday, April 25 |
| » Defeated Senators (1-3), 5-4 | Griffith Stadium (1-0) | 3-2 | |
| » Starters: Emmett O'Neill vs Johnny Niggeling | Third | 2½ out |
| Future Red Sox Ken Tatum is born in Alexandria, LA. |
| Wednesday, April 26 |
| » Lost to Senators (2-3), 2-1 | Griffith Stadium (1-1) | 3-3 | |
| » Starters: Yank Terry vs Early Wynn | Third | 3½ out |
| Friday, April 28 |
| » Lost to Athletics (4-2), 7-5 | Fenway Park (2-2) | 3-4 | Lost 2 |
| » Starters: Bobo Newsom vs Pinky Woods | Fourth | 5 out |
| » Major-league debuts: Clem Hausmann (Red Sox) |
| Saturday, April 29 |
| » Defeated Athletics (4-3), 7-0 | Fenway Park (3-2) | 4-4 | |
| » Starters: Russ Christopher vs Joe Bowman | Fourth | 4 out |
| Sunday, April 30 |
| » Defeated Athletics (4-4), 3-2 | Fenway Park (4-2) | 5-4 | Won 2 |
| » Starters: Don Black vs Tex Hughson | Third | 4 out |
| » Lost to Athletics (5-4), 3-1 | Fenway Park (4-3) | 5-5 | |
| » Starters: Lum Harris vs Emmett O'Neill | Third | 4 out |
| Monday, May 1 |
| » Lost to Senators (4-5), 11-4 | Fenway Park (4-4) | 5-6 | Lost 2 |
| » Starters: Roger Wolff vs Yank Terry | Third | 4½ out |
| » Major-league debuts: Joe Wood (Red Sox) |
| Tuesday, May 2 |
| » Lost to Senators (5-5), 5-2 | Fenway Park (4-5) | 5-7 | Lost 3 |
| » Starters: Johnny Niggeling vs Pinky Woods | Fourth | 4½ out |
| Wednesday, May 3 |
| » Defeated Senators (5-6), 11-10 | Fenway Park (5-5) | 6-7 | |
| » Starters: Dutch Leonard vs Vic Johnson | Third | 4½ out |
| » Major-league debuts: Sandy Ullrich (Senators) |
| Friday, May 5 |
| » Lost to Yankees (8-4), 11-7 | Yankee Stadium (0-1) | 6-8 | |
| » Starters: Tex Hughson vs Atley Donald | Fourth | 5½ out |
| Saturday, May 6 |
| » Lost to Yankees (9-4), 4-3 | Yankee Stadium (0-2) | 6-9 | Lost 2 |
| » Starters: Emmett O'Neill vs Joe Page | Sixth | 5½ out |
| Wednesday, May 10 |
| » Lost to Indians (9-9), 5-4 | Fenway Park (5-6) | 6-10 | Lost 3 |
| » Starters: Mel Harder vs Pinky Woods | Seventh | 5½ out |
| Thursday, May 11 |
| » Lost to Indians (10-9), 7-6 | Fenway Park (5-7) | 6-11 | Lost 4 |
| » Starters: Allie Reynolds vs Joe Bowman | Seventh | 5 out |
| Friday, May 12 |
| » Defeated Indians (10-10), 10-3 | Fenway Park (6-7) | 7-11 | |
| » Starters: Vern Kennedy vs Tex Hughson | Seventh | 5½ out |
| Saturday, May 13 |
| » Defeated Tigers (7-14), 4-2 | Fenway Park (7-7) | 8-11 | Won 2 |
| » Starters: Rufe Gentry vs Emmett O'Neill | Seventh | 4 out |
| Sunday, May 14 |
| » Lost to Tigers (8-14), 6-1 | Fenway Park (7-8) | 8-12 | |
| » Starters: Dizzy Trout vs Joe Wood | Eighth | 6 out |
| » Lost to Tigers (9-14), 9-0 | Fenway Park (7-9) | 8-13 | Lost 2 |
| » Starters: Johnny Gorsica vs Yank Terry | Eighth | 6 out |
| Tuesday, May 16 |
| » Lost to Browns (15-10), 7-3 | Fenway Park (7-10) | 8-14 | Lost 3 |
| » Starters: Jack Kramer vs Vic Johnson | Seventh | 6½ out |
| Wednesday, May 17 |
| » Defeated Browns (15-11), 5-1 | Fenway Park (8-10) | 9-14 | |
