| Tuesday, April 14 |
| » Defeated Athletics (0-1), 8-3 | Fenway Park (1-0) | 1-0 | |
| » Starters: Phil Marchildon vs Dick Newsome | First | -- |
| » Major-league debuts: Johnny Pesky (Red Sox) |
| Wednesday, April 15 |
| » Defeated Athletics (0-2), 3-1 | Fenway Park (2-0) | 2-0 | Won 2 |
| » Starters: Roger Wolff vs Joe Dobson | First | -- |
| Thursday, April 16 |
| » Defeated Athletics (0-3), 19-4 | Fenway Park (3-0) | 3-0 | Won 3 |
| » Starters: Fred Caligiuri vs Charlie Wagner | First | -- |
| Future Red Sox Jim Lonborg is born in Santa Maria, CA. |
| Friday, April 17 |
| » Lost to Yankees (4-0), 1-0 | Yankee Stadium (0-1) | 3-1 | |
| » Starters: Oscar Judd vs Tiny Bonham | Second | 1 out |
| Saturday, April 18 |
| » Defeated Yankees (4-1), 5-1 | Yankee Stadium (1-1) | 4-1 | |
| » Starters: Yank Terry vs Atley Donald | First | -- |
| » Major-league debuts: Hank Borowy and Mel Queen (Yankees) |
| Sunday, April 19 |
| » Defeated Yankees (4-2), 5-2 | Yankee Stadium (2-1) | 5-1 | Won 2 |
| » Starters: Dick Newsome vs Marv Breuer | First | -- |
| Monday, April 20 |
| » Lost to Senators (3-5), 10-4 | Fenway Park (3-1) | 5-2 | |
| » Starters: Jack Wilson vs Joe Dobson | First | -- |
| Wednesday, April 22 |
| » Defeated Senators (3-6), 13-4 | Griffith Stadium (1-0) | 6-2 | |
| » Starters: Oscar Judd vs Early Wynn | First | -- |
| Thursday, April 23 |
| » Lost to Senators (4-6), 10-5 | Griffith Stadium (1-1) | 6-3 | |
| » Starters: Yank Terry vs Dutch Leonard | Second | 1 out |
| Friday, April 24 |
| » Lost to Yankees (8-2), 8-5 | Fenway Park (3-2) | 6-4 | Lost 2 |
| » Starters: Tiny Bonham vs Dick Newsome | Third | 2 out |
| Saturday, April 25 |
| » Defeated Yankees (8-3), 4-2 | Fenway Park (4-2) | 7-4 | |
| » Starters: Lefty Gomez vs Joe Dobson | Second | 1 out |
| Sunday, April 26 |
| » Lost to Yankees (9-3), 7-2 | Fenway Park (4-3) | 7-5 | |
| » Starters: Marv Breuer vs Oscar Judd | Third | 2 out |
| Tuesday, April 28 |
| » Defeated Tigers (10-6), 6-1 | Fenway Park (5-3) | 8-5 | |
| » Starters: Hal White vs Charlie Wagner | Fourth | 2 out |
| Wednesday, April 29 |
| » Lost to Tigers (11-6), 4-2 | Fenway Park (5-4) | 8-6 | |
| » Starters: Al Benton vs Yank Terry | Fourth | 3 out |
| Thursday, April 30 |
| » Defeated Tigers (11-7), 8-3 | Fenway Park (6-4) | 9-6 | |
| » Starters: Charlie Fuchs vs Dick Newsome | Fourth | 3 out |
| Friday, May 1 |
| » Lost to Browns (8-11), 10-6 | Fenway Park (6-5) | 9-7 | |
| » Starters: Johnny Niggeling vs Joe Dobson | Fourth | 4 out |
| Saturday, May 2 |
| » Defeated Browns (8-12), 11-10 | Fenway Park (7-5) | 10-7 | |
| » Starters: Elden Auker vs Oscar Judd | Third | 4 out |
| Sunday, May 3 |
| » Defeated Indians (14-4), 8-4 | Fenway Park (8-5) | 11-7 | Won 2 |
| » Starters: Al Smith vs Charlie Wagner | Fourth | 3 out |
| Monday, May 4 |
| » Defeated Indians (14-5), 11-8 | Fenway Park (9-5) | 12-7 | Won 3 |
| » Starters: Al Milnar vs Dick Newsome | Fourth | 2 out |
| Tuesday, May 5 |
| » Defeated Indians (14-6), 13-3 | Fenway Park (10-5) | 13-7 | Won 4 |
