| Sunday, February 25 |
| Future White Sox Danny Cater is born in Austin, TX. Future White Sox Ron Santo is born in Seattle, WA. |
| Tuesday, April 16 |
| » Lost to Indians (1-0), 1-0 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Bob Feller vs Eddie Smith | Second | 1 out |
| Saturday, April 20 |
| » Lost to Browns (2-1), 11-1 | Sportsman's Park III (0-1) | 0-2 | Lost 2 |
| » Starters: Johnny Rigney vs Elden Auker | Sixth | 2 out |
| Sunday, April 21 |
| » Defeated Browns (2-2), 6-2 | Sportsman's Park III (1-1) | 1-2 | |
| » Starters: Ted Lyons vs Slick Coffman | Fourth | 1½ out |
| Monday, April 22 |
| » Lost to Tigers (3-2), 6-5 | Comiskey Park I (0-2) | 1-3 | |
| » Starters: Lynn Nelson vs Vallie Eaves | Sixth | 2 out |
| » Major-league debuts: Dick Conger and Johnny Gorsica (Tigers) |
| Wednesday, April 24 |
| » Lost to Tigers (4-2), 2-1 | Comiskey Park I (0-3) | 1-4 | Lost 2 |
| » Starters: Tommy Bridges vs Johnny Rigney | Sixth | 3 out |
| Thursday, April 25 |
| » Lost to Indians (5-1), 3-1 | League Park II (0-1) | 1-5 | Lost 3 |
| » Starters: Eddie Smith vs Bob Feller | Eighth | 4 out |
| Friday, April 26 |
| » Defeated Indians (5-2), 11-1 | League Park II (1-1) | 2-5 | |
| » Starters: Thornton Lee vs Johnny Allen | Fifth | 3 out |
| Saturday, April 27 |
| » Lost to Browns (3-5), 6-2 | Comiskey Park I (0-4) | 2-6 | |
| » Starters: Jack Kramer vs Vallie Eaves | Seventh | 4 out |
| Sunday, April 28 |
| » Lost to Browns (4-5), 11-8 | Comiskey Park I (0-5) | 2-7 | Lost 2 |
| » Starters: Bob Harris vs Ted Lyons | Seventh | 5 out |
| Tuesday, April 30 |
| » Defeated Red Sox (7-4), 9-4 | Fenway Park (1-0) | 3-7 | |
| » Starters: Johnny Rigney vs Emerson Dickman | Seventh | 4½ out |
| Former White Sox Patsy Dougherty dies in Bolivar, NY at the age of 64. |
| Wednesday, May 1 |
| » Lost to Red Sox (8-4), 12-4 | Fenway Park (1-1) | 3-8 | |
| » Starters: Vallie Eaves vs Lefty Grove | Sixth | 4½ out |
| Friday, May 3 |
| » Lost to Yankees (6-6), 8-4 | Yankee Stadium (0-1) | 3-9 | Lost 2 |
| » Starters: Eddie Smith vs Marv Breuer | Eighth | 5½ out |
| Saturday, May 4 |
| » Defeated Yankees (6-7), 10-3 | Yankee Stadium (1-1) | 4-9 | |
| » Starters: Thornton Lee vs Steve Sundra | Seventh | 5½ out |
| Sunday, May 5 |
| » Defeated Athletics (6-9), 6-5 | Shibe Park (1-0) | 5-9 | Won 2 |
| » Starters: Ted Lyons vs Chubby Dean | Sixth | 5 out |
| Monday, May 6 |
| » Lost to Athletics (7-9), 3-2 | Shibe Park (1-1) | 5-10 | |
| » Starters: Johnny Rigney vs Nels Potter | Eighth | 5½ out |
| Tuesday, May 7 |
| » Defeated Athletics (7-10), 6-3 | Shibe Park (2-1) | 6-10 | |
| » Starters: Jack Knott vs George Caster | Sixth | 5½ out |
| Wednesday, May 8 |
| » Defeated Senators (7-11), 6-3 | Griffith Stadium (1-0) | 7-10 | Won 2 |
| » Starters: Eddie Smith vs Ken Chase | Fifth | 5½ out |
| Thursday, May 9 |
| » Lost to Senators (8-11), 8-4 | Griffith Stadium (1-1) | 7-11 | |
| » Starters: Thornton Lee vs Dutch Leonard | Sixth | 6½ out |
| Friday, May 10 |
| » Lost to Tigers (12-8), 3-0 | Tiger Stadium (0-1) | 7-12 | Lost 2 |
