| Monday, February 16 |
| Future White Sox Tim Cullen is born in San Francisco, CA. |
| Sunday, March 8 |
| Future White Sox Dick Allen is born in Wampum, PA. |
| Friday, March 13 |
| Future White Sox Marv Staehle is born in Oak Park, IL. |
| Thursday, March 26 |
| Former White Sox Jimmy Burke dies in St.Louis, MO at the age of 68. |
| Sunday, April 12 |
| Future White Sox Tommy Sisk is born in Ardmore, OK. |
| Tuesday, April 14 |
| » Lost to Browns (1-0), 3-0 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Bob Muncrief vs Johnny Rigney | Second | 1 out |
| » Major-league debuts: Thurman Tucker (White Sox) |
| Wednesday, April 15 |
| » Lost to Browns (2-0), 6-5 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » Starters: Elden Auker vs Johnny Humphries | Third | 2 out |
| » Major-league debuts: Tony Criscola (Browns) |
| Thursday, April 16 |
| » Lost to Browns (3-0), 13-3 | Comiskey Park I (0-3) | 0-3 | Lost 3 |
| » Starters: Denny Galehouse vs Bill Dietrich | Fourth | 3 out |
| Friday, April 17 |
| » Defeated Indians (1-3), 1-0 | Cleveland Stadium (1-0) | 1-3 | |
| » Starters: Ted Lyons vs Mel Harder | Fourth | 3 out |
| Saturday, April 18 |
| » Lost to Indians (2-3), 1-0 | Cleveland Stadium (1-1) | 1-4 | |
| » Starters: Eddie Smith vs Jim Bagby | Fourth | 3 out |
| Monday, April 20 |
| » Defeated Tigers (4-4), 3-1 | Comiskey Park I (1-3) | 2-4 | |
| » Starters: Dizzy Trout vs Johnny Rigney | Seventh | 2½ out |
| Tuesday, April 21 |
| » Lost to Tigers (5-4), 4-2 | Comiskey Park I (1-4) | 2-5 | |
| » Starters: Schoolboy Rowe vs Johnny Humphries | Fifth | 3 out |
| Wednesday, April 22 |
| » Defeated Tigers (5-5), 3-1 | Comiskey Park I (2-4) | 3-5 | |
| » Starters: Tommy Bridges vs Bill Dietrich | Fourth | 3 out |
| Thursday, April 23 |
| » Lost to Tigers (6-5), 9-0 | Tiger Stadium (0-1) | 3-6 | |
| » Starters: Ted Lyons vs Hal White | Sixth | 4 out |
| Friday, April 24 |
| » Lost to Tigers (7-5), 2-1 | Tiger Stadium (0-2) | 3-7 | Lost 2 |
| » Starters: Eddie Smith vs Al Benton | Seventh | 5 out |
| Saturday, April 25 |
| » Lost to Indians (8-3), 5-4 | Comiskey Park I (2-5) | 3-8 | Lost 3 |
| » Starters: Al Milnar vs Johnny Humphries | Sixth | 5 out |
| Sunday, April 26 |
| » Lost to Indians (9-3), 3-2 | Comiskey Park I (2-6) | 3-9 | Lost 4 |
| » Starters: Al Smith vs Johnny Rigney | Sixth | 6 out |
| Tuesday, April 28 |
| » Lost to Senators (6-9), 4-3 | Griffith Stadium (0-1) | 3-10 | Lost 5 |
| » Starters: Eddie Smith vs Bobo Newsom | Eighth | 7 out |
| Wednesday, April 29 |
| » Lost to Senators (7-9), 10-4 | Griffith Stadium (0-2) | 3-11 | Lost 6 |
| » Starters: Bill Dietrich vs Sid Hudson | Eighth | 8 out |
| Thursday, April 30 |
| » Lost to Senators (8-9), 1-0 | Griffith Stadium (0-3) | 3-12 | Lost 7 |
| » Starters: Ted Lyons vs Early Wynn | Eighth | 9 out |
| Friday, May 1 |
| » Defeated Athletics (5-13), 5-2 | Shibe Park (1-0) | 4-12 | |
| » Starters: Johnny Rigney vs Lum Harris | Eighth | 9 out |
| Saturday, May 2 |
| » Lost to Athletics (6-13), 7-6 | Shibe Park (1-1) | 4-13 | |
| » Starters: Buck Ross vs Roger Wolff | Seventh | 10 out |
| Sunday, May 3 |
| » Lost to Yankees (11-7), 6-4 | Yankee Stadium (0-1) | 4-14 | Lost 2 |
| » Starters: Eddie Smith vs Red Ruffing | Eighth | 10½ out |
| » Lost to Yankees (12-7), 3-1 | Yankee Stadium (0-2) | 4-15 | Lost 3 |
| » Starters: Bill Dietrich vs Atley Donald | Eighth | 10½ out |
| Monday, May 4 |
| » Lost to Yankees (13-7), 6-1 | Yankee Stadium (0-3) | 4-16 | Lost 4 |
| » Starters: Johnny Humphries vs Spud Chandler | Eighth | 10½ out |
| Tuesday, May 5 |
| » Lost to Yankees (14-7), 5-4 | Yankee Stadium (0-4) | 4-17 | Lost 5 |
| » Starters: Johnny Rigney vs Johnny Lindell | Eighth | 10½ out |
| Wednesday, May 6 |
| » Lost to Red Sox (14-7), 3-1 | Fenway Park (0-1) | 4-18 | Lost 6 |
| » Starters: Ted Lyons vs Joe Dobson | Seventh | 11 out |
| Saturday, May 9 |
| » Defeated Browns (10-15), 2-1 | Sportsman's Park III (1-0) | 5-18 | |
| » Starters: Bill Dietrich vs Johnny Niggeling | Seventh | 10½ out |
| Sunday, May 10 |
| » Lost to Browns (11-15), 5-2 | Sportsman's Park III (1-1) | 5-19 | |
| » Starters: Eddie Smith vs Elden Auker | Seventh | 11½ out |
| » Defeated Browns (11-16), 9-7 | Sportsman's Park III (2-1) | 6-19 | |
| » Starters: Johnny Rigney vs Denny Galehouse | Seventh | 11½ out |
| Wednesday, May 13 |
| » Defeated Red Sox (14-11), 2-1 | Comiskey Park I (3-6) | 7-19 | Won 2 |
| » Starters: Charlie Wagner vs Johnny Humphries | Eighth | 10½ out |
| Thursday, May 14 |
| » Defeated Athletics (13-17), 9-4 | Comiskey Park I (4-6) | 8-19 | Won 3 |
| » Starters: Jack Knott vs Bill Dietrich | Eighth | 10 out |
| Saturday, May 16 |
| » Defeated Athletics (13-18), 4-3 | Comiskey Park I (5-6) | 9-19 | Won 4 |
| » Starters: Phil Marchildon vs Eddie Smith | Eighth | 10½ out |
| Sunday, May 17 |
| » Defeated Senators (12-17), 7-1 | Comiskey Park I (6-6) | 10-19 | Won 5 |
| » Starters: Bobo Newsom vs Ted Lyons | Seventh | 9½ out |
| » Defeated Senators (12-18), 4-3 | Comiskey Park I (7-6) | 11-19 | Won 6 |
| » Starters: Steve Sundra vs Johnny Rigney | Seventh | 9½ out |
| Monday, May 18 |
| » Defeated Senators (12-19), 7-5 | Comiskey Park I (8-6) | 12-19 | Won 7 |
| » Starters: Hardin Cathey vs Orval Grove | Sixth | 9 out |
| Wednesday, May 20 |
| » Lost to Yankees (21-9), 4-1 | Comiskey Park I (8-7) | 12-20 | |
| » Starters: Marius Russo vs Bill Dietrich | Seventh | 10 out |
| Former White Sox Amby McConnell dies in Utica, NY at the age of 60. |
| Thursday, May 21 |
| » Lost to Yankees (22-9), 1-0 | Comiskey Park I (8-8) | 12-21 | Lost 2 |
| » Starters: Tiny Bonham vs Eddie Smith | Eighth | 11 out |
| Friday, May 22 |
| » Defeated Tigers (20-18), 7-4 | Comiskey Park I (9-8) | 13-21 | |
| » Starters: Virgil Trucks vs Johnny Humphries | Eighth | 10½ out |
| Sunday, May 24 |
| » Lost to Tigers (21-18), 6-2 | Comiskey Park I (9-9) | 13-22 | |
| » Starters: Tommy Bridges vs Ted Lyons | Eighth | 11½ out |
| » Lost to Tigers (22-18), 14-0 | Comiskey Park I (9-10) | 13-23 | Lost 2 |
| » Starters: Hal White vs Orval Grove | Eighth | 11½ out |
| Monday, May 25 |
| » Defeated Indians (22-15), 5-1 | League Park II (1-0) | 14-23 | |
| » Starters: Bill Dietrich vs Chubby Dean | Eighth | 11½ out |
| Former White Sox Bill James dies in Venice, CA at the age of 56. |
| Tuesday, May 26 |
| » Lost to Indians (23-15), 2-1 | Cleveland Stadium (1-2) | 14-24 | |
| » Starters: Eddie Smith vs Mel Harder | Eighth | 12½ out |
| Wednesday, May 27 |
| » Defeated Indians (23-16), 9-7 | League Park II (2-0) | 15-24 | |
| » Starters: Johnny Humphries vs Jim Bagby | Eighth | 12½ out |
| Thursday, May 28 |
| » Lost to Browns (20-22), 6-4 | Sportsman's Park III (2-2) | 15-25 | |
| » Starters: Orval Grove vs Elden Auker | Eighth | 13½ out |
| Future White Sox Buddy Booker is born in Lynchburg, VA. |
| Friday, May 29 |
| » Defeated Browns (20-23), 12-8 | Sportsman's Park III (3-2) | 16-25 | |
| » Starters: Bill Dietrich vs Denny Galehouse | Seventh | 13½ out |
| Saturday, May 30 |
| » Lost to Tigers (26-20), 9-4 | Tiger Stadium (0-3) | 16-26 | |
| » Starters: Eddie Smith vs Tommy Bridges | Seventh | 14½ out |
| » Defeated Tigers (26-21), 12-5 | Tiger Stadium (1-3) | 17-26 | |
| » Starters: Buck Ross vs Hal Newhouser | Seventh | 14½ out |
| Sunday, May 31 |
| » Defeated Tigers (26-22), 9-4 | Tiger Stadium (2-3) | 18-26 | Won 2 |
| » Starters: Ted Lyons vs Al Benton | Sixth | 14 out |
| Wednesday, June 3 |
| » Lost to Yankees (32-11), 4-1 | Yankee Stadium (0-5) | 18-27 | |
| » Starters: Bill Dietrich vs Tiny Bonham | Sixth | 15 out |
| Thursday, June 4 |
| » Lost to Yankees (33-11), 8-2 | Yankee Stadium (0-6) | 18-28 | Lost 2 |
| » Starters: Eddie Smith vs Hank Borowy | Sixth | 16 out |
| Friday, June 5 |
| » Lost to Red Sox (24-22), 4-2 | Fenway Park (0-2) | 18-29 | Lost 3 |
| » Starters: Johnny Humphries vs Yank Terry | Seventh | 17 out |
| Saturday, June 6 |
| » Defeated Red Sox (24-23), 3-1 | Fenway Park (1-2) | 19-29 | |
| » Starters: Orval Grove vs Tex Hughson | Seventh | 17 out |
| Sunday, June 7 |
| » Lost to Red Sox (25-23), 3-2 | Fenway Park (1-3) | 19-30 | |
| » Starters: Ted Lyons vs Dick Newsome | Seventh | 18 out |
| » Lost to Red Sox (26-23), 3-2 | Fenway Park (1-4) | 19-31 | Lost 2 |
| » Starters: Bill Dietrich vs Charlie Wagner | Seventh | 18 out |
| Tuesday, June 9 |
| » Lost to Athletics (22-35), 2-0 | Shibe Park (1-2) | 19-32 | Lost 3 |
| » Starters: Eddie Smith vs Bob Harris | Eighth | 19½ out |
| Wednesday, June 10 |
| » Defeated Athletics (22-36), 4-1 | Shibe Park (2-2) | 20-32 | |
| » Starters: Johnny Humphries vs Jack Knott | Seventh | 18½ out |
| Saturday, June 13 |
| » Lost to Senators (22-34), 4-3 | Griffith Stadium (0-4) | 20-33 | |
| » Starters: Bill Dietrich vs Alex Carrasquel | Eighth | 19½ out |
| Sunday, June 14 |
| » Defeated Senators (22-35), 9-3 | Griffith Stadium (1-4) | 21-33 | |
| » Starters: Ted Lyons vs Sid Hudson | Seventh | 19½ out |
| » Defeated Senators (22-36), 11-4 | Griffith Stadium (2-4) | 22-33 | Won 2 |
| » Starters: Eddie Smith vs Walt Masterson | Seventh | 19½ out |
| Monday, June 15 |
| Future White Sox Bruce Dal Canton is born in California, PA. |
| Tuesday, June 16 |
| » Defeated Athletics (25-38), 2-1 | Comiskey Park I (10-10) | 23-33 | Won 3 |
| » Starters: Bob Harris vs Orval Grove | Sixth | 19 out |
| Wednesday, June 17 |
| » Lost to Athletics (26-38), 4-3 | Comiskey Park I (10-11) | 23-34 | |
| » Starters: Phil Marchildon vs Johnny Humphries | Seventh | 19 out |
| Thursday, June 18 |
| » Defeated Athletics (26-39), 7-2 | Comiskey Park I (11-11) | 24-34 | |
| » Starters: Jack Knott vs Buck Ross | Sixth | 18 out |
| Friday, June 19 |
| » Lost to Red Sox (34-24), 1-0 | Comiskey Park I (11-12) | 24-35 | |
| » Starters: Charlie Wagner vs Eddie Smith | Sixth | 18 out |
| Sunday, June 21 |
| » Defeated Red Sox (34-25), 6-5 | Comiskey Park I (12-12) | 25-35 | |
| » Starters: Dick Newsome vs Ted Lyons | Sixth | 17½ out |
| » Lost to Red Sox (35-25), 7-0 | Comiskey Park I (12-13) | 25-36 | |
| » Starters: Tex Hughson vs Orval Grove | Sixth | 17½ out |
| Wednesday, June 24 |
| » Defeated Senators (24-41), 6-0 | Comiskey Park I (13-13) | 26-36 | |
| » Starters: Early Wynn vs Johnny Humphries | Sixth | 18 out |
| Thursday, June 25 |
| » Defeated Senators (24-42), 2-0 | Comiskey Park I (14-13) | 27-36 | Won 2 |
| » Starters: Sid Hudson vs Buck Ross | Sixth | 17½ out |
| Friday, June 26 |
| » Defeated Yankees (45-20), 4-2 | Comiskey Park I (15-13) | 28-36 | Won 3 |
| » Starters: Lefty Gomez vs Eddie Smith | Sixth | 16½ out |
| Saturday, June 27 |
| » Lost to Yankees (46-20), 7-3 | Comiskey Park I (15-14) | 28-37 | |
| » Starters: Spud Chandler vs Orval Grove | Sixth | 17½ out |
| Sunday, June 28 |
| » Defeated Yankees (46-21), 6-2 | Comiskey Park I (16-14) | 29-37 | |
| » Starters: Red Ruffing vs Ted Lyons | Sixth | 15½ out |
| » Defeated Yankees (46-22), 13-1 | Comiskey Park I (17-14) | 30-37 | Won 2 |
| » Starters: Tiny Bonham vs Johnny Humphries | Sixth | 15½ out |
| Monday, June 29 |
| » Lost to Indians (40-33), 11-5 | Comiskey Park I (17-15) | 30-38 | |
| » Starters: Al Milnar vs Buck Ross | Sixth | 16 out |
| Tuesday, June 30 |
| » Lost to Indians (41-33), 3-1 | Comiskey Park I (17-16) | 30-39 | Lost 2 |
| » Starters: Jim Bagby vs Eddie Smith | Sixth | 16½ out |
| Wednesday, July 1 |
| » Lost to Indians (42-33), 7-2 | Comiskey Park I (17-17) | 30-40 | Lost 3 |
| » Starters: Al Smith vs Orval Grove | Sixth | 16½ out |
| Thursday, July 2 |
| » Lost to Indians (43-33), 7-5 | Comiskey Park I (17-18) | 30-41 | Lost 4 |
| » Starters: Chubby Dean vs Johnny Humphries | Sixth | 17 out |
| Saturday, July 4 |
| » Lost to Browns (35-40), 8-5 | Comiskey Park I (17-19) | 30-42 | Lost 5 |
| » Starters: Denny Galehouse vs Eddie Smith | Sixth | 18½ out |
| » Lost to Browns (36-40), 8-7 | Comiskey Park I (17-20) | 30-43 | Lost 6 |
| » Starters: Al Hollingsworth vs Bill Dietrich | Sixth | 18½ out |
| Sunday, July 5 |
| » Defeated Browns (36-41), 14-2 | Comiskey Park I (18-20) | 31-43 | |
| » Starters: Elden Auker vs Ted Lyons | Sixth | 18½ out |
| » Lost to Browns (37-41), 13-2 | Comiskey Park I (18-21) | 31-44 | |
| » Starters: Steve Sundra vs Buck Ross | Sixth | 18½ out |
| Thursday, July 9 |
| » Defeated Senators (29-51), 4-2 | Griffith Stadium (3-4) | 32-44 | |
| » Starters: Johnny Humphries vs Walt Masterson | Sixth | 18½ out |
| Saturday, July 11 |
| » Defeated Senators (29-52), 5-3 | Griffith Stadium (4-4) | 33-44 | Won 2 |
| » Starters: Bill Dietrich vs Early Wynn | Sixth | 18 out |
| Sunday, July 12 |
| » Lost to Athletics (35-53), 3-2 | Shibe Park (2-3) | 33-45 | |
| » Starters: Eddie Smith vs Roger Wolff | Sixth | 18 out |
| » Defeated Athletics (35-54), 11-1 | Shibe Park (3-3) | 34-45 | |
| » Starters: Jake Wade vs Lum Harris | Sixth | 18 out |
| Monday, July 13 |
| » Lost to Athletics (36-54), 4-3 | Shibe Park (3-4) | 34-46 | |
| » Starters: Johnny Humphries vs Phil Marchildon | Sixth | 19 out |
| Wednesday, July 15 |
| » Lost to Red Sox (49-33), 10-1 | Fenway Park (1-5) | 34-47 | Lost 2 |
| » Starters: Eddie Smith vs Tex Hughson | Sixth | 20 out |
| » Defeated Red Sox (49-34), 11-6 | Fenway Park (2-5) | 35-47 | |
| » Starters: Bill Dietrich vs Charlie Wagner | Sixth | 20 out |
| Thursday, July 16 |
| » Defeated Red Sox (49-35), 3-2 | Fenway Park (3-5) | 36-47 | Won 2 |
| » Starters: Buck Ross vs Dick Newsome | Sixth | 20 out |
| Friday, July 17 |
| » Lost to Red Sox (50-35), 2-1 | Fenway Park (3-6) | 36-48 | |
| » Starters: Johnny Humphries vs Charlie Wagner | Sixth | 21 out |
| Future White Sox Don Kessinger is born in Forrest City, AR. |
| Saturday, July 18 |
| » Lost to Yankees (59-28), 7-6 | Yankee Stadium (0-7) | 36-49 | Lost 2 |
| » Starters: Jake Wade vs Marv Breuer | Sixth | 22 out |
| Sunday, July 19 |
| » Lost to Yankees (60-28), 9-2 | Yankee Stadium (0-8) | 36-50 | Lost 3 |
| » Starters: Bill Dietrich vs Hank Borowy | Sixth | 24 out |
| » Lost to Yankees (61-28), 12-0 | Yankee Stadium (0-9) | 36-51 | Lost 4 |
| » Starters: Eddie Smith vs Red Ruffing | Sixth | 24 out |
| Tuesday, July 21 |
| » Defeated Red Sox (50-38), 5-4 | Comiskey Park I (19-21) | 37-51 | |
| » Starters: Dick Newsome vs Johnny Humphries | Sixth | 24 out |
| Wednesday, July 22 |
| » Defeated Red Sox (50-39), 2-0 | Comiskey Park I (20-21) | 38-51 | Won 2 |
| » Starters: Charlie Wagner vs Buck Ross | Sixth | 24 out |
| Thursday, July 23 |
| » Lost to Red Sox (51-39), 5-4 | Comiskey Park I (20-22) | 38-52 | |
| » Starters: Tex Hughson vs Bill Dietrich | Sixth | 24 out |
| Friday, July 24 |
| » Defeated Athletics (38-62), 2-1 | Comiskey Park I (21-22) | 39-52 | |
| » Starters: Dick Fowler vs Jake Wade | Sixth | 24 out |
| Future White Sox Cotton Nash is born in Jersey City, NJ. |
| Saturday, July 25 |
| » Lost to Athletics (39-62), 2-1 | Comiskey Park I (21-23) | 39-53 | |
| » Starters: Phil Marchildon vs Thornton Lee | Sixth | 25 out |
| Sunday, July 26 |
| » Defeated Athletics (39-63), 2-1 | Comiskey Park I (22-23) | 40-53 | |
| » Starters: Roger Wolff vs Ted Lyons | Sixth | 25½ out |
| » Lost to Athletics (40-63), 3-2 | Comiskey Park I (22-24) | 40-54 | |
| » Starters: Lum Harris vs Johnny Humphries | Sixth | 25½ out |
| Tuesday, July 28 |
| » Lost to Yankees (67-29), 8-3 | Comiskey Park I (22-25) | 40-55 | Lost 2 |
| » Starters: Tiny Bonham vs Eddie Smith | Sixth | 26½ out |
| Wednesday, July 29 |
