| Thursday, January 13 |
| Future Cardinal Larry Jaster is born in Midland, MI. |
| Thursday, January 20 |
| Future Cardinal Carl Taylor is born in Sarasota, FL. |
| Saturday, February 19 |
| Future Cardinal Chris Zachary is born in Knoxville, TN. |
| Wednesday, February 23 |
| Future Cardinal Don Shaw is born in Pittsburgh, PA. |
| Wednesday, March 15 |
| Future Cardinal Wayne Granger is born in Springfield, MA. |
| Sunday, March 19 |
| Former Cardinal John Kelly dies in Baltimore, MD at the age of 66. |
| Tuesday, April 11 |
| Former Cardinal Jack Dunleavy dies in S.Norwalk, CT at the age of 65. |
| Friday, April 14 |
| Future Cardinal Frank Bertaina is born in San Francisco, CA. |
| Tuesday, April 18 |
| » Defeated Pirates (0-1), 2-0 | Sportsman's Park III (1-0) | 1-0 | |
| » Starters: Preacher Roe vs Max Lanier | First | -- |
| Thursday, April 20 |
| » Defeated Pirates (0-2), 5-3 | Sportsman's Park III (2-0) | 2-0 | Won 2 |
| » Starters: Cookie Cuccurullo vs Mort Cooper | Second | ½ out |
| Friday, April 21 |
| » Defeated Cubs (1-3), 4-0 | Wrigley Field (1-0) | 3-0 | Won 3 |
| » Starters: Harry Brecheen vs Paul Derringer | Second | ½ out |
| Sunday, April 23 |
| » Defeated Cubs (1-4), 11-3 | Wrigley Field (2-0) | 4-0 | Won 4 |
| » Starters: Max Lanier vs Hank Wyse | First | -- |
| » Defeated Cubs (1-5), 5-4 | Wrigley Field (3-0) | 5-0 | Won 5 |
| » Starters: Harry Gumbert vs Ed Hanyzewski | First | -- |
| Tuesday, April 25 |
| » Lost to Reds (4-1), 10-3 | Crosley Field (0-1) | 5-1 | |
| » Starters: Mort Cooper vs Elmer Riddle | First | -- |
| » Major-league debuts: Freddy Schmidt and Ted Wilks (Cardinals) |
| Future Cardinal Joe Hague is born in Huntington, WV. |
| Wednesday, April 26 |
| » Lost to Reds (5-1), 1-0 | Crosley Field (0-2) | 5-2 | Lost 2 |
| » Starters: Al Jurisich vs Bucky Walters | Second | ½ out |
| » Major-league debuts: Al Jurisich (Cardinals) |
| Thursday, April 27 |
| » Defeated Reds (5-2), 3-2 | Crosley Field (1-2) | 6-2 | |
| » Starters: Red Munger vs Tommy DeLa Cruz | Second | 1 out |
| Saturday, April 29 |
| » Defeated Cubs (1-7), 4-2 | Sportsman's Park III (3-0) | 7-2 | Won 2 |
| » Starters: Paul Derringer vs Harry Brecheen | First | -- |
| Sunday, April 30 |
| » Defeated Cubs (1-8), 5-0 | Sportsman's Park III (4-0) | 8-2 | Won 3 |
| » Starters: Ed Hanyzewski vs Max Lanier | First | -- |
| » Defeated Cubs (1-9), 7-5 | Sportsman's Park III (5-0) | 9-2 | Won 4 |
| » Starters: Hank Wyse vs Ted Wilks | First | -- |
| Monday, May 1 |
| » Major-league debuts: Joe Wood (Red Sox) |
| Tuesday, May 2 |
| » Lost to Pirates (4-5), 3-1 | Forbes Field (0-1) | 9-3 | |
| » Starters: Al Jurisich vs Preacher Roe | First | -- |
| Wednesday, May 3 |
| » Defeated Pirates (4-6), 5-1 | Forbes Field (1-1) | 10-3 | |
| » Starters: Harry Gumbert vs Rip Sewell | First | -- |
| Thursday, May 4 |
| » Lost to Pirates (5-6), 6-3 | Forbes Field (1-2) | 10-4 | |
| » Starters: Mort Cooper vs Max Butcher | First | -- |
| Saturday, May 6 |
| » Lost to Reds (9-4), 2-0 | Sportsman's Park III (5-1) | 10-5 | Lost 2 |
| » Starters: Bucky Walters vs Red Munger | Second | 1 out |
| » Major-league debuts: Blix Donnelly (Cardinals) |
