| Friday, February 19 |
| Future White Sox Gail Hopkins is born in Tulsa, OK. |
| Tuesday, March 16 |
| Future White Sox Rick Reichardt is born in Madison, WI. |
| Tuesday, March 23 |
| Future White Sox Bruce Howard is born in Salisbury, MD. |
| Saturday, April 3 |
| Future White Sox Barry Moore is born in Statesville, NC. |
| Monday, April 12 |
| Future White Sox Vincente Romo is born in Santa Rosalia, Mexico. |
| Wednesday, April 21 |
| » Lost to Browns (1-0), 3-0 | Sportsman's Park III (0-1) | 0-1 | |
| » Starters: Bill Dietrich vs Al Hollingsworth | Third | 1 out |
| » Major-league debuts: Milt Byrnes (Browns) Guy Curtright (White Sox) |
| Friday, April 23 |
| » Major-league debuts: Tom McBride and Roy Partee (Red Sox) |
| Saturday, April 24 |
| » Defeated Browns (1-1), 3-1 | Sportsman's Park III (1-1) | 1-1 | |
| » Starters: Eddie Smith vs Denny Galehouse | Third | 1 out |
| Sunday, April 25 |
| » Lost to Browns (2-1), 5-1 | Sportsman's Park III (1-2) | 1-2 | |
| » Starters: Bill Swift vs Johnny Niggeling | Fifth | 2 out |
| Tuesday, April 27 |
| » Lost to Indians (4-2), 4-2 | Comiskey Park I (0-1) | 1-3 | Lost 2 |
| » Starters: Mel Harder vs Thornton Lee | Seventh | 2 out |
| » Major-league debuts: Gordon Malzberger (White Sox) |
| Wednesday, April 28 |
| » Lost to Indians (5-2), 2-0 | Comiskey Park I (0-2) | 1-4 | Lost 3 |
| » Starters: Al Smith vs Bill Dietrich | Eighth | 3 out |
| Saturday, May 1 |
| » Defeated Browns (2-4), 5-4 | Comiskey Park I (1-2) | 2-4 | |
| » Starters: Denny Galehouse vs Eddie Smith | Fifth | 3 out |
| Sunday, May 2 |
| » Lost to Browns (3-4), 3-2 | Comiskey Park I (1-3) | 2-5 | |
| » Starters: Johnny Niggeling vs Thornton Lee | Eighth | 4 out |
| » Lost to Browns (4-4), 5-1 | Comiskey Park I (1-4) | 2-6 | Lost 2 |
| » Starters: Steve Sundra vs Johnny Humphries | Eighth | 4 out |
| Tuesday, May 4 |
| » Lost to Indians (7-3), 2-1 | League Park II (0-1) | 2-7 | Lost 3 |
| » Starters: Bill Dietrich vs Jim Bagby | Eighth | 5 out |
| Wednesday, May 5 |
| » Lost to Indians (8-3), 2-1 | League Park II (0-2) | 2-8 | Lost 4 |
| » Starters: Eddie Smith vs Chubby Dean | Eighth | 5½ out |
| » Defeated Indians (8-4), 5-2 | League Park II (1-2) | 3-8 | |
| » Starters: Buck Ross vs Al Milnar | Eighth | 5½ out |
| Thursday, May 6 |
| » Lost to Indians (9-4), 6-3 | League Park II (1-3) | 3-9 | |
| » Starters: Jake Wade vs Al Smith | Eighth | 7 out |
| Friday, May 7 |
| » Defeated Tigers (7-6), 1-0 | Comiskey Park I (2-4) | 4-9 | |
| » Starters: Hal White vs Johnny Humphries | Eighth | 7 out |
| Sunday, May 9 |
| » Defeated Tigers (7-7), 3-1 | Comiskey Park I (3-4) | 5-9 | Won 2 |
| » Starters: Virgil Trucks vs Bill Dietrich | Seventh | 6½ out |
| » Lost to Tigers (8-7), 4-1 | Comiskey Park I (3-5) | 5-10 | |
| » Starters: Dizzy Trout vs Eddie Smith | Seventh | 6½ out |
| Wednesday, May 12 |
| » Defeated Yankees (13-6), 2-1 | Comiskey Park I (4-5) | 6-10 | |
| » Starters: Tiny Bonham vs Johnny Humphries | Seventh | 5½ out |
| Friday, May 14 |
| » Defeated Yankees (13-7), 3-0 | Comiskey Park I (5-5) | 7-10 | Won 2 |
| » Starters: Butch Wensloff vs Buck Ross | Seventh | 4½ out |