| » Starters: Bob Muncrief vs Tex Hughson | Eighth | 6 out |
| » Lost to Browns (16-11), 12-8 | Fenway Park (8-11) | 9-15 | |
| » Starters: Sig Jakucki vs Emmett O'Neill | Eighth | 6 out |
| Thursday, May 18 |
| » Defeated Browns (16-12), 12-1 | Fenway Park (9-11) | 10-15 | |
| » Starters: Tex Shirley vs Oscar Judd | Seventh | 5 out |
| Friday, May 19 |
| » Defeated White Sox (13-14), 3-2 | Fenway Park (10-11) | 11-15 | Won 2 |
| » Starters: Ed Lopat vs Clem Hausmann | Seventh | 4½ out |
| Saturday, May 20 |
| » Defeated White Sox (13-15), 8-1 | Fenway Park (11-11) | 12-15 | Won 3 |
| » Starters: Thornton Lee vs Joe Bowman | Seventh | 4 out |
| Sunday, May 21 |
| » Defeated White Sox (13-16), 4-3 | Fenway Park (12-11) | 13-15 | Won 4 |
| » Starters: Bill Dietrich vs Tex Hughson | Fifth | 4 out |
| » Defeated White Sox (13-17), 9-2 | Fenway Park (13-11) | 14-15 | Won 5 |
| » Starters: Orval Grove vs Emmett O'Neill | Fifth | 4 out |
| Wednesday, May 24 |
| » Lost to Browns (18-15), 7-3 | Sportsman's Park III (0-1) | 14-16 | |
| » Starters: Vic Johnson vs Jack Kramer | Sixth | 4½ out |
| Thursday, May 25 |
| » Lost to Browns (19-15), 3-2 | Sportsman's Park III (0-2) | 14-17 | Lost 2 |
| » Starters: Tex Hughson vs Bob Muncrief | Sixth | 5 out |
| Friday, May 26 |
| » Defeated Browns (19-16), 4-2 | Sportsman's Park III (1-2) | 15-17 | |
| » Starters: Oscar Judd vs Nels Potter | Fifth | 5 out |
| Saturday, May 27 |
| » Lost to Browns (20-16), 4-2 | Sportsman's Park III (1-3) | 15-18 | |
| » Starters: Stan Partenheimer vs Sig Jakucki | Sixth | 5 out |
| Sunday, May 28 |
| » Defeated White Sox (14-19), 6-4 | Comiskey Park I (1-0) | 16-18 | |
| » Starters: Joe Bowman vs Ed Lopat | Fifth | 5 out |
| » Defeated White Sox (14-20), 4-2 | Comiskey Park I (2-0) | 17-18 | Won 2 |
| » Starters: Clem Hausmann vs Thornton Lee | Fifth | 5 out |
| Monday, May 29 |
| » Defeated White Sox (14-21), 3-1 | Comiskey Park I (3-0) | 18-18 | Won 3 |
| » Starters: Tex Hughson vs Buck Ross | Fourth | 4 out |
| Tuesday, May 30 |
| » Lost to Indians (17-22), 9-3 | Cleveland Stadium (0-1) | 18-19 | |
| » Starters: Emmett O'Neill vs Mel Harder | Fifth | 4 out |
| » Lost to Indians (18-22), 4-3 | Cleveland Stadium (0-2) | 18-20 | Lost 2 |
| » Starters: Yank Terry vs Allie Reynolds | Fifth | 4 out |
| Wednesday, May 31 |
| » Lost to Indians (19-22), 7-4 | League Park II (0-1) | 18-21 | Lost 3 |
| » Starters: Oscar Judd vs Vern Kennedy | Seventh | 4½ out |
| Thursday, June 1 |
| » Defeated Indians (19-23), 7-6 | League Park II (1-1) | 19-21 | |
| » Starters: Vic Johnson vs Hal Kleine | Sixth | 3½ out |
| Friday, June 2 |
| » Lost to Tigers (23-20), 4-1 | Tiger Stadium (0-1) | 19-22 | |
| » Starters: Joe Bowman vs Johnny Gorsica | Sixth | 4½ out |
| Saturday, June 3 |
| » Defeated Tigers (23-21), 11-1 | Tiger Stadium (1-1) | 20-22 | |
| » Starters: Tex Hughson vs Joe Orrell | Fourth | 4½ out |
| Sunday, June 4 |
| » Lost to Tigers (24-21), 2-1 | Tiger Stadium (1-2) | 20-23 | |