| Sunday, May 7 |
| » Defeated Reds (9-5), 5-1 | Sportsman's Park III (6-1) | 11-5 | |
| » Starters: Elmer Riddle vs Max Lanier | First | -- |
| » Defeated Reds (9-6), 1-0 | Sportsman's Park III (7-1) | 12-5 | Won 2 |
| » Starters: Tommy DeLa Cruz vs Al Jurisich | First | -- |
| Wednesday, May 10 |
| » Defeated Dodgers (8-8), 4-2 | Sportsman's Park III (8-1) | 13-5 | Won 3 |
| » Starters: Whit Wyatt vs Mort Cooper | First | -- |
| Thursday, May 11 |
| » Lost to Dodgers (9-8), 2-1 | Sportsman's Park III (8-2) | 13-6 | |
| » Starters: Curt Davis vs Harry Gumbert | First | -- |
| Friday, May 12 |
| » Defeated Dodgers (9-9), 7-2 | Sportsman's Park III (9-2) | 14-6 | |
| » Starters: Hal Gregg vs Max Lanier | First | -- |
| Saturday, May 13 |
| » Defeated Dodgers (9-10), 8-4 | Sportsman's Park III (10-2) | 15-6 | Won 2 |
| » Starters: Rube Melton vs Harry Brecheen | First | -- |
| Sunday, May 14 |
| » Defeated Phillies (12-7), 6-3 | Sportsman's Park III (11-2) | 16-6 | Won 3 |
| » Starters: Ken Raffensberger vs Mort Cooper | First | -- |
| » Defeated Phillies (12-8), 1-0 | Sportsman's Park III (12-2) | 17-6 | Won 4 |
| » Starters: Al Gerheauser vs Red Munger | First | -- |
| Monday, May 15 |
| » Defeated Phillies (12-9), 11-6 | Sportsman's Park III (13-2) | 18-6 | Won 5 |
| » Starters: Dick Barrett vs Harry Gumbert | First | -- |
| Tuesday, May 16 |
| » Game at Sportsman's Park III interrupted in the 8th inning with the score of Phillies 6, Cardinals 4. Completed on June 28. |
| Wednesday, May 17 |
| » Lost to Braves (13-14), 5-1 | Sportsman's Park III (13-3) | 18-7 | |
| » Starters: Red Barrett vs Harry Brecheen | First | -- |
| Thursday, May 18 |
| » Defeated Braves (13-15), 2-0 | Sportsman's Park III (14-3) | 19-7 | |
| » Starters: Al Javery vs Red Munger | First | -- |
| Friday, May 19 |
| » Lost to Braves (14-15), 4-3 | Sportsman's Park III (14-4) | 19-8 | |
| » Starters: Jim Tobin vs Mort Cooper | First | -- |
| Saturday, May 20 |
| » Defeated Giants (12-15), 10-0 | Sportsman's Park III (15-4) | 20-8 | |
| » Starters: Bill Voiselle vs Max Lanier | First | -- |
| Sunday, May 21 |
| » Defeated Giants (12-16), 10-3 | Sportsman's Park III (16-4) | 21-8 | Won 2 |
| » Starters: Rube Fischer vs Harry Brecheen | First | -- |
| » Lost to Giants (13-16), 7-5 | Sportsman's Park III (16-5) | 21-9 | |
| » Starters: Ewald Pyle vs Al Jurisich | First | -- |
| Friday, May 26 |
| » Defeated Dodgers (13-18), 5-3 | Ebbets Field (1-0) | 22-9 | |
| » Starters: Max Lanier vs Hal Gregg | First | -- |
| Saturday, May 27 |
| » Defeated Giants (13-19), 6-4 | Polo Grounds V (1-0) | 23-9 | Won 2 |
| » Starters: Red Munger vs Cliff Melton | First | -- |
| Sunday, May 28 |
| » Defeated Giants (13-20), 8-0 | Polo Grounds V (2-0) | 24-9 | Won 3 |
| » Starters: Mort Cooper vs Ewald Pyle | First | -- |
| » Lost to Giants (14-20), 3-1 | Polo Grounds V (2-1) | 24-10 | |
| » Starters: Ted Wilks vs Bill Voiselle | First | -- |
| Monday, May 29 |
| » Lost to Giants (15-20), 6-4 | Polo Grounds V (2-2) | 24-11 | Lost 2 |
| » Starters: Al Jurisich vs Rube Fischer | First | -- |
| Tuesday, May 30 |
| » Lost to Braves (18-21), 1-0 | Braves Field (0-1) | 24-12 | Lost 3 |