| Sunday, May 16 |
| » Defeated Red Sox (7-14), 4-2 | Comiskey Park I (6-5) | 8-10 | Won 3 |
| » Starters: Dick Newsome vs Bill Dietrich | Seventh | 4½ out |
| » Lost to Red Sox (8-14), 4-2 | Comiskey Park I (6-6) | 8-11 | |
| » Starters: Lou Lucier vs Johnny Humphries | Seventh | 4½ out |
| » Major-league debuts: Leon Culberson (Red Sox) |
| Friday, May 21 |
| » Defeated Senators (14-12), 1-0 | Comiskey Park I (7-6) | 9-11 | |
| » Starters: Dutch Leonard vs Johnny Humphries | Seventh | 4 out |
| Saturday, May 22 |
| » Defeated Senators (14-13), 5-2 | Comiskey Park I (8-6) | 10-11 | Won 2 |
| » Starters: Ewald Pyle vs Eddie Smith | Sixth | 3 out |
| Future White Sox Tommy John is born in Terre Haute, IN. |
| Sunday, May 23 |
| » Lost to Senators (15-13), 11-0 | Comiskey Park I (8-7) | 10-12 | |
| » Starters: Early Wynn vs Buck Ross | Sixth | 3½ out |
| Thursday, May 27 |
| » Lost to Athletics (15-15), 7-5 | Shibe Park (0-1) | 10-13 | Lost 2 |
| » Starters: Johnny Humphries vs Orie Arntzen | Fifth | 3½ out |
| Friday, May 28 |
| » Lost to Athletics (16-15), 5-2 | Shibe Park (0-2) | 10-14 | Lost 3 |
| » Starters: Buck Ross vs Russ Christopher | Sixth | 4 out |
| Saturday, May 29 |
| » Lost to Senators (18-13), 7-4 | Griffith Stadium (0-1) | 10-15 | Lost 4 |
| » Starters: Eddie Smith vs Alex Carrasquel | Eighth | 5 out |
| Sunday, May 30 |
| » Defeated Senators (18-14), 5-2 | Griffith Stadium (1-1) | 11-15 | |
| » Starters: Bill Dietrich vs Ewald Pyle | Sixth | 4½ out |
| » Defeated Senators (18-15), 5-1 | Griffith Stadium (2-1) | 12-15 | Won 2 |
| » Starters: Thornton Lee vs Lefty Gomez | Sixth | 4½ out |
| Monday, May 31 |
| » Defeated Yankees (18-13), 10-5 | Yankee Stadium (1-0) | 13-15 | Won 3 |
| » Starters: Eddie Smith vs Atley Donald | Seventh | 4½ out |
| » Lost to Yankees (19-13), 10-4 | Yankee Stadium (1-1) | 13-16 | |
| » Starters: Johnny Humphries vs Bill Zuber | Seventh | 4½ out |
| Wednesday, June 2 |
| » Defeated Yankees (19-14), 2-1 | Yankee Stadium (2-1) | 14-16 | |
| » Starters: Jake Wade vs Hank Borowy | Seventh | 3½ out |
| Thursday, June 3 |
| » Defeated Red Sox (18-21), 6-4 | Fenway Park (1-0) | 15-16 | Won 2 |
| » Starters: Joe Haynes vs Dick Newsome | Fifth | 3½ out |
| Friday, June 4 |
| » Defeated Red Sox (18-22), 4-3 | Fenway Park (2-0) | 16-16 | Won 3 |
| » Starters: Buck Ross vs Lou Lucier | Fourth | 3½ out |
| Saturday, June 5 |
| » Defeated Red Sox (18-23), 4-1 | Fenway Park (3-0) | 17-16 | Won 4 |
| » Starters: Thornton Lee vs Tex Hughson | Fourth | 2½ out |
| Sunday, June 6 |
| » Lost to Red Sox (19-23), 4-3 | Fenway Park (3-1) | 17-17 | |
| » Starters: Orval Grove vs Oscar Judd | Fifth | 4½ out |
| » Lost to Red Sox (20-23), 3-2 | Fenway Park (3-2) | 17-18 | Lost 2 |
| » Starters: Jake Wade vs Yank Terry | Fifth | 4½ out |
| Wednesday, June 9 |
| » Defeated Tigers (20-20), 3-1 | Tiger Stadium (1-0) | 18-18 | |
| » Starters: Johnny Humphries vs Hal Newhouser | Fourth | 4 out |
| Thursday, June 10 |
| » Defeated Tigers (20-21), 11-5 | Tiger Stadium (2-0) | 19-18 | Won 2 |
| » Starters: Orval Grove vs Dizzy Trout | Third | 4 out |
