| Monday, January 11 |
| Future Cub Jack Curtis is born in Rhodhiss, NC. |
| Thursday, February 4 |
| Former Cub Harry Wolverton dies in Oakland, CA at the age of 64. |
| Saturday, February 27 |
| Future Cub Carl Warwick is born in Dallas, TX. |
| Friday, March 19 |
| Former Cub Otto Williams dies in Omaha, NE at the age of 60. |
| Friday, April 2 |
| Future Cub Dick Radatz is born in Detroit, MI. |
| Tuesday, April 6 |
| Future Cub Phil Regan is born in Otsego, MI. |
| Saturday, April 17 |
| Future Cub Roberto Pena is born in Santo Domingo, D.R. Former Cub Bill Foxen dies in Brooklyn, NY at the age of 53. |
| Tuesday, April 20 |
| » Lost to Pirates (1-0), 5-0 | Wrigley Field (0-1) | 0-1 | |
| » Starters: Cy Blanton vs Larry French | Third | 1½ out |
| Thursday, April 22 |
| » Lost to Pirates (2-0), 4-2 | Wrigley Field (0-2) | 0-2 | Lost 2 |
| » Starters: Ed Brandt vs Bill Lee | Fourth | 2 out |
| » Major-league debuts: John Bottarini and Joe Marty (Cubs) |
| Friday, April 23 |
| » Lost to Cardinals (3-0), 5-4 | Sportsman's Park III (0-1) | 0-3 | Lost 3 |
| » Starters: Charlie Root vs Lon Warneke | Fifth | 3 out |
| » Major-league debuts: Jimmy Brown and Don Padgett (Cardinals) |
| Saturday, April 24 |
| » Defeated Cardinals (3-1), 13-12 | Sportsman's Park III (1-1) | 1-3 | |
| » Starters: Roy Parmelee vs Ray Harrell | Fifth | 3 out |
| Sunday, April 25 |
| » Lost to Cardinals (4-1), 4-0 | Sportsman's Park III (1-2) | 1-4 | |
| » Starters: Bill Lee vs Dizzy Dean | Sixth | 3½ out |
| Monday, April 26 |
| » Major-league debuts: Lou Fette (Braves) |
| Wednesday, April 28 |
| » Lost to Reds (1-4), 10-3 | Wrigley Field (0-3) | 1-5 | Lost 2 |
| » Starters: Paul Derringer vs Larry French | Eighth | 4 out |
| Thursday, April 29 |
| » Lost to Pirates (5-1), 6-5 | Forbes Field (0-1) | 1-6 | Lost 3 |
| » Starters: Clyde Shoun vs Ed Brandt | Eighth | 5 out |
| Friday, April 30 |
| » Defeated Pirates (5-2), 7-2 | Forbes Field (1-1) | 2-6 | |
| » Starters: Roy Parmelee vs Russ Bauers | Sixth | 5 out |
| » Major-league debuts: Jim Tobin (Pirates) |
| Saturday, May 1 |
| » Defeated Cardinals (7-2), 11-4 | Wrigley Field (1-3) | 3-6 | Won 2 |
| » Starters: Si Johnson vs Charlie Root | Sixth | 4 out |
| » Major-league debuts: Nate Andrews (Cardinals) |
| Sunday, May 2 |
| » Defeated Cardinals (7-3), 4-1 | Wrigley Field (2-3) | 4-6 | Won 3 |
| » Starters: Bob Weiland vs Bill Lee | Sixth | 3½ out |
| » Major-league debuts: Mickey Owen (Cardinals) |
| Tuesday, May 4 |
| » Defeated Phillies (6-6), 14-7 | Baker Bowl (1-0) | 5-6 | Won 4 |
| » Starters: Roy Parmelee vs Hugh Mulcahy | Fifth | 3½ out |
| Wednesday, May 5 |
| » Defeated Phillies (6-7), 17-4 | Baker Bowl (2-0) | 6-6 | Won 5 |
| » Starters: Charlie Root vs Syl Johnson | Fourth | 3½ out |
| Thursday, May 6 |
| » Defeated Phillies (6-8), 1-0 | Baker Bowl (3-0) | 7-6 | Won 6 |
| » Starters: Bill Lee vs Claude Passeau | Third | 2½ out |
| Friday, May 7 |
| » Lost to Dodgers (6-9), 12-1 | Ebbets Field (0-1) | 7-7 | |
| » Starters: Clyde Shoun vs Fred Frankhouse | Fourth | 3½ out |