| » Defeated Yankees (67-30), 6-5 | Comiskey Park I (23-25) | 41-55 | |
| » Starters: Atley Donald vs Buck Ross | Sixth | 24½ out |
| » Defeated Yankees (67-31), 7-5 | Comiskey Park I (24-25) | 42-55 | Won 2 |
| » Starters: Lefty Gomez vs Jake Wade | Sixth | 24½ out |
| Friday, July 31 |
| » Defeated Senators (41-61), 7-2 | Comiskey Park I (25-25) | 43-55 | Won 3 |
| » Starters: Early Wynn vs Johnny Humphries | Sixth | 24 out |
| Tuesday, August 4 |
| » Defeated Tigers (51-56), 5-4 | Comiskey Park I (26-25) | 44-55 | Won 4 |
| » Starters: Tommy Bridges vs Ted Lyons | Sixth | 23½ out |
| Future White Sox Angel Bravo is born in Maracaibo, Venezuela. Future White Sox Cleon Jones is born in Plateau, AL. |
| Wednesday, August 5 |
| » Defeated Tigers (51-57), 1-0 | Comiskey Park I (27-25) | 45-55 | Won 5 |
| » Starters: Hal Newhouser vs Thornton Lee | Sixth | 23 out |
| Thursday, August 6 |
| » Defeated Tigers (51-58), 4-1 | Comiskey Park I (28-25) | 46-55 | Won 6 |
| » Starters: Al Benton vs Eddie Smith | Sixth | 22 out |
| Sunday, August 9 |
| » Defeated Indians (60-48), 11-1 | Comiskey Park I (29-25) | 47-55 | Won 7 |
| » Starters: Mel Harder vs Ted Lyons | Sixth | 21½ out |
| » Defeated Indians (60-49), 3-2 | Comiskey Park I (30-25) | 48-55 | Won 8 |
| » Starters: Jim Bagby vs Bill Dietrich | Sixth | 21½ out |
| Future White Sox Tommie Agee is born in Magnolia, AL. |
| Monday, August 10 |
| » Defeated Indians (60-50), 3-1 | Comiskey Park I (31-25) | 49-55 | Won 9 |
| » Starters: Chubby Dean vs Johnny Humphries | Fifth | 21 out |
| Tuesday, August 11 |
| » Lost to Browns (57-56), 9-2 | Sportsman's Park III (3-3) | 49-56 | |
| » Starters: Eddie Smith vs Denny Galehouse | Sixth | 21 out |
| Wednesday, August 12 |
| » Lost to Browns (58-56), 6-3 | Sportsman's Park III (3-4) | 49-57 | Lost 2 |
| » Starters: Jake Wade vs Elden Auker | Sixth | 22 out |
| Thursday, August 13 |
| » Lost to Browns (59-56), 8-3 | Sportsman's Park III (3-5) | 49-58 | Lost 3 |
| » Starters: Bill Dietrich vs Steve Sundra | Sixth | 22½ out |
| Friday, August 14 |
| » Lost to Tigers (57-61), 7-1 | Tiger Stadium (2-4) | 49-59 | Lost 4 |
| » Starters: Thornton Lee vs Hal White | Sixth | 23½ out |
| Saturday, August 15 |
| » Defeated Tigers (57-62), 4-2 | Tiger Stadium (3-4) | 50-59 | |
| » Starters: Johnny Humphries vs Al Benton | Sixth | 23 out |
| Sunday, August 16 |
| » Lost to Tigers (58-62), 3-2 | Tiger Stadium (3-5) | 50-60 | |
| » Starters: Ted Lyons vs Hal Newhouser | Sixth | 24½ out |
| » Lost to Tigers (59-62), 7-3 | Tiger Stadium (3-6) | 50-61 | Lost 2 |
| » Starters: Eddie Smith vs Dizzy Trout | Sixth | 24½ out |
| » Major-league debuts: Johnny Lipon (Tigers) |
| Tuesday, August 18 |
| » Lost to Browns (62-57), 7-0 | Comiskey Park I (31-26) | 50-62 | Lost 3 |
| » Starters: Denny Galehouse vs Jake Wade | Sixth | 25 out |
| Thursday, August 20 |
| » Defeated Browns (62-58), 8-5 | Comiskey Park I (32-26) | 51-62 | |
| » Starters: Steve Sundra vs Johnny Humphries | Sixth | 24 out |
| Friday, August 21 |
| » Lost to Indians (63-56), 3-2 | Cleveland Stadium (1-3) | 51-63 | |