| Saturday, June 12 |
| » Lost to Tigers (21-21), 5-3 | Tiger Stadium (2-1) | 19-19 | |
| » Starters: Thornton Lee vs Hal White | Third | 5½ out |
| Sunday, June 13 |
| » Lost to Tigers (22-21), 6-4 | Tiger Stadium (2-2) | 19-20 | Lost 2 |
| » Starters: Bill Dietrich vs Tommy Bridges | Sixth | 5½ out |
| » Lost to Tigers (23-21), 3-2 | Tiger Stadium (2-3) | 19-21 | Lost 3 |
| » Starters: Eddie Smith vs Virgil Trucks | Sixth | 5½ out |
| Tuesday, June 15 |
| » Lost to Browns (18-24), 5-2 | Comiskey Park I (8-8) | 19-22 | Lost 4 |
| » Starters: Steve Sundra vs Johnny Humphries | Fifth | 7 out |
| Wednesday, June 16 |
| » Lost to Browns (19-24), 5-2 | Comiskey Park I (8-9) | 19-23 | Lost 5 |
| » Starters: Denny Galehouse vs Jake Wade | Sixth | 6½ out |
| » Defeated Browns (19-25), 9-0 | Comiskey Park I (9-9) | 20-23 | |
| » Starters: Al Hollingsworth vs Orval Grove | Sixth | 6½ out |
| Thursday, June 17 |
| » Defeated Browns (19-26), 4-3 | Comiskey Park I (10-9) | 21-23 | Won 2 |
| » Starters: Bob Muncrief vs Buck Ross | Fifth | 6½ out |
| Friday, June 18 |
| » Lost to Indians (24-26), 5-3 | Comiskey Park I (10-10) | 21-24 | |
| » Starters: Al Smith vs Eddie Smith | Seventh | 6½ out |
| Saturday, June 19 |
| » Lost to Indians (25-26), 5-4 | Comiskey Park I (10-11) | 21-25 | Lost 2 |
| » Starters: Ray Poat vs Johnny Humphries | Seventh | 8 out |
| » Lost to Indians (26-26), 10-8 | Comiskey Park I (10-12) | 21-26 | Lost 3 |
| » Starters: Chubby Dean vs Thornton Lee | Seventh | 8 out |
| Sunday, June 20 |
| » Defeated Indians (26-27), 10-6 | Comiskey Park I (11-12) | 22-26 | |
| » Starters: Allie Reynolds vs Orval Grove | Seventh | 8 out |
| » Lost to Indians (27-27), 7-2 | Comiskey Park I (11-13) | 22-27 | |
| » Starters: Jim Bagby vs Bill Dietrich | Seventh | 8 out |
| Tuesday, June 22 |
| » Defeated Browns (22-28), 5-3 | Sportsman's Park III (2-2) | 23-27 | |
| » Starters: Johnny Humphries vs Bob Muncrief | Seventh | 7 out |
| Wednesday, June 23 |
| » Defeated Browns (22-29), 4-3 | Sportsman's Park III (3-2) | 24-27 | Won 2 |
| » Starters: Eddie Smith vs Steve Sundra | Sixth | 6½ out |
| Thursday, June 24 |
| » Lost to Browns (23-29), 8-7 | Sportsman's Park III (3-3) | 24-28 | |
| » Starters: Orval Grove vs Johnny Niggeling | Sixth | 6½ out |
| » Defeated Browns (23-30), 9-2 | Sportsman's Park III (4-3) | 25-28 | |
| » Starters: Buck Ross vs Al Hollingsworth | Sixth | 6½ out |
| Friday, June 25 |
| » Lost to Indians (29-29), 6-2 | Cleveland Stadium (0-1) | 25-29 | |
| » Starters: Jake Wade vs Al Smith | Seventh | 7 out |
| Saturday, June 26 |
| » Defeated Indians (29-30), 3-2 | Cleveland Stadium (1-1) | 26-29 | |
| » Starters: Thornton Lee vs Chubby Dean | Fifth | 6 out |
| Sunday, June 27 |
| » Lost to Indians (30-30), 2-1 | Cleveland Stadium (1-2) | 26-30 | |
| » Starters: Johnny Humphries vs Jack Salveson | Fifth | 6 out |
| » Defeated Indians (30-31), 2-0 | Cleveland Stadium (2-2) | 27-30 | |
| » Starters: Eddie Smith vs Vern Kennedy | Fifth | 6 out |
| Wednesday, June 30 |
| » Defeated Senators (34-29), 7-1 | Comiskey Park I (12-13) | 28-30 | Won 2 |