| » Starters: Vern Kennedy vs Ken Chase | Third | 1 out |
| Wednesday, May 6 |
| » Defeated White Sox (4-18), 3-1 | Fenway Park (11-5) | 14-7 | Won 5 |
| » Starters: Ted Lyons vs Joe Dobson | Second | ½ out |
| Friday, May 8 |
| » Lost to Athletics (9-16), 2-1 | Shibe Park (0-1) | 14-8 | |
| » Starters: Charlie Wagner vs Phil Marchildon | Third | 1 out |
| Sunday, May 10 |
| » Lost to Athletics (10-16), 4-2 | Shibe Park (0-2) | 14-9 | Lost 2 |
| » Starters: Dick Newsome vs Roger Wolff | Fourth | 3 out |
| » Lost to Athletics (11-16), 6-5 | Shibe Park (0-3) | 14-10 | Lost 3 |
| » Starters: Joe Dobson vs Russ Christopher | Fourth | 3 out |
| Wednesday, May 13 |
| » Lost to White Sox (7-19), 2-1 | Comiskey Park I (0-1) | 14-11 | Lost 4 |
| » Starters: Charlie Wagner vs Johnny Humphries | Fourth | 3 out |
| Thursday, May 14 |
| » Lost to Browns (12-18), 6-3 | Sportsman's Park III (0-1) | 14-12 | Lost 5 |
| » Starters: Dick Newsome vs Johnny Niggeling | Fourth | 3½ out |
| Future Red Sox Tony Perez is born in Ciego De Avila, Cuba. |
| Saturday, May 16 |
| » Defeated Browns (12-19), 4-2 | Sportsman's Park III (1-1) | 15-12 | |
| » Starters: Tex Hughson vs Bob Muncrief | Fourth | 4 out |
| Sunday, May 17 |
| » Lost to Tigers (19-14), 4-3 | Tiger Stadium (0-1) | 15-13 | |
| » Starters: Dick Newsome vs Tommy Bridges | Fourth | 4½ out |
| Monday, May 18 |
| » Defeated Tigers (19-15), 4-2 | Tiger Stadium (1-1) | 16-13 | |
| » Starters: Charlie Wagner vs Hal White | Fourth | 4 out |
| Tuesday, May 19 |
| » Lost to Tigers (20-15), 5-2 | Tiger Stadium (1-2) | 16-14 | |
| » Starters: Yank Terry vs Hal Newhouser | Fourth | 4½ out |
| Wednesday, May 20 |
| Former Red Sox Amby McConnell dies in Utica, NY at the age of 60. |
| Thursday, May 21 |
| » Defeated Indians (22-11), 8-3 | League Park II (1-0) | 17-14 | |
| » Starters: Tex Hughson vs Mel Harder | Third | 5 out |
| Saturday, May 23 |
| » Lost to Athletics (16-22), 4-3 | Fenway Park (11-6) | 17-15 | |
| » Starters: Roger Wolff vs Dick Newsome | Third | 6 out |
| Sunday, May 24 |
| » Lost to Athletics (17-22), 6-5 | Fenway Park (11-7) | 17-16 | Lost 2 |
| » Starters: Russ Christopher vs Charlie Wagner | Fourth | 5½ out |
| » Defeated Athletics (17-23), 6-5 | Fenway Park (12-7) | 18-16 | |
| » Starters: Dick Fowler vs Yank Terry | Fourth | 5½ out |
| Monday, May 25 |
| » Lost to Yankees (24-10), 3-1 | Yankee Stadium (2-2) | 18-17 | |
| » Starters: Tex Hughson vs Spud Chandler | Fourth | 6½ out |
| Former Red Sox Bill James dies in Venice, CA at the age of 56. |
| Tuesday, May 26 |
| » Lost to Yankees (25-10), 9-2 | Yankee Stadium (2-3) | 18-18 | Lost 2 |
| » Starters: Joe Dobson vs Atley Donald | Fourth | 7½ out |
| Future Red Sox Chuck Hartenstein is born in Seguin, TX. |
| Wednesday, May 27 |
| » Defeated Senators (16-22), 10-1 | Griffith Stadium (2-1) | 19-18 | |
| » Starters: Oscar Judd vs Bobo Newsom | Fourth | 7½ out |
| Thursday, May 28 |
| » Lost to Senators (17-22), 5-1 | Griffith Stadium (2-2) | 19-19 | |
| » Starters: Charlie Wagner vs Early Wynn | Fourth | 8½ out |
| Friday, May 29 |
| » Defeated Athletics (17-28), 14-2 | Shibe Park (1-3) | 20-19 | |
| » Starters: Tex Hughson vs Russ Christopher | Fourth | 8½ out |
| Saturday, May 30 |
| » Defeated Athletics (17-29), 10-6 | Shibe Park (2-3) | 21-19 | Won 2 |
| » Starters: Ken Chase vs Tex Shirley | Fourth | 9½ out |
| » Lost to Athletics (18-29), 5-4 | Shibe Park (2-4) | 21-20 | |
| » Starters: Yank Terry vs Roger Wolff | Fourth | 9½ out |
| Sunday, May 31 |
| » Defeated Senators (17-26), 11-1 | Fenway Park (13-7) | 22-20 | |
| » Starters: Bobo Newsom vs Oscar Judd | Third | 8½ out |
| » Defeated Senators (17-27), 4-3 | Fenway Park (14-7) | 23-20 | Won 2 |
| » Starters: Bill Zuber vs Bill Butland | Third | 8½ out |
| Tuesday, June 2 |
| » Lost to Indians (25-21), 7-2 | Fenway Park (14-8) | 23-21 | |
| » Starters: Mel Harder vs Charlie Wagner | Fourth | 9 out |
| Thursday, June 4 |
| » Lost to Indians (26-21), 4-2 | Fenway Park (14-9) | 23-22 | Lost 2 |
| » Starters: Jim Bagby vs Oscar Judd | Fourth | 10½ out |
| Friday, June 5 |
| » Defeated White Sox (18-29), 4-2 | Fenway Park (15-9) | 24-22 | |
| » Starters: Johnny Humphries vs Yank Terry | Fourth | 10½ out |
| Saturday, June 6 |
| » Lost to White Sox (19-29), 3-1 | Fenway Park (15-10) | 24-23 | |
| » Starters: Orval Grove vs Tex Hughson | Fourth | 11½ out |
| Sunday, June 7 |
| » Defeated White Sox (19-30), 3-2 | Fenway Park (16-10) | 25-23 | |
| » Starters: Ted Lyons vs Dick Newsome | Third | 10½ out |
| » Defeated White Sox (19-31), 3-2 | Fenway Park (17-10) | 26-23 | Won 2 |
| » Starters: Bill Dietrich vs Charlie Wagner | Third | 10½ out |
| Monday, June 8 |
| Future Red Sox Pete Magrini is born in San Francisco, CA. |
| Tuesday, June 9 |
| » Defeated Browns (28-27), 7-4 | Fenway Park (18-10) | 27-23 | Won 3 |
| » Starters: Elden Auker vs Oscar Judd | Second | 11 out |
| Wednesday, June 10 |
| » Defeated Browns (28-28), 10-3 | Fenway Park (19-10) | 28-23 | Won 4 |
| » Starters: Johnny Niggeling vs Tex Hughson | Second | 10 out |
| Thursday, June 11 |
| » Defeated Browns (28-29), 8-7 | Fenway Park (20-10) | 29-23 | Won 5 |
| » Starters: Bob Muncrief vs Yank Terry | Second | 9½ out |
| Saturday, June 13 |
| » Defeated Tigers (31-28), 6-5 | Fenway Park (21-10) | 30-23 | Won 6 |
| » Starters: Virgil Trucks vs Charlie Wagner | Second | 9½ out |
| Sunday, June 14 |
| » Defeated Tigers (31-29), 3-2 | Fenway Park (22-10) | 31-23 | Won 7 |
| » Starters: Tommy Bridges vs Dick Newsome | Second | 9½ out |
| » Defeated Tigers (31-30), 2-1 | Fenway Park (23-10) | 32-23 | Won 8 |
| » Starters: Hal White vs Tex Hughson | Second | 9½ out |
| Tuesday, June 16 |
| » Defeated Browns (28-33), 4-2 | Sportsman's Park III (2-1) | 33-23 | Won 9 |
| » Starters: Oscar Judd vs Bob Muncrief | Second | 9 out |
| Wednesday, June 17 |
| » Lost to Browns (29-33), 6-3 | Sportsman's Park III (2-2) | 33-24 | |
| » Starters: Bill Butland vs Elden Auker | Second | 9 out |
