| Tuesday, April 16 |
| » Defeated Yankees (0-1), 2-1 | Shibe Park (1-0) | 1-0 | |
| » Starters: Red Ruffing vs Chubby Dean | First | -- |
| Wednesday, April 17 |
| » Lost to Yankees (1-1), 4-1 | Shibe Park (1-1) | 1-1 | |
| » Starters: Monte Pearson vs Nels Potter | Second | ½ out |
| Friday, April 19 |
| » Lost to Red Sox (3-0), 7-6 | Fenway Park (0-1) | 1-2 | Lost 2 |
| » Starters: George Caster vs Jack Wilson | Fifth | 1 out |
| » Defeated Red Sox (3-1), 3-1 | Fenway Park (1-1) | 2-2 | |
| » Starters: Johnny Babich vs Emerson Dickman | Fifth | 1 out |
| Tuesday, April 23 |
| » Defeated Yankees (2-2), 3-0 | Yankee Stadium (1-0) | 3-2 | Won 2 |
| » Starters: Chubby Dean vs Bump Hadley | Third | 1 out |
| Wednesday, April 24 |
| » Lost to Yankees (3-2), 9-4 | Yankee Stadium (1-1) | 3-3 | |
| » Starters: Herman Besse vs Red Ruffing | Fourth | 1½ out |
| Thursday, April 25 |
| » Lost to Senators (2-4), 7-6 | Griffith Stadium (0-1) | 3-4 | Lost 2 |
| » Starters: George Caster vs Joe Krakauskas | Fifth | 2½ out |
| » Major-league debuts: Gil Torres (Senators) |
| Friday, April 26 |
| » Lost to Senators (3-4), 8-6 | Griffith Stadium (0-2) | 3-5 | Lost 3 |
| » Starters: Nels Potter vs Al Hollingsworth | Fourth | 2½ out |
| Saturday, April 27 |
| » Defeated Red Sox (5-3), 8-3 | Shibe Park (2-1) | 4-5 | |
| » Starters: Jim Bagby vs Johnny Babich | Fourth | 2½ out |
| Sunday, April 28 |
| » Lost to Red Sox (6-3), 5-4 | Shibe Park (2-2) | 4-6 | |
| » Starters: Denny Galehouse vs Chubby Dean | Fifth | 3½ out |
| Monday, April 29 |
| » Lost to Red Sox (7-3), 11-3 | Shibe Park (2-3) | 4-7 | Lost 2 |
| » Starters: Mickey Harris vs George Caster | Fifth | 3½ out |
| Tuesday, April 30 |
| » Lost to Indians (8-3), 10-5 | Shibe Park (2-4) | 4-8 | Lost 3 |
| » Starters: Willis Hudlin vs Herman Besse | Sixth | 4½ out |
| Wednesday, May 1 |
| » Defeated Indians (8-4), 5-1 | Shibe Park (3-4) | 5-8 | |
| » Starters: Johnny Allen vs Nels Potter | Fifth | 3½ out |
| Saturday, May 4 |
| » Defeated Tigers (8-6), 14-5 | Shibe Park (4-4) | 6-8 | Won 2 |
| » Starters: Fred Hutchinson vs Johnny Babich | Fifth | 4 out |
| » Major-league debuts: Tom Seats (Tigers) |
| Sunday, May 5 |
| » Lost to White Sox (5-9), 6-5 | Shibe Park (4-5) | 6-9 | |
| » Starters: Ted Lyons vs Chubby Dean | Fifth | 4½ out |
| Monday, May 6 |
| » Defeated White Sox (5-10), 3-2 | Shibe Park (5-5) | 7-9 | |
| » Starters: Johnny Rigney vs Nels Potter | Fifth | 4 out |
| Tuesday, May 7 |
| » Lost to White Sox (6-10), 6-3 | Shibe Park (5-6) | 7-10 | |
| » Starters: Jack Knott vs George Caster | Fifth | 5 out |
| Wednesday, May 8 |
| » Defeated Browns (7-10), 10-8 | Shibe Park (6-6) | 8-10 | |
| » Starters: Jack Kramer vs Buck Ross | Fourth | 5 out |
| Thursday, May 9 |
| » Lost to Browns (8-10), 4-2 | Shibe Park (6-7) | 8-11 | |
| » Starters: Bob Harris vs Johnny Babich | Fifth | 6 out |
| Friday, May 10 |
| » Defeated Senators (8-12), 8-7 | Shibe Park (7-7) | 9-11 | |
