| Tuesday, February 11 |
| Future White Sox Sammy Ellis is born in Youngstown, OH. |
| Wednesday, March 5 |
| Future White Sox Phil Roof is born in Paducah, KY. |
| Friday, April 4 |
| Future White Sox Eddie Watt is born in Lamoni, IA. |
| Monday, April 14 |
| » Major-league debuts: Phil Rizzuto and Johnny Sturm (Yankees) |
| Tuesday, April 15 |
| » Defeated Indians (0-1), 4-3 | Cleveland Stadium (1-0) | 1-0 | |
| » Starters: Bill Dietrich vs Bob Feller | First | -- |
| Wednesday, April 16 |
| » Lost to Indians (1-1), 6-0 | League Park II (0-1) | 1-1 | |
| » Starters: Eddie Smith vs Al Milnar | Third | 1 out |
| Thursday, April 17 |
| » Lost to Indians (2-1), 2-0 | League Park II (0-2) | 1-2 | Lost 2 |
| » Starters: Thornton Lee vs Al Smith | Fifth | 1½ out |
| Friday, April 18 |
| » Defeated Browns (1-1), 6-3 | Comiskey Park I (1-0) | 2-2 | |
| » Starters: Vern Kennedy vs Ted Lyons | Third | 1½ out |
| Tuesday, April 22 |
| » Defeated Tigers (1-4), 6-3 | Tiger Stadium (1-0) | 3-2 | Won 2 |
| » Starters: Bill Dietrich vs Bobo Newsom | Third | 1 out |
| » Major-league debuts: Hal White (Tigers) |
| Future White Sox Steve Jones is born in Huntington Park, CA. |
| Wednesday, April 23 |
| » Lost to Tigers (2-4), 13-5 | Tiger Stadium (1-1) | 3-3 | |
| » Starters: Jack Hallett vs Hal Newhouser | Fourth | 1 out |
| Thursday, April 24 |
| » Defeated Indians (5-4), 2-1 | Comiskey Park I (2-0) | 4-3 | |
| » Starters: Al Smith vs Thornton Lee | Second | 2 out |
| Friday, April 25 |
| » Lost to Indians (6-4), 5-3 | Comiskey Park I (2-1) | 4-4 | |
| » Starters: Jim Bagby vs Ted Lyons | Third | 2 out |
| Saturday, April 26 |
| » Defeated Browns (2-5), 2-1 | Sportsman's Park III (1-0) | 5-4 | |
| » Starters: Eddie Smith vs George Caster | Third | 2 out |
| Sunday, April 27 |
| » Defeated Browns (2-6), 7-6 | Sportsman's Park III (2-0) | 6-4 | Won 2 |
| » Starters: Bill Dietrich vs Elden Auker | Fourth | 1 out |
| Monday, April 28 |
| » Defeated Browns (2-7), 2-1 | Sportsman's Park III (3-0) | 7-4 | Won 3 |
| » Starters: Jack Hallett vs Vern Kennedy | Third | 1 out |
| Tuesday, April 29 |
| » Defeated Senators (4-9), 3-2 | Comiskey Park I (3-1) | 8-4 | Won 4 |
| » Starters: Walt Masterson vs Thornton Lee | Second | 1 out |
| Wednesday, April 30 |
| » Defeated Senators (4-10), 5-1 | Comiskey Park I (4-1) | 9-4 | Won 5 |
| » Starters: Ken Chase vs Eddie Smith | Second | 1 out |
| Thursday, May 1 |
| » Lost to Senators (5-10), 7-0 | Comiskey Park I (4-2) | 9-5 | |
| » Starters: Dutch Leonard vs Bill Dietrich | Third | 2 out |
| Friday, May 2 |
| » Defeated Yankees (11-7), 8-1 | Comiskey Park I (5-2) | 10-5 | |
| » Starters: Red Ruffing vs Ted Lyons | Second | 2 out |
| Future White Sox Clay Carroll is born in Clanton, AL. |
| Saturday, May 3 |
| » Lost to Yankees (12-7), 6-5 | Comiskey Park I (5-3) | 10-6 | |
| » Starters: Spud Chandler vs Thornton Lee | Third | 3 out |
| Sunday, May 4 |
| » Lost to Athletics (5-12), 17-11 | Comiskey Park I (5-4) | 10-7 | Lost 2 |
| » Starters: Bill Beckmann vs Jack Hallett | Third | 4 out |
| Monday, May 5 |
| » Lost to Athletics (6-12), 5-4 | Comiskey Park I (5-5) | 10-8 | Lost 3 |
| » Starters: Les McCrabb vs Eddie Smith | Third | 5 out |
| Wednesday, May 7 |
| » Lost to Red Sox (10-8), 4-3 | Comiskey Park I (5-6) | 10-9 | Lost 4 |
| » Starters: Charlie Wagner vs Johnny Rigney | Fifth | 4½ out |
| Saturday, May 10 |
| » Defeated Tigers (11-11), 4-3 | Comiskey Park I (6-6) | 11-9 | |
| » Starters: Hal Newhouser vs Thornton Lee | Fourth | 3½ out |
| Future White Sox Ken Berry is born in Kansas City, MO. |
| Sunday, May 11 |
| » Defeated Tigers (11-12), 2-1 | Comiskey Park I (7-6) | 12-9 | Won 2 |
| » Starters: Tommy Bridges vs Ted Lyons | Third | 3 out |
| Monday, May 12 |
| Future White Sox Floyd Weaver is born in Ben Franklin, TX. |
| Tuesday, May 13 |
| » Defeated Red Sox (12-9), 3-2 | Fenway Park (1-0) | 13-9 | Won 3 |
| » Starters: Johnny Rigney vs Charlie Wagner | Second | 3 out |
| Wednesday, May 14 |
| » Lost to Red Sox (13-9), 10-7 | Fenway Park (1-1) | 13-10 | |
| » Starters: Bill Dietrich vs Emerson Dickman | Third | 4 out |
| Thursday, May 15 |
| » Defeated Yankees (14-15), 13-1 | Yankee Stadium (1-0) | 14-10 | |
| » Starters: Eddie Smith vs Tiny Bonham | Second | 4 out |
| Friday, May 16 |
| » Lost to Yankees (15-15), 6-5 | Yankee Stadium (1-1) | 14-11 | |
| » Starters: Thornton Lee vs Marv Breuer | Second | 5 out |
| Saturday, May 17 |
| » Defeated Yankees (15-16), 3-2 | Yankee Stadium (2-1) | 15-11 | |
| » Starters: Johnny Rigney vs Spud Chandler | Second | 5 out |
| Sunday, May 18 |
| » Defeated Senators (14-17), 10-5 | Griffith Stadium (1-0) | 16-11 | Won 2 |
| » Starters: Bill Dietrich vs Steve Sundra | Second | 4 out |
| Monday, May 19 |
| » Defeated Senators (14-18), 8-2 | Griffith Stadium (2-0) | 17-11 | Won 3 |
| » Starters: Eddie Smith vs Vern Kennedy | Second | 3 out |
| Tuesday, May 20 |
| » Defeated Senators (14-19), 5-2 | Griffith Stadium (3-0) | 18-11 | Won 4 |
| » Starters: Thornton Lee vs Dutch Leonard | Second | 3 out |
| Wednesday, May 21 |
| » Lost to Athletics (14-18), 7-6 | Shibe Park (0-1) | 18-12 | |
| » Starters: Jack Hallett vs Phil Marchildon | Second | 3 out |
| Thursday, May 22 |
| » Defeated Athletics (14-19), 4-1 | Shibe Park (1-1) | 19-12 | |
| » Starters: Johnny Rigney vs Bill Beckmann | Second | 3 out |
| Friday, May 23 |
| » Defeated Tigers (16-18), 7-1 | Tiger Stadium (2-1) | 20-12 | Won 2 |
| » Starters: Ted Lyons vs Tommy Bridges | Second | 3½ out |
| » Lost to Tigers (17-18), 9-0 | Tiger Stadium (2-2) | 20-13 | |
| » Starters: Bill Dietrich vs Dizzy Trout | Second | 3½ out |
| Saturday, May 24 |
| » Lost to Tigers (18-18), 1-0 | Tiger Stadium (2-3) | 20-14 | Lost 2 |
| » Starters: Eddie Smith vs Johnny Gorsica | Second | 4½ out |
| Sunday, May 25 |
| » Defeated Tigers (18-19), 7-3 | Tiger Stadium (3-3) | 21-14 | |
| » Starters: Thornton Lee vs Hal Newhouser | Second | 4½ out |
| Tuesday, May 27 |
| » Lost to Browns (12-23), 5-2 | Comiskey Park I (7-7) | 21-15 | |
| » Starters: Bob Muncrief vs Johnny Rigney | Second | 4 out |
| Wednesday, May 28 |
| » Lost to Browns (13-23), 8-4 | Comiskey Park I (7-8) | 21-16 | Lost 2 |
| » Starters: Denny Galehouse vs Eddie Smith | Second | 4 out |
| Thursday, May 29 |
| » Defeated Browns (13-24), 4-0 | Comiskey Park I (8-8) | 22-16 | |
| » Starters: George Caster vs Bill Dietrich | Second | 4 out |
| Friday, May 30 |
| » Defeated Indians (29-16), 7-1 | Comiskey Park I (9-8) | 23-16 | Won 2 |
| » Starters: Al Smith vs Ted Lyons | Second | 3 out |
| » Defeated Indians (29-17), 5-2 | Comiskey Park I (10-8) | 24-16 | Won 3 |
| » Starters: Jim Bagby vs Thornton Lee | Second | 3 out |
| Saturday, May 31 |
| » Defeated Browns (13-27), 4-3 | Comiskey Park I (11-8) | 25-16 | Won 4 |
| » Starters: Bob Harris vs Jack Hallett | Second | 2½ out |
| Sunday, June 1 |
| » Lost to Senators (15-28), 3-2 | Comiskey Park I (11-9) | 25-17 | |
| » Starters: Sid Hudson vs Johnny Rigney | First | -- |
| » Defeated Senators (15-29), 4-3 | Comiskey Park I (12-9) | 26-17 | |
| » Starters: Ken Chase vs Eddie Smith | First | -- |
| Monday, June 2 |
| » Lost to Senators (16-29), 8-3 | Comiskey Park I (12-10) | 26-18 | |
| » Starters: Steve Sundra vs Bill Dietrich | Second | 2½ out |
| Wednesday, June 4 |
| » Defeated Athletics (23-22), 6-1 | Comiskey Park I (13-10) | 27-18 | |
| » Starters: Les McCrabb vs Thornton Lee | Second | 2 out |
| Thursday, June 5 |
| » Lost to Athletics (24-22), 9-3 | Comiskey Park I (13-11) | 27-19 | |
| » Starters: Jack Knott vs Eddie Smith | Second | 2 out |
| Friday, June 6 |
| » Lost to Red Sox (24-19), 6-3 | Comiskey Park I (13-12) | 27-20 | Lost 2 |
| » Starters: Joe Dobson vs Johnny Rigney | Second | 2 out |
| Saturday, June 7 |
| » Defeated Red Sox (24-20), 5-4 | Comiskey Park I (14-12) | 28-20 | |
| » Starters: Jack Wilson vs Eddie Smith | Second | 2 out |
| Sunday, June 8 |
| » Lost to Red Sox (25-20), 5-3 | Comiskey Park I (14-13) | 28-21 | |
| » Starters: Lefty Grove vs Ted Lyons | Third | 4 out |
| » Lost to Red Sox (26-20), 3-0 | Comiskey Park I (14-14) | 28-22 | Lost 2 |
| » Starters: Dick Newsome vs Thornton Lee | Third | 4 out |
| Tuesday, June 10 |
| » Lost to Yankees (29-22), 8-3 | Comiskey Park I (14-15) | 28-23 | Lost 3 |
| » Starters: Steve Peek vs Johnny Rigney | Fourth | 5 out |
| Thursday, June 12 |
| » Lost to Yankees (30-22), 3-2 | Comiskey Park I (14-16) | 28-24 | Lost 4 |
| » Starters: Spud Chandler vs Thornton Lee | Fourth | 6 out |
| Saturday, June 14 |
| » Defeated Red Sox (27-22), 5-2 | Fenway Park (2-1) | 29-24 | |
| » Starters: Eddie Smith vs Mickey Harris | Fourth | 5 out |
| Sunday, June 15 |
| » Lost to Red Sox (28-22), 8-6 | Fenway Park (2-2) | 29-25 | |
| » Starters: Ted Lyons vs Lefty Grove | Fifth | 5½ out |
| » Lost to Red Sox (29-22), 6-4 | Fenway Park (2-3) | 29-26 | Lost 2 |
| » Starters: Buck Ross vs Dick Newsome | Fifth | 5½ out |
| Tuesday, June 17 |
| » Defeated Yankees (33-23), 8-7 | Yankee Stadium (3-1) | 30-26 | |
| » Starters: Johnny Rigney vs Steve Peek | Fourth | 5 out |
| Wednesday, June 18 |
| » Defeated Yankees (33-24), 3-2 | Yankee Stadium (4-1) | 31-26 | Won 2 |
| » Starters: Thornton Lee vs Spud Chandler | Fourth | 5 out |
| Thursday, June 19 |
| » Lost to Yankees (34-24), 7-2 | Yankee Stadium (4-2) | 31-27 | |
| » Starters: Eddie Smith vs Marv Breuer | Fourth | 6 out |
| Saturday, June 21 |
| » Lost to Athletics (27-32), 11-5 | Shibe Park (1-2) | 31-28 | Lost 2 |
| » Starters: Jack Hallett vs Jack Knott | Fourth | 5½ out |