| » Starters: Dutch Leonard vs Orval Grove | Fifth | 6 out |
| Thursday, July 1 |
| » Defeated Senators (34-30), 2-0 | Comiskey Park I (13-13) | 29-30 | Won 3 |
| » Starters: Early Wynn vs Bill Dietrich | Fourth | 5 out |
| Friday, July 2 |
| » Lost to Senators (35-30), 3-2 | Comiskey Park I (13-14) | 29-31 | |
| » Starters: Milo Candini vs Johnny Humphries | Sixth | 5 out |
| Saturday, July 3 |
| » Defeated Athletics (30-38), 6-4 | Comiskey Park I (14-14) | 30-31 | |
| » Starters: Roger Wolff vs Buck Ross | Fifth | 3½ out |
| Sunday, July 4 |
| » Defeated Athletics (30-39), 5-2 | Comiskey Park I (15-14) | 31-31 | Won 2 |
| » Starters: Bert Kuczynski vs Thornton Lee | Third | 2½ out |
| » Defeated Athletics (30-40), 5-1 | Comiskey Park I (16-14) | 32-31 | Won 3 |
| » Starters: Russ Christopher vs Orval Grove | Third | 2½ out |
| Monday, July 5 |
| » Defeated Red Sox (33-34), 4-2 | Comiskey Park I (17-14) | 33-31 | Won 4 |
| » Starters: Tex Hughson vs Bill Dietrich | Third | 3½ out |
| » Lost to Red Sox (34-34), 6-1 | Comiskey Park I (17-15) | 33-32 | |
| » Starters: Yank Terry vs Eddie Smith | Third | 3½ out |
| Wednesday, July 7 |
| » Defeated Red Sox (34-35), 3-2 | Comiskey Park I (18-15) | 34-32 | |
| » Starters: Oscar Judd vs Johnny Humphries | Third | 4 out |
| Thursday, July 8 |
| » Defeated Yankees (39-30), 1-0 | Comiskey Park I (19-15) | 35-32 | Won 2 |
| » Starters: Hank Borowy vs Orval Grove | Third | 3 out |
| Friday, July 9 |
| Future White Sox Mike Andrews is born in Los Angeles, CA. |
| Saturday, July 10 |
| » Lost to Yankees (40-30), 9-2 | Comiskey Park I (19-16) | 35-33 | |
| » Starters: Tiny Bonham vs Bill Dietrich | Fourth | 5 out |
| » Lost to Yankees (41-30), 8-3 | Comiskey Park I (19-17) | 35-34 | Lost 2 |
| » Starters: Butch Wensloff vs Buck Ross | Fourth | 5 out |
| Sunday, July 11 |
| » Lost to Yankees (42-30), 9-0 | Comiskey Park I (19-18) | 35-35 | Lost 3 |
| » Starters: Spud Chandler vs Thornton Lee | Fourth | 7 out |
| » Lost to Yankees (43-30), 8-6 | Comiskey Park I (19-19) | 35-36 | Lost 4 |
| » Starters: Atley Donald vs Johnny Humphries | Fourth | 7 out |
| Thursday, July 15 |
| » Defeated Tigers (38-35), 7-4 | Comiskey Park I (20-19) | 36-36 | |
| » Starters: Dizzy Trout vs Orval Grove | Fourth | 6½ out |
| Saturday, July 17 |
| » Defeated Tigers (38-36), 5-2 | Comiskey Park I (21-19) | 37-36 | Won 2 |
| » Starters: Hal Newhouser vs Bill Dietrich | Fifth | 7½ out |
| » Lost to Tigers (39-36), 3-0 | Comiskey Park I (21-20) | 37-37 | |
| » Starters: Tommy Bridges vs Buck Ross | Fifth | 7½ out |
| Sunday, July 18 |
| » Lost to Tigers (40-36), 12-4 | Comiskey Park I (21-21) | 37-38 | Lost 2 |
| » Starters: Hal White vs Thornton Lee | Fourth | 8½ out |
| » Defeated Tigers (40-37), 4-1 | Comiskey Park I (22-21) | 38-38 | |
| » Starters: Dizzy Trout vs Johnny Humphries | Fourth | 8½ out |
| Wednesday, July 21 |
| » Lost to Red Sox (37-43), 3-2 | Fenway Park (3-3) | 38-39 | |
| » Starters: Bill Dietrich vs Tex Hughson | Fourth | 8 out |
| » Defeated Red Sox (37-44), 8-6 | Fenway Park (4-3) | 39-39 | |
| » Starters: Orval Grove vs Oscar Judd | Fourth | 8 out |