| » Starters: Thornton Lee vs Mel Harder | Sixth | 25 out |
| Saturday, August 22 |
| » Defeated Indians (63-57), 3-1 | Cleveland Stadium (2-3) | 52-63 | |
| » Starters: Eddie Smith vs Chubby Dean | Sixth | 25 out |
| Sunday, August 23 |
| » Defeated Indians (63-58), 3-1 | Cleveland Stadium (3-3) | 53-63 | Won 2 |
| » Starters: Ted Lyons vs Al Smith | Sixth | 25 out |
| » Lost to Indians (64-58), 1-0 | Cleveland Stadium (3-4) | 53-64 | |
| » Starters: Jake Wade vs Jim Bagby | Sixth | 25 out |
| Future White Sox Danny Murphy is born in Beverly, MA. |
| Tuesday, August 25 |
| » Lost to Yankees (82-42), 5-3 | Yankee Stadium (0-10) | 53-65 | Lost 2 |
| » Starters: Johnny Humphries vs Marv Breuer | Sixth | 26 out |
| Wednesday, August 26 |
| » Defeated Yankees (82-43), 5-3 | Yankee Stadium (1-10) | 54-65 | |
| » Starters: Bill Dietrich vs Hank Borowy | Sixth | 25 out |
| Friday, August 28 |
| » Lost to Red Sox (76-52), 4-0 | Fenway Park (3-7) | 54-66 | |
| » Starters: Buck Ross vs Joe Dobson | Sixth | 26 out |
| Saturday, August 29 |
| » Lost to Red Sox (77-52), 4-2 | Fenway Park (3-8) | 54-67 | Lost 2 |
| » Starters: Jake Wade vs Charlie Wagner | Sixth | 26 out |
| » Major-league debuts: Bill Mueller (White Sox) |
| Sunday, August 30 |
| » Defeated Athletics (48-86), 2-1 | Shibe Park (4-4) | 55-67 | |
| » Starters: Ted Lyons vs Roger Wolff | Sixth | 27 out |
| » Lost to Athletics (49-86), 3-2 | Shibe Park (4-5) | 55-68 | |
| » Starters: Thornton Lee vs Phil Marchildon | Sixth | 27 out |
| Monday, August 31 |
| » Defeated Athletics (49-87), 3-1 | Shibe Park (5-5) | 56-68 | |
| » Starters: Johnny Humphries vs Russ Christopher | Sixth | 26½ out |
| » Defeated Athletics (49-88), 5-0 | Shibe Park (6-5) | 57-68 | Won 2 |
| » Starters: Eddie Smith vs Lum Harris | Sixth | 26½ out |
| Wednesday, September 2 |
| » Defeated Senators (51-76), 8-2 | Griffith Stadium (5-4) | 58-68 | Won 3 |
| » Starters: Buck Ross vs Early Wynn | Sixth | 26½ out |
| » Defeated Senators (51-77), 7-6 | Griffith Stadium (6-4) | 59-68 | Won 4 |
| » Starters: Jake Wade vs Lou Bevil | Sixth | 26½ out |
| Thursday, September 3 |
| » Lost to Senators (52-77), 3-2 | Griffith Stadium (6-5) | 59-69 | |
| » Starters: Bill Dietrich vs Sid Hudson | Sixth | 27½ out |
| » Lost to Senators (53-77), 14-0 | Griffith Stadium (6-6) | 59-70 | Lost 2 |
| » Starters: Thornton Lee vs Ray Scarborough | Sixth | 27½ out |
| Saturday, September 5 |
| » Lost to Tigers (65-71), 4-2 | Comiskey Park I (32-27) | 59-71 | Lost 3 |
| » Starters: Dizzy Trout vs Johnny Humphries | Sixth | 28 out |
| Sunday, September 6 |
| » Lost to Tigers (66-71), 2-0 | Comiskey Park I (32-28) | 59-72 | Lost 4 |
| » Starters: Tommy Bridges vs Buck Ross | Sixth | 29½ out |
| Tuesday, September 8 |
| » Lost to Indians (70-69), 10-0 | Comiskey Park I (32-29) | 59-73 | Lost 5 |
| » Starters: Ray Poat vs Thornton Lee | Sixth | 31 out |
| Wednesday, September 9 |
| » Major-league debuts: Eddie Robinson and Ted Sepkowski (Indians) |
| Thursday, September 10 |
| » Defeated Senators (55-82), 7-1 | Comiskey Park I (33-29) | 60-73 | |
| » Starters: Dutch Leonard vs Ted Lyons | Sixth | 31 out |
| » Lost to Senators (56-82), 5-4 | Comiskey Park I (33-30) | 60-74 | |
| » Starters: Bill Zuber vs Johnny Humphries | Sixth | 31 out |
| Friday, September 11 |
| » Defeated Yankees (94-47), 1-0 | Comiskey Park I (34-30) | 61-74 | |
| » Starters: Atley Donald vs Eddie Smith | Sixth | 30 out |
| Saturday, September 12 |
| » Lost to Yankees (95-47), 7-1 | Comiskey Park I (34-31) | 61-75 | |
| » Starters: Spud Chandler vs Jake Wade | Sixth | 31 out |
| Sunday, September 13 |
| » Lost to Red Sox (87-56), 6-1 | Comiskey Park I (34-32) | 61-76 | Lost 2 |
| » Starters: Bill Butland vs Buck Ross | Sixth | 33 out |
| » Lost to Red Sox (88-56), 5-0 | Comiskey Park I (34-33) | 61-77 | Lost 3 |
| » Starters: Tex Hughson vs Bill Dietrich | Sixth | 33 out |
| Monday, September 14 |
| » Defeated Red Sox (88-57), 4-0 | Comiskey Park I (35-33) | 62-77 | |
| » Starters: Dick Newsome vs Johnny Humphries | Sixth | 33 out |
| Wednesday, September 16 |
| » Lost to Athletics (53-96), 4-2 | Comiskey Park I (35-34) | 62-78 | |
| » Starters: Bob Harris vs Eddie Smith | Sixth | 34 out |
| Thursday, September 17 |
| » Lost to Athletics (54-96), 1-0 | Comiskey Park I (35-35) | 62-79 | Lost 2 |
| » Starters: Roger Wolff vs Len Perme | Sixth | 35 out |
| Saturday, September 19 |
| » Major-league debuts: Joe Coleman (Athletics) |
| Sunday, September 20 |
| » Defeated Browns (81-69), 6-5 | Sportsman's Park III (4-5) | 63-79 | |
| » Starters: Johnny Humphries vs Elden Auker | Sixth | 34½ out |
| » Lost to Browns (82-69), 4-2 | Sportsman's Park III (4-6) | 63-80 | |
| » Starters: Buck Ross vs Bob Muncrief | Sixth | 34½ out |
| Monday, September 21 |
| » Lost to Tigers (72-79), 6-4 | Tiger Stadium (3-7) | 63-81 | Lost 2 |
| » Starters: Joe Haynes vs Tommy Bridges | Sixth | 34½ out |
| Tuesday, September 22 |
| » Lost to Tigers (73-79), 9-2 | Tiger Stadium (3-8) | 63-82 | Lost 3 |
| » Starters: Bill Dietrich vs Dizzy Trout | Sixth | 35½ out |
| Thursday, September 24 |
| » Defeated Indians (73-77), 3-1 | League Park II (3-0) | 64-82 | |
| » Starters: Ted Lyons vs Al Smith | Sixth | 35 out |
| » Defeated Indians (73-78), 4-2 | League Park II (4-0) | 65-82 | Won 2 |
| » Starters: Eddie Smith vs Ray Poat | Sixth | 35 out |
| » Major-league debuts: Paul Calvert (Indians) |
| Friday, September 25 |
| » Defeated Indians (73-79), 8-1 | League Park II (5-0) | 66-82 | Won 3 |
| » Starters: Thornton Lee vs Chubby Dean | Fifth | 34½ out |
| Thursday, October 22 |
| Future White Sox Cecil Upshaw is born in Spearsville, LA. |
| Monday, November 2 |
| Future White Sox Ron Reed is born in LaPorte, IN. |
| Monday, November 23 |
| Future White Sox Jerry Nyman is born in Logan, UT. |
| Tuesday, November 24 |
| Former White Sox Frank Owen dies in Dearborn, MI at the age of 63. |
| Thursday, December 3 |
| Former White Sox Chad Kimsey dies in Pryor, OK at the age of 37. |
| Wednesday, December 23 |
| Future White Sox Jerry Koosman is born in Appleton, MN. |
Game information provided by Retrosheet (www.retrosheet.org) |
