| Tuesday, February 16 |
| Future Red Sox Bobby Darwin is born in Los Angeles, CA. |
| Sunday, February 21 |
| Future Red Sox Jack Billingham is born in Orlando, FL. Future Red Sox Joe Foy is born in New York, NY. |
| Saturday, March 20 |
| Former Red Sox Heinie Wagner dies in New Rochelle, NY at the age of 63. |
| Monday, April 12 |
| Future Red Sox Vincente Romo is born in Santa Rosalia, Mexico. |
| Wednesday, April 21 |
| » Major-league debuts: Lou Klein (Cardinals) |
| Thursday, April 22 |
| » Defeated Athletics (0-2), 1-0 | Shibe Park (1-0) | 1-0 | |
| » Starters: Tex Hughson vs Jesse Flores | First | -- |
| » Major-league debuts: Johnny Lazor (Red Sox) |
| Friday, April 23 |
| » Lost to Athletics (1-2), 5-0 | Shibe Park (1-1) | 1-1 | |
| » Starters: Joe Dobson vs Russ Christopher | Second | ½ out |
| » Major-league debuts: Tom McBride and Roy Partee (Red Sox) |
| Saturday, April 24 |
| » Lost to Athletics (2-2), 7-6 | Shibe Park (1-2) | 1-2 | Lost 2 |
| » Starters: Yank Terry vs Orie Arntzen | Fifth | 1½ out |
| » Major-league debuts: Andy Karl (Red Sox) |
| Sunday, April 25 |
| » Lost to Yankees (3-0), 7-1 | Yankee Stadium (0-1) | 1-3 | Lost 3 |
| » Starters: Ken Chase vs Hank Borowy | Seventh | 2½ out |
| Future Red Sox Lew Krausse is born in Media, PA. |
| Tuesday, April 27 |
| » Defeated Yankees (3-1), 5-1 | Fenway Park (1-0) | 2-3 | |
| » Starters: Marius Russo vs Tex Hughson | Sixth | 1½ out |
| » Major-league debuts: Tommy Byrne and Bud Metheny (Yankees) |
| Wednesday, April 28 |
| » Lost to Yankees (4-1), 5-0 | Fenway Park (1-1) | 2-4 | |
| » Starters: Tiny Bonham vs Joe Dobson | Seventh | 2½ out |
| Thursday, April 29 |
| » Lost to Yankees (5-1), 7-3 | Fenway Park (1-2) | 2-5 | Lost 2 |
| » Starters: Spud Chandler vs Yank Terry | Seventh | 3½ out |
| Saturday, May 1 |
| » Defeated Athletics (3-7), 3-1 | Fenway Park (2-2) | 3-5 | |
| » Starters: Lum Harris vs Oscar Judd | Fourth | 3 out |
| Sunday, May 2 |
| » Defeated Athletics (3-8), 7-6 | Fenway Park (3-2) | 4-5 | Won 2 |
| » Starters: Orie Arntzen vs Tex Hughson | Sixth | 3 out |
| » Lost to Athletics (4-8), 8-1 | Fenway Park (3-3) | 4-6 | |
| » Starters: Roger Wolff vs Ken Chase | Sixth | 3 out |
| Tuesday, May 4 |
| » Lost to Yankees (8-3), 4-3 | Yankee Stadium (0-2) | 4-7 | Lost 2 |
| » Starters: Joe Dobson vs Spud Chandler | Seventh | 4 out |
| Wednesday, May 5 |
| » Lost to Yankees (9-3), 4-3 | Yankee Stadium (0-3) | 4-8 | Lost 3 |
| » Starters: Tex Hughson vs Hank Borowy | Seventh | 5 out |
| Thursday, May 6 |
| » Lost to Yankees (10-3), 2-1 | Yankee Stadium (0-4) | 4-9 | Lost 4 |
| » Starters: Oscar Judd vs Tiny Bonham | Seventh | 7 out |
| » Lost to Yankees (11-3), 5-4 | Yankee Stadium (0-5) | 4-10 | Lost 5 |
| » Starters: Dick Newsome vs Tommy Byrne | Seventh | 7 out |
| » Major-league debuts: Aaron Robinson (Yankees) |
| Friday, May 7 |
| » Defeated Senators (8-8), 3-2 | Griffith Stadium (1-0) | 5-10 | |
| » Starters: Yank Terry vs Early Wynn | Seventh | 7 out |
| Saturday, May 8 |
| » Defeated Senators (8-9), 2-1 | Griffith Stadium (2-0) | 6-10 | Won 2 |