| » Starters: Pinky Woods vs Dizzy Trout | Fifth | 4½ out |
| » Defeated Tigers (24-22), 5-1 | Tiger Stadium (2-2) | 21-23 | |
| » Starters: Clem Hausmann vs Rufe Gentry | Fifth | 4½ out |
| Wednesday, June 7 |
| » Defeated Yankees (22-19), 8-1 | Fenway Park (14-11) | 22-23 | Won 2 |
| » Starters: Hank Borowy vs Tex Hughson | Fifth | 4 out |
| Thursday, June 8 |
| » Defeated Yankees (22-20), 8-7 | Fenway Park (15-11) | 23-23 | Won 3 |
| » Starters: Joe Page vs Pinky Woods | Fifth | 3 out |
| Sunday, June 11 |
| » Defeated Yankees (22-21), 2-1 | Fenway Park (16-11) | 24-23 | Won 4 |
| » Starters: Hank Borowy vs Tex Hughson | Second | 1½ out |
| » Defeated Yankees (22-22), 4-1 | Fenway Park (17-11) | 25-23 | Won 5 |
| » Starters: Monk Dubiel vs Clem Hausmann | Second | 1½ out |
| Tuesday, June 13 |
| » Defeated Athletics (22-25), 7-2 | Fenway Park (18-11) | 26-23 | Won 6 |
| » Starters: Jesse Flores vs Joe Bowman | Second | 1½ out |
| Wednesday, June 14 |
| » Defeated Athletics (22-26), 6-4 | Fenway Park (19-11) | 27-23 | Won 7 |
| » Starters: Luke Hamlin vs Emmett O'Neill | Second | 1 out |
| » Defeated Athletics (22-27), 5-0 | Fenway Park (20-11) | 28-23 | Won 8 |
| » Starters: Russ Christopher vs Pinky Woods | Second | 1 out |
| Thursday, June 15 |
| » Defeated Athletics (22-28), 5-1 | Fenway Park (21-11) | 29-23 | Won 9 |
| » Starters: Lum Harris vs Tex Hughson | Second | ½ out |
| Friday, June 16 |
| » Lost to Senators (26-27), 4-0 | Griffith Stadium (1-2) | 29-24 | |
| » Starters: Clem Hausmann vs Milo Candini | Second | 1½ out |
| Saturday, June 17 |
| » Defeated Senators (26-28), 11-4 | Griffith Stadium (2-2) | 30-24 | |
| » Starters: Joe Bowman vs Roger Wolff | Second | 1½ out |
| » Major-league debuts: Gene Patton (Red Sox) |
| Sunday, June 18 |
| » Defeated Senators (26-29), 9-6 | Griffith Stadium (3-2) | 31-24 | Won 2 |
| » Starters: Oscar Judd vs Dutch Leonard | Second | ½ out |
| » Lost to Senators (27-29), 1-0 | Griffith Stadium (3-3) | 31-25 | |
| » Starters: Pinky Woods vs Early Wynn | Second | ½ out |
| Tuesday, June 20 |
| » Lost to Athletics (26-30), 5-4 | Shibe Park (0-2) | 31-26 | Lost 2 |
| » Starters: Tex Hughson vs Lum Harris | Second | 1½ out |
| » Lost to Athletics (27-30), 2-0 | Shibe Park (0-3) | 31-27 | Lost 3 |
| » Starters: Yank Terry vs Bobo Newsom | Second | 1½ out |
| Wednesday, June 21 |
| » Lost to Athletics (28-30), 5-2 | Shibe Park (0-4) | 31-28 | Lost 4 |
| » Starters: Clem Hausmann vs Jesse Flores | Second | 2½ out |
| Thursday, June 22 |
| » Defeated Athletics (28-31), 5-4 | Shibe Park (1-4) | 32-28 | |
| » Starters: Joe Bowman vs Don Black | Second | 2 out |
| » Lost to Athletics (29-31), 3-2 | Shibe Park (1-5) | 32-29 | |
| » Starters: Pinky Woods vs Russ Christopher | Second | 2 out |
| Friday, June 23 |
| » Lost to Senators (29-32), 7-1 | Fenway Park (21-12) | 32-30 | Lost 2 |
| » Starters: Early Wynn vs Vic Johnson | Second | 3 out |
| Sunday, June 25 |