| Friday, June 19 |
| » Defeated White Sox (24-35), 1-0 | Comiskey Park I (1-1) | 34-24 | |
| » Starters: Charlie Wagner vs Eddie Smith | Second | 7½ out |
| Sunday, June 21 |
| » Lost to White Sox (25-35), 6-5 | Comiskey Park I (1-2) | 34-25 | |
| » Starters: Dick Newsome vs Ted Lyons | Second | 7 out |
| » Defeated White Sox (25-36), 7-0 | Comiskey Park I (2-2) | 35-25 | |
| » Starters: Tex Hughson vs Orval Grove | Second | 7 out |
| Tuesday, June 23 |
| » Defeated Tigers (37-33), 6-2 | Tiger Stadium (2-2) | 36-25 | Won 2 |
| » Starters: Oscar Judd vs Dizzy Trout | Second | 7 out |
| Wednesday, June 24 |
| » Defeated Tigers (37-34), 1-0 | Tiger Stadium (3-2) | 37-25 | Won 3 |
| » Starters: Charlie Wagner vs Virgil Trucks | Second | 7 out |
| Thursday, June 25 |
| » Lost to Tigers (38-34), 7-3 | Tiger Stadium (3-3) | 37-26 | |
| » Starters: Tex Hughson vs Hal White | Second | 7½ out |
| Friday, June 26 |
| » Defeated Indians (38-31), 3-2 | Cleveland Stadium (1-0) | 38-26 | |
| » Starters: Dick Newsome vs Mel Harder | Second | 6½ out |
| Saturday, June 27 |
| » Defeated Indians (38-32), 6-3 | Cleveland Stadium (2-0) | 39-26 | Won 2 |
| » Starters: Ken Chase vs Chubby Dean | Second | 6½ out |
| Sunday, June 28 |
| » Defeated Indians (38-33), 8-3 | Cleveland Stadium (3-0) | 40-26 | Won 3 |
| » Starters: Oscar Judd vs Jim Bagby | Second | 5½ out |
| » Lost to Indians (39-33), 3-2 | Cleveland Stadium (3-1) | 40-27 | |
| » Starters: Charlie Wagner vs Vern Kennedy | Second | 5½ out |
| Tuesday, June 30 |
| » Defeated Senators (26-45), 9-8 | Fenway Park (24-10) | 41-27 | |
| » Starters: Early Wynn vs Dick Newsome | Second | 4½ out |
| » Defeated Senators (26-46), 5-2 | Fenway Park (25-10) | 42-27 | Won 2 |
| » Starters: Sid Hudson vs Tex Hughson | Second | 4½ out |
| Wednesday, July 1 |
| » Defeated Senators (26-47), 3-2 | Fenway Park (26-10) | 43-27 | Won 3 |
| » Starters: Bobo Newsom vs Ken Chase | Second | 3 out |
| » Defeated Senators (26-48), 7-1 | Fenway Park (27-10) | 44-27 | Won 4 |
| » Starters: Jack Wilson vs Joe Dobson | Second | 3 out |
| Friday, July 3 |
| » Lost to Yankees (48-24), 5-3 | Fenway Park (27-11) | 44-28 | |
| » Starters: Spud Chandler vs Charlie Wagner | Second | 4 out |
| Saturday, July 4 |
| » Lost to Yankees (49-24), 6-3 | Fenway Park (27-12) | 44-29 | Lost 2 |
| » Starters: Red Ruffing vs Oscar Judd | Second | 4 out |
| » Defeated Yankees (49-25), 6-4 | Fenway Park (28-12) | 45-29 | |
| » Starters: Tiny Bonham vs Tex Hughson | Second | 4 out |
| Sunday, July 5 |
| » Lost to Senators (29-49), 4-3 | Griffith Stadium (2-3) | 45-30 | |
| » Starters: Dick Newsome vs Bobo Newsom | Second | 4 out |
| » Defeated Senators (29-50), 5-0 | Griffith Stadium (3-3) | 46-30 | |
| » Starters: Joe Dobson vs Alex Carrasquel | Second | 4 out |
| Thursday, July 9 |
| » Defeated Tigers (44-39), 2-1 | Fenway Park (29-12) | 47-30 | Won 2 |
| » Starters: Hal Newhouser vs Charlie Wagner | Second | 4 out |
| Friday, July 10 |
