| Sunday, January 10 |
| Future White Sox Jim O'Toole is born in Chicago, IL. |
| Friday, January 15 |
| Future White Sox Bob Sadowski is born in St. Louis, MO. |
| Tuesday, February 2 |
| Future White Sox Don Buford is born in Linden, TX. |
| Sunday, February 7 |
| Future White Sox Juan Pizarro is born in Santurce, P.R. |
| Friday, February 12 |
| Future White Sox Stan Johnson is born in Dallas, TX. |
| Tuesday, April 6 |
| Future White Sox Phil Regan is born in Otsego, MI. |
| Saturday, April 10 |
| Future White Sox Fritz Ackley is born in Hayward, WI. |
| Tuesday, April 20 |
| » Major-league debuts: Bobby Doerr (Red Sox) |
| Wednesday, April 21 |
| » Lost to Browns (1-0), 15-10 | Sportsman's Park III (0-1) | 0-1 | |
| » Starters: Vern Kennedy vs Oral Hildebrand | Third | 1 out |
| » Major-league debuts: Johnny Rigney and Hank Steinbacher (White Sox) |
| Future White Sox Gary Peters is born in Grove City, PA. |
| Thursday, April 22 |
| » Defeated Browns (1-1), 6-1 | Sportsman's Park III (1-1) | 1-1 | |
| » Starters: Monty Stratton vs Jack Knott | Second | ½ out |
| Friday, April 23 |
| » Lost to Tigers (2-0), 10-2 | Comiskey Park I (0-1) | 1-2 | |
| » Starters: Roxie Lawson vs Sugar Cain | Fifth | 1½ out |
| Sunday, April 25 |
| » Defeated Tigers (2-1), 11-7 | Comiskey Park I (1-1) | 2-2 | |
| » Starters: Elden Auker vs Vern Kennedy | Third | 1 out |
| Wednesday, April 28 |
| » Lost to Indians (3-2), 7-2 | League Park II (0-1) | 2-3 | |
| » Starters: Thornton Lee vs Mel Harder | Fifth | 2 out |
| Thursday, April 29 |
| » Defeated Browns (2-5), 12-0 | Comiskey Park I (2-1) | 3-3 | |
| » Starters: Jim Walkup vs Monty Stratton | Fifth | 2 out |
| Saturday, May 1 |
| » Lost to Tigers (5-2), 11-4 | Tiger Stadium (0-1) | 3-4 | |
| » Starters: Ted Lyons vs Tommy Bridges | Sixth | 2½ out |
| Sunday, May 2 |
| » Lost to Tigers (6-2), 6-5 | Tiger Stadium (0-2) | 3-5 | Lost 2 |
| » Starters: Vern Kennedy vs Roxie Lawson | Fifth | 3 out |
| Monday, May 3 |
| » Lost to Tigers (7-2), 12-9 | Tiger Stadium (0-3) | 3-6 | Lost 3 |
| » Starters: Sugar Cain vs Pat McLaughlin | Sixth | 4 out |
| Wednesday, May 5 |
| » Lost to Athletics (5-4), 7-6 | Comiskey Park I (2-2) | 3-7 | Lost 4 |
| » Starters: Lynn Nelson vs Monty Stratton | Eighth | 4½ out |
| Thursday, May 6 |
| » Lost to Athletics (6-4), 3-1 | Comiskey Park I (2-3) | 3-8 | Lost 5 |
| » Starters: Bud Thomas vs Johnny Rigney | Seventh | 4½ out |
| Friday, May 7 |
| » Lost to Red Sox (7-3), 5-3 | Comiskey Park I (2-4) | 3-9 | Lost 6 |
| » Starters: Lefty Grove vs Vern Kennedy | Seventh | 5 out |
| Future White Sox Claude Raymond is born in St. Jean, PQ. |
| Saturday, May 8 |
| » Defeated Red Sox (7-4), 6-5 | Comiskey Park I (3-4) | 4-9 | |
| » Starters: Wes Ferrell vs Bill Dietrich | Seventh | 4½ out |
| Sunday, May 9 |
| » Defeated Yankees (8-7), 2-1 | Comiskey Park I (4-4) | 5-9 | Won 2 |
| » Starters: Spud Chandler vs Thornton Lee | Sixth | 3½ out |
| Monday, May 10 |
| » Lost to Yankees (9-7), 7-0 | Comiskey Park I (4-5) | 5-10 | |
| » Starters: Monte Pearson vs Ted Lyons | Sixth | 4½ out |
| Tuesday, May 11 |
| » Defeated Yankees (9-8), 7-2 | Comiskey Park I (5-5) | 6-10 | |
| » Starters: Bump Hadley vs Monty Stratton | Sixth | 4½ out |
| Wednesday, May 12 |
| » Defeated Senators (6-12), 13-5 | Comiskey Park I (6-5) | 7-10 | Won 2 |
| » Starters: Bobo Newsom vs Vern Kennedy | Fifth | 4 out |
| Thursday, May 13 |
| » Lost to Senators (7-12), 10-2 | Comiskey Park I (6-6) | 7-11 | |
| » Starters: Jimmie DeShong vs Thornton Lee | Fifth | 4½ out |
| Saturday, May 15 |
| » Defeated Indians (9-7), 6-0 | Comiskey Park I (7-6) | 8-11 | |
| » Starters: Denny Galehouse vs Monty Stratton | Seventh | 3½ out |
| Sunday, May 16 |
| » Defeated Indians (9-8), 6-4 | Comiskey Park I (8-6) | 9-11 | Won 2 |
| » Starters: Ivy Andrews vs Vern Kennedy | Fifth | 3 out |
| Tuesday, May 18 |
| » Lost to Yankees (13-9), 4-0 | Yankee Stadium (0-1) | 9-12 | |
| » Starters: Ted Lyons vs Spud Chandler | Seventh | 4 out |
| Thursday, May 20 |
| » Defeated Yankees (13-10), 3-1 | Yankee Stadium (1-1) | 10-12 | |
| » Starters: Thornton Lee vs Johnny Broaca | Sixth | 2½ out |
| Friday, May 21 |
| » Lost to Athletics (13-9), 4-3 | Shibe Park (0-1) | 10-13 | |
| » Starters: Monty Stratton vs George Caster | Sixth | 3½ out |
| Saturday, May 22 |
| » Lost to Athletics (14-9), 10-9 | Shibe Park (0-2) | 10-14 | Lost 2 |
| » Starters: Vern Kennedy vs Lynn Nelson | Seventh | 4½ out |
| Former White Sox Hi Jasper dies in St.Louis, MO at the age of 57. |
| Sunday, May 23 |
| » Defeated Red Sox (10-13), 6-4 | Fenway Park (1-0) | 11-14 | |
| » Starters: John Whitehead vs Johnny Marcum | Sixth | 4½ out |
| Monday, May 24 |
| » Lost to Red Sox (11-13), 9-5 | Fenway Park (1-1) | 11-15 | |
| » Starters: Johnny Rigney vs Rube Walberg | Seventh | 5½ out |
| Tuesday, May 25 |
| » Defeated Senators (13-17), 9-2 | Griffith Stadium (1-0) | 12-15 | |
| » Starters: Ted Lyons vs Jimmie DeShong | Sixth | 5½ out |
| Wednesday, May 26 |
| » Defeated Senators (13-18), 6-5 | Griffith Stadium (2-0) | 13-15 | Won 2 |
| » Starters: Thornton Lee vs Carl Fischer | Sixth | 5½ out |
| Thursday, May 27 |
| » Lost to Senators (14-18), 2-1 | Griffith Stadium (2-1) | 13-16 | |
| » Starters: Monty Stratton vs Monte Weaver | Sixth | 5½ out |
| Friday, May 28 |
| » Defeated Indians (15-12), 3-2 | League Park II (1-1) | 14-16 | |
| » Starters: Vern Kennedy vs Denny Galehouse | Sixth | 5 out |
| Saturday, May 29 |
| » Defeated Indians (15-13), 4-1 | League Park II (2-1) | 15-16 | Won 2 |
| » Starters: John Whitehead vs Mel Harder | Sixth | 6 out |
| » Lost to Indians (16-13), 15-3 | League Park II (2-2) | 15-17 | |
| » Starters: Bill Dietrich vs Johnny Allen | Sixth | 6 out |
| Sunday, May 30 |
| » Defeated Indians (16-14), 9-6 | Cleveland Stadium (1-0) | 16-17 | |
| » Starters: Ted Lyons vs Earl Whitehill | Fifth | 6 out |
| Monday, May 31 |
| » Defeated Browns (10-23), 5-2 | Comiskey Park I (9-6) | 17-17 | Won 2 |
| » Starters: Julio Bonetti vs Monty Stratton | Fifth | 5 out |
| » Defeated Browns (10-24), 9-8 | Comiskey Park I (10-6) | 18-17 | Won 3 |
| » Starters: Sheriff Blake vs Sugar Cain | Fifth | 5 out |
| Tuesday, June 1 |
| » Defeated Browns (10-25), 8-0 | Comiskey Park I (11-6) | 19-17 | Won 4 |
| » Starters: Chief Hogsett vs Bill Dietrich | Third | 4½ out |
| Thursday, June 3 |
| » Defeated Red Sox (16-16), 11-4 | Comiskey Park I (12-6) | 20-17 | Won 5 |
| » Starters: Wes Ferrell vs Vern Kennedy | Third | 4 out |
| Friday, June 4 |
| » Major-league debuts: Wayne Ambler (Athletics) |
| Saturday, June 5 |
| » Defeated Athletics (16-20), 2-0 | Comiskey Park I (13-6) | 21-17 | Won 6 |
| » Starters: George Caster vs John Whitehead | Third | 3½ out |
| Sunday, June 6 |
| » Defeated Athletics (16-21), 6-1 | Comiskey Park I (14-6) | 22-17 | Won 7 |
| » Starters: Bud Thomas vs Ted Lyons | Third | 2 out |
| » Defeated Athletics (16-22), 6-5 | Comiskey Park I (15-6) | 23-17 | Won 8 |
| » Starters: Eddie Smith vs Monty Stratton | Third | 2 out |
| Monday, June 7 |
| » Defeated Athletics (16-23), 12-6 | Comiskey Park I (16-6) | 24-17 | Won 9 |
| » Starters: George Turbeville vs Bill Dietrich | Third | 1 out |
| Tuesday, June 8 |
| » Defeated Yankees (25-17), 5-4 | Comiskey Park I (17-6) | 25-17 | Won 10 |
| » Starters: Johnny Broaca vs Thornton Lee | First | -- |
| Thursday, June 10 |
| » Lost to Yankees (26-17), 10-3 | Comiskey Park I (17-7) | 25-18 | |
| » Starters: Bump Hadley vs Vern Kennedy | Third | 1 out |
| Friday, June 11 |
| » Defeated Senators (19-26), 14-8 | Comiskey Park I (18-7) | 26-18 | |
| » Starters: Monte Weaver vs John Whitehead | Second | 1 out |
| Saturday, June 12 |
| » Lost to Senators (20-26), 6-2 | Comiskey Park I (18-8) | 26-19 | |
| » Starters: Wes Ferrell vs Johnny Rigney | Second | 1 out |
| Sunday, June 13 |
| » Defeated Senators (20-27), 9-4 | Comiskey Park I (19-8) | 27-19 | |
| » Starters: Pete Appleton vs Ted Lyons | Second | ½ out |
| » Defeated Senators (20-28), 3-2 | Comiskey Park I (20-8) | 28-19 | Won 2 |
| » Starters: Carl Fischer vs Monty Stratton | Second | ½ out |
| Tuesday, June 15 |
| » Lost to Red Sox (21-22), 5-1 | Fenway Park (1-2) | 28-20 | |
| » Starters: Vern Kennedy vs Lefty Grove | Third | 1½ out |
| Wednesday, June 16 |
| » Lost to Red Sox (22-22), 3-2 | Fenway Park (1-3) | 28-21 | Lost 2 |
| » Starters: John Whitehead vs Bobo Newsom | Third | 2½ out |
| Thursday, June 17 |
| » Lost to Red Sox (23-22), 5-2 | Fenway Park (1-4) | 28-22 | Lost 3 |
| » Starters: Bill Dietrich vs Jack Wilson | Third | 4 out |
| » Lost to Red Sox (24-22), 3-2 | Fenway Park (1-5) | 28-23 | Lost 4 |
| » Starters: Monty Stratton vs Rube Walberg | Third | 4 out |
| Saturday, June 19 |
| » Defeated Yankees (31-19), 5-2 | Yankee Stadium (2-1) | 29-23 | |
| » Starters: Thornton Lee vs Red Ruffing | Third | 3 out |
| Sunday, June 20 |
| » Lost to Yankees (32-19), 8-4 | Yankee Stadium (2-2) | 29-24 | |
| » Starters: Ted Lyons vs Lefty Gomez | Third | 5 out |
| » Lost to Yankees (33-19), 7-4 | Yankee Stadium (2-3) | 29-25 | Lost 2 |
| » Starters: John Whitehead vs Monte Pearson | Third | 5 out |
| Tuesday, June 22 |
| » Defeated Athletics (18-33), 2-0 | Shibe Park (1-2) | 30-25 | |
| » Starters: Monty Stratton vs Buck Ross | Third | 5 out |
| Wednesday, June 23 |
| » Defeated Athletics (18-34), 2-0 | Shibe Park (2-2) | 31-25 | Won 2 |
| » Starters: Bill Dietrich vs Bud Thomas | Third | 4 out |
| Thursday, June 24 |
| » Defeated Athletics (18-35), 7-2 | Shibe Park (3-2) | 32-25 | Won 3 |
| » Starters: Thornton Lee vs Harry Kelley | Third | 4 out |
| Friday, June 25 |
| » Defeated Senators (26-31), 7-6 | Griffith Stadium (3-1) | 33-25 | Won 4 |
| » Starters: John Whitehead vs Wes Ferrell | Second | 4 out |
| Saturday, June 26 |
| » Defeated Senators (26-32), 6-5 | Griffith Stadium (4-1) | 34-25 | Won 5 |
| » Starters: Vern Kennedy vs Carl Fischer | Second | 3 out |
| Sunday, June 27 |
| » Defeated Senators (26-33), 5-3 | Griffith Stadium (5-1) | 35-25 | Won 6 |
| » Starters: Ted Lyons vs Jimmie DeShong | Second | 3 out |
| Tuesday, June 29 |
| » Defeated Tigers (34-27), 3-2 | Comiskey Park I (21-8) | 36-25 | Won 7 |
| » Starters: Elden Auker vs Monty Stratton | Second | 3 out |
| Wednesday, June 30 |
| » Lost to Tigers (35-27), 4-1 | Comiskey Park I (21-9) | 36-26 | |
| » Starters: Tommy Bridges vs Thornton Lee | Second | 4 out |
| Thursday, July 1 |
| » Defeated Tigers (35-28), 15-8 | Comiskey Park I (22-9) | 37-26 | |
| » Starters: Boots Poffenberger vs Vern Kennedy | Second | 4 out |
| Friday, July 2 |
| » Lost to Browns (21-39), 4-2 | Sportsman's Park III (1-2) | 37-27 | |
| » Starters: John Whitehead vs Jim Walkup | Second | 4 out |
| Saturday, July 3 |
| » Defeated Browns (21-40), 10-5 | Sportsman's Park III (2-2) | 38-27 | |
| » Starters: Bill Dietrich vs Oral Hildebrand | Second | 4 out |
| Sunday, July 4 |
| » Defeated Browns (21-41), 4-2 | Sportsman's Park III (3-2) | 39-27 | Won 2 |
| » Starters: Ted Lyons vs Jack Knott | Second | 3½ out |
| » Defeated Browns (21-42), 9-5 | Sportsman's Park III (4-2) | 40-27 | Won 3 |
| » Starters: Monty Stratton vs Julio Bonetti | Second | 3½ out |
| Monday, July 5 |
| » Lost to Tigers (38-28), 8-4 | Tiger Stadium (0-4) | 40-28 | |
| » Starters: Vern Kennedy vs Boots Poffenberger | Third | 5½ out |
| » Lost to Tigers (39-28), 7-4 | Tiger Stadium (0-5) | 40-29 | Lost 2 |
| » Starters: Thornton Lee vs Jake Wade | Third | 5½ out |
| Friday, July 9 |
| » Defeated Browns (21-45), 11-7 | Comiskey Park I (23-9) | 41-29 | |
| » Starters: Jim Walkup vs Bill Dietrich | Third | 5½ out |
| Saturday, July 10 |
| » Defeated Browns (21-46), 5-4 | Comiskey Park I (24-9) | 42-29 | Won 2 |
| » Starters: Oral Hildebrand vs Sugar Cain | Second | 5½ out |
| Sunday, July 11 |
| » Lost to Browns (22-46), 4-1 | Comiskey Park I (24-10) | 42-30 | |
| » Starters: Jack Knott vs Ted Lyons | Third | 6 out |
| » Defeated Browns (22-47), 4-3 | Comiskey Park I (25-10) | 43-30 | |
| » Starters: Lou Koupal vs Monty Stratton | Third | 6 out |
| Tuesday, July 13 |
| » Lost to Indians (34-34), 2-1 | Comiskey Park I (25-11) | 43-31 | |
| » Starters: Denny Galehouse vs Thornton Lee | Fourth | 6½ out |
| Wednesday, July 14 |
| » Defeated Athletics (20-50), 6-4 | Comiskey Park I (26-11) | 44-31 | |
| » Starters: Buck Ross vs Vern Kennedy | Third | 6½ out |
| Thursday, July 15 |
| » Lost to Athletics (21-50), 2-1 | Comiskey Park I (26-12) | 44-32 | |
| » Starters: George Caster vs Bill Dietrich | Third | 7½ out |
| Friday, July 16 |
| » Defeated Athletics (21-51), 9-4 | Comiskey Park I (27-12) | 45-32 | |
| » Starters: Bud Thomas vs Sugar Cain | Third | 6½ out |
| Future White Sox Lee Elia is born in Philadelphia, PA. |
| Saturday, July 17 |
| » Defeated Red Sox (42-30), 4-0 | Comiskey Park I (28-12) | 46-32 | Won 2 |
| » Starters: Lefty Grove vs John Whitehead | Second | 6½ out |
| Sunday, July 18 |
| » Defeated Red Sox (42-31), 6-5 | Comiskey Park I (29-12) | 47-32 | Won 3 |
| » Starters: Bobo Newsom vs Ted Lyons | Second | 6 out |
| » Defeated Red Sox (42-32), 1-0 | Comiskey Park I (30-12) | 48-32 | Won 4 |
| » Starters: Archie McKain vs Monty Stratton | Second | 6 out |
| Monday, July 19 |
| » Defeated Red Sox (42-33), 6-4 | Comiskey Park I (31-12) | 49-32 | Won 5 |
| » Starters: Johnny Marcum vs Vern Kennedy | Second | 6 out |
| Tuesday, July 20 |
| » Defeated Senators (30-45), 4-3 | Comiskey Park I (32-12) | 50-32 | Won 6 |
| » Starters: Wes Ferrell vs Thornton Lee | Second | 6½ out |
| Wednesday, July 21 |
| » Lost to Senators (31-45), 7-3 | Comiskey Park I (32-13) | 50-33 | |
| » Starters: Jimmie DeShong vs Bill Dietrich | Second | 7½ out |
| Friday, July 23 |
| » Defeated Yankees (55-25), 9-6 | Comiskey Park I (33-13) | 51-33 | |
| » Starters: Red Ruffing vs John Whitehead | Second | 6 out |
| Saturday, July 24 |
| » Defeated Yankees (55-26), 6-5 | Comiskey Park I (34-13) | 52-33 | Won 2 |
| » Starters: Lefty Gomez vs Thornton Lee | Second | 5 out |
| Sunday, July 25 |
| » Lost to Yankees (56-26), 12-11 | Comiskey Park I (34-14) | 52-34 | |
| » Starters: Bump Hadley vs Ted Lyons | Second | 5 out |
| » Defeated Yankees (56-27), 7-6 | Comiskey Park I (35-14) | 53-34 | |
| » Starters: Pat Malone vs Monty Stratton | Second | 5 out |
| Tuesday, July 27 |
| » Lost to Senators (36-46), 6-5 | Griffith Stadium (5-2) | 53-35 | |
| » Starters: John Whitehead vs Monte Weaver | Second | 6 out |
| Wednesday, July 28 |
| » Lost to Senators (37-46), 11-8 | Griffith Stadium (5-3) | 53-36 | Lost 2 |
| » Starters: Vern Kennedy vs Ed Linke | Third | 6 out |
| Thursday, July 29 |
| » Defeated Senators (37-47), 2-0 | Griffith Stadium (6-3) | 54-36 | |
| » Starters: Thornton Lee vs Wes Ferrell | Second | 6 out |
| Saturday, July 31 |
| » Defeated Athletics (26-60), 2-0 | Shibe Park (4-2) | 55-36 | Won 2 |
| » Starters: Monty Stratton vs Harry Kelley | Second | 5½ out |
| Sunday, August 1 |
| » Defeated Athletics (26-61), 4-3 | Shibe Park (5-2) | 56-36 | Won 3 |
| » Starters: Ted Lyons vs George Caster | Second | 5 out |
| » Defeated Athletics (26-62), 5-3 | Shibe Park (6-2) | 57-36 | Won 4 |
| » Starters: Bill Dietrich vs Buck Ross | Second | 5 out |
| Tuesday, August 3 |
| » Lost to Yankees (61-29), 7-2 | Yankee Stadium (2-4) | 57-37 | |
| » Starters: Thornton Lee vs Red Ruffing | Second | 7 out |
| » Lost to Yankees (62-29), 5-3 | Yankee Stadium (2-5) | 57-38 | Lost 2 |
| » Starters: John Whitehead vs Lefty Gomez | Second | 7 out |
| Wednesday, August 4 |
| » Lost to Yankees (63-29), 10-9 | Yankee Stadium (2-6) | 57-39 | Lost 3 |
| » Starters: Vern Kennedy vs Monte Pearson | Second | 8 out |
| Thursday, August 5 |
| » Lost to Yankees (64-29), 13-8 | Yankee Stadium (2-7) | 57-40 | Lost 4 |
| » Starters: Monty Stratton vs Kemp Wicker | Third | 9 out |
| Friday, August 6 |
| » Lost to Red Sox (55-37), 7-3 | Fenway Park (1-6) | 57-41 | Lost 5 |
| » Starters: Bill Dietrich vs Jack Wilson | Third | 10 out |
| Future White Sox Cam Carreon is born in Colton, CA. Former White Sox Bruno Block dies in S.Milwaukee, WI at the age of 53. |
| Saturday, August 7 |
| » Lost to Red Sox (56-37), 5-4 | Fenway Park (1-7) | 57-42 | Lost 6 |
| » Starters: Ted Lyons vs Lefty Grove | Fourth | 11 out |
| Sunday, August 8 |
| » Lost to Red Sox (57-37), 7-6 | Fenway Park (1-8) | 57-43 | Lost 7 |
| » Starters: Vern Kennedy vs Archie McKain | Fourth | 11½ out |
| » Defeated Red Sox (57-38), 13-0 | Fenway Park (2-8) | 58-43 | |
| » Starters: John Whitehead vs Fritz Ostermueller | Fourth | 11½ out |
| Tuesday, August 10 |
| » Defeated Tigers (56-41), 6-4 | Tiger Stadium (1-5) | 59-43 | Won 2 |
| » Starters: Thornton Lee vs Elden Auker | Third | 11 out |
| Thursday, August 12 |
| » Lost to Tigers (57-41), 11-8 | Tiger Stadium (1-6) | 59-44 | |
| » Starters: Sugar Cain vs Roxie Lawson | Third | 12 out |
| » Defeated Tigers (57-42), 6-4 | Tiger Stadium (2-6) | 60-44 | |
| » Starters: John Whitehead vs Tommy Bridges | Third | 12 out |
| Friday, August 13 |
| » Lost to Indians (47-51), 7-3 | League Park II (2-3) | 60-45 | |
| » Starters: Vern Kennedy vs Mel Harder | Third | 12 out |
| Saturday, August 14 |
| » Lost to Indians (48-51), 4-3 | League Park II (2-4) | 60-46 | Lost 2 |
| » Starters: Bill Dietrich vs Johnny Allen | Fourth | 12 out |
| Future White Sox Joe Horlen is born in San Antonio, TX. |
| Sunday, August 15 |
| » Defeated Indians (48-52), 5-3 | Cleveland Stadium (2-0) | 61-46 | |
| » Starters: Ted Lyons vs Bob Feller | Third | 10½ out |
| » Defeated Indians (48-53), 3-2 | Cleveland Stadium (3-0) | 62-46 | Won 2 |
| » Starters: Thornton Lee vs Denny Galehouse | Third | 10½ out |
| Tuesday, August 17 |
| » Lost to Tigers (61-43), 11-7 | Comiskey Park I (35-15) | 62-47 | |
| » Starters: Roxie Lawson vs John Whitehead | Third | 12 out |
| Wednesday, August 18 |
| » Defeated Tigers (61-44), 6-0 | Comiskey Park I (36-15) | 63-47 | |
| » Starters: Elden Auker vs Vern Kennedy | Third | 12 out |
| Thursday, August 19 |
| » Lost to Tigers (62-44), 12-4 | Comiskey Park I (36-16) | 63-48 | |
| » Starters: Tommy Bridges vs John Whitehead | Third | 13 out |
| Friday, August 20 |
| » Lost to Indians (51-54), 7-6 | Comiskey Park I (36-17) | 63-49 | Lost 2 |
| » Starters: Denny Galehouse vs Thornton Lee | Third | 14 out |
| Sunday, August 22 |
| » Defeated Indians (51-55), 5-2 | Comiskey Park I (37-17) | 64-49 | |
| » Starters: Bob Feller vs Ted Lyons | Third | 14 out |
| » Lost to Indians (52-55), 3-2 | Comiskey Park I (37-18) | 64-50 | |
| » Starters: Mel Harder vs Vern Kennedy | Third | 14 out |
| Tuesday, August 24 |
| » Defeated Yankees (76-35), 9-8 | Comiskey Park I (38-18) | 65-50 | |
| » Starters: Red Ruffing vs John Whitehead | Third | 13 out |
| Wednesday, August 25 |
| » Lost to Yankees (77-35), 10-5 | Comiskey Park I (38-19) | 65-51 | |
| » Starters: Bump Hadley vs Thornton Lee | Third | 14 out |
| Thursday, August 26 |
| » Defeated Senators (52-58), 4-3 | Comiskey Park I (39-19) | 66-51 | |
| » Starters: Monte Weaver vs Vern Kennedy | Third | 14 out |
| Friday, August 27 |
| » Lost to Senators (53-58), 5-0 | Comiskey Park I (39-20) | 66-52 | |
| » Starters: Pete Appleton vs Bill Dietrich | Third | 15 out |
| Saturday, August 28 |
| » Defeated Senators (53-59), 3-2 | Comiskey Park I (40-20) | 67-52 | |
| » Starters: Wes Ferrell vs Ted Lyons | Third | 14 out |
| Sunday, August 29 |
| » Lost to Athletics (36-78), 16-0 | Comiskey Park I (40-21) | 67-53 | |
| » Starters: George Caster vs Monty Stratton | Third | 14½ out |
| » Defeated Athletics (36-79), 5-3 | Comiskey Park I (41-21) | 68-53 | |
| » Starters: Harry Kelley vs John Whitehead | Third | 14½ out |
| Tuesday, August 31 |
| » Defeated Red Sox (64-52), 7-6 | Comiskey Park I (42-21) | 69-53 | Won 2 |
| » Starters: Jack Wilson vs Vern Kennedy | Third | 14 out |
| Wednesday, September 1 |
| » Lost to Red Sox (65-52), 2-0 | Comiskey Park I (42-22) | 69-54 | |
| » Starters: Lefty Grove vs Bill Dietrich | Third | 14 out |
| Thursday, September 2 |
| » Defeated Red Sox (65-53), 4-2 | Comiskey Park I (43-22) | 70-54 | |
| » Starters: Johnny Marcum vs Thornton Lee | Third | 12½ out |
| » Defeated Red Sox (65-54), 10-8 | Comiskey Park I (44-22) | 71-54 | Won 2 |
| » Starters: Archie McKain vs John Whitehead | Third | 12½ out |
| Friday, September 3 |
| » Lost to Tigers (72-50), 4-3 | Tiger Stadium (2-7) | 71-55 | |
| » Starters: Vern Kennedy vs Elden Auker | Third | 12½ out |
| Saturday, September 4 |
| » Defeated Tigers (72-51), 9-1 | Tiger Stadium (3-7) | 72-55 | |
| » Starters: Bill Dietrich vs Tommy Bridges | Third | 12½ out |
| Sunday, September 5 |
| » Defeated Tigers (72-52), 5-2 | Tiger Stadium (4-7) | 73-55 | Won 2 |
| » Starters: John Whitehead vs Roxie Lawson | Third | 12½ out |
| Monday, September 6 |
| » Defeated Indians (65-59), 2-1 | League Park II (3-4) | 74-55 | Won 3 |
| » Starters: Ted Lyons vs Willis Hudlin | Third | 13½ out |
| » Lost to Indians (66-59), 2-1 | League Park II (3-5) | 74-56 | |
| » Starters: Thornton Lee vs Bob Feller | Third | 13½ out |
| Wednesday, September 8 |
| » Defeated Browns (38-90), 10-1 | Sportsman's Park III (5-2) | 75-56 | |
| » Starters: Vern Kennedy vs Jack Knott | Third | 14 out |
| Thursday, September 9 |
| » Defeated Browns (38-91), 9-8 | Sportsman's Park III (6-2) | 76-56 | Won 2 |
| » Starters: Johnny Rigney vs Bill Trotter | Third | 13 out |
| Saturday, September 11 |
| » Lost to Tigers (77-54), 9-5 | Comiskey Park I (44-23) | 76-57 | |
| » Starters: Elden Auker vs Bill Dietrich | Third | 14 out |
| » Lost to Tigers (78-54), 4-2 | Comiskey Park I (44-24) | 76-58 | Lost 2 |
| » Starters: Roxie Lawson vs John Whitehead | Third | 14 out |
| Sunday, September 12 |
| » Lost to Tigers (79-54), 4-0 | Comiskey Park I (44-25) | 76-59 | Lost 3 |
| » Starters: Tommy Bridges vs Vern Kennedy | Third | 14½ out |
| Wednesday, September 15 |
| » Defeated Red Sox (71-61), 5-3 | Fenway Park (3-8) | 77-59 | |
| » Starters: Bill Dietrich vs Lefty Grove | Third | 14½ out |
| Future White Sox Charley Smith is born in Charleston, SC. |
| Saturday, September 18 |
| » Lost to Yankees (93-44), 12-8 | Yankee Stadium (2-8) | 77-60 | |
| » Starters: Thornton Lee vs Red Ruffing | Third | 17 out |
| » Lost to Yankees (94-44), 4-0 | Yankee Stadium (2-9) | 77-61 | Lost 2 |
| » Starters: John Whitehead vs Ivy Andrews | Third | 17 out |
| Sunday, September 19 |
| » Lost to Senators (67-72), 5-4 | Griffith Stadium (6-4) | 77-62 | Lost 3 |
| » Starters: Ted Lyons vs Ken Chase | Third | 16½ out |
| » Defeated Senators (67-73), 9-1 | Griffith Stadium (7-4) | 78-62 | |
| » Starters: Vern Kennedy vs Red Anderson | Third | 16½ out |
| » Major-league debuts: Mike Guerra (Senators) |
| Tuesday, September 21 |
| » Lost to Athletics (48-91), 5-4 | Shibe Park (6-3) | 78-63 | |
| » Starters: Bill Cox vs Al Williams | Third | 17½ out |
| Wednesday, September 22 |
| » Defeated Athletics (48-92), 9-3 | Shibe Park (7-3) | 79-63 | |
| » Starters: Thornton Lee vs Harry Kelley | Third | 18 out |
| Thursday, September 23 |
| » Defeated Athletics (48-93), 1-0 | Shibe Park (8-3) | 80-63 | Won 2 |
| » Starters: John Whitehead vs Buck Ross | Third | 17 out |
| Saturday, September 25 |
| » Lost to Browns (44-101), 4-3 | Comiskey Park I (44-26) | 80-64 | |
| » Starters: Les Tietje vs Bill Dietrich | Third | 18½ out |
| Sunday, September 26 |
| » Defeated Browns (44-102), 4-3 | Comiskey Park I (45-26) | 81-64 | |
| » Starters: Harry Kimberlin vs Ted Lyons | Third | 17 out |
| » Defeated Browns (44-103), 4-1 | Comiskey Park I (46-26) | 82-64 | Won 2 |
| » Starters: Lou Koupal vs Vern Kennedy | Third | 17 out |
| Tuesday, September 28 |
| » Lost to Indians (79-70), 7-6 | Comiskey Park I (46-27) | 82-65 | |
| » Starters: Willis Hudlin vs Thornton Lee | Third | 17½ out |
| Wednesday, September 29 |
| » Lost to Indians (80-70), 5-4 | Comiskey Park I (46-28) | 82-66 | Lost 2 |
| » Starters: Earl Whitehill vs Bill Dietrich | Third | 17½ out |
| » Defeated Indians (80-71), 1-0 | Comiskey Park I (47-28) | 83-66 | |
| » Starters: Whit Wyatt vs Bill Cox | Third | 17½ out |
| Thursday, September 30 |
| » Lost to Indians (81-71), 6-4 | Comiskey Park I (47-29) | 83-67 | |
| » Starters: Johnny Allen vs Ted Lyons | Third | 17½ out |
| » Lost to Indians (82-71), 4-1 | Comiskey Park I (47-30) | 83-68 | Lost 2 |
| » Starters: Bob Feller vs Vern Kennedy | Third | 17½ out |
| Saturday, October 2 |
| » Defeated Browns (46-106), 8-2 | Sportsman's Park III (7-2) | 84-68 | |
| » Starters: John Whitehead vs Bill Miller | Third | 17 out |
| » Major-league debuts: Bill Miller (Browns) |
| Sunday, October 3 |
| » Defeated Browns (46-107), 2-0 | Sportsman's Park III (8-2) | 85-68 | Won 2 |
| » Starters: Thornton Lee vs Les Tietje | Third | 16½ out |
| » Defeated Browns (46-108), 7-2 | Sportsman's Park III (9-2) | 86-68 | Won 3 |
| » Starters: Monty Stratton vs Lefty Mills | Third | 16½ out |
| Sunday, October 31 |
| Former White Sox Ed Walsh dies in Meriden, CT at the age of 33. |
| Monday, November 15 |
| Future White Sox Bob Farley is born in Watsontown, PA. |
Game information provided by Retrosheet (www.retrosheet.org) |