| » Lost to Senators (30-32), 5-4 | Fenway Park (21-13) | 32-31 | Lost 3 |
| » Starters: Roger Wolff vs Clem Hausmann | Fourth | 4½ out |
| » Defeated Senators (30-33), 4-0 | Fenway Park (22-13) | 33-31 | |
| » Starters: Milo Candini vs Tex Hughson | Fourth | 4½ out |
| Wednesday, June 28 |
| » Defeated White Sox (30-28), 4-3 | Fenway Park (23-13) | 34-31 | Won 2 |
| » Starters: Orval Grove vs Joe Bowman | Third | 3½ out |
| Thursday, June 29 |
| » Defeated White Sox (30-29), 5-4 | Fenway Park (24-13) | 35-31 | Won 3 |
| » Starters: Ed Lopat vs Tex Hughson | Third | 2½ out |
| Friday, June 30 |
| » Defeated White Sox (30-30), 11-0 | Fenway Park (25-13) | 36-31 | Won 4 |
| » Starters: Bill Dietrich vs Oscar Judd | Second | 2½ out |
| Saturday, July 1 |
| » Lost to Browns (40-29), 9-1 | Fenway Park (25-14) | 36-32 | |
| » Starters: Nels Potter vs Clem Hausmann | Second | 3½ out |
| Sunday, July 2 |
| » Defeated Browns (40-30), 1-0 | Fenway Park (26-14) | 37-32 | |
| » Starters: Jack Kramer vs Tex Hughson | Second | 1½ out |
| » Defeated Browns (40-31), 4-3 | Fenway Park (27-14) | 38-32 | Won 2 |
| » Starters: Tex Shirley vs Pinky Woods | Second | 1½ out |
| Tuesday, July 4 |
| » Lost to Tigers (34-37), 4-3 | Fenway Park (27-15) | 38-33 | |
| » Starters: Hal Newhouser vs Clem Hausmann | Second | 1½ out |
| » Defeated Tigers (34-38), 7-4 | Fenway Park (28-15) | 39-33 | |
| » Starters: Johnny Gorsica vs Joe Bowman | Second | 1½ out |
| Wednesday, July 5 |
| » Lost to Tigers (35-38), 8-1 | Fenway Park (28-16) | 39-34 | |
| » Starters: Dizzy Trout vs Emmett O'Neill | Second | 2½ out |
| Thursday, July 6 |
| » Defeated Tigers (35-39), 13-3 | Fenway Park (29-16) | 40-34 | |
| » Starters: Rufe Gentry vs Tex Hughson | Second | 2½ out |
| Friday, July 7 |
| » Lost to Indians (36-39), 8-5 | Fenway Park (29-17) | 40-35 | |
| » Starters: Steve Gromek vs Pinky Woods | Second | 2½ out |
| Saturday, July 8 |
| » Defeated Indians (36-40), 11-7 | Fenway Park (30-17) | 41-35 | |
| » Starters: Allie Reynolds vs Yank Terry | Second | 2½ out |
| Sunday, July 9 |
| » Lost to Indians (37-40), 8-2 | Fenway Park (30-18) | 41-36 | |
| » Starters: Ed Klieman vs Clem Hausmann | Second | 2½ out |
| » Defeated Indians (37-41), 4-2 | Fenway Park (31-18) | 42-36 | |
| » Starters: Ray Poat vs Joe Bowman | Second | 2½ out |
| Thursday, July 13 |
| » Lost to Yankees (40-35), 4-2 | Yankee Stadium (0-3) | 42-37 | |
| » Starters: Frank Barrett vs Tiny Bonham | Second | 2½ out |
| » Defeated Yankees (40-36), 8-4 | Yankee Stadium (1-3) | 43-37 | |
| » Starters: Yank Terry vs Atley Donald | Second | 2½ out |
| Friday, July 14 |
| » Lost to Yankees (41-36), 4-3 | Yankee Stadium (1-4) | 43-38 | |
| » Starters: Tex Hughson vs Hank Borowy | Third | 2½ out |
| Saturday, July 15 |
| » Lost to Yankees (42-36), 9-7 | Yankee Stadium (1-5) | 43-39 | Lost 2 |
| » Starters: Joe Bowman vs Monk Dubiel | Third | 2½ out |
| Sunday, July 16 |
| » Lost to Yankees (43-36), 7-1 | Yankee Stadium (1-6) | 43-40 | Lost 3 |