| Friday, July 23 |
| » Lost to Red Sox (38-44), 8-7 | Fenway Park (4-4) | 39-40 | |
| » Starters: Johnny Humphries vs Yank Terry | Fourth | 9 out |
| » Defeated Red Sox (38-45), 5-1 | Fenway Park (5-4) | 40-40 | |
| » Starters: Buck Ross vs Dick Newsome | Fourth | 9 out |
| Saturday, July 24 |
| » Lost to Yankees (50-31), 5-1 | Yankee Stadium (2-2) | 40-41 | |
| » Starters: Thornton Lee vs Spud Chandler | Fourth | 9 out |
| » Defeated Yankees (50-32), 5-3 | Yankee Stadium (3-2) | 41-41 | |
| » Starters: Eddie Smith vs Marius Russo | Fourth | 9 out |
| Sunday, July 25 |
| » Defeated Yankees (50-33), 2-1 | Yankee Stadium (4-2) | 42-41 | Won 2 |
| » Starters: Bill Dietrich vs Tiny Bonham | Fourth | 9 out |
| » Lost to Yankees (51-33), 6-3 | Yankee Stadium (4-3) | 42-42 | |
| » Starters: Orval Grove vs Butch Wensloff | Fourth | 9 out |
| Monday, July 26 |
| » Lost to Yankees (52-33), 5-2 | Yankee Stadium (4-4) | 42-43 | Lost 2 |
| » Starters: Jake Wade vs Bill Zuber | Fifth | 10 out |
| Tuesday, July 27 |
| » Defeated Senators (46-45), 6-5 | Griffith Stadium (3-1) | 43-43 | |
| » Starters: Johnny Humphries vs Dutch Leonard | Fourth | 10 out |
| Wednesday, July 28 |
| » Defeated Senators (46-46), 12-7 | Griffith Stadium (4-1) | 44-43 | Won 2 |
| » Starters: Buck Ross vs Ray Scarborough | Second | 9 out |
| Thursday, July 29 |
| » Defeated Senators (46-47), 5-4 | Griffith Stadium (5-1) | 45-43 | Won 3 |
| » Starters: Eddie Smith vs Mickey Haefner | Second | 9 out |
| Friday, July 30 |
| » Lost to Senators (47-47), 4-1 | Griffith Stadium (5-2) | 45-44 | |
| » Starters: Thornton Lee vs Early Wynn | Second | 10 out |
| Saturday, July 31 |
| » Defeated Athletics (38-55), 7-1 | Shibe Park (1-2) | 46-44 | |
| » Starters: Bill Dietrich vs Lum Harris | Second | 8½ out |
| » Defeated Athletics (38-56), 4-3 | Shibe Park (2-2) | 47-44 | Won 2 |
| » Starters: Orval Grove vs Jesse Flores | Second | 8½ out |
| » Major-league debuts: Vern Benson (Athletics) |
| Future White Sox Billy Wynne is born in Williamston, NC. |
| Sunday, August 1 |
| » Defeated Athletics (38-57), 5-1 | Shibe Park (3-2) | 48-44 | Won 3 |
| » Starters: Buck Ross vs Everett Fagan | Second | 8½ out |
| » Defeated Athletics (38-58), 15-9 | Shibe Park (4-2) | 49-44 | Won 4 |
| » Starters: Johnny Humphries vs Don Black | Second | 8½ out |
| Monday, August 2 |
| » Lost to Athletics (39-58), 5-3 | Shibe Park (4-3) | 49-45 | |
| » Starters: Eddie Smith vs Roger Wolff | Second | 9 out |
| Friday, August 6 |
| » Lost to Tigers (48-47), 6-0 | Tiger Stadium (2-4) | 49-46 | Lost 2 |
| » Starters: Orval Grove vs Dizzy Trout | Third | 9 out |
| Saturday, August 7 |
| » Defeated Tigers (48-48), 7-4 | Tiger Stadium (3-4) | 50-46 | |
| » Starters: Bill Dietrich vs Hal Newhouser | Third | 9 out |
| Sunday, August 8 |
| » Lost to Tigers (49-48), 8-2 | Tiger Stadium (3-5) | 50-47 | |
| » Starters: Thornton Lee vs Virgil Trucks | Third | 11 out |
| » Lost to Tigers (50-48), 3-0 | Tiger Stadium (3-6) | 50-48 | Lost 2 |
| » Starters: Buck Ross vs Tommy Bridges | Third | 11 out |
| Tuesday, August 10 |
| » Defeated Red Sox (48-52), 4-2 | Comiskey Park I (23-21) | 51-48 | |
