| Sunday, March 20 |
| Former Tiger Bob Fothergill dies in Detroit, MI at the age of 41. |
| Monday, April 18 |
| » Major-league debuts: Taffy Wright (Senators) |
| Tuesday, April 19 |
| » Lost to White Sox (1-0), 4-3 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Roxie Lawson vs John Whitehead | Fifth | 1½ out |
| » Major-league debuts: Roy Cullenbine and Don Ross (Tigers) |
| Wednesday, April 20 |
| » Lost to White Sox (2-0), 5-4 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » Starters: Vern Kennedy vs Sugar Cain | Sixth | 2½ out |
| » Major-league debuts: Mark Christman (Tigers) |
| Thursday, April 21 |
| » Defeated White Sox (2-1), 9-3 | Comiskey Park I (1-2) | 1-2 | |
| » Starters: Elden Auker vs Bill Dietrich | Fourth | 2 out |
| Friday, April 22 |
| » Lost to Indians (3-1), 4-3 | Tiger Stadium (0-1) | 1-3 | |
| » Starters: Mel Harder vs Tommy Bridges | Third | 2 out |
| Saturday, April 23 |
| » Lost to Indians (4-1), 6-3 | Tiger Stadium (0-2) | 1-4 | Lost 2 |
| » Starters: Johnny Allen vs Jake Wade | Fifth | 3 out |
| Sunday, April 24 |
| » Lost to Indians (5-1), 9-4 | Tiger Stadium (0-3) | 1-5 | Lost 3 |
| » Starters: Bob Feller vs George Gill | Sixth | 4 out |
| Monday, April 25 |
| » Defeated Browns (3-4), 10-1 | Sportsman's Park III (1-0) | 2-5 | |
| » Starters: Vern Kennedy vs Ed Cole | Eighth | 3½ out |
| Tuesday, April 26 |
| » Defeated Browns (3-5), 7-1 | Sportsman's Park III (2-0) | 3-5 | Won 2 |
| » Starters: Elden Auker vs Oral Hildebrand | Fifth | 3½ out |
| Wednesday, April 27 |
| » Lost to Browns (4-5), 7-2 | Sportsman's Park III (2-1) | 3-6 | |
| » Starters: Tommy Bridges vs Bobo Newsom | Seventh | 3½ out |
| Friday, April 29 |
| » Defeated White Sox (4-5), 5-1 | Tiger Stadium (1-3) | 4-6 | |
| » Starters: Johnny Rigney vs Boots Poffenberger | Sixth | 4 out |
| Saturday, April 30 |
| » Defeated Indians (8-3), 5-3 | League Park II (1-0) | 5-6 | Won 2 |
| » Starters: Vern Kennedy vs Willis Hudlin | Sixth | 3 out |
| Sunday, May 1 |
| » Lost to Indians (9-3), 4-3 | Cleveland Stadium (0-1) | 5-7 | |
| » Starters: Elden Auker vs Mel Harder | Sixth | 4 out |
| Monday, May 2 |
| » Lost to Indians (10-3), 11-3 | League Park II (1-1) | 5-8 | Lost 2 |
| » Starters: Jake Wade vs Johnny Allen | Sixth | 5 out |
| Tuesday, May 3 |
| » Lost to Red Sox (8-6), 4-3 | Fenway Park (0-1) | 5-9 | Lost 3 |
| » Starters: Roxie Lawson vs Lefty Grove | Seventh | 6 out |
| Wednesday, May 4 |
| » Defeated Red Sox (8-7), 4-1 | Fenway Park (1-1) | 6-9 | |
| » Starters: Boots Poffenberger vs Jack Wilson | Sixth | 5 out |
| Future Tiger Howie Koplitz is born in Oshkosh, WI. |
| Thursday, May 5 |
| » Defeated Red Sox (8-8), 7-5 | Fenway Park (2-1) | 7-9 | Won 2 |
| » Starters: Vern Kennedy vs Fritz Ostermueller | Sixth | 4 out |
| Saturday, May 7 |
| » Lost to Yankees (12-7), 12-8 | Yankee Stadium (0-1) | 7-10 | |
| » Starters: Elden Auker vs Lefty Gomez | Fifth | 5½ out |
| Sunday, May 8 |
| » Lost to Athletics (6-12), 7-6 | Shibe Park (0-1) | 7-11 | Lost 2 |
| » Starters: Schoolboy Rowe vs Lynn Nelson | Fifth | 5½ out |
| Wednesday, May 11 |
| » Defeated Senators (15-8), 4-1 | Griffith Stadium (1-0) | 8-11 | |
| » Starters: Vern Kennedy vs Harry Kelley | Fourth | 5 out |
| Thursday, May 12 |
| » Lost to Senators (16-8), 7-6 | Griffith Stadium (1-1) | 8-12 | |
| » Starters: Roxie Lawson vs Jimmie DeShong | Fourth | 6 out |
| Friday, May 13 |
| » Defeated Browns (6-17), 7-5 | Tiger Stadium (2-3) | 9-12 | |
| » Starters: Jim Walkup vs George Gill | Fourth | 5 out |
| Sunday, May 15 |
| » Lost to Browns (7-17), 4-1 | Tiger Stadium (2-4) | 9-13 | |
| » Starters: Oral Hildebrand vs Elden Auker | Fifth | 6 out |
| Monday, May 16 |
| » Defeated Senators (16-12), 13-7 | Tiger Stadium (3-4) | 10-13 | |
| » Starters: Ken Chase vs Vern Kennedy | Fifth | 5½ out |
| Wednesday, May 18 |
| » Lost to Senators (17-12), 5-1 | Tiger Stadium (3-5) | 10-14 | |
| » Starters: Wes Ferrell vs Boots Poffenberger | Sixth | 6 out |
| Thursday, May 19 |
| » Defeated Athletics (7-17), 6-2 | Tiger Stadium (4-5) | 11-14 | |
| » Starters: Lynn Nelson vs George Gill | Sixth | 6 out |
| Friday, May 20 |
| » Lost to Athletics (8-17), 5-2 | Tiger Stadium (4-6) | 11-15 | |
| » Starters: Bud Thomas vs Schoolboy Rowe | Sixth | 7 out |
| Saturday, May 21 |
| » Defeated Athletics (8-18), 7-5 | Tiger Stadium (5-6) | 12-15 | |
| » Starters: George Caster vs Vern Kennedy | Fifth | 6 out |
| Sunday, May 22 |
| » Defeated Red Sox (17-11), 4-3 | Tiger Stadium (6-6) | 13-15 | Won 2 |
| » Starters: Jack Wilson vs Boots Poffenberger | Fifth | 6 out |
| Tuesday, May 24 |
| » Lost to Red Sox (18-11), 5-4 | Tiger Stadium (6-7) | 13-16 | |
| » Starters: Lefty Grove vs Elden Auker | Sixth | 7 out |
| Wednesday, May 25 |
| » Defeated Yankees (16-12), 7-3 | Tiger Stadium (7-7) | 14-16 | |
| » Starters: Joe Beggs vs George Gill | Sixth | 7 out |
| Thursday, May 26 |
| » Lost to Yankees (17-12), 5-1 | Tiger Stadium (7-8) | 14-17 | |
| » Starters: Red Ruffing vs Schoolboy Rowe | Sixth | 7 out |
| Friday, May 27 |
| » Defeated White Sox (12-14), 5-2 | Comiskey Park I (2-2) | 15-17 | |
| » Starters: Vern Kennedy vs Frank Gabler | Fifth | 6½ out |
| Saturday, May 28 |
| » Defeated White Sox (12-15), 9-1 | Comiskey Park I (3-2) | 16-17 | Won 2 |
| » Starters: Tommy Bridges vs Bill Cox | Fifth | 6 out |
| Sunday, May 29 |
| » Defeated White Sox (12-16), 2-1 | Comiskey Park I (4-2) | 17-17 | Won 3 |
| » Starters: Boots Poffenberger vs Monty Stratton | Fifth | 5 out |
| Monday, May 30 |
| » Defeated Browns (10-23), 10-9 | Tiger Stadium (8-8) | 18-17 | Won 4 |
| » Starters: Lefty Mills vs George Gill | Fifth | 6 out |
| » Lost to Browns (11-23), 3-0 | Tiger Stadium (8-9) | 18-18 | |
| » Starters: Les Tietje vs Roxie Lawson | Fifth | 6 out |
| Wednesday, June 1 |
| » Defeated Yankees (20-15), 8-4 | Yankee Stadium (1-1) | 19-18 | |
| » Starters: Vern Kennedy vs Steve Sundra | Fifth | 5 out |
| Thursday, June 2 |
| » Lost to Yankees (21-15), 5-4 | Yankee Stadium (1-2) | 19-19 | |
| » Starters: Boots Poffenberger vs Spud Chandler | Fifth | 6½ out |
| » Lost to Yankees (22-15), 5-2 | Yankee Stadium (1-3) | 19-20 | Lost 2 |
| » Starters: Elden Auker vs Monte Pearson | Fifth | 6½ out |