| » Major-league debuts: Newt Kimball (Cubs) |
| Saturday, May 8 |
| » Lost to Dodgers (7-9), 6-5 | Ebbets Field (0-2) | 7-8 | Lost 2 |
| » Starters: Roy Parmelee vs Harry Eisenstat | Fourth | 4 out |
| Sunday, May 9 |
| » Lost to Giants (9-7), 4-1 | Polo Grounds V (0-1) | 7-9 | Lost 3 |
| » Starters: Bill Lee vs Carl Hubbell | Fourth | 5 out |
| Monday, May 10 |
| » Defeated Giants (9-8), 4-3 | Polo Grounds V (1-1) | 8-9 | |
| » Starters: Clyde Shoun vs Hal Schumacher | Fourth | 5 out |
| Future Cub Jim Hickman is born in Henning, TN. |
| Tuesday, May 11 |
| » Lost to Giants (10-8), 10-1 | Polo Grounds V (1-2) | 8-10 | |
| » Starters: Roy Parmelee vs Slick Castleman | Fifth | 6 out |
| Wednesday, May 12 |
| » Defeated Braves (7-12), 6-2 | Braves Field (1-0) | 9-10 | |
| » Starters: Charlie Root vs Johnny Lanning | Fifth | 6 out |
| Thursday, May 13 |
| » Defeated Braves (7-13), 8-6 | Braves Field (2-0) | 10-10 | Won 2 |
| » Starters: Bill Lee vs Roy Weir | Fifth | 5 out |
| Saturday, May 15 |
| » Lost to Reds (7-12), 3-2 | Crosley Field (0-1) | 10-11 | |
| » Starters: Roy Parmelee vs Lee Grissom | Fifth | 5½ out |
| Sunday, May 16 |
| » Lost to Reds (8-12), 3-2 | Crosley Field (0-2) | 10-12 | Lost 2 |
| » Starters: Charlie Root vs Al Hollingsworth | Fifth | 6½ out |
| Monday, May 17 |
| » Defeated Reds (8-13), 5-2 | Crosley Field (1-2) | 11-12 | |
| » Starters: Bill Lee vs Whitey Moore | Fifth | 6 out |
| Wednesday, May 19 |
| » Defeated Dodgers (11-12), 3-1 | Wrigley Field (3-3) | 12-12 | Won 2 |
| » Starters: Harry Eisenstat vs Tex Carleton | Fourth | 5½ out |
| Thursday, May 20 |
| » Defeated Dodgers (11-13), 6-1 | Wrigley Field (4-3) | 13-12 | Won 3 |
| » Starters: Van Mungo vs Roy Parmelee | Fourth | 5½ out |
| Friday, May 21 |
| » Defeated Giants (14-13), 8-5 | Wrigley Field (5-3) | 14-12 | Won 4 |
| » Starters: Hal Schumacher vs Clyde Shoun | Third | 4½ out |
| Saturday, May 22 |
| » Lost to Giants (15-13), 3-2 | Wrigley Field (5-4) | 14-13 | |
| » Starters: Slick Castleman vs Larry French | Fourth | 5½ out |
| Sunday, May 23 |
| » Defeated Braves (11-15), 11-1 | Wrigley Field (6-4) | 15-13 | |
| » Starters: Ira Hutchinson vs Charlie Root | Fourth | 4½ out |
| Monday, May 24 |
| » Lost to Braves (12-15), 3-1 | Wrigley Field (6-5) | 15-14 | |
| » Starters: Lou Fette vs Tex Carleton | Fourth | 4½ out |
| Tuesday, May 25 |
| » Defeated Phillies (11-19), 5-3 | Wrigley Field (7-5) | 16-14 | |
| » Starters: Claude Passeau vs Bill Lee | Fourth | 3½ out |
| Wednesday, May 26 |
| » Lost to Phillies (12-19), 6-1 | Wrigley Field (7-6) | 16-15 | |
| » Starters: Wayne LaMaster vs Roy Parmelee | Fourth | 4 out |
| Thursday, May 27 |
| » Lost to Phillies (13-19), 11-2 | Wrigley Field (7-7) | 16-16 | Lost 2 |
| » Starters: Bucky Walters vs Larry French | Fourth | 4½ out |
| Friday, May 28 |
| » Defeated Reds (10-21), 12-3 | Wrigley Field (8-7) | 17-16 | |
| » Starters: Whitey Moore vs Charlie Root | Fourth | 4½ out |
| Saturday, May 29 |
| » Defeated Reds (10-22), 4-2 | Wrigley Field (9-7) | 18-16 | Won 2 |
| » Starters: Johnny Vander Meer vs Tex Carleton | Fourth | 3½ out |
| » Defeated Reds (10-23), 4-2 | Wrigley Field (10-7) | 19-16 | Won 3 |
| » Starters: Paul Derringer vs Roy Parmelee | Fourth | 3½ out |
| Sunday, May 30 |
| » Defeated Reds (10-24), 7-1 | Wrigley Field (11-7) | 20-16 | Won 4 |
| » Starters: Lee Grissom vs Larry French | Third | 3½ out |
| Monday, May 31 |
| » Defeated Cardinals (18-17), 4-2 | Sportsman's Park III (2-2) | 21-16 | Won 5 |
| » Starters: Bill Lee vs Lon Warneke | Third | 2½ out |
| » Defeated Cardinals (18-18), 6-3 | Sportsman's Park III (3-2) | 22-16 | Won 6 |
| » Starters: Clay Bryant vs Dizzy Dean | Third | 2½ out |
| Wednesday, June 2 |
| » Defeated Giants (24-16), 2-1 | Polo Grounds V (2-2) | 23-16 | Won 7 |
| » Starters: Clyde Shoun vs Harry Gumbert | Third | 2½ out |
| Friday, June 4 |
| » Defeated Giants (24-17), 6-5 | Polo Grounds V (3-2) | 24-16 | Won 8 |
| » Starters: Larry French vs Carl Hubbell | Third | 1½ out |
| » Lost to Giants (25-17), 4-2 | Polo Grounds V (3-3) | 24-17 | |
| » Starters: Bill Lee vs Slick Castleman | Third | 1½ out |
| Saturday, June 5 |
| » Defeated Braves (17-21), 6-3 | Braves Field (3-0) | 25-17 | |
| » Starters: Tex Carleton vs Danny MacFayden | Third | 1½ out |
| Sunday, June 6 |
| » Lost to Braves (18-21), 7-1 | Braves Field (3-1) | 25-18 | |
| » Starters: Charlie Root vs Guy Bush | Third | 1 out |
| » Defeated Braves (18-22), 7-2 | Braves Field (4-1) | 26-18 | |
| » Starters: Roy Parmelee vs Ira Hutchinson | Third | 1 out |
| Wednesday, June 9 |
| » Defeated Dodgers (19-22), 8-4 | Ebbets Field (1-2) | 27-18 | Won 2 |
| » Starters: Larry French vs Luke Hamlin | Second | 1 out |
| Thursday, June 10 |
| » Defeated Dodgers (19-23), 9-3 | Ebbets Field (2-2) | 28-18 | Won 3 |
| » Starters: Bill Lee vs Harry Eisenstat | Second | ½ out |
| Saturday, June 12 |
| » Defeated Phillies (18-27), 10-5 | Baker Bowl (4-0) | 29-18 | Won 4 |
| » Starters: Larry French vs Wayne LaMaster | Second | ½ out |
| Sunday, June 13 |
| » Defeated Phillies (18-28), 16-8 | Baker Bowl (5-0) | 30-18 | Won 5 |
| » Starters: Clyde Shoun vs Claude Passeau | Second | ½ out |
| » Lost to Phillies (19-28), 4-3 | Baker Bowl (5-1) | 30-19 | |
| » Starters: Roy Parmelee vs Hugh Mulcahy | Second | ½ out |
| Tuesday, June 15 |
| » Defeated Braves (20-28), 5-4 | Wrigley Field (12-7) | 31-19 | |
| » Starters: Guy Bush vs Tex Carleton | First | -- |
| Friday, June 18 |
| » Defeated Phillies (20-31), 8-7 | Wrigley Field (13-7) | 32-19 | Won 2 |
| » Starters: Syl Johnson vs Bill Lee | First | -- |
| Saturday, June 19 |
| » Defeated Phillies (20-32), 2-1 | Wrigley Field (14-7) | 33-19 | Won 3 |
| » Starters: Wayne LaMaster vs Larry French | First | -- |
| Sunday, June 20 |
| » Lost to Phillies (21-32), 6-5 | Wrigley Field (14-8) | 33-20 | |
| » Starters: Bucky Walters vs Clay Bryant | First | -- |
| Tuesday, June 22 |
| » Defeated Giants (33-23), 5-0 | Wrigley Field (15-8) | 34-20 | |
| » Starters: Harry Gumbert vs Bill Lee | First | -- |
| Wednesday, June 23 |
| » Lost to Giants (34-23), 8-4 | Wrigley Field (15-9) | 34-21 | |
| » Starters: Carl Hubbell vs Clyde Shoun | First | -- |
| » Major-league debuts: Dutch Meyer (Cubs) |
| Thursday, June 24 |
| » Defeated Giants (34-24), 10-5 | Wrigley Field (16-9) | 35-21 | |
| » Starters: Hal Schumacher vs Larry French | First | -- |
| Friday, June 25 |
| » Defeated Dodgers (24-30), 11-2 | Wrigley Field (17-9) | 36-21 | Won 2 |
| » Starters: Freddie Fitzsimmons vs Tex Carleton | First | -- |
| Saturday, June 26 |
| » Lost to Dodgers (25-30), 2-1 | Wrigley Field (17-10) | 36-22 | |
| » Starters: Waite Hoyt vs Bill Lee | First | -- |
| Sunday, June 27 |
| » Lost to Dodgers (26-30), 8-3 | Wrigley Field (17-11) | 36-23 | Lost 2 |
| » Starters: Van Mungo vs Larry French | First | -- |
| » Lost to Dodgers (27-30), 6-3 | Wrigley Field (17-12) | 36-24 | Lost 3 |
| » Starters: Luke Hamlin vs Charlie Root | First | -- |
| Tuesday, June 29 |
| » Defeated Cardinals (34-25), 11-9 | Sportsman's Park III (4-2) | 37-24 | |
| » Starters: Tex Carleton vs Bob Weiland | First | -- |
| Wednesday, June 30 |
| » Defeated Cardinals (34-26), 9-4 | Sportsman's Park III (5-2) | 38-24 | Won 2 |
| » Starters: Roy Parmelee vs Lon Warneke | First | -- |
| Thursday, July 1 |
| » Defeated Cardinals (34-27), 6-3 | Sportsman's Park III (6-2) | 39-24 | Won 3 |
| » Starters: Bill Lee vs Jim Winford | First | -- |
| Friday, July 2 |
| » Defeated Pirates (35-28), 8-7 | Wrigley Field (18-12) | 40-24 | Won 4 |
| » Starters: Red Lucas vs Larry French | First | -- |
| Saturday, July 3 |
| » Defeated Pirates (35-29), 10-5 | Wrigley Field (19-12) | 41-24 | Won 5 |
| » Starters: Joe Bowman vs Tex Carleton | First | -- |
| Sunday, July 4 |
| » Defeated Pirates (35-30), 8-5 | Wrigley Field (20-12) | 42-24 | Won 6 |
| » Starters: Cy Blanton vs Curt Davis | First | -- |
| » Lost to Pirates (36-30), 7-6 | Wrigley Field (20-13) | 42-25 | |
| » Starters: Bill Swift vs Roy Parmelee | First | -- |
| Monday, July 5 |
| » Defeated Cardinals (36-29), 13-12 | Wrigley Field (21-13) | 43-25 | |
| » Starters: Ray Harrell vs Bill Lee | First | -- |
| » Defeated Cardinals (36-30), 9-7 | Wrigley Field (22-13) | 44-25 | Won 2 |
| » Starters: Jim Winford vs Bill Lee | First | -- |
| Friday, July 9 |
| » Lost to Pirates (39-30), 13-1 | Forbes Field (1-2) | 44-26 | |
| » Starters: Tex Carleton vs Joe Bowman | First | -- |
| Saturday, July 10 |
| » Defeated Pirates (39-31), 2-0 | Forbes Field (2-2) | 45-26 | |
| » Starters: Larry French vs Cy Blanton | First | -- |
| Sunday, July 11 |
| » Lost to Pirates (40-31), 3-2 | Forbes Field (2-3) | 45-27 | |
| » Starters: Bill Lee vs Bill Swift | First | -- |
| Wednesday, July 14 |
| » Lost to Braves (34-41), 2-1 | Braves Field (4-2) | 45-28 | Lost 2 |
| » Starters: Charlie Root vs Jim Turner | Second | 1½ out |
| Thursday, July 15 |
| » Defeated Braves (34-42), 5-1 | Braves Field (5-2) | 46-28 | |
| » Starters: Tex Carleton vs Guy Bush | First | -- |
| Friday, July 16 |
| » Lost to Braves (35-42), 6-1 | Braves Field (5-3) | 46-29 | |
| » Starters: Bill Lee vs Lou Fette | First | -- |
| Future Cub Lee Elia is born in Philadelphia, PA. |
| Saturday, July 17 |
| » Defeated Dodgers (32-42), 8-7 | Ebbets Field (3-2) | 47-29 | |
| » Starters: Larry French vs Max Butcher | First | -- |
| Sunday, July 18 |
| » Defeated Dodgers (32-43), 7-6 | Ebbets Field (4-2) | 48-29 | Won 2 |
| » Starters: Roy Parmelee vs Van Mungo | First | -- |
| » Defeated Dodgers (32-44), 9-4 | Ebbets Field (5-2) | 49-29 | Won 3 |
| » Starters: Curt Davis vs Fred Frankhouse | First | -- |
| Monday, July 19 |
| » Defeated Dodgers (32-45), 9-0 | Ebbets Field (6-2) | 50-29 | Won 4 |
| » Starters: Tex Carleton vs Luke Hamlin | First | -- |
| Wednesday, July 21 |
| » Defeated Phillies (31-50), 4-1 | Baker Bowl (6-1) | 51-29 | Won 5 |
| » Starters: Bill Lee vs Syl Johnson | First | -- |
| » Defeated Phillies (31-51), 6-0 | Baker Bowl (7-1) | 52-29 | Won 6 |
| » Starters: Larry French vs Orville Jorgens | First | -- |
| Thursday, July 22 |
| » Lost to Phillies (32-51), 7-4 | Baker Bowl (7-2) | 52-30 | |
| » Starters: Clyde Shoun vs Claude Passeau | First | -- |
| Friday, July 23 |
| » Defeated Giants (52-33), 11-3 | Polo Grounds V (4-3) | 53-30 | |
| » Starters: Curt Davis vs Carl Hubbell | First | -- |
| Saturday, July 24 |
| » Defeated Giants (52-34), 10-5 | Polo Grounds V (5-3) | 54-30 | Won 2 |
| » Starters: Roy Parmelee vs Cliff Melton | First | -- |
| Sunday, July 25 |
| » Lost to Giants (53-34), 5-0 | Polo Grounds V (5-4) | 54-31 | |
| » Starters: Bill Lee vs Harry Gumbert | First | -- |
| Tuesday, July 27 |
| » Defeated Dodgers (35-49), 5-2 | Wrigley Field (23-13) | 55-31 | |
| » Starters: Luke Hamlin vs Tex Carleton | First | -- |
| Wednesday, July 28 |
| » Defeated Dodgers (35-50), 7-5 | Wrigley Field (24-13) | 56-31 | Won 2 |
| » Starters: Max Butcher vs Larry French | First | -- |
| Thursday, July 29 |
| » Lost to Dodgers (36-50), 10-2 | Wrigley Field (24-14) | 56-32 | |
| » Starters: Fred Frankhouse vs Curt Davis | First | -- |
| Friday, July 30 |
| » Defeated Giants (54-37), 5-3 | Wrigley Field (25-14) | 57-32 | |
| » Starters: Harry Gumbert vs Bill Lee | First | -- |
| Saturday, July 31 |
| » Defeated Giants (54-38), 7-1 | Wrigley Field (26-14) | 58-32 | Won 2 |
| » Starters: Carl Hubbell vs Tex Carleton | First | -- |
| Sunday, August 1 |
| » Defeated Giants (54-39), 5-4 | Wrigley Field (27-14) | 59-32 | Won 3 |
| » Starters: Cliff Melton vs Charlie Root | First | -- |
| Tuesday, August 3 |
| » Defeated Phillies (38-57), 4-1 | Wrigley Field (28-14) | 60-32 | Won 4 |
| » Starters: Syl Johnson vs Bill Lee | First | -- |
| Wednesday, August 4 |
| » Lost to Phillies (39-57), 2-1 | Wrigley Field (28-15) | 60-33 | |
| » Starters: Wayne LaMaster vs Larry French | First | -- |
| Thursday, August 5 |
| » Lost to Phillies (40-57), 4-2 | Wrigley Field (28-16) | 60-34 | Lost 2 |
| » Starters: Bucky Walters vs Clyde Shoun | First | -- |
| Friday, August 6 |
| » Defeated Braves (46-51), 12-6 | Wrigley Field (29-16) | 61-34 | |
| » Starters: Ira Hutchinson vs Tex Carleton | First | -- |
| » Defeated Braves (46-52), 6-2 | Wrigley Field (30-16) | 62-34 | Won 2 |
| » Starters: Guy Bush vs Roy Parmelee | First | -- |
| Future Cub Joe Schaffernoth is born in Trenton, NJ. |
| Saturday, August 7 |
| » Lost to Braves (47-52), 8-6 | Wrigley Field (30-17) | 62-35 | |
| » Starters: Frank Gabler vs Bill Lee | First | -- |
| Sunday, August 8 |
| » Defeated Braves (47-53), 3-0 | Wrigley Field (31-17) | 63-35 | |
| » Starters: Jim Turner vs Tex Carleton | First | -- |
| » Defeated Braves (47-54), 3-2 | Wrigley Field (32-17) | 64-35 | Won 2 |
| » Starters: Lou Fette vs Charlie Root | First | -- |
| Tuesday, August 10 |
| » Lost to Pirates (52-46), 6-5 | Wrigley Field (32-18) | 64-36 | |
| » Starters: Cy Blanton vs Larry French | First | -- |
| Wednesday, August 11 |
| » Defeated Pirates (52-47), 5-1 | Wrigley Field (33-18) | 65-36 | |
| » Starters: Red Lucas vs Clay Bryant | First | -- |
| Thursday, August 12 |
| » Lost to Pirates (53-47), 16-6 | Wrigley Field (33-19) | 65-37 | |
| » Starters: Ed Brandt vs Tex Carleton | First | -- |
| Friday, August 13 |
| » Defeated Reds (41-58), 22-6 | Wrigley Field (34-19) | 66-37 | |
| » Starters: Paul Derringer vs Roy Parmelee | First | -- |
| Saturday, August 14 |
| » Lost to Reds (42-58), 10-5 | Wrigley Field (34-20) | 66-38 | |
| » Starters: Al Hollingsworth vs Curt Davis | First | -- |
| Sunday, August 15 |
| » Lost to Reds (43-58), 13-6 | Wrigley Field (34-21) | 66-39 | Lost 2 |
| » Starters: Lee Grissom vs Tex Carleton | First | -- |
| » Lost to Reds (44-58), 9-8 | Wrigley Field (34-22) | 66-40 | Lost 3 |
| » Starters: Gene Schott vs Clay Bryant | First | -- |
| Monday, August 16 |
| Former Cub Bunk Congalton dies in Cleveland, OH at the age of 63. |
| Tuesday, August 17 |
| » Lost to Pirates (57-48), 4-2 | Forbes Field (2-4) | 66-41 | Lost 4 |
| » Starters: Larry French vs Ed Brandt | First | -- |
| Wednesday, August 18 |
| » Lost to Pirates (58-48), 7-6 | Forbes Field (2-5) | 66-42 | Lost 5 |
| » Starters: Clay Bryant vs Jim Weaver | First | -- |
| Thursday, August 19 |
| » Defeated Pirates (58-49), 7-3 | Forbes Field (3-5) | 67-42 | |
| » Starters: Curt Davis vs Joe Bowman | First | -- |
| Friday, August 20 |
| » Lost to Reds (45-61), 6-4 | Crosley Field (1-3) | 67-43 | |
| » Starters: Roy Parmelee vs Paul Derringer | First | -- |
| Saturday, August 21 |
| » Defeated Reds (45-62), 7-6 | Crosley Field (2-3) | 68-43 | |
| » Starters: Bill Lee vs Al Hollingsworth | First | -- |
| Sunday, August 22 |
| » Defeated Reds (45-63), 4-1 | Crosley Field (3-3) | 69-43 | Won 2 |
| » Starters: Charlie Root vs Lee Grissom | First | -- |
| » Defeated Reds (45-64), 5-2 | Crosley Field (4-3) | 70-43 | Won 3 |
| » Starters: Tex Carleton vs Gene Schott | First | -- |
| Wednesday, August 25 |
| » Lost to Giants (65-45), 8-7 | Polo Grounds V (5-5) | 70-44 | |
| » Starters: Bill Lee vs Carl Hubbell | First | -- |
| » Lost to Giants (66-45), 4-2 | Polo Grounds V (5-6) | 70-45 | Lost 2 |
| » Starters: Larry French vs Harry Gumbert | First | -- |
| Saturday, August 28 |
| » Lost to Braves (56-60), 3-1 | Braves Field (5-4) | 70-46 | Lost 3 |
| » Starters: Tex Carleton vs Lou Fette | First | -- |
| » Defeated Braves (56-61), 10-7 | Braves Field (6-4) | 71-46 | |
| » Starters: Charlie Root vs Guy Bush | First | -- |
| Sunday, August 29 |
| » Lost to Phillies (50-66), 10-3 | Baker Bowl (7-3) | 71-47 | |
| » Starters: Bill Lee vs Hugh Mulcahy | First | -- |
| » Defeated Phillies (50-67), 2-1 | Baker Bowl (8-3) | 72-47 | |
| » Starters: Larry French vs Wayne LaMaster | First | -- |
| Tuesday, August 31 |
| » Defeated Dodgers (48-69), 4-2 | Ebbets Field (7-2) | 73-47 | Won 2 |
| » Starters: Tex Carleton vs Fred Frankhouse | First | -- |
| Wednesday, September 1 |
| » Lost to Dodgers (49-69), 6-4 | Ebbets Field (7-3) | 73-48 | |
| » Starters: Curt Davis vs Roy Henshaw | Second | 1 out |
| Thursday, September 2 |
| » Lost to Dodgers (50-69), 4-3 | Ebbets Field (7-4) | 73-49 | Lost 2 |
| » Starters: Bill Lee vs Luke Hamlin | Second | 1 out |
| Sunday, September 5 |
| » Lost to Pirates (64-59), 7-0 | Wrigley Field (34-23) | 73-50 | Lost 3 |
| » Starters: Red Lucas vs Larry French | Second | 2 out |
| » Lost to Pirates (65-59), 4-1 | Wrigley Field (34-24) | 73-51 | Lost 4 |
| » Starters: Ed Brandt vs Clay Bryant | Second | 2 out |
| Monday, September 6 |
| » Lost to Reds (50-71), 7-3 | Wrigley Field (34-25) | 73-52 | Lost 5 |
| » Starters: Paul Derringer vs Tex Carleton | Second | 3 out |
| » Defeated Reds (50-72), 2-1 | Wrigley Field (35-25) | 74-52 | |
| » Starters: Lee Grissom vs Curt Davis | Second | 3 out |
| Tuesday, September 7 |
| » Defeated Cardinals (66-60), 8-5 | Wrigley Field (36-25) | 75-52 | Won 2 |
| » Starters: Sheriff Blake vs Bill Lee | Second | 2½ out |
| Wednesday, September 8 |
| » Defeated Cardinals (66-61), 4-0 | Wrigley Field (37-25) | 76-52 | Won 3 |
| » Starters: Dizzy Dean vs Larry French | Second | 2½ out |
| Thursday, September 9 |
| » Lost to Cardinals (67-61), 8-2 | Wrigley Field (37-26) | 76-53 | |
| » Starters: Lon Warneke vs Charlie Root | Second | 3 out |
| Friday, September 10 |
| » Defeated Cardinals (67-62), 11-0 | Wrigley Field (38-26) | 77-53 | |
| » Starters: Bob Weiland vs Tex Carleton | Second | 2 out |
| Saturday, September 11 |
| » Defeated Pirates (70-61), 5-4 | Forbes Field (4-5) | 78-53 | Won 2 |
| » Starters: Curt Davis vs Russ Bauers | Second | 1½ out |
| Sunday, September 12 |
| » Defeated Pirates (70-62), 5-0 | Forbes Field (5-5) | 79-53 | Won 3 |
| » Starters: Larry French vs Red Lucas | Second | 1½ out |
| » Lost to Pirates (71-62), 4-2 | Forbes Field (5-6) | 79-54 | |
| » Starters: Bill Lee vs Jim Tobin | Second | 1½ out |
| Tuesday, September 14 |
| » Lost to Braves (67-67), 9-0 | Wrigley Field (38-27) | 79-55 | Lost 2 |
| » Starters: Johnny Lanning vs Tex Carleton | Second | 2½ out |
| » Lost to Braves (68-67), 4-2 | Wrigley Field (38-28) | 79-56 | Lost 3 |
| » Starters: Danny MacFayden vs Clay Bryant | Second | 2½ out |
| Wednesday, September 15 |
| » Defeated Braves (68-68), 5-2 | Wrigley Field (39-28) | 80-56 | |
| » Starters: Milt Shoffner vs Curt Davis | Second | 2½ out |
| Future Cub Charley Smith is born in Charleston, SC. |
| Thursday, September 16 |
| » Lost to Braves (69-68), 7-0 | Wrigley Field (39-29) | 80-57 | |
| » Starters: Jim Turner vs Bill Lee | Second | 3½ out |
| Friday, September 17 |
| » Defeated Phillies (54-82), 10-2 | Wrigley Field (40-29) | 81-57 | |
| » Starters: Wayne LaMaster vs Larry French | Second | 3½ out |
| Saturday, September 18 |
| » Defeated Phillies (54-83), 9-3 | Wrigley Field (41-29) | 82-57 | Won 2 |
| » Starters: Claude Passeau vs Tex Carleton | Second | 2½ out |
| Sunday, September 19 |
| » Defeated Dodgers (61-79), 2-1 | Wrigley Field (42-29) | 83-57 | Won 3 |
| » Starters: Max Butcher vs Curt Davis | Second | 2½ out |
| Monday, September 20 |
| » Defeated Dodgers (61-80), 5-4 | Wrigley Field (43-29) | 84-57 | Won 4 |
| » Starters: Fred Frankhouse vs Bill Lee | Second | 2½ out |
| Tuesday, September 21 |
| » Defeated Giants (85-54), 7-5 | Wrigley Field (44-29) | 85-57 | Won 5 |
| » Starters: Harry Gumbert vs Larry French | Second | 1½ out |
| Wednesday, September 22 |
| » Lost to Giants (86-54), 6-0 | Wrigley Field (44-30) | 85-58 | |
| » Starters: Cliff Melton vs Tex Carleton | Second | 2½ out |
| Thursday, September 23 |
| » Lost to Giants (87-54), 8-7 | Wrigley Field (44-31) | 85-59 | Lost 2 |
| » Starters: Hal Schumacher vs Curt Davis | Second | 3½ out |
| Saturday, September 25 |
| » Defeated Cardinals (78-67), 5-2 | Sportsman's Park III (7-2) | 86-59 | |
| » Starters: Tex Carleton vs Lon Warneke | Second | 3½ out |
| Sunday, September 26 |
| » Lost to Cardinals (79-67), 6-5 | Sportsman's Park III (7-3) | 86-60 | |
| » Starters: Bill Lee vs Bob Weiland | Second | 4 out |
| » Defeated Cardinals (79-68), 8-5 | Sportsman's Park III (8-3) | 87-60 | |
| » Starters: Larry French vs Howie Krist | Second | 4 out |
| Monday, September 27 |
| » Defeated Reds (56-91), 7-4 | Crosley Field (5-3) | 88-60 | Won 2 |
| » Starters: Curt Davis vs Al Hollingsworth | Second | 4½ out |
| Tuesday, September 28 |
| » Defeated Reds (56-92), 2-0 | Crosley Field (6-3) | 89-60 | Won 3 |
| » Starters: Clay Bryant vs Peaches Davis | Second | 4 out |
| Wednesday, September 29 |
| » Defeated Reds (56-93), 3-0 | Crosley Field (7-3) | 90-60 | Won 4 |
| » Starters: Tex Carleton vs Gene Schott | Second | 3½ out |
| Thursday, September 30 |
| » Defeated Reds (56-94), 4-1 | Crosley Field (8-3) | 91-60 | Won 5 |
| » Starters: Larry French vs Joe Cascarella | Second | 3 out |
| Friday, October 1 |
| » Lost to Cardinals (80-71), 4-1 | Wrigley Field (44-32) | 91-61 | |
| » Starters: Si Johnson vs Bill Lee | Second | 3 out |
| Saturday, October 2 |
| » Defeated Cardinals (80-72), 5-1 | Wrigley Field (45-32) | 92-61 | |
| » Starters: Bob Weiland vs Curt Davis | Second | 3 out |
| Sunday, October 3 |
| » Defeated Cardinals (80-73), 6-4 | Wrigley Field (46-32) | 93-61 | Won 2 |
| » Starters: Howie Krist vs Clay Bryant | Second | 3 out |
| » Major-league debuts: Kirby Higbe (Cubs) |
| Wednesday, November 17 |
| Future Cub Jim Brewer is born in Merced, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |
