| Monday, January 31 |
| Former Red Sox Charlie Chech dies in Los Angeles, CA at the age of 60. |
| Saturday, February 19 |
| Future Red Sox Bob Sadowski is born in Pittsburgh, PA. |
| Friday, March 18 |
| Former Red Sox Hobe Ferris dies in Detroit, MI at the age of 61. |
| Sunday, March 20 |
| Former Red Sox Bob Fothergill dies in Detroit, MI at the age of 41. |
| Monday, April 18 |
| » Defeated Yankees (0-1), 8-4 | Fenway Park (1-0) | 1-0 | |
| » Starters: Red Ruffing vs Jim Bagby | First | -- |
| » Major-league debuts: Jim Bagby Jr. (Red Sox) Joe Gordon (Yankees) |
| Tuesday, April 19 |
| » Lost to Yankees (1-1), 5-3 | Fenway Park (1-1) | 1-1 | |
| » Starters: Lefty Gomez vs Lefty Grove | Third | ½ out |
| » Defeated Yankees (1-2), 6-0 | Fenway Park (2-1) | 2-1 | |
| » Starters: Monte Pearson vs Jack Wilson | Third | ½ out |
| » Major-league debuts: Charlie Wagner (Red Sox) Joe Beggs (Yankees) |
| Thursday, April 21 |
| » Defeated Yankees (1-3), 3-2 | Fenway Park (3-1) | 3-1 | Won 2 |
| » Starters: Atley Donald vs Johnny Marcum | Second | ½ out |
| » Major-league debuts: Atley Donald (Yankees) |
| Saturday, April 23 |
| » Defeated Athletics (0-4), 10-4 | Shibe Park (1-0) | 4-1 | Won 3 |
| » Starters: Lefty Grove vs Eddie Smith | First | -- |
| Sunday, April 24 |
| » Lost to Athletics (1-4), 10-4 | Shibe Park (1-1) | 4-2 | |
| » Starters: Emerson Dickman vs George Caster | Second | 1 out |
| Monday, April 25 |
| » Defeated Senators (4-3), 7-0 | Griffith Stadium (1-0) | 5-2 | |
| » Starters: Fritz Ostermueller vs Dutch Leonard | Second | ½ out |
| Tuesday, April 26 |
| » Lost to Senators (5-3), 6-4 | Griffith Stadium (1-1) | 5-3 | |
| » Starters: Johnny Marcum vs Pete Appleton | Second | 1½ out |
| Wednesday, April 27 |
| » Lost to Senators (6-3), 5-2 | Griffith Stadium (1-2) | 5-4 | Lost 2 |
| » Starters: Archie McKain vs Jimmie DeShong | Third | 1½ out |
| Thursday, April 28 |
| » Defeated Yankees (5-6), 6-1 | Yankee Stadium (1-0) | 6-4 | |
| » Starters: Lefty Grove vs Lefty Gomez | Third | 1½ out |
| Friday, April 29 |
| » Lost to Yankees (6-6), 6-4 | Yankee Stadium (1-1) | 6-5 | |
| » Starters: Fritz Ostermueller vs Atley Donald | Third | 2½ out |
| Sunday, May 1 |
| » Lost to Athletics (4-7), 8-6 | Fenway Park (3-2) | 6-6 | Lost 2 |
| » Starters: Bud Thomas vs Jim Bagby | Third | 3 out |
| Monday, May 2 |
| » Defeated Athletics (4-8), 13-1 | Fenway Park (4-2) | 7-6 | |
| » Starters: Harry Kelley vs Johnny Marcum | Third | 3 out |
| Tuesday, May 3 |
| » Defeated Tigers (5-9), 4-3 | Fenway Park (5-2) | 8-6 | Won 2 |
| » Starters: Roxie Lawson vs Lefty Grove | Second | 3 out |
| Wednesday, May 4 |
| » Lost to Tigers (6-9), 4-1 | Fenway Park (5-3) | 8-7 | |
| » Starters: Boots Poffenberger vs Jack Wilson | Fourth | 3 out |
| Thursday, May 5 |
| » Lost to Tigers (7-9), 7-5 | Fenway Park (5-4) | 8-8 | Lost 2 |
| » Starters: Vern Kennedy vs Fritz Ostermueller | Fifth | 3 out |
| Friday, May 6 |
| » Defeated Browns (5-12), 7-3 | Fenway Park (6-4) | 9-8 | |
| » Starters: Bobo Newsom vs Johnny Marcum | Third | 3 out |
| Saturday, May 7 |
| » Defeated Browns (5-13), 7-2 | Fenway Park (7-4) | 10-8 | Won 2 |
| » Starters: Jim Walkup vs Lefty Grove | Third | 3 out |
| Sunday, May 8 |
| » Defeated Indians (13-6), 5-0 | Fenway Park (8-4) | 11-8 | Won 3 |
| » Starters: Bob Feller vs Jack Wilson | Third | 2 out |
| Monday, May 9 |
| » Defeated Indians (13-7), 15-3 | Fenway Park (9-4) | 12-8 | Won 4 |
| » Starters: Denny Galehouse vs Jim Bagby | Third | 1½ out |
| Wednesday, May 11 |
| » Defeated White Sox (7-11), 4-2 | Fenway Park (10-4) | 13-8 | Won 5 |
| » Starters: Frank Gabler vs Lefty Grove | Third | 1 out |
| Friday, May 13 |
| » Defeated Senators (16-9), 10-0 | Fenway Park (11-4) | 14-8 | Won 6 |
| » Starters: Wes Ferrell vs Jack Wilson | Second | 1½ out |
| Saturday, May 14 |
| » Defeated Senators (16-10), 10-9 | Fenway Park (12-4) | 15-8 | Won 7 |
| » Starters: Dutch Leonard vs Fritz Ostermueller | First | -- |
| Sunday, May 15 |
| » Defeated Senators (16-11), 4-3 | Fenway Park (13-4) | 16-8 | Won 8 |
| » Starters: Monte Weaver vs Lefty Grove | First | -- |
| Thursday, May 19 |
| » Lost to White Sox (9-11), 4-0 | Comiskey Park I (0-1) | 16-9 | |
| » Starters: Jack Wilson vs John Whitehead | Second | 1 out |
| Friday, May 20 |
| » Defeated Browns (7-19), 16-2 | Sportsman's Park III (1-0) | 17-9 | |
| » Starters: Lefty Grove vs Jim Walkup | Second | 1 out |
| Saturday, May 21 |
| » Lost to Browns (8-19), 5-3 | Sportsman's Park III (1-1) | 17-10 | |
| » Starters: Johnny Marcum vs Bobo Newsom | Third | 1 out |
| Sunday, May 22 |
| » Lost to Tigers (13-15), 4-3 | Tiger Stadium (0-1) | 17-11 | Lost 2 |
| » Starters: Jack Wilson vs Boots Poffenberger | Third | 2 out |
| Tuesday, May 24 |
| » Defeated Tigers (13-16), 5-4 | Tiger Stadium (1-1) | 18-11 | |
| » Starters: Lefty Grove vs Elden Auker | Second | 2 out |
| Wednesday, May 25 |
| » Lost to Indians (22-10), 6-4 | League Park II (0-1) | 18-12 | |
| » Starters: Fritz Ostermueller vs Mel Harder | Second | 3 out |
| Thursday, May 26 |
| » Defeated Indians (22-11), 8-4 | League Park II (1-1) | 19-12 | |
| » Starters: Jack Wilson vs Denny Galehouse | Second | 2 out |
| Saturday, May 28 |
| » Lost to Senators (20-17), 3-2 | Griffith Stadium (1-3) | 19-13 | |
| » Starters: Jim Bagby vs Dutch Leonard | Second | 2½ out |
| Sunday, May 29 |
| » Lost to Senators (21-17), 5-3 | Griffith Stadium (1-4) | 19-14 | Lost 2 |
| » Starters: Emerson Dickman vs Wes Ferrell | Second | 2½ out |
| Monday, May 30 |
| » Lost to Yankees (18-14), 10-0 | Yankee Stadium (1-2) | 19-15 | Lost 3 |
| » Starters: Lefty Grove vs Red Ruffing | Fourth | 4½ out |
| » Lost to Yankees (19-14), 5-4 | Yankee Stadium (1-3) | 19-16 | Lost 4 |
| » Starters: Jack Wilson vs Lefty Gomez | Fourth | 4½ out |
| Tuesday, May 31 |
| » Lost to Yankees (20-14), 12-5 | Yankee Stadium (1-4) | 19-17 | Lost 5 |
| » Starters: Johnny Marcum vs Joe Beggs | Fourth | 5 out |
| Wednesday, June 1 |
| » Defeated Browns (11-24), 6-3 | Fenway Park (14-4) | 20-17 | |
| » Starters: Jim Walkup vs Charlie Wagner | Fourth | 4 out |
| Thursday, June 2 |
| » Defeated Browns (11-25), 6-1 | Fenway Park (15-4) | 21-17 | Won 2 |
| » Starters: Oral Hildebrand vs Jim Bagby | Fourth | 4 out |
| Saturday, June 4 |
| » Defeated Tigers (19-22), 5-3 | Fenway Park (16-4) | 22-17 | Won 3 |
| » Starters: Tommy Bridges vs Lefty Grove | Fourth | 4½ out |
| Sunday, June 5 |
| » Lost to Tigers (20-22), 10-4 | Fenway Park (16-5) | 22-18 | |
| » Starters: Vern Kennedy vs Jack Wilson | Fourth | 5½ out |
| Monday, June 6 |
| » Defeated Tigers (20-23), 8-7 | Fenway Park (17-5) | 23-18 | |
| » Starters: Boots Poffenberger vs Charlie Wagner | Fourth | 4½ out |
| Tuesday, June 7 |
| » Lost to Indians (29-14), 7-5 | Fenway Park (17-6) | 23-19 | |
| » Starters: Johnny Allen vs Jim Bagby | Fourth | 5½ out |
| Wednesday, June 8 |
| » Defeated Indians (29-15), 7-6 | Fenway Park (18-6) | 24-19 | |
| » Starters: Bob Feller vs Lee Rogers | Second | 4½ out |
| Thursday, June 9 |
| » Defeated Indians (29-16), 8-0 | Fenway Park (19-6) | 25-19 | Won 2 |
| » Starters: Mel Harder vs Lefty Grove | Second | 3½ out |
| Friday, June 10 |
| » Lost to White Sox (17-24), 15-2 | Fenway Park (19-7) | 25-20 | |
| » Starters: Monty Stratton vs Charlie Wagner | Third | 3½ out |
| » Major-league debuts: Bill Lefebvre (Red Sox) |
| Sunday, June 12 |
| » Defeated White Sox (17-25), 3-2 | Fenway Park (20-7) | 26-20 | |
| » Starters: Ted Lyons vs Jack Wilson | Third | 3 out |
| » Lost to White Sox (18-25), 4-3 | Fenway Park (20-8) | 26-21 | |
| » Starters: Bill Dietrich vs Johnny Marcum | Third | 3 out |
| Tuesday, June 14 |
| » Defeated Browns (15-31), 5-3 | Sportsman's Park III (2-1) | 27-21 | |
| » Starters: Lefty Grove vs Bobo Newsom | Third | 2 out |
| Wednesday, June 15 |
| » Defeated Browns (15-32), 7-4 | Sportsman's Park III (3-1) | 28-21 | Won 2 |
| » Starters: Jim Bagby vs Oral Hildebrand | Third | 2 out |
| Thursday, June 16 |
| » Defeated Browns (15-33), 12-8 | Sportsman's Park III (4-1) | 29-21 | Won 3 |
| » Starters: Charlie Wagner vs Les Tietje | Third | 2 out |
| Friday, June 17 |
| » Defeated White Sox (18-29), 5-1 | Comiskey Park I (1-1) | 30-21 | Won 4 |
| » Starters: Jack Wilson vs Jack Knott | Third | 2 out |
| Saturday, June 18 |
| » Defeated White Sox (18-30), 4-3 | Comiskey Park I (2-1) | 31-21 | Won 5 |
| » Starters: Lefty Grove vs Ted Lyons | Third | 1 out |
| Sunday, June 19 |
| » Lost to White Sox (19-30), 3-2 | Comiskey Park I (2-2) | 31-22 | |
| » Starters: Johnny Marcum vs John Whitehead | Second | 1½ out |
| » Defeated White Sox (19-31), 6-1 | Comiskey Park I (3-2) | 32-22 | |
| » Starters: Jim Bagby vs Bill Dietrich | Second | 1½ out |
| Tuesday, June 21 |
| » Defeated Tigers (28-29), 8-3 | Tiger Stadium (2-1) | 33-22 | Won 2 |
| » Starters: Jack Wilson vs Tommy Bridges | Second | 2 out |
| » Lost to Tigers (29-29), 5-4 | Tiger Stadium (2-2) | 33-23 | |
| » Starters: Charlie Wagner vs Roxie Lawson | Second | 2 out |
| Wednesday, June 22 |
| » Lost to Tigers (30-29), 8-3 | Tiger Stadium (2-3) | 33-24 | Lost 2 |
| » Starters: Lefty Grove vs Vern Kennedy | Second | 3½ out |
| Thursday, June 23 |
| » Lost to Tigers (31-29), 10-2 | Tiger Stadium (2-4) | 33-25 | Lost 3 |
| » Starters: Johnny Marcum vs George Gill | Third | 3½ out |
| Friday, June 24 |
| » Lost to Indians (37-21), 7-6 | League Park II (1-2) | 33-26 | Lost 4 |
| » Starters: Jim Bagby vs Johnny Humphries | Third | 4½ out |
| Monday, June 27 |
| » Lost to Indians (38-21), 7-3 | League Park II (1-3) | 33-27 | Lost 5 |
| » Starters: Lefty Grove vs Bob Feller | Third | 5½ out |
| Wednesday, June 29 |
| » Defeated Senators (34-32), 6-4 | Fenway Park (21-8) | 34-27 | |
| » Starters: Dutch Leonard vs Johnny Marcum | Third | 5 out |
| Thursday, June 30 |
| » Defeated Senators (34-33), 11-1 | Fenway Park (22-8) | 35-27 | Won 2 |
| » Starters: Jimmie DeShong vs Jim Bagby | Third | 5 out |
| Friday, July 1 |
| » Defeated Athletics (26-34), 12-7 | Shibe Park (2-1) | 36-27 | Won 3 |
| » Starters: Lefty Grove vs Bud Thomas | Third | 4½ out |
| Saturday, July 2 |
| » Defeated Athletics (26-35), 6-5 | Shibe Park (3-1) | 37-27 | Won 4 |
| » Starters: Charlie Wagner vs Chubby Dean | Third | 4 out |
| Sunday, July 3 |
| » Lost to Yankees (40-25), 9-3 | Yankee Stadium (1-5) | 37-28 | |
| » Starters: Jack Wilson vs Lefty Gomez | Third | 4½ out |
| Monday, July 4 |
| » Defeated Athletics (27-37), 8-5 | Fenway Park (23-8) | 38-28 | |
| » Starters: Buck Ross vs Fritz Ostermueller | Second | 2½ out |
| » Defeated Athletics (27-38), 5-2 | Fenway Park (24-8) | 39-28 | Won 2 |
| » Starters: Bud Thomas vs Jim Bagby | Second | 2½ out |
| Friday, July 8 |
| » Defeated Yankees (41-26), 9-8 | Fenway Park (25-8) | 40-28 | Won 3 |
| » Starters: Spud Chandler vs Jack Wilson | Third | 2½ out |
| Saturday, July 9 |
| » Lost to Yankees (42-26), 11-6 | Fenway Park (25-9) | 40-29 | |
| » Starters: Monte Pearson vs Jim Bagby | Third | 3½ out |
| Sunday, July 10 |
| » Defeated Yankees (42-27), 6-4 | Fenway Park (26-9) | 41-29 | |
| » Starters: Lefty Gomez vs Lefty Grove | Third | 3½ out |
| Wednesday, July 13 |
| » Defeated Tigers (37-39), 7-4 | Fenway Park (27-9) | 42-29 | Won 2 |
| » Starters: Vern Kennedy vs Emerson Dickman | Third | 3 out |
| » Lost to Tigers (38-39), 9-5 | Fenway Park (27-10) | 42-30 | |
| » Starters: Elden Auker vs Jim Bagby | Third | 3 out |
| Future Red Sox Don Pavletich is born in Milwaukee, WI. |
| Thursday, July 14 |
| » Defeated Tigers (38-40), 12-1 | Fenway Park (28-10) | 43-30 | |
| » Starters: George Gill vs Lefty Grove | Third | 3 out |
| Friday, July 15 |
| » Defeated Browns (22-52), 5-3 | Fenway Park (29-10) | 44-30 | Won 2 |
| » Starters: Lefty Mills vs Johnny Marcum | Third | 3 out |
| Saturday, July 16 |
| » Lost to Browns (23-52), 8-3 | Fenway Park (29-11) | 44-31 | |
| » Starters: Oral Hildebrand vs Dick Midkiff | Third | 4 out |
| Future Red Sox Bob Burda is born in St. Louis, MO. |
| Sunday, July 17 |
| » Defeated Browns (23-53), 11-5 | Fenway Park (30-11) | 45-31 | |
| » Starters: Bobo Newsom vs Emerson Dickman | Third | 3½ out |
| » Defeated Browns (23-54), 14-4 | Fenway Park (31-11) | 46-31 | Won 2 |
| » Starters: Ed Linke vs Jim Bagby | Third | 3½ out |
| Future Red Sox Deron Johnson is born in San Diego, CA. |
| Friday, July 22 |
| » Defeated Indians (48-29), 7-4 | Fenway Park (32-11) | 47-31 | Won 3 |
| » Starters: Bob Feller vs Jack Wilson | Third | 2½ out |
| Monday, July 25 |
| » Defeated Indians (48-30), 4-0 | Fenway Park (33-11) | 48-31 | Won 4 |
| » Starters: Johnny Allen vs Emerson Dickman | Third | 2½ out |
| » Lost to Indians (49-30), 3-0 | Fenway Park (33-12) | 48-32 | |
| » Starters: Mel Harder vs Jim Bagby | Third | 2½ out |
| Tuesday, July 26 |
| » Lost to White Sox (35-39), 9-1 | Comiskey Park I (3-3) | 48-33 | Lost 2 |
| » Starters: Fritz Ostermueller vs Ted Lyons | Third | 4 out |
| Thursday, July 28 |
| » Defeated White Sox (35-40), 13-8 | Comiskey Park I (4-3) | 49-33 | |
| » Starters: Jack Wilson vs Jack Knott | Third | 3 out |
| » Defeated White Sox (35-41), 8-5 | Comiskey Park I (5-3) | 50-33 | Won 2 |
| » Starters: Archie McKain vs John Whitehead | Third | 3 out |
| Saturday, July 30 |
| » Defeated Browns (26-59), 5-4 | Sportsman's Park III (5-1) | 51-33 | Won 3 |
| » Starters: Emerson Dickman vs Bobo Newsom | Third | 3½ out |
| Sunday, July 31 |
| » Lost to Browns (27-59), 7-6 | Sportsman's Park III (5-2) | 51-34 | |
| » Starters: Jim Bagby vs Ed Cole | Third | 5½ out |
| » Lost to Browns (28-59), 10-2 | Sportsman's Park III (5-3) | 51-35 | Lost 2 |
| » Starters: Lee Rogers vs Lefty Mills | Third | 5½ out |
| Tuesday, August 2 |
| » Lost to Indians (54-31), 7-4 | League Park II (1-4) | 51-36 | Lost 3 |
| » Starters: Emerson Dickman vs Denny Galehouse | Third | 5½ out |
| » Major-league debuts: Jim Tabor (Red Sox) |
| Wednesday, August 3 |
| » Defeated Indians (54-32), 4-3 | League Park II (2-4) | 52-36 | |
| » Starters: Jack Wilson vs Mel Harder | Third | 6 out |
| » Lost to Indians (55-32), 8-6 | League Park II (2-5) | 52-37 | |
| » Starters: Bill Harris vs Earl Whitehill | Third | 6 out |
| Friday, August 5 |
| » Defeated Tigers (47-50), 9-8 | Tiger Stadium (3-4) | 53-37 | |
| » Starters: Lefty Grove vs Elden Auker | Third | 6½ out |
| Saturday, August 6 |
| » Defeated Tigers (47-51), 14-8 | Tiger Stadium (4-4) | 54-37 | Won 2 |
| » Starters: Emerson Dickman vs Roxie Lawson | Third | 6½ out |
| Sunday, August 7 |
| » Lost to Tigers (48-51), 7-3 | Tiger Stadium (4-5) | 54-38 | |
| » Starters: Jack Wilson vs George Gill | Third | 7½ out |
| Tuesday, August 9 |
| » Defeated Athletics (34-59), 16-4 | Shibe Park (4-1) | 55-38 | |
| » Starters: Bill Harris vs Nels Potter | Third | 6½ out |
| Wednesday, August 10 |
| » Lost to Athletics (35-59), 5-3 | Shibe Park (4-2) | 55-39 | |
| » Starters: Jim Bagby vs Bud Thomas | Third | 7½ out |
| Thursday, August 11 |
| » Lost to Athletics (36-59), 5-3 | Shibe Park (4-3) | 55-40 | Lost 2 |
| » Starters: Lefty Grove vs George Caster | Third | 8½ out |
| Friday, August 12 |
| » Lost to Senators (53-51), 13-1 | Griffith Stadium (1-5) | 55-41 | Lost 3 |
| » Starters: Jack Wilson vs Dutch Leonard | Third | 9 out |
| Saturday, August 13 |
| » Lost to Senators (54-51), 4-1 | Griffith Stadium (1-6) | 55-42 | Lost 4 |
| » Starters: Fritz Ostermueller vs Monte Weaver | Third | 10 out |
| Sunday, August 14 |
| » Lost to Senators (55-51), 7-1 | Griffith Stadium (1-7) | 55-43 | Lost 5 |
| » Starters: Bill Harris vs Harry Kelley | Third | 11½ out |
| Tuesday, August 16 |
| » Lost to Athletics (38-63), 14-11 | Fenway Park (33-13) | 55-44 | Lost 6 |
| » Starters: Buck Ross vs Jim Bagby | Third | 13 out |
| Wednesday, August 17 |
| » Defeated Athletics (38-64), 4-3 | Fenway Park (34-13) | 56-44 | |
| » Starters: George Caster vs Jack Wilson | Third | 12 out |
| » Defeated Athletics (38-65), 5-0 | Fenway Park (35-13) | 57-44 | Won 2 |
| » Starters: Nels Potter vs Joe Heving | Third | 12 out |
| Thursday, August 18 |
| » Defeated Athletics (38-66), 2-0 | Fenway Park (36-13) | 58-44 | Won 3 |
| » Starters: Bud Thomas vs Jim Bagby | Third | 11½ out |
| Friday, August 19 |
| » Defeated Senators (56-55), 4-3 | Fenway Park (37-13) | 59-44 | Won 4 |
| » Starters: Monte Weaver vs Fritz Ostermueller | Third | 11½ out |
| Saturday, August 20 |
| » Defeated Senators (56-56), 10-7 | Fenway Park (38-13) | 60-44 | Won 5 |
| » Starters: Jimmie DeShong vs Archie McKain | Third | 11½ out |
| Sunday, August 21 |
| » Lost to Senators (57-56), 5-4 | Fenway Park (38-14) | 60-45 | |
| » Starters: Pete Appleton vs Jack Wilson | Third | 12½ out |
| » Defeated Senators (57-57), 7-2 | Fenway Park (39-14) | 61-45 | |
| » Starters: Harry Kelley vs Joe Heving | Third | 12½ out |
| Tuesday, August 23 |
| » Defeated Indians (63-46), 13-3 | Fenway Park (40-14) | 62-45 | Won 2 |
| » Starters: Johnny Humphries vs Fritz Ostermueller | Second | 11½ out |
| » Defeated Indians (63-47), 14-12 | Fenway Park (41-14) | 63-45 | Won 3 |
| » Starters: Denny Galehouse vs Jim Bagby | Second | 11½ out |
| Wednesday, August 24 |
| » Lost to Indians (64-47), 5-3 | Fenway Park (41-15) | 63-46 | |
| » Starters: Mel Harder vs Bill Harris | Second | 12 out |
| Thursday, August 25 |
| » Defeated White Sox (48-61), 1-0 | Fenway Park (42-15) | 64-46 | |
| » Starters: Jack Knott vs Jack Wilson | Second | 12 out |
| » Defeated White Sox (48-62), 9-5 | Fenway Park (43-15) | 65-46 | Won 2 |
| » Starters: John Whitehead vs Joe Heving | Second | 12 out |
| Friday, August 26 |
| » Lost to White Sox (49-62), 12-2 | Fenway Park (43-16) | 65-47 | |
| » Starters: Ted Lyons vs Jim Bagby | Second | 12 out |
| » Defeated White Sox (49-63), 9-8 | Fenway Park (44-16) | 66-47 | |
| » Starters: Johnny Rigney vs Dick Midkiff | Second | 12 out |
| Saturday, August 27 |
| » Defeated White Sox (49-64), 19-6 | Fenway Park (45-16) | 67-47 | Won 2 |
| » Starters: Frank Gabler vs Fritz Ostermueller | Second | 12 out |
| » Defeated White Sox (49-65), 1-0 | Fenway Park (46-16) | 68-47 | Won 3 |
| » Starters: Thornton Lee vs Bill Harris | Second | 12 out |
| Sunday, August 28 |
| » Lost to Tigers (60-59), 4-3 | Fenway Park (46-17) | 68-48 | |
| » Starters: Tommy Bridges vs Emerson Dickman | Second | 13 out |
| Monday, August 29 |
| » Lost to Tigers (61-59), 15-1 | Fenway Park (46-18) | 68-49 | Lost 2 |
| » Starters: Elden Auker vs Jack Wilson | Second | 14 out |
| Tuesday, August 30 |
| » Lost to Browns (44-75), 9-5 | Fenway Park (46-19) | 68-50 | Lost 3 |
| » Starters: Ed Cole vs Joe Heving | Second | 15 out |
| Wednesday, August 31 |
| » Defeated Browns (44-76), 6-3 | Fenway Park (47-19) | 69-50 | |
| » Starters: Lefty Mills vs Bill Harris | Second | 14 out |
| Thursday, September 1 |
| » Defeated Browns (44-77), 5-3 | Fenway Park (48-19) | 70-50 | Won 2 |
| » Starters: Bobo Newsom vs Fritz Ostermueller | Second | 13 out |
| Friday, September 2 |
| » Lost to Yankees (86-39), 6-4 | Yankee Stadium (1-6) | 70-51 | |
| » Starters: Jack Wilson vs Red Ruffing | Second | 14 out |
| Saturday, September 3 |
| » Defeated Yankees (86-40), 9-3 | Yankee Stadium (2-6) | 71-51 | |
| » Starters: Joe Heving vs Lefty Gomez | Second | 13 out |
| Sunday, September 4 |
| » Lost to Athletics (45-81), 12-11 | Shibe Park (4-4) | 71-52 | |
| » Starters: Jim Bagby vs Lynn Nelson | Second | 13½ out |
| » Defeated Athletics (45-82), 12-2 | Shibe Park (5-4) | 72-52 | |
| » Starters: Bill Harris vs Bud Thomas | Second | 13½ out |
| Monday, September 5 |
| » Defeated Senators (63-65), 14-4 | Griffith Stadium (2-7) | 73-52 | Won 2 |
| » Starters: Fritz Ostermueller vs Pete Appleton | Second | 13½ out |
| » Defeated Senators (63-66), 8-6 | Griffith Stadium (3-7) | 74-52 | Won 3 |
| » Starters: Emerson Dickman vs Dutch Leonard | Second | 13½ out |
| Tuesday, September 6 |
| » Lost to Senators (64-66), 7-5 | Griffith Stadium (3-8) | 74-53 | |
| » Starters: Jack Wilson vs Rene Monteagudo | Second | 14 out |
| » Major-league debuts: Rene Monteagudo (Senators) |
| Wednesday, September 7 |
| » Defeated Yankees (89-41), 11-4 | Fenway Park (49-19) | 75-53 | |
| » Starters: Red Ruffing vs Joe Heving | Second | 13 out |
| Thursday, September 8 |
| » Lost to Yankees (90-41), 4-0 | Fenway Park (49-20) | 75-54 | |
| » Starters: Lefty Gomez vs Bill Harris | Second | 14 out |
| Friday, September 9 |
| » Lost to Athletics (47-85), 4-3 | Fenway Park (49-21) | 75-55 | Lost 2 |
| » Starters: Buck Ross vs Jim Bagby | Second | 15 out |
| Saturday, September 10 |
| » Lost to Athletics (48-85), 15-7 | Fenway Park (49-22) | 75-56 | Lost 3 |
| » Starters: Lynn Nelson vs Fritz Ostermueller | Second | 16 out |
| Sunday, September 11 |
| » Defeated Athletics (48-86), 12-7 | Fenway Park (50-22) | 76-56 | |
| » Starters: George Caster vs Joe Heving | Second | 15 out |
| Tuesday, September 13 |
| » Lost to Tigers (71-64), 9-3 | Tiger Stadium (4-6) | 76-57 | |
| » Starters: Bill Harris vs Vern Kennedy | Second | 16 out |
| Future Red Sox Bob Heffner is born in Allentown, PA. |
| Wednesday, September 14 |
| » Defeated Tigers (71-65), 9-2 | Tiger Stadium (5-6) | 77-57 | |
| » Starters: Joe Heving vs Tommy Bridges | Second | 15½ out |
| » Major-league debuts: George Archie and Benny McCoy (Tigers) |
| Thursday, September 15 |
| » Lost to Indians (77-58), 3-2 | League Park II (2-6) | 77-58 | |
| » Starters: Jack Wilson vs Mel Harder | Second | 15 out |
| » Defeated Indians (77-59), 3-2 | League Park II (3-6) | 78-58 | |
| » Starters: Fritz Ostermueller vs Bob Feller | Second | 15 out |
| Friday, September 16 |
| » Defeated Indians (77-60), 2-1 | League Park II (4-6) | 79-58 | Won 2 |
| » Starters: Archie McKain vs Denny Galehouse | Second | 15 out |
| Saturday, September 17 |
| » Lost to Indians (78-60), 5-4 | League Park II (4-7) | 79-59 | |
| » Starters: Jack Wilson vs Earl Whitehill | Second | 15 out |
| Tuesday, September 20 |
| » Defeated Browns (50-87), 12-8 | Sportsman's Park III (6-3) | 80-59 | |
| » Starters: Bill Harris vs Jim Walkup | Second | 12 out |
| » Defeated Browns (50-88), 7-2 | Sportsman's Park III (7-3) | 81-59 | Won 2 |
| » Starters: Joe Heving vs Fred Johnson | Second | 12 out |
| Wednesday, September 21 |
| » Defeated Browns (50-89), 8-4 | Sportsman's Park III (8-3) | 82-59 | Won 3 |
| » Starters: Fritz Ostermueller vs Bobo Newsom | Second | 11 out |
| Saturday, September 24 |
| » Defeated Yankees (95-50), 7-6 | Yankee Stadium (3-6) | 83-59 | Won 4 |
| » Starters: Joe Heving vs Red Ruffing | Second | 10½ out |
| Sunday, September 25 |
| » Defeated Yankees (95-51), 5-3 | Yankee Stadium (4-6) | 84-59 | Won 5 |
| » Starters: Archie McKain vs Bump Hadley | Second | 9½ out |
| » Tied Yankees, 2-2 | Yankee Stadium (4-6) | 84-59 | |
| » Starters: Fritz Ostermueller vs Johnny Murphy | Second | 9½ out |
| Monday, September 26 |
| » Lost to Yankees (96-51), 4-3 | Yankee Stadium (4-7) | 84-60 | |
| » Starters: Jim Bagby vs Steve Sundra | Second | 10½ out |
| Tuesday, September 27 |
| » Defeated Athletics (52-96), 11-1 | Shibe Park (6-4) | 85-60 | |
| » Starters: Bill Harris vs Buck Ross | Second | 10½ out |
| Wednesday, September 28 |
| » Defeated Athletics (52-97), 2-1 | Shibe Park (7-4) | 86-60 | Won 2 |
| » Starters: Joe Heving vs Lynn Nelson | Second | 9½ out |
| Thursday, September 29 |
| » Defeated Senators (74-75), 13-5 | Fenway Park (51-22) | 87-60 | Won 3 |
| » Starters: Pete Appleton vs Fritz Ostermueller | Second | 9½ out |
| Saturday, October 1 |
| » Defeated Yankees (98-53), 9-2 | Fenway Park (52-22) | 88-60 | Won 4 |
| » Starters: Bump Hadley vs Jim Bagby | Second | 8½ out |
| Sunday, October 2 |
| » Lost to Yankees (99-53), 6-1 | Fenway Park (52-23) | 88-61 | |
| » Starters: Lefty Gomez vs Emerson Dickman | Second | 9½ out |
| Monday, November 14 |
| Former Red Sox Les Nunamaker dies in Hastings, NE at the age of 50. |
| Sunday, November 27 |
| Future Red Sox Jose Tartabull is born in Cienfuegos, Cuba. |
Game information provided by Retrosheet (www.retrosheet.org) |