| » Starters: Dick Newsome vs Eddie Smith | Third | 10 out |
| Wednesday, August 11 |
| » Lost to Red Sox (49-52), 10-0 | Comiskey Park I (23-22) | 51-49 | |
| » Starters: Joe Dobson vs Orval Grove | Fourth | 10 out |
| Thursday, August 12 |
| » Lost to Red Sox (50-52), 10-6 | Comiskey Park I (23-23) | 51-50 | Lost 2 |
| » Starters: Mike Ryba vs Bill Dietrich | Fourth | 10½ out |
| » Defeated Red Sox (50-53), 7-6 | Comiskey Park I (24-23) | 52-50 | |
| » Starters: Pinky Woods vs Buck Ross | Fourth | 10½ out |
| Friday, August 13 |
| » Defeated Red Sox (50-54), 3-2 | Comiskey Park I (25-23) | 53-50 | Won 2 |
| » Starters: Tex Hughson vs Johnny Humphries | Fourth | 10½ out |
| Saturday, August 14 |
| » Defeated Red Sox (50-55), 2-0 | Comiskey Park I (26-23) | 54-50 | Won 3 |
| » Starters: Yank Terry vs Thornton Lee | Fourth | 10½ out |
| Sunday, August 15 |
| » Lost to Yankees (65-39), 7-2 | Comiskey Park I (26-24) | 54-51 | |
| » Starters: Tiny Bonham vs Orval Grove | Fourth | 10½ out |
| » Defeated Yankees (65-40), 4-3 | Comiskey Park I (27-24) | 55-51 | |
| » Starters: Marius Russo vs Eddie Smith | Fourth | 10½ out |
| Monday, August 16 |
| » Lost to Yankees (66-40), 7-0 | Comiskey Park I (27-25) | 55-52 | |
| » Starters: Hank Borowy vs Bill Dietrich | Fifth | 11½ out |
| Tuesday, August 17 |
| » Lost to Yankees (67-40), 4-2 | Comiskey Park I (27-26) | 55-53 | Lost 2 |
| » Starters: Butch Wensloff vs Buck Ross | Fourth | 12½ out |
| Wednesday, August 18 |
| » Defeated Senators (59-53), 3-2 | Comiskey Park I (28-26) | 56-53 | |
| » Starters: Early Wynn vs Thornton Lee | Fifth | 11½ out |
| » Lost to Senators (60-53), 4-2 | Comiskey Park I (28-27) | 56-54 | |
| » Starters: Milo Candini vs Johnny Humphries | Fifth | 11½ out |
| Thursday, August 19 |
| » Lost to Senators (61-53), 4-3 | Comiskey Park I (28-28) | 56-55 | Lost 2 |
| » Starters: Dutch Leonard vs Orval Grove | Fourth | 12½ out |
| » Major-league debuts: Cass Michaels (White Sox) |
| Friday, August 20 |
| » Lost to Senators (62-53), 10-5 | Comiskey Park I (28-29) | 56-56 | Lost 3 |
| » Starters: Mickey Haefner vs Bill Dietrich | Fifth | 13½ out |
| Saturday, August 21 |
| » Defeated Senators (62-54), 5-4 | Comiskey Park I (29-29) | 57-56 | |
| » Starters: Bill LeFebvre vs Buck Ross | Fifth | 13½ out |
| Sunday, August 22 |
| » Defeated Athletics (40-74), 5-2 | Comiskey Park I (30-29) | 58-56 | Won 2 |
| » Starters: Jim Mains vs Eddie Smith | Fifth | 11½ out |
| » Defeated Athletics (40-75), 3-2 | Comiskey Park I (31-29) | 59-56 | Won 3 |
| » Starters: Jesse Flores vs Johnny Humphries | Fifth | 11½ out |
| Monday, August 23 |
| » Defeated Athletics (40-76), 7-6 | Comiskey Park I (32-29) | 60-56 | Won 4 |
| » Starters: Lou Ciola vs Thornton Lee | Fifth | 11 out |
| » Defeated Athletics (40-77), 7-0 | Comiskey Park I (33-29) | 61-56 | Won 5 |
| » Starters: Don Black vs Orval Grove | Fifth | 11 out |
| Tuesday, August 24 |
| » Defeated Athletics (40-78), 6-5 | Comiskey Park I (34-29) | 62-56 | Won 6 |
| » Starters: Lum Harris vs Buck Ross | Fifth | 11 out |
| » Lost to Athletics (41-78), 8-1 | Comiskey Park I (34-30) | 62-57 | |