| » Starters: Clem Hausmann vs Atley Donald | Third | 4 out |
| Tuesday, July 18 |
| » Defeated White Sox (36-42), 4-2 | Comiskey Park I (4-0) | 44-40 | |
| » Starters: Tex Hughson vs Bill Dietrich | Third | 4 out |
| Wednesday, July 19 |
| » Lost to White Sox (37-42), 5-4 | Comiskey Park I (4-1) | 44-41 | |
| » Starters: Joe Bowman vs Orval Grove | Third | 4 out |
| Thursday, July 20 |
| » Defeated White Sox (37-43), 11-7 | Comiskey Park I (5-1) | 45-41 | |
| » Starters: Frank Barrett vs Jake Wade | Third | 4 out |
| Friday, July 21 |
| » Lost to White Sox (38-43), 5-3 | Comiskey Park I (5-2) | 45-42 | |
| » Starters: Yank Terry vs Buck Ross | Third | 4 out |
| Saturday, July 22 |
| » Defeated Browns (50-40), 8-4 | Sportsman's Park III (2-3) | 46-42 | |
| » Starters: Mike Ryba vs Jack Kramer | Third | 3 out |
| Future Red Sox Sparky Lyle is born in DuBois, PA. |
| Sunday, July 23 |
| » Defeated Browns (50-41), 12-1 | Sportsman's Park III (3-3) | 47-42 | Won 2 |
| » Starters: Tex Hughson vs Bob Muncrief | Third | 3 out |
| » Lost to Browns (51-41), 9-3 | Sportsman's Park III (3-4) | 47-43 | |
| » Starters: Joe Bowman vs Sig Jakucki | Third | 3 out |
| Monday, July 24 |
| » Lost to Browns (52-41), 6-5 | Sportsman's Park III (3-5) | 47-44 | Lost 2 |
| » Starters: Emmett O'Neill vs Denny Galehouse | Third | 4 out |
| Tuesday, July 25 |
| » Defeated Tigers (46-47), 7-3 | Tiger Stadium (3-2) | 48-44 | |
| » Starters: Yank Terry vs Rufe Gentry | Third | 4 out |
| Wednesday, July 26 |
| » Tied Tigers, 1-1 | Tiger Stadium (3-2) | 48-44 | |
| » Starters: Pinky Woods vs Hal Newhouser | Third | 4½ out |
| Thursday, July 27 |
| » Defeated Tigers (46-48), 6-1 | Tiger Stadium (4-2) | 49-44 | Won 2 |
| » Starters: Tex Hughson vs Stubby Overmire | Second | 3½ out |
| Friday, July 28 |
| » Defeated Tigers (46-49), 15-5 | Tiger Stadium (5-2) | 50-44 | Won 3 |
| » Starters: Emmett O'Neill vs Dizzy Trout | Third | 3½ out |
| Sunday, July 30 |
| » Defeated Indians (49-48), 5-3 | Cleveland Stadium (1-2) | 51-44 | Won 4 |
| » Starters: Yank Terry vs Ed Klieman | Second | 4½ out |
| » Lost to Indians (50-48), 3-2 | Cleveland Stadium (1-3) | 51-45 | |
| » Starters: Pinky Woods vs Mel Harder | Second | 4½ out |
| Monday, July 31 |
| » Defeated Indians (50-49), 1-0 | Cleveland Stadium (2-3) | 52-45 | |
| » Starters: Mike Ryba vs Steve Gromek | Second | 4½ out |
| Tuesday, August 1 |
| » Lost to Indians (51-49), 8-4 | League Park II (1-2) | 52-46 | |
| » Starters: Tex Hughson vs Jim Bagby | Second | 5½ out |
| Friday, August 4 |
| » Lost to Senators (43-56), 7-5 | Fenway Park (31-19) | 52-47 | Lost 2 |
| » Starters: Johnny Niggeling vs Yank Terry | Second | 5½ out |
| » Defeated Senators (43-57), 4-0 | Fenway Park (32-19) | 53-47 | |
| » Starters: Early Wynn vs Emmett O'Neill | Second | 5½ out |
| Saturday, August 5 |
| » Defeated Senators (43-58), 6-2 | Fenway Park (33-19) | 54-47 | Won 2 |