| » Starters: Joe Dobson vs Jim Mertz | Seventh | 6 out |
| Sunday, May 9 |
| » Lost to Senators (9-9), 3-2 | Griffith Stadium (2-1) | 6-11 | |
| » Starters: Tex Hughson vs Dutch Leonard | Eighth | 7 out |
| » Lost to Senators (10-9), 8-2 | Griffith Stadium (2-2) | 6-12 | Lost 2 |
| » Starters: Ken Chase vs Alex Carrasquel | Eighth | 7 out |
| Wednesday, May 12 |
| » Lost to Browns (8-7), 6-4 | Sportsman's Park III (0-1) | 6-13 | Lost 3 |
| » Starters: Joe Dobson vs Denny Galehouse | Eighth | 7 out |
| Thursday, May 13 |
| » Defeated Browns (8-8), 6-4 | Sportsman's Park III (1-1) | 7-13 | |
| » Starters: Tex Hughson vs Steve Sundra | Eighth | 6½ out |
| Sunday, May 16 |
| » Lost to White Sox (8-10), 4-2 | Comiskey Park I (0-1) | 7-14 | |
| » Starters: Dick Newsome vs Bill Dietrich | Eighth | 6 out |
| » Defeated White Sox (8-11), 4-2 | Comiskey Park I (1-1) | 8-14 | |
| » Starters: Lou Lucier vs Johnny Humphries | Eighth | 6 out |
| » Major-league debuts: Leon Culberson (Red Sox) |
| Thursday, May 20 |
| » Defeated Indians (13-10), 2-1 | League Park II (1-0) | 9-14 | Won 2 |
| » Starters: Oscar Judd vs Jack Salveson | Eighth | 5 out |
| » Defeated Indians (13-11), 7-4 | League Park II (2-0) | 10-14 | Won 3 |
| » Starters: Ken Chase vs Pete Center | Eighth | 5 out |
| Friday, May 21 |
| » Lost to Tigers (11-11), 2-1 | Tiger Stadium (0-1) | 10-15 | |
| » Starters: Tex Hughson vs Hal Newhouser | Eighth | 5½ out |
| Saturday, May 22 |
| » Lost to Tigers (12-11), 4-0 | Tiger Stadium (0-2) | 10-16 | Lost 2 |
| » Starters: Dick Newsome vs Dizzy Trout | Eighth | 5½ out |
| Sunday, May 23 |
| » Lost to Tigers (13-11), 4-3 | Tiger Stadium (0-3) | 10-17 | Lost 3 |
| » Starters: Joe Dobson vs Tommy Bridges | Seventh | 5½ out |
| » Defeated Tigers (13-12), 3-2 | Tiger Stadium (1-3) | 11-17 | |
| » Starters: Yank Terry vs Stubby Overmire | Seventh | 5½ out |
| Thursday, May 27 |
| » Defeated Indians (16-12), 2-0 | Fenway Park (4-3) | 12-17 | Won 2 |
| » Starters: Mike Naymick vs Tex Hughson | Sixth | 4 out |
| » Defeated Indians (16-13), 4-3 | Fenway Park (5-3) | 13-17 | Won 3 |
| » Starters: Jim Bagby vs Oscar Judd | Sixth | 4 out |
| Friday, May 28 |
| » Lost to Indians (17-13), 5-2 | Fenway Park (5-4) | 13-18 | |
| » Starters: Jack Salveson vs Ken Chase | Fifth | 4½ out |
| Saturday, May 29 |
| » Lost to Tigers (15-13), 6-4 | Fenway Park (5-5) | 13-19 | Lost 2 |
| » Starters: Tommy Bridges vs Yank Terry | Seventh | 5½ out |
| Sunday, May 30 |
| » Defeated Tigers (15-14), 3-0 | Fenway Park (6-5) | 14-19 | |
| » Starters: Virgil Trucks vs Dick Newsome | Seventh | 5 out |
| » Defeated Tigers (15-15), 5-1 | Fenway Park (7-5) | 15-19 | Won 2 |
| » Starters: Stubby Overmire vs Lou Lucier | Seventh | 5 out |
| Monday, May 31 |
| » Defeated Browns (11-17), 2-1 | Fenway Park (8-5) | 16-19 | Won 3 |
| » Starters: Johnny Niggeling vs Tex Hughson | Sixth | 4 out |
| » Defeated Browns (11-18), 7-6 | Fenway Park (9-5) | 17-19 | Won 4 |
| » Starters: Paul Dean vs Oscar Judd | Sixth | 4 out |
| Wednesday, June 2 |
| » Lost to Browns (12-18), 7-4 | Fenway Park (9-6) | 17-20 | |
| » Starters: Al Hollingsworth vs Joe Dobson | Sixth | 3½ out |
| » Defeated Browns (12-19), 3-2 | Fenway Park (10-6) | 18-20 | |
| » Starters: Fritz Ostermueller vs Yank Terry | Sixth | 3½ out |
| Thursday, June 3 |
| » Lost to White Sox (15-16), 6-4 | Fenway Park (10-7) | 18-21 | |
| » Starters: Joe Haynes vs Dick Newsome | Seventh | 4½ out |
| Friday, June 4 |
| » Lost to White Sox (16-16), 4-3 | Fenway Park (10-8) | 18-22 | Lost 2 |
| » Starters: Buck Ross vs Lou Lucier | Seventh | 5½ out |
| Saturday, June 5 |
| » Lost to White Sox (17-16), 4-1 | Fenway Park (10-9) | 18-23 | Lost 3 |
| » Starters: Thornton Lee vs Tex Hughson | Seventh | 5½ out |
| Sunday, June 6 |
| » Defeated White Sox (17-17), 4-3 | Fenway Park (11-9) | 19-23 | |
| » Starters: Orval Grove vs Oscar Judd | Seventh | 5½ out |
| » Defeated White Sox (17-18), 3-2 | Fenway Park (12-9) | 20-23 | Won 2 |
| » Starters: Jake Wade vs Yank Terry | Seventh | 5½ out |
| Wednesday, June 9 |
| » Defeated Senators (24-19), 3-2 | Fenway Park (13-9) | 21-23 | Won 3 |
| » Starters: Dutch Leonard vs Tex Hughson | Sixth | 5 out |
| Thursday, June 10 |
| » Defeated Senators (24-20), 2-0 | Fenway Park (14-9) | 22-23 | Won 4 |
| » Starters: Early Wynn vs Oscar Judd | Fifth | 5 out |
| Saturday, June 12 |
| » Lost to Senators (25-20), 1-0 | Fenway Park (14-10) | 22-24 | |
| » Starters: Milo Candini vs Yank Terry | Fifth | 6½ out |
| Sunday, June 13 |
| » Lost to Senators (26-20), 16-5 | Fenway Park (14-11) | 22-25 | Lost 2 |
| » Starters: Jim Mertz vs Lou Lucier | Fifth | 5½ out |
| » Defeated Senators (26-21), 7-0 | Fenway Park (15-11) | 23-25 | |
| » Starters: Alex Carrasquel vs Tex Hughson | Fifth | 5½ out |
| Tuesday, June 15 |
| » Lost to Athletics (25-24), 7-4 | Fenway Park (15-12) | 23-26 | |
| » Starters: Lum Harris vs Oscar Judd | Sixth | 7½ out |
| » Lost to Athletics (26-24), 4-2 | Fenway Park (15-13) | 23-27 | Lost 2 |
| » Starters: Jesse Flores vs Dick Newsome | Sixth | 7½ out |
| Wednesday, June 16 |
| » Defeated Athletics (26-25), 3-2 | Fenway Park (16-13) | 24-27 | |
| » Starters: Orie Arntzen vs Yank Terry | Fifth | 6½ out |
| Thursday, June 17 |
| » Defeated Athletics (26-26), 5-4 | Fenway Park (17-13) | 25-27 | Won 2 |
| » Starters: Russ Christopher vs Lou Lucier | Sixth | 7 out |
| » Lost to Athletics (27-26), 8-7 | Fenway Park (17-14) | 25-28 | |
| » Starters: Don Black vs Dick Newsome | Sixth | 7 out |
| Friday, June 18 |
| » Defeated Yankees (29-19), 3-1 | Yankee Stadium (1-5) | 26-28 | |
| » Starters: Tex Hughson vs Hank Borowy | Fifth | 6 out |
| Saturday, June 19 |
| » Lost to Yankees (30-19), 2-1 | Yankee Stadium (1-6) | 26-29 | |
| » Starters: Oscar Judd vs Spud Chandler | Sixth | 7 out |
| Sunday, June 20 |
| » Defeated Athletics (27-29), 7-3 | Shibe Park (2-2) | 27-29 | |
| » Starters: Yank Terry vs Roger Wolff | Fourth | 6 out |
| » Defeated Athletics (27-30), 6-5 | Shibe Park (3-2) | 28-29 | Won 2 |
| » Starters: Pinky Woods vs Jesse Flores | Fourth | 6 out |
| » Major-league debuts: Pinky Woods (Red Sox) |
| Tuesday, June 22 |
| » Defeated Athletics (27-31), 7-1 | Shibe Park (4-2) | 29-29 | Won 3 |
| » Starters: Tex Hughson vs Russ Christopher | Fourth | 5 out |
| Wednesday, June 23 |
| » Defeated Athletics (27-32), 1-0 | Shibe Park (5-2) | 30-29 | Won 4 |
| » Starters: Oscar Judd vs Don Black | Third | 4½ out |
| Thursday, June 24 |
| » Lost to Athletics (28-32), 8-3 | Shibe Park (5-3) | 30-30 | |
| » Starters: Dick Newsome vs Lum Harris | Third | 5 out |
| Friday, June 25 |
| » Tied Yankees, 2-2 | Fenway Park (17-14) | 30-30 | |
| » Starters: Butch Wensloff vs Yank Terry | Fourth | 5 out |
| Saturday, June 26 |
| » Defeated Yankees (32-23), 4-1 | Fenway Park (18-14) | 31-30 | |
| » Starters: Atley Donald vs Tex Hughson | Third | 4 out |
| Sunday, June 27 |
| » Lost to Yankees (33-23), 3-2 | Fenway Park (18-15) | 31-31 | |
| » Starters: Spud Chandler vs Oscar Judd | Third | 4 out |
| » Defeated Yankees (33-24), 4-3 | Fenway Park (19-15) | 32-31 | |
| » Starters: Tiny Bonham vs Lou Lucier | Third | 4 out |
| Future Red Sox Rico Petrocelli is born in Brooklyn, NY. |
| Wednesday, June 30 |
| » Tied Tigers, 3-3 | Tiger Stadium (1-3) | 32-31 | |
| » Starters: Tex Hughson vs Virgil Trucks | Third | 4½ out |
| Thursday, July 1 |
| » Lost to Tigers (28-30), 3-2 | Tiger Stadium (1-4) | 32-32 | |
| » Starters: Oscar Judd vs Dizzy Trout | Third | 4½ out |
| Friday, July 2 |
| » Lost to Tigers (29-30), 8-2 | Tiger Stadium (1-5) | 32-33 | Lost 2 |
| » Starters: Yank Terry vs Tommy Bridges | Fifth | 4½ out |
| Saturday, July 3 |
| » Defeated Indians (32-33), 12-4 | Cleveland Stadium (1-0) | 33-33 | |
| » Starters: Joe Dobson vs Chubby Dean | Fourth | 3 out |
| Monday, July 5 |
| » Lost to White Sox (33-31), 4-2 | Comiskey Park I (1-2) | 33-34 | |
| » Starters: Tex Hughson vs Bill Dietrich | Fourth | 4 out |
| » Defeated White Sox (33-32), 6-1 | Comiskey Park I (2-2) | 34-34 | |
| » Starters: Yank Terry vs Eddie Smith | Fourth | 4 out |
| Wednesday, July 7 |
| » Lost to White Sox (34-32), 3-2 | Comiskey Park I (2-3) | 34-35 | |
| » Starters: Oscar Judd vs Johnny Humphries | Fifth | 5½ out |
| Thursday, July 8 |
| » Lost to Browns (32-36), 5-2 | Sportsman's Park III (1-2) | 34-36 | Lost 2 |
| » Starters: Joe Dobson vs Steve Sundra | Sixth | 5½ out |
| Friday, July 9 |
| » Lost to Browns (33-36), 5-4 | Sportsman's Park III (1-3) | 34-37 | Lost 3 |
| » Starters: Tex Hughson vs Bob Muncrief | Sixth | 6 out |
| Future Red Sox Mike Andrews is born in Los Angeles, CA. |
| Saturday, July 10 |
| » Defeated Browns (33-37), 6-3 | Sportsman's Park III (2-3) | 35-37 | |
| » Starters: Yank Terry vs Denny Galehouse | Fifth | 6½ out |
| Sunday, July 11 |
| » Lost to Browns (34-37), 8-7 | Sportsman's Park III (2-4) | 35-38 | |
| » Starters: Oscar Judd vs Johnny Niggeling | Seventh | 8½ out |
| » Lost to Browns (35-37), 4-2 | Sportsman's Park III (2-5) | 35-39 | Lost 2 |
| » Starters: Pinky Woods vs Nels Potter | Seventh | 8½ out |
| Thursday, July 15 |
| » Lost to Senators (41-37), 4-3 | Griffith Stadium (2-3) | 35-40 | Lost 3 |
| » Starters: Yank Terry vs Early Wynn | Seventh | 9 out |
| Friday, July 16 |
| » Defeated Senators (41-38), 4-1 | Griffith Stadium (3-3) | 36-40 | |