| » Defeated Tigers (44-40), 6-1 | Fenway Park (30-12) | 48-30 | Won 3 |
| » Starters: Dizzy Trout vs Tex Hughson | Second | 4 out |
| Sunday, July 12 |
| » Lost to Browns (39-43), 1-0 | Fenway Park (30-13) | 48-31 | |
| » Starters: Denny Galehouse vs Dick Newsome | Second | 4½ out |
| » Lost to Browns (40-43), 10-6 | Fenway Park (30-14) | 48-32 | Lost 2 |
| » Starters: Steve Sundra vs Joe Dobson | Second | 4½ out |
| Tuesday, July 14 |
| » Lost to Browns (41-43), 3-2 | Fenway Park (30-15) | 48-33 | Lost 3 |
| » Starters: Johnny Niggeling vs Oscar Judd | Second | 6 out |
| Wednesday, July 15 |
| » Defeated White Sox (34-47), 10-1 | Fenway Park (31-15) | 49-33 | |
| » Starters: Eddie Smith vs Tex Hughson | Second | 6½ out |
| » Lost to White Sox (35-47), 11-6 | Fenway Park (31-16) | 49-34 | |
| » Starters: Bill Dietrich vs Charlie Wagner | Second | 6½ out |
| Thursday, July 16 |
| » Lost to White Sox (36-47), 3-2 | Fenway Park (31-17) | 49-35 | Lost 2 |
| » Starters: Buck Ross vs Dick Newsome | Second | 7½ out |
| Friday, July 17 |
| » Defeated White Sox (36-48), 2-1 | Fenway Park (32-17) | 50-35 | |
| » Starters: Johnny Humphries vs Charlie Wagner | Second | 7½ out |
| Sunday, July 19 |
| » Lost to Indians (50-40), 10-7 | Fenway Park (32-18) | 50-36 | |
| » Starters: Jim Bagby vs Tex Hughson | Second | 10 out |
| » Lost to Indians (51-40), 4-0 | Fenway Park (32-19) | 50-37 | Lost 2 |
| » Starters: Mel Harder vs Oscar Judd | Second | 10 out |
| Tuesday, July 21 |
| » Lost to White Sox (37-51), 5-4 | Comiskey Park I (2-3) | 50-38 | Lost 3 |
| » Starters: Dick Newsome vs Johnny Humphries | Second | 11 out |
| Wednesday, July 22 |
| » Lost to White Sox (38-51), 2-0 | Comiskey Park I (2-4) | 50-39 | Lost 4 |
| » Starters: Charlie Wagner vs Buck Ross | Second | 12 out |
| Thursday, July 23 |
| » Defeated White Sox (38-52), 5-4 | Comiskey Park I (3-4) | 51-39 | |
| » Starters: Tex Hughson vs Bill Dietrich | Second | 11 out |
| Friday, July 24 |
| » Defeated Browns (49-46), 5-3 | Sportsman's Park III (3-2) | 52-39 | Won 2 |
| » Starters: Ken Chase vs Bob Muncrief | Second | 11½ out |
| » Lost to Browns (50-46), 3-1 | Sportsman's Park III (3-3) | 52-40 | |
| » Starters: Joe Dobson vs Johnny Niggeling | Second | 11½ out |
| Saturday, July 25 |
| » Defeated Browns (50-47), 9-8 | Sportsman's Park III (4-3) | 53-40 | |
| » Starters: Oscar Judd vs Elden Auker | Second | 11½ out |
| Sunday, July 26 |
| » Lost to Browns (51-47), 9-2 | Sportsman's Park III (4-4) | 53-41 | |
| » Starters: Dick Newsome vs Denny Galehouse | Second | 13 out |
| » Lost to Browns (52-47), 4-3 | Sportsman's Park III (4-5) | 53-42 | Lost 2 |
| » Starters: Charlie Wagner vs Al Hollingsworth | Second | 13 out |
| Monday, July 27 |
| » Defeated Indians (55-45), 8-5 | League Park II (2-0) | 54-42 | |
| » Starters: Tex Hughson vs Al Milnar | Second | 12½ out |
| Tuesday, July 28 |
| » Defeated Indians (55-46), 3-1 | Cleveland Stadium (4-1) | 55-42 | Won 2 |
| » Starters: Joe Dobson vs Jim Bagby | Second | 12½ out |
