| Tuesday, January 18 |
| Future Senator Curt Flood is born in Houston, TX. |
| Wednesday, January 19 |
| Former Senator Bill Everitt dies in Denver, CO at the age of 70. |
| Wednesday, March 30 |
| Future Senator Dave Baldwin is born in Tucson, AZ. |
| Tuesday, April 5 |
| Future Senator Ron Hansen is born in Oxford, NE. |
| Monday, April 18 |
| » Defeated Athletics (0-1), 12-8 | Griffith Stadium (1-0) | 1-0 | |
| » Starters: Harry Kelley vs Wes Ferrell | First | -- |
| » Major-league debuts: Taffy Wright (Senators) |
| Tuesday, April 19 |
| » Defeated Athletics (0-2), 9-2 | Griffith Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Bud Thomas vs Monte Weaver | First | -- |
| Wednesday, April 20 |
| » Defeated Athletics (0-3), 3-0 | Griffith Stadium (3-0) | 3-0 | Won 3 |
| » Starters: Buck Ross vs Dutch Leonard | First | -- |
| Thursday, April 21 |
| » Major-league debuts: Atley Donald (Yankees) |
| Friday, April 22 |
| » Lost to Yankees (2-3), 7-0 | Yankee Stadium (0-1) | 3-1 | |
| » Starters: Chief Hogsett vs Red Ruffing | First | -- |
| Future Senator John Orsino is born in Teaneck, NJ. |
| Saturday, April 23 |
| » Defeated Yankees (2-4), 7-4 | Yankee Stadium (1-1) | 4-1 | |
| » Starters: Wes Ferrell vs Lefty Gomez | First | -- |
| Sunday, April 24 |
| » Lost to Yankees (3-4), 4-3 | Yankee Stadium (1-2) | 4-2 | |
| » Starters: Monte Weaver vs Spud Chandler | Second | 1 out |
| Monday, April 25 |
| » Lost to Red Sox (5-2), 7-0 | Griffith Stadium (3-1) | 4-3 | Lost 2 |
| » Starters: Fritz Ostermueller vs Dutch Leonard | Third | 1½ out |
| Tuesday, April 26 |
| » Defeated Red Sox (5-3), 6-4 | Griffith Stadium (4-1) | 5-3 | |
| » Starters: Johnny Marcum vs Pete Appleton | Second | 1½ out |
| Wednesday, April 27 |
| » Defeated Red Sox (5-4), 5-2 | Griffith Stadium (5-1) | 6-3 | Won 2 |
| » Starters: Archie McKain vs Jimmie DeShong | Second | ½ out |
| Thursday, April 28 |
| » Defeated Athletics (2-7), 7-2 | Shibe Park (1-0) | 7-3 | Won 3 |
| » Starters: Wes Ferrell vs George Caster | Second | ½ out |
| Friday, April 29 |
| » Lost to Athletics (3-7), 7-6 | Shibe Park (1-1) | 7-4 | |
| » Starters: Monte Weaver vs Buck Ross | Second | 1½ out |
| Saturday, April 30 |
| » Lost to Yankees (7-6), 8-4 | Griffith Stadium (5-2) | 7-5 | Lost 2 |
| » Starters: Spud Chandler vs Dutch Leonard | Second | 1½ out |
| Sunday, May 1 |
| » Defeated Yankees (7-7), 4-3 | Griffith Stadium (6-2) | 8-5 | |
| » Starters: Lefty Gomez vs Chief Hogsett | Second | 1½ out |
| Monday, May 2 |
| » Lost to Yankees (8-7), 3-2 | Griffith Stadium (6-3) | 8-6 | |
| » Starters: Monte Pearson vs Jimmie DeShong | Second | 2½ out |
| Tuesday, May 3 |
| » Lost to Indians (11-3), 10-9 | Griffith Stadium (6-4) | 8-7 | Lost 2 |
| » Starters: Al Milnar vs Wes Ferrell | Fourth | 3½ out |
| Wednesday, May 4 |
| » Defeated Indians (11-4), 1-0 | Griffith Stadium (7-4) | 9-7 | |
| » Starters: Bob Feller vs Dutch Leonard | Third | 2½ out |
| Future Senator Howie Koplitz is born in Oshkosh, WI. |
| Thursday, May 5 |
| » Defeated Indians (11-5), 8-6 | Griffith Stadium (8-4) | 10-7 | Won 2 |
| » Starters: Mel Harder vs Chief Hogsett | Third | 1½ out |
| » Major-league debuts: Hank Helf (Indians) |
| Friday, May 6 |
| » Defeated White Sox (7-8), 4-3 | Griffith Stadium (9-4) | 11-7 | Won 3 |
| » Starters: Thornton Lee vs Monte Weaver | Second | 1½ out |
| Saturday, May 7 |
| » Defeated White Sox (7-9), 5-4 | Griffith Stadium (10-4) | 12-7 | Won 4 |
| » Starters: Ted Lyons vs Jimmie DeShong | Second | 1½ out |
| Sunday, May 8 |
| » Defeated Browns (5-14), 9-7 | Griffith Stadium (11-4) | 13-7 | Won 5 |
| » Starters: Russ VanAtta vs Wes Ferrell | Second | ½ out |
| Monday, May 9 |
| » Defeated Browns (5-15), 7-1 | Griffith Stadium (12-4) | 14-7 | Won 6 |
| » Starters: Oral Hildebrand vs Dutch Leonard | First | -- |
| Tuesday, May 10 |
| » Defeated Browns (5-16), 8-6 | Griffith Stadium (13-4) | 15-7 | Won 7 |
| » Starters: Bobo Newsom vs Chief Hogsett | First | -- |
| Wednesday, May 11 |
| » Lost to Tigers (8-11), 4-1 | Griffith Stadium (13-5) | 15-8 | |
| » Starters: Vern Kennedy vs Harry Kelley | Second | 1 out |
| Thursday, May 12 |
| » Defeated Tigers (8-12), 7-6 | Griffith Stadium (14-5) | 16-8 | |
| » Starters: Roxie Lawson vs Jimmie DeShong | First | -- |
| Friday, May 13 |
| » Lost to Red Sox (14-8), 10-0 | Fenway Park (0-1) | 16-9 | |
| » Starters: Wes Ferrell vs Jack Wilson | First | -- |
| Saturday, May 14 |
| » Lost to Red Sox (15-8), 10-9 | Fenway Park (0-2) | 16-10 | Lost 2 |
| » Starters: Dutch Leonard vs Fritz Ostermueller | Second | 1½ out |
| Sunday, May 15 |
| » Lost to Red Sox (16-8), 4-3 | Fenway Park (0-3) | 16-11 | Lost 3 |
| » Starters: Monte Weaver vs Lefty Grove | Third | 1½ out |
| Monday, May 16 |
| » Lost to Tigers (10-13), 13-7 | Tiger Stadium (0-1) | 16-12 | Lost 4 |
| » Starters: Ken Chase vs Vern Kennedy | Fourth | 2 out |
| Wednesday, May 18 |
| » Defeated Tigers (10-14), 5-1 | Tiger Stadium (1-1) | 17-12 | |
| » Starters: Wes Ferrell vs Boots Poffenberger | Fourth | 2½ out |
| Thursday, May 19 |
| » Lost to Indians (18-9), 15-3 | League Park II (0-1) | 17-13 | |
| » Starters: Jimmie DeShong vs Willis Hudlin | Fourth | 2½ out |
| Friday, May 20 |
| » Lost to Indians (19-9), 6-3 | League Park II (0-2) | 17-14 | Lost 2 |
| » Starters: Dutch Leonard vs Johnny Allen | Fourth | 3½ out |
| Saturday, May 21 |
| » Defeated Indians (19-10), 5-4 | League Park II (1-2) | 18-14 | |
| » Starters: Ken Chase vs Earl Whitehill | Fourth | 2½ out |
| Sunday, May 22 |
| » Lost to White Sox (10-12), 9-2 | Comiskey Park I (0-1) | 18-15 | |
| » Starters: Wes Ferrell vs Ted Lyons | Fourth | 3½ out |
| Tuesday, May 24 |
| » Lost to White Sox (11-12), 10-3 | Comiskey Park I (0-2) | 18-16 | Lost 2 |
| » Starters: Dutch Leonard vs Monty Stratton | Fourth | 4½ out |
| Wednesday, May 25 |
| » Lost to Browns (9-21), 4-3 | Sportsman's Park III (0-1) | 18-17 | Lost 3 |
| » Starters: Monte Weaver vs Lefty Mills | Fourth | 5½ out |
| Thursday, May 26 |
| » Defeated Browns (9-22), 12-10 | Sportsman's Park III (1-1) | 19-17 | |
| » Starters: Jimmie DeShong vs Bobo Newsom | Fourth | 4½ out |
| Saturday, May 28 |
| » Defeated Red Sox (19-13), 3-2 | Griffith Stadium (15-5) | 20-17 | Won 2 |
| » Starters: Jim Bagby vs Dutch Leonard | Fourth | 4 out |
| Sunday, May 29 |
| » Defeated Red Sox (19-14), 5-3 | Griffith Stadium (16-5) | 21-17 | Won 3 |
| » Starters: Emerson Dickman vs Wes Ferrell | Third | 3 out |
| Monday, May 30 |
| » Defeated Athletics (13-20), 9-4 | Shibe Park (2-1) | 22-17 | Won 4 |
| » Starters: Monte Weaver vs Al Williams | Third | 4 out |
| » Lost to Athletics (14-20), 9-1 | Shibe Park (2-2) | 22-18 | |
| » Starters: Ken Chase vs George Caster | Third | 4 out |
| Wednesday, June 1 |
| » Defeated White Sox (12-19), 5-4 | Griffith Stadium (17-5) | 23-18 | |
| » Starters: John Whitehead vs Jimmie DeShong | Third | 3 out |
| Thursday, June 2 |
| » Defeated White Sox (12-20), 7-1 | Griffith Stadium (18-5) | 24-18 | Won 2 |
| » Starters: Frank Gabler vs Dutch Leonard | Third | 3 out |
| Friday, June 3 |
| » Defeated White Sox (12-21), 5-1 | Griffith Stadium (19-5) | 25-18 | Won 3 |
| » Starters: Thornton Lee vs Wes Ferrell | Third | 3 out |
| Saturday, June 4 |
| » Lost to Indians (27-13), 11-4 | Griffith Stadium (19-6) | 25-19 | |
| » Starters: Bob Feller vs Chief Hogsett | Third | 4 out |
| Sunday, June 5 |
| » Lost to Indians (28-13), 5-4 | Griffith Stadium (19-7) | 25-20 | Lost 2 |
| » Starters: Mel Harder vs Pete Appleton | Third | 5 out |
| Monday, June 6 |
| » Defeated Indians (28-14), 5-4 | Griffith Stadium (20-7) | 26-20 | |
| » Starters: Earl Whitehill vs Ken Chase | Third | 4 out |
| Tuesday, June 7 |
| » Lost to Browns (13-26), 11-8 | Griffith Stadium (20-8) | 26-21 | |
| » Starters: Lefty Mills vs Dutch Leonard | Third | 5 out |
| Wednesday, June 8 |
| » Lost to Browns (14-26), 11-5 | Griffith Stadium (20-9) | 26-22 | Lost 2 |
| » Starters: Oral Hildebrand vs Wes Ferrell | Third | 5 out |
| Thursday, June 9 |
| » Defeated Browns (14-27), 6-4 | Griffith Stadium (21-9) | 27-22 | |
| » Starters: Russ VanAtta vs Jimmie DeShong | Third | 4 out |
| Friday, June 10 |
| » Lost to Tigers (23-24), 7-6 | Griffith Stadium (21-10) | 27-23 | |
| » Starters: Elden Auker vs Ken Chase | Fourth | 4 out |
| Saturday, June 11 |
| » Lost to Tigers (24-24), 7-2 | Griffith Stadium (21-11) | 27-24 | Lost 2 |
| » Starters: Roxie Lawson vs Dutch Leonard | Fourth | 4½ out |
| Sunday, June 12 |
| » Lost to Tigers (25-24), 18-12 | Griffith Stadium (21-12) | 27-25 | Lost 3 |
| » Starters: Boots Poffenberger vs Wes Ferrell | Fourth | 4½ out |
| Tuesday, June 14 |
| » Defeated Indians (29-19), 7-6 | League Park II (2-2) | 28-25 | |
| » Starters: Jimmie DeShong vs Johnny Humphries | Fourth | 3½ out |
| Wednesday, June 15 |
| » Lost to Indians (30-19), 6-4 | League Park II (2-3) | 28-26 | |
| » Starters: Ken Chase vs Earl Whitehill | Fourth | 4½ out |
| Thursday, June 16 |
| » Lost to Indians (31-19), 4-1 | League Park II (2-4) | 28-27 | Lost 2 |
| » Starters: Joe Krakauskas vs Bob Feller | Fourth | 5½ out |
| Friday, June 17 |
| » Defeated Tigers (26-27), 12-10 | Tiger Stadium (2-1) | 29-27 | |
| » Starters: Wes Ferrell vs Elden Auker | Fourth | 6 out |
| » Lost to Tigers (27-27), 4-3 | Tiger Stadium (2-2) | 29-28 | |
| » Starters: Dutch Leonard vs Roxie Lawson | Fourth | 6 out |
| Saturday, June 18 |
| » Lost to Tigers (28-27), 5-3 | Tiger Stadium (2-3) | 29-29 | Lost 2 |
| » Starters: Jimmie DeShong vs Harry Eisenstat | Fifth | 6 out |
| Sunday, June 19 |
| » Defeated Tigers (28-28), 10-6 | Tiger Stadium (3-3) | 30-29 | |
| » Starters: Ken Chase vs Vern Kennedy | Fourth | 6 out |
| Tuesday, June 21 |
| » Defeated White Sox (19-32), 7-0 | Comiskey Park I (1-2) | 31-29 | Won 2 |
| » Starters: Harry Kelley vs Thornton Lee | Fourth | 6 out |
| Wednesday, June 22 |
| » Lost to White Sox (20-32), 16-3 | Comiskey Park I (1-3) | 31-30 | |
| » Starters: Wes Ferrell vs Monty Stratton | Fourth | 7½ out |
| Thursday, June 23 |
| » Defeated White Sox (20-33), 12-0 | Comiskey Park I (2-3) | 32-30 | |
| » Starters: Dutch Leonard vs John Whitehead | Fifth | 6½ out |
| Friday, June 24 |
| Future Senator Don Mincher is born in Huntsville, AL. |
| Saturday, June 25 |
| » Lost to Browns (19-36), 12-9 | Sportsman's Park III (1-2) | 32-31 | |
| » Starters: Jimmie DeShong vs Oral Hildebrand | Fifth | 7½ out |
| Sunday, June 26 |
| » Defeated Browns (19-37), 9-1 | Sportsman's Park III (2-2) | 33-31 | |
| » Starters: Harry Kelley vs Lefty Mills | Fourth | 6½ out |
| » Defeated Browns (19-38), 7-2 | Sportsman's Park III (3-2) | 34-31 | Won 2 |
| » Starters: Wes Ferrell vs Bobo Newsom | Fourth | 6½ out |
| Wednesday, June 29 |
| » Lost to Red Sox (34-27), 6-4 | Fenway Park (0-4) | 34-32 | |
| » Starters: Dutch Leonard vs Johnny Marcum | Fourth | 7½ out |
| Thursday, June 30 |
| » Lost to Red Sox (35-27), 11-1 | Fenway Park (0-5) | 34-33 | Lost 2 |
| » Starters: Jimmie DeShong vs Jim Bagby | Fourth | 8½ out |
| Friday, July 1 |
| » Lost to Yankees (38-25), 8-0 | Yankee Stadium (1-3) | 34-34 | Lost 3 |
| » Starters: Harry Kelley vs Spud Chandler | Fifth | 9 out |
| Saturday, July 2 |
| » Lost to Yankees (39-25), 12-2 | Yankee Stadium (1-4) | 34-35 | Lost 4 |
| » Starters: Wes Ferrell vs Monte Pearson | Fifth | 9½ out |
| Sunday, July 3 |
| » Lost to Athletics (27-35), 3-0 | Shibe Park (2-3) | 34-36 | Lost 5 |
| » Starters: Dutch Leonard vs George Caster | Fourth | 9½ out |
| » Defeated Athletics (27-36), 14-2 | Shibe Park (3-3) | 35-36 | |
| » Starters: Monte Weaver vs Lynn Nelson | Fourth | 9½ out |
| Monday, July 4 |
| » Lost to Yankees (41-25), 10-5 | Griffith Stadium (21-13) | 35-37 | |
| » Starters: Red Ruffing vs Ken Chase | Fourth | 9 out |
| » Tied Yankees, 4-4 | Griffith Stadium (21-13) | 35-37 | |
| » Starters: Bump Hadley vs Chief Hogsett | Fourth | 9 out |
| Wednesday, July 6 |
| Future Senator Barry Shetrone is born in Baltimore, MD. |
| Friday, July 8 |
| » Defeated Athletics (27-39), 11-0 | Griffith Stadium (22-13) | 36-37 | |
| » Starters: Lynn Nelson vs Harry Kelley | Fourth | 9 out |
| Saturday, July 9 |
| » Defeated Athletics (27-40), 7-4 | Griffith Stadium (23-13) | 37-37 | Won 2 |
| » Starters: George Caster vs Wes Ferrell | Fourth | 9 out |
| Sunday, July 10 |
| » Defeated Athletics (27-41), 5-2 | Griffith Stadium (24-13) | 38-37 | Won 3 |
| » Starters: Bud Thomas vs Dutch Leonard | Fourth | 8½ out |
| » Defeated Athletics (27-42), 8-7 | Griffith Stadium (25-13) | 39-37 | Won 4 |
| » Starters: Buck Ross vs Monte Weaver | Fourth | 8½ out |
| Future Senator Mike Brumley is born in Granite, OK. |
| Tuesday, July 12 |
| » Defeated Indians (44-26), 9-8 | Griffith Stadium (26-13) | 40-37 | Won 5 |
| » Starters: Denny Galehouse vs Ken Chase | Fourth | 7½ out |
| Wednesday, July 13 |
| » Defeated Indians (44-27), 4-3 | Griffith Stadium (27-13) | 41-37 | Won 6 |
| » Starters: Bob Feller vs Harry Kelley | Fourth | 7 out |
| Thursday, July 14 |
| » Lost to Indians (45-27), 5-1 | Griffith Stadium (27-14) | 41-38 | |
| » Starters: Mel Harder vs Dutch Leonard | Fourth | 8 out |
| Friday, July 15 |
| » Lost to White Sox (32-37), 11-3 | Griffith Stadium (27-15) | 41-39 | Lost 2 |
| » Starters: Thornton Lee vs Wes Ferrell | Fourth | 9 out |
| Saturday, July 16 |
| » Defeated White Sox (32-38), 3-2 | Griffith Stadium (28-15) | 42-39 | |
| » Starters: Ted Lyons vs Monte Weaver | Fourth | 9 out |
| Sunday, July 17 |
| » Lost to White Sox (33-38), 12-1 | Griffith Stadium (28-16) | 42-40 | |
| » Starters: Monty Stratton vs Harry Kelley | Fourth | 10 out |
| Tuesday, July 19 |
| » Defeated Tigers (38-44), 4-3 | Griffith Stadium (29-16) | 43-40 | |
| » Starters: Vern Kennedy vs Ken Chase | Fourth | 9 out |
| Wednesday, July 20 |
| » Defeated Tigers (38-45), 7-2 | Griffith Stadium (30-16) | 44-40 | Won 2 |
| » Starters: Boots Poffenberger vs Wes Ferrell | Fourth | 8½ out |
| Thursday, July 21 |
| » Defeated Tigers (38-46), 4-3 | Griffith Stadium (31-16) | 45-40 | Won 3 |
| » Starters: Harry Eisenstat vs Monte Weaver | Fourth | 8 out |
| Friday, July 22 |
| » Lost to Browns (24-54), 9-7 | Griffith Stadium (31-17) | 45-41 | |
| » Starters: Lefty Mills vs Harry Kelley | Fourth | 8½ out |
| Sunday, July 24 |
| » Lost to Browns (25-54), 4-2 | Griffith Stadium (31-18) | 45-42 | Lost 2 |
| » Starters: Oral Hildebrand vs Ken Chase | Fourth | 8½ out |
| » Defeated Browns (25-55), 11-1 | Griffith Stadium (32-18) | 46-42 | |
| » Starters: Russ VanAtta vs Dutch Leonard | Fourth | 8½ out |
| Tuesday, July 26 |
| » Lost to Tigers (41-46), 6-5 | Tiger Stadium (3-4) | 46-43 | |
| » Starters: Wes Ferrell vs Vern Kennedy | Fourth | 10 out |
| Wednesday, July 27 |
| » Lost to Tigers (42-46), 9-4 | Tiger Stadium (3-5) | 46-44 | Lost 2 |
| » Starters: Monte Weaver vs Roxie Lawson | Fourth | 11 out |
| Thursday, July 28 |
| » Lost to Tigers (43-46), 12-4 | Tiger Stadium (3-6) | 46-45 | Lost 3 |
| » Starters: Jimmie DeShong vs George Gill | Fourth | 11 out |
| Friday, July 29 |
| » Lost to Indians (52-30), 12-4 | League Park II (2-5) | 46-46 | Lost 4 |
| » Starters: Chief Hogsett vs Johnny Allen | Fourth | 12 out |
| Future Senator Don Wert is born in Strasburg, PA. |
| Saturday, July 30 |
| » Lost to Indians (53-30), 8-5 | League Park II (2-6) | 46-47 | Lost 5 |
| » Starters: Ken Chase vs Mel Harder | Fifth | 13 out |
| Monday, August 1 |
| » Defeated Indians (53-31), 11-8 | League Park II (3-6) | 47-47 | |
| » Starters: Dutch Leonard vs Bob Feller | Fourth | 13½ out |
| Tuesday, August 2 |
| » Defeated Browns (28-60), 5-3 | Sportsman's Park III (4-2) | 48-47 | Won 2 |
| » Starters: Wes Ferrell vs Oral Hildebrand | Fourth | 12½ out |
| Wednesday, August 3 |
| » Lost to Browns (29-60), 5-3 | Sportsman's Park III (4-3) | 48-48 | |
| » Starters: Monte Weaver vs Bobo Newsom | Fourth | 13½ out |
| Thursday, August 4 |
| » Defeated Browns (29-61), 10-4 | Sportsman's Park III (5-3) | 49-48 | |
| » Starters: Harry Kelley vs Lefty Mills | Fourth | 13½ out |
| Saturday, August 6 |
| » Defeated White Sox (38-48), 7-1 | Comiskey Park I (3-3) | 50-48 | Won 2 |
| » Starters: Dutch Leonard vs Ted Lyons | Fourth | 14 out |
| Sunday, August 7 |
| » Lost to White Sox (39-48), 14-5 | Comiskey Park I (3-4) | 50-49 | |
| » Starters: Wes Ferrell vs Monty Stratton | Fourth | 14½ out |
| » Defeated White Sox (39-49), 12-5 | Comiskey Park I (4-4) | 51-49 | |
| » Starters: Monte Weaver vs Thornton Lee | Fourth | 14½ out |
| Tuesday, August 9 |
| » Defeated Yankees (62-32), 4-2 | Yankee Stadium (2-4) | 52-49 | Won 2 |
| » Starters: Ken Chase vs Spud Chandler | Fourth | 13½ out |
| Wednesday, August 10 |
| » Lost to Yankees (63-32), 12-11 | Yankee Stadium (2-5) | 52-50 | |
| » Starters: Chief Hogsett vs Monte Pearson | Fourth | 14½ out |
| Thursday, August 11 |
| » Lost to Yankees (64-32), 9-6 | Yankee Stadium (2-6) | 52-51 | Lost 2 |
| » Starters: Joe Krakauskas vs Lefty Gomez | Fourth | 15½ out |
| Friday, August 12 |
| » Defeated Red Sox (55-41), 13-1 | Griffith Stadium (33-18) | 53-51 | |
| » Starters: Jack Wilson vs Dutch Leonard | Fourth | 15 out |
| Saturday, August 13 |
| » Defeated Red Sox (55-42), 4-1 | Griffith Stadium (34-18) | 54-51 | Won 2 |
| » Starters: Fritz Ostermueller vs Monte Weaver | Fourth | 15 out |
| Sunday, August 14 |
| » Defeated Red Sox (55-43), 7-1 | Griffith Stadium (35-18) | 55-51 | Won 3 |
| » Starters: Bill Harris vs Harry Kelley | Fourth | 15½ out |
| Tuesday, August 16 |
| » Lost to Yankees (69-33), 16-1 | Griffith Stadium (35-19) | 55-52 | |
| » Starters: Lefty Gomez vs Ken Chase | Fourth | 17½ out |
| » Lost to Yankees (70-33), 6-2 | Griffith Stadium (35-20) | 55-53 | Lost 2 |
| » Starters: Red Ruffing vs Joe Krakauskas | Fourth | 17½ out |
| Wednesday, August 17 |
| Future Senator Dick Lines is born in Montreal, PQ. |
| Thursday, August 18 |
| » Lost to Yankees (71-33), 6-5 | Griffith Stadium (35-21) | 55-54 | Lost 3 |
| » Starters: Wes Ferrell vs Dutch Leonard | Fourth | 17½ out |
| » Defeated Yankees (71-34), 6-3 | Griffith Stadium (36-21) | 56-54 | |
| » Starters: Bump Hadley vs Harry Kelley | Fourth | 17½ out |
| Friday, August 19 |
| » Lost to Red Sox (59-44), 4-3 | Fenway Park (0-6) | 56-55 | |
| » Starters: Monte Weaver vs Fritz Ostermueller | Fourth | 18½ out |
| Saturday, August 20 |
| » Lost to Red Sox (60-44), 10-7 | Fenway Park (0-7) | 56-56 | Lost 2 |
| » Starters: Jimmie DeShong vs Archie McKain | Fifth | 19½ out |
| Sunday, August 21 |
| » Defeated Red Sox (60-45), 5-4 | Fenway Park (1-7) | 57-56 | |
| » Starters: Pete Appleton vs Jack Wilson | Fourth | 20½ out |
| » Lost to Red Sox (61-45), 7-2 | Fenway Park (1-8) | 57-57 | |
| » Starters: Harry Kelley vs Joe Heving | Fourth | 20½ out |
| Tuesday, August 23 |
| » Defeated Browns (39-70), 6-5 | Griffith Stadium (37-21) | 58-57 | |
| » Starters: Lefty Mills vs Dutch Leonard | Fourth | 20 out |
| Wednesday, August 24 |
| » Defeated Browns (39-71), 8-6 | Griffith Stadium (38-21) | 59-57 | Won 2 |
| » Starters: Bill Cox vs Monte Weaver | Fourth | 19½ out |
| Thursday, August 25 |
| » Defeated Tigers (57-59), 8-2 | Griffith Stadium (39-21) | 60-57 | Won 3 |
| » Starters: Harry Eisenstat vs Pete Appleton | Fourth | 20 out |
| Friday, August 26 |
| » Lost to Tigers (58-59), 9-3 | Griffith Stadium (39-22) | 60-58 | |
| » Starters: Al Benton vs Harry Kelley | Fourth | 20½ out |
| Saturday, August 27 |
| » Lost to Tigers (59-59), 12-11 | Griffith Stadium (39-23) | 60-59 | Lost 2 |
| » Starters: Roxie Lawson vs Dutch Leonard | Fourth | 22 out |
| Sunday, August 28 |
| » Lost to Indians (66-52), 6-5 | Griffith Stadium (39-24) | 60-60 | Lost 3 |
| » Starters: Mel Harder vs Monte Weaver | Fifth | 23 out |
| Monday, August 29 |
| » Defeated Indians (66-53), 6-4 | Griffith Stadium (40-24) | 61-60 | |
| » Starters: Earl Whitehill vs Ken Chase | Fifth | 23 out |
| Tuesday, August 30 |
| » Lost to White Sox (50-67), 3-2 | Griffith Stadium (40-25) | 61-61 | |
| » Starters: Johnny Rigney vs Pete Appleton | Fifth | 24 out |
| Wednesday, August 31 |
| » Lost to White Sox (51-67), 7-0 | Griffith Stadium (40-26) | 61-62 | Lost 2 |
| » Starters: John Whitehead vs Dutch Leonard | Fifth | 24 out |
| Thursday, September 1 |
| » Lost to White Sox (52-67), 11-6 | Griffith Stadium (40-27) | 61-63 | Lost 3 |
| » Starters: Thornton Lee vs Harry Kelley | Fifth | 24 out |
| Friday, September 2 |
| » Defeated Athletics (44-80), 4-2 | Shibe Park (4-3) | 62-63 | |
| » Starters: Ken Chase vs Nels Potter | Fifth | 24 out |
| Saturday, September 3 |
| » Defeated Athletics (44-81), 7-0 | Shibe Park (5-3) | 63-63 | Won 2 |
| » Starters: Joe Krakauskas vs George Caster | Fifth | 23 out |
| Sunday, September 4 |
| » Lost to Yankees (87-40), 7-4 | Yankee Stadium (2-7) | 63-64 | |
| » Starters: Chief Hogsett vs Bump Hadley | Fifth | 24 out |
| Monday, September 5 |
| » Lost to Red Sox (73-52), 14-4 | Griffith Stadium (40-28) | 63-65 | Lost 2 |
| » Starters: Fritz Ostermueller vs Pete Appleton | Fifth | 26 out |
| » Lost to Red Sox (74-52), 8-6 | Griffith Stadium (40-29) | 63-66 | Lost 3 |
| » Starters: Emerson Dickman vs Dutch Leonard | Fifth | 26 out |
| Tuesday, September 6 |
| » Defeated Red Sox (74-53), 7-5 | Griffith Stadium (41-29) | 64-66 | |
| » Starters: Jack Wilson vs Rene Monteagudo | Fourth | 25½ out |
| » Major-league debuts: Rene Monteagudo (Senators) |
| Wednesday, September 7 |
| » Lost to Athletics (46-84), 5-2 | Griffith Stadium (41-30) | 64-67 | |
| » Starters: George Caster vs Joe Krakauskas | Fourth | 25½ out |
| Thursday, September 8 |
| » Defeated Athletics (46-85), 5-2 | Griffith Stadium (42-30) | 65-67 | |
| » Starters: Bud Thomas vs Ken Chase | Fourth | 25½ out |
| Friday, September 9 |
| » Lost to Yankees (91-41), 2-0 | Griffith Stadium (42-31) | 65-68 | |
| » Starters: Bump Hadley vs Dutch Leonard | Fourth | 26½ out |
| Saturday, September 10 |
| » Lost to Yankees (92-41), 6-5 | Griffith Stadium (42-32) | 65-69 | Lost 2 |
| » Starters: Monte Pearson vs Rene Monteagudo | Fourth | 27½ out |
| Sunday, September 11 |
| » Defeated Yankees (92-42), 6-3 | Griffith Stadium (43-32) | 66-69 | |
| » Starters: Spud Chandler vs Joe Krakauskas | Fifth | 26½ out |
| Tuesday, September 13 |
| » Defeated White Sox (54-74), 7-1 | Comiskey Park I (5-4) | 67-69 | Won 2 |
| » Starters: Ken Chase vs Monty Stratton | Fifth | 27 out |
| » Lost to White Sox (55-74), 3-2 | Comiskey Park I (5-5) | 67-70 | |
| » Starters: Pete Appleton vs Thornton Lee | Fifth | 27 out |
| Wednesday, September 14 |
| » Major-league debuts: George Archie and Benny McCoy (Tigers) |
| Thursday, September 15 |
| » Defeated Browns (47-84), 6-4 | Sportsman's Park III (6-3) | 68-70 | |
| » Starters: Dutch Leonard vs Lefty Mills | Fifth | 26 out |
| Saturday, September 17 |
| » Defeated Browns (47-85), 10-9 | Sportsman's Park III (7-3) | 69-70 | Won 2 |
| » Starters: Rene Monteagudo vs Russ VanAtta | Fifth | 25 out |
| » Defeated Browns (47-86), 11-1 | Sportsman's Park III (8-3) | 70-70 | Won 3 |
| » Starters: Joe Krakauskas vs Emil Bildilli | Fifth | 25 out |
| » Major-league debuts: Mickey Livingston (Senators) |
| Sunday, September 18 |
| » Lost to Tigers (74-66), 8-1 | Tiger Stadium (3-7) | 70-71 | |
| » Starters: Ken Chase vs Tommy Bridges | Fifth | 24½ out |
| Monday, September 19 |
| » Defeated Tigers (74-67), 12-2 | Tiger Stadium (4-7) | 71-71 | |
| » Starters: Pete Appleton vs Vern Kennedy | Fifth | 23½ out |
| » Major-league debuts: Bob Harris (Tigers) |
| Tuesday, September 20 |
| » Lost to Indians (81-61), 9-1 | League Park II (3-7) | 71-72 | |
| » Starters: Dutch Leonard vs Denny Galehouse | Fifth | 23½ out |
| Saturday, September 24 |
| » Defeated Athletics (51-94), 7-3 | Shibe Park (6-3) | 72-72 | |
| » Starters: Joe Krakauskas vs George Caster | Fifth | 22½ out |
| Sunday, September 25 |
| » Lost to Athletics (52-94), 6-5 | Shibe Park (6-4) | 72-73 | |
| » Starters: Pete Appleton vs Jim Reninger | Fifth | 22 out |
| » Defeated Athletics (52-95), 5-4 | Shibe Park (7-4) | 73-73 | |
| » Starters: Ken Chase vs Bud Thomas | Fifth | 22 out |
| Tuesday, September 27 |
| » Lost to Yankees (97-51), 5-2 | Yankee Stadium (2-8) | 73-74 | |
| » Starters: Dutch Leonard vs Lefty Gomez | Fifth | 23½ out |
| Wednesday, September 28 |
| » Defeated Yankees (97-52), 4-1 | Yankee Stadium (3-8) | 74-74 | |
| » Starters: Joe Krakauskas vs Ivy Andrews | Fifth | 22½ out |
| Thursday, September 29 |
| » Lost to Red Sox (87-60), 13-5 | Fenway Park (1-9) | 74-75 | |
| » Starters: Pete Appleton vs Fritz Ostermueller | Fifth | 23½ out |
| Future Senator Mike McCormick is born in Pasadena, CA. |
| Sunday, October 2 |
| » Defeated Athletics (52-99), 5-2 | Griffith Stadium (44-32) | 75-75 | |
| » Starters: Jim Reninger vs Joe Krakauskas | Fifth | 23½ out |
| » Lost to Athletics (53-99), 4-2 | Griffith Stadium (44-33) | 75-76 | |
| » Starters: George Caster vs Ken Chase | Fifth | 23½ out |
| Thursday, October 13 |
| Future Senator Ron Moeller is born in Cincinnati, OH. |
| Monday, November 7 |
| Future Senator Jim Kaat is born in Zeeland, MI. |
| Sunday, December 4 |
| Future Senator Billy Bryan is born in Morgan, GA. |
Game information provided by Retrosheet (www.retrosheet.org) |