| Tuesday, February 7 |
| Future Senator Frank Kreutzer is born in Buffalo, NY. |
| Saturday, March 18 |
| Former Senator Ralph Miller dies in Ft.Wayne, IN at the age of 44. |
| Thursday, March 23 |
| Future Senator Sam Bowens is born in Wilmington, NC. |
| Sunday, April 16 |
| Future Senator Bernie Allen is born in East Liverpool, OH. |
| Tuesday, April 18 |
| » Major-league debuts: Frank Croucher and Barney McCosky (Tigers) Ken Silvestri (White Sox) |
| Wednesday, April 19 |
| » Major-league debuts: Ralph Hodgin (Braves) |
| Thursday, April 20 |
| » Lost to Athletics (1-0), 2-0 | Shibe Park (0-1) | 0-1 | |
| » Starters: Jimmie DeShong vs George Caster | Fourth | 1½ out |
| Friday, April 21 |
| » Lost to Yankees (2-0), 6-3 | Griffith Stadium (0-1) | 0-2 | Lost 2 |
| » Starters: Lefty Gomez vs Joe Krakauskas | Sixth | 2 out |
| Saturday, April 22 |
| » Defeated Yankees (2-1), 3-1 | Griffith Stadium (1-1) | 1-2 | |
| » Starters: Oral Hildebrand vs Dutch Leonard | Fifth | 1½ out |
| » Major-league debuts: Charlie Keller (Yankees) |
| Sunday, April 23 |
| » Lost to Yankees (3-1), 7-4 | Griffith Stadium (1-2) | 1-3 | |
| » Starters: Steve Sundra vs Ken Chase | Sixth | 2 out |
| » Major-league debuts: Alex Carrasquel (Senators) |
| Monday, April 24 |
| » Defeated Red Sox (2-3), 10-9 | Fenway Park (1-0) | 2-3 | |
| » Starters: Jimmie DeShong vs Jack Wilson | Fourth | 2 out |
| » Major-league debuts: Joe Haynes (Senators) |
| Tuesday, April 25 |
| » Lost to Red Sox (3-3), 6-5 | Fenway Park (1-1) | 2-4 | |
| » Starters: Joe Krakauskas vs Fritz Ostermueller | Sixth | 3 out |
| Wednesday, April 26 |
| » Major-league debuts: Joe Dobson (Indians) |
| Thursday, April 27 |
| » Defeated Athletics (2-5), 6-3 | Griffith Stadium (2-2) | 3-4 | |
| » Starters: George Caster vs Dutch Leonard | Fifth | 2½ out |
| Saturday, April 29 |
| » Defeated Yankees (5-2), 3-1 | Yankee Stadium (1-0) | 4-4 | Won 2 |
| » Starters: Ken Chase vs Lefty Gomez | Fourth | 1½ out |
| » Major-league debuts: Buddy Rosar (Yankees) |
| Sunday, April 30 |
| » Defeated Yankees (5-3), 3-2 | Yankee Stadium (2-0) | 5-4 | Won 3 |
| » Starters: Joe Krakauskas vs Oral Hildebrand | Third | ½ out |
| Monday, May 1 |
| » Major-league debuts: Dave Coble (Phillies) |
| Tuesday, May 2 |
| » Defeated Browns (4-6), 9-7 | Sportsman's Park III (1-0) | 6-4 | Won 4 |
| » Starters: Jimmie DeShong vs Russ Van Atta | Fourth | ½ out |
| » Major-league debuts: Johnny Welaj (Senators) |
| Wednesday, May 3 |
| » Defeated Browns (4-7), 11-10 | Sportsman's Park III (2-0) | 7-4 | Won 5 |
| » Starters: Dutch Leonard vs Bobo Newsom | Third | ½ out |
| Thursday, May 4 |
| » Lost to White Sox (8-5), 4-3 | Comiskey Park I (0-1) | 7-5 | |
| » Starters: Ken Chase vs Johnny Rigney | Fourth | 1½ out |
| » Major-league debuts: Jake Early (Senators) |
| Friday, May 5 |
| » Lost to White Sox (9-5), 2-1 | Comiskey Park I (0-2) | 7-6 | Lost 2 |
| » Starters: Joe Krakauskas vs Thornton Lee | Fourth | 2 out |
| Saturday, May 6 |
| » Lost to White Sox (10-5), 14-12 | Comiskey Park I (0-3) | 7-7 | Lost 3 |
| » Starters: Jimmie DeShong vs Jack Knott | Fourth | 3 out |
| Sunday, May 7 |
| » Lost to Indians (6-9), 8-7 | Cleveland Stadium (0-1) | 7-8 | Lost 4 |
| » Starters: Dutch Leonard vs Johnny Allen | Fourth | 3½ out |
| Monday, May 8 |
| » Lost to Indians (7-9), 6-2 | League Park II (0-1) | 7-9 | Lost 5 |
| » Starters: Ken Chase vs Willis Hudlin | Fifth | 3½ out |
| » Major-league debuts: Walt Masterson (Senators) |
| Wednesday, May 10 |
| » Lost to Tigers (7-12), 5-1 | Tiger Stadium (0-1) | 7-10 | Lost 6 |
| » Starters: Joe Krakauskas vs Tommy Bridges | Fifth | 4½ out |
| Thursday, May 11 |
| » Defeated Tigers (7-13), 4-2 | Tiger Stadium (1-1) | 8-10 | |
| » Starters: Joe Haynes vs Dizzy Trout | Fifth | 5 out |
| Sunday, May 14 |
| » Lost to Red Sox (11-5), 5-4 | Griffith Stadium (2-3) | 8-11 | |
| » Starters: Lefty Grove vs Alex Carrasquel | Fifth | 6 out |
| Monday, May 15 |
| » Lost to Red Sox (12-5), 9-2 | Griffith Stadium (2-4) | 8-12 | Lost 2 |
| » Starters: Fritz Ostermueller vs Ken Chase | Sixth | 7 out |
| Tuesday, May 16 |
| » Lost to Tigers (10-15), 6-2 | Griffith Stadium (2-5) | 8-13 | Lost 3 |
| » Starters: Tommy Bridges vs Joe Krakauskas | Seventh | 8 out |
| Wednesday, May 17 |
| » Defeated Tigers (10-16), 4-1 | Griffith Stadium (3-5) | 9-13 | |
| » Starters: Bobo Newsom vs Walt Masterson | Fifth | 8 out |
| Thursday, May 18 |
| » Defeated Tigers (10-17), 3-2 | Griffith Stadium (4-5) | 10-13 | Won 2 |
| » Starters: Archie McKain vs Alex Carrasquel | Fifth | 8 out |
| Friday, May 19 |
| » Lost to Indians (13-11), 8-4 | Griffith Stadium (4-6) | 10-14 | |
| » Starters: Willis Hudlin vs Ken Chase | Fifth | 9 out |
| Saturday, May 20 |
| » Defeated Indians (13-12), 6-3 | Griffith Stadium (5-6) | 11-14 | |
| » Starters: Bob Feller vs Dutch Leonard | Fifth | 9 out |
| Sunday, May 21 |
| » Lost to White Sox (15-13), 3-2 | Griffith Stadium (5-7) | 11-15 | |
| » Starters: Ted Lyons vs Joe Krakauskas | Fifth | 10 out |
| Tuesday, May 23 |
| » Lost to White Sox (16-13), 5-4 | Griffith Stadium (5-8) | 11-16 | Lost 2 |
| » Starters: Jack Knott vs Joe Haynes | Fifth | 11 out |
| Wednesday, May 24 |
| » Defeated Browns (11-20), 16-6 | Griffith Stadium (6-8) | 12-16 | |
| » Starters: Jack Kramer vs Walt Masterson | Fifth | 10 out |
| Future Senator Jim Duckworth is born in National City, CA. Former Senator Barney Pelty dies in Farmington, MO at the age of 59 |
| Thursday, May 25 |
| » Defeated Browns (11-21), 4-1 | Griffith Stadium (7-8) | 13-16 | Won 2 |
| » Starters: Roxie Lawson vs Alex Carrasquel | Fifth | 10 out |
| Friday, May 26 |
| » Lost to Red Sox (17-10), 4-2 | Fenway Park (1-2) | 13-17 | |
| » Starters: Dutch Leonard vs Woody Rich | Fifth | 11 out |
| Saturday, May 27 |
| » Lost to Red Sox (18-10), 11-4 | Fenway Park (1-3) | 13-18 | Lost 2 |
| » Starters: Jimmie DeShong vs Lefty Grove | Fifth | 13 out |
| » Lost to Red Sox (19-10), 7-6 | Fenway Park (1-4) | 13-19 | Lost 3 |
| » Starters: Joe Krakauskas vs Elden Auker | Fifth | 13 out |
| Sunday, May 28 |
| » Lost to Red Sox (20-10), 12-7 | Fenway Park (1-5) | 13-20 | Lost 4 |
| » Starters: Joe Haynes vs Fritz Ostermueller | Sixth | 14 out |
| Monday, May 29 |
| » Lost to Athletics (12-21), 5-4 | Griffith Stadium (7-9) | 13-21 | Lost 5 |
| » Starters: Buck Ross vs Joe Krakauskas | Sixth | 15 out |
| Tuesday, May 30 |
| » Lost to Athletics (13-21), 3-1 | Griffith Stadium (7-10) | 13-22 | Lost 6 |
| » Starters: Nels Potter vs Alex Carrasquel | Sixth | 15 out |
| » Defeated Athletics (13-22), 8-4 | Griffith Stadium (8-10) | 14-22 | |
| » Starters: Cotton Pippen vs Ken Chase | Sixth | 15 out |
| Thursday, June 1 |
| » Defeated White Sox (19-17), 10-7 | Comiskey Park I (1-3) | 15-22 | Won 2 |
| » Starters: Dutch Leonard vs Eddie Smith | Sixth | 15 out |
| Friday, June 2 |
| » Lost to White Sox (20-17), 7-5 | Comiskey Park I (1-4) | 15-23 | |
| » Starters: Joe Haynes vs Thornton Lee | Sixth | 16 out |
| Saturday, June 3 |
| » Lost to White Sox (21-17), 8-7 | Comiskey Park I (1-5) | 15-24 | Lost 2 |
| » Starters: Alex Carrasquel vs Johnny Rigney | Seventh | 17 out |
| Sunday, June 4 |
| » Lost to Browns (12-29), 5-4 | Sportsman's Park III (2-1) | 15-25 | Lost 3 |
| » Starters: Ken Chase vs Jack Kramer | Seventh | 18½ out |
| » Lost to Browns (13-29), 11-3 | Sportsman's Park III (2-2) | 15-26 | Lost 4 |
| » Starters: Jimmie DeShong vs Vern Kennedy | Seventh | 18½ out |
| Tuesday, June 6 |
| » Defeated Browns (13-30), 10-7 | Sportsman's Park III (3-2) | 16-26 | |
| » Starters: Dutch Leonard vs Roxie Lawson | Seventh | 17 out |
| Wednesday, June 7 |
| » Defeated Indians (22-20), 10-4 | League Park II (1-1) | 17-26 | Won 2 |
| » Starters: Joe Haynes vs Al Milnar | Seventh | 16½ out |
| » Defeated Indians (22-21), 13-9 | League Park II (2-1) | 18-26 | Won 3 |
| » Starters: Alex Carrasquel vs Joe Dobson | Seventh | 16½ out |
| Thursday, June 8 |
| » Lost to Indians (23-21), 7-5 | League Park II (2-2) | 18-27 | |
| » Starters: Joe Krakauskas vs Mel Harder | Seventh | 17½ out |
| Friday, June 9 |
| » Lost to Indians (24-21), 3-2 | League Park II (2-3) | 18-28 | Lost 2 |
| » Starters: Ken Chase vs Bob Feller | Seventh | 18 out |
| Saturday, June 10 |
| » Lost to Tigers (22-25), 6-5 | Tiger Stadium (1-2) | 18-29 | Lost 3 |
| » Starters: Dutch Leonard vs Tommy Bridges | Seventh | 19 out |
| » Lost to Tigers (23-25), 17-5 | Tiger Stadium (1-3) | 18-30 | Lost 4 |
| » Starters: Alex Carrasquel vs Harry Eisenstat | Seventh | 19 out |
| Sunday, June 11 |
| » Lost to Tigers (24-25), 6-3 | Tiger Stadium (1-4) | 18-31 | Lost 5 |
| » Starters: Joe Haynes vs Bobo Newsom | Seventh | 20½ out |
| Wednesday, June 14 |
| » Defeated White Sox (25-22), 3-0 | Griffith Stadium (9-10) | 19-31 | |
| » Starters: Johnny Rigney vs Dutch Leonard | Sixth | 19½ out |
| Thursday, June 15 |
| » Lost to White Sox (26-22), 5-1 | Griffith Stadium (9-11) | 19-32 | |
| » Starters: Jack Knott vs Joe Haynes | Seventh | 21 out |
| » Lost to White Sox (27-22), 4-2 | Griffith Stadium (9-12) | 19-33 | Lost 2 |
| » Starters: Thornton Lee vs Ken Chase | Seventh | 21 out |
| Friday, June 16 |
| » Defeated White Sox (27-23), 5-2 | Griffith Stadium (10-12) | 20-33 | |
| » Starters: Vic Frasier vs Harry Kelley | Seventh | 21 out |
| Saturday, June 17 |
| » Defeated Browns (14-37), 4-3 | Griffith Stadium (11-12) | 21-33 | Won 2 |
| » Starters: Lefty Mills vs Alex Carrasquel | Seventh | 21 out |
| Monday, June 19 |
| » Lost to Browns (15-37), 2-1 | Griffith Stadium (11-13) | 21-34 | |
| » Starters: Vern Kennedy vs Dutch Leonard | Sixth | 21 out |
| » Defeated Browns (15-38), 6-1 | Griffith Stadium (12-13) | 22-34 | |
| » Starters: Roxie Lawson vs Joe Krakauskas | Sixth | 21 out |
| Tuesday, June 20 |
| » Lost to Indians (29-25), 4-3 | Griffith Stadium (12-14) | 22-35 | |
| » Starters: Johnny Allen vs Ken Chase | Seventh | 22 out |
| Wednesday, June 21 |
| » Lost to Indians (30-25), 9-8 | Griffith Stadium (12-15) | 22-36 | Lost 2 |
| » Starters: Mel Harder vs Joe Haynes | Seventh | 23 out |
| Thursday, June 22 |
| » Defeated Indians (30-26), 8-5 | Griffith Stadium (13-15) | 23-36 | |
| » Starters: Al Milnar vs Harry Kelley | Seventh | 23 out |
| Friday, June 23 |
| » Lost to Tigers (31-28), 7-4 | Griffith Stadium (13-16) | 23-37 | |
| » Starters: Al Benton vs Dutch Leonard | Seventh | 23½ out |
| Saturday, June 24 |
| » Defeated Tigers (31-29), 12-4 | Griffith Stadium (14-16) | 24-37 | |
| » Starters: Schoolboy Rowe vs Alex Carrasquel | Seventh | 23½ out |
| Sunday, June 25 |
| » Lost to Tigers (32-29), 6-5 | Griffith Stadium (14-17) | 24-38 | |
| » Starters: Archie McKain vs Ken Chase | Seventh | 24 out |
| Monday, June 26 |
| » Lost to Red Sox (32-23), 3-0 | Griffith Stadium (14-18) | 24-39 | Lost 2 |
| » Starters: Lefty Grove vs Joe Haynes | Seventh | 24 out |
| Tuesday, June 27 |
| » Lost to Red Sox (33-23), 8-0 | Griffith Stadium (14-19) | 24-40 | Lost 3 |
| » Starters: Elden Auker vs Harry Kelley | Seventh | 24½ out |
| Thursday, June 29 |
| » Defeated Yankees (48-14), 2-1 | Griffith Stadium (15-19) | 25-40 | |
| » Starters: Red Ruffing vs Dutch Leonard | Seventh | 25½ out |
| » Lost to Yankees (49-14), 7-0 | Griffith Stadium (15-20) | 25-41 | |
| » Starters: Atley Donald vs Ken Chase | Seventh | 25½ out |
| Friday, June 30 |
| » Lost to Yankees (50-14), 10-2 | Griffith Stadium (15-21) | 25-42 | Lost 2 |
| » Starters: Oral Hildebrand vs Alex Carrasquel | Seventh | 26½ out |
| Saturday, July 1 |
| » Defeated Athletics (26-38), 9-4 | Griffith Stadium (16-21) | 26-42 | |
| » Starters: Buck Ross vs Joe Haynes | Seventh | 25½ out |
| Sunday, July 2 |
| » Defeated Athletics (26-39), 4-3 | Griffith Stadium (17-21) | 27-42 | Won 2 |
| » Starters: Bill Beckmann vs Walt Masterson | Sixth | 24½ out |
| » Defeated Athletics (26-40), 13-2 | Griffith Stadium (18-21) | 28-42 | Won 3 |
| » Starters: Chubby Dean vs Joe Krakauskas | Sixth | 24½ out |
| Tuesday, July 4 |
| » Defeated Yankees (51-17), 3-2 | Yankee Stadium (3-0) | 29-42 | Won 4 |
| » Starters: Dutch Leonard vs Monte Pearson | Sixth | 24½ out |
| » Lost to Yankees (52-17), 11-1 | Yankee Stadium (3-1) | 29-43 | |
| » Starters: Alex Carrasquel vs Steve Sundra | Sixth | 24½ out |
| Wednesday, July 5 |
| » Lost to Yankees (53-17), 6-4 | Yankee Stadium (3-2) | 29-44 | Lost 2 |
| » Starters: Ken Chase vs Atley Donald | Fifth | 25½ out |
| Thursday, July 6 |
| » Lost to Athletics (27-43), 9-3 | Shibe Park (0-2) | 29-45 | Lost 3 |
| » Starters: Joe Haynes vs George Caster | Sixth | 26 out |
| Saturday, July 8 |
| » Lost to Athletics (28-43), 6-5 | Shibe Park (0-3) | 29-46 | Lost 4 |
| » Starters: Walt Masterson vs Bill Beckmann | Fifth | 24½ out |
| » Defeated Athletics (28-44), 6-3 | Shibe Park (1-3) | 30-46 | |
| » Starters: Joe Krakauskas vs Cotton Pippen | Fifth | 24½ out |
| » Major-league debuts: Mickey Vernon (Senators) |
| Sunday, July 9 |
| » Defeated Athletics (28-45), 5-4 | Shibe Park (2-3) | 31-46 | Won 2 |
| » Starters: Dutch Leonard vs Nels Potter | Sixth | 22½ out |
| » Defeated Athletics (28-46), 10-3 | Shibe Park (3-3) | 32-46 | Won 3 |
| » Starters: Ken Chase vs George Caster | Sixth | 22½ out |
| Thursday, July 13 |
| » Lost to Browns (22-53), 4-3 | Sportsman's Park III (3-3) | 32-47 | |
| » Starters: Joe Krakauskas vs Vern Kennedy | Sixth | 22½ out |
| Friday, July 14 |
| » Defeated Browns (22-54), 11-9 | Sportsman's Park III (4-3) | 33-47 | |
| » Starters: Dutch Leonard vs Lefty Mills | Fifth | 22½ out |
| Saturday, July 15 |
| » Lost to Browns (23-54), 8-7 | Sportsman's Park III (4-4) | 33-48 | |
| » Starters: Ken Chase vs Jack Kramer | Sixth | 23½ out |
| Sunday, July 16 |
| » Lost to White Sox (42-35), 3-2 | Comiskey Park I (1-6) | 33-49 | Lost 2 |
| » Starters: Dutch Leonard vs Ted Lyons | Sixth | 25½ out |
| » Lost to White Sox (43-35), 6-3 | Comiskey Park I (1-7) | 33-50 | Lost 3 |
| » Starters: Pete Appleton vs Thornton Lee | Sixth | 25½ out |
| Tuesday, July 18 |
| » Defeated Tigers (40-41), 10-2 | Tiger Stadium (2-4) | 34-50 | |
| » Starters: Joe Krakauskas vs Tommy Bridges | Sixth | 26½ out |
| Wednesday, July 19 |
| » Lost to Tigers (41-41), 11-0 | Tiger Stadium (2-5) | 34-51 | |
| » Starters: Ken Chase vs Schoolboy Rowe | Sixth | 27 out |
| Thursday, July 20 |
| » Defeated Tigers (41-42), 8-7 | Tiger Stadium (3-5) | 35-51 | |
| » Starters: Dutch Leonard vs Al Benton | Sixth | 27 out |
| Friday, July 21 |
| » Lost to Indians (43-39), 5-2 | League Park II (2-4) | 35-52 | |
| » Starters: Joe Haynes vs Al Milnar | Sixth | 27 out |
| Saturday, July 22 |
| » Defeated Indians (43-40), 11-3 | League Park II (3-4) | 36-52 | |
| » Starters: Joe Krakauskas vs Willis Hudlin | Sixth | 26½ out |
| Sunday, July 23 |
| » Lost to Indians (44-40), 11-2 | Cleveland Stadium (0-2) | 36-53 | |
| » Starters: Pete Appleton vs Bob Feller | Sixth | 27½ out |
| » Lost to Indians (45-40), 4-3 | Cleveland Stadium (0-3) | 36-54 | Lost 2 |
| » Starters: Ken Chase vs Johnny Allen | Sixth | 27½ out |
| Tuesday, July 25 |
| » Defeated Tigers (43-45), 5-3 | Griffith Stadium (19-21) | 37-54 | |
| » Starters: Fred Hutchinson vs Dutch Leonard | Sixth | 27½ out |
| Wednesday, July 26 |
| » Lost to Tigers (44-45), 3-1 | Griffith Stadium (19-22) | 37-55 | |
| » Starters: Bobo Newsom vs Joe Krakauskas | Sixth | 28½ out |
| Thursday, July 27 |
| » Lost to Tigers (45-45), 8-1 | Griffith Stadium (19-23) | 37-56 | Lost 2 |
| » Starters: Dizzy Trout vs Walt Masterson | Sixth | 29 out |
| Friday, July 28 |
| » Defeated Indians (47-41), 2-0 | Griffith Stadium (20-23) | 38-56 | |
| » Starters: Bob Feller vs Ken Chase | Sixth | 29 out |
| Saturday, July 29 |
| » Lost to Indians (48-41), 5-2 | Griffith Stadium (20-24) | 38-57 | |
| » Starters: Johnny Allen vs Dutch Leonard | Sixth | 29½ out |
| Sunday, July 30 |
| » Defeated Indians (48-42), 5-2 | Griffith Stadium (21-24) | 39-57 | |
| » Starters: Al Milnar vs Joe Krakauskas | Sixth | 29 out |
| Tuesday, August 1 |
| » Defeated Browns (26-66), 7-5 | Griffith Stadium (22-24) | 40-57 | Won 2 |
| » Starters: Vern Kennedy vs Ken Chase | Sixth | 28 out |
| Wednesday, August 2 |
| » Defeated Browns (26-67), 2-1 | Griffith Stadium (23-24) | 41-57 | Won 3 |
| » Starters: Jack Kramer vs Dutch Leonard | Sixth | 27 out |
| Thursday, August 3 |
| » Defeated Browns (26-68), 9-5 | Griffith Stadium (24-24) | 42-57 | Won 4 |
| » Starters: Lefty Mills vs Joe Krakauskas | Sixth | 27 out |
| Friday, August 4 |
| » Defeated White Sox (55-44), 6-5 | Griffith Stadium (25-24) | 43-57 | Won 5 |
| » Starters: Thornton Lee vs Alex Carrasquel | Sixth | 27 out |
| Future Senator Dennis Higgins is born in Jefferson City, MO. |
| Saturday, August 5 |
| » Defeated White Sox (55-45), 10-1 | Griffith Stadium (26-24) | 44-57 | Won 6 |
| » Starters: Jack Knott vs Ken Chase | Sixth | 27 out |
| Sunday, August 6 |
| » Defeated White Sox (55-46), 4-3 | Griffith Stadium (27-24) | 45-57 | Won 7 |
| » Starters: Ted Lyons vs Dutch Leonard | Sixth | 25½ out |
| Tuesday, August 8 |
| » Defeated Yankees (69-31), 7-4 | Griffith Stadium (28-24) | 46-57 | Won 8 |
| » Starters: Atley Donald vs Joe Krakauskas | Sixth | 24½ out |
| Wednesday, August 9 |
| » Lost to Yankees (70-31), 13-8 | Griffith Stadium (28-25) | 46-58 | |
| » Starters: Red Ruffing vs Ken Chase | Sixth | 25½ out |
| Future Senator Claude Osteen is born in Caney Spring, TN. |
| Thursday, August 10 |
| » Defeated Yankees (70-32), 7-5 | Griffith Stadium (29-25) | 47-58 | |
| » Starters: Monte Pearson vs Dutch Leonard | Sixth | 24½ out |
| Saturday, August 12 |
| » Lost to Red Sox (65-37), 9-5 | Fenway Park (1-6) | 47-59 | |
| » Starters: Joe Krakauskas vs Elden Auker | Sixth | 26 out |
| Sunday, August 13 |
| » Lost to Red Sox (66-37), 9-1 | Fenway Park (1-7) | 47-60 | Lost 2 |
| » Starters: Joe Haynes vs Fritz Ostermueller | Sixth | 26 out |
| » Defeated Red Sox (66-38), 6-3 | Fenway Park (2-7) | 48-60 | |
| » Starters: Alex Carrasquel vs Denny Galehouse | Sixth | 26 out |
| Tuesday, August 15 |
| » Lost to Yankees (74-33), 3-2 | Yankee Stadium (3-3) | 48-61 | |
| » Starters: Ken Chase vs Lefty Gomez | Sixth | 27 out |
| Wednesday, August 16 |
| » Lost to Yankees (75-33), 4-0 | Yankee Stadium (3-4) | 48-62 | Lost 2 |
| » Starters: Dutch Leonard vs Marius Russo | Sixth | 28 out |
| Thursday, August 17 |
| » Lost to Yankees (76-33), 9-8 | Yankee Stadium (3-5) | 48-63 | Lost 3 |
| » Starters: Joe Krakauskas vs Atley Donald | Sixth | 29 out |
| Friday, August 18 |
| » Lost to Red Sox (68-39), 6-2 | Griffith Stadium (29-26) | 48-64 | Lost 4 |
| » Starters: Fritz Ostermueller vs Alex Carrasquel | Sixth | 30 out |
| Saturday, August 19 |
| » Lost to Red Sox (69-39), 8-6 | Griffith Stadium (29-27) | 48-65 | Lost 5 |
| » Starters: Bill LeFebvre vs Joe Haynes | Sixth | 30 out |
| » Defeated Red Sox (69-40), 2-1 | Griffith Stadium (30-27) | 49-65 | |
| » Starters: Jake Wade vs Ken Chase | Sixth | 30 out |
| Sunday, August 20 |
| » Defeated Red Sox (69-41), 2-0 | Griffith Stadium (31-27) | 50-65 | Won 2 |
| » Starters: Jack Wilson vs Dutch Leonard | Sixth | 30 out |
| » Lost to Red Sox (70-41), 10-5 | Griffith Stadium (31-28) | 50-66 | |
| » Starters: Charlie Wagner vs Joe Krakauskas | Sixth | 30 out |
| Tuesday, August 22 |
| » Lost to Indians (59-54), 6-4 | Cleveland Stadium (0-4) | 50-67 | Lost 2 |
| » Starters: Ken Chase vs Bob Feller | Sixth | 31 out |
| Thursday, August 24 |
| » Lost to Tigers (60-56), 8-1 | Tiger Stadium (3-6) | 50-68 | Lost 3 |
| » Starters: Dutch Leonard vs Dizzy Trout | Sixth | 33 out |
| Friday, August 25 |
| » Lost to Tigers (61-56), 5-2 | Tiger Stadium (3-7) | 50-69 | Lost 4 |
| » Starters: Joe Haynes vs Bobo Newsom | Sixth | 34½ out |
| Saturday, August 26 |
| » Lost to Tigers (62-56), 6-3 | Tiger Stadium (3-8) | 50-70 | Lost 5 |
| » Starters: Joe Krakauskas vs Archie McKain | Sixth | 35½ out |
| Sunday, August 27 |
| » Defeated Browns (33-83), 8-7 | Sportsman's Park III (5-4) | 51-70 | |
| » Starters: Dutch Leonard vs Vern Kennedy | Sixth | 35 out |
| » Defeated Browns (33-84), 4-3 | Sportsman's Park III (6-4) | 52-70 | Won 2 |
| » Starters: Ken Chase vs Roxie Lawson | Sixth | 35 out |
| Monday, August 28 |
| » Lost to Browns (34-84), 12-2 | Sportsman's Park III (6-5) | 52-71 | |
| » Starters: Alex Carrasquel vs Bill Trotter | Sixth | 36 out |
| Wednesday, August 30 |
| » Lost to White Sox (68-54), 5-2 | Comiskey Park I (1-8) | 52-72 | Lost 2 |
| » Starters: Joe Haynes vs Ted Lyons | Sixth | 35 out |
| » Defeated White Sox (68-55), 4-3 | Comiskey Park I (2-8) | 53-72 | |
| » Starters: Joe Krakauskas vs Jack Knott | Sixth | 35 out |
| Thursday, August 31 |
| » Defeated White Sox (68-56), 4-3 | Comiskey Park I (3-8) | 54-72 | Won 2 |
| » Starters: Dutch Leonard vs Eddie Smith | Sixth | 34½ out |
| Saturday, September 2 |
| » Lost to Athletics (45-79), 3-0 | Griffith Stadium (31-29) | 54-73 | |
| » Starters: Bill Beckmann vs Ken Chase | Sixth | 35 out |
| Sunday, September 3 |
| » Defeated Athletics (45-80), 6-1 | Griffith Stadium (32-29) | 55-73 | |
| » Starters: Cotton Pippen vs Joe Krakauskas | Sixth | 34 out |
| Monday, September 4 |
| » Defeated Red Sox (76-50), 7-6 | Fenway Park (3-7) | 56-73 | Won 2 |
| » Starters: Joe Haynes vs Jake Wade | Sixth | 34 out |
| » Defeated Red Sox (76-51), 6-4 | Fenway Park (4-7) | 57-73 | Won 3 |
| » Starters: Pete Appleton vs Bill LeFebvre | Sixth | 34 out |
| Wednesday, September 6 |
| » Defeated Athletics (45-83), 6-3 | Shibe Park (4-3) | 58-73 | Won 4 |
| » Starters: Dutch Leonard vs Bill Beckmann | Sixth | 34 out |
| Thursday, September 7 |
| » Defeated Athletics (45-84), 10-1 | Shibe Park (5-3) | 59-73 | Won 5 |
| » Starters: Ken Chase vs Nels Potter | Sixth | 34 out |
| Friday, September 8 |
| » Lost to Athletics (46-84), 5-4 | Shibe Park (5-4) | 59-74 | |
| » Starters: Joe Krakauskas vs Cotton Pippen | Sixth | 35 out |
| Saturday, September 9 |
| » Lost to Yankees (94-38), 5-2 | Yankee Stadium (3-6) | 59-75 | Lost 2 |
| » Starters: Joe Haynes vs Steve Sundra | Sixth | 36 out |
| Sunday, September 10 |
| » Lost to Yankees (95-38), 4-3 | Yankee Stadium (3-7) | 59-76 | Lost 3 |
| » Starters: Pete Appleton vs Marius Russo | Sixth | 38 out |
| » Lost to Yankees (96-38), 6-2 | Yankee Stadium (3-8) | 59-77 | Lost 4 |
| » Starters: Dutch Leonard vs Bump Hadley | Sixth | 38 out |
| Tuesday, September 12 |
| » Lost to White Sox (77-58), 3-2 | Griffith Stadium (32-30) | 59-78 | Lost 5 |
| » Starters: Thornton Lee vs Alex Carrasquel | Sixth | 38 out |
| Wednesday, September 13 |
| » Lost to White Sox (78-58), 3-1 | Griffith Stadium (32-31) | 59-79 | Lost 6 |
| » Starters: Ted Lyons vs Ken Chase | Sixth | 38½ out |
| » Lost to White Sox (79-58), 4-2 | Griffith Stadium (32-32) | 59-80 | Lost 7 |
| » Starters: Jack Knott vs Early Wynn | Sixth | 38½ out |
| » Major-league debuts: Al Evans and Early Wynn (Senators) |
| Thursday, September 14 |
| » Defeated Browns (37-98), 5-1 | Griffith Stadium (33-32) | 60-80 | |
| » Starters: Bill Trotter vs Dutch Leonard | Sixth | 37½ out |
| Friday, September 15 |
| » Lost to Browns (38-98), 9-5 | Griffith Stadium (33-33) | 60-81 | |
| » Starters: Vern Kennedy vs Joe Krakauskas | Sixth | 38½ out |
| Saturday, September 16 |
| » Defeated Browns (38-99), 4-0 | Griffith Stadium (34-33) | 61-81 | |
| » Starters: Roxie Lawson vs Joe Haynes | Sixth | 38½ out |
| Sunday, September 17 |
| » Lost to Tigers (72-67), 3-2 | Griffith Stadium (34-34) | 61-82 | |
| » Starters: Dizzy Trout vs Ken Chase | Sixth | 38 out |
| Monday, September 18 |
| » Defeated Tigers (72-68), 4-2 | Griffith Stadium (35-34) | 62-82 | |
| » Starters: Tommy Bridges vs Dutch Leonard | Sixth | 38 out |
| » Major-league debuts: Elmer Gedeon (Senators) |
| Tuesday, September 19 |
| » Defeated Indians (79-63), 10-9 | Griffith Stadium (36-34) | 63-82 | Won 2 |
| » Starters: Harry Eisenstat vs Early Wynn | Sixth | 38 out |
| Wednesday, September 20 |
| » Lost to Indians (80-63), 7-2 | Griffith Stadium (36-35) | 63-83 | |
| » Starters: Mel Harder vs Joe Krakauskas | Sixth | 39 out |
| Thursday, September 21 |
| » Lost to Indians (81-63), 6-3 | Griffith Stadium (36-36) | 63-84 | Lost 2 |
| » Starters: Al Milnar vs Dick Bass | Sixth | 40 out |
| Saturday, September 23 |
| » Lost to Yankees (103-43), 7-1 | Griffith Stadium (36-37) | 63-85 | Lost 3 |
| » Starters: Monte Pearson vs Dutch Leonard | Sixth | 41 out |
| Sunday, September 24 |
| » Lost to Yankees (104-43), 3-2 | Griffith Stadium (36-38) | 63-86 | Lost 4 |
| » Starters: Lefty Gomez vs Ken Chase | Sixth | 42 out |
| Future Senator Dick Nen is born in South Gate, CA. |
| Monday, September 25 |
| Former Senator Frank LaPorte dies in Newcomerstown, OH at the age of 60. |
| Tuesday, September 26 |
| » Lost to Athletics (54-95), 15-4 | Griffith Stadium (36-39) | 63-87 | Lost 5 |
| » Starters: Bill Beckmann vs Early Wynn | Sixth | 42½ out |
| Thursday, September 28 |
| » Lost to Red Sox (88-60), 4-2 | Griffith Stadium (36-40) | 63-88 | Lost 6 |
| » Starters: Lefty Grove vs Alex Carrasquel | Sixth | 42½ out |
| » Defeated Red Sox (88-61), 6-1 | Griffith Stadium (37-40) | 64-88 | |
| » Starters: Fritz Ostermueller vs Dutch Leonard | Sixth | 42½ out |
| Saturday, September 30 |
| » Defeated Athletics (55-97), 9-5 | Shibe Park (6-4) | 65-88 | Won 2 |
| » Starters: Joe Haynes vs Lynn Nelson | Sixth | 42 out |
| Saturday, October 7 |
| Future Senator Phil Ortega is born in Gilbert, AZ. |
| Sunday, October 15 |
| Future Senator Lou Klimchock is born in Hostetter, PA. |
| Sunday, October 29 |
| Future Senator Pete Richert is born in Floral Park, NY. |
| Tuesday, October 31 |
| Future Senator Ed Stroud is born in Lapine, AL. |
| Sunday, December 3 |
| Future Senator Ron Stillwell is born in Los Angeles, CA. |
| Sunday, December 10 |
| Future Senator Bob Priddy is born in Pittsburgh, PA. |
| Monday, December 18 |
| Future Senator Zoilo Versalles is born in Veldado, Cuba. Future Senator Zoilo Versalles is born in Veldado, Cuba. |
Game information provided by Retrosheet (www.retrosheet.org) |