| Wednesday, July 29 |
| » Lost to Indians (56-46), 7-6 | League Park II (2-1) | 55-43 | |
| » Starters: Ken Chase vs Chubby Dean | Second | 12 out |
| Thursday, July 30 |
| » Lost to Indians (57-46), 4-3 | League Park II (2-2) | 55-44 | Lost 2 |
| » Starters: Oscar Judd vs Mel Harder | Second | 12½ out |
| Friday, July 31 |
| » Defeated Tigers (49-54), 7-6 | Tiger Stadium (4-3) | 56-44 | |
| » Starters: Tex Hughson vs Al Benton | Second | 12 out |
| Saturday, August 1 |
| » Defeated Tigers (49-55), 9-8 | Tiger Stadium (5-3) | 57-44 | Won 2 |
| » Starters: Charlie Wagner vs Hal Newhouser | Second | 11 out |
| Sunday, August 2 |
| » Lost to Tigers (50-55), 8-4 | Tiger Stadium (5-4) | 57-45 | |
| » Starters: Dick Newsome vs Dizzy Trout | Third | 13 out |
| » Lost to Tigers (51-55), 6-2 | Tiger Stadium (5-5) | 57-46 | Lost 2 |
| » Starters: Joe Dobson vs Virgil Trucks | Third | 13 out |
| Tuesday, August 4 |
| » Lost to Athletics (43-67), 6-4 | Fenway Park (32-20) | 57-47 | Lost 3 |
| » Starters: Phil Marchildon vs Charlie Wagner | Third | 13 out |
| Wednesday, August 5 |
| » Defeated Athletics (43-68), 7-0 | Fenway Park (33-20) | 58-47 | |
| » Starters: Roger Wolff vs Tex Hughson | Third | 12½ out |
| Thursday, August 6 |
| » Defeated Athletics (43-69), 2-0 | Fenway Park (34-20) | 59-47 | Won 2 |
| » Starters: Russ Christopher vs Bill Butland | Third | 11½ out |
| Monday, August 10 |
| » Lost to Senators (44-61), 9-3 | Griffith Stadium (3-4) | 59-48 | |
| » Starters: Oscar Judd vs Sid Hudson | Second | 13 out |
| » Lost to Senators (45-61), 1-0 | Griffith Stadium (3-5) | 59-49 | Lost 2 |
| » Starters: Joe Dobson vs Walt Masterson | Second | 13 out |
| Tuesday, August 11 |
| » Defeated Yankees (72-37), 3-2 | Yankee Stadium (3-3) | 60-49 | |
| » Starters: Tex Hughson vs Marv Breuer | Second | 12 out |
| Wednesday, August 12 |
| » Lost to Yankees (73-37), 8-4 | Yankee Stadium (3-4) | 60-50 | |
| » Starters: Ken Chase vs Hank Borowy | Second | 13 out |
| Saturday, August 15 |
| » Defeated Senators (46-62), 2-1 | Fenway Park (35-20) | 61-50 | |
| » Starters: Sid Hudson vs Tex Hughson | Second | 12½ out |
| » Defeated Senators (46-63), 7-6 | Fenway Park (36-20) | 62-50 | Won 2 |
| » Starters: Alex Carrasquel vs Joe Dobson | Second | 12½ out |
| Sunday, August 16 |
| » Defeated Senators (46-64), 6-4 | Fenway Park (37-20) | 63-50 | Won 3 |
| » Starters: Walt Masterson vs Bill Butland | Second | 12 out |
| » Defeated Senators (46-65), 10-3 | Fenway Park (38-20) | 64-50 | Won 4 |
| » Starters: Bobo Newsom vs Yank Terry | Second | 12 out |
| Tuesday, August 18 |
| » Defeated Yankees (77-39), 8-7 | Fenway Park (39-20) | 65-50 | Won 5 |
| » Starters: Hank Borowy vs Dick Newsome | Second | 11½ out |
| Wednesday, August 19 |
| » Defeated Yankees (77-40), 6-4 | Fenway Park (40-20) | 66-50 | Won 6 |
| » Starters: Spud Chandler vs Tex Hughson | Second | 11½ out |
| » Lost to Yankees (78-40), 2-1 | Fenway Park (40-21) | 66-51 | |
| » Starters: Tiny Bonham vs Joe Dobson | Second | 11½ out |