| » Starters: Joe Krakauskas vs Chubby Dean | Fourth | 6 out |
| Saturday, May 11 |
| » Lost to Senators (9-12), 9-6 | Shibe Park (7-8) | 9-12 | |
| » Starters: Sid Hudson vs Nels Potter | Fourth | 7 out |
| Sunday, May 12 |
| » Defeated Senators (9-13), 4-2 | Shibe Park (8-8) | 10-12 | |
| » Starters: Ken Chase vs Johnny Babich | Fourth | 6 out |
| Tuesday, May 14 |
| » Defeated Indians (14-8), 9-7 | League Park II (1-0) | 11-12 | Won 2 |
| » Starters: Herman Besse vs Bob Feller | Fourth | 6 out |
| Saturday, May 18 |
| » Lost to Tigers (13-11), 8-6 | Tiger Stadium (0-1) | 11-13 | |
| » Starters: Johnny Babich vs Bobo Newsom | Fourth | 7 out |
| Sunday, May 19 |
| » Lost to Browns (10-13), 10-4 | Sportsman's Park III (0-1) | 11-14 | Lost 2 |
| » Starters: Herman Besse vs Elden Auker | Fifth | 7½ out |
| Monday, May 20 |
| » Defeated Browns (10-14), 8-4 | Sportsman's Park III (1-1) | 12-14 | |
| » Starters: Chubby Dean vs Emil Bildilli | Fourth | 6½ out |
| Wednesday, May 22 |
| » Lost to White Sox (12-16), 10-1 | Comiskey Park I (0-1) | 12-15 | |
| » Starters: George Caster vs Eddie Smith | Fifth | 7 out |
| Thursday, May 23 |
| » Lost to White Sox (13-16), 13-4 | Comiskey Park I (0-2) | 12-16 | Lost 2 |
| » Starters: Johnny Babich vs Thornton Lee | Sixth | 7½ out |
| Saturday, May 25 |
| » Lost to Senators (14-17), 4-2 | Griffith Stadium (0-3) | 12-17 | Lost 3 |
| » Starters: Chubby Dean vs Dutch Leonard | Fifth | 8 out |
| Sunday, May 26 |
| » Lost to Senators (15-17), 4-3 | Griffith Stadium (0-4) | 12-18 | Lost 4 |
| » Starters: George Caster vs Willis Hudlin | Seventh | 8 out |
| Tuesday, May 28 |
| » Lost to Red Sox (20-9), 4-1 | Shibe Park (8-9) | 12-19 | Lost 5 |
| » Starters: Denny Galehouse vs Johnny Babich | Eighth | 9 out |
| Wednesday, May 29 |
| » Lost to Red Sox (21-9), 8-3 | Shibe Park (8-10) | 12-20 | Lost 6 |
| » Starters: Bill Butland vs Nels Potter | Eighth | 10 out |
| Thursday, May 30 |
| » Defeated Senators (15-22), 7-6 | Shibe Park (9-10) | 13-20 | |
| » Starters: Ken Chase vs Chubby Dean | Eighth | 10 out |
| » Lost to Senators (16-22), 14-2 | Shibe Park (9-11) | 13-21 | |
| » Starters: Walt Masterson vs George Caster | Eighth | 10 out |
| Saturday, June 1 |
| » Defeated Indians (23-14), 6-1 | Shibe Park (10-11) | 14-21 | |
| » Starters: Johnny Allen vs Buck Ross | Seventh | 10 out |
| Sunday, June 2 |
| » Lost to Indians (24-14), 7-2 | Shibe Park (10-12) | 14-22 | |
| » Starters: Bob Feller vs Nels Potter | Sixth | 10 out |
| » Defeated Indians (24-15), 12-6 | Shibe Park (11-12) | 15-22 | |
| » Starters: Mike Naymick vs Johnny Babich | Sixth | 10 out |
| Monday, June 3 |
| » Lost to Indians (25-15), 4-0 | Shibe Park (11-13) | 15-23 | |
| » Starters: Al Milnar vs Chubby Dean | Seventh | 10 out |
| Tuesday, June 4 |
| » Defeated Tigers (22-17), 8-6 | Shibe Park (12-13) | 16-23 | |
| » Starters: Tommy Bridges vs Johnny Babich | Seventh | 9 out |
| Wednesday, June 5 |
