| Saturday, February 11 |
| Future Tiger Willie Smith is born in Anniston, AL. |
| Saturday, February 18 |
| Future Tiger Bob Miller is born in St. Louis, MO. |
| Sunday, February 19 |
| Future Tiger Jackie Moore is born in Jay, FL. |
| Tuesday, April 18 |
| » Defeated White Sox (0-1), 6-1 | Tiger Stadium (1-0) | 1-0 | |
| » Starters: Johnny Rigney vs Tommy Bridges | First | -- |
| » Major-league debuts: Frank Croucher and Barney McCosky (Tigers) Ken Silvestri (White Sox) |
| Thursday, April 20 |
| » Defeated White Sox (0-2), 8-7 | Tiger Stadium (2-0) | 2-0 | Won 2 |
| » Starters: John Whitehead vs Al Benton | First | -- |
| Friday, April 21 |
| » Lost to Indians (1-0), 5-1 | Cleveland Stadium (0-1) | 2-1 | |
| » Starters: Harry Eisenstat vs Bob Feller | Third | ½ out |
| » Major-league debuts: Floyd Giebell (Tigers) |
| Saturday, April 22 |
| » Lost to Indians (2-0), 2-1 | Cleveland Stadium (0-2) | 2-2 | Lost 2 |
| » Starters: Vern Kennedy vs Willis Hudlin | Fourth | 1 out |
| » Major-league debuts: Les Fleming (Tigers) |
| Sunday, April 23 |
| » Defeated Indians (2-1), 8-0 | Cleveland Stadium (1-2) | 3-2 | |
| » Starters: Schoolboy Rowe vs Mel Harder | Third | ½ out |
| Monday, April 24 |
| » Defeated Browns (1-2), 4-2 | Tiger Stadium (3-0) | 4-2 | Won 2 |
| » Starters: Fred Johnson vs Tommy Bridges | Second | ½ out |
| Tuesday, April 25 |
| » Lost to Browns (2-2), 7-2 | Tiger Stadium (3-1) | 4-3 | |
| » Starters: Jack Kramer vs Dizzy Trout | Third | 1½ out |
| » Major-league debuts: Dizzy Trout (Tigers) Jack Kramer (Browns) |
| Wednesday, April 26 |
| » Defeated Browns (2-3), 7-6 | Tiger Stadium (4-1) | 5-3 | |
| » Starters: Bobo Newsom vs Vern Kennedy | Second | 1 out |
| Thursday, April 27 |
| » Lost to White Sox (4-4), 2-1 | Comiskey Park I (0-1) | 5-4 | |
| » Starters: Al Benton vs Jack Knott | Second | 1½ out |
| Saturday, April 29 |
| » Lost to Indians (4-5), 7-1 | Tiger Stadium (4-2) | 5-5 | Lost 2 |
| » Starters: Bob Feller vs Schoolboy Rowe | Fifth | 1½ out |
| Sunday, April 30 |
| » Defeated Indians (4-6), 14-1 | Tiger Stadium (5-2) | 6-5 | |
| » Starters: Joe Dobson vs Tommy Bridges | Fourth | 1½ out |
| Tuesday, May 2 |
| » Lost to Yankees (6-3), 22-2 | Tiger Stadium (5-3) | 6-6 | |
| » Starters: Red Ruffing vs Vern Kennedy | Fifth | 1½ out |
| » Major-league debuts: Fred Hutchinson (Tigers) |
| Future Tiger Gates Brown is born in Crestline, OH. |
| Wednesday, May 3 |
| » Lost to Yankees (7-3), 10-6 | Tiger Stadium (5-4) | 6-7 | Lost 2 |
| » Starters: Steve Sundra vs Al Benton | Fifth | 2½ out |
| Thursday, May 4 |
| » Lost to Red Sox (7-3), 7-6 | Tiger Stadium (5-5) | 6-8 | Lost 3 |
| » Starters: Jim Bagby vs Roxie Lawson | Fifth | 3½ out |
| Friday, May 5 |
| » Lost to Red Sox (8-3), 4-1 | Tiger Stadium (5-6) | 6-9 | Lost 4 |
| » Starters: Woody Rich vs Schoolboy Rowe | Fifth | 4 out |
| Saturday, May 6 |
| » Lost to Red Sox (9-3), 5-4 | Tiger Stadium (5-7) | 6-10 | Lost 5 |
| » Starters: Lefty Grove vs George Gill | Sixth | 5 out |
| Sunday, May 7 |
| » Lost to Athletics (5-10), 10-3 | Tiger Stadium (5-8) | 6-11 | Lost 6 |
| » Starters: George Caster vs Al Benton | Sixth | 5½ out |
| Monday, May 8 |
| » Lost to Athletics (6-10), 6-5 | Tiger Stadium (5-9) | 6-12 | Lost 7 |
| » Starters: Buck Ross vs Bob Harris | Seventh | 5½ out |
| Tuesday, May 9 |
| » Major-league debuts: Bill Crouch (Dodgers) |
| Wednesday, May 10 |
| » Defeated Senators (7-10), 5-1 | Tiger Stadium (6-9) | 7-12 | |
| » Starters: Joe Krakauskas vs Tommy Bridges | Sixth | 5½ out |
| Thursday, May 11 |
| » Lost to Senators (8-10), 4-2 | Tiger Stadium (6-10) | 7-13 | |
| » Starters: Joe Haynes vs Dizzy Trout | Seventh | 7 out |
| Friday, May 12 |
| » Lost to Browns (8-11), 1-0 | Sportsman's Park III (0-1) | 7-14 | Lost 2 |
| » Starters: Al Benton vs Jack Kramer | Eighth | 7½ out |
| Saturday, May 13 |
| » Lost to Browns (9-11), 5-3 | Sportsman's Park III (0-2) | 7-15 | Lost 3 |
| » Starters: Vern Kennedy vs Bobo Newsom | Eighth | 8 out |
| Sunday, May 14 |
| » Defeated Browns (9-12), 14-4 | Sportsman's Park III (1-2) | 8-15 | |
| » Starters: Archie McKain vs Johnny Marcum | Seventh | 7½ out |
| » Defeated Browns (9-13), 7-4 | Sportsman's Park III (2-2) | 9-15 | Won 2 |
| » Starters: Slick Coffman vs Lefty Mills | Seventh | 7½ out |
| Tuesday, May 16 |
| » Defeated Senators (8-13), 6-2 | Griffith Stadium (1-0) | 10-15 | Won 3 |
| » Starters: Tommy Bridges vs Joe Krakauskas | Fifth | 8 out |
| Wednesday, May 17 |
| » Lost to Senators (9-13), 4-1 | Griffith Stadium (1-1) | 10-16 | |
| » Starters: Bobo Newsom vs Walt Masterson | Sixth | 9 out |
| Thursday, May 18 |
| » Lost to Senators (10-13), 3-2 | Griffith Stadium (1-2) | 10-17 | Lost 2 |
| » Starters: Archie McKain vs Alex Carrasquel | Sixth | 10 out |
| Friday, May 19 |
| » Lost to Athletics (8-15), 11-6 | Shibe Park (0-1) | 10-18 | Lost 3 |
| » Starters: Al Benton vs Buck Ross | Sixth | 11 out |
| Saturday, May 20 |
| » Lost to Athletics (9-15), 6-5 | Shibe Park (0-2) | 10-19 | Lost 4 |
| » Starters: Schoolboy Rowe vs Nels Potter | Eighth | 12 out |
| Sunday, May 21 |
| » Lost to Red Sox (16-7), 8-3 | Fenway Park (0-1) | 10-20 | Lost 5 |
| » Starters: Tommy Bridges vs Lefty Grove | Eighth | 13 out |
| Tuesday, May 23 |
| » Defeated Red Sox (16-8), 7-2 | Fenway Park (1-1) | 11-20 | |
| » Starters: Bobo Newsom vs Woody Rich | Seventh | 13 out |
| Wednesday, May 24 |
| » Defeated Yankees (22-6), 6-1 | Yankee Stadium (1-0) | 12-20 | Won 2 |
| » Starters: Dizzy Trout vs Wes Ferrell | Seventh | 12 out |
| Thursday, May 25 |
| » Lost to Yankees (23-6), 5-2 | Yankee Stadium (1-1) | 12-21 | |
| » Starters: Archie McKain vs Red Ruffing | Seventh | 13 out |
| Saturday, May 27 |
| » Defeated Browns (11-22), 12-5 | Tiger Stadium (7-10) | 13-21 | |
| » Starters: Vern Kennedy vs Tommy Bridges | Sixth | 14 out |
| Sunday, May 28 |
| » Defeated Browns (11-23), 6-2 | Tiger Stadium (8-10) | 14-21 | Won 2 |
| » Starters: Jack Kramer vs Bobo Newsom | Fifth | 14 out |
| Monday, May 29 |
| » Defeated Browns (11-24), 10-9 | Tiger Stadium (9-10) | 15-21 | Won 3 |
| » Starters: Roxie Lawson vs Archie McKain | Fifth | 14 out |
| Tuesday, May 30 |
| » Lost to White Sox (19-15), 6-2 | Comiskey Park I (0-2) | 15-22 | |
| » Starters: Schoolboy Rowe vs Ted Lyons | Fifth | 14 out |
| » Defeated White Sox (19-16), 8-3 | Comiskey Park I (1-2) | 16-22 | |
| » Starters: Dizzy Trout vs Jack Knott | Fifth | 14 out |
| Thursday, June 1 |
| » Lost to Red Sox (22-12), 14-5 | Tiger Stadium (9-11) | 16-23 | |
| » Starters: Elden Auker vs Bobo Newsom | Fifth | 15 out |
| Friday, June 2 |
| » Defeated Red Sox (22-13), 8-5 | Tiger Stadium (10-11) | 17-23 | |
| » Starters: Denny Galehouse vs Al Benton | Fifth | 15 out |
| Sunday, June 4 |
| » Lost to Yankees (33-7), 8-4 | Tiger Stadium (10-12) | 17-24 | |
| » Starters: Red Ruffing vs Dizzy Trout | Sixth | 16½ out |
| Monday, June 5 |
| » Defeated Yankees (33-8), 3-0 | Tiger Stadium (11-12) | 18-24 | |
| » Starters: Monte Pearson vs Tommy Bridges | Fifth | 15½ out |
| Tuesday, June 6 |
| » Defeated Yankees (33-9), 6-2 | Tiger Stadium (12-12) | 19-24 | Won 2 |
| » Starters: Oral Hildebrand vs Bobo Newsom | Fifth | 14½ out |
| » Major-league debuts: Marius Russo (Yankees) |
| Wednesday, June 7 |
| » Lost to Athletics (18-25), 5-4 | Tiger Stadium (12-13) | 19-25 | |
| » Starters: Lynn Nelson vs Schoolboy Rowe | Fifth | 15½ out |
| Thursday, June 8 |
| » Defeated Athletics (18-26), 8-4 | Tiger Stadium (13-13) | 20-25 | |
| » Starters: Bill Beckmann vs Dizzy Trout | Fifth | 15½ out |
| Friday, June 9 |
| » Defeated Athletics (18-27), 14-4 | Tiger Stadium (14-13) | 21-25 | Won 2 |
| » Starters: Buck Ross vs Al Benton | Fifth | 15 out |
| Saturday, June 10 |
| » Defeated Senators (18-29), 6-5 | Tiger Stadium (15-13) | 22-25 | Won 3 |
| » Starters: Dutch Leonard vs Tommy Bridges | Fifth | 14 out |
| » Defeated Senators (18-30), 17-5 | Tiger Stadium (16-13) | 23-25 | Won 4 |
| » Starters: Alex Carrasquel vs Harry Eisenstat | Fifth | 14 out |
| Sunday, June 11 |
| » Defeated Senators (18-31), 6-3 | Tiger Stadium (17-13) | 24-25 | Won 5 |
| » Starters: Joe Haynes vs Bobo Newsom | Fifth | 14½ out |
| Wednesday, June 14 |
| » Defeated Red Sox (27-18), 9-8 | Fenway Park (2-1) | 25-25 | Won 6 |
| » Starters: Schoolboy Rowe vs Jim Bagby | Fifth | 13 out |
| » Defeated Red Sox (27-19), 6-2 | Fenway Park (3-1) | 26-25 | Won 7 |
| » Starters: Dizzy Trout vs Denny Galehouse | Fifth | 13 out |
| Thursday, June 15 |
| » Defeated Red Sox (27-20), 6-3 | Fenway Park (4-1) | 27-25 | Won 8 |
| » Starters: Tommy Bridges vs Jack Wilson | Fifth | 13 out |
| Friday, June 16 |
| » Defeated Red Sox (27-21), 8-7 | Fenway Park (5-1) | 28-25 | Won 9 |
| » Starters: Al Benton vs Elden Auker | Fifth | 13 out |
| Saturday, June 17 |
| » Lost to Yankees (40-10), 1-0 | Yankee Stadium (1-2) | 28-26 | |
| » Starters: Bobo Newsom vs Red Ruffing | Fifth | 14 out |
| Sunday, June 18 |
| » Defeated Yankees (40-11), 8-5 | Yankee Stadium (2-2) | 29-26 | |
| » Starters: Schoolboy Rowe vs Bump Hadley | Fourth | 13 out |
| Monday, June 19 |
| » Lost to Yankees (41-11), 8-5 | Yankee Stadium (2-3) | 29-27 | |
| » Starters: Dizzy Trout vs Oral Hildebrand | Fourth | 14 out |
| Tuesday, June 20 |
| » Defeated Athletics (21-33), 5-0 | Shibe Park (1-2) | 30-27 | |
| » Starters: Tommy Bridges vs George Caster | Fourth | 14 out |
| Thursday, June 22 |
| » Lost to Athletics (22-33), 6-5 | Shibe Park (1-3) | 30-28 | |
| » Starters: Bobo Newsom vs Lynn Nelson | Fourth | 15½ out |
| Friday, June 23 |
| » Defeated Senators (23-37), 7-4 | Griffith Stadium (2-2) | 31-28 | |
| » Starters: Al Benton vs Dutch Leonard | Fourth | 15 out |
| Saturday, June 24 |
| » Lost to Senators (24-37), 12-4 | Griffith Stadium (2-3) | 31-29 | |
| » Starters: Schoolboy Rowe vs Alex Carrasquel | Fourth | 16 out |
| Sunday, June 25 |
| » Defeated Senators (24-38), 6-5 | Griffith Stadium (3-3) | 32-29 | |
| » Starters: Archie McKain vs Ken Chase | Fourth | 15½ out |
| Former Tiger Heinie Smith dies in Buffalo, NY at the age of 68. |
| Monday, June 26 |
| » Defeated Indians (32-29), 11-2 | League Park II (1-0) | 33-29 | Won 2 |
| » Starters: Tommy Bridges vs Mel Harder | Third | 14½ out |
| Tuesday, June 27 |
| » Lost to Indians (33-29), 5-0 | Cleveland Stadium (1-3) | 33-30 | |
| » Starters: Bobo Newsom vs Bob Feller | Fourth | 15 out |
| Friday, June 30 |
| » Defeated White Sox (31-30), 3-1 | Tiger Stadium (18-13) | 34-30 | |
| » Starters: Johnny Rigney vs Bobo Newsom | Fourth | 16 out |
| Saturday, July 1 |
| » Defeated White Sox (31-31), 6-5 | Tiger Stadium (19-13) | 35-30 | Won 2 |
| » Starters: Jack Knott vs Al Benton | Fourth | 15½ out |
| » Lost to White Sox (32-31), 4-3 | Tiger Stadium (19-14) | 35-31 | |
| » Starters: Eddie Smith vs Dizzy Trout | Fourth | 15½ out |
| Sunday, July 2 |
| » Defeated White Sox (32-32), 5-1 | Tiger Stadium (20-14) | 36-31 | |
| » Starters: Ted Lyons vs Tommy Bridges | Fourth | 15 out |
| Monday, July 3 |
| » Lost to Indians (36-30), 4-2 | Tiger Stadium (20-15) | 36-32 | |
| » Starters: Bob Feller vs Archie McKain | Fourth | 15½ out |
| Tuesday, July 4 |
| » Defeated Indians (36-31), 4-0 | Tiger Stadium (21-15) | 37-32 | |
| » Starters: Al Milnar vs Bobo Newsom | Fourth | 15 out |
| Thursday, July 6 |
| » Defeated Browns (19-50), 9-5 | Sportsman's Park III (3-2) | 38-32 | Won 2 |
| » Starters: Al Benton vs Lefty Mills | Third | 15 out |
| Friday, July 7 |
| » Lost to Browns (20-50), 8-6 | Sportsman's Park III (3-3) | 38-33 | |
| » Starters: Dizzy Trout vs Jack Kramer | Third | 15 out |
| Saturday, July 8 |
| » Lost to White Sox (38-33), 10-5 | Comiskey Park I (1-3) | 38-34 | Lost 2 |
| » Starters: Tommy Bridges vs Thornton Lee | Fourth | 14½ out |
| Sunday, July 9 |
| » Lost to White Sox (39-33), 4-3 | Comiskey Park I (1-4) | 38-35 | Lost 3 |
| » Starters: Bobo Newsom vs Ted Lyons | Fifth | 14½ out |
| » Lost to White Sox (40-33), 6-3 | Comiskey Park I (1-5) | 38-36 | Lost 4 |
| » Starters: Schoolboy Rowe vs Johnny Rigney | Fifth | 14½ out |
| Thursday, July 13 |
| » Defeated Yankees (53-23), 10-6 | Tiger Stadium (22-15) | 39-36 | |
| » Starters: Atley Donald vs Bobo Newsom | Fifth | 13½ out |
| Friday, July 14 |
| » Lost to Yankees (54-23), 6-3 | Tiger Stadium (22-16) | 39-37 | |
| » Starters: Red Ruffing vs Schoolboy Rowe | Fourth | 14½ out |
| Saturday, July 15 |
| » Lost to Yankees (55-23), 10-7 | Tiger Stadium (22-17) | 39-38 | Lost 2 |
| » Starters: Monte Pearson vs Tommy Bridges | Fifth | 15½ out |
| Sunday, July 16 |
| » Lost to Red Sox (46-25), 9-2 | Tiger Stadium (22-18) | 39-39 | Lost 3 |
| » Starters: Lefty Grove vs Al Benton | Fifth | 17½ out |
| » Lost to Red Sox (47-25), 3-0 | Tiger Stadium (22-19) | 39-40 | Lost 4 |
| » Starters: Denny Galehouse vs Dizzy Trout | Fifth | 17½ out |
| Monday, July 17 |
| » Defeated Red Sox (47-26), 13-6 | Tiger Stadium (23-19) | 40-40 | |
| » Starters: Woody Rich vs Bobo Newsom | Fifth | 17½ out |
| » Major-league debuts: Bill Sayles (Red Sox) |
| Tuesday, July 18 |
| » Lost to Senators (34-50), 10-2 | Tiger Stadium (23-20) | 40-41 | |
| » Starters: Joe Krakauskas vs Tommy Bridges | Fifth | 19 out |
| Wednesday, July 19 |
| » Defeated Senators (34-51), 11-0 | Tiger Stadium (24-20) | 41-41 | |
| » Starters: Ken Chase vs Schoolboy Rowe | Fifth | 18½ out |
| Thursday, July 20 |
| » Lost to Senators (35-51), 8-7 | Tiger Stadium (24-21) | 41-42 | |
| » Starters: Dutch Leonard vs Al Benton | Fifth | 19½ out |
| Friday, July 21 |
| » Lost to Athletics (32-50), 6-2 | Tiger Stadium (24-22) | 41-43 | Lost 2 |
| » Starters: Cotton Pippen vs Dizzy Trout | Fifth | 19½ out |
| Saturday, July 22 |
| » Lost to Athletics (33-50), 4-2 | Tiger Stadium (24-23) | 41-44 | Lost 3 |
| » Starters: Lynn Nelson vs Bobo Newsom | Fifth | 19½ out |
| » Defeated Athletics (33-51), 11-10 | Tiger Stadium (25-23) | 42-44 | |
| » Starters: Nels Potter vs Schoolboy Rowe | Fifth | 19½ out |
| Sunday, July 23 |
| » Defeated Athletics (33-52), 16-3 | Tiger Stadium (26-23) | 43-44 | Won 2 |
| » Starters: Buck Ross vs Tommy Bridges | Fifth | 19 out |
| » Major-league debuts: Harry O'Neill (Athletics) |
| Tuesday, July 25 |
| » Lost to Senators (37-54), 5-3 | Griffith Stadium (3-4) | 43-45 | |
| » Starters: Fred Hutchinson vs Dutch Leonard | Fifth | 20 out |
| Wednesday, July 26 |
| » Defeated Senators (37-55), 3-1 | Griffith Stadium (4-4) | 44-45 | |
| » Starters: Bobo Newsom vs Joe Krakauskas | Fifth | 20 out |
| Thursday, July 27 |
| » Defeated Senators (37-56), 8-1 | Griffith Stadium (5-4) | 45-45 | Won 2 |
| » Starters: Dizzy Trout vs Walt Masterson | Fifth | 19½ out |
| Friday, July 28 |
| » Lost to Athletics (34-54), 3-0 | Shibe Park (1-4) | 45-46 | |
| » Starters: Schoolboy Rowe vs Buck Ross | Fifth | 20½ out |
| Saturday, July 29 |
| » Defeated Athletics (34-55), 7-6 | Shibe Park (2-4) | 46-46 | |
| » Starters: Tommy Bridges vs Lynn Nelson | Fifth | 20 out |
| Sunday, July 30 |
| » Defeated Athletics (34-56), 14-0 | Shibe Park (3-4) | 47-46 | Won 2 |
| » Starters: Bobo Newsom vs Bill Beckmann | Fifth | 19 out |
| » Defeated Athletics (34-57), 5-3 | Shibe Park (4-4) | 48-46 | Won 3 |
| » Starters: Fred Hutchinson vs Cotton Pippen | Fifth | 19 out |
| Tuesday, August 1 |
| » Defeated Yankees (66-27), 5-2 | Yankee Stadium (3-3) | 49-46 | Won 4 |
| » Starters: Dizzy Trout vs Red Ruffing | Fifth | 18 out |
| Wednesday, August 2 |
| » Defeated Yankees (66-28), 7-2 | Yankee Stadium (4-3) | 50-46 | Won 5 |
| » Starters: Schoolboy Rowe vs Atley Donald | Fifth | 17 out |
| Thursday, August 3 |
| » Lost to Yankees (67-28), 12-3 | Yankee Stadium (4-4) | 50-47 | |
| » Starters: Bobo Newsom vs Monte Pearson | Fifth | 18 out |
| Saturday, August 5 |
| » Defeated Red Sox (59-36), 16-4 | Fenway Park (6-1) | 51-47 | |
| » Starters: Tommy Bridges vs Elden Auker | Fourth | 18½ out |
| Sunday, August 6 |
| » Defeated Red Sox (59-37), 10-1 | Fenway Park (7-1) | 52-47 | Won 2 |
| » Starters: Fred Hutchinson vs Denny Galehouse | Fourth | 17½ out |
| » Lost to Red Sox (60-37), 8-3 | Fenway Park (7-2) | 52-48 | |
| » Starters: Dizzy Trout vs Jack Wilson | Fourth | 17½ out |
| Tuesday, August 8 |
| » Lost to White Sox (56-46), 5-3 | Tiger Stadium (26-24) | 52-49 | Lost 2 |
| » Starters: Johnny Rigney vs Bobo Newsom | Fifth | 17½ out |
| Wednesday, August 9 |
| » Defeated White Sox (56-47), 10-3 | Tiger Stadium (27-24) | 53-49 | |
| » Starters: Jack Knott vs Schoolboy Rowe | Fifth | 17½ out |
| Thursday, August 10 |
| » Defeated White Sox (56-48), 4-3 | Tiger Stadium (28-24) | 54-49 | Won 2 |
| » Starters: Eddie Smith vs Tommy Bridges | Fifth | 16½ out |
| Friday, August 11 |
| » Defeated Browns (29-72), 4-3 | Tiger Stadium (29-24) | 55-49 | Won 3 |
| » Starters: Bob Harris vs Bobo Newsom | Fifth | 16½ out |
| Saturday, August 12 |
| » Lost to Browns (30-72), 17-3 | Tiger Stadium (29-25) | 55-50 | |
| » Starters: Vern Kennedy vs Fred Hutchinson | Fifth | 17½ out |
| Sunday, August 13 |
| » Lost to Browns (31-72), 11-7 | Tiger Stadium (29-26) | 55-51 | Lost 2 |
| » Starters: Jack Kramer vs Dizzy Trout | Fifth | 18 out |
| Monday, August 14 |
| » Lost to Indians (56-48), 8-4 | Tiger Stadium (29-27) | 55-52 | Lost 3 |
| » Starters: Johnny Allen vs Archie McKain | Fifth | 18 out |
| » Defeated Indians (56-49), 10-3 | Tiger Stadium (30-27) | 56-52 | |
| » Starters: Willis Hudlin vs Schoolboy Rowe | Fifth | 18 out |
| Tuesday, August 15 |
| » Defeated Indians (56-50), 12-3 | Tiger Stadium (31-27) | 57-52 | Won 2 |
| » Starters: Joe Dobson vs Bobo Newsom | Fifth | 18 out |
| Wednesday, August 16 |
| » Lost to White Sox (59-50), 7-6 | Comiskey Park I (1-6) | 57-53 | |
| » Starters: Tommy Bridges vs Bill Dietrich | Fifth | 19 out |
| Thursday, August 17 |
| » Lost to White Sox (60-50), 2-1 | Comiskey Park I (1-7) | 57-54 | Lost 2 |
| » Starters: Fred Hutchinson vs Jack Knott | Fifth | 20 out |
| Saturday, August 19 |
| » Defeated Browns (32-76), 9-3 | Sportsman's Park III (4-3) | 58-54 | |
| » Starters: Schoolboy Rowe vs Jack Kramer | Fifth | 20 out |
| Sunday, August 20 |
| » Lost to Browns (33-76), 6-2 | Sportsman's Park III (4-4) | 58-55 | |
| » Starters: Bobo Newsom vs Vern Kennedy | Fifth | 20½ out |
| Tuesday, August 22 |
| » Defeated Athletics (39-74), 9-4 | Tiger Stadium (32-27) | 59-55 | |
| » Starters: Bill Beckmann vs Tommy Bridges | Fifth | 20½ out |
| Wednesday, August 23 |
| » Lost to Athletics (40-74), 7-6 | Tiger Stadium (32-28) | 59-56 | |
| » Starters: Cotton Pippen vs Fred Hutchinson | Fifth | 22 out |
| Thursday, August 24 |
| » Defeated Senators (50-68), 8-1 | Tiger Stadium (33-28) | 60-56 | |
| » Starters: Dutch Leonard vs Dizzy Trout | Fifth | 22 out |
| Friday, August 25 |
| » Defeated Senators (50-69), 5-2 | Tiger Stadium (34-28) | 61-56 | Won 2 |
| » Starters: Joe Haynes vs Bobo Newsom | Fifth | 22½ out |
| Saturday, August 26 |
| » Defeated Senators (50-70), 6-3 | Tiger Stadium (35-28) | 62-56 | Won 3 |
| » Starters: Joe Krakauskas vs Archie McKain | Fifth | 22½ out |
| Sunday, August 27 |
| » Lost to Yankees (86-34), 13-3 | Tiger Stadium (35-29) | 62-57 | |
| » Starters: Red Ruffing vs Schoolboy Rowe | Fifth | 23½ out |
| Monday, August 28 |
| » Lost to Yankees (87-34), 18-2 | Tiger Stadium (35-30) | 62-58 | Lost 2 |
| » Starters: Marius Russo vs Tommy Bridges | Fifth | 24½ out |
| Tuesday, August 29 |
| » Defeated Yankees (87-35), 7-6 | Tiger Stadium (36-30) | 63-58 | |
| » Starters: Atley Donald vs Bobo Newsom | Fifth | 23½ out |
| Wednesday, August 30 |
| » Defeated Red Sox (74-47), 7-6 | Tiger Stadium (37-30) | 64-58 | Won 2 |
| » Starters: Jack Wilson vs Fred Hutchinson | Fifth | 22½ out |
| Thursday, August 31 |
| » Defeated Red Sox (74-48), 11-4 | Tiger Stadium (38-30) | 65-58 | Won 3 |
| » Starters: Lefty Grove vs Dizzy Trout | Fifth | 22 out |
| Friday, September 1 |
| » Defeated Red Sox (74-49), 14-10 | Tiger Stadium (39-30) | 66-58 | Won 4 |
| » Starters: Elden Auker vs Schoolboy Rowe | Fifth | 22 out |
| Saturday, September 2 |
| » Lost to White Sox (69-56), 2-0 | Comiskey Park I (1-8) | 66-59 | |
| » Starters: Bobo Newsom vs Johnny Rigney | Fifth | 22 out |
| Sunday, September 3 |
| » Lost to White Sox (70-56), 8-1 | Comiskey Park I (1-9) | 66-60 | Lost 2 |
| » Starters: Al Benton vs Thornton Lee | Fifth | 21½ out |
| » Defeated White Sox (70-57), 7-2 | Comiskey Park I (2-9) | 67-60 | |
| » Starters: Fred Hutchinson vs Bill Dietrich | Fifth | 21½ out |
| Monday, September 4 |
| » Lost to Browns (35-89), 3-2 | Tiger Stadium (39-31) | 67-61 | |
| » Starters: Bob Harris vs Dizzy Trout | Fifth | 23 out |
| » Tied Browns, 5-5 | Tiger Stadium (39-31) | 67-61 | |
| » Starters: Jack Kramer vs Schoolboy Rowe | Fifth | 23 out |
| Tuesday, September 5 |
| » Defeated Browns (35-90), 4-2 | Tiger Stadium (40-31) | 68-61 | |
| » Starters: George Gill vs Al Benton | Fifth | 22½ out |
| Wednesday, September 6 |
| » Defeated Indians (68-60), 2-0 | League Park II (2-0) | 69-61 | Won 2 |
| » Starters: Archie McKain vs Al Milnar | Fourth | 22½ out |
| Thursday, September 7 |
| » Lost to Indians (69-60), 9-8 | League Park II (2-1) | 69-62 | |
| » Starters: Fred Hutchinson vs Mel Harder | Fifth | 23½ out |
| Friday, September 8 |
| » Major-league debuts: Vern Olsen (Cubs) |
| Sunday, September 10 |
| » Defeated White Sox (75-58), 5-1 | Tiger Stadium (41-31) | 70-62 | |
| » Starters: Johnny Rigney vs Bobo Newsom | Fifth | 25½ out |
| » Lost to White Sox (76-58), 11-9 | Tiger Stadium (41-32) | 70-63 | |
| » Starters: Bill Dietrich vs Schoolboy Rowe | Fifth | 25½ out |
| Tuesday, September 12 |
| » Lost to Red Sox (80-55), 2-1 | Fenway Park (7-3) | 70-64 | Lost 2 |
| » Starters: Tommy Bridges vs Denny Galehouse | Fifth | 25½ out |
| Wednesday, September 13 |
| » Lost to Red Sox (81-55), 1-0 | Fenway Park (7-4) | 70-65 | Lost 3 |
| » Starters: Fred Hutchinson vs Lefty Grove | Fifth | 25½ out |
| Thursday, September 14 |
| » Defeated Yankees (96-41), 6-1 | Yankee Stadium (5-4) | 71-65 | |
| » Starters: Bobo Newsom vs Atley Donald | Fifth | 24½ out |
| Friday, September 15 |
| » Lost to Yankees (97-41), 10-3 | Yankee Stadium (5-5) | 71-66 | |
| » Starters: Schoolboy Rowe vs Steve Sundra | Fifth | 25½ out |
| Saturday, September 16 |
| » Lost to Yankees (98-41), 8-5 | Yankee Stadium (5-6) | 71-67 | Lost 2 |
| » Starters: Cotton Pippen vs Marius Russo | Fifth | 26½ out |
| Sunday, September 17 |
| » Defeated Senators (61-82), 3-2 | Griffith Stadium (6-4) | 72-67 | |
| » Starters: Dizzy Trout vs Ken Chase | Fifth | 25 out |
| Monday, September 18 |
| » Lost to Senators (62-82), 4-2 | Griffith Stadium (6-5) | 72-68 | |
| » Starters: Tommy Bridges vs Dutch Leonard | Fifth | 26 out |
| » Major-league debuts: Elmer Gedeon (Senators) |
| Tuesday, September 19 |
| » Defeated Athletics (52-91), 8-4 | Shibe Park (5-4) | 73-68 | |
| » Starters: Bobo Newsom vs Nels Potter | Fifth | 26 out |
| Wednesday, September 20 |
| » Lost to Athletics (53-91), 5-4 | Shibe Park (5-5) | 73-69 | |
| » Starters: Fred Hutchinson vs Lynn Nelson | Fifth | 27 out |
| Thursday, September 21 |
| » Defeated Athletics (53-92), 7-6 | Shibe Park (6-5) | 74-69 | |
| » Starters: Cotton Pippen vs Bill Beckmann | Fifth | 27 out |
| Friday, September 22 |
| » Lost to Indians (82-63), 5-4 | League Park II (2-2) | 74-70 | |
| » Starters: Archie McKain vs Bob Feller | Fifth | 27½ out |
| Saturday, September 23 |
| » Defeated Indians (82-64), 6-3 | League Park II (3-2) | 75-70 | |
| » Starters: Bobo Newsom vs Johnny Allen | Fifth | 27½ out |
| Sunday, September 24 |
| » Defeated Indians (82-65), 2-1 | League Park II (4-2) | 76-70 | Won 2 |
| » Starters: Tommy Bridges vs Mel Harder | Fifth | 27 out |
| » Defeated Indians (82-66), 9-1 | League Park II (5-2) | 77-70 | Won 3 |
| » Starters: Dizzy Trout vs Al Milnar | Fifth | 27 out |
| Tuesday, September 26 |
| » Defeated Browns (41-108), 5-4 | Sportsman's Park III (5-4) | 78-70 | Won 4 |
| » Starters: Fred Hutchinson vs Emil Bildilli | Fifth | 26 out |
| » Defeated Browns (41-109), 7-5 | Sportsman's Park III (6-4) | 79-70 | Won 5 |
| » Starters: Schoolboy Rowe vs Jack Kramer | Fifth | 26 out |
| Wednesday, September 27 |
| » Defeated Browns (41-110), 7-4 | Sportsman's Park III (7-4) | 80-70 | Won 6 |
| » Starters: Bobo Newsom vs Bill Cox | Fifth | 25½ out |
| Friday, September 29 |
| » Lost to Indians (85-66), 4-3 | Tiger Stadium (41-33) | 80-71 | |
| » Starters: Mel Harder vs Archie McKain | Fifth | 26½ out |
| » Lost to Indians (86-66), 3-0 | Tiger Stadium (41-34) | 80-72 | Lost 2 |
| » Starters: Al Milnar vs Hal Newhouser | Fifth | 26½ out |
| » Major-league debuts: Hal Newhouser (Tigers) |
| Saturday, September 30 |
| » Major-league debuts: Murry Dickson (Cardinals) |
| Sunday, October 1 |
| » Lost to Indians (87-66), 8-3 | Tiger Stadium (41-35) | 80-73 | Lost 3 |
| » Starters: Bob Feller vs Dizzy Trout | Fifth | 26½ out |
| » Defeated Indians (87-67), 1-0 | Tiger Stadium (42-35) | 81-73 | |
| » Starters: Mike Naymick vs Bobo Newsom | Fifth | 26½ out |
| Thursday, October 19 |
| Former Tiger Red Downs dies in Council Bluffs, IA at the age of 57. |
| Friday, November 24</ |