| Thursday, August 20 |
| » Defeated Yankees (78-41), 7-4 | Fenway Park (41-21) | 67-51 | |
| » Starters: Marv Breuer vs Bill Butland | Second | 10½ out |
| Friday, August 21 |
| » Defeated Athletics (48-78), 7-5 | Shibe Park (3-4) | 68-51 | Won 2 |
| » Starters: Charlie Wagner vs Dick Fowler | Second | 10½ out |
| Saturday, August 22 |
| » Defeated Athletics (48-79), 11-3 | Shibe Park (4-4) | 69-51 | Won 3 |
| » Starters: Yank Terry vs Jack Knott | Second | 10 out |
| » Defeated Athletics (48-80), 11-5 | Shibe Park (5-4) | 70-51 | Won 4 |
| » Starters: Dick Newsome vs Lum Harris | Second | 10 out |
| Sunday, August 23 |
| » Defeated Athletics (48-81), 2-0 | Shibe Park (6-4) | 71-51 | Won 5 |
| » Starters: Tex Hughson vs Roger Wolff | Second | 9 out |
| » Defeated Athletics (48-82), 7-0 | Shibe Park (7-4) | 72-51 | Won 6 |
| » Starters: Joe Dobson vs Phil Marchildon | Second | 9 out |
| Tuesday, August 25 |
| » Defeated Indians (64-59), 4-3 | Fenway Park (42-21) | 73-51 | Won 7 |
| » Starters: Tom Ferrick vs Ken Chase | Second | 8½ out |
| » Defeated Indians (64-60), 5-1 | Fenway Park (43-21) | 74-51 | Won 8 |
| » Starters: Vern Kennedy vs Oscar Judd | Second | 8½ out |
| Wednesday, August 26 |
| » Defeated Indians (64-61), 4-1 | Fenway Park (44-21) | 75-51 | Won 9 |
| » Starters: Mel Harder vs Bill Butland | Second | 7½ out |
| Thursday, August 27 |
| » Lost to Indians (65-61), 4-2 | Fenway Park (44-22) | 75-52 | |
| » Starters: Jim Bagby vs Tex Hughson | Second | 8 out |
| Friday, August 28 |
| » Defeated White Sox (54-66), 4-0 | Fenway Park (45-22) | 76-52 | |
| » Starters: Buck Ross vs Joe Dobson | Second | 8 out |
| Saturday, August 29 |
| » Defeated White Sox (54-67), 4-2 | Fenway Park (46-22) | 77-52 | Won 2 |
| » Starters: Jake Wade vs Charlie Wagner | Second | 7 out |
| » Major-league debuts: Bill Mueller (White Sox) |
| Sunday, August 30 |
| » Lost to Browns (68-59), 4-1 | Fenway Park (46-23) | 77-53 | |
| » Starters: Johnny Niggeling vs Ken Chase | Second | 8 out |
| » Defeated Browns (68-60), 12-6 | Fenway Park (47-23) | 78-53 | |
| » Starters: Denny Galehouse vs Bill Butland | Second | 8 out |
| Monday, August 31 |
| » Defeated Browns (68-61), 8-6 | Fenway Park (48-23) | 79-53 | Won 2 |
| » Starters: Bob Muncrief vs Tex Hughson | Second | 8 out |
| Wednesday, September 2 |
| » Defeated Tigers (64-69), 3-2 | Fenway Park (49-23) | 80-53 | Won 3 |
| » Starters: Al Benton vs Charlie Wagner | Second | 8 out |
| » Defeated Tigers (64-70), 4-2 | Fenway Park (50-23) | 81-53 | Won 4 |
| » Starters: Hal White vs Joe Dobson | Second | 8 out |
| Thursday, September 3 |
| » Defeated Tigers (64-71), 2-0 | Fenway Park (51-23) | 82-53 | Won 5 |
| » Starters: Hal Newhouser vs Bill Butland | Second | 7½ out |
| Saturday, September 5 |
| » Lost to Athletics (50-89), 4-3 | Fenway Park (51-24) | 82-54 | |
| » Starters: Phil Marchildon vs Tex Hughson | Second | 8 out |
| Future Red Sox Dave Morehead is born in San Diego, CA. |