| » Lost to Tigers (23-17), 9-1 | Shibe Park (12-14) | 16-24 | |
| » Starters: Schoolboy Rowe vs George Caster | Seventh | 9 out |
| Thursday, June 6 |
| » Defeated Tigers (23-18), 7-4 | Shibe Park (13-14) | 17-24 | |
| » Starters: Bobo Newsom vs Buck Ross | Seventh | 9 out |
| Friday, June 7 |
| » Defeated Browns (16-27), 3-2 | Shibe Park (14-14) | 18-24 | Won 2 |
| » Starters: Vern Kennedy vs Nels Potter | Seventh | 8 out |
| Saturday, June 8 |
| » Lost to Browns (17-27), 15-1 | Shibe Park (14-15) | 18-25 | |
| » Starters: Elden Auker vs Chubby Dean | Seventh | 8 out |
| Sunday, June 9 |
| » Lost to Browns (18-27), 8-7 | Shibe Park (14-16) | 18-26 | Lost 2 |
| » Starters: Bob Harris vs Johnny Babich | Eighth | 9 out |
| » Lost to Browns (19-27), 4-2 | Shibe Park (14-17) | 18-27 | Lost 3 |
| » Starters: Johnny Niggeling vs George Caster | Eighth | 9 out |
| Tuesday, June 11 |
| » Lost to White Sox (23-25), 5-4 | Shibe Park (14-18) | 18-28 | Lost 4 |
| » Starters: Eddie Smith vs Buck Ross | Eighth | 10 out |
| Wednesday, June 12 |
| » Defeated White Sox (23-26), 3-2 | Shibe Park (15-18) | 19-28 | |
| » Starters: Thornton Lee vs Nels Potter | Eighth | 10 out |
| Friday, June 14 |
| » Lost to Indians (30-21), 8-0 | League Park II (1-1) | 19-29 | |
| » Starters: Chubby Dean vs Johnny Allen | Eighth | 11 out |
| Saturday, June 15 |
| » Defeated Indians (30-22), 7-4 | League Park II (2-1) | 20-29 | |
| » Starters: Buck Ross vs Mel Harder | Seventh | 11 out |
| » Major-league debuts: Crash Davis (Athletics) |
| Sunday, June 16 |
| » Lost to Indians (31-22), 4-2 | Cleveland Stadium (0-1) | 20-30 | |
| » Starters: Porter Vaughan vs Bob Feller | Sixth | 13 out |
| » Lost to Indians (32-22), 4-3 | Cleveland Stadium (0-2) | 20-31 | Lost 2 |
| » Starters: Johnny Babich vs Al Milnar | Sixth | 13 out |
| Wednesday, June 19 |
| » Lost to Tigers (31-20), 5-4 | Tiger Stadium (0-2) | 20-32 | Lost 3 |
| » Starters: Nels Potter vs Bobo Newsom | Sixth | 13 out |
| » Lost to Tigers (32-20), 9-4 | Tiger Stadium (0-3) | 20-33 | Lost 4 |
| » Starters: George Caster vs Schoolboy Rowe | Sixth | 13 out |
| Thursday, June 20 |
| » Defeated Tigers (32-21), 6-4 | Tiger Stadium (1-3) | 21-33 | |
| » Starters: Chubby Dean vs Hal Newhouser | Seventh | 12½ out |
| Friday, June 21 |
| » Defeated White Sox (26-31), 12-1 | Comiskey Park I (1-2) | 22-33 | Won 2 |
| » Starters: Buck Ross vs Jack Knott | Seventh | 12½ out |
| Monday, June 24 |
| » Lost to Browns (29-33), 9-4 | Sportsman's Park III (1-2) | 22-34 | |
| » Starters: Johnny Babich vs Elden Auker | Seventh | 14 out |
| Former Athletic Axel Lindstrom dies in Asheville, NC at the age of 45. |
| Tuesday, June 25 |
| » Lost to Browns (30-33), 12-10 | Sportsman's Park III (1-3) | 22-35 | Lost 2 |
| » Starters: Nels Potter vs Vern Kennedy | Eighth | 15 out |
| Wednesday, June 26 |
| » Defeated Browns (30-34), 9-4 | Sportsman's Park III (2-3) | 23-35 | |
| » Starters: George Caster vs Johnny Niggeling | Seventh | 14 out |
| Friday, June 28 |
| » Lost to Yankees (30-31), 4-1 | Yankee Stadium (1-2) | 23-36 | |
| » Starters: Buck Ross vs Marius Russo | Eighth | 14½ out |
| Saturday, June 29 |
| » Lost to Yankees (31-31), 12-9 | Yankee Stadium (1-3) | 23-37 | Lost 2 |
| » Starters: Chubby Dean vs Spud Chandler | Eighth | 15½ out |
| Sunday, June 30 |
| » Lost to Yankees (32-31), 4-3 | Yankee Stadium (1-4) | 23-38 | Lost 3 |
| » Starters: Porter Vaughan vs Marv Breuer | Eighth | 15½ out |
| » Defeated Yankees (32-32), 3-2 | Yankee Stadium (2-4) | 24-38 | |
| » Starters: Johnny Babich vs Monte Pearson | Eighth | 15½ out |
| Monday, July 1 |
| » Defeated Red Sox (36-27), 9-1 | Fenway Park (2-1) | 25-38 | Won 2 |
| » Starters: Nels Potter vs Jim Bagby | Seventh | 14½ out |
| Tuesday, July 2 |
| » Defeated Red Sox (36-28), 4-3 | Fenway Park (3-1) | 26-38 | Won 3 |
| » Starters: Ed Heusser vs Denny Galehouse | Seventh | 14 out |
| » Lost to Red Sox (37-28), 15-9 | Fenway Park (3-2) | 26-39 | |
| » Starters: George Caster vs Mickey Harris | Seventh | 14 out |
| Wednesday, July 3 |
| » Lost to Red Sox (38-28), 12-11 | Fenway Park (3-3) | 26-40 | Lost 2 |
| » Starters: Herman Besse vs Charlie Wagner | Seventh | 15 out |
| Thursday, July 4 |
| » Lost to Senators (28-43), 5-1 | Griffith Stadium (0-5) | 26-41 | Lost 3 |
| » Starters: George Caster vs Sid Hudson | Eighth | 16 out |
| » Lost to Senators (29-43), 9-5 | Griffith Stadium (0-6) | 26-42 | Lost 4 |
| » Starters: Bill Beckmann vs Joe Krakauskas | Eighth | 16 out |
| Friday, July 5 |
| » Defeated Yankees (36-33), 6-3 | Shibe Park (16-18) | 27-42 | |
| » Starters: Monte Pearson vs Johnny Babich | Eighth | 15½ out |
| Saturday, July 6 |
| » Defeated Yankees (36-34), 8-7 | Shibe Park (17-18) | 28-42 | Won 2 |
| » Starters: Red Ruffing vs Buck Ross | Seventh | 15½ out |
| Sunday, July 7 |
| » Lost to Yankees (37-34), 6-3 | Shibe Park (17-19) | 28-43 | |
| » Starters: Marv Breuer vs Porter Vaughan | Seventh | 15½ out |
| » Defeated Yankees (37-35), 10-5 | Shibe Park (18-19) | 29-43 | |
| » Starters: Lefty Gomez vs Nels Potter | Seventh | 15½ out |
| Thursday, July 11 |
| » Lost to Indians (46-29), 8-5 | Shibe Park (18-20) | 29-44 | |
| » Starters: Al Milnar vs Chubby Dean | Eighth | 16 out |
| Friday, July 12 |
| » Lost to Indians (47-29), 1-0 | Shibe Park (18-21) | 29-45 | Lost 2 |
| » Starters: Bob Feller vs Johnny Babich | Eighth | 17 out |
| Saturday, July 13 |
| » Lost to Indians (48-29), 6-4 | Shibe Park (18-22) | 29-46 | Lost 3 |
| » Starters: Mel Harder vs Buck Ross | Eighth | 18 out |
| Sunday, July 14 |
| » Defeated Tigers (46-29), 8-2 | Shibe Park (19-22) | 30-46 | |
| » Starters: Schoolboy Rowe vs Porter Vaughan | Sixth | 16½ out |
| » Defeated Tigers (46-30), 5-2 | Shibe Park (20-22) | 31-46 | Won 2 |
| » Starters: Johnny Gorsica vs Nels Potter | Sixth | 16½ out |
| Monday, July 15 |
| » Lost to Tigers (47-30), 9-8 | Shibe Park (20-23) | 31-47 | |
| » Starters: Hal Newhouser vs Ed Heusser | Eighth | 16½ out |
| Tuesday, July 16 |
| » Defeated Tigers (47-31), 3-1 | Shibe Park (21-23) | 32-47 | |
| » Starters: Fred Hutchinson vs George Caster | Seventh | 15½ out |
| Thursday, July 18 |
| » Defeated Browns (33-51), 10-3 | Shibe Park (22-23) | 33-47 | Won 2 |
| » Starters: Bob Harris vs Johnny Babich | Seventh | 14½ out |
| Friday, July 19 |
| » Lost to Browns (34-51), 9-7 | Shibe Park (22-24) | 33-48 | |
| » Starters: Vern Kennedy vs Buck Ross | Seventh | 15½ out |
| Saturday, July 20 |
| » Lost to White Sox (39-41), 19-7 | Shibe Park (22-25) | 33-49 | Lost 2 |
| » Starters: Eddie Smith vs George Caster | Eighth | 16½ out |
| Sunday, July 21 |
| » Lost to White Sox (40-41), 10-8 | Shibe Park (22-26) | 33-50 | Lost 3 |
| » Starters: Ted Lyons vs Porter Vaughan | Eighth | 18½ out |
| » Lost to White Sox (41-41), 7-2 | Shibe Park (22-27) | 33-51 | Lost 4 |
| » Starters: Johnny Rigney vs Nels Potter | Eighth | 18½ out |
| Tuesday, July 23 |
| » Lost to Indians (52-35), 1-0 | Cleveland Stadium (0-3) | 33-52 | Lost 5 |
| » Starters: Johnny Babich vs Al Milnar | Eighth | 18½ out |
| Wednesday, July 24 |
| » Lost to Indians (53-35), 7-6 | League Park II (2-2) | 33-53 | Lost 6 |
| » Starters: Chubby Dean vs Al Smith | Seventh | 19½ out |
| Thursday, July 25 |
| » Defeated Indians (53-36), 7-6 | League Park II (3-2) | 34-53 | |
| » Starters: Buck Ross vs Mel Harder | Seventh | 19½ out |
| Friday, July 26 |
| » Defeated Tigers (54-35), 7-4 | Tiger Stadium (2-3) | 35-53 | Won 2 |
| » Starters: George Caster vs Tommy Bridges | Seventh | 18½ out |
| Saturday, July 27 |
| » Lost to Tigers (55-35), 15-2 | Tiger Stadium (2-4) | 35-54 | |
| » Starters: Nels Potter vs Schoolboy Rowe | Seventh | 20½ out |
| » Lost to Tigers (56-35), 8-7 | Tiger Stadium (2-5) | 35-55 | Lost 2 |
| » Starters: Porter Vaughan vs Johnny Gorsica | Seventh | 20½ out |
| Sunday, July 28 |
| » Defeated Tigers (56-36), 9-5 | Tiger Stadium (3-5) | 36-55 | |
| » Starters: Johnny Babich vs Bobo Newsom | Eighth | 19½ out |
| Monday, July 29 |
| » Defeated Tigers (56-37), 9-7 | Tiger Stadium (4-5) | 37-55 | Won 2 |
| » Starters: Chubby Dean vs Fred Hutchinson | Eighth | 18½ out |
| Tuesday, July 30 |
| » Lost to White Sox (47-43), 3-1 | Comiskey Park I (1-3) | 37-56 | |
| » Starters: Buck Ross vs Jack Knott | Seventh | 18½ out |
| Wednesday, July 31 |
| » Defeated White Sox (47-44), 4-3 | Comiskey Park I (2-3) | 38-56 | |
| » Starters: Bill Beckmann vs Johnny Rigney | Sixth | 18½ out |
| Thursday, August 1 |
| » Lost to White Sox (48-44), 5-4 | Comiskey Park I (2-4) | 38-57 | |
| » Starters: Nels Potter vs Eddie Smith | Eighth | 19½ out |
| Friday, August 2 |
| » Lost to Browns (40-58), 5-0 | Sportsman's Park III (2-4) | 38-58 | Lost 2 |
| » Starters: Johnny Babich vs Bob Harris | Eighth | 19½ out |
| Saturday, August 3 |
| » Defeated Browns (40-59), 11-7 | Sportsman's Park III (3-4) | 39-58 | |
| » Starters: Porter Vaughan vs Johnny Niggeling | Eighth | 20 out |
| Sunday, August 4 |
| » Lost to Browns (41-59), 5-4 | Sportsman's Park III (3-5) | 39-59 | |
| » Starters: Chubby Dean vs Vern Kennedy | Eighth | 20½ out |
| » Lost to Browns (42-59), 6-4 | Sportsman's Park III (3-6) | 39-60 | Lost 2 |
| » Starters: George Caster vs Elden Auker | Eighth | 20½ out |
| Tuesday, August 6 |
| » Lost to Senators (45-57), 11-0 | Griffith Stadium (0-7) | 39-61 | Lost 3 |
| » Starters: Buck Ross vs Sid Hudson | Eighth | 21½ out |
| Thursday, August 8 |
| » Defeated Senators (45-58), 6-4 | Griffith Stadium (1-7) | 40-61 | |
| » Starters: George Caster vs Walt Masterson | Eighth | 21½ out |
| Friday, August 9 |
| » Lost to Yankees (51-52), 2-0 | Yankee Stadium (2-5) | 40-62 | |
| » Starters: Johnny Babich vs Red Ruffing | Eighth | 21½ out |
| Saturday, August 10 |
| » Lost to Yankees (52-52), 13-0 | Yankee Stadium (2-6) | 40-63 | Lost 2 |
| » Starters: Nels Potter vs Tiny Bonham | Eighth | 22½ out |
| Sunday, August 11 |
| » Lost to Yankees (53-52), 7-6 | Yankee Stadium (2-7) | 40-64 | Lost 3 |
| » Starters: Porter Vaughan vs Spud Chandler | Seventh | 22 out |
| Tuesday, August 13 |
| » Defeated Senators (47-60), 6-3 | Shibe Park (23-27) | 41-64 | |
| » Starters: Dutch Leonard vs Johnny Babich | Eighth | 22½ out |
| Wednesday, August 14 |
| » Lost to Senators (48-60), 5-3 | Shibe Park (23-28) | 41-65 | |
| » Starters: Ken Chase vs Nels Potter | Eighth | 23½ out |
| Thursday, August 15 |
| » Lost to Senators (49-60), 9-4 | Shibe Park (23-29) | 41-66 | Lost 2 |
| » Starters: Sid Hudson vs George Caster | Eighth | 24 out |
| » Defeated Senators (49-61), 6-5 | Shibe Park (24-29) | 42-66 | |
| » Starters: Walt Masterson vs Bill Beckmann | Eighth | 24 out |
| Sunday, August 18 |
| » Lost to Yankees (57-53), 9-1 | Shibe Park (24-30) | 42-67 | |
| » Starters: Steve Sundra vs Porter Vaughan | Eighth | 24 out |
| » Defeated Yankees (57-54), 7-3 | Shibe Park (25-30) | 43-67 | |
| » Starters: Marv Breuer vs Johnny Babich | Eighth | 24 out |
| Tuesday, August 20 |
| » Lost to White Sox (60-52), 6-1 | Shibe Park (25-31) | 43-68 | |
| » Starters: Eddie Smith vs Buck Ross | Eighth | 24 out |
| » Defeated White Sox (60-53), 4-3 | Shibe Park (26-31) | 44-68 | |
| » Starters: Thornton Lee vs Nels Potter | Eighth | 24 out |
| Wednesday, August 21 |
| » Defeated White Sox (60-54), 3-0 | Shibe Park (27-31) | 45-68 | Won 2 |
| » Starters: Johnny Rigney vs Bill Beckmann | Seventh | 24 out |
| Thursday, August 22 |
| » Lost to Browns (49-70), 8-4 | Shibe Park (27-32) | 45-69 | |
| » Starters: Bob Harris vs Johnny Babich | Eighth | 24 out |
| Friday, August 23 |
| » Defeated Browns (49-71), 6-4 | Shibe Park (28-32) | 46-69 | |
| » Starters: Vern Kennedy vs Porter Vaughan | Eighth | 23 out |
| Saturday, August 24 |
| » Lost to Browns (50-71), 6-5 | Shibe Park (28-33) | 46-70 | |
| » Starters: Elden Auker vs Nels Potter | Eighth | 23 out |
| Sunday, August 25 |
| » Lost to Tigers (69-53), 7-3 | Shibe Park (28-34) | 46-71 | Lost 2 |
| » Starters: Bobo Newsom vs Buck Ross | Eighth | 23 out |
| Friday, August 30 |
| » Lost to Red Sox (68-58), 5-4 | Shibe Park (28-35) | 46-72 | Lost 3 |
| » Starters: Fritz Ostermueller vs Bill Beckmann | Eighth | 24½ out |
| Saturday, August 31 |
| » Lost to Red Sox (69-58), 10-6 | Shibe Park (28-36) | 46-73 | Lost 4 |
| » Starters: Jim Bagby vs George Caster | Eighth | 25½ out |
| Monday, September 2 |
| » Lost to Yankees (71-55), 6-3 | Yankee Stadium (2-8) | 46-74 | Lost 5 |
| » Starters: Porter Vaughan vs Marius Russo | Eighth | 25 out |
| » Defeated Yankees (71-56), 3-0 | Yankee Stadium (3-8) | 47-74 | |
| » Starters: Johnny Babich vs Spud Chandler | Eighth | 25 out |
| Wednesday, September 4 |
| » Lost to Red Sox (70-60), 6-5 | Fenway Park (3-4) | 47-75 | |
| » Starters: Buck Ross vs Jack Wilson | Eighth | 25½ out |
| » Lost to Red Sox (71-60), 5-4 | Fenway Park (3-5) | 47-76 | Lost 2 |
| » Starters: Nels Potter vs Fritz Ostermueller | Eighth | 25½ out |
| Thursday, September 5 |
| » Lost to Red Sox (72-60), 9-7 | Fenway Park (3-6) | 47-77 | Lost 3 |
| » Starters: George Caster vs Jim Bagby | Eighth | 25½ out |
| Saturday, September 7 |
| » Defeated Senators (56-76), 8-5 | Griffith Stadium (2-7) | 48-77 | |
| » Starters: Johnny Babich vs Joe Haynes | Eighth | 24 out |
| Sunday, September 8 |
| » Lost to Senators (57-76), 7-6 | Griffith Stadium (2-8) | 48-78 | |
| » Starters: Porter Vaughan vs Sid Hudson | Eighth | 24½ out |
| » Defeated Senators (57-77), 4-0 | Griffith Stadium (3-8) | 49-78 | |
| » Starters: Bill Beckmann vs Red Anderson | Eighth | 24½ out |
| » Major-league debuts: Jim Mallory and Sherry Robertson (Senators) |
| Tuesday, September 10 |
| » Defeated Browns (55-81), 6-4 | Sportsman's Park III (4-6) | 50-78 | Won 2 |
| » Starters: Nels Potter vs Bob Harris | Eighth | 23½ out |
| Wednesday, September 11 |
| » Lost to Browns (56-81), 3-0 | Sportsman's Park III (4-7) | 50-79 | |
| » Starters: George Caster vs Elden Auker | Eighth | 24½ out |
| Thursday, September 12 |
| » Lost to White Sox (73-64), 1-0 | Comiskey Park I (2-5) | 50-80 | Lost 2 |
| » Starters: Buck Ross vs Bill Dietrich | Eighth | 26 out |
| » Lost to White Sox (74-64), 4-3 | Comiskey Park I (2-6) | 50-81 | Lost 3 |
| » Starters: Johnny Babich vs Eddie Smith | Eighth | 26 out |
| Friday, September 13 |
| » Lost to White Sox (75-64), 6-2 | Comiskey Park I (2-7) | 50-82 | Lost 4 |
| » Starters: Ed Heusser vs Thornton Lee | Eighth | 27½ out |
| » Lost to White Sox (76-64), 8-4 | Comiskey Park I (2-8) | 50-83 | Lost 5 |
| » Starters: Bill Beckmann vs Jack Hallett | Eighth | 27½ out |
| Saturday, September 14 |
| » Lost to White Sox (77-64), 6-3 | Comiskey Park I (2-9) | 50-84 | Lost 6 |
| » Starters: Nels Potter vs Jack Knott | Eighth | 27½ out |
| Sunday, September 15 |
| » Lost to Indians (80-59), 5-0 | Cleveland Stadium (0-4) | 50-85 | Lost 7 |
| » Starters: Porter Vaughan vs Bob Feller | Eighth | 29 out |
| » Lost to Indians (81-59), 8-5 | Cleveland Stadium (0-5) | 50-86 | Lost 8 |
| » Starters: George Caster vs Al Smith | Eighth | 29 out |
| Monday, September 16 |
| » Lost to Indians (82-59), 8-3 | Cleveland Stadium (0-6) | 50-87 | Lost 9 |
| » Starters: Buck Ross vs Mel Harder | Eighth | 29 out |
| » Defeated Indians (82-60), 3-2 | Cleveland Stadium (1-6) | 51-87 | |
| » Starters: Johnny Babich vs Harry Eisenstat | Eighth | 29 out |
| Tuesday, September 17 |
| » Defeated Indians (82-61), 4-3 | Cleveland Stadium (2-6) | 52-87 | Won 2 |
| » Starters: Bill Beckmann vs Al Milnar | Eighth | 28½ out |
| Wednesday, September 18 |
| » Lost to Tigers (83-60), 14-0 | Tiger Stadium (4-6) | 52-88 | |
| » Starters: George Caster vs Tommy Bridges | Eighth | 29 out |
| » Defeated Tigers (83-61), 13-6 | Tiger Stadium (5-6) | 53-88 | |
| » Starters: Ed Heusser vs Johnny Gorsica | Eighth | 29 out |
| » Major-league debuts: Pat Mullin (Tigers) |
| Thursday, September 19 |
| » Lost to Tigers (84-61), 13-2 | Tiger Stadium (5-7) | 53-89 | |
| » Starters: Chubby Dean vs Floyd Giebell | Seventh | 30½ out |
| » Lost to Tigers (85-61), 10-1 | Tiger Stadium (5-8) | 53-90 | Lost 2 |
| » Starters: Nels Potter vs Dizzy Trout | Seventh | 30½ out |
| Sunday, September 22 |
| » Lost to Senators (61-85), 5-4 | Shibe Park (28-37) | 53-91 | Lost 3 |
| » Starters: Sid Hudson vs Johnny Babich | Eighth | 32 out |
| » Lost to Senators (62-85), 5-2 | Shibe Park (28-38) | 53-92 | Lost 4 |
| » Starters: Ken Chase vs Phil Marchildon | Eighth | 32 out |
| Tuesday, September 24 |
| » Lost to Red Sox (76-71), 16-8 | Shibe Park (28-39) | 53-93 | Lost 5 |
| » Starters: Joe Heving vs Ed Heusser | Eighth | 33 out |
| » Lost to Red Sox (77-71), 4-3 | Shibe Park (28-40) | 53-94 | Lost 6 |
| » Starters: Jack Wilson vs Bill Beckmann | Eighth | 33 out |
| Thursday, September 26 |
| » Lost to Yankees (85-65), 5-4 | Shibe Park (28-41) | 53-95 | Lost 7 |
| » Starters: Red Ruffing vs Porter Vaughan | Eighth | 35 out |
| » Lost to Yankees (86-65), 2-0 | Shibe Park (28-42) | 53-96 | Lost 8 |
| » Starters: Tiny Bonham vs Buck Ross | Eighth | 35 out |
| Friday, September 27 |
| » Defeated Yankees (86-66), 6-2 | Shibe Park (29-42) | 54-96 | |
| » Starters: Marius Russo vs Johnny Babich | Eighth | 35 out |
| Saturday, September 28 |
| » Lost to Red Sox (79-72), 16-4 | Fenway Park (3-7) | 54-97 | |
| » Starters: Chubby Dean vs Joe Heving | Eighth | 35½ out |
| » Lost to Red Sox (80-72), 8-1 | Fenway Park (3-8) | 54-98 | Lost 2 |
| » Starters: Ed Heusser vs Jack Wilson | Eighth | 35½ out |
| Sunday, September 29 |
| » Lost to Red Sox (81-72), 9-4 | Fenway Park (3-9) | 54-99 | Lost 3 |
| » Starters: Porter Vaughan vs Bill Fleming | Eighth | 36 out |
| » Lost to Red Sox (82-72), 4-1 | Fenway Park (3-10) | 54-100 | Lost 4 |
| » Starters: Phil Marchildon vs Woody Rich | Eighth | 36 out |
Game information provided by Retrosheet (www.retrosheet.org) |