| » Starters: Oscar Judd vs Milo Candini | Sixth | 9 out |
| » Major-league debuts: Catfish Metkovich (Red Sox) |
| Saturday, July 17 |
| » Lost to Senators (42-38), 3-0 | Griffith Stadium (3-4) | 36-41 | |
| » Starters: Tex Hughson vs Dutch Leonard | Sixth | 10 out |
| Sunday, July 18 |
| » Lost to Senators (43-38), 9-2 | Griffith Stadium (3-5) | 36-42 | Lost 2 |
| » Starters: Dick Newsome vs Ray Scarborough | Seventh | 12 out |
| » Lost to Senators (44-38), 5-4 | Griffith Stadium (3-6) | 36-43 | Lost 3 |
| » Starters: Lou Lucier vs Early Wynn | Seventh | 12 out |
| Wednesday, July 21 |
| » Defeated White Sox (38-39), 3-2 | Fenway Park (20-15) | 37-43 | |
| » Starters: Bill Dietrich vs Tex Hughson | Sixth | 11½ out |
| » Lost to White Sox (39-39), 8-6 | Fenway Park (20-16) | 37-44 | |
| » Starters: Orval Grove vs Oscar Judd | Sixth | 11½ out |
| Friday, July 23 |
| » Defeated White Sox (39-40), 8-7 | Fenway Park (21-16) | 38-44 | |
| » Starters: Johnny Humphries vs Yank Terry | Seventh | 12½ out |
| » Lost to White Sox (40-40), 5-1 | Fenway Park (21-17) | 38-45 | |
| » Starters: Buck Ross vs Dick Newsome | Seventh | 12½ out |
| Saturday, July 24 |
| » Defeated Browns (39-42), 5-3 | Fenway Park (22-17) | 39-45 | |
| » Starters: Bobo Newsom vs Oscar Judd | Sixth | 12 out |
| Sunday, July 25 |
| » Defeated Browns (39-43), 7-0 | Fenway Park (23-17) | 40-45 | Won 2 |
| » Starters: Steve Sundra vs Tex Hughson | Fifth | 11 out |
| » Defeated Browns (39-44), 6-4 | Fenway Park (24-17) | 41-45 | Won 3 |
| » Starters: Johnny Niggeling vs Mike Ryba | Fifth | 11 out |
| Monday, July 26 |
| » Lost to Browns (40-44), 7-1 | Fenway Park (24-18) | 41-46 | |
| » Starters: Bob Muncrief vs Yank Terry | Seventh | 12 out |
| Wednesday, July 28 |
| » Defeated Tigers (44-42), 4-1 | Fenway Park (25-18) | 42-46 | |
| » Starters: Virgil Trucks vs Oscar Judd | Fifth | 11 out |
| » Defeated Tigers (44-43), 6-4 | Fenway Park (26-18) | 43-46 | Won 2 |
| » Starters: Hal White vs Dick Newsome | Fifth | 11 out |
| Friday, July 30 |
| » Defeated Tigers (44-44), 4-2 | Fenway Park (27-18) | 44-46 | Won 3 |
| » Starters: Dizzy Trout vs Tex Hughson | Fifth | 12 out |
| » Lost to Tigers (45-44), 5-2 | Fenway Park (27-19) | 44-47 | |
| » Starters: Johnny Gorsica vs Pinky Woods | Fifth | 12 out |
| Saturday, July 31 |
| » Defeated Indians (44-46), 5-4 | Fenway Park (28-19) | 45-47 | |
| » Starters: Allie Reynolds vs Mike Ryba | Sixth | 11 out |
| Sunday, August 1 |
| » Lost to Indians (45-46), 8-6 | Fenway Park (28-20) | 45-48 | |
| » Starters: Al Smith vs Oscar Judd | Sixth | 12 out |
| » Defeated Indians (45-47), 4-1 | Fenway Park (29-20) | 46-48 | |
| » Starters: Mel Harder vs Dick Newsome | Sixth | 12 out |
| Monday, August 2 |
| Future Red Sox Tom Burgmeier is born in St. Paul, MN. |
| Tuesday, August 3 |
| » Lost to Indians (46-47), 11-9 | Fenway Park (29-21) | 46-49 | |
| » Starters: Jim Bagby vs Yank Terry | Sixth | 12½ out |
| » Major-league debuts: Emmett O'Neill (Red Sox) |
| Friday, August 6 |
| » Lost to Senators (54-47), 4-2 | Fenway Park (29-22) | 46-50 | Lost 2 |
| » Starters: Dutch Leonard vs Dick Newsome | Sixth | 12½ out |