| » Starters: Johnny Rigney vs Bobo Newsom | Seventh | 7½ out |
| Saturday, May 11 |
| » Defeated Tigers (12-9), 1-0 | Tiger Stadium (1-1) | 8-12 | |
| » Starters: Jack Knott vs Tommy Bridges | Fifth | 7½ out |
| Sunday, May 12 |
| » Defeated Tigers (12-10), 4-3 | Tiger Stadium (2-1) | 9-12 | Won 2 |
| » Starters: Ted Lyons vs Lynn Nelson | Fifth | 6½ out |
| Tuesday, May 14 |
| » Lost to Red Sox (17-6), 7-6 | Comiskey Park I (0-6) | 9-13 | |
| » Starters: Lefty Grove vs Johnny Rigney | Seventh | 7½ out |
| Friday, May 17 |
| » Lost to Yankees (8-14), 6-1 | Comiskey Park I (0-7) | 9-14 | Lost 2 |
| » Starters: Marv Breuer vs Eddie Smith | Seventh | 8½ out |
| Saturday, May 18 |
| » Lost to Yankees (9-14), 3-0 | Comiskey Park I (0-8) | 9-15 | Lost 3 |
| » Starters: Monte Pearson vs Thornton Lee | Eighth | 9 out |
| Sunday, May 19 |
| » Lost to Senators (12-14), 12-10 | Comiskey Park I (0-9) | 9-16 | Lost 4 |
| » Starters: Dutch Leonard vs Ted Lyons | Eighth | 9½ out |
| Monday, May 20 |
| » Defeated Senators (12-15), 5-4 | Comiskey Park I (1-9) | 10-16 | |
| » Starters: Sid Hudson vs Johnny Rigney | Seventh | 8½ out |
| Tuesday, May 21 |
| » Defeated Senators (12-16), 9-8 | Comiskey Park I (2-9) | 11-16 | Won 2 |
| » Starters: Willis Hudlin vs Jack Knott | Seventh | 8½ out |
| Wednesday, May 22 |
| » Defeated Athletics (12-15), 10-1 | Comiskey Park I (3-9) | 12-16 | Won 3 |
| » Starters: George Caster vs Eddie Smith | Sixth | 7½ out |
| Thursday, May 23 |
| » Defeated Athletics (12-16), 13-4 | Comiskey Park I (4-9) | 13-16 | Won 4 |
| » Starters: Johnny Babich vs Thornton Lee | Fourth | 7 out |
| Friday, May 24 |
| » Defeated Tigers (15-14), 2-1 | Comiskey Park I (5-9) | 14-16 | Won 5 |
| » Starters: Tommy Bridges vs Johnny Rigney | Fourth | 6½ out |
| Saturday, May 25 |
| » Lost to Tigers (16-14), 10-4 | Comiskey Park I (5-10) | 14-17 | |
| » Starters: Dizzy Trout vs Jack Knott | Fourth | 7 out |
| Monday, May 27 |
| » Defeated Browns (12-18), 7-5 | Sportsman's Park III (2-1) | 15-17 | |
| » Starters: Ted Lyons vs Jack Kramer | Fourth | 6 out |
| Tuesday, May 28 |
| » Lost to Browns (13-18), 10-9 | Sportsman's Park III (2-2) | 15-18 | |
| » Starters: Johnny Rigney vs Vern Kennedy | Fifth | 7½ out |
| » Lost to Browns (14-18), 7-5 | Sportsman's Park III (2-3) | 15-19 | Lost 2 |
| » Starters: Jack Knott vs Bob Harris | Fifth | 7½ out |
| » Major-league debuts: Orval Grove (White Sox) |
| Wednesday, May 29 |
| » Defeated Browns (14-19), 4-3 | Sportsman's Park III (3-3) | 16-19 | |
| » Starters: Bill Dietrich vs Elden Auker | Fifth | 7½ out |
| Thursday, May 30 |
| » Lost to Indians (22-13), 3-1 | Cleveland Stadium (0-1) | 16-20 | |
| » Starters: Eddie Smith vs Al Smith | Fifth | 8½ out |
| » Lost to Indians (23-13), 3-1 | Cleveland Stadium (0-2) | 16-21 | Lost 2 |
| » Starters: Thornton Lee vs Al Milnar | Fifth | 8½ out |
| Saturday, June 1 |
| » Lost to Red Sox (23-10), 2-1 | Fenway Park (1-2) | 16-22 | Lost 3 |
| » Starters: Jack Knott vs Mickey Harris | Fifth | 9½ out |
| Sunday, June 2 |
| » Defeated Red Sox (23-11), 6-0 | Fenway Park (2-2) | 17-22 | |
