| Friday, January 8 |
| Future Indian Don Dillard is born in Greenville, SC. |
| Monday, January 11 |
| Future Indian Jack Curtis is born in Rhodhiss, NC. |
| Thursday, January 14 |
| Future Indian Sonny Siebert is born in St. Marys, MO. |
| Sunday, February 7 |
| Future Indian Juan Pizarro is born in Santurce, P.R. |
| Friday, April 2 |
| Future Indian Dick Radatz is born in Detroit, MI. |
| Sunday, April 4 |
| Future Indian Gary Geiger is born in Sand Ridge, IL. |
| Tuesday, April 20 |
| » Lost to Tigers (1-0), 4-3 | Tiger Stadium (0-1) | 0-1 | |
| » Starters: Mel Harder vs Elden Auker | Fourth | 1 out |
| Friday, April 23 |
| » Defeated Browns (1-2), 9-2 | League Park II (1-0) | 1-1 | |
| » Starters: Chief Hogsett vs Johnny Allen | Fourth | 1 out |
| » Major-league debuts: Ben Huffman and Bill Trotter (Browns) |
| Saturday, April 24 |
| » Lost to Browns (2-2), 4-3 | League Park II (1-1) | 1-2 | |
| » Starters: Jim Walkup vs Bob Feller | Fifth | 1½ out |
| Sunday, April 25 |
| » Defeated Browns (2-3), 5-4 | Cleveland Stadium (1-0) | 2-2 | |
| » Starters: Julio Bonetti vs Denny Galehouse | Third | 1 out |
| Monday, April 26 |
| » Major-league debuts: Lou Fette (Braves) |
| Wednesday, April 28 |
| » Defeated White Sox (2-3), 7-2 | League Park II (2-1) | 3-2 | Won 2 |
| » Starters: Thornton Lee vs Mel Harder | Third | 1 out |
| Thursday, April 29 |
| » Defeated Tigers (3-2), 12-3 | League Park II (3-1) | 4-2 | Won 3 |
| » Starters: Elden Auker vs Earl Whitehill | Second | 1 out |
| Friday, April 30 |
| » Lost to Tigers (4-2), 4-2 | League Park II (3-2) | 4-3 | |
| » Starters: Jake Wade vs Lloyd Brown | Fourth | 1 out |
| Saturday, May 1 |
| » Lost to Browns (3-5), 3-2 | Sportsman's Park III (0-1) | 4-4 | Lost 2 |
| » Starters: Denny Galehouse vs Chief Hogsett | Fifth | 2 out |
| Tuesday, May 4 |
| » Lost to Senators (4-7), 12-5 | League Park II (3-3) | 4-5 | Lost 3 |
| » Starters: Bobo Newsom vs Mel Harder | Fourth | 2½ out |
| Wednesday, May 5 |
| » Major-league debuts: Chet Laabs (Tigers) |
| Thursday, May 6 |
| » Defeated Senators (4-8), 4-2 | League Park II (4-3) | 5-5 | |
| » Starters: Monte Weaver vs Lloyd Brown | Fourth | 2 out |
| Friday, May 7 |
| » Defeated Yankees (8-5), 7-6 | League Park II (5-3) | 6-5 | Won 2 |
| » Starters: Bump Hadley vs Denny Galehouse | Fourth | 1½ out |
| Saturday, May 8 |
| » Defeated Yankees (8-6), 4-0 | League Park II (6-3) | 7-5 | Won 3 |
| » Starters: Lefty Gomez vs Ivy Andrews | Third | 1 out |
| Sunday, May 9 |
| » Defeated Red Sox (7-5), 3-1 | Cleveland Stadium (2-0) | 8-5 | Won 4 |
| » Starters: Rube Walberg vs Willis Hudlin | First | -- |
| Monday, May 10 |
| » Defeated Red Sox (7-6), 6-5 | League Park II (7-3) | 9-5 | Won 5 |
| » Starters: Johnny Marcum vs Earl Whitehill | First | -- |
| Tuesday, May 11 |
| » Lost to Red Sox (8-6), 11-4 | League Park II (7-4) | 9-6 | |
| » Starters: Jack Wilson vs Lloyd Brown | Second | 1 out |
| Saturday, May 15 |
| » Lost to White Sox (8-11), 6-0 | Comiskey Park I (0-1) | 9-7 | Lost 2 |
| » Starters: Denny Galehouse vs Monty Stratton | Third | 1 out |
| Sunday, May 16 |
| » Lost to White Sox (9-11), 6-4 | Comiskey Park I (0-2) | 9-8 | Lost 3 |
| » Starters: Ivy Andrews vs Vern Kennedy | Third | 1½ out |
| Tuesday, May 18 |
| » Defeated Red Sox (9-10), 7-4 | Fenway Park (1-0) | 10-8 | |
| » Starters: Mel Harder vs Rube Walberg | Third | 1½ out |
| Thursday, May 20 |
| » Defeated Red Sox (9-11), 16-5 | Fenway Park (2-0) | 11-8 | Won 2 |
| » Starters: Johnny Allen vs Johnny Marcum | First | -- |
| Friday, May 21 |
| » Defeated Senators (12-14), 7-5 | Griffith Stadium (1-0) | 12-8 | Won 3 |
| » Starters: Earl Whitehill vs Jimmie DeShong | First | -- |
| Saturday, May 22 |
| » Lost to Senators (13-14), 4-1 | Griffith Stadium (1-1) | 12-9 | |
| » Starters: Lloyd Brown vs Carl Fischer | Third | 1 out |
| Former Indian Hi Jasper dies in St.Louis, MO at the age of 57. |
| Sunday, May 23 |
| » Lost to Yankees (16-10), 7-3 | Yankee Stadium (0-1) | 12-10 | Lost 2 |
| » Starters: Denny Galehouse vs Red Ruffing | Fourth | 2 out |
| Monday, May 24 |
| » Lost to Yankees (17-10), 14-0 | Yankee Stadium (0-2) | 12-11 | Lost 3 |
| » Starters: Ivy Andrews vs Spud Chandler | Fourth | 3 out |
| Tuesday, May 25 |
| » Defeated Athletics (15-11), 4-2 | Shibe Park (1-0) | 13-11 | |
| » Starters: Mel Harder vs Eddie Smith | Fourth | 3 out |
| Wednesday, May 26 |
| » Defeated Athletics (15-12), 8-6 | Shibe Park (2-0) | 14-11 | Won 2 |
| » Starters: Johnny Allen vs Harry Kelley | Second | 3 out |
| Thursday, May 27 |
| » Defeated Athletics (15-13), 8-7 | Shibe Park (3-0) | 15-11 | Won 3 |
| » Starters: Earl Whitehill vs George Caster | Second | 2 out |
| Friday, May 28 |
| » Lost to White Sox (14-16), 3-2 | League Park II (7-5) | 15-12 | |
| » Starters: Vern Kennedy vs Denny Galehouse | Third | 2½ out |
| Saturday, May 29 |
| » Lost to White Sox (15-16), 4-1 | League Park II (7-6) | 15-13 | Lost 2 |
| » Starters: John Whitehead vs Mel Harder | Third | 3½ out |
| » Defeated White Sox (15-17), 15-3 | League Park II (8-6) | 16-13 | |
| » Starters: Bill Dietrich vs Johnny Allen | Third | 3½ out |
| Sunday, May 30 |
| » Lost to White Sox (16-17), 9-6 | Cleveland Stadium (2-1) | 16-14 | |
| » Starters: Ted Lyons vs Earl Whitehill | Third | 4½ out |
| Monday, May 31 |
| » Defeated Tigers (20-16), 7-1 | League Park II (9-6) | 17-14 | |
| » Starters: Jake Wade vs Willis Hudlin | Second | 3½ out |
| » Defeated Tigers (20-17), 6-5 | League Park II (10-6) | 18-14 | Won 2 |
| » Starters: Tommy Bridges vs Ivy Andrews | Second | 3½ out |
| Tuesday, June 1 |
| » Defeated Tigers (20-18), 4-3 | League Park II (11-6) | 19-14 | Won 3 |
| » Starters: Elden Auker vs Denny Galehouse | Second | 3 out |
| Wednesday, June 2 |
| » Lost to Yankees (24-12), 8-4 | League Park II (11-7) | 19-15 | |
| » Starters: Red Ruffing vs Earl Whitehill | Second | 4 out |
| Thursday, June 3 |
| » Defeated Yankees (24-13), 6-2 | League Park II (12-7) | 20-15 | |
| » Starters: Lefty Gomez vs Mel Harder | Second | 3 out |
| Friday, June 4 |
| » Defeated Yankees (24-14), 5-3 | League Park II (13-7) | 21-15 | Won 2 |
| » Starters: Spud Chandler vs Johnny Allen | Second | 2 out |
| Saturday, June 5 |
| » Defeated Senators (18-23), 8-6 | League Park II (14-7) | 22-15 | Won 3 |
| » Starters: Carl Fischer vs Willis Hudlin | Second | 2 out |
| Sunday, June 6 |
| » Lost to Senators (19-23), 8-7 | Cleveland Stadium (2-2) | 22-16 | |
| » Starters: Monte Weaver vs Denny Galehouse | Second | 2 out |
| Monday, June 7 |
| » Defeated Senators (19-24), 17-5 | League Park II (15-7) | 23-16 | |
| » Starters: Joe Cascarella vs Earl Whitehill | Second | 1 out |
| Tuesday, June 8 |
| » Lost to Red Sox (19-18), 10-8 | League Park II (15-8) | 23-17 | |
| » Starters: Archie McKain vs Johnny Allen | Second | 1 out |
| Wednesday, June 9 |
| » Defeated Red Sox (19-19), 12-6 | League Park II (16-8) | 24-17 | |
| » Starters: Fritz Ostermueller vs Mel Harder | Second | ½ out |
| Friday, June 11 |
| » Lost to Athletics (17-25), 11-3 | League Park II (16-9) | 24-18 | |
| » Starters: Buck Ross vs Willis Hudlin | Fourth | 2 out |
| Saturday, June 12 |
| » Lost to Athletics (18-25), 3-2 | League Park II (16-10) | 24-19 | Lost 2 |
| » Starters: Harry Kelley vs Denny Galehouse | Fourth | 2 out |
| Sunday, June 13 |
| » Defeated Athletics (18-26), 2-1 | Cleveland Stadium (3-2) | 25-19 | |
| » Starters: Bud Thomas vs Johnny Allen | Fourth | 1½ out |
| » Defeated Athletics (18-27), 2-0 | Cleveland Stadium (4-2) | 26-19 | Won 2 |
| » Starters: Eddie Smith vs Earl Whitehill | Fourth | 1½ out |
| Tuesday, June 15 |
| » Lost to Yankees (29-18), 3-0 | Yankee Stadium (0-3) | 26-20 | |
| » Starters: Mel Harder vs Red Ruffing | Fourth | 2½ out |
| Wednesday, June 16 |
| » Lost to Yankees (30-18), 4-1 | Yankee Stadium (0-4) | 26-21 | Lost 2 |
| » Starters: Denny Galehouse vs Lefty Gomez | Fourth | 3½ out |
| Thursday, June 17 |
| » Lost to Yankees (31-18), 9-7 | Yankee Stadium (0-5) | 26-22 | Lost 3 |
| » Starters: Earl Whitehill vs Bump Hadley | Fourth | 4½ out |
| Friday, June 18 |
| » Lost to Red Sox (25-22), 5-4 | Fenway Park (2-1) | 26-23 | Lost 4 |
| » Starters: Johnny Allen vs Fritz Ostermueller | Fifth | 5 out |
| Sunday, June 20 |
| » Lost to Red Sox (26-22), 5-2 | Fenway Park (2-2) | 26-24 | Lost 5 |
| » Starters: Willis Hudlin vs Lefty Grove | Fifth | 5½ out |
| » Defeated Red Sox (26-23), 8-7 | Fenway Park (3-2) | 27-24 | |
| » Starters: Mel Harder vs Bobo Newsom | Fifth | 5½ out |
| Tuesday, June 22 |
| » Lost to Senators (24-30), 11-2 | Griffith Stadium (1-2) | 27-25 | |
| » Starters: Earl Whitehill vs Carl Fischer | Fifth | 6½ out |
| Wednesday, June 23 |
| » Lost to Senators (25-30), 14-5 | Griffith Stadium (1-3) | 27-26 | Lost 2 |
| » Starters: Denny Galehouse vs Jimmie DeShong | Fifth | 6½ out |
| Thursday, June 24 |
| » Lost to Senators (26-30), 8-2 | Griffith Stadium (1-4) | 27-27 | Lost 3 |
| » Starters: Lloyd Brown vs Monte Weaver | Fifth | 7½ out |
| Saturday, June 26 |
| » Lost to Athletics (19-35), 7-0 | Shibe Park (3-1) | 27-28 | Lost 4 |
| » Starters: Mel Harder vs Buck Ross | Fourth | 8 out |
| Sunday, June 27 |
| » Lost to Athletics (20-35), 10-0 | Shibe Park (3-2) | 27-29 | Lost 5 |
| » Starters: Denny Galehouse vs George Caster | Fifth | 8½ out |
| » Defeated Athletics (20-36), 7-2 | Shibe Park (4-2) | 28-29 | |
| » Starters: Willis Hudlin vs Harry Kelley | Fifth | 8½ out |
| Tuesday, June 29 |
| » Defeated Browns (20-38), 7-5 | League Park II (17-10) | 29-29 | Won 2 |
| » Starters: Chief Hogsett vs Earl Whitehill | Fifth | 8½ out |
| Wednesday, June 30 |
| » Defeated Browns (20-39), 10-3 | League Park II (18-10) | 30-29 | Won 3 |
| » Starters: Julio Bonetti vs Mel Harder | Fifth | 8½ out |
| Thursday, July 1 |
| Future Indian Ron Nischwitz is born in Dayton, OH. |
| Saturday, July 3 |
| » Lost to Tigers (36-28), 9-5 | League Park II (18-11) | 30-30 | |
| » Starters: Jake Wade vs Denny Galehouse | Fifth | 9½ out |
| Sunday, July 4 |
| » Lost to Tigers (37-28), 3-2 | Cleveland Stadium (4-3) | 30-31 | Lost 2 |
| » Starters: Elden Auker vs Bob Feller | Fifth | 10½ out |
| Monday, July 5 |
| » Defeated Browns (21-43), 14-4 | Sportsman's Park III (1-1) | 31-31 | |
| » Starters: Willis Hudlin vs Oral Hildebrand | Fifth | 10½ out |
| » Defeated Browns (21-44), 15-4 | Sportsman's Park III (2-1) | 32-31 | Won 2 |
| » Starters: Earl Whitehill vs Chief Hogsett | Fifth | 10½ out |
| Friday, July 9 |
| » Lost to Tigers (40-28), 10-8 | Tiger Stadium (0-2) | 32-32 | |
| » Starters: Willis Hudlin vs Elden Auker | Fifth | 11½ out |
| Saturday, July 10 |
| » Lost to Tigers (41-28), 12-11 | Tiger Stadium (0-3) | 32-33 | Lost 2 |
| » Starters: Earl Whitehill vs Jake Wade | Fifth | 12 out |
| » Defeated Tigers (41-29), 8-7 | Tiger Stadium (1-3) | 33-33 | |
| » Starters: Mel Harder vs Tommy Bridges | Fifth | 12 out |
| Sunday, July 11 |
| » Lost to Tigers (42-29), 3-2 | Tiger Stadium (1-4) | 33-34 | |
| » Starters: Bob Feller vs Boots Poffenberger | Fifth | 13 out |
| Tuesday, July 13 |
| » Defeated White Sox (43-31), 2-1 | Comiskey Park I (1-2) | 34-34 | |
| » Starters: Denny Galehouse vs Thornton Lee | Fifth | 12½ out |
| Wednesday, July 14 |
| » Defeated Senators (30-39), 11-3 | League Park II (19-11) | 35-34 | Won 2 |
| » Starters: Carl Fischer vs Willis Hudlin | Fifth | 12½ out |
| Thursday, July 15 |
| » Defeated Senators (30-40), 6-2 | League Park II (20-11) | 36-34 | Won 3 |
| » Starters: Ken Chase vs Earl Whitehill | Fifth | 12½ out |
| Friday, July 16 |
| » Defeated Senators (30-41), 11-5 | League Park II (21-11) | 37-34 | Won 4 |
| » Starters: Wes Ferrell vs Mel Harder | Fifth | 11½ out |
| Saturday, July 17 |
| » Lost to Yankees (50-23), 9-6 | League Park II (21-12) | 37-35 | |
| » Starters: Bump Hadley vs Denny Galehouse | Fifth | 12½ out |
| Sunday, July 18 |
| » Lost to Yankees (51-23), 5-1 | Cleveland Stadium (4-4) | 37-36 | Lost 2 |
| » Starters: Red Ruffing vs Bob Feller | Fifth | 13½ out |
| Monday, July 19 |
| » Lost to Yankees (52-23), 8-5 | League Park II (21-13) | 37-37 | Lost 3 |
| » Starters: Lefty Gomez vs Willis Hudlin | Fifth | 14½ out |
| Tuesday, July 20 |
| » Lost to Athletics (23-53), 7-5 | League Park II (21-14) | 37-38 | Lost 4 |
| » Starters: George Caster vs Earl Whitehill | Fifth | 16 out |
| Wednesday, July 21 |
| » Defeated Athletics (23-54), 9-8 | League Park II (22-14) | 38-38 | |
| » Starters: Bud Thomas vs Mel Harder | Fifth | 15½ out |
| » Defeated Athletics (23-55), 8-7 | League Park II (23-14) | 39-38 | Won 2 |
| » Starters: Buck Ross vs Denny Galehouse | Fifth | 15½ out |
| Thursday, July 22 |
| » Defeated Athletics (23-56), 5-1 | League Park II (24-14) | 40-38 | Won 3 |
| » Starters: Eddie Smith vs Whit Wyatt | Fifth | 14½ out |
| Friday, July 23 |
| » Lost to Red Sox (44-35), 6-2 | League Park II (24-15) | 40-39 | |
| » Starters: Archie McKain vs Willis Hudlin | Fifth | 14½ out |
| Saturday, July 24 |
| » Defeated Red Sox (44-36), 6-5 | League Park II (25-15) | 41-39 | |
| » Starters: Bobo Newsom vs Bob Feller | Fifth | 13½ out |
| Sunday, July 25 |
| » Lost to Red Sox (45-36), 4-1 | Cleveland Stadium (4-5) | 41-40 | |
| » Starters: Lefty Grove vs Earl Whitehill | Fifth | 14 out |
| Tuesday, July 27 |
| » Lost to Athletics (25-58), 4-3 | Shibe Park (4-3) | 41-41 | Lost 2 |
| » Starters: Mel Harder vs George Caster | Fifth | 15 out |
| Wednesday, July 28 |
| » Lost to Athletics (26-58), 11-7 | Shibe Park (4-4) | 41-42 | Lost 3 |
| » Starters: Whit Wyatt vs Buck Ross | Fifth | 15 out |
| Thursday, July 29 |
| » Defeated Athletics (26-59), 5-4 | Shibe Park (5-4) | 42-42 | |
| » Starters: Denny Galehouse vs Eddie Smith | Fifth | 15 out |
| Friday, July 30 |
| » Lost to Senators (38-47), 13-2 | Griffith Stadium (1-5) | 42-43 | |
| » Starters: Earl Whitehill vs Jimmie DeShong | Fifth | 16 out |
| Saturday, July 31 |
| » Lost to Senators (39-47), 3-0 | Griffith Stadium (1-6) | 42-44 | Lost 2 |
| » Starters: Willis Hudlin vs Pete Appleton | Fifth | 16 out |
| Sunday, August 1 |
| » Defeated Senators (39-48), 11-2 | Griffith Stadium (2-6) | 43-44 | |
| » Starters: Bob Feller vs Bucky Jacobs | Fifth | 16 out |
| Tuesday, August 3 |
| » Lost to Red Sox (51-37), 13-2 | Fenway Park (3-3) | 43-45 | |
| » Starters: Mel Harder vs Lefty Grove | Fifth | 17½ out |
| Wednesday, August 4 |
| » Lost to Red Sox (52-37), 8-6 | Fenway Park (3-4) | 43-46 | Lost 2 |
| » Starters: Denny Galehouse vs Archie McKain | Fifth | 19 out |
| » Lost to Red Sox (53-37), 6-5 | Fenway Park (3-5) | 43-47 | Lost 3 |
| » Starters: Whit Wyatt vs Fritz Ostermueller | Fifth | 19 out |
| Thursday, August 5 |
| » Lost to Red Sox (54-37), 5-4 | Fenway Park (3-6) | 43-48 | Lost 4 |
| » Starters: Willis Hudlin vs Bobo Newsom | Fifth | 20 out |
| Friday, August 6 |
| » Lost to Yankees (65-29), 7-6 | Yankee Stadium (0-6) | 43-49 | Lost 5 |
| » Starters: Bob Feller vs Bump Hadley | Fifth | 21 out |
| Future Indian Cam Carreon is born in Colton, CA. Future Indian Joe Schaffernoth is born in Trenton, NJ. |
| Saturday, August 7 |
| » Lost to Yankees (66-29), 6-3 | Yankee Stadium (0-7) | 43-50 | Lost 6 |
| » Starters: Mel Harder vs Red Ruffing | Fifth | 22 out |
| Sunday, August 8 |
| » Lost to Yankees (67-29), 6-5 | Yankee Stadium (0-8) | 43-51 | Lost 7 |
| » Starters: Earl Whitehill vs Spud Chandler | Fifth | 23 out |
| Wednesday, August 11 |
| » Defeated Browns (32-65), 5-2 | League Park II (26-15) | 44-51 | |
| » Starters: Julio Bonetti vs Bob Feller | Fifth | 23 out |
| » Defeated Browns (32-66), 7-2 | League Park II (27-15) | 45-51 | Won 2 |
| » Starters: Chief Hogsett vs Denny Galehouse | Fifth | 23 out |
| Thursday, August 12 |
| » Defeated Browns (32-67), 7-0 | League Park II (28-15) | 46-51 | Won 3 |
| » Starters: Jack Knott vs Willis Hudlin | Fifth | 22½ out |
| Friday, August 13 |
| » Defeated White Sox (60-45), 7-3 | League Park II (29-15) | 47-51 | Won 4 |
| » Starters: Vern Kennedy vs Mel Harder | Fourth | 21½ out |
| Saturday, August 14 |
| » Defeated White Sox (60-46), 4-3 | League Park II (30-15) | 48-51 | Won 5 |
| » Starters: Bill Dietrich vs Johnny Allen | Fifth | 20½ out |
| Sunday, August 15 |
| » Lost to White Sox (61-46), 5-3 | Cleveland Stadium (4-6) | 48-52 | |
| » Starters: Ted Lyons vs Bob Feller | Sixth | 21 out |
| » Lost to White Sox (62-46), 3-2 | Cleveland Stadium (4-7) | 48-53 | Lost 2 |
| » Starters: Thornton Lee vs Denny Galehouse | Sixth | 21 out |
| Monday, August 16 |
| Former Indian Bunk Congalton dies in Cleveland, OH at the age of 63. |
| Wednesday, August 18 |
| » Defeated Browns (33-71), 5-2 | Sportsman's Park III (3-1) | 49-53 | |
| » Starters: Mel Harder vs Chief Hogsett | Fifth | 22½ out |
| » Lost to Browns (34-71), 11-6 | Sportsman's Park III (3-2) | 49-54 | |
| » Starters: Willis Hudlin vs Bill Trotter | Fifth | 22½ out |
| Thursday, August 19 |
| » Defeated Browns (34-72), 9-1 | Sportsman's Park III (4-2) | 50-54 | |
| » Starters: Johnny Allen vs Lou Koupal | Fifth | 22½ out |
| Friday, August 20 |
| » Defeated White Sox (63-49), 7-6 | Comiskey Park I (2-2) | 51-54 | Won 2 |
| » Starters: Denny Galehouse vs Thornton Lee | Fifth | 22½ out |
| Sunday, August 22 |
| » Lost to White Sox (64-49), 5-2 | Comiskey Park I (2-3) | 51-55 | |
| » Starters: Bob Feller vs Ted Lyons | Fifth | 22½ out |
| » Defeated White Sox (64-50), 3-2 | Comiskey Park I (3-3) | 52-55 | |
| » Starters: Mel Harder vs Vern Kennedy | Fifth | 22½ out |
| Tuesday, August 24 |
| » Defeated Red Sox (60-48), 4-3 | League Park II (31-15) | 53-55 | Won 2 |
| » Starters: Lefty Grove vs Johnny Allen | Fifth | 21½ out |
| Wednesday, August 25 |
| » Defeated Red Sox (60-49), 8-1 | League Park II (32-15) | 54-55 | Won 3 |
| » Starters: Bobo Newsom vs Bob Feller | Fifth | 22 out |
| » Lost to Red Sox (61-49), 7-2 | League Park II (32-16) | 54-56 | |
| » Starters: Archie McKain vs Willis Hudlin | Fifth | 22 out |
| Thursday, August 26 |
| » Defeated Athletics (35-76), 10-5 | League Park II (33-16) | 55-56 | |
| » Starters: Eddie Smith vs Mel Harder | Fifth | 22 out |
| Friday, August 27 |
| » Defeated Athletics (35-77), 5-3 | League Park II (34-16) | 56-56 | Won 2 |
| » Starters: Buck Ross vs Denny Galehouse | Fifth | 22 out |
| Saturday, August 28 |
| » Defeated Athletics (35-78), 5-4 | League Park II (35-16) | 57-56 | Won 3 |
| » Starters: Bud Thomas vs Earl Whitehill | Fifth | 21 out |
| Sunday, August 29 |
| » Defeated Senators (53-60), 11-4 | Cleveland Stadium (5-7) | 58-56 | Won 4 |
| » Starters: Jimmie DeShong vs Johnny Allen | Fifth | 21½ out |
| » Lost to Senators (54-60), 6-2 | Cleveland Stadium (5-8) | 58-57 | |
| » Starters: Ken Chase vs Bob Feller | Fifth | 21½ out |
| Monday, August 30 |
| » Defeated Senators (54-61), 7-6 | League Park II (36-16) | 59-57 | |
| » Starters: Monte Weaver vs Willis Hudlin | Fifth | 20½ out |
| Tuesday, August 31 |
| » Lost to Yankees (81-37), 7-3 | League Park II (36-17) | 59-58 | |
| » Starters: Bump Hadley vs Mel Harder | Fifth | 21½ out |
| Wednesday, September 1 |
| » Defeated Yankees (81-38), 4-2 | League Park II (37-17) | 60-58 | |
| » Starters: Kemp Wicker vs Denny Galehouse | Fifth | 20½ out |
| Thursday, September 2 |
| » Defeated Yankees (81-39), 4-2 | League Park II (38-17) | 61-58 | Won 2 |
| » Starters: Monte Pearson vs Bob Feller | Fifth | 19½ out |
| Friday, September 3 |
| » Defeated Browns (38-84), 15-3 | Sportsman's Park III (5-2) | 62-58 | Won 3 |
| » Starters: Johnny Allen vs Chief Hogsett | Fifth | 18½ out |
| Saturday, September 4 |
| » Defeated Browns (38-85), 5-1 | Sportsman's Park III (6-2) | 63-58 | Won 4 |
| » Starters: Mel Harder vs Jack Knott | Fifth | 18½ out |
| » Tied Browns, 3-3 | Sportsman's Park III (6-2) | 63-58 | |
| » Starters: Willis Hudlin vs Russ VanAtta | Fifth | 18½ out |
| Sunday, September 5 |
| » Defeated Browns (38-86), 9-5 | Sportsman's Park III (7-2) | 64-58 | Won 5 |
| » Starters: Denny Galehouse vs Bill Trotter | Fifth | 18 out |
| » Defeated Browns (38-87), 2-1 | Sportsman's Park III (8-2) | 65-58 | Won 6 |
| » Starters: Earl Whitehill vs Oral Hildebrand | Fifth | 18 out |
| Monday, September 6 |
| » Lost to White Sox (74-55), 2-1 | League Park II (38-18) | 65-59 | |
| » Starters: Ted Lyons vs Willis Hudlin | Fifth | 19 out |
| » Defeated White Sox (74-56), 2-1 | League Park II (39-18) | 66-59 | |
| » Starters: Thornton Lee vs Bob Feller | Fifth | 19 out |
| Wednesday, September 8 |
| » Defeated Tigers (74-53), 6-1 | Tiger Stadium (2-4) | 67-59 | Won 2 |
| » Starters: Johnny Allen vs Tommy Bridges | Fourth | 20 out |
| » Lost to Tigers (75-53), 10-5 | Tiger Stadium (2-5) | 67-60 | |
| » Starters: Mel Harder vs Elden Auker | Fourth | 20 out |
| Thursday, September 9 |
| » Lost to Tigers (76-53), 10-9 | Tiger Stadium (2-6) | 67-61 | Lost 2 |
| » Starters: Denny Galehouse vs Roxie Lawson | Fifth | 20 out |
| Friday, September 10 |
| » Defeated Tigers (76-54), 6-5 | Tiger Stadium (3-6) | 68-61 | |
| » Starters: Bob Feller vs Boots Poffenberger | Fifth | 19 out |
| Saturday, September 11 |
| » Defeated Browns (38-92), 8-0 | League Park II (40-18) | 69-61 | Won 2 |
| » Starters: Chief Hogsett vs Willis Hudlin | Fifth | 19½ out |
| » Lost to Browns (39-92), 8-3 | League Park II (40-19) | 69-62 | |
| » Starters: Jim Walkup vs Denny Galehouse | Fifth | 19½ out |
| Sunday, September 12 |
| » Defeated Browns (39-93), 6-3 | Cleveland Stadium (6-8) | 70-62 | |
| » Starters: Jack Knott vs Mel Harder | Fifth | 18½ out |
| » Defeated Browns (39-94), 6-1 | Cleveland Stadium (7-8) | 71-62 | Won 2 |
| » Starters: Russ VanAtta vs Johnny Allen | Fifth | 18½ out |
| Tuesday, September 14 |
| » Lost to Yankees (90-43), 17-5 | Yankee Stadium (0-9) | 71-63 | |
| » Starters: Earl Whitehill vs Bump Hadley | Fifth | 19½ out |
| Wednesday, September 15 |
| » Defeated Yankees (90-44), 5-4 | Yankee Stadium (1-9) | 72-63 | |
| » Starters: Bob Feller vs Joe Vance | Fifth | 19½ out |
| » Lost to Yankees (91-44), 3-1 | Yankee Stadium (1-10) | 72-64 | |
| » Starters: Denny Galehouse vs Monte Pearson | Fifth | 19½ out |
| Thursday, September 16 |
| » Lost to Yankees (92-44), 8-0 | Yankee Stadium (1-11) | 72-65 | Lost 2 |
| » Starters: Willis Hudlin vs Lefty Gomez | Fifth | 20½ out |
| Friday, September 17 |
| » Defeated Red Sox (71-62), 4-1 | Fenway Park (4-6) | 73-65 | |
| » Starters: Johnny Allen vs Bobo Newsom | Fifth | 20 out |
| Saturday, September 18 |
| » Defeated Red Sox (71-63), 7-6 | Fenway Park (5-6) | 74-65 | Won 2 |
| » Starters: Mel Harder vs Archie McKain | Fourth | 20½ out |
| Sunday, September 19 |
| » Lost to Athletics (46-91), 8-4 | Shibe Park (5-5) | 74-66 | |
| » Starters: Bob Feller vs Chubby Dean | Fifth | 21 out |
| » Lost to Athletics (47-91), 5-3 | Shibe Park (5-6) | 74-67 | Lost 2 |
| » Starters: Denny Galehouse vs George Caster | Fifth | 21 out |
| Tuesday, September 21 |
| » Defeated Senators (67-74), 6-3 | Griffith Stadium (3-6) | 75-67 | |
| » Starters: Johnny Allen vs Wes Ferrell | Fifth | 21 out |
| Wednesday, September 22 |
| » Lost to Senators (68-74), 6-4 | Griffith Stadium (3-7) | 75-68 | |
| » Starters: Mel Harder vs Jimmie DeShong | Fifth | 22½ out |
| Thursday, September 23 |
| » Lost to Senators (69-74), 3-2 | Griffith Stadium (3-8) | 75-69 | Lost 2 |
| » Starters: Willis Hudlin vs Joe Krakauskas | Fifth | 22½ out |
| Friday, September 24 |
| » Defeated Tigers (85-60), 2-1 | League Park II (41-19) | 76-69 | |
| » Starters: Jake Wade vs Denny Galehouse | Fifth | 22½ out |
| Sunday, September 26 |
| » Defeated Tigers (85-61), 9-3 | Cleveland Stadium (8-8) | 77-69 | Won 2 |
| » Starters: Roxie Lawson vs Johnny Allen | Fourth | 21½ out |
| » Defeated Tigers (85-62), 4-3 | Cleveland Stadium (9-8) | 78-69 | Won 3 |
| » Starters: Tommy Bridges vs Bob Feller | Fourth | 21½ out |
| Monday, September 27 |
| » Lost to Tigers (86-62), 2-1 | League Park II (41-20) | 78-70 | |
| » Starters: Elden Auker vs Mel Harder | Fourth | 22 out |
| Tuesday, September 28 |
| » Defeated White Sox (82-65), 7-6 | Comiskey Park I (4-3) | 79-70 | |
| » Starters: Willis Hudlin vs Thornton Lee | Fourth | 21½ out |
| Wednesday, September 29 |
| » Defeated White Sox (82-66), 5-4 | Comiskey Park I (5-3) | 80-70 | Won 2 |
| » Starters: Earl Whitehill vs Bill Dietrich | Fifth | 21½ out |
| » Lost to White Sox (83-66), 1-0 | Comiskey Park I (5-4) | 80-71 | |
| » Starters: Whit Wyatt vs Bill Cox | Fifth | 21½ out |
| Thursday, September 30 |
| » Defeated White Sox (83-67), 6-4 | Comiskey Park I (6-4) | 81-71 | |
| » Starters: Johnny Allen vs Ted Lyons | Fourth | 19½ out |
| » Defeated White Sox (83-68), 4-1 | Comiskey Park I (7-4) | 82-71 | Won 2 |
| » Starters: Bob Feller vs Vern Kennedy | Fourth | 19½ out |
| Saturday, October 2 |
| » Defeated Tigers (88-65), 12-5 | Tiger Stadium (4-6) | 83-71 | Won 3 |
| » Starters: Mel Harder vs George Gill | Fourth | 19 out |
| » Major-league debuts: Ken Keltner (Indians) |
| Sunday, October 3 |
| » Lost to Tigers (89-65), 1-0 | Tiger Stadium (4-7) | 83-72 | |
| » Starters: Johnny Allen vs Jake Wade | Fourth | 20 out |
| Tuesday, October 19 |
| Future Indian Walt Bond is born in Denmark, TN. |
| Saturday, October 23 |
| Future Indian Bob Allen is born in Tatum, TX. |
| Monday, November 15 |
| Future Indian Ray Webster is born in Grass Valley, CA. |
| Sunday, December 12 |
| Future Indian Pedro Gonzales is born in San Pedro de Macoris, D.R. |
| Monday, December 13 |
| Future Indian Ron Taylor is born in Toronto, ON. |
Game information provided by Retrosheet (www.retrosheet.org) |