| Saturday, August 7 |
| » Defeated Senators (54-48), 7-5 | Fenway Park (30-22) | 47-50 | |
| » Starters: Jim Mertz vs Joe Dobson | Sixth | 12½ out |
| » Major-league debuts: Ox Miller (Senators) |
| Sunday, August 8 |
| » Lost to Senators (55-48), 4-3 | Fenway Park (30-23) | 47-51 | |
| » Starters: Early Wynn vs Mike Ryba | Fifth | 13½ out |
| » Defeated Senators (55-49), 4-3 | Fenway Park (31-23) | 48-51 | |
| » Starters: Milo Candini vs Pinky Woods | Fifth | 13½ out |
| Tuesday, August 10 |
| » Lost to White Sox (51-48), 4-2 | Comiskey Park I (2-4) | 48-52 | |
| » Starters: Dick Newsome vs Eddie Smith | Sixth | 13½ out |
| Wednesday, August 11 |
| » Defeated White Sox (51-49), 10-0 | Comiskey Park I (3-4) | 49-52 | |
| » Starters: Joe Dobson vs Orval Grove | Fifth | 12½ out |
| Thursday, August 12 |
| » Defeated White Sox (51-50), 10-6 | Comiskey Park I (4-4) | 50-52 | Won 2 |
| » Starters: Mike Ryba vs Bill Dietrich | Fifth | 13 out |
| » Lost to White Sox (52-50), 7-6 | Comiskey Park I (4-5) | 50-53 | |
| » Starters: Pinky Woods vs Buck Ross | Fifth | 13 out |
| Friday, August 13 |
| » Lost to White Sox (53-50), 3-2 | Comiskey Park I (4-6) | 50-54 | Lost 2 |
| » Starters: Tex Hughson vs Johnny Humphries | Sixth | 14 out |
| Saturday, August 14 |
| » Lost to White Sox (54-50), 2-0 | Comiskey Park I (4-7) | 50-55 | Lost 3 |
| » Starters: Yank Terry vs Thornton Lee | Sixth | 15 out |
| Sunday, August 15 |
| » Defeated Browns (45-58), 3-2 | Sportsman's Park III (3-5) | 51-55 | |
| » Starters: Oscar Judd vs Denny Galehouse | Sixth | 14 out |
| » Defeated Browns (45-59), 4-0 | Sportsman's Park III (4-5) | 52-55 | Won 2 |
| » Starters: Joe Dobson vs Steve Sundra | Sixth | 14 out |
| Monday, August 16 |
| » Defeated Browns (45-60), 9-0 | Sportsman's Park III (5-5) | 53-55 | Won 3 |
| » Starters: Mike Ryba vs Bobo Newsom | Sixth | 14 out |
| Tuesday, August 17 |
| » Lost to Browns (46-60), 4-1 | Sportsman's Park III (5-6) | 53-56 | |
| » Starters: Tex Hughson vs Johnny Niggeling | Fifth | 15 out |
| Wednesday, August 18 |
| » Lost to Tigers (56-50), 1-0 | Tiger Stadium (1-6) | 53-57 | Lost 2 |
| » Starters: Yank Terry vs Hal White | Sixth | 14½ out |
| Thursday, August 19 |
| » Defeated Tigers (56-51), 4-3 | Tiger Stadium (2-6) | 54-57 | |
| » Starters: Dick Newsome vs Hal Newhouser | Fifth | 15 out |
| » Lost to Tigers (57-51), 10-0 | Tiger Stadium (2-7) | 54-58 | |
| » Starters: Pinky Woods vs Virgil Trucks | Fifth | 15 out |
| Friday, August 20 |
| » Lost to Tigers (58-51), 1-0 | Tiger Stadium (2-8) | 54-59 | Lost 2 |
| » Starters: Joe Dobson vs Stubby Overmire | Sixth | 16 out |
| Saturday, August 21 |
| » Defeated Tigers (58-52), 7-6 | Tiger Stadium (3-8) | 55-59 | |
| » Starters: Tex Hughson vs Johnny Gorsica | Sixth | 16 out |
| Sunday, August 22 |
| » Lost to Indians (58-53), 6-0 | Cleveland Stadium (1-1) | 55-60 | |
| » Starters: Mike Ryba vs Jack Salveson | Sixth | 16 out |
| » Lost to Indians (59-53), 7-6 | Cleveland Stadium (1-2) | 55-61 | Lost 2 |
| » Starters: Yank Terry vs Mike Naymick | Sixth | 16 out |
| Monday, August 23 |
| » Defeated Indians (59-54), 9-7 | League Park II (3-0) | 56-61 | |
| » Starters: Pinky Woods vs Al Smith | Sixth | 16 out |
| Tuesday, August 24 |
| » Lost to Indians (60-54), 5-2 | Cleveland Stadium (1-3) | 56-62 | |
| » Starters: Emmett O'Neill vs Allie Reynolds | Sixth | 16 out |
| » Defeated Indians (60-55), 7-0 | Cleveland Stadium (2-3) | 57-62 | |
| » Starters: Dick Newsome vs Mel Harder | Sixth | 16 out |
| Wednesday, August 25 |
| » Lost to Indians (61-55), 8-3 | League Park II (3-1) | 57-63 | |
| » Starters: Joe Dobson vs Vern Kennedy | Sixth | 18 out |
| » Lost to Indians (62-55), 4-1 | League Park II (3-2) | 57-64 | Lost 2 |
| » Starters: Tex Hughson vs Ray Poat | Sixth | 18 out |
| Thursday, August 26 |
| » Defeated Indians (62-56), 4-1 | League Park II (4-2) | 58-64 | |
| » Starters: Mike Ryba vs Mike Naymick | Sixth | 17½ out |
| Saturday, August 28 |
| » Defeated Yankees (74-46), 2-1 | Yankee Stadium (2-6) | 59-64 | Won 2 |
| » Starters: Dick Newsome vs Bill Zuber | Sixth | 16½ out |
| Sunday, August 29 |
| » Lost to Yankees (75-46), 6-4 | Yankee Stadium (2-7) | 59-65 | |
| » Starters: Tex Hughson vs Tiny Bonham | Sixth | 18½ out |
| » Lost to Yankees (76-46), 5-1 | Yankee Stadium (2-8) | 59-66 | Lost 2 |
| » Starters: Joe Dobson vs Spud Chandler | Sixth | 18½ out |
| Monday, August 30 |
| » Lost to Yankees (77-46), 3-1 | Yankee Stadium (2-9) | 59-67 | Lost 3 |
| » Starters: Pinky Woods vs Butch Wensloff | Sixth | 19½ out |
| Future Red Sox Carmen Fanzone is born in Detroit, MI. |
| Friday, September 3 |
| » Lost to Athletics (42-82), 5-4 | Fenway Park (31-24) | 59-68 | Lost 4 |
| » Starters: Orie Arntzen vs Mike Ryba | Sixth | 20½ out |
| Saturday, September 4 |
| » Defeated Athletics (42-83), 2-1 | Fenway Park (32-24) | 60-68 | |
| » Starters: Lum Harris vs Dick Newsome | Sixth | 20½ out |
| Sunday, September 5 |
| » Lost to Athletics (43-83), 7-5 | Fenway Park (32-25) | 60-69 | |
| » Starters: Jesse Flores vs Pinky Woods | Sixth | 20 out |
| Monday, September 6 |
| » Defeated Senators (71-61), 5-1 | Fenway Park (33-25) | 61-69 | |
| » Starters: Milo Candini vs Tex Hughson | Sixth | 19 out |
| » Defeated Senators (71-62), 4-1 | Fenway Park (34-25) | 62-69 | Won 2 |
| » Starters: Jim Mertz vs Joe Dobson | Sixth | 19 out |
| Tuesday, September 7 |
| Future Red Sox Tommy Matchick is born in Hazleton, PA. |
| Thursday, September 9 |
| » Lost to Yankees (81-49), 11-3 | Fenway Park (34-26) | 62-70 | |
| » Starters: Hank Borowy vs Dick Newsome | Sixth | 20 out |
| Friday, September 10 |
| » Lost to Yankees (82-49), 9-3 | Fenway Park (34-27) | 62-71 | Lost 2 |
| » Starters: Marius Russo vs Tex Hughson | Sixth | 21 out |
| Saturday, September 11 |
| » Lost to Yankees (83-49), 4-0 | Fenway Park (34-28) | 62-72 | Lost 3 |
| » Starters: Spud Chandler vs Emmett O'Neill | Sixth | 22 out |
| Sunday, September 12 |
| » Lost to Yankees (84-49), 1-0 | Fenway Park (34-29) | 62-73 | Lost 4 |
| » Starters: Tiny Bonham vs Joe Dobson | Seventh | 24 out |
| » Lost to Yankees (85-49), 9-6 | Fenway Park (34-30) | 62-74 | Lost 5 |
| » Starters: Butch Wensloff vs Pinky Woods | Seventh | 24 out |
| Tuesday, September 14 |
| » Lost to Senators (76-62), 3-2 | Griffith Stadium (3-7) | 62-75 | Lost 6 |
| » Starters: Dick Newsome vs Milo Candini | Seventh | 25 out |
| » Major-league debuts: Danny Doyle (Red Sox) |
| Wednesday, September 15 |
| » Lost to Senators (77-62), 5-0 | Griffith Stadium (3-8) | 62-76 | Lost 7 |
| » Starters: Tex Hughson vs Johnny Niggeling | Seventh | 26 out |
| Saturday, September 18 |
| » Lost to Athletics (45-91), 5-4 | Shibe Park (5-4) | 62-77 | Lost 8 |
| » Starters: Emmett O'Neill vs Don Black | Seventh | 26½ out |
| Sunday, September 19 |
| » Defeated Athletics (45-92), 14-0 | Shibe Park (6-4) | 63-77 | |
| » Starters: Joe Dobson vs Roger Wolff | Seventh | 25½ out |
| » Lost to Athletics (46-92), 6-1 | Shibe Park (6-5) | 63-78 | |
| » Starters: Pinky Woods vs Jesse Flores | Seventh | 25½ out |
| Thursday, September 23 |
| » Defeated Indians (76-65), 13-7 | Fenway Park (35-30) | 64-78 | |
| » Starters: Mel Harder vs Dick Newsome | Seventh | 26½ out |
| » Lost to Indians (77-65), 6-4 | Fenway Park (35-31) | 64-79 | |
| » Starters: Allie Reynolds vs Tex Hughson | Seventh | 26½ out |
| » Major-league debuts: Gene Woodling (Indians) |
| Friday, September 24 |
| » Defeated Indians (77-66), 1-0 | Fenway Park (36-31) | 65-79 | |
| » Starters: Ed Klieman vs Joe Dobson | Seventh | 25½ out |
| Saturday, September 25 |
| » Lost to Indians (78-66), 6-3 | Fenway Park (36-32) | 65-80 | |
| » Starters: Jim Bagby vs Emmett O'Neill | Seventh | 26½ out |
| Sunday, September 26 |
| » Defeated Tigers (73-73), 3-2 | Fenway Park (37-32) | 66-80 | |
| » Starters: Hal White vs Lou Lucier | Seventh | 26½ out |
| » Defeated Tigers (73-74), 6-2 | Fenway Park (38-32) | 67-80 | Won 2 |
| » Starters: Tommy Bridges vs Yank Terry | Seventh | 26½ out |
| Monday, September 27 |
| » Lost to Tigers (74-74), 6-3 | Fenway Park (38-33) | 67-81 | |
| » Starters: Virgil Trucks vs Dick Newsome | Seventh | 27½ out |
| Tuesday, September 28 |
| » Defeated Tigers (74-75), 6-1 | Fenway Park (39-33) | 68-81 | |
| » Starters: Hal Newhouser vs Pinky Woods | Seventh | 26½ out |
| Wednesday, September 29 |
| » Lost to Browns (72-77), 4-3 | Fenway Park (39-34) | 68-82 | |
| » Starters: Nels Potter vs Tex Hughson | Seventh | 27 out |
| » Tied Browns, 3-3 | Fenway Park (39-34) | 68-82 | |
| » Starters: Denny Galehouse vs Joe Dobson | Seventh | 27 out |
| Sunday, October 3 |
| » Lost to White Sox (81-72), 4-2 | Fenway Park (39-35) | 68-83 | Lost 2 |
| » Starters: Bill Dietrich vs Lou Lucier | Seventh | 29 out |
| » Lost to White Sox (82-72), 3-1 | Fenway Park (39-36) | 68-84 | Lost 3 |
| » Starters: Orval Grove vs Emmett O'Neill | Seventh | 29 out |
| Wednesday, October 6 |
| Future Red Sox Jerry Stephenson is born in Detroit, MI. |
| Monday, December 6 |
| Former Red Sox Charley Hall dies in Ventura, CA at the age of 59. |
| Friday, December 10 |
| Future Red Sox Dalton Jones is born in McComb, MS. |
| Tuesday, December 21 |
| Former Red Sox Jack Warner dies in Far Rockaway, NY at the age of 72. |
Game information provided by Retrosheet (www.retrosheet.org) |