| Future Tiger Gene Michael is born in Kent, OH. |
| Friday, June 3 |
| » Lost to Yankees (23-15), 5-1 | Yankee Stadium (1-4) | 19-21 | Lost 3 |
| » Starters: George Gill vs Red Ruffing | Fifth | 7½ out |
| Saturday, June 4 |
| » Lost to Red Sox (22-17), 5-3 | Fenway Park (2-2) | 19-22 | Lost 4 |
| » Starters: Tommy Bridges vs Lefty Grove | Fifth | 8½ out |
| Sunday, June 5 |
| » Defeated Red Sox (22-18), 10-4 | Fenway Park (3-2) | 20-22 | |
| » Starters: Vern Kennedy vs Jack Wilson | Fifth | 8½ out |
| Monday, June 6 |
| » Lost to Red Sox (23-18), 8-7 | Fenway Park (3-3) | 20-23 | |
| » Starters: Boots Poffenberger vs Charlie Wagner | Fifth | 8½ out |
| Tuesday, June 7 |
| » Defeated Athletics (17-24), 5-4 | Shibe Park (1-1) | 21-23 | |
| » Starters: George Gill vs George Caster | Fifth | 8½ out |
| Wednesday, June 8 |
| » Defeated Athletics (17-25), 5-1 | Shibe Park (2-1) | 22-23 | Won 2 |
| » Starters: Tommy Bridges vs Bud Thomas | Fourth | 7½ out |
| Thursday, June 9 |
| » Lost to Athletics (18-25), 8-5 | Shibe Park (2-2) | 22-24 | |
| » Starters: Vern Kennedy vs Eddie Smith | Fourth | 7½ out |
| Friday, June 10 |
| » Defeated Senators (27-23), 7-6 | Griffith Stadium (2-1) | 23-24 | |
| » Starters: Elden Auker vs Ken Chase | Fifth | 6½ out |
| Saturday, June 11 |
| » Defeated Senators (27-24), 7-2 | Griffith Stadium (3-1) | 24-24 | Won 2 |
| » Starters: Roxie Lawson vs Dutch Leonard | Fifth | 6 out |
| Sunday, June 12 |
| » Defeated Senators (27-25), 18-12 | Griffith Stadium (4-1) | 25-24 | Won 3 |
| » Starters: Boots Poffenberger vs Wes Ferrell | Fifth | 5 out |
| Tuesday, June 14 |
| » Lost to Athletics (22-26), 8-2 | Tiger Stadium (8-10) | 25-25 | |
| » Starters: Lynn Nelson vs Vern Kennedy | Fifth | 5 out |
| Wednesday, June 15 |
| » Lost to Athletics (23-26), 7-6 | Tiger Stadium (8-11) | 25-26 | Lost 2 |
| » Starters: George Caster vs George Gill | Fifth | 6 out |
| Thursday, June 16 |
| » Defeated Athletics (23-27), 12-3 | Tiger Stadium (9-11) | 26-26 | |
| » Starters: Bud Thomas vs Tommy Bridges | Fifth | 6 out |
| » Major-league debuts: Dave Smith (Athletics) |
| Friday, June 17 |
| » Lost to Senators (29-27), 12-10 | Tiger Stadium (9-12) | 26-27 | |
| » Starters: Wes Ferrell vs Elden Auker | Fifth | 6½ out |
| » Defeated Senators (29-28), 4-3 | Tiger Stadium (10-12) | 27-27 | |
| » Starters: Dutch Leonard vs Roxie Lawson | Fifth | 6½ out |
| Saturday, June 18 |
| » Defeated Senators (29-29), 5-3 | Tiger Stadium (11-12) | 28-27 | Won 2 |
| » Starters: Jimmie DeShong vs Harry Eisenstat | Fourth | 5½ out |
| Sunday, June 19 |
| » Lost to Senators (30-29), 10-6 | Tiger Stadium (11-13) | 28-28 | |
| » Starters: Ken Chase vs Vern Kennedy | Fifth | 6½ out |
| Tuesday, June 21 |
| » Lost to Red Sox (33-22), 8-3 | Tiger Stadium (11-14) | 28-29 | Lost 2 |
| » Starters: Jack Wilson vs Tommy Bridges | Fifth | 7 out |
| » Defeated Red Sox (33-23), 5-4 | Tiger Stadium (12-14) | 29-29 | |
| » Starters: Charlie Wagner vs Roxie Lawson | Fifth | 7 out |
| Wednesday, June 22 |
| » Defeated Red Sox (33-24), 8-3 | Tiger Stadium (13-14) | 30-29 | Won 2 |
| » Starters: Lefty Grove vs Vern Kennedy | Fifth | 7½ out |
| Thursday, June 23 |
| » Defeated Red Sox (33-25), 10-2 | Tiger Stadium (14-14) | 31-29 | Won 3 |
| » Starters: Johnny Marcum vs George Gill | Fourth | 6½ out |
| Friday, June 24 |
| » Defeated Yankees (32-25), 12-8 | Tiger Stadium (15-14) | 32-29 | Won 4 |
| » Starters: Spud Chandler vs Harry Eisenstat | Fourth | 6½ out |
| Saturday, June 25 |
| » Lost to Yankees (33-25), 9-3 | Tiger Stadium (15-15) | 32-30 | |
| » Starters: Red Ruffing vs Roxie Lawson | Fourth | 7 out |
| Sunday, June 26 |
| » Lost to Yankees (34-25), 10-3 | Tiger Stadium (15-16) | 32-31 | Lost 2 |
| » Starters: Monte Pearson vs Vern Kennedy | Fifth | 7½ out |
| Tuesday, June 28 |
| » Lost to Indians (39-21), 5-4 | League Park II (1-2) | 32-32 | Lost 3 |
| » Starters: Tommy Bridges vs Johnny Allen | Fifth | 9 out |
| Wednesday, June 29 |
| » Defeated Indians (39-22), 4-3 | League Park II (2-2) | 33-32 | |
| » Starters: Elden Auker vs Mel Harder | Fifth | 8 out |
| Thursday, June 30 |
| » Lost to Indians (40-22), 10-9 | League Park II (2-3) | 33-33 | |
| » Starters: Vern Kennedy vs Bob Feller | Fifth | 9 out |
| Saturday, July 2 |
| » Lost to Browns (20-42), 13-5 | Sportsman's Park III (2-2) | 33-34 | Lost 2 |
| » Starters: Roxie Lawson vs Lefty Mills | Fourth | 9½ out |
| Sunday, July 3 |
| » Lost to Browns (21-42), 6-5 | Sportsman's Park III (2-3) | 33-35 | Lost 3 |
| » Starters: Vern Kennedy vs Oral Hildebrand | Fifth | 10½ out |
| » Lost to Browns (22-42), 6-2 | Sportsman's Park III (2-4) | 33-36 | Lost 4 |
| » Starters: George Gill vs Bobo Newsom | Fifth | 10½ out |
| Monday, July 4 |
| » Defeated Indians (41-24), 7-3 | Tiger Stadium (16-16) | 34-36 | |
| » Starters: Bob Feller vs Elden Auker | Third | 8½ out |
| » Defeated Indians (41-25), 5-2 | Tiger Stadium (17-16) | 35-36 | Won 2 |
| » Starters: Mel Harder vs Harry Eisenstat | Third | 8½ out |
| Friday, July 8 |
| » Defeated White Sox (27-35), 7-5 | Tiger Stadium (18-16) | 36-36 | Won 3 |
| » Starters: Monty Stratton vs Vern Kennedy | Fourth | 9 out |
| » Lost to White Sox (28-35), 5-3 | Tiger Stadium (18-17) | 36-37 | |
| » Starters: Thornton Lee vs Boots Poffenberger | Fourth | 9 out |
| Saturday, July 9 |
| » Defeated White Sox (28-36), 4-0 | Tiger Stadium (19-17) | 37-37 | |
| » Starters: John Whitehead vs Elden Auker | Fourth | 9 out |
| Sunday, July 10 |
| » Lost to White Sox (29-36), 5-4 | Tiger Stadium (19-18) | 37-38 | |
| » Starters: Ted Lyons vs Harry Eisenstat | Fifth | 10 out |
| Wednesday, July 13 |
| » Lost to Red Sox (42-29), 7-4 | Fenway Park (3-4) | 37-39 | Lost 2 |
| » Starters: Vern Kennedy vs Emerson Dickman | Fifth | 9½ out |
| » Defeated Red Sox (42-30), 9-5 | Fenway Park (4-4) | 38-39 | |
| » Starters: Elden Auker vs Jim Bagby | Fifth | 9½ out |
| Thursday, July 14 |
| » Lost to Red Sox (43-30), 12-1 | Fenway Park (4-5) | 38-40 | |
| » Starters: George Gill vs Lefty Grove | Fifth | 10½ out |
| Friday, July 15 |
| » Lost to Yankees (47-27), 3-0 | Yankee Stadium (1-5) | 38-41 | Lost 2 |
| » Starters: Boots Poffenberger vs Lefty Gomez | Fifth | 11½ out |
| Saturday, July 16 |
| » Lost to Yankees (48-27), 7-5 | Yankee Stadium (1-6) | 38-42 | Lost 3 |
| » Starters: Harry Eisenstat vs Red Ruffing | Fifth | 12½ out |
| Sunday, July 17 |
| » Lost to Yankees (49-27), 16-3 | Yankee Stadium (1-7) | 38-43 | Lost 4 |
| » Starters: Elden Auker vs Spud Chandler | Fifth | 13½ out |
| Tuesday, July 19 |
| » Lost to Senators (43-40), 4-3 | Griffith Stadium (4-2) | 38-44 | Lost 5 |
| » Starters: Vern Kennedy vs Ken Chase | Sixth | 13½ out |
| Wednesday, July 20 |
| » Lost to Senators (44-40), 7-2 | Griffith Stadium (4-3) | 38-45 | Lost 6 |
| » Starters: Boots Poffenberger vs Wes Ferrell | Sixth | 14 out |
| Thursday, July 21 |
| » Lost to Senators (45-40), 4-3 | Griffith Stadium (4-4) | 38-46 | Lost 7 |
| » Starters: Harry Eisenstat vs Monte Weaver | Sixth | 14½ out |
| Sunday, July 24 |
| » Defeated Athletics (29-47), 7-6 | Shibe Park (3-2) | 39-46 | |
| » Starters: Elden Auker vs Buck Ross | Sixth | 13½ out |
| » Defeated Athletics (29-48), 7-3 | Shibe Park (4-2) | 40-46 | Won 2 |
| » Starters: Tommy Bridges vs George Caster | Sixth | 13½ out |
| Tuesday, July 26 |
| » Defeated Senators (46-43), 6-5 | Tiger Stadium (20-18) | 41-46 | Won 3 |
| » Starters: Wes Ferrell vs Vern Kennedy | Sixth | 14 out |
| Wednesday, July 27 |
| » Defeated Senators (46-44), 9-4 | Tiger Stadium (21-18) | 42-46 | Won 4 |
| » Starters: Monte Weaver vs Roxie Lawson | Fifth | 14 out |
| Thursday, July 28 |
| » Defeated Senators (46-45), 12-4 | Tiger Stadium (22-18) | 43-46 | Won 5 |
| » Starters: Jimmie DeShong vs George Gill | Fifth | 13 out |
| Friday, July 29 |
| » Defeated Athletics (29-51), 9-2 | Tiger Stadium (23-18) | 44-46 | Won 6 |
| » Starters: Al Williams vs Elden Auker | Fifth | 13 out |
| Future Tiger Don Wert is born in Strasburg, PA. |
| Saturday, July 30 |
| » Defeated Athletics (29-52), 10-7 | Tiger Stadium (24-18) | 45-46 | Won 7 |
| » Starters: Eddie Smith vs Tommy Bridges | Fourth | 12½ out |
| » Defeated Athletics (29-53), 8-7 | Tiger Stadium (25-18) | 46-46 | Won 8 |
| » Starters: George Caster vs Boots Poffenberger | Fourth | 12½ out |
| Monday, August 1 |
| » Lost to Athletics (30-53), 4-0 | Tiger Stadium (25-19) | 46-47 | |
| » Starters: Buck Ross vs Roxie Lawson | Fifth | 14 out |
| Tuesday, August 2 |
| » Defeated Yankees (57-31), 4-3 | Tiger Stadium (26-19) | 47-47 | |
| » Starters: Lefty Gomez vs George Gill | Fifth | 13 out |
| Former Tiger Jim Curry dies in Grenloch, NJ at the age of 46. |
| Wednesday, August 3 |
| » Lost to Yankees (58-31), 10-7 | Tiger Stadium (26-20) | 47-48 | |
| » Starters: Red Ruffing vs Elden Auker | Fifth | 14 out |
| Thursday, August 4 |
| » Lost to Yankees (59-31), 8-4 | Tiger Stadium (26-21) | 47-49 | Lost 2 |
| » Starters: Monte Pearson vs Vern Kennedy | Fifth | 15 out |
| Future Tiger Ray Oyler is born in Indianapolis, IN. |
| Friday, August 5 |
| » Lost to Red Sox (53-37), 9-8 | Tiger Stadium (26-22) | 47-50 | Lost 3 |
| » Starters: Lefty Grove vs Elden Auker | Fifth | 16 out |
| Saturday, August 6 |
| » Lost to Red Sox (54-37), 14-8 | Tiger Stadium (26-23) | 47-51 | Lost 4 |
| » Starters: Emerson Dickman vs Roxie Lawson | Fifth | 17 out |
| Sunday, August 7 |
| » Defeated Red Sox (54-38), 7-3 | Tiger Stadium (27-23) | 48-51 | |
| » Manager: Del Baker |
| » Starters: Jack Wilson vs George Gill | Fifth | 17 out |
| Tuesday, August 9 |
| » Defeated White Sox (39-50), 4-1 | Comiskey Park I (5-2) | 49-51 | Won 2 |
| » Starters: Tommy Bridges vs Jack Knott | Fifth | 16 out |
| Wednesday, August 10 |
| » Lost to White Sox (40-50), 8-7 | Comiskey Park I (5-3) | 49-52 | |
| » Starters: Elden Auker vs Thornton Lee | Fifth | 17 out |
| Thursday, August 11 |
| » Lost to White Sox (41-50), 13-1 | Comiskey Park I (5-4) | 49-53 | Lost 2 |
| » Starters: Roxie Lawson vs Monty Stratton | Fifth | 18 out |
| Saturday, August 13 |
| » Lost to Browns (35-65), 6-3 | Sportsman's Park III (2-5) | 49-54 | Lost 3 |
| » Starters: George Gill vs Bill Cox | Fifth | 19 out |
| Sunday, August 14 |
| » Lost to Browns (36-65), 7-1 | Sportsman's Park III (2-6) | 49-55 | Lost 4 |
| » Starters: Vern Kennedy vs Bobo Newsom | Fifth | 20½ out |
| » Tied Browns, 3-3 | Sportsman's Park III (2-6) | 49-55 | |
| » Starters: Elden Auker vs Lefty Mills | Fifth | 20½ out |
| Wednesday, August 17 |
| » Defeated White Sox (43-54), 4-3 | Tiger Stadium (28-23) | 50-55 | |
| » Starters: Ted Lyons vs Tommy Bridges | Fifth | 20½ out |
| » Defeated White Sox (43-55), 3-2 | Tiger Stadium (29-23) | 51-55 | Won 2 |
| » Starters: Jack Knott vs Al Benton | Fifth | 20½ out |
| Thursday, August 18 |
| » Defeated White Sox (43-56), 5-1 | Tiger Stadium (30-23) | 52-55 | Won 3 |
| » Starters: John Whitehead vs George Gill | Fifth | 20 out |
| Friday, August 19 |
| » Defeated Browns (38-67), 8-7 | Tiger Stadium (31-23) | 53-55 | Won 4 |
| » Starters: Oral Hildebrand vs Vern Kennedy | Fifth | 19½ out |
| » Defeated Browns (38-68), 7-4 | Tiger Stadium (32-23) | 54-55 | Won 5 |
| » Starters: Lefty Mills vs Elden Auker | Fifth | 19½ out |
| Saturday, August 20 |
| » Defeated Browns (38-69), 6-4 | Tiger Stadium (33-23) | 55-55 | Won 6 |
| » Starters: Bill Cox vs Roxie Lawson | Fourth | 19½ out |
| Sunday, August 21 |
| » Lost to Browns (39-69), 9-4 | Tiger Stadium (33-24) | 55-56 | |
| » Starters: Bobo Newsom vs Al Benton | Fifth | 21 out |
| Tuesday, August 23 |
| » Defeated Athletics (38-71), 13-5 | Shibe Park (5-2) | 56-56 | |
| » Starters: Tommy Bridges vs Lynn Nelson | Fifth | 20 out |
| » Defeated Athletics (38-72), 8-3 | Shibe Park (6-2) | 57-56 | Won 2 |
| » Starters: George Gill vs Bud Thomas | Fifth | 20 out |
| Wednesday, August 24 |
| » Lost to Athletics (39-72), 10-5 | Shibe Park (6-3) | 57-57 | |
| » Starters: Elden Auker vs Nels Potter | Fifth | 21 out |
| » Lost to Athletics (40-72), 11-2 | Shibe Park (6-4) | 57-58 | Lost 2 |
| » Starters: Roxie Lawson vs George Caster | Fifth | 21 out |
| Thursday, August 25 |
| » Lost to Senators (60-57), 8-2 | Griffith Stadium (4-5) | 57-59 | Lost 3 |
| » Starters: Harry Eisenstat vs Pete Appleton | Fifth | 22½ out |
| Friday, August 26 |
| » Defeated Senators (60-58), 9-3 | Griffith Stadium (5-5) | 58-59 | |
| » Starters: Al Benton vs Harry Kelley | Fifth | 22 out |
| Saturday, August 27 |
| » Defeated Senators (60-59), 12-11 | Griffith Stadium (6-5) | 59-59 | Won 2 |
| » Starters: Roxie Lawson vs Dutch Leonard | Fifth | 22½ out |
| Sunday, August 28 |
| » Defeated Red Sox (68-48), 4-3 | Fenway Park (5-5) | 60-59 | Won 3 |
| » Starters: Tommy Bridges vs Emerson Dickman | Fourth | 22½ out |
| Monday, August 29 |
| » Defeated Red Sox (68-49), 15-1 | Fenway Park (6-5) | 61-59 | Won 4 |
| » Starters: Elden Auker vs Jack Wilson | Fourth | 22½ out |
| Tuesday, August 30 |
| » Lost to Yankees (85-37), 3-1 | Yankee Stadium (1-8) | 61-60 | |
| » Starters: George Gill vs Spud Chandler | Fourth | 23½ out |
| Wednesday, August 31 |
| » Defeated Yankees (85-38), 12-6 | Yankee Stadium (2-8) | 62-60 | |
| » Starters: Al Benton vs Steve Sundra | Fourth | 22½ out |
| Thursday, September 1 |
| » Defeated Yankees (85-39), 6-3 | Yankee Stadium (3-8) | 63-60 | Won 2 |
| » Starters: Slick Coffman vs Monte Pearson | Fourth | 21½ out |
| Saturday, September 3 |
| » Defeated White Sox (52-68), 11-4 | Comiskey Park I (6-4) | 64-60 | Won 3 |
| » Starters: Tommy Bridges vs Jack Knott | Fourth | 21 out |
| Sunday, September 4 |
| » Lost to White Sox (53-68), 2-1 | Comiskey Park I (6-5) | 64-61 | |
| » Starters: Al Benton vs Johnny Rigney | Fourth | 22 out |
| » Major-league debuts: Mike Tresh (White Sox) |
| Monday, September 5 |
| » Lost to Browns (45-79), 3-2 | Sportsman's Park III (2-7) | 64-62 | Lost 2 |
| » Starters: George Gill vs Lefty Mills | Fourth | 23 out |
| » Defeated Browns (45-80), 9-3 | Sportsman's Park III (3-7) | 65-62 | |
| » Starters: Elden Auker vs Bobo Newsom | Fourth | 23 out |
| Tuesday, September 6 |
| » Lost to Indians (74-53), 6-0 | Tiger Stadium (33-25) | 65-63 | |
| » Starters: Bob Feller vs Harry Eisenstat | Third | 23½ out |
| Wednesday, September 7 |
| » Lost to Indians (75-53), 1-0 | Tiger Stadium (33-26) | 65-64 | Lost 2 |
| » Starters: Mel Harder vs Slick Coffman | Third | 23½ out |
| Thursday, September 8 |
| » Defeated Indians (75-54), 4-1 | League Park II (3-3) | 66-64 | |
| » Starters: Al Benton vs Earl Whitehill | Third | 23½ out |
| Friday, September 9 |
| » Defeated Indians (75-55), 11-5 | League Park II (4-3) | 67-64 | Won 2 |
| » Starters: Tommy Bridges vs Willis Hudlin | Third | 23½ out |
| » Major-league debuts: Lou Boudreau and Ray Mack (Indians) |
| Sunday, September 11 |
| » Defeated White Sox (54-71), 10-1 | Tiger Stadium (34-26) | 68-64 | Won 3 |
| » Starters: Ted Lyons vs George Gill | Fourth | 22½ out |
| » Defeated White Sox (54-72), 5-3 | Tiger Stadium (35-26) | 69-64 | Won 4 |
| » Starters: Johnny Rigney vs Slick Coffman | Fourth | 22½ out |
| Monday, September 12 |
| » Defeated White Sox (54-73), 4-3 | Tiger Stadium (36-26) | 70-64 | Won 5 |
| » Starters: Jack Knott vs Al Benton | Fourth | 22 out |
| Tuesday, September 13 |
| » Defeated Red Sox (76-57), 9-3 | Tiger Stadium (37-26) | 71-64 | Won 6 |
| » Starters: Bill Harris vs Vern Kennedy | Fourth | 22 out |
| Wednesday, September 14 |
| » Lost to Red Sox (77-57), 9-2 | Tiger Stadium (37-27) | 71-65 | |
| » Starters: Joe Heving vs Tommy Bridges | Fourth | 22½ out |
| » Major-league debuts: George Archie and Benny McCoy (Tigers) |
| Thursday, September 15 |
| » Defeated Yankees (93-43), 6-4 | Tiger Stadium (38-27) | 72-65 | |
| » Starters: Bump Hadley vs Slick Coffman | Fourth | 21½ out |
| Friday, September 16 |
| » Lost to Yankees (94-43), 6-4 | Tiger Stadium (38-28) | 72-66 | |
| » Starters: Lefty Gomez vs George Gill | Fourth | 22½ out |
| Saturday, September 17 |
| » Defeated Yankees (94-44), 7-3 | Tiger Stadium (39-28) | 73-66 | |
| » Starters: Monte Pearson vs Al Benton | Fourth | 21½ out |
| Sunday, September 18 |
| » Defeated Senators (70-71), 8-1 | Tiger Stadium (40-28) | 74-66 | Won 2 |
| » Starters: Ken Chase vs Tommy Bridges | Fourth | 20 out |
| Monday, September 19 |
| » Lost to Senators (71-71), 12-2 | Tiger Stadium (40-29) | 74-67 | |
| » Starters: Pete Appleton vs Vern Kennedy | Fourth | 20 out |
| » Major-league debuts: Bob Harris (Tigers) |
| Wednesday, September 21 |
| » Defeated Athletics (51-92), 8-6 | Tiger Stadium (41-29) | 75-67 | |
| » Starters: Randy Gumpert vs Slick Coffman | Fourth | 18 out |
| » Defeated Athletics (51-93), 3-0 | Tiger Stadium (42-29) | 76-67 | Won 2 |
| » Starters: Buck Ross vs Boots Poffenberger | Fourth | 18 out |
| Friday, September 23 |
| » Lost to Indians (82-61), 8-1 | Tiger Stadium (42-30) | 76-68 | |
| » Starters: Bob Feller vs George Gill | Fourth | 19½ out |
| » Lost to Indians (83-61), 6-5 | Tiger Stadium (42-31) | 76-69 | Lost 2 |
| » Starters: Earl Whitehill vs Al Benton | Fourth | 19½ out |
| Saturday, September 24 |
| » Defeated Indians (83-62), 7-6 | Tiger Stadium (43-31) | 77-69 | |
| » Starters: Mel Harder vs Tommy Bridges | Fourth | 18½ out |
| Sunday, September 25 |
| » Defeated Indians (83-63), 7-5 | Tiger Stadium (44-31) | 78-69 | Won 2 |
| » Starters: Denny Galehouse vs Boots Poffenberger | Fourth | 17½ out |
| Tuesday, September 27 |
| » Defeated Browns (53-91), 5-4 | Tiger Stadium (45-31) | 79-69 | Won 3 |
| » Starters: Jim Walkup vs Al Benton | Fourth | 17½ out |
| » Defeated Browns (53-92), 10-2 | Tiger Stadium (46-31) | 80-69 | Won 4 |
| » Starters: Bill Cox vs Slick Coffman | Fourth | 17½ out |
| Wednesday, September 28 |
| » Defeated Browns (53-93), 12-0 | Tiger Stadium (47-31) | 81-69 | Won 5 |
| » Starters: Lefty Mills vs George Gill | Fourth | 16½ out |
| Thursday, September 29 |
| » Defeated Browns (53-94), 6-2 | Tiger Stadium (48-31) | 82-69 | Won 6 |
| » Starters: Bobo Newsom vs Tommy Bridges | Fourth | 16½ out |
| Saturday, October 1 |
| » Lost to Indians (86-64), 5-0 | League Park II (4-4) | 82-70 | |
| » Starters: Boots Poffenberger vs Denny Galehouse | Fourth | 16½ out |
| Sunday, October 2 |
| » Defeated Indians (86-65), 4-1 | Cleveland Stadium (1-1) | 83-70 | |
| » Starters: Harry Eisenstat vs Bob Feller | Fourth | 16 out |
| » Defeated Indians (86-66), 10-8 | Cleveland Stadium (2-1) | 84-70 | Won 2 |
| » Starters: Bob Harris vs Johnny Humphries | Fourth | 16 out |
| Monday, October 31 |
| Future Tiger Jim Donohue is born in St. Louis, MO. |
| Sunday, December 25 |
| Future Tiger Jack Hamilton is born in Burlington, IA. |
Game information provided by Retrosheet (www.retrosheet.org) |