| » Starters: Roger Wolff vs Bill Dietrich | Fifth | 11 out |
| Wednesday, August 25 |
| » Defeated Athletics (41-79), 4-0 | Comiskey Park I (35-30) | 63-57 | |
| » Starters: Orie Arntzen vs Jake Wade | Fourth | 11½ out |
| Friday, August 27 |
| » Lost to Indians (63-56), 6-2 | Comiskey Park I (35-31) | 63-58 | |
| » Starters: Al Smith vs Eddie Smith | Fourth | 12 out |
| Saturday, August 28 |
| » Defeated Indians (63-57), 7-6 | Comiskey Park I (36-31) | 64-58 | |
| » Starters: Jack Salveson vs Thornton Lee | Third | 11 out |
| Sunday, August 29 |
| » Lost to Indians (64-57), 2-1 | Comiskey Park I (36-32) | 64-59 | |
| » Starters: Mel Harder vs Orval Grove | Fifth | 13 out |
| » Lost to Indians (65-57), 6-1 | Comiskey Park I (36-33) | 64-60 | Lost 2 |
| » Starters: Allie Reynolds vs Johnny Humphries | Fifth | 13 out |
| Thursday, September 2 |
| » Lost to Indians (66-57), 2-1 | Cleveland Stadium (2-3) | 64-61 | Lost 3 |
| » Starters: Orval Grove vs Al Smith | Fifth | 14 out |
| Sunday, September 5 |
| » Defeated Indians (66-58), 2-1 | Cleveland Stadium (3-3) | 65-61 | |
| » Starters: Bill Dietrich vs Mel Harder | Fifth | 13 out |
| » Defeated Indians (66-59), 4-3 | Cleveland Stadium (4-3) | 66-61 | Won 2 |
| » Starters: Johnny Humphries vs Allie Reynolds | Fifth | 13 out |
| Tuesday, September 7 |
| » Lost to Tigers (67-60), 5-0 | Tiger Stadium (3-7) | 66-62 | |
| » Starters: Eddie Smith vs Dizzy Trout | Fifth | 14 out |
| » Lost to Tigers (68-60), 6-5 | Tiger Stadium (3-8) | 66-63 | Lost 2 |
| » Starters: Orval Grove vs Hal Newhouser | Fifth | 14 out |
| Friday, September 10 |
| » Lost to Browns (59-71), 6-2 | Sportsman's Park III (4-4) | 66-64 | Lost 3 |
| » Starters: Buck Ross vs Nels Potter | Fifth | 15½ out |
| Saturday, September 11 |
| » Lost to Browns (60-71), 4-1 | Sportsman's Park III (4-5) | 66-65 | Lost 4 |
| » Starters: Eddie Smith vs Al Hollingsworth | Fifth | 16½ out |
| Sunday, September 12 |
| » Lost to Browns (61-71), 2-0 | Sportsman's Park III (4-6) | 66-66 | Lost 5 |
| » Starters: Thornton Lee vs Bob Muncrief | Fifth | 18½ out |
| » Lost to Browns (62-71), 6-2 | Sportsman's Park III (4-7) | 66-67 | Lost 6 |
| » Starters: Orval Grove vs Denny Galehouse | Fifth | 18½ out |
| Tuesday, September 14 |
| » Defeated Tigers (69-66), 7-1 | Comiskey Park I (37-33) | 67-67 | |
| » Starters: Hal White vs Bill Dietrich | Fifth | 19 out |
| » Lost to Tigers (70-66), 7-5 | Comiskey Park I (37-34) | 67-68 | |
| » Starters: Virgil Trucks vs Johnny Humphries | Fifth | 19 out |
| Wednesday, September 15 |
| » Lost to Tigers (71-66), 8-2 | Comiskey Park I (37-35) | 67-69 | Lost 2 |
| » Starters: Rufe Gentry vs Eddie Smith | Fifth | 20 out |
| Friday, September 17 |
| » Defeated Browns (65-72), 2-1 | Comiskey Park I (38-35) | 68-69 | |
| » Starters: Denny Galehouse vs Orval Grove | Fifth | 19½ out |
| Saturday, September 18 |
| » Defeated Browns (65-73), 3-2 | Comiskey Park I (39-35) | 69-69 | Won 2 |
| » Starters: Bob Muncrief vs Bill Dietrich | Fifth | 19 out |
| Sunday, September 19 |
| » Lost to Browns (66-73), 7-4 | Comiskey Park I (39-36) | 69-70 | |
| » Starters: Steve Sundra vs Thornton Lee | Fifth | 18 out |
| » Defeated Browns (66-74), 6-1 | Comiskey Park I (40-36) | 70-70 | |
| » Starters: Nels Potter vs Johnny Humphries | Fifth | 18 out |
| Monday, September 20 |
| Future White Sox Rich Morales is born in San Francisco, CA. |
| Wednesday, September 22 |
| » Defeated Athletics (46-93), 6-0 | Shibe Park (5-3) | 71-70 | Won 2 |
| » Starters: Eddie Smith vs Don Black | Fourth | 17½ out |
| » Defeated Athletics (46-94), 2-1 | Shibe Park (6-3) | 72-70 | Won 3 |
| » Starters: Buck Ross vs Lum Harris | Fourth | 17½ out |
| Thursday, September 23 |
| » Defeated Athletics (46-95), 5-2 | Shibe Park (7-3) | 73-70 | Won 4 |
| » Starters: Orval Grove vs Roger Wolff | Fourth | 17½ out |
| Friday, September 24 |
| » Tied Athletics, 3-3 | Shibe Park (7-3) | 73-70 | |
| » Starters: Bill Dietrich vs Jesse Flores | Fourth | 17 out |
| Saturday, September 25 |
| » Defeated Athletics (46-96), 4-2 | Shibe Park (8-3) | 74-70 | Won 5 |
| » Starters: Joe Haynes vs Ted Abernathy | Fourth | 16½ out |
| » Defeated Athletics (46-97), 5-2 | Shibe Park (9-3) | 75-70 | Won 6 |
| » Starters: Jake Wade vs Russ Christopher | Fourth | 16½ out |
| Sunday, September 26 |
| » Defeated Senators (81-65), 15-3 | Griffith Stadium (6-2) | 76-70 | Won 7 |
| » Starters: Eddie Smith vs Early Wynn | Fourth | 17½ out |
| » Lost to Senators (82-65), 5-2 | Griffith Stadium (6-3) | 76-71 | |
| » Starters: Johnny Humphries vs Mickey Haefner | Fourth | 17½ out |
| Monday, September 27 |
| » Defeated Senators (82-66), 2-1 | Griffith Stadium (7-3) | 77-71 | |
| » Starters: Buck Ross vs Dutch Leonard | Fourth | 17 out |
| » Defeated Senators (82-67), 2-1 | Griffith Stadium (8-3) | 78-71 | Won 2 |
| » Starters: Orval Grove vs Bobo Newsom | Fourth | 17 out |
| Tuesday, September 28 |
| » Major-league debuts: Lew Flick (Athletics) |
| Wednesday, September 29 |
| » Defeated Yankees (94-55), 3-0 | Yankee Stadium (5-4) | 79-71 | Won 3 |
| » Starters: Bill Dietrich vs Marius Russo | Fourth | 16½ out |
| » Lost to Yankees (95-55), 4-0 | Yankee Stadium (5-5) | 79-72 | |
| » Starters: Jake Wade vs Butch Wensloff | Fourth | 16½ out |
| Thursday, September 30 |
| » Defeated Yankees (95-56), 8-3 | Yankee Stadium (6-5) | 80-72 | |
| » Starters: Eddie Smith vs Spud Chandler | Fourth | 15½ out |
| Sunday, October 3 |
| » Defeated Red Sox (68-83), 4-2 | Fenway Park (6-4) | 81-72 | Won 2 |
| » Starters: Bill Dietrich vs Lou Lucier | Fourth | 16 out |
| » Defeated Red Sox (68-84), 3-1 | Fenway Park (7-4) | 82-72 | Won 3 |
| » Starters: Orval Grove vs Emmett O'Neill | Fourth | 16 out |
| Wednesday, October 6 |
| Future White Sox Jim McGlothin is born in Los Angeles, CA. |
| Sunday, October 31 |
| Future White Sox Bill Voss is born in Glendale, CA. |
| Friday, November 19 |
| Future White Sox Aurelio Monteagudo is born in Caibarien, Cuba. |
| Monday, December 6 |
| Former White Sox George Magoon dies in Rochester, NH at the age of 69. |
| Sunday, December 19 |
| Future White Sox Walt Williams is born in Brownwood, TX. |
Game information provided by Retrosheet (www.retrosheet.org) |