| Monday, April 14 |
| » Major-league debuts: Phil Rizzuto and Johnny Sturm (Yankees) |
| Tuesday, April 15 |
| » Defeated Senators (0-2), 7-6 | Fenway Park (1-0) | 1-0 | |
| » Starters: Sid Hudson vs Jack Wilson | First | -- |
| Wednesday, April 16 |
| » Defeated Senators (0-3), 8-7 | Fenway Park (2-0) | 2-0 | Won 2 |
| » Starters: Walt Masterson vs Charlie Wagner | First | -- |
| » Major-league debuts: Tex Hughson and Oscar Judd (Red Sox) |
| Thursday, April 17 |
| » Major-league debuts: Gerry Priddy (Yankees) Rankin Johnson (Athletics) |
| Friday, April 18 |
| » Defeated Athletics (2-2), 3-2 | Shibe Park (1-0) | 3-0 | Won 3 |
| » Starters: Lefty Grove vs Jack Knott | First | -- |
| Saturday, April 19 |
| » Defeated Athletics (2-3), 7-2 | Shibe Park (2-0) | 4-0 | Won 4 |
| » Starters: Emerson Dickman vs Bill Beckmann | First | -- |
| Sunday, April 20 |
| » Defeated Senators (1-5), 14-8 | Griffith Stadium (1-0) | 5-0 | Won 5 |
| » Starters: Mike Ryba vs Sid Hudson | First | -- |
| Monday, April 21 |
| » Lost to Senators (2-5), 6-5 | Griffith Stadium (1-1) | 5-1 | |
| » Starters: Jack Wilson vs Steve Sundra | First | -- |
| Tuesday, April 22 |
| » Lost to Senators (3-5), 12-5 | Griffith Stadium (1-2) | 5-2 | Lost 2 |
| » Starters: Mickey Harris vs Walt Masterson | First | -- |
| Wednesday, April 23 |
| » Lost to Yankees (6-4), 4-2 | Yankee Stadium (0-1) | 5-3 | Lost 3 |
| » Starters: Charlie Wagner vs Lefty Gomez | First | -- |
| Thursday, April 24 |
| » Lost to Yankees (7-4), 6-3 | Yankee Stadium (0-2) | 5-4 | Lost 4 |
| » Starters: Emerson Dickman vs Marius Russo | Third | 1 out |
| Friday, April 25 |
| » Defeated Athletics (4-6), 3-1 | Fenway Park (3-0) | 6-4 | |
| » Starters: Jack Knott vs Dick Newsome | Second | 1 out |
| » Major-league debuts: Dick Newsome (Red Sox) |
| Saturday, April 26 |
| » Defeated Athletics (4-7), 8-7 | Fenway Park (4-0) | 7-4 | Won 2 |
| » Starters: Bill Beckmann vs Woody Rich | Second | 1 out |
| Tuesday, April 29 |
| » Lost to Tigers (5-7), 5-3 | Tiger Stadium (0-1) | 7-5 | |
| » Starters: Lefty Grove vs Johnny Gorsica | Fourth | 2 out |
| Wednesday, April 30 |
| » Lost to Tigers (6-7), 12-8 | Tiger Stadium (0-2) | 7-6 | Lost 2 |
| » Starters: Charlie Wagner vs Bobo Newsom | Fourth | 3 out |
| Thursday, May 1 |
| » Defeated Tigers (6-8), 15-9 | Tiger Stadium (1-2) | 8-6 | |
| » Starters: Earl Johnson vs Tommy Bridges | Fourth | 3 out |
| Friday, May 2 |
| » Lost to Indians (13-4), 7-3 | League Park II (0-1) | 8-7 | |
| » Starters: Dick Newsome vs Mel Harder | Fourth | 4 out |
| Saturday, May 3 |
| » Lost to Indians (14-4), 4-2 | League Park II (0-2) | 8-8 | Lost 2 |
| » Starters: Mike Ryba vs Al Milnar | Fourth | 5 out |
| Sunday, May 4 |
| » Defeated Browns (4-11), 11-4 | Sportsman's Park III (1-0) | 9-8 | |
| » Starters: Lefty Grove vs Bob Harris | Fourth | 5 out |
| Monday, May 5 |
| Future Red Sox Tommy Helms is born in Charlotte, NC. |
| Wednesday, May 7 |
| » Defeated White Sox (10-9), 4-3 | Comiskey Park I (1-0) | 10-8 | Won 2 |
| » Starters: Charlie Wagner vs Johnny Rigney | Third | 4 out |
| Sunday, May 11 |
| » Defeated Yankees (14-11), 13-5 | Fenway Park (5-0) | 11-8 | Won 3 |
| » Starters: Spud Chandler vs Earl Johnson | Second | 4 out |
| Monday, May 12 |
| » Defeated Yankees (14-12), 8-4 | Fenway Park (6-0) | 12-8 | Won 4 |
| » Starters: Lefty Gomez vs Lefty Grove | Second | 3½ out |
| Tuesday, May 13 |
| » Lost to White Sox (13-9), 3-2 | Fenway Park (6-1) | 12-9 | |
| » Starters: Johnny Rigney vs Charlie Wagner | Third | 3½ out |
| Wednesday, May 14 |
| » Defeated White Sox (13-10), 10-7 | Fenway Park (7-1) | 13-9 | |
| » Starters: Bill Dietrich vs Emerson Dickman | Second | 3½ out |
| Thursday, May 15 |
| » Lost to Indians (21-9), 6-4 | Fenway Park (7-2) | 13-10 | |
| » Starters: Al Milnar vs Earl Johnson | Third | 4½ out |
| Friday, May 16 |
| » Lost to Indians (22-9), 9-3 | Fenway Park (7-3) | 13-11 | Lost 2 |
| » Starters: Jim Bagby vs Mickey Harris | Third | 5½ out |
| Saturday, May 17 |
| » Lost to Indians (23-9), 12-9 | Fenway Park (7-4) | 13-12 | Lost 3 |
| » Starters: Bob Feller vs Charlie Wagner | Third | 6½ out |
| Sunday, May 18 |
| » Lost to Tigers (15-14), 6-5 | Fenway Park (7-5) | 13-13 | Lost 4 |
| » Starters: Bobo Newsom vs Lefty Grove | Fourth | 6½ out |
| Monday, May 19 |
| » Lost to Tigers (16-14), 4-2 | Fenway Park (7-6) | 13-14 | Lost 5 |
| » Starters: Johnny Gorsica vs Joe Dobson | Fifth | 6½ out |
| Tuesday, May 20 |
| » Defeated Tigers (16-15), 4-2 | Fenway Park (8-6) | 14-14 | |
| » Starters: Hal Newhouser vs Earl Johnson | Fourth | 5½ out |
| Wednesday, May 21 |
| » Defeated Browns (10-20), 8-6 | Fenway Park (9-6) | 15-14 | Won 2 |
| » Starters: Johnny Allen vs Mike Ryba | Third | 5½ out |
| Thursday, May 22 |
| » Lost to Browns (11-20), 4-1 | Fenway Park (9-7) | 15-15 | |
| » Starters: Bob Muncrief vs Charlie Wagner | Fourth | 6½ out |
| Friday, May 23 |
| » Tied Yankees, 9-9 | Yankee Stadium (0-2) | 15-15 | |
| » Starters: Joe Dobson vs Spud Chandler | Fourth | 7 out |
| Saturday, May 24 |
| » Lost to Yankees (20-17), 7-6 | Yankee Stadium (0-3) | 15-16 | Lost 2 |
| » Starters: Earl Johnson vs Lefty Gomez | Fifth | 8 out |
| Sunday, May 25 |
| » Defeated Yankees (20-18), 10-3 | Yankee Stadium (1-3) | 16-16 | |
| » Starters: Lefty Grove vs Marius Russo | Fourth | 8 out |
| Tuesday, May 27 |
| » Defeated Athletics (17-20), 5-2 | Fenway Park (10-7) | 17-16 | Won 2 |
| » Starters: Bump Hadley vs Charlie Wagner | Fifth | 7 out |
| » Lost to Athletics (18-20), 11-1 | Fenway Park (10-8) | 17-17 | |
| » Starters: Phil Marchildon vs Dick Newsome | Fifth | 7 out |
| Wednesday, May 28 |
| » Lost to Athletics (19-20), 8-6 | Fenway Park (10-9) | 17-18 | Lost 2 |
| » Starters: Bill Beckmann vs Bill Fleming | Sixth | 7 out |
| Thursday, May 29 |
| » Defeated Athletics (19-21), 6-4 | Fenway Park (11-9) | 18-18 | |
| » Starters: Jack Knott vs Joe Dobson | Fifth | 7 out |
| Friday, May 30 |
| » Lost to Yankees (23-18), 4-3 | Fenway Park (11-10) | 18-19 | |
| » Starters: Atley Donald vs Earl Johnson | Fifth | 6 out |
| » Defeated Yankees (23-19), 13-0 | Fenway Park (12-10) | 19-19 | |
| » Starters: Charley Stanceu vs Mickey Harris | Fifth | 6 out |
| Sunday, June 1 |
| » Defeated Tigers (23-21), 7-6 | Tiger Stadium (2-2) | 20-19 | Won 2 |
| » Starters: Lefty Grove vs Johnny Gorsica | Fourth | 3½ out |
| » Defeated Tigers (23-22), 6-5 | Tiger Stadium (3-2) | 21-19 | Won 3 |
| » Starters: Charlie Wagner vs Schoolboy Rowe | Fourth | 3½ out |
| Monday, June 2 |
| » Defeated Tigers (23-23), 9-1 | Tiger Stadium (4-2) | 22-19 | Won 4 |
| » Starters: Joe Dobson vs Bobo Newsom | Fourth | 4 out |
| Thursday, June 5 |
| » Defeated Indians (30-20), 14-1 | League Park II (1-2) | 23-19 | Won 5 |
| » Starters: Mickey Harris vs Al Milnar | Third | 4 out |
| Friday, June 6 |
| » Defeated White Sox (27-20), 6-3 | Comiskey Park I (2-0) | 24-19 | Won 6 |
| » Starters: Joe Dobson vs Johnny Rigney | Third | 4 out |
| Saturday, June 7 |
| » Lost to White Sox (28-20), 5-4 | Comiskey Park I (2-1) | 24-20 | |
| » Starters: Jack Wilson vs Eddie Smith | Third | 4 out |
| Sunday, June 8 |
| » Defeated White Sox (28-21), 5-3 | Comiskey Park I (3-1) | 25-20 | |
| » Starters: Lefty Grove vs Ted Lyons | Second | 4 out |
| » Defeated White Sox (28-22), 3-0 | Comiskey Park I (4-1) | 26-20 | Won 2 |
| » Starters: Dick Newsome vs Thornton Lee | Second | 4 out |
| Thursday, June 12 |
| » Lost to Browns (17-32), 9-4 | Sportsman's Park III (1-1) | 26-21 | |
| » Starters: Joe Dobson vs Bob Harris | Third | 5 out |
| » Defeated Browns (17-33), 3-2 | Sportsman's Park III (2-1) | 27-21 | |
| » Starters: Earl Johnson vs Johnny Niggeling | Third | 5 out |
| Saturday, June 14 |
| » Lost to White Sox (29-24), 5-2 | Fenway Park (12-11) | 27-22 | |
| » Starters: Eddie Smith vs Mickey Harris | Third | 5 out |
| Sunday, June 15 |
| » Defeated White Sox (29-25), 8-6 | Fenway Park (13-11) | 28-22 | |
| » Starters: Ted Lyons vs Lefty Grove | Third | 3½ out |
| » Defeated White Sox (29-26), 6-4 | Fenway Park (14-11) | 29-22 | Won 2 |
| » Starters: Buck Ross vs Dick Newsome | Third | 3½ out |
| Tuesday, June 17 |
| » Defeated Tigers (30-28), 14-6 | Fenway Park (15-11) | 30-22 | Won 3 |
| » Starters: Floyd Giebell vs Joe Dobson | Third | 3½ out |
| » Lost to Tigers (31-28), 8-5 | Fenway Park (15-12) | 30-23 | |
| » Starters: Johnny Gorsica vs Charlie Wagner | Third | 3½ out |
| Wednesday, June 18 |
| » Lost to Tigers (32-28), 5-2 | Fenway Park (15-13) | 30-24 | Lost 2 |
| » Starters: Schoolboy Rowe vs Mickey Harris | Third | 4½ out |
| Thursday, June 19 |
| » Defeated Tigers (32-29), 6-4 | Fenway Park (16-13) | 31-24 | |
| » Starters: Tommy Bridges vs Dick Newsome | Third | 4½ out |
| Friday, June 20 |
| » Defeated Browns (19-36), 4-2 | Fenway Park (17-13) | 32-24 | Won 2 |
| » Starters: Elden Auker vs Joe Dobson | Third | 3½ out |
| Saturday, June 21 |
| » Lost to Browns (20-36), 13-9 | Fenway Park (17-14) | 32-25 | |
| » Starters: Bob Harris vs Lefty Grove | Third | 3½ out |
| Sunday, June 22 |
| » Defeated Browns (20-37), 7-5 | Fenway Park (18-14) | 33-25 | |
| » Starters: Jack Kramer vs Charlie Wagner | Third | 4 out |
| » Lost to Browns (21-37), 12-3 | Fenway Park (18-15) | 33-26 | |
| » Starters: Johnny Niggeling vs Mickey Harris | Third | 4 out |
| Tuesday, June 24 |
| » Defeated Indians (40-26), 13-2 | Fenway Park (19-15) | 34-26 | |
| » Starters: Mel Harder vs Dick Newsome | Third | 3 out |
| Wednesday, June 25 |
| » Defeated Indians (40-27), 7-2 | Fenway Park (20-15) | 35-26 | Won 2 |
| » Starters: Jim Bagby vs Lefty Grove | Third | 2 out |
| Thursday, June 26 |
| » Lost to Indians (41-27), 11-8 | Fenway Park (20-16) | 35-27 | |
| » Starters: Bob Feller vs Mickey Harris | Third | 3 out |
| Friday, June 27 |
| » Lost to Senators (25-40), 5-3 | Griffith Stadium (1-3) | 35-28 | Lost 2 |
| » Starters: Jack Wilson vs Steve Sundra | Third | 4 out |
| Saturday, June 28 |
| » Lost to Senators (26-40), 3-1 | Griffith Stadium (1-4) | 35-29 | Lost 3 |
| » Starters: Dick Newsome vs Bill Zuber | Third | 4 out |
| Sunday, June 29 |
| » Defeated Athletics (31-36), 13-1 | Shibe Park (3-0) | 36-29 | |
| » Starters: Charlie Wagner vs Les McCrabb | Third | 5 out |
| » Lost to Athletics (32-36), 3-2 | Shibe Park (3-1) | 36-30 | |
| » Starters: Joe Dobson vs Jack Knott | Third | 5 out |
| Tuesday, July 1 |
| » Lost to Yankees (43-26), 7-2 | Yankee Stadium (1-4) | 36-31 | Lost 2 |
| » Starters: Mickey Harris vs Marius Russo | Third | 7 out |
| » Lost to Yankees (44-26), 9-2 | Yankee Stadium (1-5) | 36-32 | Lost 3 |
| » Starters: Jack Wilson vs Tiny Bonham | Third | 7 out |
| Wednesday, July 2 |
| » Lost to Yankees (45-26), 8-4 | Yankee Stadium (1-6) | 36-33 | Lost 4 |
| » Starters: Dick Newsome vs Lefty Gomez | Third | 8 out |
| Thursday, July 3 |
| » Defeated Athletics (34-37), 5-2 | Shibe Park (4-1) | 37-33 | |
| » Starters: Lefty Grove vs Chubby Dean | Third | 7½ out |
| Saturday, July 5 |
| » Defeated Senators (26-45), 5-0 | Fenway Park (21-16) | 38-33 | Won 2 |
| » Starters: Dutch Leonard vs Charlie Wagner | Third | 7½ out |
| Sunday, July 6 |
| » Defeated Senators (26-46), 6-2 | Fenway Park (22-16) | 39-33 | Won 3 |
| » Starters: Ken Chase vs Dick Newsome | Third | 7½ out |
| » Defeated Senators (26-47), 4-3 | Fenway Park (23-16) | 40-33 | Won 4 |
| » Starters: Bill Zuber vs Tex Hughson | Third | 7½ out |
| Tuesday, July 8 |
| Future Red Sox Ken Sanders is born in St. Louis, MO. |
| Friday, July 11 |
| » Lost to Tigers (40-40), 2-0 | Tiger Stadium (4-3) | 40-34 | |
| » Starters: Lefty Grove vs Bobo Newsom | Third | 9 out |
| Saturday, July 12 |
| » Defeated Tigers (40-41), 7-5 | Tiger Stadium (5-3) | 41-34 | |
| » Starters: Dick Newsome vs Johnny Gorsica | Third | 8½ out |
| » Defeated Tigers (40-42), 10-2 | Tiger Stadium (6-3) | 42-34 | Won 2 |
| » Starters: Tex Hughson vs Dizzy Trout | Third | 8½ out |
| Sunday, July 13 |
| » Lost to Indians (48-32), 9-6 | Cleveland Stadium (0-1) | 42-35 | |
| » Starters: Charlie Wagner vs Jim Bagby | Third | 10½ out |
| » Lost to Indians (49-32), 2-1 | Cleveland Stadium (0-2) | 42-36 | Lost 2 |
| » Starters: Mickey Harris vs Al Smith | Third | 10½ out |
| Monday, July 14 |
| » Lost to Indians (50-32), 4-1 | League Park II (1-3) | 42-37 | Lost 3 |
| » Starters: Jack Wilson vs Bob Feller | Third | 10½ out |
| Tuesday, July 15 |
| » Defeated Indians (50-33), 6-2 | League Park II (2-3) | 43-37 | |
| » Starters: Joe Dobson vs Mel Harder | Third | 10½ out |
| Wednesday, July 16 |
| » Defeated White Sox (41-41), 2-1 | Comiskey Park I (5-1) | 44-37 | Won 2 |
| » Starters: Tex Hughson vs Buck Ross | Third | 10½ out |
| Thursday, July 17 |
| » Defeated White Sox (41-42), 7-4 | Comiskey Park I (6-1) | 45-37 | Won 3 |
| » Starters: Dick Newsome vs Thornton Lee | Third | 10½ out |
| Friday, July 18 |
| » Lost to White Sox (42-42), 4-3 | Comiskey Park I (6-2) | 45-38 | |
| » Starters: Lefty Grove vs Johnny Rigney | Third | 10½ out |
| Saturday, July 19 |
| » Lost to Browns (31-51), 9-3 | Sportsman's Park III (2-2) | 45-39 | Lost 2 |
| » Starters: Charlie Wagner vs Johnny Allen | Third | 12½ out |
| » Lost to Browns (32-51), 4-3 | Sportsman's Park III (2-3) | 45-40 | Lost 3 |
| » Starters: Mickey Harris vs Elden Auker | Third | 12½ out |
| Sunday, July 20 |
| » Lost to Browns (33-51), 6-3 | Sportsman's Park III (2-4) | 45-41 | Lost 4 |
| » Starters: Tex Hughson vs Johnny Niggeling | Third | 14 out |
| » Lost to Browns (34-51), 10-0 | Sportsman's Park III (2-5) | 45-42 | Lost 5 |
| » Starters: Joe Dobson vs Bob Muncrief | Third | 14 out |
| Monday, July 21 |
| Future Red Sox Gary Waslewski is born in Meriden, CT. |
| Tuesday, July 22 |
| » Defeated White Sox (44-45), 6-2 | Fenway Park (24-16) | 46-42 | |
| » Starters: Johnny Rigney vs Dick Newsome | Third | 14 out |
| Wednesday, July 23 |
| » Lost to White Sox (45-45), 10-4 | Fenway Park (24-17) | 46-43 | |
| » Starters: Thornton Lee vs Tex Hughson | Third | 15 out |
| Thursday, July 24 |
| » Defeated White Sox (45-46), 11-1 | Fenway Park (25-17) | 47-43 | |
| » Starters: Bill Dietrich vs Mickey Harris | Third | 15 out |
| Friday, July 25 |
| » Defeated Indians (53-40), 10-6 | Fenway Park (26-17) | 48-43 | Won 2 |
| » Starters: Joe Krakauskas vs Lefty Grove | Third | 15 out |
| Saturday, July 26 |
| » Defeated Indians (53-41), 4-3 | Fenway Park (27-17) | 49-43 | Won 3 |
| » Starters: Bob Feller vs Dick Newsome | Third | 15 out |
| Sunday, July 27 |
| » Lost to Indians (54-41), 4-0 | Fenway Park (27-18) | 49-44 | |
| » Starters: Joe Heving vs Tex Hughson | Third | 15½ out |
| Tuesday, July 29 |
| » Lost to Browns (37-56), 3-2 | Fenway Park (27-19) | 49-45 | Lost 2 |
| » Starters: Johnny Niggeling vs Mickey Harris | Third | 15½ out |
| Wednesday, July 30 |
| Former Red Sox Howard Shanks dies in Monaca, PA at the age of 52. |
| Thursday, July 31 |
| » Lost to Browns (38-56), 16-11 | Fenway Park (27-20) | 49-46 | Lost 3 |
| » Starters: Bob Harris vs Dick Newsome | Third | 16½ out |
| » Defeated Browns (38-57), 4-1 | Fenway Park (28-20) | 50-46 | |
| » Starters: Bob Muncrief vs Tex Hughson | Third | 16½ out |
| Saturday, August 2 |
| » Lost to Tigers (46-55), 6-5 | Fenway Park (28-21) | 50-47 | |
| » Starters: Dizzy Trout vs Lefty Grove | Third | 18 out |
| Sunday, August 3 |
| » Lost to Tigers (47-55), 6-3 | Fenway Park (28-22) | 50-48 | Lost 2 |
| » Starters: Hal Newhouser vs Dick Newsome | Third | 17½ out |
| Monday, August 4 |
| » Defeated Athletics (48-52), 7-6 | Fenway Park (29-22) | 51-48 | |
| » Starters: Lum Harris vs Mickey Harris | Third | 17½ out |
| Tuesday, August 5 |
| » Defeated Athletics (48-53), 6-5 | Fenway Park (30-22) | 52-48 | Won 2 |
| » Starters: Jack Knott vs Joe Dobson | Third | 16½ out |
| Wednesday, August 6 |
| » Defeated Yankees (70-34), 6-3 | Fenway Park (31-22) | 53-48 | Won 3 |
| » Starters: Spud Chandler vs Tex Hughson | Third | 16½ out |
| » Lost to Yankees (71-34), 3-1 | Fenway Park (31-23) | 53-49 | |
| » Starters: Marv Breuer vs Mickey Harris | Third | 16½ out |
| Thursday, August 7 |
| » Defeated Yankees (71-35), 9-5 | Fenway Park (32-23) | 54-49 | |
| » Starters: Lefty Gomez vs Dick Newsome | Third | 15½ out |
| Friday, August 8 |
| » Defeated Senators (41-60), 15-8 | Fenway Park (33-23) | 55-49 | Won 2 |
| » Starters: Steve Sundra vs Charlie Wagner | Third | 14½ out |
| Saturday, August 9 |
| » Lost to Senators (42-60), 8-6 | Fenway Park (33-24) | 55-50 | |
| » Starters: Ken Chase vs Lefty Grove | Third | 15½ out |
| Sunday, August 10 |
| » Defeated Senators (42-61), 7-6 | Fenway Park (34-24) | 56-50 | |
| » Starters: Steve Sundra vs Earl Johnson | Third | 16½ out |
| » Lost to Senators (43-61), 8-2 | Fenway Park (34-25) | 56-51 | |
| » Starters: Alex Carrasquel vs Mickey Harris | Third | 16½ out |
| Monday, August 11 |
| » Defeated Yankees (74-37), 8-0 | Yankee Stadium (2-6) | 57-51 | |
| » Starters: Jack Wilson vs Marv Breuer | Third | 15½ out |
| Tuesday, August 12 |
| » Lost to Yankees (75-37), 4-0 | Yankee Stadium (2-7) | 57-52 | |
| » Starters: Dick Newsome vs Spud Chandler | Third | 16½ out |
| Wednesday, August 13 |
| » Defeated Athletics (49-60), 4-0 | Shibe Park (5-1) | 58-52 | |
| » Starters: Charlie Wagner vs Phil Marchildon | Third | 16 out |
| Thursday, August 14 |
| » Defeated Athletics (49-61), 11-8 | Shibe Park (6-1) | 59-52 | Won 2 |
| » Starters: Mickey Harris vs Tom Ferrick | Third | 17 out |
| » Lost to Athletics (50-61), 10-8 | Shibe Park (6-2) | 59-53 | |
| » Starters: Jack Wilson vs Lum Harris | Third | 17 out |
| Friday, August 15 |
| » Senators forfeited to Red Sox. | Griffith Stadium (2-4) | 60-53 | |
| » Starters: Earl Johnson vs Alex Carrasquel | Third | 17½ out |
| Saturday, August 16 |
| » Defeated Senators (46-65), 8-6 | Griffith Stadium (3-4) | 61-53 | Won 2 |
| » Starters: Lefty Grove vs Dutch Leonard | Third | 16½ out |
| Sunday, August 17 |
| » Lost to Senators (47-65), 6-2 | Griffith Stadium (3-5) | 61-54 | |
| » Starters: Dick Newsome vs Sid Hudson | Third | 18 out |
| Monday, August 18 |
| » Major-league debuts: Steve Gromek (Indians) |
| Tuesday, August 19 |
| » Lost to Browns (48-65), 3-2 | Sportsman's Park III (2-6) | 61-55 | Lost 2 |
| » Starters: Jack Wilson vs Denny Galehouse | Third | 18 out |
| » Defeated Browns (48-66), 10-7 | Sportsman's Park III (3-6) | 62-55 | |
| » Starters: Earl Johnson vs Bob Muncrief | Third | 18 out |
| Wednesday, August 20 |
| » Lost to Browns (49-66), 11-9 | Sportsman's Park III (3-7) | 62-56 | |
| » Starters: Lefty Grove vs Elden Auker | Third | 18½ out |
| » Lost to Browns (50-66), 4-3 | Sportsman's Park III (3-8) | 62-57 | Lost 2 |
| » Starters: Charlie Wagner vs Johnny Niggeling | Third | 18½ out |
| Thursday, August 21 |
| » Defeated White Sox (65-56), 8-5 | Comiskey Park I (7-2) | 63-57 | |
| » Starters: Dick Newsome vs Eddie Smith | Third | 17½ out |
| Friday, August 22 |
| » Defeated White Sox (65-57), 2-1 | Comiskey Park I (8-2) | 64-57 | Won 2 |
| » Starters: Joe Dobson vs Buck Ross | Third | 16½ out |
| Saturday, August 23 |
| » Lost to White Sox (66-57), 3-0 | Comiskey Park I (8-3) | 64-58 | |
| » Starters: Jack Wilson vs Johnny Humphries | Third | 17½ out |
| Sunday, August 24 |
| » Lost to Indians (62-58), 4-3 | Cleveland Stadium (0-3) | 64-59 | Lost 2 |
| » Starters: Mickey Harris vs Al Milnar | Fourth | 19½ out |
| » Lost to Indians (63-58), 5-2 | Cleveland Stadium (0-4) | 64-60 | Lost 3 |
| » Starters: Earl Johnson vs Al Smith | Fourth | 19½ out |
| Monday, August 25 |
| » Defeated Indians (63-59), 1-0 | Cleveland Stadium (1-4) | 65-60 | |
| » Starters: Charlie Wagner vs Bob Feller | Fourth | 18½ out |
| Tuesday, August 26 |
| » Defeated Indians (63-60), 9-4 | League Park II (3-3) | 66-60 | Won 2 |
| » Starters: Dick Newsome vs Jim Bagby | Third | 18 out |
| Wednesday, August 27 |
| » Lost to Tigers (59-68), 6-3 | Tiger Stadium (6-4) | 66-61 | |
| » Starters: Lefty Grove vs Hal Newhouser | Fourth | 19 out |
| Thursday, August 28 |
| » Lost to Tigers (60-68), 8-7 | Tiger Stadium (6-5) | 66-62 | Lost 2 |
| » Starters: Joe Dobson vs Al Benton | Fourth | 20 out |
| Saturday, August 30 |
| » Defeated Athletics (56-71), 12-3 | Fenway Park (35-25) | 67-62 | |
| » Starters: Les McCrabb vs Charlie Wagner | Third | 20 out |
| Sunday, August 31 |
| » Defeated Athletics (56-72), 5-3 | Fenway Park (36-25) | 68-62 | Won 2 |
| » Starters: Jack Knott vs Dick Newsome | Third | 20½ out |
| » Lost to Athletics (57-72), 3-2 | Fenway Park (36-26) | 68-63 | |
| » Starters: Phil Marchildon vs Earl Johnson | Third | 20½ out |
| Monday, September 1 |
| » Defeated Senators (54-73), 13-9 | Fenway Park (37-26) | 69-63 | |
| » Starters: Alex Carrasquel vs Mickey Harris | Third | 19½ out |
| » Defeated Senators (54-74), 10-2 | Fenway Park (38-26) | 70-63 | Won 2 |
| » Starters: Red Anderson vs Joe Dobson | Third | 19½ out |
| Wednesday, September 3 |
| » Lost to Yankees (90-45), 2-1 | Fenway Park (38-27) | 70-64 | |
| » Starters: Tiny Bonham vs Charlie Wagner | Third | 20½ out |
| Thursday, September 4 |
| » Lost to Yankees (91-45), 6-3 | Fenway Park (38-28) | 70-65 | Lost 2 |
| » Starters: Atley Donald vs Dick Newsome | Third | 21½ out |
| Future Red Sox Ken Harrelson is born in Woodruff, SC. |
| Saturday, September 6 |
| » Defeated Yankees (91-46), 8-1 | Yankee Stadium (3-7) | 71-65 | |
| » Starters: Joe Dobson vs Marv Breuer | Third | 20½ out |
| Sunday, September 7 |
| » Lost to Yankees (92-46), 8-5 | Yankee Stadium (3-8) | 71-66 | |
| » Starters: Jack Wilson vs Lefty Gomez | Third | 21½ out |
| Tuesday, September 9 |
| » Defeated Tigers (67-71), 6-0 | Fenway Park (39-28) | 72-66 | |
| » Starters: Johnny Gorsica vs Dick Newsome | Second | 21½ out |
| Wednesday, September 10 |
| » Defeated Tigers (67-72), 11-2 | Fenway Park (40-28) | 73-66 | Won 2 |
| » Starters: Bobo Newsom vs Charlie Wagner | Second | 21 out |
| Friday, September 12 |
| » Defeated Browns (61-76), 5-0 | Fenway Park (41-28) | 74-66 | Won 3 |
| » Starters: Johnny Niggeling vs Joe Dobson | Second | 20½ out |
| Saturday, September 13 |
| » Defeated Browns (61-77), 7-2 | Fenway Park (42-28) | 75-66 | Won 4 |
| » Starters: Elden Auker vs Jack Wilson | Second | 19½ out |
| Sunday, September 14 |
| » Defeated White Sox (73-71), 9-2 | Fenway Park (43-28) | 76-66 | Won 5 |
| » Starters: Ted Lyons vs Dick Newsome | Second | 18½ out |
| » Defeated White Sox (73-72), 5-1 | Fenway Park (44-28) | 77-66 | Won 6 |
| » Starters: Thornton Lee vs Charlie Wagner | Second | 18½ out |
| Monday, September 15 |
| » Defeated White Sox (73-73), 6-1 | Fenway Park (45-28) | 78-66 | Won 7 |
| » Starters: Johnny Rigney vs Mickey Harris | Second | 18½ out |
| Tuesday, September 16 |
| » Major-league debuts: Hillis Layne (Senators) Hoot Evers (Tigers) |
| Wednesday, September 17 |
| » Defeated Indians (70-74), 3-2 | Fenway Park (46-28) | 79-66 | Won 8 |
| » Starters: Jim Bagby vs Joe Dobson | Second | 18½ out |
| Thursday, September 18 |
| » Lost to Indians (71-74), 6-1 | Fenway Park (46-29) | 79-67 | |
| » Starters: Bob Feller vs Dick Newsome | Second | 19 out |
| Saturday, September 20 |
| » Lost to Yankees (98-49), 8-1 | Fenway Park (46-30) | 79-68 | Lost 2 |
| » Starters: Marius Russo vs Charlie Wagner | Second | 20 out |
| Sunday, September 21 |
| » Defeated Yankees (98-50), 4-1 | Fenway Park (47-30) | 80-68 | |
| » Starters: Tiny Bonham vs Mickey Harris | Second | 19 out |
| Tuesday, September 23 |
| » Lost to Senators (69-79), 4-3 | Griffith Stadium (3-6) | 80-69 | |
| » Starters: Dick Newsome vs Sid Hudson | Second | 19 out |
| Wednesday, September 24 |
| » Defeated Senators (69-80), 7-2 | Griffith Stadium (4-6) | 81-69 | |
| » Starters: Charlie Wagner vs Dutch Leonard | Second | 18½ out |
| » Defeated Senators (69-81), 5-4 | Griffith Stadium (5-6) | 82-69 | Won 2 |
| » Starters: Dick Newsome vs Dick Mulligan | Second | 18½ out |
| Saturday, September 27 |
| » Defeated Athletics (63-89), 5-1 | Shibe Park (7-2) | 83-69 | Won 3 |
| » Starters: Mickey Harris vs Roger Wolff | Second | 18½ out |
| Sunday, September 28 |
| » Defeated Athletics (63-90), 12-11 | Shibe Park (8-2) | 84-69 | Won 4 |
| » Starters: Dick Newsome vs Dick Fowler | Second | 18 out |
| » Lost to Athletics (64-90), 7-1 | Shibe Park (8-3) | 84-70 | |
| » Starters: Lefty Grove vs Fred Caligiuri | Second | 18 out |
| Sunday, October 5 |
| Future Red Sox Andy Kosco is born in Youngstown, OH. |
| Thursday, October 16 |
| Future Red Sox Tim McCarver is born in Memphis, TN. |
| Wednesday, October 22 |
| Future Red Sox Wilbur Wood is born in Cambridge, MA. |
| Tuesday, November 25 |
| Future Red Sox Mike Ryan is born in Haverhill, MA. |
| Saturday, December 27 |
| Future Red Sox Phil Gagliano is born in Memphis, TN. |
Game information provided by Retrosheet (www.retrosheet.org) |