| » Starters: Harry Gumbert vs Nate Andrews | First | -- |
| » Defeated Braves (18-22), 13-3 | Braves Field (1-1) | 25-12 | |
| » Starters: Harry Brecheen vs Ira Hutchinson | First | -- |
| Wednesday, May 31 |
| » Lost to Braves (19-22), 5-1 | Braves Field (1-2) | 25-13 | |
| » Starters: Max Lanier vs Red Barrett | First | -- |
| Thursday, June 1 |
| » Defeated Braves (19-23), 4-2 | Braves Field (2-2) | 26-13 | |
| » Starters: Red Munger vs Al Javery | First | -- |
| Friday, June 2 |
| » Defeated Phillies (17-20), 9-3 | Shibe Park (1-0) | 27-13 | Won 2 |
| » Starters: Mort Cooper vs Ken Raffensberger | First | -- |
| Saturday, June 3 |
| » Defeated Phillies (17-21), 5-3 | Shibe Park (2-0) | 28-13 | Won 3 |
| » Starters: Ted Wilks vs Al Gerheauser | First | -- |
| Sunday, June 4 |
| » Defeated Phillies (17-22), 4-2 | Shibe Park (3-0) | 29-13 | Won 4 |
| » Starters: Harry Gumbert vs Charley Schanz | First | -- |
| » Lost to Phillies (18-22), 1-0 | Shibe Park (3-1) | 29-14 | |
| » Starters: Freddy Schmidt vs Bill Lee | First | -- |
| Thursday, June 8 |
| » Lost to Reds (25-19), 2-1 | Crosley Field (1-3) | 29-15 | Lost 2 |
| » Starters: Max Lanier vs Bucky Walters | First | -- |
| Saturday, June 10 |
| » Defeated Reds (25-20), 18-0 | Crosley Field (2-3) | 30-15 | |
| » Starters: Mort Cooper vs Bill Lohrman | First | -- |
| » Major-league debuts: Joe Nuxhall (Reds) |
| Sunday, June 11 |
| » Defeated Reds (25-21), 3-1 | Crosley Field (3-3) | 31-15 | Won 2 |
| » Starters: Red Munger vs Arnold Carter | First | -- |
| » Defeated Reds (25-22), 4-1 | Crosley Field (4-3) | 32-15 | Won 3 |
| » Starters: Harry Gumbert vs Clyde Shoun | First | -- |
| Monday, June 12 |
| » Major-league debuts: Ralph Branca (Dodgers) |
| Tuesday, June 13 |
| » Defeated Cubs (16-27), 8-3 | Sportsman's Park III (17-5) | 33-15 | Won 4 |
| » Starters: Claude Passeau vs Max Lanier | First | -- |
| Wednesday, June 14 |
| » Defeated Cubs (16-28), 10-9 | Sportsman's Park III (18-5) | 34-15 | Won 5 |
| » Starters: Hank Wyse vs Mort Cooper | First | -- |
| Saturday, June 17 |
| » Defeated Pirates (27-22), 2-1 | Sportsman's Park III (19-5) | 35-15 | Won 6 |
| » Starters: Preacher Roe vs Red Munger | First | -- |
| Sunday, June 18 |
| » Defeated Pirates (27-23), 12-2 | Sportsman's Park III (20-5) | 36-15 | Won 7 |
| » Starters: Rip Sewell vs Mort Cooper | First | -- |
| » Lost to Pirates (28-23), 3-1 | Sportsman's Park III (20-6) | 36-16 | |
| » Starters: Fritz Ostermueller vs Max Lanier | First | -- |
| Tuesday, June 20 |
| » Defeated Cubs (17-31), 2-1 | Wrigley Field (4-0) | 37-16 | |
| » Starters: Al Jurisich vs Bob Chipman | First | -- |
| Wednesday, June 21 |
| » Defeated Cubs (17-32), 6-4 | Wrigley Field (5-0) | 38-16 | Won 2 |
| » Starters: Red Munger vs Paul Erickson | First | -- |
| » Defeated Cubs (17-33), 7-2 | Wrigley Field (6-0) | 39-16 | Won 3 |
| » Starters: Harry Brecheen vs Claude Passeau | First | -- |
| Friday, June 23 |
| » Tied Pirates, 5-5 | Forbes Field (1-2) | 39-16 | |
| » Starters: Max Lanier vs Preacher Roe | First | -- |
| Saturday, June 24 |
| » Defeated Pirates (31-25), 16-0 | Forbes Field (2-2) | 40-16 | Won 4 |
| » Starters: Mort Cooper vs Fritz Ostermueller | First | -- |
| Sunday, June 25 |
| » Defeated Pirates (31-26), 2-1 | Forbes Field (3-2) | 41-16 | Won 5 |
| » Starters: Red Munger vs Rip Sewell | First | -- |
| » Tied Pirates, 5-5 | Forbes Field (3-2) | 41-16 | |
| » Starters: Al Jurisich vs Ray Starr | First | -- |
| Wednesday, June 28 |
| » Lost to Phillies (24-35), 6-5 | Sportsman's Park III (20-7) | 41-17 | |
| » Starters: Charley Schanz vs Max Lanier | First | -- |
| » Lost to Phillies (25-35), 4-0 | Sportsman's Park III (20-8) | 41-18 | Lost 2 |
| » Starters: Ken Raffensberger vs Max Lanier | First | -- |
| Thursday, June 29 |
| » Lost to Phillies (26-35), 1-0 | Sportsman's Park III (20-9) | 41-19 | Lost 3 |
| » Starters: Bill Lee vs Red Munger | First | -- |
| Friday, June 30 |
| » Defeated Phillies (26-36), 8-4 | Sportsman's Park III (21-9) | 42-19 | |
| » Starters: Al Gerheauser vs Mort Cooper | First | -- |
| Saturday, July 1 |
| » Defeated Dodgers (33-34), 8-3 | Sportsman's Park III (22-9) | 43-19 | Won 2 |
| » Starters: Curt Davis vs Al Jurisich | First | -- |
| Sunday, July 2 |
| » Defeated Dodgers (33-35), 2-1 | Sportsman's Park III (23-9) | 44-19 | Won 3 |
| » Starters: Rube Melton vs Max Lanier | First | -- |
| » Defeated Dodgers (33-36), 4-2 | Sportsman's Park III (24-9) | 45-19 | Won 4 |
| » Starters: Cal McLish vs Ted Wilks | First | -- |
| Tuesday, July 4 |
| » Defeated Giants (34-34), 6-2 | Sportsman's Park III (25-9) | 46-19 | Won 5 |
| » Starters: Harry Feldman vs Mort Cooper | First | -- |
| » Defeated Giants (34-35), 9-1 | Sportsman's Park III (26-9) | 47-19 | Won 6 |
| » Starters: Rube Fischer vs Harry Brecheen | First | -- |
| Wednesday, July 5 |
| » Defeated Giants (34-36), 4-1 | Sportsman's Park III (27-9) | 48-19 | Won 7 |
| » Starters: Andy Hansen vs Red Munger | First | -- |
| Thursday, July 6 |
| » Lost to Giants (35-36), 10-1 | Sportsman's Park III (27-10) | 48-20 | |
| » Starters: Bill Voiselle vs Al Jurisich | First | -- |
| Friday, July 7 |
| » Lost to Braves (30-44), 10-5 | Sportsman's Park III (27-11) | 48-21 | Lost 2 |
| » Starters: Nate Andrews vs Max Lanier | First | -- |
| Saturday, July 8 |
| » Defeated Braves (30-45), 4-0 | Sportsman's Park III (28-11) | 49-21 | |
| » Starters: Red Barrett vs Ted Wilks | First | -- |
| Sunday, July 9 |
| » Defeated Braves (30-46), 1-0 | Sportsman's Park III (29-11) | 50-21 | Won 2 |
| » Starters: Jim Tobin vs Mort Cooper | First | -- |
| » Defeated Braves (30-47), 9-0 | Sportsman's Park III (30-11) | 51-21 | Won 3 |
| » Starters: Al Javery vs Harry Brecheen | First | -- |
| Thursday, July 13 |
| » Defeated Reds (42-34), 3-2 | Sportsman's Park III (31-11) | 52-21 | Won 4 |
| » Starters: Jim Konstanty vs Al Jurisich | First | -- |
| Friday, July 14 |
| » Lost to Reds (43-34), 3-0 | Sportsman's Park III (31-12) | 52-22 | |
| » Starters: Bucky Walters vs Mort Cooper | First | -- |
| Future Cardinal Billy McCool is born in Batesville, IN. |
| Saturday, July 15 |
| » Defeated Reds (43-35), 12-1 | Sportsman's Park III (32-12) | 53-22 | |
| » Starters: Harry Gumbert vs Ted Wilks | First | -- |
| » Major-league debuts: Kent Peterson (Reds) |
| Sunday, July 16 |
| » Defeated Reds (43-36), 4-2 | Sportsman's Park III (33-12) | 54-22 | Won 2 |
| » Starters: Arnold Carter vs Blix Donnelly | First | -- |
| » Lost to Reds (44-36), 3-2 | Sportsman's Park III (33-13) | 54-23 | |
| » Starters: Ed Heusser vs Harry Brecheen | First | -- |
| Tuesday, July 18 |
| » Defeated Dodgers (34-47), 5-0 | Ebbets Field (2-0) | 55-23 | |
| » Starters: Max Lanier vs Hal Gregg | First | -- |
| Thursday, July 20 |
| » Defeated Giants (40-41), 10-2 | Polo Grounds V (3-2) | 56-23 | Won 2 |
| » Starters: Mort Cooper vs Jack Brewer | First | -- |
| » Defeated Giants (40-42), 6-2 | Polo Grounds V (4-2) | 57-23 | Won 3 |
| » Starters: Ted Wilks vs Rube Fischer | First | -- |
| Friday, July 21 |
| » Defeated Giants (40-43), 5-0 | Polo Grounds V (5-2) | 58-23 | Won 4 |
| » Starters: Harry Brecheen vs Harry Feldman | First | -- |
| Saturday, July 22 |
| » Lost to Braves (36-49), 6-5 | Braves Field (2-3) | 58-24 | |
| » Starters: Blix Donnelly vs Red Barrett | First | -- |
| Sunday, July 23 |
| » Defeated Braves (36-50), 3-2 | Braves Field (3-3) | 59-24 | |
| » Starters: Max Lanier vs Nate Andrews | First | -- |
| » Defeated Braves (36-51), 5-2 | Braves Field (4-3) | 60-24 | Won 2 |
| » Starters: Mort Cooper vs Al Javery | First | -- |
| Monday, July 24 |
| » Defeated Braves (36-52), 7-1 | Braves Field (5-3) | 61-24 | Won 3 |
| » Starters: Ted Wilks vs Jim Tobin | First | -- |
| Tuesday, July 25 |
| » Defeated Phillies (36-48), 9-0 | Shibe Park (4-1) | 62-24 | Won 4 |
| » Starters: Al Jurisich vs Al Gerheauser | First | -- |
| » Major-league debuts: Bob Keely (Cardinals) |
| Future Cardinal Buddy Bradford is born in Mobile, AL. |
| Wednesday, July 26 |
| » Defeated Phillies (36-49), 8-6 | Shibe Park (5-1) | 63-24 | Won 5 |
| » Starters: Freddy Schmidt vs Charley Schanz | First | -- |
| Thursday, July 27 |
| » Defeated Phillies (36-50), 8-7 | Shibe Park (6-1) | 64-24 | Won 6 |
| » Starters: Harry Brecheen vs Bill Lee | First | -- |
| » Defeated Phillies (36-51), 5-0 | Shibe Park (7-1) | 65-24 | Won 7 |
| » Starters: Mort Cooper vs Ken Raffensberger | First | -- |
| Saturday, July 29 |
| » Defeated Dodgers (36-56), 14-2 | Ebbets Field (3-0) | 66-24 | Won 8 |
| » Starters: Max Lanier vs Les Webber | First | -- |
| » Defeated Dodgers (36-57), 12-7 | Ebbets Field (4-0) | 67-24 | Won 9 |
| » Starters: Ted Wilks vs Hal Gregg | First | -- |
| Sunday, July 30 |
| » Lost to Dodgers (37-57), 10-4 | Ebbets Field (4-1) | 67-25 | |
| » Starters: Al Jurisich vs Tommy Warren | First | -- |
| » Defeated Dodgers (37-58), 9-7 | Ebbets Field (5-1) | 68-25 | |
| » Starters: Blix Donnelly vs Cal McLish | First | -- |
| Monday, July 31 |
| » Lost to Dodgers (38-58), 6-1 | Ebbets Field (5-2) | 68-26 | |
| » Starters: Mort Cooper vs Hal Gregg | First | -- |
| Tuesday, August 1 |
| » Defeated Dodgers (38-59), 14-3 | Ebbets Field (6-2) | 69-26 | |
| » Starters: Mort Cooper vs Whit Wyatt | First | -- |
| Wednesday, August 2 |
| » Defeated Pirates (53-41), 8-4 | Forbes Field (4-2) | 70-26 | Won 2 |
| » Starters: Max Lanier vs Rip Sewell | First | -- |
| Thursday, August 3 |
| » Defeated Pirates (53-42), 15-2 | Forbes Field (5-2) | 71-26 | Won 3 |
| » Starters: Ted Wilks vs Preacher Roe | First | -- |
| Friday, August 4 |
| » Lost to Reds (55-42), 5-3 | Crosley Field (4-4) | 71-27 | |
| » Starters: Al Jurisich vs Bucky Walters | First | -- |
| Future Cardinal Rich Nye is born in Oakland, CA. |
| Sunday, August 6 |
| » Defeated Reds (55-43), 5-4 | Crosley Field (5-4) | 72-27 | |
| » Starters: Mort Cooper vs Ed Heusser | First | -- |
| Wednesday, August 9 |
| » Defeated Phillies (37-59), 4-2 | Sportsman's Park III (34-13) | 73-27 | Won 2 |
| » Starters: Ken Raffensberger vs Harry Brecheen | First | -- |
| Thursday, August 10 |
| » Defeated Phillies (37-60), 2-0 | Sportsman's Park III (35-13) | 74-27 | Won 3 |
| » Starters: Al Gerheauser vs Mort Cooper | First | -- |
| Friday, August 11 |
| » Defeated Phillies (37-61), 9-4 | Sportsman's Park III (36-13) | 75-27 | Won 4 |
| » Starters: Charley Schanz vs Ted Wilks | First | -- |
| Saturday, August 12 |
| » Lost to Phillies (38-61), 3-0 | Sportsman's Park III (36-14) | 75-28 | |
| » Starters: Dick Barrett vs Al Jurisich | First | -- |
| Sunday, August 13 |
| » Defeated Dodgers (43-65), 4-1 | Sportsman's Park III (37-14) | 76-28 | |
| » Starters: Tom Sunkel vs Max Lanier | First | -- |
| » Defeated Dodgers (43-66), 7-3 | Sportsman's Park III (38-14) | 77-28 | Won 2 |
| » Starters: Cal McLish vs Harry Brecheen | First | -- |
| Monday, August 14 |
| » Defeated Dodgers (43-67), 4-2 | Sportsman's Park III (39-14) | 78-28 | Won 3 |
| » Starters: Hal Gregg vs Mort Cooper | First | -- |
| Tuesday, August 15 |
| » Defeated Dodgers (43-68), 6-3 | Sportsman's Park III (40-14) | 79-28 | Won 4 |
| » Starters: Les Webber vs Ted Wilks | First | -- |
| Wednesday, August 16 |
| » Defeated Giants (50-60), 5-0 | Sportsman's Park III (41-14) | 80-28 | Won 5 |
| » Starters: Bill Voiselle vs Freddy Schmidt | First | -- |
| Thursday, August 17 |
| » Defeated Giants (50-61), 7-0 | Sportsman's Park III (42-14) | 81-28 | Won 6 |
| » Starters: Ewald Pyle vs Max Lanier | First | -- |
| Friday, August 18 |
| » Defeated Giants (50-62), 5-2 | Sportsman's Park III (43-14) | 82-28 | Won 7 |
| » Starters: Rube Fischer vs Harry Brecheen | First | -- |
| Saturday, August 19 |
| » Defeated Giants (50-63), 8-4 | Sportsman's Park III (44-14) | 83-28 | Won 8 |
| » Starters: Andy Hansen vs Mort Cooper | First | -- |
| Sunday, August 20 |
| » Defeated Braves (45-69), 15-5 | Sportsman's Park III (45-14) | 84-28 | Won 9 |
| » Starters: Johnny Hutchings vs Ted Wilks | First | -- |
| » Lost to Braves (46-69), 5-3 | Sportsman's Park III (45-15) | 84-29 | |
| » Starters: Woody Rich vs Freddy Schmidt | First | -- |
| Tuesday, August 22 |
| » Defeated Braves (46-70), 7-4 | Sportsman's Park III (46-15) | 85-29 | |
| » Starters: Jim Tobin vs Harry Brecheen | First | -- |
| » Defeated Braves (46-71), 2-1 | Sportsman's Park III (47-15) | 86-29 | Won 2 |
| » Starters: Al Javery vs Max Lanier | First | -- |
| Wednesday, August 23 |
| » Defeated Cubs (51-61), 11-1 | Sportsman's Park III (48-15) | 87-29 | Won 3 |
| » Starters: Bob Chipman vs Mort Cooper | First | -- |
| Thursday, August 24 |
| » Defeated Cubs (51-62), 2-1 | Sportsman's Park III (49-15) | 88-29 | Won 4 |
| » Starters: Claude Passeau vs Ted Wilks | First | -- |
| Friday, August 25 |
| » Defeated Pirates (70-47), 4-0 | Sportsman's Park III (50-15) | 89-29 | Won 5 |
| » Starters: Preacher Roe vs Freddy Schmidt | First | -- |
| Sunday, August 27 |
| » Lost to Pirates (71-47), 14-6 | Sportsman's Park III (50-16) | 89-30 | |
| » Starters: Nick Strincevich vs Max Lanier | First | -- |
| » Tied Pirates, 1-1 | Sportsman's Park III (50-16) | 89-30 | |
| » Starters: Fritz Ostermueller vs Harry Brecheen | First | -- |
| Monday, August 28 |
| » Defeated Reds (67-50), 3-2 | Sportsman's Park III (51-16) | 90-30 | |
| » Starters: Harry Gumbert vs Mort Cooper | First | -- |
| Tuesday, August 29 |
| » Defeated Reds (67-51), 3-0 | Sportsman's Park III (52-16) | 91-30 | Won 2 |
| » Starters: Tommy DeLa Cruz vs Ted Wilks | First | -- |
| Friday, September 1 |
| » Lost to Pirates (73-50), 3-2 | Forbes Field (5-3) | 91-31 | |
| » Starters: Max Lanier vs Fritz Ostermueller | First | -- |
| Saturday, September 2 |
| » Lost to Pirates (74-50), 5-4 | Forbes Field (5-4) | 91-32 | Lost 2 |
| » Starters: Freddy Schmidt vs Preacher Roe | First | -- |
| Sunday, September 3 |
| » Lost to Pirates (75-50), 6-5 | Forbes Field (5-5) | 91-33 | Lost 3 |
| » Starters: Mort Cooper vs Rip Sewell | First | -- |
| » Lost to Pirates (76-50), 8-2 | Forbes Field (5-6) | 91-34 | Lost 4 |
| » Starters: Harry Brecheen vs Nick Strincevich | First | -- |
| Monday, September 4 |
| » Defeated Reds (68-55), 3-0 | Crosley Field (6-4) | 92-34 | |
| » Starters: Ted Wilks vs Harry Gumbert | First | -- |
| Tuesday, September 5 |
| » Defeated Reds (68-56), 4-0 | Crosley Field (7-4) | 93-34 | Won 2 |
| » Starters: Mort Cooper vs Tommy DeLa Cruz | First | -- |
| » Lost to Reds (69-56), 4-0 | Crosley Field (7-5) | 93-35 | |
| » Starters: Max Lanier vs Bucky Walters | First | -- |
| Thursday, September 7 |
| » Defeated Cubs (58-68), 3-2 | Sportsman's Park III (53-16) | 94-35 | |
| » Starters: Bob Chipman vs Harry Brecheen | First | -- |
| Future Cardinal Barry Lersch is born in Denver, CO. |
| Saturday, September 9 |
| » Lost to Cubs (59-68), 6-1 | Sportsman's Park III (53-17) | 94-36 | |
| » Starters: Claude Passeau vs Ted Wilks | First | -- |
| Sunday, September 10 |
| » Lost to Cubs (60-68), 9-0 | Sportsman's Park III (53-18) | 94-37 | Lost 2 |
| » Starters: Paul Erickson vs Max Lanier | First | -- |
| » Defeated Cubs (60-69), 4-2 | Sportsman's Park III (54-18) | 95-37 | |
| » Starters: Paul Derringer vs Mort Cooper | First | -- |
| Tuesday, September 12 |
| » Lost to Pirates (79-54), 5-3 | Sportsman's Park III (54-19) | 95-38 | |
| » Starters: Fritz Ostermueller vs Freddy Schmidt | First | -- |
| » Lost to Pirates (80-54), 6-5 | Sportsman's Park III (54-20) | 95-39 | Lost 2 |
| » Starters: Preacher Roe vs Bud Byerly | First | -- |
| Wednesday, September 13 |
| » Lost to Pirates (81-54), 7-3 | Sportsman's Park III (54-21) | 95-40 | Lost 3 |
| » Starters: Rip Sewell vs Harry Brecheen | First | -- |
| » Lost to Pirates (82-54), 10-5 | Sportsman's Park III (54-22) | 95-41 | Lost 4 |
| » Starters: Xavier Rescigno vs Max Lanier | First | -- |
