| Tuesday, February 7 |
| Future White Sox Frank Kreutzer is born in Buffalo, NY. |
| Saturday, February 18 |
| Future White Sox Bob Miller is born in St. Louis, MO. |
| Saturday, March 4 |
| Future White Sox Jack Fisher is born in Frostburg, MD. |
| Sunday, March 12 |
| Future White Sox Johnny Callison is born in Qualls, OK. |
| Tuesday, March 21 |
| Future White Sox Tommy Davis is born in Brooklyn, NY. |
| Tuesday, April 18 |
| » Lost to Tigers (1-0), 6-1 | Tiger Stadium (0-1) | 0-1 | |
| » Starters: Johnny Rigney vs Tommy Bridges | Third | 1 out |
| » Major-league debuts: Frank Croucher and Barney McCosky (Tigers) Ken Silvestri (White Sox) |
| Thursday, April 20 |
| » Lost to Tigers (2-0), 8-7 | Tiger Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: John Whitehead vs Al Benton | Fifth | 2 out |
| Friday, April 21 |
| » Major-league debuts: Floyd Giebell (Tigers) |
| Saturday, April 22 |
| » Lost to Browns (1-0), 5-1 | Comiskey Park I (0-1) | 0-3 | Lost 3 |
| » Starters: Bobo Newsom vs Ted Lyons | Sixth | 2½ out |
| » Major-league debuts: Johnny Berardino (Browns) |
| Sunday, April 23 |
| » Defeated Browns (1-1), 17-4 | Comiskey Park I (1-1) | 1-3 | |
| » Starters: Johnny Marcum vs Johnny Rigney | Sixth | 2 out |
| » Major-league debuts: Ewald Pyle (Browns) |
| Monday, April 24 |
| » Defeated Indians (2-2), 9-3 | League Park II (1-0) | 2-3 | Won 2 |
| » Starters: Thornton Lee vs Johnny Humphries | Fourth | 2 out |
| Tuesday, April 25 |
| » Lost to Indians (3-2), 7-1 | League Park II (1-1) | 2-4 | |
| » Starters: John Whitehead vs Bob Feller | Sixth | 3 out |
| Wednesday, April 26 |
| » Defeated Indians (3-3), 5-1 | League Park II (2-1) | 3-4 | |
| » Starters: Bill Dietrich vs Johnny Broaca | Fourth | 2½ out |
| » Major-league debuts: Joe Dobson (Indians) |
| Thursday, April 27 |
| » Defeated Tigers (5-4), 2-1 | Comiskey Park I (2-1) | 4-4 | Won 2 |
| » Starters: Al Benton vs Jack Knott | Fourth | 2 out |
| Saturday, April 29 |
| » Defeated Browns (4-4), 9-8 | Sportsman's Park III (1-0) | 5-4 | Won 3 |
| » Starters: Johnny Rigney vs Jack Kramer | Third | 1 out |
| Sunday, April 30 |
| » Defeated Browns (4-5), 6-5 | Sportsman's Park III (2-0) | 6-4 | Won 4 |
| » Starters: Thornton Lee vs Bobo Newsom | Second | 1 out |
| Tuesday, May 2 |
| » Defeated Athletics (2-8), 4-1 | Comiskey Park I (3-1) | 7-4 | Won 5 |
| » Starters: Roy Parmelee vs Ted Lyons | Second | 1 out |
| Wednesday, May 3 |
| » Lost to Athletics (3-8), 3-1 | Comiskey Park I (3-2) | 7-5 | |
| » Starters: George Caster vs Bill Dietrich | Fourth | 1 out |
| Thursday, May 4 |
| » Defeated Senators (7-5), 4-3 | Comiskey Park I (4-2) | 8-5 | |
| » Starters: Ken Chase vs Johnny Rigney | Third | 1 out |
| » Major-league debuts: Jake Early (Senators) |
| Friday, May 5 |
| » Defeated Senators (7-6), 2-1 | Comiskey Park I (5-2) | 9-5 | Won 2 |
| » Starters: Joe Krakauskas vs Thornton Lee | Third | 1½ out |
| Saturday, May 6 |
| » Defeated Senators (7-7), 14-12 | Comiskey Park I (6-2) | 10-5 | Won 3 |
| » Starters: Jimmie DeShong vs Jack Knott | Third | 1½ out |
| Sunday, May 7 |
| » Lost to Yankees (10-4), 15-4 | Comiskey Park I (6-3) | 10-6 | |
| » Starters: Red Ruffing vs John Whitehead | Third | 1 out |
| Monday, May 8 |
| » Defeated Yankees (10-5), 5-3 | Comiskey Park I (7-3) | 11-6 | |
| » Starters: Wes Ferrell vs Eddie Smith | Third | 2 out |
| Tuesday, May 9 |
| » Lost to Yankees (11-5), 8-6 | Comiskey Park I (7-4) | 11-7 | |
| » Starters: Steve Sundra vs Thornton Lee | Third | 2 out |
| Thursday, May 11 |
| » Defeated Red Sox (10-5), 3-2 | Comiskey Park I (8-4) | 12-7 | |
| » Starters: Woody Rich vs Ted Lyons | Third | 1½ out |
| Friday, May 12 |
| » Defeated Indians (9-10), 4-3 | Comiskey Park I (9-4) | 13-7 | Won 2 |
| » Starters: Johnny Allen vs Johnny Rigney | Third | 1 out |
| Saturday, May 13 |
| » Lost to Indians (10-10), 5-2 | Comiskey Park I (9-5) | 13-8 | |
| » Starters: Willis Hudlin vs Eddie Smith | Third | 1½ out |
| Sunday, May 14 |
| » Lost to Indians (11-10), 9-4 | Comiskey Park I (9-6) | 13-9 | Lost 2 |
| » Starters: Bob Feller vs Thornton Lee | Third | 2½ out |
| Tuesday, May 16 |
| » Lost to Red Sox (13-5), 18-4 | Fenway Park (0-1) | 13-10 | Lost 3 |
| » Starters: Johnny Rigney vs Woody Rich | Third | 4 out |
| Wednesday, May 17 |
| » Defeated Red Sox (13-6), 6-3 | Fenway Park (1-1) | 14-10 | |
| » Starters: Bill Dietrich vs Jack Wilson | Third | 4 out |
| Thursday, May 18 |
| » Lost to Red Sox (14-6), 5-3 | Fenway Park (1-2) | 14-11 | |
| » Starters: John Whitehead vs Elden Auker | Third | 5 out |
| Friday, May 19 |
| » Lost to Yankees (19-5), 4-2 | Yankee Stadium (0-1) | 14-12 | Lost 2 |
| » Starters: Eddie Smith vs Red Ruffing | Fourth | 6 out |
| Saturday, May 20 |
| » Lost to Yankees (20-5), 5-2 | Yankee Stadium (0-2) | 14-13 | Lost 3 |
| » Starters: Thornton Lee vs Oral Hildebrand | Fourth | 7 out |
| Sunday, May 21 |
| » Defeated Senators (11-15), 3-2 | Griffith Stadium (1-0) | 15-13 | |
| » Starters: Ted Lyons vs Joe Krakauskas | Third | 7 out |
| Tuesday, May 23 |
| » Defeated Senators (11-16), 5-4 | Griffith Stadium (2-0) | 16-13 | Won 2 |
| » Starters: Jack Knott vs Joe Haynes | Third | 7 out |
| Wednesday, May 24 |
| » Defeated Athletics (11-17), 4-1 | Shibe Park (1-0) | 17-13 | Won 3 |
| » Starters: Eddie Smith vs Buck Ross | Third | 6 out |
| Friday, May 26 |
| » Defeated Indians (15-15), 2-1 | League Park II (3-1) | 18-13 | Won 4 |
| » Starters: Bill Dietrich vs Mel Harder | Third | 6½ out |
| Saturday, May 27 |
| » Lost to Indians (16-15), 7-6 | League Park II (3-2) | 18-14 | |
| » Starters: Johnny Rigney vs Al Milnar | Third | 8 out |
| Sunday, May 28 |
| » Lost to Indians (17-15), 6-0 | Cleveland Stadium (0-1) | 18-15 | Lost 2 |
| » Starters: Thornton Lee vs Johnny Allen | Third | 9 out |
| Tuesday, May 30 |
| » Defeated Tigers (15-22), 6-2 | Comiskey Park I (10-6) | 19-15 | |
| » Starters: Schoolboy Rowe vs Ted Lyons | Fourth | 9½ out |
| » Lost to Tigers (16-22), 8-3 | Comiskey Park I (10-7) | 19-16 | |
| » Starters: Dizzy Trout vs Jack Knott | Fourth | 9½ out |
| Thursday, June 1 |
| » Lost to Senators (15-22), 10-7 | Comiskey Park I (10-8) | 19-17 | Lost 2 |
| » Starters: Dutch Leonard vs Eddie Smith | Fourth | 10½ out |
| Friday, June 2 |
| » Defeated Senators (15-23), 7-5 | Comiskey Park I (11-8) | 20-17 | |
| » Starters: Joe Haynes vs Thornton Lee | Third | 10½ out |
| Saturday, June 3 |
| » Defeated Senators (15-24), 8-7 | Comiskey Park I (12-8) | 21-17 | Won 2 |
| » Starters: Alex Carrasquel vs Johnny Rigney | Third | 10½ out |
| Sunday, June 4 |
| » Defeated Athletics (16-23), 14-9 | Comiskey Park I (13-8) | 22-17 | Won 3 |
| » Starters: Cotton Pippen vs Ted Lyons | Third | 11 out |
| » Lost to Athletics (17-23), 11-6 | Comiskey Park I (13-9) | 22-18 | |
| » Starters: Nels Potter vs Bill Dietrich | Third | 11 out |
| Monday, June 5 |
| » Defeated Athletics (17-24), 12-1 | Comiskey Park I (14-9) | 23-18 | |
| » Starters: Bob Joyce vs Jack Knott | Third | 10 out |
| Tuesday, June 6 |
| » Defeated Athletics (17-25), 7-4 | Comiskey Park I (15-9) | 24-18 | Won 2 |
| » Starters: George Caster vs Bill Dietrich | Third | 9 out |
| Wednesday, June 7 |
| » Lost to Yankees (34-9), 5-2 | Comiskey Park I (15-10) | 24-19 | |
| » Starters: Lefty Gomez vs Thornton Lee | Third | 10 out |
| Thursday, June 8 |
| » Lost to Yankees (35-9), 7-2 | Comiskey Park I (15-11) | 24-20 | Lost 2 |
| » Starters: Atley Donald vs Eddie Smith | Third | 11 out |
| Sunday, June 11 |
| » Defeated Red Sox (26-17), 7-5 | Comiskey Park I (16-11) | 25-20 | |
| » Starters: Lefty Grove vs Ted Lyons | Fourth | 12 out |
| » Lost to Red Sox (27-17), 4-3 | Comiskey Park I (16-12) | 25-21 | |
| » Starters: Elden Auker vs Bill Dietrich | Fourth | 12 out |
| Wednesday, June 14 |
| » Lost to Senators (19-31), 3-0 | Griffith Stadium (2-1) | 25-22 | Lost 2 |
| » Starters: Johnny Rigney vs Dutch Leonard | Fourth | 12 out |
| Thursday, June 15 |
| » Defeated Senators (19-32), 5-1 | Griffith Stadium (3-1) | 26-22 | |
| » Starters: Jack Knott vs Joe Haynes | Fourth | 11½ out |
| » Defeated Senators (19-33), 4-2 | Griffith Stadium (4-1) | 27-22 | Won 2 |
| » Starters: Thornton Lee vs Ken Chase | Fourth | 11½ out |
| Friday, June 16 |
| » Lost to Senators (20-33), 5-2 | Griffith Stadium (4-2) | 27-23 | |
| » Starters: Vic Frasier vs Harry Kelley | Fourth | 12½ out |
| Saturday, June 17 |
| » Lost to Athletics (20-31), 5-2 | Shibe Park (1-1) | 27-24 | Lost 2 |
| » Starters: Bill Dietrich vs George Caster | Fourth | 13½ out |
| Sunday, June 18 |
| » Defeated Athletics (20-32), 6-5 | Shibe Park (2-1) | 28-24 | |
| » Starters: Ted Lyons vs Cotton Pippen | Third | 13 out |
| » Lost to Athletics (21-32), 9-4 | Shibe Park (2-2) | 28-25 | |
| » Starters: Johnny Rigney vs Nels Potter | Third | 13 out |
| Tuesday, June 20 |
| » Lost to Yankees (42-11), 13-3 | Yankee Stadium (0-3) | 28-26 | Lost 2 |
| » Starters: Jack Knott vs Monte Pearson | Fifth | 14½ out |
| Wednesday, June 21 |
| » Lost to Yankees (43-11), 9-8 | Yankee Stadium (0-4) | 28-27 | Lost 3 |
| » Starters: Thornton Lee vs Lefty Gomez | Fifth | 15½ out |
| Thursday, June 22 |
| » Lost to Yankees (44-11), 6-1 | Yankee Stadium (0-5) | 28-28 | Lost 4 |
| » Starters: Eddie Smith vs Atley Donald | Fifth | 16½ out |
| Saturday, June 24 |
| » Defeated Red Sox (31-23), 14-6 | Fenway Park (2-2) | 29-28 | |
| » Starters: Johnny Marcum vs Jim Bagby | Fifth | 16½ out |
| Tuesday, June 27 |
| » Defeated Browns (17-43), 11-2 | Comiskey Park I (17-12) | 30-28 | Won 2 |
| » Starters: Bill Trotter vs Ted Lyons | Fifth | 15½ out |
| Thursday, June 29 |
| » Lost to Browns (18-43), 9-3 | Comiskey Park I (17-13) | 30-29 | |
| » Starters: Bob Harris vs Thornton Lee | Fifth | 16½ out |
| » Defeated Browns (18-44), 7-5 | Comiskey Park I (18-13) | 31-29 | |
| » Starters: Vern Kennedy vs Johnny Marcum | Fifth | 16½ out |
| Friday, June 30 |
| » Lost to Tigers (34-30), 3-1 | Tiger Stadium (0-3) | 31-30 | |
| » Starters: Johnny Rigney vs Bobo Newsom | Fifth | 17½ out |
| Saturday, July 1 |
| » Lost to Tigers (35-30), 6-5 | Tiger Stadium (0-4) | 31-31 | Lost 2 |
| » Starters: Jack Knott vs Al Benton | Fifth | 17 out |
| » Defeated Tigers (35-31), 4-3 | Tiger Stadium (1-4) | 32-31 | |
| » Starters: Eddie Smith vs Dizzy Trout | Fifth | 17 out |
| Sunday, July 2 |
| » Lost to Tigers (36-31), 5-1 | Tiger Stadium (1-5) | 32-32 | |
| » Starters: Ted Lyons vs Tommy Bridges | Fifth | 17½ out |
| Monday, July 3 |
| » Defeated Browns (19-47), 8-3 | Sportsman's Park III (3-0) | 33-32 | |
| » Starters: Johnny Marcum vs Bob Harris | Fifth | 17 out |
| Tuesday, July 4 |
| » Defeated Browns (19-48), 7-3 | Sportsman's Park III (4-0) | 34-32 | Won 2 |
| » Starters: Johnny Rigney vs Jack Kramer | Fifth | 16 out |
| » Defeated Browns (19-49), 7-4 | Sportsman's Park III (5-0) | 35-32 | Won 3 |
| » Starters: Thornton Lee vs Harry Kimberlin | Fifth | 16 out |
| Wednesday, July 5 |
| » Defeated Indians (36-32), 2-1 | Comiskey Park I (19-13) | 36-32 | Won 4 |
| » Starters: Harry Eisenstat vs Eddie Smith | Fourth | 16 out |
| Thursday, July 6 |
| » Defeated Indians (36-33), 8-1 | Comiskey Park I (20-13) | 37-32 | Won 5 |
| » Starters: Johnny Allen vs Jack Knott | Fourth | 15½ out |
| Friday, July 7 |
| » Lost to Indians (37-33), 7-3 | Comiskey Park I (20-14) | 37-33 | |
| » Starters: Bob Feller vs Johnny Marcum | Fourth | 15½ out |
| Saturday, July 8 |
| » Defeated Tigers (38-34), 10-5 | Comiskey Park I (21-14) | 38-33 | |
| » Starters: Tommy Bridges vs Thornton Lee | Third | 14 out |
| Sunday, July 9 |
| » Defeated Tigers (38-35), 4-3 | Comiskey Park I (22-14) | 39-33 | Won 2 |
| » Starters: Bobo Newsom vs Ted Lyons | Third | 12 out |
| » Defeated Tigers (38-36), 6-3 | Comiskey Park I (23-14) | 40-33 | Won 3 |
| » Starters: Schoolboy Rowe vs Johnny Rigney | Third | 12 out |
| Thursday, July 13 |
| » Lost to Athletics (29-46), 12-10 | Comiskey Park I (23-15) | 40-34 | |
| » Starters: Nels Potter vs Eddie Smith | Third | 12 out |
| Friday, July 14 |
| » Lost to Athletics (30-46), 7-3 | Comiskey Park I (23-16) | 40-35 | Lost 2 |
| » Starters: Buck Ross vs Jack Knott | Third | 13 out |
| Saturday, July 15 |
| » Defeated Athletics (30-47), 7-3 | Comiskey Park I (24-16) | 41-35 | |
| » Starters: Nels Potter vs Johnny Rigney | Third | 13 out |
| Sunday, July 16 |
| » Defeated Senators (33-49), 3-2 | Comiskey Park I (25-16) | 42-35 | Won 2 |
| » Starters: Dutch Leonard vs Ted Lyons | Third | 13 out |
| » Defeated Senators (33-50), 6-3 | Comiskey Park I (26-16) | 43-35 | Won 3 |
| » Starters: Pete Appleton vs Thornton Lee | Third | 13 out |
| Monday, July 17 |
| » Major-league debuts: Bill Sayles (Red Sox) |
| Tuesday, July 18 |
| » Lost to Red Sox (48-26), 13-10 | Comiskey Park I (26-17) | 43-36 | |
| » Starters: Elden Auker vs Bill Dietrich | Third | 14½ out |
| » Defeated Red Sox (48-27), 8-5 | Comiskey Park I (27-17) | 44-36 | |
| » Starters: Jack Wilson vs Johnny Marcum | Third | 14½ out |
| Wednesday, July 19 |
| » Defeated Red Sox (48-28), 4-1 | Comiskey Park I (28-17) | 45-36 | Won 2 |
| » Starters: Jake Wade vs Jack Knott | Third | 13½ out |
| » Defeated Red Sox (48-29), 8-0 | Comiskey Park I (29-17) | 46-36 | Won 3 |
| » Starters: Fritz Ostermueller vs Johnny Rigney | Third | 13½ out |
| Thursday, July 20 |
| » Defeated Red Sox (48-30), 4-0 | Comiskey Park I (30-17) | 47-36 | Won 4 |
| » Starters: Denny Galehouse vs Thornton Lee | Third | 13½ out |
| Friday, July 21 |
| » Defeated Yankees (61-24), 4-1 | Comiskey Park I (31-17) | 48-36 | Won 5 |
| » Starters: Monte Pearson vs Eddie Smith | Third | 12½ out |
| Sunday, July 23 |
| » Defeated Yankees (61-25), 8-5 | Comiskey Park I (32-17) | 49-36 | Won 6 |
| » Starters: Lefty Gomez vs Ted Lyons | Third | 12½ out |
| » Lost to Yankees (62-25), 5-4 | Comiskey Park I (32-18) | 49-37 | |
| » Starters: Bump Hadley vs Johnny Rigney | Third | 12½ out |
| Tuesday, July 25 |
| » Lost to Red Sox (53-30), 3-2 | Fenway Park (2-3) | 49-38 | Lost 2 |
| » Starters: Jack Knott vs Lefty Grove | Third | 14 out |
| » Lost to Red Sox (54-30), 6-5 | Fenway Park (2-4) | 49-39 | Lost 3 |
| » Starters: Johnny Marcum vs Denny Galehouse | Third | 14 out |
| Wednesday, July 26 |
| » Defeated Red Sox (54-31), 8-1 | Fenway Park (3-4) | 50-39 | |
| » Starters: Bill Dietrich vs Jack Wilson | Third | 14½ out |
| » Lost to Red Sox (55-31), 6-5 | Fenway Park (3-5) | 50-40 | |
| » Starters: Thornton Lee vs Fritz Ostermueller | Third | 14½ out |
| Future White Sox Pete Ward is born in Montreal, PQ. |
| Thursday, July 27 |
| » Defeated Red Sox (55-32), 12-7 | Fenway Park (4-5) | 51-40 | |
| » Starters: Johnny Rigney vs Woody Rich | Third | 14 out |
| Friday, July 28 |
| » Lost to Yankees (65-25), 2-1 | Yankee Stadium (0-6) | 51-41 | |
| » Starters: Eddie Smith vs Oral Hildebrand | Third | 15 out |
| Sunday, July 30 |
| » Lost to Yankees (66-25), 4-3 | Yankee Stadium (0-7) | 51-42 | Lost 2 |
| » Starters: Ted Lyons vs Lefty Gomez | Third | 15 out |
| » Defeated Yankees (66-26), 5-1 | Yankee Stadium (1-7) | 52-42 | |
| » Starters: Thornton Lee vs Bump Hadley | Third | 15 out |
| Tuesday, August 1 |
| » Defeated Athletics (34-58), 4-1 | Shibe Park (3-2) | 53-42 | Won 2 |
| » Starters: Jack Knott vs Nels Potter | Third | 14 out |
| Wednesday, August 2 |
| » Lost to Athletics (35-58), 13-4 | Shibe Park (3-3) | 53-43 | |
| » Starters: Bill Dietrich vs Buck Ross | Third | 13½ out |
| » Defeated Athletics (35-59), 2-1 | Shibe Park (4-3) | 54-43 | |
| » Starters: Johnny Rigney vs Lynn Nelson | Third | 13½ out |
| Thursday, August 3 |
| » Defeated Athletics (35-60), 9-7 | Shibe Park (5-3) | 55-43 | Won 2 |
| » Starters: Eddie Smith vs Bill Beckmann | Third | 13½ out |
| Friday, August 4 |
| » Lost to Senators (43-57), 6-5 | Griffith Stadium (4-3) | 55-44 | |
| » Starters: Thornton Lee vs Alex Carrasquel | Third | 14½ out |
| Future White Sox Dennis Higgins is born in Jefferson City, MO. |
| Saturday, August 5 |
| » Lost to Senators (44-57), 10-1 | Griffith Stadium (4-4) | 55-45 | Lost 2 |
| » Starters: Jack Knott vs Ken Chase | Third | 15½ out |
| Sunday, August 6 |
| » Lost to Senators (45-57), 4-3 | Griffith Stadium (4-5) | 55-46 | Lost 3 |
| » Starters: Ted Lyons vs Dutch Leonard | Third | 15 out |
| Tuesday, August 8 |
| » Defeated Tigers (52-49), 5-3 | Tiger Stadium (2-5) | 56-46 | |
| » Starters: Johnny Rigney vs Bobo Newsom | Third | 14 out |
| Wednesday, August 9 |
| » Lost to Tigers (53-49), 10-3 | Tiger Stadium (2-6) | 56-47 | |
| » Starters: Jack Knott vs Schoolboy Rowe | Third | 15 out |
| Future White Sox Claude Osteen is born in Caney Spring, TN. |
| Thursday, August 10 |
| » Lost to Tigers (54-49), 4-3 | Tiger Stadium (2-7) | 56-48 | Lost 2 |
| » Starters: Eddie Smith vs Tommy Bridges | Third | 15 out |
| Saturday, August 12 |
| » Lost to Indians (54-47), 3-2 | Cleveland Stadium (0-2) | 56-49 | Lost 3 |
| » Starters: Bill Dietrich vs Mel Harder | Fourth | 16½ out |
| Sunday, August 13 |
| » Lost to Indians (55-47), 2-0 | Cleveland Stadium (0-3) | 56-50 | Lost 4 |
| » Starters: Ted Lyons vs Bob Feller | Fourth | 16½ out |
| » Defeated Indians (55-48), 3-0 | Cleveland Stadium (1-3) | 57-50 | |
| » Starters: Thornton Lee vs Al Milnar | Fourth | 16½ out |
| Monday, August 14 |
| » Defeated Browns (31-73), 5-2 | Comiskey Park I (33-18) | 58-50 | Won 2 |
| » Starters: Bill Trotter vs Johnny Rigney | Third | 16 out |
| Wednesday, August 16 |
| » Defeated Tigers (57-53), 7-6 | Comiskey Park I (34-18) | 59-50 | Won 3 |
| » Starters: Tommy Bridges vs Bill Dietrich | Third | 16½ out |
| Thursday, August 17 |
| » Defeated Tigers (57-54), 2-1 | Comiskey Park I (35-18) | 60-50 | Won 4 |
| » Starters: Fred Hutchinson vs Jack Knott | Third | 16½ out |
| Friday, August 18 |
| » Defeated Indians (58-52), 1-0 | Comiskey Park I (36-18) | 61-50 | Won 5 |
| » Starters: Bob Feller vs Eddie Smith | Third | 16½ out |
| Saturday, August 19 |
| » Defeated Indians (58-53), 6-5 | Comiskey Park I (37-18) | 62-50 | Won 6 |
| » Starters: Johnny Allen vs Thornton Lee | Third | 16 out |
| Sunday, August 20 |
| » Defeated Indians (58-54), 6-5 | Comiskey Park I (38-18) | 63-50 | Won 7 |
| » Starters: Mel Harder vs Johnny Rigney | Third | 15½ out |
| Tuesday, August 22 |
| » Lost to Yankees (79-34), 14-5 | Comiskey Park I (38-19) | 63-51 | |
| » Starters: Marius Russo vs Bill Dietrich | Third | 16½ out |
| Wednesday, August 23 |
| » Lost to Yankees (80-34), 7-2 | Comiskey Park I (38-20) | 63-52 | Lost 2 |
| » Starters: Atley Donald vs Eddie Smith | Third | 18½ out |
| » Lost to Yankees (81-34), 16-4 | Comiskey Park I (38-21) | 63-53 | Lost 3 |
| » Starters: Red Ruffing vs Thornton Lee | Third | 18½ out |
| Thursday, August 24 |
| » Defeated Red Sox (72-42), 3-1 | Comiskey Park I (39-21) | 64-53 | |
| » Starters: Elden Auker vs Johnny Rigney | Third | 18½ out |
| Friday, August 25 |
| » Defeated Red Sox (72-43), 9-2 | Comiskey Park I (40-21) | 65-53 | Won 2 |
| » Starters: Lefty Grove vs Jack Knott | Third | 19 out |
| Saturday, August 26 |
| » Defeated Red Sox (72-44), 5-4 | Comiskey Park I (41-21) | 66-53 | Won 3 |
| » Starters: Jack Wilson vs Bill Dietrich | Third | 19 out |
| Sunday, August 27 |
| » Lost to Athletics (41-78), 2-0 | Comiskey Park I (41-22) | 66-54 | |
| » Starters: Bill Beckmann vs Thornton Lee | Third | 20 out |
| Monday, August 28 |
| » Defeated Athletics (41-79), 5-4 | Comiskey Park I (42-22) | 67-54 | |
| » Starters: Buck Ross vs Johnny Rigney | Third | 20 out |
| Tuesday, August 29 |
| Future White Sox Dave Nicholson is born in St. Louis, MO. |
| Wednesday, August 30 |
| » Defeated Senators (52-72), 5-2 | Comiskey Park I (43-22) | 68-54 | Won 2 |
| » Starters: Joe Haynes vs Ted Lyons | Third | 19 out |
| » Lost to Senators (53-72), 4-3 | Comiskey Park I (43-23) | 68-55 | |
| » Starters: Joe Krakauskas vs Jack Knott | Third | 19 out |
| Thursday, August 31 |
| » Lost to Senators (54-72), 4-3 | Comiskey Park I (43-24) | 68-56 | Lost 2 |
| » Starters: Dutch Leonard vs Eddie Smith | Third | 19½ out |
| Saturday, September 2 |
| » Defeated Tigers (66-59), 2-0 | Comiskey Park I (44-24) | 69-56 | |
| » Starters: Bobo Newsom vs Johnny Rigney | Third | 19 out |
| Sunday, September 3 |
| » Defeated Tigers (66-60), 8-1 | Comiskey Park I (45-24) | 70-56 | Won 2 |
| » Starters: Al Benton vs Thornton Lee | Third | 18½ out |
| » Lost to Tigers (67-60), 7-2 | Comiskey Park I (45-25) | 70-57 | |
| » Starters: Fred Hutchinson vs Bill Dietrich | Third | 18½ out |
| Monday, September 4 |
| » Defeated Indians (68-58), 5-2 | Cleveland Stadium (2-3) | 71-57 | |
| » Starters: Eddie Smith vs Bob Feller | Third | 19 out |
| Tuesday, September 5 |
| » Defeated Indians (68-59), 4-2 | League Park II (4-2) | 72-57 | Won 2 |
| » Starters: Jack Knott vs Harry Eisenstat | Third | 18½ out |
| Wednesday, September 6 |
| » Defeated Browns (35-91), 7-2 | Sportsman's Park III (6-0) | 73-57 | Won 3 |
| » Starters: Johnny Rigney vs Bill Trotter | Third | 18½ out |
| Thursday, September 7 |
| » Defeated Browns (35-92), 8-4 | Sportsman's Park III (7-0) | 74-57 | Won 4 |
| » Starters: Ted Lyons vs Vern Kennedy | Third | 18 out |
| » Defeated Browns (35-93), 11-4 | Sportsman's Park III (8-0) | 75-57 | Won 5 |
| » Starters: Thornton Lee vs Roxie Lawson | Third | 18 out |
| Friday, September 8 |
| » Major-league debuts: Vern Olsen (Cubs) |
| Sunday, September 10 |
| » Lost to Tigers (70-62), 5-1 | Tiger Stadium (2-8) | 75-58 | |
| » Starters: Johnny Rigney vs Bobo Newsom | Third | 20 out |
| » Defeated Tigers (70-63), 11-9 | Tiger Stadium (3-8) | 76-58 | |
| » Starters: Bill Dietrich vs Schoolboy Rowe | Third | 20 out |
| Tuesday, September 12 |
| » Defeated Senators (59-78), 3-2 | Griffith Stadium (5-5) | 77-58 | Won 2 |
| » Starters: Thornton Lee vs Alex Carrasquel | Third | 19 out |
| Wednesday, September 13 |
| » Defeated Senators (59-79), 3-1 | Griffith Stadium (6-5) | 78-58 | Won 3 |
| » Starters: Ted Lyons vs Ken Chase | Third | 17½ out |
| » Defeated Senators (59-80), 4-2 | Griffith Stadium (7-5) | 79-58 | Won 4 |
| » Starters: Jack Knott vs Early Wynn | Third | 17½ out |
| » Major-league debuts: Al Evans and Early Wynn (Senators) |
| Thursday, September 14 |
| » Lost to Athletics (49-88), 4-2 | Shibe Park (5-4) | 79-59 | |
| » Starters: Eddie Smith vs Nels Potter | Third | 17½ out |
| » Major-league debuts: Bob Kennedy (White Sox) |
| Friday, September 15 |
| » Lost to Athletics (50-88), 3-2 | Shibe Park (5-5) | 79-60 | Lost 2 |
| » Starters: Bill Dietrich vs Lynn Nelson | Third | 18½ out |
| Saturday, September 16 |
| » Lost to Athletics (51-88), 7-6 | Shibe Park (5-6) | 79-61 | Lost 3 |
| » Starters: Johnny Rigney vs Bill Beckmann | Third | 19½ out |
| Sunday, September 17 |
| » Defeated Red Sox (81-59), 6-1 | Fenway Park (5-5) | 80-61 | |
| » Starters: Thornton Lee vs Denny Galehouse | Third | 18½ out |
| » Lost to Red Sox (82-59), 11-7 | Fenway Park (5-6) | 80-62 | |
| » Starters: Jack Knott vs Joe Heving | Third | 18½ out |
| Monday, September 18 |
| » Major-league debuts: Elmer Gedeon (Senators) |
| Tuesday, September 19 |
| » Lost to Yankees (100-43), 6-2 | Yankee Stadium (1-8) | 80-63 | Lost 2 |
| » Starters: Eddie Smith vs Oral Hildebrand | Third | 20 out |
| Wednesday, September 20 |
| » Lost to Yankees (101-43), 8-4 | Yankee Stadium (1-9) | 80-64 | Lost 3 |
| » Starters: Ted Lyons vs Steve Sundra | Fourth | 21 out |
| Thursday, September 21 |
| » Lost to Yankees (102-43), 5-2 | Yankee Stadium (1-10) | 80-65 | Lost 4 |
| » Starters: Bill Dietrich vs Marius Russo | Fourth | 22 out |
| Saturday, September 23 |
| » Defeated Browns (41-103), 6-2 | Comiskey Park I (46-25) | 81-65 | |
| » Starters: Jake Wade vs Johnny Rigney | Fourth | 21½ out |
| » Defeated Browns (41-104), 9-4 | Comiskey Park I (47-25) | 82-65 | Won 2 |
| » Starters: Bill Trotter vs Eddie Smith | Fourth | 21½ out |
| Sunday, September 24 |
| » Defeated Browns (41-105), 11-9 | Comiskey Park I (48-25) | 83-65 | Won 3 |
| » Starters: Bob Harris vs Thornton Lee | Third | 21 out |
| » Defeated Browns (41-106), 4-3 | Comiskey Park I (49-25) | 84-65 | Won 4 |
| » Starters: Bill Cox vs Jack Knott | Third | 21 out |
| Monday, September 25 |
| » Defeated Browns (41-107), 4-3 | Comiskey Park I (50-25) | 85-65 | Won 5 |
| » Starters: Roxie Lawson vs Ted Lyons | Third | 20½ out |
| Wednesday, September 27 |
| » Lost to Indians (83-66), 5-2 | Comiskey Park I (50-26) | 85-66 | |
| » Starters: Harry Eisenstat vs Johnny Rigney | Fourth | 21½ out |
| » Lost to Indians (84-66), 7-5 | Comiskey Park I (50-27) | 85-67 | Lost 2 |
| » Starters: Bob Feller vs Eddie Smith | Fourth | 21½ out |
| Friday, September 29 |
| » Major-league debuts: Hal Newhouser (Tigers) |
| Saturday, September 30 |
| » Lost to Browns (42-110), 5-1 | Sportsman's Park III (8-1) | 85-68 | Lost 3 |
| » Starters: Thornton Lee vs Roxie Lawson | Fourth | 21½ out |
| » Defeated Browns (42-111), 7-5 | Sportsman's Park III (9-1) | 86-68 | |
| » Starters: Jack Knott vs Loy Hanning | Fourth | 21½ out |
| Sunday, October 1 |
| » Lost to Browns (43-111), 4-3 | Sportsman's Park III (9-2) | 86-69 | |
| » Starters: Vallie Eaves vs Emil Bildilli | Fourth | 22 out |
| Monday, October 9 |
| Future White Sox Mike Hershberger is born in Massillon, OH. |
| Tuesday, October 31 |
| Future White Sox Ed Stroud is born in Lapine, AL. |
| Sunday, December 10 |
| Future White Sox Bob Priddy is born in Pittsburgh, PA. |
Game information provided by Retrosheet (www.retrosheet.org) |