| » Starters: Roger Wolff vs Tex Hughson | Second | 5½ out |
| Sunday, August 6 |
| » Lost to Senators (44-58), 3-2 | Fenway Park (33-20) | 54-48 | |
| » Starters: Dutch Leonard vs Joe Bowman | Second | 6½ out |
| » Defeated Senators (44-59), 5-4 | Fenway Park (34-20) | 55-48 | |
| » Starters: Milo Candini vs Pinky Woods | Second | 6½ out |
| Wednesday, August 9 |
| » Defeated White Sox (50-54), 9-1 | Fenway Park (35-20) | 56-48 | Won 2 |
| » Starters: Bill Dietrich vs Tex Hughson | Second | 6½ out |
| Thursday, August 10 |
| » Defeated White Sox (50-55), 2-1 | Fenway Park (36-20) | 57-48 | Won 3 |
| » Starters: Joe Haynes vs Emmett O'Neill | Second | 6½ out |
| Friday, August 11 |
| » Lost to White Sox (51-55), 9-7 | Fenway Park (36-21) | 57-49 | |
| » Starters: Johnny Humphries vs Yank Terry | Second | 6½ out |
| Saturday, August 12 |
| » Defeated White Sox (51-56), 5-4 | Fenway Park (37-21) | 58-49 | |
| » Starters: Ed Lopat vs Joe Bowman | Second | 6½ out |
| Sunday, August 13 |
| » Defeated Browns (65-44), 7-6 | Fenway Park (38-21) | 59-49 | Won 2 |
| » Starters: Bob Muncrief vs Mike Ryba | Second | 6½ out |
| » Lost to Browns (66-44), 6-1 | Fenway Park (38-22) | 59-50 | |
| » Starters: Nels Potter vs Pinky Woods | Second | 6½ out |
| Monday, August 14 |
| » Defeated Browns (66-45), 5-1 | Fenway Park (39-22) | 60-50 | |
| » Starters: Denny Galehouse vs Emmett O'Neill | Second | 5½ out |
| Tuesday, August 15 |
| » Lost to Browns (67-45), 6-5 | Fenway Park (39-23) | 60-51 | |
| » Starters: Sig Jakucki vs Yank Terry | Second | 6½ out |
| Wednesday, August 16 |
| » Lost to Tigers (59-52), 4-2 | Fenway Park (39-24) | 60-52 | Lost 2 |
| » Starters: Rufe Gentry vs Rex Cecil | Second | 6½ out |
| Thursday, August 17 |
| » Tied Tigers, 3-3 | Fenway Park (39-24) | 60-52 | |
| » Starters: Dizzy Trout vs Pinky Woods | Second | 7 out |
| Friday, August 18 |
| » Lost to Tigers (60-52), 3-0 | Fenway Park (39-25) | 60-53 | Lost 3 |
| » Starters: Hal Newhouser vs Emmett O'Neill | Second | 6½ out |
| » Defeated Tigers (60-53), 7-4 | Fenway Park (40-25) | 61-53 | |
| » Starters: Johnny Gorsica vs Clem Hausmann | Second | 6½ out |
| Saturday, August 19 |
| » Defeated Tigers (60-54), 9-1 | Fenway Park (41-25) | 62-53 | Won 2 |
| » Starters: Rufe Gentry vs Joe Bowman | Second | 5½ out |
| Sunday, August 20 |
| » Defeated Indians (55-64), 8-6 | Fenway Park (42-25) | 63-53 | Won 3 |
| » Starters: Al Smith vs Yank Terry | Second | 3½ out |
| » Defeated Indians (55-65), 11-4 | Fenway Park (43-25) | 64-53 | Won 4 |
| » Starters: Ed Klieman vs Rex Cecil | Second | 3½ out |
| Monday, August 21 |
| » Lost to Indians (56-65), 7-6 | Fenway Park (43-26) | 64-54 | |
| » Starters: Jim Bagby vs Oscar Judd | Second | 4½ out |
| Tuesday, August 22 |
| » Lost to Indians (57-65), 5-3 | Fenway Park (43-27) | 64-55 | Lost 2 |
| » Starters: Steve Gromek vs Emmett O'Neill | Second | 4½ out |
| Friday, August 25 |
| » Lost to Athletics (58-65), 6-1 | Shibe Park (1-6) | 64-56 | Lost 3 |
| » Starters: Rex Cecil vs Bobo Newsom | Third | 5 out |
| » Lost to Athletics (59-65), 9-4 | Shibe Park (1-7) | 64-57 | Lost 4 |
| » Starters: Mike Ryba vs Jesse Flores | Third | 5 out |
| Saturday, August 26 |
| » Lost to Athletics (60-65), 6-1 | Shibe Park (1-8) | 64-58 | Lost 5 |
| » Starters: Emmett O'Neill vs Luke Hamlin | Fourth | 5 out |
| Sunday, August 27 |
| » Defeated Athletics (60-66), 8-5 | Shibe Park (2-8) | 65-58 | |
| » Starters: Joe Bowman vs Don Black | Fourth | 4 out |
| » Defeated Athletics (60-67), 7-2 | Shibe Park (3-8) | 66-58 | Won 2 |
| » Starters: Pinky Woods vs Russ Christopher | Fourth | 4 out |
| Monday, August 28 |
| » Defeated Yankees (65-57), 7-4 | Yankee Stadium (2-6) | 67-58 | Won 3 |
| » Starters: Yank Terry vs Bill Zuber | Second | 3½ out |
| Tuesday, August 29 |
| » Defeated Yankees (65-58), 8-1 | Yankee Stadium (3-6) | 68-58 | Won 4 |
| » Starters: Clem Dreisewerd vs Atley Donald | Third | 4 out |
| » Lost to Yankees (66-58), 11-2 | Yankee Stadium (3-7) | 68-59 | |
| » Starters: Rex Cecil vs Bill Bevens | Third | 4 out |
| » Major-league debuts: Clem Dreisewerd (Red Sox) |
| Wednesday, August 30 |
| » Lost to Yankees (67-58), 9-7 | Yankee Stadium (3-8) | 68-60 | Lost 2 |
| » Starters: Emmett O'Neill vs Hank Borowy | Fourth | 4 out |
| Friday, September 1 |
| » Defeated Athletics (62-69), 4-3 | Fenway Park (44-27) | 69-60 | |
| » Starters: Don Black vs Joe Bowman | Fourth | 2½ out |
| Saturday, September 2 |
| » Defeated Athletics (62-70), 6-5 | Fenway Park (45-27) | 70-60 | Won 2 |
| » Starters: Russ Christopher vs Pinky Woods | Fourth | 1½ out |
| Sunday, September 3 |
| » Lost to Athletics (63-70), 5-1 | Fenway Park (45-28) | 70-61 | |
| » Starters: Jesse Flores vs Clem Dreisewerd | Fourth | 2½ out |
| Monday, September 4 |
| » Defeated Senators (54-79), 11-7 | Griffith Stadium (4-3) | 71-61 | |
| » Starters: Rex Cecil vs Johnny Niggeling | Fourth | 3 out |
| » Lost to Senators (55-79), 9-2 | Griffith Stadium (4-4) | 71-62 | |
| » Starters: Emmett O'Neill vs Mickey Haefner | Fourth | 3 out |
| Friday, September 8 |
| » Lost to Yankees (75-59), 7-6 | Fenway Park (45-29) | 71-63 | Lost 2 |
| » Starters: Hank Borowy vs Joe Bowman | Fourth | 4 out |
| Saturday, September 9 |
| » Defeated Yankees (75-60), 7-1 | Fenway Park (46-29) | 72-63 | |
| » Starters: Tiny Bonham vs Rex Cecil | Fourth | 3 out |
| Sunday, September 10 |
| » Defeated Yankees (75-61), 3-2 | Fenway Park (47-29) | 73-63 | Won 2 |
| » Starters: Monk Dubiel vs Clem Dreisewerd | Fourth | 3 out |
| » Lost to Yankees (76-61), 4-3 | Fenway Park (47-30) | 73-64 | |
| » Starters: Mel Queen vs Emmett O'Neill | Fourth | 3 out |
| Friday, September 15 |
| » Lost to Senators (59-80), 5-2 | Griffith Stadium (4-5) | 73-65 | Lost 2 |
| » Starters: Clem Dreisewerd vs Mickey Haefner | Third | 3½ out |
| Saturday, September 16 |
| » Defeated Senators (59-81), 11-5 | Griffith Stadium (5-5) | 74-65 | |
