| Friday, January 15 |
| Former Yankee Eddie Foster dies in Washington, DC at the age of 50. |
| Thursday, February 4 |
| Former Yankee Harry Wolverton dies in Oakland, CA at the age of 64. |
| Tuesday, February 9 |
| Future Yankee Clete Boyer is born in Cassville, MO. |
| Wednesday, March 24 |
| Future Yankee Bob Tillman is born in Nashville, TN. |
| Tuesday, April 20 |
| » Lost to Senators (1-1), 3-2 | Yankee Stadium (0-1) | 0-1 | |
| » Starters: Monte Weaver vs Lefty Gomez | Fourth | 1 out |
| Friday, April 23 |
| » Major-league debuts: Ben Huffman and Bill Trotter (Browns) |
| Future Yankee Duke Carmel is born in New York, NY. |
| Saturday, April 24 |
| » Defeated Red Sox (1-1), 6-5 | Fenway Park (1-0) | 1-1 | |
| » Starters: Monte Pearson vs Lefty Grove | Third | 1 out |
| Sunday, April 25 |
| » Defeated Red Sox (1-2), 9-3 | Fenway Park (2-0) | 2-1 | Won 2 |
| » Starters: Bump Hadley vs Wes Ferrell | Second | ½ out |
| » Major-league debuts: Archie McKain (Red Sox) |
| Monday, April 26 |
| » Defeated Athletics (3-2), 7-1 | Yankee Stadium (1-1) | 3-1 | Won 3 |
| » Starters: Harry Kelley vs Johnny Broaca | First | -- |
| Wednesday, April 28 |
| » Defeated Senators (1-5), 6-1 | Griffith Stadium (1-0) | 4-1 | Won 4 |
| » Starters: Lefty Gomez vs Joe Cascarella | First | -- |
| Thursday, April 29 |
| » Defeated Senators (1-6), 4-2 | Griffith Stadium (2-0) | 5-1 | Won 5 |
| » Starters: Monte Pearson vs Monte Weaver | First | -- |
| Friday, April 30 |
| » Lost to Senators (2-6), 4-1 | Griffith Stadium (2-1) | 5-2 | |
| » Starters: Kemp Wicker vs Bobo Newsom | First | -- |
| Saturday, May 1 |
| » Defeated Red Sox (3-3), 3-2 | Yankee Stadium (2-1) | 6-2 | |
| » Starters: Rube Walberg vs Bump Hadley | First | -- |
| Sunday, May 2 |
| » Lost to Red Sox (4-3), 5-4 | Yankee Stadium (2-2) | 6-3 | |
| » Starters: Johnny Marcum vs Johnny Broaca | Second | ½ out |
| Tuesday, May 4 |
| » Defeated Tigers (7-3), 10-1 | Tiger Stadium (1-0) | 7-3 | |
| » Starters: Lefty Gomez vs Jake Wade | First | -- |
| » Major-league debuts: George Gill (Tigers) |
| Wednesday, May 5 |
| » Defeated Tigers (7-4), 7-3 | Tiger Stadium (2-0) | 8-3 | Won 2 |
| » Starters: Monte Pearson vs Vic Sorrell | First | -- |
| » Major-league debuts: Chet Laabs (Tigers) |
| Thursday, May 6 |
| » Lost to Tigers (8-4), 12-6 | Tiger Stadium (2-1) | 8-4 | |
| » Starters: Johnny Murphy vs Tommy Bridges | First | -- |
| » Major-league debuts: Spud Chandler (Yankees) |
| Friday, May 7 |
| » Lost to Indians (6-5), 7-6 | League Park II (0-1) | 8-5 | Lost 2 |
| » Starters: Bump Hadley vs Denny Galehouse | Third | 1½ out |
| Saturday, May 8 |
| » Lost to Indians (7-5), 4-0 | League Park II (0-2) | 8-6 | Lost 3 |
| » Starters: Lefty Gomez vs Ivy Andrews | Fourth | 1 out |
| Sunday, May 9 |
| » Lost to White Sox (5-9), 2-1 | Comiskey Park I (0-1) | 8-7 | Lost 4 |
| » Starters: Spud Chandler vs Thornton Lee | Fourth | 1 out |
| Monday, May 10 |
| » Defeated White Sox (5-10), 7-0 | Comiskey Park I (1-1) | 9-7 | |
| » Starters: Monte Pearson vs Ted Lyons | Second | 1 out |
| Tuesday, May 11 |
| » Lost to White Sox (6-10), 7-2 | Comiskey Park I (1-2) | 9-8 | |
| » Starters: Bump Hadley vs Monty Stratton | Fourth | 2 out |
| Thursday, May 13 |
| » Defeated Browns (6-10), 4-2 | Sportsman's Park III (1-0) | 10-8 | |
| » Starters: Lefty Gomez vs Jim Walkup | Third | 1½ out |
| Saturday, May 15 |
| » Defeated Athletics (10-6), 6-5 | Shibe Park (1-0) | 11-8 | Won 2 |
| » Starters: Monte Pearson vs Harry Kelley | Second | 1½ out |
| Sunday, May 16 |
| » Defeated Athletics (10-7), 8-4 | Shibe Park (2-0) | 12-8 | Won 3 |
| » Starters: Red Ruffing vs George Caster | First | -- |
| Monday, May 17 |
| » Lost to Athletics (11-7), 3-2 | Shibe Park (2-1) | 12-9 | |
| » Starters: Lefty Gomez vs Bud Thomas | Second | 1½ out |
| Tuesday, May 18 |
| » Defeated White Sox (9-12), 4-0 | Yankee Stadium (3-2) | 13-9 | |
| » Starters: Ted Lyons vs Spud Chandler | Second | 1½ out |
| Thursday, May 20 |
| » Lost to White Sox (10-12), 3-1 | Yankee Stadium (3-3) | 13-10 | |
| » Starters: Thornton Lee vs Johnny Broaca | Third | 2 out |
| Friday, May 21 |
| » Defeated Browns (8-15), 4-3 | Yankee Stadium (4-3) | 14-10 | |
| » Starters: Chief Hogsett vs Monte Pearson | Third | 2 out |
| Saturday, May 22 |
| » Defeated Browns (8-16), 14-2 | Yankee Stadium (5-3) | 15-10 | Won 2 |
| » Starters: Julio Bonetti vs Lefty Gomez | Second | 1 out |
| Sunday, May 23 |
| » Defeated Indians (12-10), 7-3 | Yankee Stadium (6-3) | 16-10 | Won 3 |
| » Starters: Denny Galehouse vs Red Ruffing | Second | 1 out |
| Monday, May 24 |
| » Defeated Indians (12-11), 14-0 | Yankee Stadium (7-3) | 17-10 | Won 4 |
| » Starters: Ivy Andrews vs Spud Chandler | First | -- |
| Tuesday, May 25 |
| » Defeated Tigers (16-13), 4-3 | Yankee Stadium (8-3) | 18-10 | Won 5 |
| » Starters: Schoolboy Rowe vs Bump Hadley | First | -- |
| Wednesday, May 26 |
| » Defeated Tigers (16-14), 7-0 | Yankee Stadium (9-3) | 19-10 | Won 6 |
| » Starters: Slick Coffman vs Lefty Gomez | First | -- |
| Thursday, May 27 |
| » Lost to Tigers (17-14), 5-4 | Yankee Stadium (9-4) | 19-11 | |
| » Starters: Tommy Bridges vs Johnny Broaca | First | -- |
| Saturday, May 29 |
| » Defeated Athletics (15-14), 9-4 | Yankee Stadium (10-4) | 20-11 | |
| » Starters: Buck Ross vs Red Ruffing | First | -- |
| » Defeated Athletics (15-15), 10-3 | Yankee Stadium (11-4) | 21-11 | Won 2 |
| » Starters: Eddie Smith vs Spud Chandler | First | -- |
| Sunday, May 30 |
| » Defeated Athletics (15-16), 13-1 | Yankee Stadium (12-4) | 22-11 | Won 3 |
| » Starters: Harry Kelley vs Lefty Gomez | First | -- |
| Monday, May 31 |
| » Defeated Red Sox (15-15), 4-3 | Fenway Park (3-0) | 23-11 | Won 4 |
| » Starters: Bump Hadley vs Lefty Grove | First | -- |
| » Lost to Red Sox (16-15), 8-2 | Fenway Park (3-1) | 23-12 | |
| » Starters: Johnny Broaca vs Rube Walberg | First | -- |
| Wednesday, June 2 |
| » Defeated Indians (19-15), 8-4 | League Park II (1-2) | 24-12 | |
| » Starters: Red Ruffing vs Earl Whitehill | First | -- |
| Thursday, June 3 |
| » Lost to Indians (20-15), 6-2 | League Park II (1-3) | 24-13 | |
| » Starters: Lefty Gomez vs Mel Harder | First | -- |
| Friday, June 4 |
| » Lost to Indians (21-15), 5-3 | League Park II (1-4) | 24-14 | Lost 2 |
| » Starters: Spud Chandler vs Johnny Allen | First | -- |
| Saturday, June 5 |
| » Defeated Tigers (22-20), 6-5 | Tiger Stadium (3-1) | 25-14 | |
| » Starters: Bump Hadley vs George Gill | First | -- |
| Sunday, June 6 |
| » Lost to Tigers (23-20), 5-4 | Tiger Stadium (3-2) | 25-15 | |
| » Starters: Red Ruffing vs Roxie Lawson | First | -- |
| Monday, June 7 |
| » Lost to Tigers (24-20), 4-3 | Tiger Stadium (3-3) | 25-16 | Lost 2 |
| » Starters: Lefty Gomez vs Jake Wade | First | -- |
| Tuesday, June 8 |
| » Lost to White Sox (25-17), 5-4 | Comiskey Park I (1-3) | 25-17 | Lost 3 |
| » Starters: Johnny Broaca vs Thornton Lee | First | -- |
| Thursday, June 10 |
| » Defeated White Sox (25-18), 10-3 | Comiskey Park I (2-3) | 26-17 | |
| » Starters: Bump Hadley vs Vern Kennedy | First | -- |
| Friday, June 11 |
| » Defeated Browns (14-29), 10-0 | Sportsman's Park III (2-0) | 27-17 | Won 2 |
| » Starters: Red Ruffing vs Jack Knott | First | -- |
| Saturday, June 12 |
| » Lost to Browns (15-29), 7-6 | Sportsman's Park III (2-1) | 27-18 | |
| » Starters: Lefty Gomez vs Chief Hogsett | First | -- |
| Sunday, June 13 |
| » Defeated Browns (15-30), 16-9 | Sportsman's Park III (3-1) | 28-18 | |
| » Starters: Johnny Murphy vs Oral Hildebrand | First | -- |
| » Tied Browns, 8-8 | Sportsman's Park III (3-1) | 28-18 | |
| » Starters: Bump Hadley vs Julio Bonetti | First | -- |
| Tuesday, June 15 |
| » Defeated Indians (26-20), 3-0 | Yankee Stadium (13-4) | 29-18 | Won 2 |
| » Starters: Mel Harder vs Red Ruffing | First | -- |
| Wednesday, June 16 |
| » Defeated Indians (26-21), 4-1 | Yankee Stadium (14-4) | 30-18 | Won 3 |
| » Starters: Denny Galehouse vs Lefty Gomez | First | -- |
| Thursday, June 17 |
| » Defeated Indians (26-22), 9-7 | Yankee Stadium (15-4) | 31-18 | Won 4 |
| » Starters: Earl Whitehill vs Bump Hadley | First | -- |
| Saturday, June 19 |
| » Lost to White Sox (29-23), 5-2 | Yankee Stadium (15-5) | 31-19 | |
| » Starters: Thornton Lee vs Red Ruffing | First | -- |
| Sunday, June 20 |
| » Defeated White Sox (29-24), 8-4 | Yankee Stadium (16-5) | 32-19 | |
| » Starters: Ted Lyons vs Lefty Gomez | First | -- |
| » Defeated White Sox (29-25), 7-4 | Yankee Stadium (17-5) | 33-19 | Won 2 |
| » Starters: John Whitehead vs Monte Pearson | First | -- |
| Tuesday, June 22 |
| » Defeated Browns (18-33), 8-5 | Yankee Stadium (18-5) | 34-19 | Won 3 |
| » Starters: Jack Knott vs Pat Malone | First | -- |
| Wednesday, June 23 |
| » Lost to Browns (19-33), 6-3 | Yankee Stadium (18-6) | 34-20 | |
| » Starters: Oral Hildebrand vs Spud Chandler | First | -- |
| Thursday, June 24 |
| » Defeated Browns (19-34), 9-6 | Yankee Stadium (19-6) | 35-20 | |
| » Starters: Chief Hogsett vs Bump Hadley | First | -- |
| Friday, June 25 |
| » Defeated Tigers (33-25), 8-1 | Yankee Stadium (20-6) | 36-20 | Won 2 |
| » Starters: Tommy Bridges vs Red Ruffing | First | -- |
| Saturday, June 26 |
| » Lost to Tigers (34-25), 5-3 | Yankee Stadium (20-7) | 36-21 | |
| » Starters: Jake Wade vs Lefty Gomez | First | -- |
| Sunday, June 27 |
| » Defeated Tigers (34-26), 9-5 | Yankee Stadium (21-7) | 37-21 | |
| » Starters: Roxie Lawson vs Pat Malone | First | -- |
| Tuesday, June 29 |
| » Defeated Athletics (20-37), 3-2 | Shibe Park (3-1) | 38-21 | Won 2 |
| » Starters: Spud Chandler vs Eddie Smith | First | -- |
| Wednesday, June 30 |
| » Defeated Athletics (20-38), 5-1 | Shibe Park (4-1) | 39-21 | Won 3 |
| » Starters: Lefty Gomez vs Bud Thomas | First | -- |
| Thursday, July 1 |
| » Defeated Athletics (20-39), 12-7 | Shibe Park (5-1) | 40-21 | Won 4 |
| » Starters: Red Ruffing vs Buck Ross | First | -- |
| Friday, July 2 |
| » Lost to Senators (29-33), 8-3 | Griffith Stadium (2-2) | 40-22 | |
| » Starters: Bump Hadley vs Carl Fischer | First | -- |
| Former Yankee Joe Yeager dies in Detroit, MI at the age of 62. |
| Saturday, July 3 |
| » Defeated Senators (29-34), 5-4 | Griffith Stadium (3-2) | 41-22 | |
| » Starters: Johnny Murphy vs Monte Weaver | First | -- |
| Sunday, July 4 |
| » Defeated Senators (29-35), 7-0 | Griffith Stadium (4-2) | 42-22 | Won 2 |
| » Starters: Lefty Gomez vs Wes Ferrell | First | -- |
| Monday, July 5 |
| » Defeated Red Sox (35-27), 15-0 | Yankee Stadium (22-7) | 43-22 | Won 3 |
| » Starters: Jack Wilson vs Red Ruffing | First | -- |
| » Defeated Red Sox (35-28), 8-4 | Yankee Stadium (23-7) | 44-22 | Won 4 |
| » Starters: Rube Walberg vs Spud Chandler | First | -- |
| Friday, July 9 |
| » Defeated Senators (30-36), 16-2 | Yankee Stadium (24-7) | 45-22 | Won 5 |
| » Starters: Carl Fischer vs Monte Pearson | First | -- |
| Saturday, July 10 |
| » Defeated Senators (30-37), 12-2 | Yankee Stadium (25-7) | 46-22 | Won 6 |
| » Starters: Wes Ferrell vs Red Ruffing | First | -- |
| Sunday, July 11 |
| » Defeated Senators (30-38), 4-3 | Yankee Stadium (26-7) | 47-22 | Won 7 |
| » Starters: Monte Weaver vs Lefty Gomez | First | -- |
| » Tied Senators, 5-5 | Yankee Stadium (26-7) | 47-22 | |
| » Starters: Jimmie DeShong vs Johnny Murphy | First | -- |
| Wednesday, July 14 |
| » Defeated Tigers (42-30), 10-2 | Tiger Stadium (4-3) | 48-22 | Won 8 |
| » Starters: Red Ruffing vs Jake Wade | First | -- |
| Thursday, July 15 |
| » Defeated Tigers (42-31), 13-6 | Tiger Stadium (5-3) | 49-22 | Won 9 |
| » Starters: Lefty Gomez vs Schoolboy Rowe | First | -- |
| Friday, July 16 |
| » Lost to Tigers (43-31), 14-7 | Tiger Stadium (5-4) | 49-23 | |
| » Starters: Monte Pearson vs Boots Poffenberger | First | -- |
| Saturday, July 17 |
| » Defeated Indians (37-35), 9-6 | League Park II (2-4) | 50-23 | |
| » Starters: Bump Hadley vs Denny Galehouse | First | -- |
| Sunday, July 18 |
| » Defeated Indians (37-36), 5-1 | Cleveland Stadium (1-0) | 51-23 | Won 2 |
| » Starters: Red Ruffing vs Bob Feller | First | -- |
| Former Yankee Fred Jacklitsch dies in Brooklyn, NY at the age of 62. |
| Monday, July 19 |
| » Defeated Indians (37-37), 8-5 | League Park II (3-4) | 52-23 | Won 3 |
| » Starters: Lefty Gomez vs Willis Hudlin | First | -- |
| Tuesday, July 20 |
| » Defeated Browns (25-51), 5-4 | Sportsman's Park III (4-1) | 53-23 | Won 4 |
| » Starters: Monte Pearson vs Oral Hildebrand | First | -- |
| » Defeated Browns (25-52), 9-6 | Sportsman's Park III (5-1) | 54-23 | Won 5 |
| » Starters: Pat Malone vs Chief Hogsett | First | -- |
| Wednesday, July 21 |
| » Defeated Browns (25-53), 6-3 | Sportsman's Park III (6-1) | 55-23 | Won 6 |
| » Starters: Kemp Wicker vs Lou Koupal | First | -- |
| Thursday, July 22 |
| » Lost to Browns (26-53), 13-4 | Sportsman's Park III (6-2) | 55-24 | |
| » Starters: Bump Hadley vs Jack Knott | First | -- |
| Friday, July 23 |
| » Lost to White Sox (51-33), 9-6 | Comiskey Park I (2-4) | 55-25 | Lost 2 |
| » Starters: Red Ruffing vs John Whitehead | First | -- |
| Saturday, July 24 |
| » Lost to White Sox (52-33), 6-5 | Comiskey Park I (2-5) | 55-26 | Lost 3 |
| » Starters: Lefty Gomez vs Thornton Lee | First | -- |
| Sunday, July 25 |
| » Defeated White Sox (52-34), 12-11 | Comiskey Park I (3-5) | 56-26 | |
| » Starters: Bump Hadley vs Ted Lyons | First | -- |
| » Lost to White Sox (53-34), 7-6 | Comiskey Park I (3-6) | 56-27 | |
| » Starters: Pat Malone vs Monty Stratton | First | -- |
| Tuesday, July 27 |
| » Defeated Tigers (50-34), 6-5 | Yankee Stadium (27-7) | 57-27 | |
| » Starters: Jake Wade vs Red Ruffing | First | -- |
| Wednesday, July 28 |
| » Lost to Tigers (51-34), 8-1 | Yankee Stadium (27-8) | 57-28 | |
| » Starters: Elden Auker vs Lefty Gomez | First | -- |
| Thursday, July 29 |
| » Defeated Tigers (51-35), 7-6 | Yankee Stadium (28-8) | 58-28 | |
| » Starters: Boots Poffenberger vs Monte Pearson | First | -- |
| Friday, July 30 |
| » Defeated Browns (28-60), 8-2 | Yankee Stadium (29-8) | 59-28 | Won 2 |
| » Starters: Chief Hogsett vs Kemp Wicker | First | -- |
| Saturday, July 31 |
| » Lost to Browns (29-60), 9-6 | Yankee Stadium (29-9) | 59-29 | |
| » Starters: Jack Knott vs Pat Malone | First | -- |
| Sunday, August 1 |
| » Defeated Browns (29-61), 14-5 | Yankee Stadium (30-9) | 60-29 | |
| » Starters: Lou Koupal vs Spud Chandler | First | -- |
| Tuesday, August 3 |
| » Defeated White Sox (57-37), 7-2 | Yankee Stadium (31-9) | 61-29 | Won 2 |
| » Starters: Thornton Lee vs Red Ruffing | First | -- |
| » Defeated White Sox (57-38), 5-3 | Yankee Stadium (32-9) | 62-29 | Won 3 |
| » Starters: John Whitehead vs Lefty Gomez | First | -- |
| Wednesday, August 4 |
| » Defeated White Sox (57-39), 10-9 | Yankee Stadium (33-9) | 63-29 | Won 4 |
| » Starters: Vern Kennedy vs Monte Pearson | First | -- |
| Thursday, August 5 |
| » Defeated White Sox (57-40), 13-8 | Yankee Stadium (34-9) | 64-29 | Won 5 |
| » Starters: Monty Stratton vs Kemp Wicker | First | -- |
| Friday, August 6 |
| » Defeated Indians (43-49), 7-6 | Yankee Stadium (35-9) | 65-29 | Won 6 |
| » Starters: Bob Feller vs Bump Hadley | First | -- |
| Saturday, August 7 |
| » Defeated Indians (43-50), 6-3 | Yankee Stadium (36-9) | 66-29 | Won 7 |
| » Starters: Mel Harder vs Red Ruffing | First | -- |
| Sunday, August 8 |
| » Defeated Indians (43-51), 6-5 | Yankee Stadium (37-9) | 67-29 | Won 8 |
| » Starters: Earl Whitehill vs Spud Chandler | First | -- |
| Wednesday, August 11 |
| » Defeated Red Sox (57-39), 8-5 | Fenway Park (4-1) | 68-29 | Won 9 |
| » Starters: Red Ruffing vs Lefty Grove | First | -- |
| » Defeated Red Sox (57-40), 10-4 | Fenway Park (5-1) | 69-29 | Won 10 |
| » Starters: Pat Malone vs Bobo Newsom | First | -- |
| Thursday, August 12 |
| » Lost to Red Sox (58-40), 16-10 | Fenway Park (5-2) | 69-30 | |
| » Starters: Monte Pearson vs Johnny Marcum | First | -- |
| » Defeated Red Sox (58-41), 5-3 | Fenway Park (6-2) | 70-30 | |
| » Starters: Bump Hadley vs Archie McKain | First | -- |
| Friday, August 13 |
| » Lost to Athletics (30-69), 4-3 | Shibe Park (5-2) | 70-31 | |
| » Starters: Lefty Gomez vs Buck Ross | First | -- |
| Saturday, August 14 |
| » Lost to Athletics (31-69), 12-6 | Shibe Park (5-3) | 70-32 | Lost 2 |
| » Starters: Kemp Wicker vs Bud Thomas | First | -- |
| Sunday, August 15 |
| » Lost to Athletics (32-69), 5-4 | Shibe Park (5-4) | 70-33 | Lost 3 |
| » Starters: Red Ruffing vs Eddie Smith | First | -- |
| Tuesday, August 17 |
| » Defeated Senators (49-54), 8-0 | Yankee Stadium (38-9) | 71-33 | |
| » Starters: Pete Appleton vs Lefty Gomez | First | -- |
| » Defeated Senators (49-55), 6-4 | Yankee Stadium (39-9) | 72-33 | Won 2 |
| » Starters: Jimmie DeShong vs Bump Hadley | First | -- |
| Wednesday, August 18 |
| » Defeated Senators (49-56), 7-6 | Yankee Stadium (40-9) | 73-33 | Won 3 |
| » Starters: Ed Linke vs Pat Malone | First | -- |
| Thursday, August 19 |
| » Defeated Senators (49-57), 4-3 | Yankee Stadium (41-9) | 74-33 | Won 4 |
| » Starters: Wes Ferrell vs Red Ruffing | First | -- |
| Friday, August 20 |
| » Defeated Athletics (33-72), 8-7 | Yankee Stadium (42-9) | 75-33 | Won 5 |
| » Starters: Buck Ross vs Ivy Andrews | First | -- |
| Saturday, August 21 |
| » Lost to Athletics (34-72), 5-2 | Yankee Stadium (42-10) | 75-34 | |
| » Starters: Eddie Smith vs Monte Pearson | First | -- |
| Sunday, August 22 |
| » Defeated Athletics (34-73), 4-1 | Yankee Stadium (43-10) | 76-34 | |
| » Starters: Bud Thomas vs Lefty Gomez | First | -- |
| Tuesday, August 24 |
| » Lost to White Sox (65-50), 9-8 | Comiskey Park I (3-7) | 76-35 | |
| » Starters: Red Ruffing vs John Whitehead | First | -- |
| Wednesday, August 25 |
| » Defeated White Sox (65-51), 10-5 | Comiskey Park I (4-7) | 77-35 | |
| » Starters: Bump Hadley vs Thornton Lee | First | -- |
| Thursday, August 26 |
| » Defeated Browns (35-78), 5-1 | Sportsman's Park III (7-2) | 78-35 | Won 2 |
| » Starters: Lefty Gomez vs Jack Knott | First | -- |
| Friday, August 27 |
| » Defeated Browns (35-79), 4-3 | Sportsman's Park III (8-2) | 79-35 | Won 3 |
| » Starters: Red Ruffing vs Oral Hildebrand | First | -- |
| Saturday, August 28 |
| » Lost to Browns (36-79), 9-5 | Sportsman's Park III (8-3) | 79-36 | |
| » Starters: Pat Malone vs Jim Walkup | First | -- |
| Sunday, August 29 |
| » Defeated Tigers (68-49), 7-4 | Tiger Stadium (6-4) | 80-36 | |
| » Starters: Red Ruffing vs Tommy Bridges | First | -- |
| Monday, August 30 |
| » Lost to Tigers (69-49), 5-4 | Tiger Stadium (6-5) | 80-37 | |
| » Starters: Lefty Gomez vs Elden Auker | First | -- |
| Tuesday, August 31 |
| » Defeated Indians (59-58), 7-3 | League Park II (4-4) | 81-37 | |
| » Starters: Bump Hadley vs Mel Harder | First | -- |
| Wednesday, September 1 |
| » Lost to Indians (60-58), 4-2 | League Park II (4-5) | 81-38 | |
| » Starters: Kemp Wicker vs Denny Galehouse | First | -- |
| Thursday, September 2 |
| » Lost to Indians (61-58), 4-2 | League Park II (4-6) | 81-39 | Lost 2 |
| » Starters: Monte Pearson vs Bob Feller | First | -- |
| Friday, September 3 |
| » Lost to Senators (56-63), 4-2 | Griffith Stadium (4-3) | 81-40 | Lost 3 |
| » Starters: Red Ruffing vs Ken Chase | First | -- |
| » Major-league debuts: Jimmy Wasdell (Senators) |
| Saturday, September 4 |
| » Defeated Senators (56-64), 6-0 | Griffith Stadium (5-3) | 82-40 | |
| » Starters: Lefty Gomez vs Pete Appleton | First | -- |
| Sunday, September 5 |
| » Defeated Senators (56-65), 10-5 | Griffith Stadium (6-3) | 83-40 | Won 2 |
| » Starters: Kemp Wicker vs Dick Lanahan | First | -- |
| Monday, September 6 |
| » Defeated Athletics (40-82), 6-3 | Shibe Park (6-4) | 84-40 | Won 3 |
| » Starters: Bump Hadley vs Buck Ross | First | -- |
| » Defeated Athletics (40-83), 2-1 | Shibe Park (7-4) | 85-40 | Won 4 |
| » Starters: Ivy Andrews vs Eddie Smith | First | -- |
| Wednesday, September 8 |
| » Defeated Red Sox (67-59), 3-2 | Yankee Stadium (44-10) | 86-40 | Won 5 |
| » Starters: Bobo Newsom vs Red Ruffing | First | -- |
| » Defeated Red Sox (67-60), 9-6 | Yankee Stadium (45-10) | 87-40 | Won 6 |
| » Starters: Jack Wilson vs Monte Pearson | First | -- |
| Thursday, September 9 |
| » Lost to Red Sox (68-60), 13-7 | Yankee Stadium (45-11) | 87-41 | |
| » Starters: Archie McKain vs Pat Malone | First | -- |
| Friday, September 10 |
| » Lost to Red Sox (69-60), 4-3 | Yankee Stadium (45-12) | 87-42 | Lost 2 |
| » Starters: Lefty Grove vs Ivy Andrews | First | -- |
| Saturday, September 11 |
| » Defeated Senators (62-69), 6-4 | Yankee Stadium (46-12) | 88-42 | |
| » Starters: Jimmie DeShong vs Kemp Wicker | First | -- |
| Sunday, September 12 |
| » Lost to Senators (63-69), 2-1 | Yankee Stadium (46-13) | 88-43 | |
| » Starters: Ken Chase vs Red Ruffing | First | -- |
| » Defeated Senators (63-70), 2-1 | Yankee Stadium (47-13) | 89-43 | |
| » Starters: Bill Phebus vs Lefty Gomez | First | -- |
| Tuesday, September 14 |
| » Defeated Indians (71-63), 17-5 | Yankee Stadium (48-13) | 90-43 | Won 2 |
| » Starters: Earl Whitehill vs Bump Hadley | First | -- |
| Wednesday, September 15 |
| » Lost to Indians (72-63), 5-4 | Yankee Stadium (48-14) | 90-44 | |
| » Starters: Bob Feller vs Joe Vance | First | -- |
| » Defeated Indians (72-64), 3-1 | Yankee Stadium (49-14) | 91-44 | |
| » Starters: Denny Galehouse vs Monte Pearson | First | -- |
| Future Yankee Charley Smith is born in Charleston, SC. |
| Thursday, September 16 |
| » Defeated Indians (72-65), 8-0 | Yankee Stadium (50-14) | 92-44 | Won 2 |
| » Starters: Willis Hudlin vs Lefty Gomez | First | -- |
| Saturday, September 18 |
| » Defeated White Sox (77-60), 12-8 | Yankee Stadium (51-14) | 93-44 | Won 3 |
| » Starters: Thornton Lee vs Red Ruffing | First | -- |
| » Defeated White Sox (77-61), 4-0 | Yankee Stadium (52-14) | 94-44 | Won 4 |
| » Starters: John Whitehead vs Ivy Andrews | First | -- |
| Sunday, September 19 |
| » Lost to Tigers (83-56), 8-1 | Yankee Stadium (52-15) | 94-45 | |
| » Starters: Elden Auker vs Bump Hadley | First | -- |
| Monday, September 20 |
| » Defeated Tigers (83-57), 5-0 | Yankee Stadium (53-15) | 95-45 | |
| » Starters: Jake Wade vs Lefty Gomez | First | -- |
| Future Yankee Tom Tresh is born in Detroit, MI. |
| Wednesday, September 22 |
| » Defeated Browns (42-100), 4-1 | Yankee Stadium (54-15) | 96-45 | Won 2 |
| » Starters: Jack Knott vs Monte Pearson | First | -- |
| » Defeated Browns (42-101), 11-0 | Yankee Stadium (55-15) | 97-45 | Won 3 |
| » Starters: Chief Hogsett vs Kemp Wicker | First | -- |
| Thursday, September 23 |
| » Lost to Browns (43-101), 9-5 | Yankee Stadium (55-16) | 97-46 | |
| » Starters: Bill Trotter vs Red Ruffing | First | -- |
| Friday, September 24 |
| » Defeated Red Sox (74-67), 5-1 | Fenway Park (7-2) | 98-46 | |
| » Starters: Joe Vance vs Archie McKain | First | -- |
| Saturday, September 25 |
| » Defeated Red Sox (74-68), 5-2 | Fenway Park (8-2) | 99-46 | Won 2 |
| » Starters: Lefty Gomez vs Lefty Grove | First | -- |
| Sunday, September 26 |
| » Lost to Red Sox (75-68), 7-2 | Fenway Park (8-3) | 99-47 | |
| » Starters: Bump Hadley vs Jack Wilson | First | -- |
| Tuesday, September 28 |
| » Defeated Senators (70-75), 9-0 | Griffith Stadium (7-3) | 100-47 | |
| » Starters: Red Ruffing vs Monte Weaver | First | -- |
| » Lost to Senators (71-75), 2-1 | Griffith Stadium (7-4) | 100-48 | |
| » Starters: Monte Pearson vs Joe Krakauskas | First | -- |
| Wednesday, September 29 |
| » Defeated Athletics (49-96), 15-4 | Yankee Stadium (56-16) | 101-48 | |
| » Starters: George Caster vs Kemp Wicker | First | -- |
| » Lost to Athletics (50-96), 3-0 | Yankee Stadium (56-17) | 101-49 | |
| » Starters: Eddie Smith vs Ivy Andrews | First | -- |
| Thursday, September 30 |
| » Lost to Athletics (51-96), 8-3 | Yankee Stadium (56-18) | 101-50 | Lost 2 |
| » Starters: Harry Kelley vs Bump Hadley | First | -- |
| » Lost to Athletics (52-96), 6-3 | Yankee Stadium (56-19) | 101-51 | Lost 3 |
| » Starters: Buck Ross vs Frank Makosky | First | -- |
| Friday, October 1 |
| » Lost to Red Sox (80-70), 4-2 | Yankee Stadium (56-20) | 101-52 | Lost 4 |
| » Starters: Bobo Newsom vs Lefty Gomez | First | -- |
| Saturday, October 2 |
| » Defeated Red Sox (80-71), 11-3 | Yankee Stadium (57-20) | 102-52 | |
| » Starters: Johnny Marcum vs Red Ruffing | First | -- |
| Sunday, October 3 |
| » Defeated Red Sox (80-72), 6-1 | Yankee Stadium (58-20) | 103-52 | Won 2 |
| » Starters: Joe Gonzales vs Monte Pearson | First | -- |
| Sunday, November 14 |
| Former Yankee Jack O'Connor dies in St.Louis, MO at the age of 69. |
| Saturday, November 27 |
| Future Yankee Bill Short is born in Kingston, NY. |
| Sunday, December 12 |
| Future Yankee Pedro Gonzales is born in San Pedro de Macoris, D.R. |
Game information provided by Retrosheet (www.retrosheet.org) |