| Sunday, September 6 |
| » Defeated Athletics (50-90), 8-7 | Fenway Park (52-24) | 83-54 | |
| » Starters: Bob Savage vs Charlie Wagner | Second | 8½ out |
| Monday, September 7 |
| » Defeated Senators (54-81), 9-7 | Griffith Stadium (4-5) | 84-54 | Won 2 |
| » Starters: Joe Dobson vs Sid Hudson | Second | 9 out |
| Tuesday, September 8 |
| » Lost to Senators (55-81), 15-11 | Griffith Stadium (4-6) | 84-55 | |
| » Starters: Oscar Judd vs Ray Scarborough | Second | 9½ out |
| Thursday, September 10 |
| » Lost to Tigers (68-73), 5-4 | Tiger Stadium (5-6) | 84-56 | Lost 2 |
| » Starters: Tex Hughson vs Hal Newhouser | Second | 10 out |
| Friday, September 11 |
| » Defeated Indians (70-71), 15-2 | League Park II (3-2) | 85-56 | |
| » Starters: Ken Chase vs Jim Bagby | Second | 9 out |
| Saturday, September 12 |
| » Defeated Indians (70-72), 8-6 | League Park II (4-2) | 86-56 | Won 2 |
| » Starters: Joe Dobson vs Mel Harder | Second | 9 out |
| Sunday, September 13 |
| » Defeated White Sox (61-76), 6-1 | Comiskey Park I (4-4) | 87-56 | Won 3 |
| » Starters: Bill Butland vs Buck Ross | Second | 9 out |
| » Defeated White Sox (61-77), 5-0 | Comiskey Park I (5-4) | 88-56 | Won 4 |
| » Starters: Tex Hughson vs Bill Dietrich | Second | 9 out |
| Monday, September 14 |
| » Lost to White Sox (62-77), 4-0 | Comiskey Park I (5-5) | 88-57 | |
| » Starters: Dick Newsome vs Johnny Humphries | Second | 10 out |
| Wednesday, September 16 |
| » Lost to Browns (81-67), 3-0 | Sportsman's Park III (4-6) | 88-58 | Lost 2 |
| » Starters: Joe Dobson vs Johnny Niggeling | Second | 11 out |
| Thursday, September 17 |
| » Defeated Browns (81-68), 5-1 | Sportsman's Park III (5-6) | 89-58 | |
| » Starters: Tex Hughson vs Denny Galehouse | Second | 11 out |
| Saturday, September 19 |
| » Defeated Yankees (100-48), 9-6 | Yankee Stadium (4-4) | 90-58 | Won 2 |
| » Starters: Bill Butland vs Spud Chandler | Second | 10 out |
| Sunday, September 20 |
| » Lost to Yankees (101-48), 2-1 | Yankee Stadium (4-5) | 90-59 | |
| » Starters: Joe Dobson vs Red Ruffing | Second | 10 out |
| » Defeated Yankees (101-49), 3-2 | Yankee Stadium (5-5) | 91-59 | |
| » Starters: Yank Terry vs Hank Borowy | Second | 10 out |
| Monday, September 21 |
| » Defeated Yankees (101-50), 3-2 | Yankee Stadium (6-5) | 92-59 | Won 2 |
| » Starters: Tex Hughson vs Marv Breuer | Second | 9 out |
| Sunday, September 27 |
| » Defeated Yankees (103-51), 7-6 | Fenway Park (53-24) | 93-59 | Won 3 |
| » Starters: Marius Russo vs Tex Hughson | Second | 9 out |
| Thursday, October 8 |
| Future Red Sox Bill Landis is born in Hanford, CA. |
| Tuesday, October 13 |
| Future Red Sox Bob Bailey is born in Long Beach, CA. |
| Friday, November 6 |
| Future Red Sox Jim Gosger is born in Port Huron, MI. |
| Saturday, December 5 |
| Former Red Sox Val Picinich dies in Nobleboro, ME at the age of 47. |
| Sunday, December 13 |
| Future Red Sox Ferguson Jenkins is born in Chatham, ON. |
Game information provided by Retrosheet (www.retrosheet.org) |