| Sunday, June 22 |
| » Defeated Athletics (27-33), 14-0 | Shibe Park (2-2) | 32-28 | |
| » Starters: Ted Lyons vs Johnny Babich | Fourth | 6 out |
| » Lost to Athletics (28-33), 3-0 | Shibe Park (2-3) | 32-29 | |
| » Starters: Eddie Smith vs Phil Marchildon | Fourth | 6 out |
| Tuesday, June 24 |
| » Lost to Senators (23-39), 6-3 | Griffith Stadium (3-1) | 32-30 | Lost 2 |
| » Starters: Thornton Lee vs Dutch Leonard | Fifth | 6 out |
| Wednesday, June 25 |
| » Defeated Senators (23-40), 2-0 | Griffith Stadium (4-1) | 33-30 | |
| » Starters: Johnny Rigney vs Sid Hudson | Fourth | 5 out |
| Thursday, June 26 |
| » Lost to Senators (24-40), 3-2 | Griffith Stadium (4-2) | 33-31 | |
| » Starters: Eddie Smith vs Ken Chase | Fourth | 6 out |
| Friday, June 27 |
| » Lost to Indians (42-27), 3-1 | Cleveland Stadium (1-1) | 33-32 | Lost 2 |
| » Starters: Bill Dietrich vs Al Milnar | Fourth | 7 out |
| Saturday, June 28 |
| » Defeated Indians (42-28), 6-4 | Cleveland Stadium (2-1) | 34-32 | |
| » Starters: Thornton Lee vs Al Smith | Fourth | 6 out |
| Future White Sox Fred Talbot is born in Washington, DC. |
| Sunday, June 29 |
| » Defeated Indians (42-29), 9-3 | Cleveland Stadium (3-1) | 35-32 | Won 2 |
| » Starters: Ted Lyons vs Jim Bagby | Fourth | 6½ out |
| Monday, June 30 |
| » Defeated Tigers (35-36), 7-6 | Comiskey Park I (15-16) | 36-32 | Won 3 |
| » Starters: Johnny Gorsica vs Johnny Rigney | Fourth | 6 out |
| Tuesday, July 1 |
| » Lost to Tigers (36-36), 5-1 | Comiskey Park I (15-17) | 36-33 | |
| » Starters: Dizzy Trout vs Eddie Smith | Fourth | 7½ out |
| Wednesday, July 2 |
| » Lost to Tigers (37-36), 1-0 | Comiskey Park I (15-18) | 36-34 | Lost 2 |
| » Starters: Bobo Newsom vs Bill Dietrich | Fourth | 8½ out |
| Friday, July 4 |
| » Defeated Tigers (37-37), 3-2 | Tiger Stadium (4-3) | 37-34 | |
| » Starters: Thornton Lee vs Tommy Bridges | Fourth | 8½ out |
| » Lost to Tigers (38-37), 10-6 | Tiger Stadium (4-4) | 37-35 | |
| » Starters: Johnny Rigney vs Hal Newhouser | Fourth | 8½ out |
| Saturday, July 5 |
| » Lost to Indians (46-30), 5-3 | Comiskey Park I (15-19) | 37-36 | Lost 2 |
| » Starters: Jim Bagby vs Eddie Smith | Fourth | 9½ out |
| Sunday, July 6 |
| » Defeated Indians (46-31), 9-4 | Comiskey Park I (16-19) | 38-36 | |
| » Starters: Al Milnar vs Ted Lyons | Fourth | 10 out |
| Thursday, July 10 |
| » Defeated Senators (26-48), 5-1 | Comiskey Park I (17-19) | 39-36 | Won 2 |
| » Starters: Ken Chase vs Johnny Rigney | Fourth | 10 out |
| Friday, July 11 |
| » Defeated Senators (26-49), 3-1 | Comiskey Park I (18-19) | 40-36 | Won 3 |
| » Starters: Sid Hudson vs Eddie Smith | Fourth | 10 out |
| Saturday, July 12 |
| » Lost to Senators (27-49), 5-3 | Comiskey Park I (18-20) | 40-37 | |
| » Starters: Dutch Leonard vs Buck Ross | Fourth | 11 out |
| Sunday, July 13 |
| » Lost to Yankees (52-26), 8-1 | Comiskey Park I (18-21) | 40-38 | Lost 2 |
| » Starters: Spud Chandler vs Ted Lyons | Fourth | 13 out |
| » Lost to Yankees (53-26), 1-0 | Comiskey Park I (18-22) | 40-39 | Lost 3 |
| » Starters: Red Ruffing vs Thornton Lee | Fourth | 13 out |
| Monday, July 14 |
| » Defeated Yankees (53-27), 7-1 | Comiskey Park I (19-22) | 41-39 | |
| » Starters: Marv Breuer vs Johnny Rigney | Fourth | 12 out |
| Tuesday, July 15 |
| » Lost to Yankees (54-27), 5-4 | Comiskey Park I (19-23) | 41-40 | |
| » Starters: Steve Peek vs Eddie Smith | Fourth | 13 out |
| Former White Sox Frank Isbell dies in Wichita, KS at the age of 66. |
| Wednesday, July 16 |
| » Lost to Red Sox (44-37), 2-1 | Comiskey Park I (19-24) | 41-41 | Lost 2 |
| » Starters: Tex Hughson vs Buck Ross | Fourth | 14 out |
| Thursday, July 17 |
| » Lost to Red Sox (45-37), 7-4 | Comiskey Park I (19-25) | 41-42 | Lost 3 |
| » Starters: Dick Newsome vs Thornton Lee | Fifth | 15 out |
| Friday, July 18 |
| » Defeated Red Sox (45-38), 4-3 | Comiskey Park I (20-25) | 42-42 | |
| » Starters: Lefty Grove vs Johnny Rigney | Fourth | 14 out |
| Saturday, July 19 |
| » Defeated Athletics (37-46), 4-2 | Comiskey Park I (21-25) | 43-42 | Won 2 |
| » Starters: Phil Marchildon vs Eddie Smith | Fourth | 15 out |
| » Lost to Athletics (38-46), 3-1 | Comiskey Park I (21-26) | 43-43 | |
| » Starters: Lum Harris vs Johnny Humphries | Fourth | 15 out |
| Sunday, July 20 |
| » Defeated Athletics (38-47), 2-1 | Comiskey Park I (22-26) | 44-43 | |
| » Starters: Bill Beckmann vs Ted Lyons | Fourth | 15½ out |
| » Lost to Athletics (39-47), 4-1 | Comiskey Park I (22-27) | 44-44 | |
| » Starters: Bump Hadley vs Buck Ross | Fourth | 15½ out |
| Tuesday, July 22 |
| » Lost to Red Sox (46-42), 6-2 | Fenway Park (2-4) | 44-45 | Lost 2 |
| » Starters: Johnny Rigney vs Dick Newsome | Fourth | 16½ out |
| Wednesday, July 23 |
| » Defeated Red Sox (46-43), 10-4 | Fenway Park (3-4) | 45-45 | |
| » Starters: Thornton Lee vs Tex Hughson | Fourth | 16½ out |
| Thursday, July 24 |
| » Lost to Red Sox (47-43), 11-1 | Fenway Park (3-5) | 45-46 | |
| » Starters: Bill Dietrich vs Mickey Harris | Fourth | 17½ out |
| Friday, July 25 |
| » Lost to Yankees (63-28), 8-0 | Yankee Stadium (4-3) | 45-47 | Lost 2 |
| » Starters: Eddie Smith vs Spud Chandler | Fourth | 18½ out |
| Saturday, July 26 |
| » Lost to Yankees (64-28), 11-3 | Yankee Stadium (4-4) | 45-48 | Lost 3 |
| » Starters: Johnny Rigney vs Marv Breuer | Fourth | 19½ out |
| Sunday, July 27 |
| » Lost to Yankees (65-28), 9-5 | Yankee Stadium (4-5) | 45-49 | Lost 4 |
| » Starters: Ted Lyons vs Red Ruffing | Fifth | 19½ out |
| » Defeated Yankees (65-29), 7-3 | Yankee Stadium (5-5) | 46-49 | |
| » Starters: Thornton Lee vs Tiny Bonham | Fifth | 19½ out |
| Tuesday, July 29 |
| » Defeated Athletics (45-49), 1-0 | Shibe Park (3-3) | 47-49 | Won 2 |
| » Starters: Eddie Smith vs Phil Marchildon | Fourth | 18½ out |
| Wednesday, July 30 |
| » Lost to Athletics (46-49), 5-3 | Shibe Park (3-4) | 47-50 | |
| » Starters: Buck Ross vs Lum Harris | Fourth | 19 out |
| Thursday, July 31 |
| » Lost to Athletics (47-49), 9-2 | Shibe Park (3-5) | 47-51 | Lost 2 |
| » Starters: Johnny Rigney vs Jack Knott | Fifth | 20½ out |
| Friday, August 1 |
| » Lost to Senators (38-56), 8-2 | Griffith Stadium (4-3) | 47-52 | Lost 3 |
| » Starters: Thornton Lee vs Dutch Leonard | Fifth | 21½ out |
| Saturday, August 2 |
| » Defeated Senators (38-57), 3-1 | Griffith Stadium (5-3) | 48-52 | |
| » Starters: Eddie Smith vs Sid Hudson | Fifth | 21½ out |
| Sunday, August 3 |
| » Defeated Senators (38-58), 9-0 | Griffith Stadium (6-3) | 49-52 | Won 2 |
| » Starters: Ted Lyons vs Steve Sundra | Fifth | 20 out |
| Wednesday, August 6 |
| » Lost to Browns (41-59), 9-6 | Sportsman's Park III (3-1) | 49-53 | |
| » Starters: Johnny Rigney vs Elden Auker | Fourth | 20 out |
| » Defeated Browns (41-60), 5-2 | Sportsman's Park III (4-1) | 50-53 | |
| » Starters: Thornton Lee vs Bob Muncrief | Fourth | 20 out |
| Thursday, August 7 |
| » Defeated Browns (41-61), 11-1 | Sportsman's Park III (5-1) | 51-53 | Won 2 |
| » Starters: Buck Ross vs Denny Galehouse | Fourth | 19 out |
| Friday, August 8 |
| » Defeated Browns (41-62), 16-2 | Sportsman's Park III (6-1) | 52-53 | Won 3 |
| » Starters: Bill Dietrich vs Bob Harris | Fourth | 18 out |
| Saturday, August 9 |
| » Defeated Indians (58-46), 7-5 | League Park II (1-2) | 53-53 | Won 4 |
| » Starters: Eddie Smith vs Joe Krakauskas | Fourth | 18 out |
| Sunday, August 10 |
| » Defeated Indians (58-47), 5-2 | Cleveland Stadium (4-1) | 54-53 | Won 5 |
| » Starters: Ted Lyons vs Al Smith | Fourth | 18 out |
| » Defeated Indians (58-48), 2-1 | Cleveland Stadium (5-1) | 55-53 | Won 6 |
| » Starters: Thornton Lee vs Jim Bagby | Fourth | 18 out |
| Monday, August 11 |
| » Defeated Browns (42-64), 14-9 | Comiskey Park I (23-27) | 56-53 | Won 7 |
| » Starters: Elden Auker vs Johnny Rigney | Fourth | 17½ out |
| » Lost to Browns (43-64), 10-3 | Comiskey Park I (23-28) | 56-54 | |
| » Starters: George Caster vs Buck Ross | Fourth | 17½ out |
| Tuesday, August 12 |
| » Tied Browns, 6-6 | Comiskey Park I (23-28) | 56-54 | |
| » Starters: Bob Harris vs Bill Dietrich | Fourth | 18 out |
| Wednesday, August 13 |
| » Lost to Tigers (52-58), 4-1 | Comiskey Park I (23-29) | 56-55 | Lost 2 |
| » Starters: Bobo Newsom vs Eddie Smith | Fourth | 18½ out |
| Thursday, August 14 |
| » Defeated Tigers (52-59), 3-1 | Comiskey Park I (24-29) | 57-55 | |
| » Starters: Tommy Bridges vs Thornton Lee | Fourth | 18½ out |
| » Defeated Tigers (52-60), 3-0 | Comiskey Park I (25-29) | 58-55 | Won 2 |
| » Starters: Hal Newhouser vs Johnny Humphries | Fourth | 18½ out |
| Friday, August 15 |
| » Defeated Indians (59-51), 5-2 | Comiskey Park I (26-29) | 59-55 | Won 3 |
| » Starters: Al Smith vs Buck Ross | Fourth | 18 out |
| Saturday, August 16 |
| » Defeated Indians (59-52), 1-0 | Comiskey Park I (27-29) | 60-55 | Won 4 |
| » Starters: Jim Bagby vs Johnny Rigney | Fourth | 17 out |
| Sunday, August 17 |
| » Defeated Indians (59-53), 8-2 | Comiskey Park I (28-29) | 61-55 | Won 5 |
| » Starters: Bob Feller vs Ted Lyons | Second | 17 out |
| » Defeated Indians (59-54), 4-3 | Comiskey Park I (29-29) | 62-55 | Won 6 |
| » Starters: Al Milnar vs Eddie Smith | Second | 17 out |
| Monday, August 18 |
| » Major-league debuts: Steve Gromek (Indians) |
| Tuesday, August 19 |
| » Defeated Athletics (51-64), 4-0 | Comiskey Park I (30-29) | 63-55 | Won 7 |
| » Starters: Les McCrabb vs Thornton Lee | Second | 16 out |
| » Defeated Athletics (51-65), 1-0 | Comiskey Park I (31-29) | 64-55 | Won 8 |
| » Starters: Johnny Babich vs Johnny Humphries | Second | 16 out |
| Wednesday, August 20 |
| » Defeated Athletics (51-66), 9-0 | Comiskey Park I (32-29) | 65-55 | Won 9 |
| » Starters: Lum Harris vs Johnny Rigney | Second | 15 out |
| Thursday, August 21 |
| » Lost to Red Sox (62-58), 8-5 | Comiskey Park I (32-30) | 65-56 | |
| » Starters: Dick Newsome vs Eddie Smith | Second | 15 out |
| Friday, August 22 |
| » Lost to Red Sox (63-58), 2-1 | Comiskey Park I (32-31) | 65-57 | Lost 2 |
| » Starters: Joe Dobson vs Buck Ross | Second | 15 out |
| Saturday, August 23 |
| » Defeated Red Sox (63-59), 3-0 | Comiskey Park I (33-31) | 66-57 | |
| » Starters: Jack Wilson vs Johnny Humphries | Second | 15 out |
| Sunday, August 24 |
| » Lost to Yankees (83-43), 5-1 | Comiskey Park I (33-32) | 66-58 | |
| » Starters: Red Ruffing vs Ted Lyons | Second | 17 out |
| » Lost to Yankees (84-43), 8-5 | Comiskey Park I (33-33) | 66-59 | Lost 2 |
| » Starters: Spud Chandler vs Thornton Lee | Second | 17 out |
| Monday, August 25 |
| » Defeated Yankees (84-44), 9-1 | Comiskey Park I (34-33) | 67-59 | |
| » Starters: Marius Russo vs Eddie Smith | Second | 16 out |
| Wednesday, August 27 |
| » Lost to Senators (54-69), 11-3 | Comiskey Park I (34-34) | 67-60 | |
| » Starters: Ken Chase vs Johnny Rigney | Second | 17 out |
| Thursday, August 28 |
| » Defeated Senators (54-70), 4-0 | Comiskey Park I (35-34) | 68-60 | |
| » Starters: Steve Sundra vs Thornton Lee | Second | 17 out |
| Friday, August 29 |
| » Lost to Browns (55-71), 5-2 | Sportsman's Park III (6-2) | 68-61 | |
| » Starters: Buck Ross vs Elden Auker | Second | 17½ out |
| Saturday, August 30 |
| » Lost to Browns (56-71), 10-1 | Sportsman's Park III (6-3) | 68-62 | Lost 2 |
| » Starters: Johnny Humphries vs George Caster | Second | 18½ out |
| Sunday, August 31 |
| » Lost to Browns (57-71), 12-8 | Sportsman's Park III (6-4) | 68-63 | Lost 3 |
| » Starters: Ted Lyons vs Bob Muncrief | Second | 20 out |
| » Lost to Browns (58-71), 5-4 | Sportsman's Park III (6-5) | 68-64 | Lost 4 |
| » Starters: Eddie Smith vs Denny Galehouse | Second | 20 out |
| Monday, September 1 |
| » Defeated Indians (65-64), 7-5 | Cleveland Stadium (6-1) | 69-64 | |
| » Starters: Thornton Lee vs Jim Bagby | Second | 19 out |
| » Defeated Indians (65-65), 4-3 | Cleveland Stadium (7-1) | 70-64 | Won 2 |
| » Starters: Johnny Rigney vs Al Milnar | Second | 19 out |
| Tuesday, September 2 |
| Future White Sox Jerry Crider is born in Sioux Falls, SD. |
| Friday, September 5 |
| » Lost to Browns (59-73), 3-1 | Comiskey Park I (35-35) | 70-65 | |
| » Starters: Elden Auker vs Buck Ross | Second | 20½ out |
| Saturday, September 6 |
| » Lost to Browns (60-73), 3-0 | Comiskey Park I (35-36) | 70-66 | Lost 2 |
| » Starters: Bob Muncrief vs Thornton Lee | Second | 20 out |
| » Defeated Browns (60-74), 7-1 | Comiskey Park I (36-36) | 71-66 | |
| » Starters: George Caster vs Johnny Rigney | Second | 20 out |
| » Major-league debuts: Dave Philley (White Sox) |
| Sunday, September 7 |
| » Lost to Browns (61-74), 3-1 | Comiskey Park I (36-37) | 71-67 | |
| » Starters: Denny Galehouse vs Ted Lyons | Second | 21 out |
| Tuesday, September 9 |
| » Lost to Senators (59-75), 7-2 | Griffith Stadium (6-4) | 71-68 | Lost 2 |
| » Starters: Eddie Smith vs Red Anderson | Third | 22 out |
| Wednesday, September 10 |
| » Defeated Senators (59-76), 12-4 | Griffith Stadium (7-4) | 72-68 | |
| » Starters: Thornton Lee vs Sid Hudson | Third | 21½ out |
| Thursday, September 11 |
| » Lost to Athletics (61-78), 2-1 | Shibe Park (3-6) | 72-69 | |
| » Starters: Johnny Rigney vs Herman Besse | Third | 21½ out |
| Friday, September 12 |
| » Defeated Athletics (61-79), 2-0 | Shibe Park (4-6) | 73-69 | |
| » Starters: Johnny Humphries vs Phil Marchildon | Third | 21½ out |
| Saturday, September 13 |
| » Lost to Athletics (62-79), 3-1 | Shibe Park (4-7) | 73-70 | |
| » Starters: Eddie Smith vs Dick Fowler | Third | 21½ out |
| Sunday, September 14 |
| » Lost to Red Sox (75-67), 9-2 | Fenway Park (3-6) | 73-71 | Lost 2 |
| » Starters: Ted Lyons vs Dick Newsome | Third | 22½ out |
| » Lost to Red Sox (76-67), 5-1 | Fenway Park (3-7) | 73-72 | Lost 3 |
| » Starters: Thornton Lee vs Charlie Wagner | Third | 22½ out |
| Monday, September 15 |
| » Lost to Red Sox (77-67), 6-1 | Fenway Park (3-8) | 73-73 | Lost 4 |
| » Starters: Johnny Rigney vs Mickey Harris | Third | 23½ out |
| Tuesday, September 16 |
| » Major-league debuts: Hillis Layne (Senators) Hoot Evers (Tigers) |
| Wednesday, September 17 |
| » Lost to Yankees (97-49), 5-3 | Yankee Stadium (5-6) | 73-74 | Lost 5 |
| » Starters: Eddie Smith vs Spud Chandler | Third | 24½ out |
| Saturday, September 20 |
| » Defeated Tigers (71-76), 4-3 | Comiskey Park I (37-37) | 74-74 | |
| » Starters: Bobo Newsom vs Thornton Lee | Third | 24½ out |
| » Major-league debuts: Jake Jones (White Sox) |
| Future White Sox Dennis Ribant is born in Detroit, MI. |
| Sunday, September 21 |
| » Lost to Tigers (72-76), 6-3 | Comiskey Park I (37-38) | 74-75 | |
| » Starters: Tommy Bridges vs Ted Lyons | Third | 24½ out |
| » Tied Tigers, 1-1 | Comiskey Park I (37-38) | 74-75 | |
| » Starters: Schoolboy Rowe vs Johnny Rigney | Third | 24½ out |
| Monday, September 22 |
| » Lost to Tigers (73-76), 11-0 | Comiskey Park I (37-39) | 74-76 | Lost 2 |
| » Starters: Al Benton vs Bill Dietrich | Third | 25 out |
| Wednesday, September 24 |
| » Defeated Indians (73-77), 2-1 | Comiskey Park I (38-39) | 75-76 | |
| » Starters: Jim Bagby vs Thornton Lee | Third | 24½ out |
| Friday, September 26 |
| » Lost to Tigers (75-77), 4-3 | Tiger Stadium (4-5) | 75-77 | |
| » Starters: Eddie Smith vs Al Benton | Third | 26 out |
| Saturday, September 27 |
| » Defeated Tigers (75-78), 10-6 | Tiger Stadium (5-5) | 76-77 | |
| » Starters: Johnny Rigney vs Schoolboy Rowe | Third | 25 out |
| » Major-league debuts: Virgil Trucks (Tigers) |
| Sunday, September 28 |
| » Defeated Tigers (75-79), 3-0 | Tiger Stadium (6-5) | 77-77 | Won 2 |
| » Starters: Thornton Lee vs Tommy Bridges | Third | 24 out |
| Wednesday, October 22 |
| Future White Sox Wilbur Wood is born in Cambridge, MA. |
| Friday, October 31 |
| Future White Sox Ed Spiezio is born in Joliet, IL. |
| Saturday, November 29 |
| Former White Sox Ed Hahn dies in Des Moines, IA at the age of 67. |
Game information provided by Retrosheet (www.retrosheet.org) |