| » Starters: Ted Lyons vs Bill Butland | Fifth | 9½ out |
| » Lost to Red Sox (24-11), 10-8 | Fenway Park (2-3) | 17-23 | |
| » Starters: Johnny Rigney vs Denny Galehouse | Fifth | 9½ out |
| Monday, June 3 |
| » Defeated Red Sox (24-12), 7-4 | Fenway Park (3-3) | 18-23 | |
| » Starters: Bill Dietrich vs Fritz Ostermueller | Fifth | 8½ out |
| Tuesday, June 4 |
| » Defeated Yankees (21-19), 7-3 | Yankee Stadium (2-1) | 19-23 | Won 2 |
| » Starters: Eddie Smith vs Red Ruffing | Fifth | 7½ out |
| Wednesday, June 5 |
| » Lost to Yankees (22-19), 7-5 | Yankee Stadium (2-2) | 19-24 | |
| » Starters: Thornton Lee vs Monte Pearson | Fifth | 7½ out |
| Thursday, June 6 |
| » Defeated Yankees (22-20), 4-3 | Yankee Stadium (3-2) | 20-24 | |
| » Starters: Johnny Rigney vs Spud Chandler | Fifth | 7½ out |
| Friday, June 7 |
| » Lost to Senators (20-26), 3-2 | Griffith Stadium (1-2) | 20-25 | |
| » Starters: Jack Knott vs Dutch Leonard | Fifth | 7½ out |
| Saturday, June 8 |
| » Defeated Senators (20-27), 12-6 | Griffith Stadium (2-2) | 21-25 | |
| » Starters: Bill Dietrich vs Ken Chase | Fifth | 6½ out |
| Sunday, June 9 |
| » Defeated Senators (20-28), 4-3 | Griffith Stadium (3-2) | 22-25 | Won 2 |
| » Starters: Ted Lyons vs Walt Masterson | Fifth | 6 out |
| Tuesday, June 11 |
| » Defeated Athletics (18-28), 5-4 | Shibe Park (3-1) | 23-25 | Won 3 |
| » Starters: Eddie Smith vs Buck Ross | Fifth | 6 out |
| Wednesday, June 12 |
| » Lost to Athletics (19-28), 3-2 | Shibe Park (3-2) | 23-26 | |
| » Starters: Thornton Lee vs Nels Potter | Fifth | 7 out |
| Friday, June 14 |
| » Lost to Red Sox (28-16), 5-1 | Comiskey Park I (5-11) | 23-27 | Lost 2 |
| » Starters: Denny Galehouse vs Johnny Rigney | Fifth | 8 out |
| Saturday, June 15 |
| » Lost to Red Sox (29-16), 5-2 | Comiskey Park I (5-12) | 23-28 | Lost 3 |
| » Starters: Herb Hash vs Bill Dietrich | Fifth | 9 out |
| Sunday, June 16 |
| » Lost to Red Sox (30-16), 4-3 | Comiskey Park I (5-13) | 23-29 | Lost 4 |
| » Starters: Lefty Grove vs Ted Lyons | Fifth | 11 out |
| » Lost to Red Sox (31-16), 14-5 | Comiskey Park I (5-14) | 23-30 | Lost 5 |
| » Starters: Jack Wilson vs Jack Knott | Fifth | 11 out |
| Tuesday, June 18 |
| » Defeated Yankees (27-25), 5-3 | Comiskey Park I (6-14) | 24-30 | |
| » Starters: Atley Donald vs Eddie Smith | Fifth | 10 out |
| Wednesday, June 19 |
| » Defeated Yankees (27-26), 1-0 | Comiskey Park I (7-14) | 25-30 | Won 2 |
| » Starters: Marius Russo vs Thornton Lee | Fifth | 9 out |
| Thursday, June 20 |
| » Defeated Yankees (27-27), 1-0 | Comiskey Park I (8-14) | 26-30 | Won 3 |
| » Starters: Monte Pearson vs Johnny Rigney | Sixth | 8½ out |
| Friday, June 21 |
| » Lost to Athletics (22-33), 12-1 | Comiskey Park I (8-15) | 26-31 | |
| » Starters: Buck Ross vs Jack Knott | Sixth | 9½ out |
| Tuesday, June 25 |
| » Lost to Senators (25-38), 7-6 | Comiskey Park I (8-16) | 26-32 | Lost 2 |
| » Starters: Sid Hudson vs Johnny Rigney | Sixth | 11½ out |
| Wednesday, June 26 |
| » Defeated Senators (25-39), 7-6 | Comiskey Park I (9-16) | 27-32 | |