| » Starters: Mike Ryba vs Roger Wolff | Third | 3 out |
| Sunday, September 17 |
| » Lost to Senators (60-81), 7-6 | Griffith Stadium (5-6) | 74-66 | |
| » Starters: Joe Bowman vs Dutch Leonard | Fourth | 4 out |
| Tuesday, September 19 |
| » Lost to Indians (67-75), 8-2 | Cleveland Stadium (2-4) | 74-67 | Lost 2 |
| » Starters: Rex Cecil vs Steve Gromek | Fourth | 5 out |
| Wednesday, September 20 |
| » Lost to Indians (68-75), 11-10 | League Park II (1-3) | 74-68 | Lost 3 |
| » Starters: Clem Dreisewerd vs Mel Harder | Fourth | 6 out |
| Thursday, September 21 |
| » Lost to Indians (69-75), 5-2 | League Park II (1-4) | 74-69 | Lost 4 |
| » Starters: Mike Ryba vs Ed Klieman | Fourth | 6 out |
| Friday, September 22 |
| » Lost to Tigers (81-63), 7-4 | Tiger Stadium (5-3) | 74-70 | Lost 5 |
| » Starters: Joe Bowman vs Rufe Gentry | Fourth | 8 out |
| » Lost to Tigers (82-63), 8-6 | Tiger Stadium (5-4) | 74-71 | Lost 6 |
| » Starters: Emmett O'Neill vs Johnny Gorsica | Fourth | 8 out |
| Saturday, September 23 |
| » Lost to Tigers (83-63), 8-2 | Tiger Stadium (5-5) | 74-72 | Lost 7 |
| » Starters: Rex Cecil vs Dizzy Trout | Fourth | 9 out |
| Sunday, September 24 |
| » Lost to Tigers (84-63), 9-5 | Tiger Stadium (5-6) | 74-73 | Lost 8 |
| » Starters: Yank Terry vs Hal Newhouser | Fourth | 10 out |
| Monday, September 25 |
| » Lost to Browns (84-64), 3-0 | Sportsman's Park III (3-6) | 74-74 | Lost 9 |
| » Starters: Clem Dreisewerd vs Nels Potter | Third | 10 out |
| Tuesday, September 26 |
| » Lost to Browns (85-64), 1-0 | Sportsman's Park III (3-7) | 74-75 | Lost 10 |
| » Starters: Mike Ryba vs Sig Jakucki | Third | 11 out |
| Wednesday, September 27 |
| » Defeated Browns (85-65), 4-1 | Sportsman's Park III (4-7) | 75-75 | |
| » Starters: Pinky Woods vs Denny Galehouse | Fourth | 11 out |
| Friday, September 29 |
| » Lost to White Sox (70-81), 4-3 | Comiskey Park I (5-3) | 75-76 | |
| » Starters: Clem Dreisewerd vs Thornton Lee | Third | 11½ out |
| Saturday, September 30 |
| » Defeated White Sox (70-82), 11-2 | Comiskey Park I (6-3) | 76-76 | |
| » Starters: Joe Bowman vs Orval Grove | Third | 11½ out |
| Sunday, October 1 |
| » Defeated White Sox (70-83), 3-1 | Comiskey Park I (7-3) | 77-76 | Won 2 |
| » Starters: Rex Cecil vs Joe Haynes | Fourth | 12 out |
| » Lost to White Sox (71-83), 4-1 | Comiskey Park I (7-4) | 77-77 | |
| » Starters: Pinky Woods vs Johnny Humphries | Fourth | 12 out |
| Wednesday, October 11 |
| Future Red Sox Mike Fiore is born in Brooklyn, NY. |
| Friday, November 17 |
| Future Red Sox Tom Seaver is born in Fresno, CA. |
| Tuesday, November 28 |
| Former Red Sox Elmer Miller dies in Beloit, WI at the age of 55. |
| Wednesday, December 6 |
| Future Red Sox Tony Horton is born in Santa Monica, CA. |
| Sunday, December 10 |
| Future Red Sox Steve Renko is born in Kansas City, KS. |
| Monday, December 18 |
| Future Red Sox Syd O'Brien is born in Compton, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |