| Monday, January 9 |
| Future Athletic Guido Grilli is born in Memphis, TN. |
| Saturday, February 18 |
| Future Athletic Jesse Hickman is born in Lecompte, LA. |
| Tuesday, April 18 |
| » Major-league debuts: Frank Croucher and Barney McCosky (Tigers) Ken Silvestri (White Sox) |
| Wednesday, April 19 |
| » Major-league debuts: Ralph Hodgin (Braves) |
| Thursday, April 20 |
| » Defeated Senators (0-1), 2-0 | Shibe Park (1-0) | 1-0 | |
| » Starters: Jimmie DeShong vs George Caster | Second | ½ out |
| Friday, April 21 |
| » Lost to Red Sox (1-1), 9-2 | Fenway Park (0-1) | 1-1 | |
| » Starters: Roy Parmelee vs Jim Bagby | Fifth | 1 out |
| Saturday, April 22 |
| » Lost to Red Sox (2-1), 5-2 | Fenway Park (0-2) | 1-2 | Lost 2 |
| » Starters: Buck Ross vs Woody Rich | Fifth | 1½ out |
| Sunday, April 23 |
| » Defeated Red Sox (2-2), 12-8 | Fenway Park (1-2) | 2-2 | |
| » Starters: Bud Thomas vs Elden Auker | Fifth | 1 out |
| Monday, April 24 |
| » Lost to Yankees (4-1), 2-1 | Yankee Stadium (0-1) | 2-3 | |
| » Starters: Nels Potter vs Monte Pearson | Fourth | 2 out |
| Tuesday, April 25 |
| » Lost to Yankees (5-1), 8-4 | Yankee Stadium (0-2) | 2-4 | Lost 2 |
| » Starters: Bud Thomas vs Red Ruffing | Sixth | 3 out |
| Wednesday, April 26 |
| » Major-league debuts: Joe Dobson (Indians) |
| Thursday, April 27 |
| » Lost to Senators (3-4), 6-3 | Griffith Stadium (0-1) | 2-5 | Lost 3 |
| » Starters: George Caster vs Dutch Leonard | Sixth | 3½ out |
| Saturday, April 29 |
| » Lost to Red Sox (4-3), 3-2 | Shibe Park (1-1) | 2-6 | Lost 4 |
| » Starters: Lefty Grove vs Buck Ross | Seventh | 3½ out |
| Sunday, April 30 |
| » Lost to Red Sox (5-3), 3-1 | Shibe Park (1-2) | 2-7 | Lost 5 |
| » Starters: Jim Bagby vs George Caster | Seventh | 3½ out |
| Monday, May 1 |
| » Major-league debuts: Dave Coble (Phillies) |
| Tuesday, May 2 |
| » Lost to White Sox (7-4), 4-1 | Comiskey Park I (0-1) | 2-8 | Lost 6 |
| » Starters: Roy Parmelee vs Ted Lyons | Seventh | 4½ out |
| Wednesday, May 3 |
| » Defeated White Sox (7-5), 3-1 | Comiskey Park I (1-1) | 3-8 | |
| » Starters: George Caster vs Bill Dietrich | Seventh | 4½ out |
| Thursday, May 4 |
| » Lost to Browns (5-7), 9-3 | Sportsman's Park III (0-1) | 3-9 | |
| » Starters: Buck Ross vs Jack Kramer | Eighth | 5½ out |
| Friday, May 5 |
| » Defeated Browns (5-8), 10-5 | Sportsman's Park III (1-1) | 4-9 | |
| » Starters: Nels Potter vs Bill Trotter | Seventh | 5 out |
| Saturday, May 6 |
| » Lost to Browns (6-8), 7-5 | Sportsman's Park III (1-2) | 4-10 | |
| » Starters: Roy Parmelee vs Johnny Marcum | Eighth | 6 out |
| Sunday, May 7 |
| » Defeated Tigers (6-11), 10-3 | Tiger Stadium (1-0) | 5-10 | |
| » Starters: George Caster vs Al Benton | Seventh | 5½ out |
| Monday, May 8 |
| » Defeated Tigers (6-12), 6-5 | Tiger Stadium (2-0) | 6-10 | Won 2 |
| » Starters: Buck Ross vs Bob Harris | Sixth | 4½ out |
| Wednesday, May 10 |
| » Lost to Indians (8-9), 7-4 | League Park II (0-1) | 6-11 | |
| » Starters: Nels Potter vs Bob Feller | Seventh | 5½ out |
| Thursday, May 11 |
| » Lost to Indians (9-9), 7-0 | League Park II (0-2) | 6-12 | Lost 2 |
| » Starters: Bob Joyce vs Al Milnar | Eighth | 7 out |
| Future Athletic Hector Martinez is born in Las Villas, Cuba. |
| Sunday, May 14 |
| » Lost to Yankees (14-5), 10-0 | Shibe Park (1-3) | 6-13 | Lost 3 |
| » Starters: Red Ruffing vs George Caster | Eighth | 8 out |
| Monday, May 15 |
| » Lost to Yankees (15-5), 3-0 | Shibe Park (1-4) | 6-14 | Lost 4 |
| » Starters: Wes Ferrell vs Buck Ross | Eighth | 9 out |
| Tuesday, May 16 |
| » Lost to Indians (12-10), 8-3 | Shibe Park (1-5) | 6-15 | Lost 5 |
| » Starters: Al Milnar vs Lynn Nelson | Eighth | 10 out |
| Thursday, May 18 |
| » Defeated Indians (12-11), 4-3 | Shibe Park (2-5) | 7-15 | |
| » Starters: Johnny Allen vs George Caster | Eighth | 10½ out |
| Friday, May 19 |
| » Defeated Tigers (10-18), 11-6 | Shibe Park (3-5) | 8-15 | Won 2 |
| » Starters: Al Benton vs Buck Ross | Seventh | 10½ out |
| Saturday, May 20 |
| » Defeated Tigers (10-19), 6-5 | Shibe Park (4-5) | 9-15 | Won 3 |
| » Starters: Schoolboy Rowe vs Nels Potter | Sixth | 10½ out |
| Sunday, May 21 |
| » Defeated Browns (10-18), 12-4 | Shibe Park (5-5) | 10-15 | Won 4 |
| » Starters: Roxie Lawson vs Roy Parmelee | Sixth | 10½ out |
| Monday, May 22 |
| » Lost to Browns (11-18), 6-3 | Shibe Park (5-6) | 10-16 | |
| » Starters: Vern Kennedy vs George Caster | Sixth | 11 out |
| Tuesday, May 23 |
| » Defeated Browns (11-19), 7-3 | Shibe Park (6-6) | 11-16 | |
| » Starters: George Gill vs Lynn Nelson | Fifth | 11 out |
| Wednesday, May 24 |
| » Lost to White Sox (17-13), 4-1 | Shibe Park (6-7) | 11-17 | |
| » Starters: Eddie Smith vs Buck Ross | Sixth | 11 out |
| Future Athletic Jim Duckworth is born in National City, CA. |
| Friday, May 26 |
| » Lost to Yankees (24-6), 1-0 | Yankee Stadium (0-3) | 11-18 | Lost 2 |
| » Starters: Cotton Pippen vs Oral Hildebrand | Sixth | 12½ out |
| Saturday, May 27 |
| » Lost to Yankees (25-6), 8-2 | Yankee Stadium (0-4) | 11-19 | Lost 3 |
| » Starters: Roy Parmelee vs Lefty Gomez | Seventh | 14½ out |
| » Lost to Yankees (26-6), 11-9 | Yankee Stadium (0-5) | 11-20 | Lost 4 |
| » Starters: Bob Joyce vs Monte Pearson | Seventh | 14½ out |
| Sunday, May 28 |
| » Lost to Yankees (27-6), 9-5 | Yankee Stadium (0-6) | 11-21 | Lost 5 |
| » Starters: Lynn Nelson vs Atley Donald | Seventh | 15½ out |
| Monday, May 29 |
| » Defeated Senators (13-21), 5-4 | Griffith Stadium (1-1) | 12-21 | |
| » Starters: Buck Ross vs Joe Krakauskas | Seventh | 15½ out |
| Tuesday, May 30 |
| » Defeated Senators (13-22), 3-1 | Griffith Stadium (2-1) | 13-21 | Won 2 |
| » Starters: Nels Potter vs Alex Carrasquel | Seventh | 15½ out |
| » Lost to Senators (14-22), 8-4 | Griffith Stadium (2-2) | 13-22 | |
| » Starters: Cotton Pippen vs Ken Chase | Seventh | 15½ out |
| Thursday, June 1 |
| » Defeated Browns (11-27), 10-7 | Sportsman's Park III (2-2) | 14-22 | |
| » Starters: Lynn Nelson vs Jack Kramer | Seventh | 15½ out |
| Saturday, June 3 |
| » Defeated Browns (11-28), 5-3 | Sportsman's Park III (3-2) | 15-22 | Won 2 |
| » Starters: Bill Beckmann vs George Gill | Sixth | 15½ out |
| » Defeated Browns (11-29), 8-6 | Sportsman's Park III (4-2) | 16-22 | Won 3 |
| » Starters: Buck Ross vs Roxie Lawson | Sixth | 15½ out |
| Sunday, June 4 |
| » Lost to White Sox (22-17), 14-9 | Comiskey Park I (1-2) | 16-23 | |
| » Starters: Cotton Pippen vs Ted Lyons | Fifth | 16 out |
| » Defeated White Sox (22-18), 11-6 | Comiskey Park I (2-2) | 17-23 | |
| » Starters: Nels Potter vs Bill Dietrich | Fifth | 16 out |
| Monday, June 5 |
| » Lost to White Sox (23-18), 12-1 | Comiskey Park I (2-3) | 17-24 | |
| » Starters: Bob Joyce vs Jack Knott | Sixth | 16 out |
| Tuesday, June 6 |
| » Lost to White Sox (24-18), 7-4 | Comiskey Park I (2-4) | 17-25 | Lost 2 |
| » Starters: George Caster vs Bill Dietrich | Sixth | 16 out |
| Wednesday, June 7 |
| » Defeated Tigers (19-25), 5-4 | Tiger Stadium (3-0) | 18-25 | |
| » Starters: Lynn Nelson vs Schoolboy Rowe | Sixth | 16 out |
| Thursday, June 8 |
| » Lost to Tigers (20-25), 8-4 | Tiger Stadium (3-1) | 18-26 | |
| » Starters: Bill Beckmann vs Dizzy Trout | Sixth | 17 out |
| Friday, June 9 |
| » Lost to Tigers (21-25), 14-4 | Tiger Stadium (3-2) | 18-27 | Lost 2 |
| » Starters: Buck Ross vs Al Benton | Sixth | 17½ out |
| Saturday, June 10 |
| » Lost to Indians (25-21), 6-0 | League Park II (0-3) | 18-28 | Lost 3 |
| » Starters: Nels Potter vs Johnny Allen | Sixth | 18 out |
| Sunday, June 11 |
| » Lost to Indians (26-21), 4-3 | League Park II (0-4) | 18-29 | Lost 4 |
| » Starters: Cotton Pippen vs Willis Hudlin | Sixth | 20 out |
| » Lost to Indians (27-21), 3-2 | League Park II (0-5) | 18-30 | Lost 5 |
| » Starters: George Caster vs Al Milnar | Sixth | 20 out |
| Wednesday, June 14 |
| » Lost to Browns (14-35), 6-0 | Shibe Park (6-8) | 18-31 | Lost 6 |
| » Starters: Vern Kennedy vs Lynn Nelson | Seventh | 20 out |
| Friday, June 16 |
| » Defeated Browns (14-36), 11-10 | Shibe Park (7-8) | 19-31 | |
| » Starters: John Whitehead vs Buck Ross | Sixth | 20½ out |
| Saturday, June 17 |
| » Defeated White Sox (27-24), 5-2 | Shibe Park (8-8) | 20-31 | Won 2 |
| » Starters: Bill Dietrich vs George Caster | Sixth | 20½ out |
| Sunday, June 18 |
| » Lost to White Sox (28-24), 6-5 | Shibe Park (8-9) | 20-32 | |
| » Starters: Ted Lyons vs Cotton Pippen | Fifth | 20 out |
| » Defeated White Sox (28-25), 9-4 | Shibe Park (9-9) | 21-32 | |
| » Starters: Johnny Rigney vs Nels Potter | Fifth | 20 out |
| Tuesday, June 20 |
| » Lost to Tigers (30-27), 5-0 | Shibe Park (9-10) | 21-33 | |
| » Starters: Tommy Bridges vs George Caster | Sixth | 21½ out |
| Thursday, June 22 |
| » Defeated Tigers (30-28), 6-5 | Shibe Park (10-10) | 22-33 | |
| » Starters: Bobo Newsom vs Lynn Nelson | Sixth | 22 out |
| Friday, June 23 |
| » Lost to Indians (31-26), 12-5 | Shibe Park (10-11) | 22-34 | |
| » Starters: Bob Feller vs Bill Beckmann | Sixth | 22½ out |
| Saturday, June 24 |
| » Defeated Indians (31-27), 10-6 | Shibe Park (11-11) | 23-34 | |
| » Starters: Willis Hudlin vs Nels Potter | Sixth | 22½ out |
| Sunday, June 25 |
| » Lost to Indians (32-27), 8-4 | Shibe Park (11-12) | 23-35 | |
| » Starters: Johnny Allen vs Buck Ross | Sixth | 22½ out |
| » Defeated Indians (32-28), 10-2 | Shibe Park (12-12) | 24-35 | |
| » Starters: Al Milnar vs George Caster | Sixth | 22½ out |
| Monday, June 26 |
| » Defeated Yankees (46-13), 3-2 | Shibe Park (13-12) | 25-35 | Won 2 |
| » Starters: Bump Hadley vs Cotton Pippen | Sixth | 21½ out |
| Wednesday, June 28 |
| » Lost to Yankees (47-13), 23-2 | Shibe Park (13-13) | 25-36 | |
| » Starters: Monte Pearson vs Lynn Nelson | Sixth | 23½ out |
| » Lost to Yankees (48-13), 10-0 | Shibe Park (13-14) | 25-37 | Lost 2 |
| » Starters: Lefty Gomez vs George Caster | Sixth | 23½ out |
| Thursday, June 29 |
| » Defeated Red Sox (33-24), 8-6 | Fenway Park (2-2) | 26-37 | |
| » Manager: Earle Mack |
| » Starters: Nels Potter vs Jack Wilson | Sixth | 23 out |
| Saturday, July 1 |
| » Lost to Senators (26-42), 9-4 | Griffith Stadium (2-3) | 26-38 | |
| » Starters: Buck Ross vs Joe Haynes | Sixth | 23½ out |
| Sunday, July 2 |
| » Lost to Senators (27-42), 4-3 | Griffith Stadium (2-4) | 26-39 | Lost 2 |
| » Starters: Bill Beckmann vs Walt Masterson | Seventh | 24½ out |
| » Lost to Senators (28-42), 13-2 | Griffith Stadium (2-5) | 26-40 | Lost 3 |
| » Starters: Chubby Dean vs Joe Krakauskas | Seventh | 24½ out |
| Tuesday, July 4 |
| » Lost to Red Sox (36-25), 17-7 | Shibe Park (13-15) | 26-41 | Lost 4 |
| » Starters: Emerson Dickman vs Cotton Pippen | Seventh | 25½ out |
| » Lost to Red Sox (37-25), 18-12 | Shibe Park (13-16) | 26-42 | Lost 5 |
| » Starters: Woody Rich vs George Caster | Seventh | 25½ out |
| » Major-league debuts: Eddie Collins (Athletics) |
| Wednesday, July 5 |
| » Lost to Red Sox (38-25), 6-4 | Shibe Park (13-17) | 26-43 | Lost 6 |
| » Starters: Elden Auker vs Nels Potter | Sixth | 26½ out |
| Thursday, July 6 |
| » Defeated Senators (29-45), 9-3 | Shibe Park (14-17) | 27-43 | |
| » Starters: Joe Haynes vs George Caster | Seventh | 26 out |
| Saturday, July 8 |
| » Defeated Senators (29-46), 6-5 | Shibe Park (15-17) | 28-43 | Won 2 |
| » Starters: Walt Masterson vs Bill Beckmann | Sixth | 24½ out |
| » Lost to Senators (30-46), 6-3 | Shibe Park (15-18) | 28-44 | |
| » Starters: Joe Krakauskas vs Cotton Pippen | Sixth | 24½ out |
| » Major-league debuts: Mickey Vernon (Senators) |
| Sunday, July 9 |
| » Lost to Senators (31-46), 5-4 | Shibe Park (15-19) | 28-45 | Lost 2 |
| » Starters: Dutch Leonard vs Nels Potter | Seventh | 24½ out |
| » Lost to Senators (32-46), 10-3 | Shibe Park (15-20) | 28-46 | Lost 3 |
| » Starters: Ken Chase vs George Caster | Seventh | 24½ out |
| Thursday, July 13 |
| » Defeated White Sox (40-34), 12-10 | Comiskey Park I (3-4) | 29-46 | |
| » Starters: Nels Potter vs Eddie Smith | Seventh | 23½ out |
| Friday, July 14 |
| » Defeated White Sox (40-35), 7-3 | Comiskey Park I (4-4) | 30-46 | Won 2 |
| » Starters: Buck Ross vs Jack Knott | Sixth | 23½ out |
| Saturday, July 15 |
| » Lost to White Sox (41-35), 7-3 | Comiskey Park I (4-5) | 30-47 | |
| » Starters: Nels Potter vs Johnny Rigney | Seventh | 24½ out |
| Sunday, July 16 |
| » Lost to Browns (24-54), 13-7 | Sportsman's Park III (4-3) | 30-48 | Lost 2 |
| » Starters: Bill Beckmann vs George Gill | Seventh | 26 out |
| » Tied Browns, 5-5 | Sportsman's Park III (4-3) | 30-48 | |
| » Starters: Cotton Pippen vs Bob Harris | Seventh | 26 out |
| Monday, July 17 |
| » Defeated Browns (24-55), 11-8 | Sportsman's Park III (5-3) | 31-48 | |
| » Starters: Lynn Nelson vs Vern Kennedy | Seventh | 26 out |
| Tuesday, July 18 |
| » Lost to Indians (41-39), 6-3 | Cleveland Stadium (0-1) | 31-49 | |
| » Starters: Buck Ross vs Johnny Allen | Seventh | 27½ out |
| Thursday, July 20 |
| » Lost to Indians (42-39), 3-2 | League Park II (0-6) | 31-50 | Lost 2 |
| » Starters: Bill Beckmann vs Mel Harder | Seventh | 28½ out |
| Friday, July 21 |
| » Defeated Tigers (41-43), 6-2 | Tiger Stadium (4-2) | 32-50 | |
| » Starters: Cotton Pippen vs Dizzy Trout | Seventh | 27½ out |
| Saturday, July 22 |
| » Defeated Tigers (41-44), 4-2 | Tiger Stadium (5-2) | 33-50 | Won 2 |
| » Starters: Lynn Nelson vs Bobo Newsom | Seventh | 27½ out |
| » Lost to Tigers (42-44), 11-10 | Tiger Stadium (5-3) | 33-51 | |
| » Starters: Nels Potter vs Schoolboy Rowe | Seventh | 27½ out |
| Sunday, July 23 |
| » Lost to Tigers (43-44), 16-3 | Tiger Stadium (5-4) | 33-52 | Lost 2 |
| » Starters: Buck Ross vs Tommy Bridges | Seventh | 28 out |
| » Major-league debuts: Harry O'Neill (Athletics) |
| Tuesday, July 25 |
| » Lost to Indians (46-40), 12-8 | Shibe Park (15-21) | 33-53 | Lost 3 |
| » Starters: Mel Harder vs Bill Beckmann | Seventh | 29 out |
| Wednesday, July 26 |
| » Lost to Indians (47-40), 9-3 | Shibe Park (15-22) | 33-54 | Lost 4 |
| » Starters: Al Milnar vs Nels Potter | Seventh | 30 out |
| Friday, July 28 |
| » Defeated Tigers (45-46), 3-0 | Shibe Park (16-22) | 34-54 | |
| » Starters: Schoolboy Rowe vs Buck Ross | Seventh | 30 out |
| Saturday, July 29 |
| » Lost to Tigers (46-46), 7-6 | Shibe Park (16-23) | 34-55 | |
| » Starters: Tommy Bridges vs Lynn Nelson | Seventh | 30½ out |
| Sunday, July 30 |
| » Lost to Tigers (47-46), 14-0 | Shibe Park (16-24) | 34-56 | Lost 2 |
| » Starters: Bobo Newsom vs Bill Beckmann | Seventh | 31½ out |
| » Lost to Tigers (48-46), 5-3 | Shibe Park (16-25) | 34-57 | Lost 3 |
| » Starters: Fred Hutchinson vs Cotton Pippen | Seventh | 31½ out |
| Tuesday, August 1 |
| » Lost to White Sox (53-42), 4-1 | Shibe Park (16-26) | 34-58 | Lost 4 |
| » Starters: Jack Knott vs Nels Potter | Seventh | 31½ out |
| Wednesday, August 2 |
| » Defeated White Sox (53-43), 13-4 | Shibe Park (17-26) | 35-58 | |
| » Starters: Bill Dietrich vs Buck Ross | Seventh | 31 out |
| » Lost to White Sox (54-43), 2-1 | Shibe Park (17-27) | 35-59 | |
| » Starters: Johnny Rigney vs Lynn Nelson | Seventh | 31 out |
| Thursday, August 3 |
| » Lost to White Sox (55-43), 9-7 | Shibe Park (17-28) | 35-60 | Lost 2 |
| » Starters: Eddie Smith vs Bill Beckmann | Seventh | 32 out |
| Friday, August 4 |
| » Lost to Browns (27-68), 3-1 | Shibe Park (17-29) | 35-61 | Lost 3 |
| » Starters: Bill Trotter vs Bob Joyce | Seventh | 33 out |
| Saturday, August 5 |
| » Defeated Browns (27-69), 10-7 | Shibe Park (18-29) | 36-61 | |
| » Starters: Bob Harris vs Nels Potter | Seventh | 33 out |
| Sunday, August 6 |
| » Lost to Browns (28-69), 11-4 | Shibe Park (18-30) | 36-62 | |
| » Starters: Vern Kennedy vs Buck Ross | Seventh | 33 out |
| » Lost to Browns (29-69), 8-6 | Shibe Park (18-31) | 36-63 | Lost 2 |
| » Starters: John Whitehead vs Lynn Nelson | Seventh | 33 out |
| Tuesday, August 8 |
| » Lost to Red Sox (61-37), 9-2 | Fenway Park (2-3) | 36-64 | Lost 3 |
| » Starters: Bob Joyce vs Lefty Grove | Seventh | 33 out |
| Wednesday, August 9 |
| » Lost to Red Sox (62-37), 5-3 | Fenway Park (2-4) | 36-65 | Lost 4 |
| » Starters: Buck Ross vs Woody Rich | Seventh | 34½ out |
| » Lost to Red Sox (63-37), 6-5 | Fenway Park (2-5) | 36-66 | Lost 5 |
| » Starters: Bill Beckmann vs Joe Heving | Seventh | 34½ out |
| Thursday, August 10 |
| » Lost to Red Sox (64-37), 7-5 | Fenway Park (2-6) | 36-67 | Lost 6 |
| » Starters: Lynn Nelson vs Jack Wilson | Seventh | 34½ out |
| Friday, August 11 |
| » Lost to Yankees (71-32), 9-5 | Shibe Park (18-32) | 36-68 | Lost 7 |
| » Starters: Lefty Gomez vs Nels Potter | Seventh | 35½ out |
| Saturday, August 12 |
| » Lost to Yankees (72-32), 18-4 | Shibe Park (18-33) | 36-69 | Lost 8 |
| » Starters: Oral Hildebrand vs Bob Joyce | Seventh | 36½ out |
| Sunday, August 13 |
| » Defeated Yankees (72-33), 12-9 | Shibe Park (19-33) | 37-69 | |
| » Starters: Atley Donald vs Buck Ross | Seventh | 36½ out |
| » Lost to Yankees (73-33), 21-0 | Shibe Park (19-34) | 37-70 | |
| » Starters: Red Ruffing vs Cotton Pippen | Seventh | 36½ out |
| Future Athletic Bill Stafford is born in Catskill, NY. |
| Tuesday, August 15 |
| » Defeated Red Sox (66-39), 3-0 | Shibe Park (20-34) | 38-70 | |
| » Starters: Jack Wilson vs Lynn Nelson | Seventh | 36½ out |
| Thursday, August 17 |
| » Lost to Red Sox (67-39), 7-1 | Shibe Park (20-35) | 38-71 | |
| » Starters: Lefty Grove vs Jim Reninger | Seventh | 38 out |
| Friday, August 18 |
| » Lost to Yankees (77-33), 5-0 | Yankee Stadium (0-7) | 38-72 | Lost 2 |
| » Starters: Cotton Pippen vs Red Ruffing | Seventh | 39 out |
| Sunday, August 20 |
| » Defeated Yankees (77-34), 5-4 | Yankee Stadium (1-7) | 39-72 | |
| » Starters: Buck Ross vs Lefty Gomez | Seventh | 39 out |
| » Lost to Yankees (78-34), 5-1 | Yankee Stadium (1-8) | 39-73 | |
| » Starters: Lynn Nelson vs Steve Sundra | Seventh | 39 out |
| Tuesday, August 22 |
| » Lost to Tigers (59-55), 9-4 | Tiger Stadium (5-5) | 39-74 | Lost 2 |
| » Starters: Bill Beckmann vs Tommy Bridges | Seventh | 40 out |
| Wednesday, August 23 |
| » Defeated Tigers (59-56), 7-6 | Tiger Stadium (6-5) | 40-74 | |
| » Starters: Cotton Pippen vs Fred Hutchinson | Seventh | 40½ out |
| Thursday, August 24 |
| » Lost to Indians (60-54), 10-2 | League Park II (0-7) | 40-75 | |
| » Starters: Buck Ross vs Mel Harder | Seventh | 42 out |
| » Lost to Indians (61-54), 17-2 | League Park II (0-8) | 40-76 | Lost 2 |
| » Starters: Jim Reninger vs Al Milnar | Seventh | 42 out |
| Friday, August 25 |
| » Lost to Indians (62-54), 6-0 | League Park II (0-9) | 40-77 | Lost 3 |
| » Starters: Lynn Nelson vs Harry Eisenstat | Seventh | 43½ out |
| Saturday, August 26 |
| » Lost to Indians (63-54), 7-5 | League Park II (0-10) | 40-78 | Lost 4 |
| » Starters: Nels Potter vs Johnny Allen | Seventh | 44½ out |
| Sunday, August 27 |
| » Defeated White Sox (66-54), 2-0 | Comiskey Park I (5-5) | 41-78 | |
| » Starters: Bill Beckmann vs Thornton Lee | Seventh | 44½ out |
| Monday, August 28 |
| » Lost to White Sox (67-54), 5-4 | Comiskey Park I (5-6) | 41-79 | |
| » Starters: Buck Ross vs Johnny Rigney | Seventh | 45½ out |
| Wednesday, August 30 |
| » Defeated Browns (34-85), 9-8 | Sportsman's Park III (6-3) | 42-79 | |
| » Starters: Cotton Pippen vs Jack Kramer | Seventh | 43½ out |
| » Defeated Browns (34-86), 2-0 | Sportsman's Park III (7-3) | 43-79 | Won 2 |
| » Starters: Lynn Nelson vs Bob Harris | Seventh | 43½ out |
| Thursday, August 31 |
| » Defeated Browns (34-87), 4-2 | Sportsman's Park III (8-3) | 44-79 | Won 3 |
| » Starters: Nels Potter vs Vern Kennedy | Seventh | 43 out |
| Saturday, September 2 |
| » Defeated Senators (54-73), 3-0 | Griffith Stadium (3-5) | 45-79 | Won 4 |
| » Starters: Bill Beckmann vs Ken Chase | Seventh | 42½ out |
| Sunday, September 3 |
| » Lost to Senators (55-73), 6-1 | Griffith Stadium (3-6) | 45-80 | |
| » Starters: Cotton Pippen vs Joe Krakauskas | Seventh | 42½ out |
| Monday, September 4 |
| » Lost to Yankees (89-38), 7-6 | Shibe Park (20-36) | 45-81 | Lost 2 |
| » Starters: Atley Donald vs Buck Ross | Seventh | 44½ out |
| » Lost to Yankees (90-38), 2-0 | Shibe Park (20-37) | 45-82 | Lost 3 |
| » Starters: Marius Russo vs Lynn Nelson | Seventh | 44½ out |
| Wednesday, September 6 |
| » Lost to Senators (58-73), 6-3 | Shibe Park (20-38) | 45-83 | Lost 4 |
| » Starters: Dutch Leonard vs Bill Beckmann | Seventh | 45½ out |
| Thursday, September 7 |
| » Lost to Senators (59-73), 10-1 | Shibe Park (20-39) | 45-84 | Lost 5 |
| » Starters: Ken Chase vs Nels Potter | Seventh | 46½ out |
| Friday, September 8 |
| » Defeated Senators (59-74), 5-4 | Shibe Park (21-39) | 46-84 | |
| » Starters: Joe Krakauskas vs Cotton Pippen | Seventh | 46½ out |
| Saturday, September 9 |
| » Defeated Red Sox (76-55), 2-1 | Shibe Park (22-39) | 47-84 | Won 2 |
| » Starters: Elden Auker vs Buck Ross | Seventh | 46½ out |
| Sunday, September 10 |
| » Lost to Red Sox (77-55), 10-7 | Shibe Park (22-40) | 47-85 | |
| » Starters: Charlie Wagner vs Bill Beckmann | Seventh | 48½ out |
| » Lost to Red Sox (78-55), 5-1 | Shibe Park (22-41) | 47-86 | Lost 2 |
| » Starters: Joe Heving vs Lynn Nelson | Seventh | 48½ out |
| Monday, September 11 |
| » Lost to Red Sox (79-55), 11-9 | Shibe Park (22-42) | 47-87 | Lost 3 |
| » Starters: Fritz Ostermueller vs Nels Potter | Seventh | 49 out |
| Tuesday, September 12 |
| » Defeated Browns (36-97), 9-1 | Shibe Park (23-42) | 48-87 | |
| » Starters: Vern Kennedy vs Les McCrabb | Seventh | 48 out |
| Wednesday, September 13 |
| » Lost to Browns (37-97), 11-3 | Shibe Park (23-43) | 48-88 | |
| » Starters: Jack Kramer vs Buck Ross | Seventh | 48 out |
| Thursday, September 14 |
| » Defeated White Sox (79-59), 4-2 | Shibe Park (24-43) | 49-88 | |
| » Starters: Eddie Smith vs Nels Potter | Seventh | 47 out |
| » Major-league debuts: Bob Kennedy (White Sox) |
| Friday, September 15 |
| » Defeated White Sox (79-60), 3-2 | Shibe Park (25-43) | 50-88 | Won 2 |
| » Starters: Bill Dietrich vs Lynn Nelson | Seventh | 47 out |
| Saturday, September 16 |
| » Defeated White Sox (79-61), 7-6 | Shibe Park (26-43) | 51-88 | Won 3 |
| » Starters: Johnny Rigney vs Bill Beckmann | Seventh | 47 out |
| Sunday, September 17 |
| » Defeated Indians (77-62), 4-2 | Shibe Park (27-43) | 52-88 | Won 4 |
| » Starters: Bob Feller vs Les McCrabb | Seventh | 46 out |
| » Lost to Indians (78-62), 18-5 | Shibe Park (27-44) | 52-89 | |
| » Starters: Al Milnar vs Buck Ross | Seventh | 46 out |
| Monday, September 18 |
| » Lost to Indians (79-62), 9-4 | Shibe Park (27-45) | 52-90 | Lost 2 |
| » Starters: Johnny Allen vs Sam Page | Seventh | 47 out |
| Tuesday, September 19 |
| » Lost to Tigers (73-68), 8-4 | Shibe Park (27-46) | 52-91 | Lost 3 |
| » Starters: Bobo Newsom vs Nels Potter | Seventh | 48 out |
| Wednesday, September 20 |
| » Defeated Tigers (73-69), 5-4 | Shibe Park (28-46) | 53-91 | |
| » Starters: Fred Hutchinson vs Lynn Nelson | Seventh | 48 out |
| Thursday, September 21 |
| » Lost to Tigers (74-69), 7-6 | Shibe Park (28-47) | 53-92 | |
| » Starters: Cotton Pippen vs Bill Beckmann | Seventh | 49 out |
| Friday, September 22 |
| » Lost to Red Sox (85-60), 7-5 | Fenway Park (2-7) | 53-93 | Lost 2 |
| » Starters: Les McCrabb vs Charlie Wagner | Seventh | 49½ out |
| Saturday, September 23 |
| » Lost to Red Sox (86-60), 10-8 | Fenway Park (2-8) | 53-94 | Lost 3 |
| » Starters: Sam Page vs Jack Wilson | Seventh | 50½ out |
| Sunday, September 24 |
| » Lost to Red Sox (87-60), 9-4 | Fenway Park (2-9) | 53-95 | Lost 4 |
| » Starters: Lynn Nelson vs Joe Heving | Seventh | 51½ out |
| Tuesday, September 26 |
| » Defeated Senators (63-87), 15-4 | Griffith Stadium (4-6) | 54-95 | |
| » Starters: Bill Beckmann vs Early Wynn | Seventh | 51 out |
| Thursday, September 28 |
| » Lost to Yankees (105-43), 8-4 | Yankee Stadium (1-9) | 54-96 | |
| » Starters: Les McCrabb vs Oral Hildebrand | Seventh | 51 out |
| » Defeated Yankees (105-44), 5-4 | Yankee Stadium (2-9) | 55-96 | |
| » Starters: Sam Page vs Bump Hadley | Seventh | 51 out |
| Saturday, September 30 |
| » Lost to Senators (65-88), 9-5 | Shibe Park (28-48) | 55-97 | |
| » Starters: Joe Haynes vs Lynn Nelson | Seventh | 51½ out |
| Monday, October 23 |
| Future Athletic George Williams is born in Detroit, MI. |
| Thursday, October 26 |
| Former Athletic Ed Lennox dies in Camden, NJ at the age of 54. |
Game information provided by Retrosheet (www.retrosheet.org) |