| » Starters: Walt Masterson vs Eddie Smith | Sixth | 10½ out |
| Saturday, June 29 |
| » Lost to Indians (41-24), 7-3 | Comiskey Park I (9-17) | 27-33 | |
| » Starters: Bob Feller vs Thornton Lee | Sixth | 11½ out |
| Sunday, June 30 |
| » Lost to Indians (42-24), 7-5 | Comiskey Park I (9-18) | 27-34 | Lost 2 |
| » Starters: Al Smith vs Ted Lyons | Sixth | 11½ out |
| » Defeated Indians (42-25), 3-1 | Comiskey Park I (10-18) | 28-34 | |
| » Starters: Al Milnar vs Eddie Smith | Sixth | 11½ out |
| Monday, July 1 |
| » Lost to Tigers (39-25), 3-1 | Tiger Stadium (2-2) | 28-35 | |
| » Starters: Johnny Rigney vs Bobo Newsom | Sixth | 11½ out |
| Tuesday, July 2 |
| » Lost to Tigers (40-25), 10-9 | Tiger Stadium (2-3) | 28-36 | Lost 2 |
| » Starters: Bill Dietrich vs Tom Seats | Sixth | 11½ out |
| Wednesday, July 3 |
| » Defeated Tigers (40-26), 12-7 | Tiger Stadium (3-3) | 29-36 | |
| » Starters: Jack Knott vs Dizzy Trout | Sixth | 11½ out |
| Thursday, July 4 |
| » Defeated Browns (33-39), 7-3 | Comiskey Park I (11-18) | 30-36 | Won 2 |
| » Starters: Johnny Niggeling vs Thornton Lee | Fifth | 10½ out |
| » Defeated Browns (33-40), 8-5 | Comiskey Park I (12-18) | 31-36 | Won 3 |
| » Starters: Roxie Lawson vs Eddie Smith | Fifth | 10½ out |
| Friday, July 5 |
| » Defeated Browns (33-41), 10-8 | Comiskey Park I (13-18) | 32-36 | Won 4 |
| » Starters: Elden Auker vs Johnny Rigney | Fifth | 10 out |
| Saturday, July 6 |
| » Lost to Indians (45-28), 7-3 | League Park II (1-2) | 32-37 | |
| » Starters: Bill Dietrich vs Mel Harder | Fifth | 11 out |
| Sunday, July 7 |
| » Defeated Indians (45-29), 3-1 | Cleveland Stadium (1-2) | 33-37 | |
| » Starters: Ted Lyons vs Bob Feller | Fifth | 10½ out |
| Thursday, July 11 |
| » Lost to Red Sox (42-31), 3-2 | Fenway Park (3-4) | 33-38 | |
| » Starters: Johnny Rigney vs Herb Hash | Fifth | 11 out |
| Saturday, July 13 |
| » Defeated Red Sox (42-32), 5-0 | Fenway Park (4-4) | 34-38 | |
| » Starters: Ted Lyons vs Jim Bagby | Fifth | 11 out |
| » Defeated Red Sox (42-33), 7-0 | Fenway Park (5-4) | 35-38 | Won 2 |
| » Starters: Jack Knott vs Jack Wilson | Fifth | 11 out |
| Sunday, July 14 |
| » Lost to Yankees (41-35), 4-0 | Yankee Stadium (3-3) | 35-39 | |
| » Starters: Thornton Lee vs Red Ruffing | Fifth | 11 out |
| Monday, July 15 |
| » Defeated Yankees (41-36), 3-2 | Yankee Stadium (4-3) | 36-39 | |
| » Starters: Eddie Smith vs Marv Breuer | Fifth | 10 out |
| Tuesday, July 16 |
| » Defeated Yankees (41-37), 5-1 | Yankee Stadium (5-3) | 37-39 | Won 2 |
| » Starters: Johnny Rigney vs Marius Russo | Fifth | 9 out |
| Wednesday, July 17 |
| » Lost to Senators (35-48), 5-2 | Griffith Stadium (3-3) | 37-40 | |
| » Starters: Bill Dietrich vs Dutch Leonard | Fourth | 9 out |
| Thursday, July 18 |
| » Lost to Senators (36-48), 5-4 | Griffith Stadium (3-4) | 37-41 | Lost 2 |
| » Starters: Jack Knott vs Ken Chase | Fifth | 9½ out |
| Friday, July 19 |
| » Defeated Senators (36-49), 9-1 | Griffith Stadium (4-4) | 38-41 | |
| » Starters: Thornton Lee vs Walt Masterson | Fifth | 9½ out |
| Saturday, July 20 |
| » Defeated Athletics (33-49), 19-7 | Shibe Park (4-2) | 39-41 | Won 2 |
| » Starters: Eddie Smith vs George Caster | Fifth | 9½ out |
| Sunday, July 21 |
| » Defeated Athletics (33-50), 10-8 | Shibe Park (5-2) | 40-41 | Won 3 |
| » Starters: Ted Lyons vs Porter Vaughan | Fifth | 9½ out |
| » Defeated Athletics (33-51), 7-2 | Shibe Park (6-2) | 41-41 | Won 4 |
| » Starters: Johnny Rigney vs Nels Potter | Fifth | 9½ out |
| Tuesday, July 23 |
| » Defeated Red Sox (47-39), 8-7 | Comiskey Park I (14-18) | 42-41 | Won 5 |
| » Starters: Herb Hash vs Thornton Lee | Fifth | 8½ out |
| Future White Sox Hank Allen is born in Wampum, PA. |
| Wednesday, July 24 |
| » Defeated Red Sox (47-40), 12-10 | Comiskey Park I (15-18) | 43-41 | Won 6 |
| » Starters: Denny Galehouse vs Bill Dietrich | Fifth | 8½ out |
| Thursday, July 25 |
| » Defeated Red Sox (47-41), 6-4 | Comiskey Park I (16-18) | 44-41 | Won 7 |
| » Starters: Jim Bagby vs Jack Knott | Fourth | 8½ out |
| Friday, July 26 |
| » Lost to Yankees (46-42), 10-2 | Comiskey Park I (16-19) | 44-42 | |
| » Starters: Spud Chandler vs Eddie Smith | Fifth | 8½ out |
| Saturday, July 27 |
| » Defeated Yankees (46-43), 6-5 | Comiskey Park I (17-19) | 45-42 | |
| » Starters: Marv Breuer vs Johnny Rigney | Fifth | 9 out |
| Sunday, July 28 |
| » Lost to Yankees (47-43), 10-9 | Comiskey Park I (17-20) | 45-43 | |
| » Starters: Marius Russo vs Ted Lyons | Fourth | 8½ out |
| » Defeated Yankees (47-44), 8-4 | Comiskey Park I (18-20) | 46-43 | |
| » Starters: Bump Hadley vs Thornton Lee | Fourth | 8½ out |
| Tuesday, July 30 |
| » Defeated Athletics (37-56), 3-1 | Comiskey Park I (19-20) | 47-43 | Won 2 |
| » Starters: Buck Ross vs Jack Knott | Fourth | 7 out |
| Wednesday, July 31 |
| » Lost to Athletics (38-56), 4-3 | Comiskey Park I (19-21) | 47-44 | |
| » Starters: Bill Beckmann vs Johnny Rigney | Fourth | 8 out |
| Thursday, August 1 |
| » Defeated Athletics (38-57), 5-4 | Comiskey Park I (20-21) | 48-44 | |
| » Starters: Nels Potter vs Eddie Smith | Fourth | 8 out |
| Friday, August 2 |
| » Defeated Senators (42-56), 10-2 | Comiskey Park I (21-21) | 49-44 | Won 2 |
| » Starters: Sid Hudson vs Thornton Lee | Fourth | 7 out |
| Saturday, August 3 |
| » Defeated Senators (42-57), 7-6 | Comiskey Park I (22-21) | 50-44 | Won 3 |
| » Starters: Rene Monteagudo vs Jack Knott | Third | 7½ out |
| Sunday, August 4 |
| » Lost to Senators (43-57), 4-3 | Comiskey Park I (22-22) | 50-45 | |
| » Starters: Dutch Leonard vs Ted Lyons | Fourth | 8 out |
| » Lost to Senators (44-57), 1-0 | Comiskey Park I (22-23) | 50-46 | Lost 2 |
| » Starters: Ken Chase vs Johnny Rigney | Fourth | 8 out |
| Monday, August 5 |
| » Lost to Indians (60-40), 10-1 | Comiskey Park I (22-24) | 50-47 | Lost 3 |
| » Starters: Mel Harder vs Eddie Smith | Fourth | 8½ out |
| Tuesday, August 6 |
| » Defeated Indians (60-41), 5-1 | Comiskey Park I (23-24) | 51-47 | |
| » Starters: Al Milnar vs Thornton Lee | Fourth | 9 out |
| » Lost to Indians (61-41), 3-2 | Comiskey Park I (23-25) | 51-48 | |
| » Starters: Johnny Allen vs Bill Dietrich | Fourth | 9 out |
| Wednesday, August 7 |
| » Lost to Indians (62-41), 9-3 | Comiskey Park I (23-26) | 51-49 | Lost 2 |
| » Starters: Al Smith vs Johnny Rigney | Fourth | 10 out |
| Friday, August 9 |
| » Defeated Tigers (63-42), 3-2 | Comiskey Park I (24-26) | 52-49 | |
| » Starters: Dizzy Trout vs Eddie Smith | Fourth | 9 out |
| Saturday, August 10 |
| » Lost to Tigers (64-42), 5-2 | Comiskey Park I (24-27) | 52-50 | |
| » Starters: Schoolboy Rowe vs Thornton Lee | Fourth | 10 out |
| Sunday, August 11 |
| » Defeated Tigers (64-43), 4-3 | Comiskey Park I (25-27) | 53-50 | |
| » Starters: Bobo Newsom vs Ted Lyons | Third | 8 out |
| » Defeated Tigers (64-44), 4-3 | Comiskey Park I (26-27) | 54-50 | Won 2 |
| » Starters: Tommy Bridges vs Johnny Rigney | Third | 8 out |
| Monday, August 12 |
| » Defeated Browns (46-65), 6-5 | Sportsman's Park III (4-3) | 55-50 | Won 3 |
| » Starters: Jack Knott vs Elden Auker | Fourth | 8 out |
| Tuesday, August 13 |
| » Defeated Browns (46-66), 4-3 | Sportsman's Park III (5-3) | 56-50 | Won 4 |
| » Starters: Bill Dietrich vs Vern Kennedy | Fourth | 8 out |
| Wednesday, August 14 |
| » Lost to Indians (67-44), 4-0 | Cleveland Stadium (1-3) | 56-51 | |
| » Starters: Eddie Smith vs Al Smith | Fourth | 9 out |
| Thursday, August 15 |
| » Lost to Indians (68-44), 5-4 | League Park II (1-3) | 56-52 | Lost 2 |
| » Starters: Thornton Lee vs Al Milnar | Fourth | 10 out |
| Friday, August 16 |
| » Defeated Tigers (66-47), 13-4 | Tiger Stadium (4-3) | 57-52 | |
| » Starters: Johnny Rigney vs Tommy Bridges | Fourth | 10 out |
| Saturday, August 17 |
| » Defeated Tigers (66-48), 9-5 | Tiger Stadium (5-3) | 58-52 | Won 2 |
| » Starters: Jack Knott vs Dizzy Trout | Fourth | 9 out |
| Sunday, August 18 |
| » Defeated Tigers (66-49), 7-5 | Tiger Stadium (6-3) | 59-52 | Won 3 |
| » Starters: Ted Lyons vs Johnny Gorsica | Fourth | 8½ out |
| Tuesday, August 20 |
| » Defeated Athletics (43-68), 6-1 | Shibe Park (7-2) | 60-52 | Won 4 |
| » Starters: Eddie Smith vs Buck Ross | Fourth | 8½ out |
| » Lost to Athletics (44-68), 4-3 | Shibe Park (7-3) | 60-53 | |
| » Starters: Thornton Lee vs Nels Potter | Fourth | 8½ out |
| Wednesday, August 21 |
| » Lost to Athletics (45-68), 3-0 | Shibe Park (7-4) | 60-54 | Lost 2 |
| » Starters: Johnny Rigney vs Bill Beckmann | Fourth | 9½ out |
| Friday, August 23 |
| » Lost to Senators (51-65), 3-2 | Griffith Stadium (4-5) | 60-55 | Lost 3 |
| » Starters: Bill Dietrich vs Ken Chase | Fifth | 9 out |
| Saturday, August 24 |
| » Defeated Senators (51-66), 4-2 | Griffith Stadium (5-5) | 61-55 | |
| » Starters: Jack Knott vs Walt Masterson | Fifth | 7½ out |
| » Defeated Senators (51-67), 2-1 | Griffith Stadium (6-5) | 62-55 | Won 2 |
| » Starters: Eddie Smith vs Joe Krakauskas | Fifth | 7½ out |
| » Major-league debuts: Jack Sanford (Senators) |
| Sunday, August 25 |
| » Defeated Yankees (63-55), 1-0 | Yankee Stadium (6-3) | 63-55 | Won 3 |
| » Starters: Ted Lyons vs Red Ruffing | Fifth | 7 out |
| » Lost to Yankees (64-55), 3-1 | Yankee Stadium (6-4) | 63-56 | |
| » Starters: Thornton Lee vs Tiny Bonham | Fifth | 7 out |
| Tuesday, August 27 |
| » Lost to Yankees (65-55), 5-4 | Yankee Stadium (6-5) | 63-57 | Lost 2 |
| » Starters: Johnny Rigney vs Spud Chandler | Fifth | 8 out |
| Wednesday, August 28 |
| » Defeated Red Sox (66-58), 3-2 | Fenway Park (6-4) | 64-57 | |
| » Starters: Bill Dietrich vs Bill Fleming | Fifth | 7½ out |
| Thursday, August 29 |
| » Lost to Red Sox (67-58), 4-3 | Fenway Park (6-5) | 64-58 | |
| » Starters: Jack Knott vs Jack Wilson | Fifth | 8 out |
| Friday, August 30 |
| » Lost to Indians (73-50), 4-2 | Comiskey Park I (26-28) | 64-59 | Lost 2 |
| » Starters: Bob Feller vs Thornton Lee | Fifth | 9 out |
| Saturday, August 31 |
| » Lost to Indians (74-50), 5-4 | Comiskey Park I (26-29) | 64-60 | Lost 3 |
| » Starters: Al Smith vs Eddie Smith | Fifth | 10 out |
| Sunday, September 1 |
| » Lost to Indians (75-50), 7-4 | Comiskey Park I (26-30) | 64-61 | Lost 4 |
| » Starters: Al Milnar vs Ted Lyons | Fifth | 11 out |
| Former White Sox Gus Dundon dies in Pittsburgh, PA at the age of 67. |
| Monday, September 2 |
| » Defeated Tigers (72-55), 2-1 | Comiskey Park I (27-30) | 65-61 | |
| » Starters: Bobo Newsom vs Bill Dietrich | Fifth | 9 out |
| » Defeated Tigers (72-56), 4-0 | Comiskey Park I (28-30) | 66-61 | Won 2 |
| » Starters: Dizzy Trout vs Johnny Rigney | Fifth | 9 out |
| Tuesday, September 3 |
| » Defeated Tigers (72-57), 10-2 | Comiskey Park I (29-30) | 67-61 | Won 3 |
| » Starters: Fred Hutchinson vs Jack Knott | Fifth | 8½ out |
| Wednesday, September 4 |
| » Lost to Browns (55-76), 4-1 | Comiskey Park I (29-31) | 67-62 | |
| » Starters: Bob Harris vs Thornton Lee | Fifth | 8½ out |
| Thursday, September 5 |
| » Defeated Browns (55-77), 4-2 | Comiskey Park I (30-31) | 68-62 | |
| » Starters: Bill Trotter vs Eddie Smith | Fifth | 7½ out |
| Friday, September 6 |
| » Defeated Browns (55-78), 6-3 | Comiskey Park I (31-31) | 69-62 | Won 2 |
| » Starters: Elden Auker vs Johnny Rigney | Fifth | 6½ out |
| Saturday, September 7 |
| » Defeated Indians (75-56), 5-4 | Cleveland Stadium (2-3) | 70-62 | Won 3 |
| » Starters: Bill Dietrich vs Mel Harder | Fifth | 5½ out |
| Sunday, September 8 |
| » Lost to Indians (76-56), 5-4 | Cleveland Stadium (2-4) | 70-63 | |
| » Starters: Ted Lyons vs Al Milnar | Fifth | 6½ out |
| Monday, September 9 |
| » Defeated Indians (76-57), 2-1 | Cleveland Stadium (3-4) | 71-63 | |
| » Starters: Thornton Lee vs Harry Eisenstat | Fifth | 6 out |
| Tuesday, September 10 |
| » Lost to Senators (58-77), 5-2 | Comiskey Park I (31-32) | 71-64 | |
| » Starters: Ken Chase vs Jack Knott | Fifth | 6 out |
| Wednesday, September 11 |
| » Defeated Senators (58-78), 7-4 | Comiskey Park I (32-32) | 72-64 | |
| » Starters: Dutch Leonard vs Johnny Rigney | Fifth | 6 out |
| Thursday, September 12 |
| » Defeated Athletics (50-80), 1-0 | Comiskey Park I (33-32) | 73-64 | Won 2 |
| » Starters: Buck Ross vs Bill Dietrich | Fourth | 5½ out |
| » Defeated Athletics (50-81), 4-3 | Comiskey Park I (34-32) | 74-64 | Won 3 |
| » Starters: Johnny Babich vs Eddie Smith | Fourth | 5½ out |
| Friday, September 13 |
| » Defeated Athletics (50-82), 6-2 | Comiskey Park I (35-32) | 75-64 | Won 4 |
| » Starters: Ed Heusser vs Thornton Lee | Fourth | 5 out |
| » Defeated Athletics (50-83), 8-4 | Comiskey Park I (36-32) | 76-64 | Won 5 |
| » Starters: Bill Beckmann vs Jack Hallett | Fourth | 5 out |
| Saturday, September 14 |
| » Defeated Athletics (50-84), 6-3 | Comiskey Park I (37-32) | 77-64 | Won 6 |
| » Starters: Nels Potter vs Jack Knott | Fourth | 4 out |
| Sunday, September 15 |
| » Defeated Red Sox (74-66), 5-1 | Comiskey Park I (38-32) | 78-64 | Won 7 |
| » Starters: Joe Heving vs Ted Lyons | Third | 3½ out |
| » Defeated Red Sox (74-67), 4-2 | Comiskey Park I (39-32) | 79-64 | Won 8 |
| » Starters: Bill Fleming vs Johnny Rigney | Third | 3½ out |
| Monday, September 16 |
| » Lost to Red Sox (75-67), 6-2 | Comiskey Park I (39-33) | 79-65 | |
| » Starters: Jack Wilson vs Bill Dietrich | Third | 4 out |
| Tuesday, September 17 |
| Future White Sox Cisco Carlos is born in Monrovia, CA. |
| Wednesday, September 18 |
| » Defeated Yankees (78-65), 6-3 | Comiskey Park I (40-33) | 80-65 | |
| » Starters: Spud Chandler vs Thornton Lee | Fourth | 4½ out |
| » Lost to Yankees (79-65), 9-8 | Comiskey Park I (40-34) | 80-66 | |
| » Starters: Marv Breuer vs Eddie Smith | Fourth | 4½ out |
| Thursday, September 19 |
| » Lost to Yankees (80-65), 10-1 | Comiskey Park I (40-35) | 80-67 | Lost 2 |
| » Starters: Red Ruffing vs Jack Knott | Third | 5½ out |
| Friday, September 20 |
| » Lost to Browns (64-83), 7-6 | Sportsman's Park III (5-4) | 80-68 | Lost 3 |
| » Starters: Jack Hallett vs Maury Newlin | Fourth | 6½ out |
| Saturday, September 21 |
| » Lost to Browns (65-83), 3-2 | Sportsman's Park III (5-5) | 80-69 | Lost 4 |
| » Starters: Eddie Smith vs Vern Kennedy | Fourth | 7½ out |
| Sunday, September 22 |
| » Defeated Browns (65-84), 10-0 | Sportsman's Park III (6-5) | 81-69 | |
| » Starters: Ted Lyons vs Bob Harris | Fourth | 6½ out |
| Wednesday, September 25 |
| » Lost to Tigers (88-62), 10-9 | Tiger Stadium (6-4) | 81-70 | |
| » Starters: Thornton Lee vs Tommy Bridges | Fourth | 8½ out |
| » Lost to Tigers (89-62), 3-2 | Tiger Stadium (6-5) | 81-71 | Lost 2 |
| » Starters: Johnny Rigney vs Bobo Newsom | Fourth | 8½ out |
| Friday, September 27 |
| » Defeated Browns (66-86), 4-3 | Comiskey Park I (41-35) | 82-71 | |
| » Starters: Bob Harris vs Bill Dietrich | Fourth | 8½ out |
| Saturday, September 28 |
| » Defeated Browns (66-87), 5-1 | Comiskey Park I (42-35) | 83-71 | Won 2 |
| » Starters: Jack Kramer vs Eddie Smith | Fourth | 7½ out |
| Sunday, September 29 |
| » Lost to Browns (67-87), 2-1 | Comiskey Park I (42-36) | 83-72 | |
| » Starters: Elden Auker vs Johnny Rigney | Fourth | 7½ out |
| Wednesday, October 16 |
| Future White Sox Dave DeBusschere is born in Detroit, MI. |
| Thursday, October 17 |
| Former White Sox George Davis dies in Philadelphia, PA at the age of 71. |
| Thursday, November 21 |
| Future White Sox Tom McCraw is born in Malvern, AR. |
Game information provided by Retrosheet (www.retrosheet.org) |