| Friday, September 15 |
| » Lost to Cubs (63-72), 2-1 | Wrigley Field (6-1) | 95-42 | Lost 5 |
| » Starters: Mort Cooper vs Bob Chipman | First | -- |
| » Defeated Cubs (63-73), 3-2 | Wrigley Field (7-1) | 96-42 | |
| » Starters: Ted Wilks vs Hy Vandenberg | First | -- |
| Saturday, September 16 |
| » Lost to Cubs (64-73), 9-5 | Wrigley Field (7-2) | 96-43 | |
| » Starters: Bill Trotter vs Red Lynn | First | -- |
| Sunday, September 17 |
| » Lost to Cubs (65-73), 2-1 | Wrigley Field (7-3) | 96-44 | Lost 2 |
| » Starters: Max Lanier vs Hank Wyse | First | -- |
| » Lost to Cubs (66-73), 2-1 | Wrigley Field (7-4) | 96-45 | Lost 3 |
| » Starters: Harry Brecheen vs Claude Passeau | First | -- |
| Thursday, September 21 |
| » Defeated Braves (58-84), 5-4 | Braves Field (6-3) | 97-45 | |
| » Starters: Mort Cooper vs Red Barrett | First | -- |
| » Defeated Braves (58-85), 6-5 | Braves Field (7-3) | 98-45 | Won 2 |
| » Starters: Ted Wilks vs Jim Tobin | First | -- |
| Friday, September 22 |
| » Lost to Braves (59-85), 11-2 | Braves Field (7-4) | 98-46 | |
| » Starters: Max Lanier vs Nate Andrews | First | -- |
| Saturday, September 23 |
| » Defeated Phillies (58-85), 6-2 | Shibe Park (8-1) | 99-46 | |
| » Starters: Bud Byerly vs Bill Lee | First | -- |
| Sunday, September 24 |
| » Defeated Phillies (58-86), 4-3 | Shibe Park (9-1) | 100-46 | Won 2 |
| » Starters: Mort Cooper vs Ken Raffensberger | First | -- |
| » Defeated Phillies (58-87), 1-0 | Shibe Park (10-1) | 101-46 | Won 3 |
| » Starters: Ted Wilks vs Charley Schanz | First | -- |
| Monday, September 25 |
| » Defeated Dodgers (60-88), 3-1 | Ebbets Field (7-2) | 102-46 | Won 4 |
| » Starters: Harry Brecheen vs Rube Melton | First | -- |
| Tuesday, September 26 |
| » Defeated Dodgers (60-89), 8-7 | Ebbets Field (8-2) | 103-46 | Won 5 |
| » Starters: Freddy Schmidt vs Hal Gregg | First | -- |
| Wednesday, September 27 |
| » Lost to Dodgers (61-89), 3-2 | Ebbets Field (8-3) | 103-47 | |
| » Starters: Bud Byerly vs Clyde King | First | -- |
| Future Cardinal Gary Sutherland is born in Glendale, CA. |
| Thursday, September 28 |
| » Defeated Giants (65-86), 2-0 | Polo Grounds V (6-2) | 104-47 | |
| » Starters: Blix Donnelly vs Ewald Pyle | First | -- |
| Friday, September 29 |
| » Lost to Giants (66-86), 3-2 | Polo Grounds V (6-3) | 104-48 | |
| » Starters: Ted Wilks vs Cliff Melton | First | -- |
| Sunday, October 1 |
| » Lost to Giants (67-86), 6-5 | Polo Grounds V (6-4) | 104-49 | Lost 2 |
| » Starters: Bud Byerly vs Bill Voiselle | First | -- |
| » Defeated Giants (67-87), 10-6 | Polo Grounds V (7-4) | 105-49 | |
| » Starters: Freddy Schmidt vs Ken Brondell | First | -- |
| Wednesday, October 11 |
| Future Cardinal Mike Fiore is born in Brooklyn, NY. |
| Sunday, October 29 |
| Future Cardinal Jim Bibby is born in Franklinton, NC. |
| Tuesday, November 28 |
| Former Cardinal Elmer Miller dies in Beloit, WI at the age of 55. |
| Monday, December 4 |
| Former Cardinal Roger Bresnahan dies in Toledo, OH at the age of 66. |
| Friday, December 22 |
| Future Cardinal Steve Carlton is born in Miami, FL. |
Game information provided by Retrosheet (www.retrosheet.org) |
